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Volumn 199, Issue 3, 2003, Pages 275-288

Apoptosis and melanoma: Molecular mechanisms

Author keywords

Anti apoptotic molecules; CMM; Cutaneous malignant melanoma; Pro apoptotic molecules; Programmed cell death

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; ENDOTHELIN; FAS ANTIGEN; FAS LIGAND; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; INTEGRIN; MYC PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; PROTEIN KINASE; PROTEIN MCL 1; PROTEIN P53; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR; SURVIVIN; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 0037372013     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1300     Document Type: Review
Times cited : (220)

References (121)
  • 1
    • 0030829777 scopus 로고    scopus 로고
    • Apoptosis: An overview
    • Wyllie AH. Apoptosis: an overview. Br Med Bull 1997; 53: 451-465.
    • (1997) Br. Med. Bull. , vol.53 , pp. 451-465
    • Wyllie, A.H.1
  • 2
    • 0024347970 scopus 로고
    • Monoclonal antibody-mediated tumor regression by induction of apoptosis
    • Trauth BC, Klas C, Peters AM, et al. Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 1989; 245: 301-305.
    • (1989) Science , vol.245 , pp. 301-305
    • Trauth, B.C.1    Klas, C.2    Peters, A.M.3
  • 3
    • 0034067779 scopus 로고    scopus 로고
    • Death effector domain of a mammalian apoptosis mediator, FADD, induces bacterial cell death
    • Lee SW, Ko YG, Bang S, Kim KS, Kim S. Death effector domain of a mammalian apoptosis mediator, FADD, induces bacterial cell death. Mol Microbiol 2000; 35: 1540-1549.
    • (2000) Mol. Microbiol. , vol.35 , pp. 1540-1549
    • Lee, S.W.1    Ko, Y.G.2    Bang, S.3    Kim, K.S.4    Kim, S.5
  • 4
    • 0035896406 scopus 로고    scopus 로고
    • A docking model of key components of the DISC complex: Death domain superfamily interactions redefined
    • Weber CH, Vincenz C. A docking model of key components of the DISC complex: death domain superfamily interactions redefined. FEBS Lett 2001; 492: 171-176.
    • (2001) FEBS Lett. , vol.492 , pp. 171-176
    • Weber, C.H.1    Vincenz, C.2
  • 5
    • 0037016707 scopus 로고    scopus 로고
    • The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif
    • Martins LM, Iaccarino I, Tenev T, et al. The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif. J Biol Chem 2002; 277: 439-444.
    • (2002) J. Biol. Chem. , vol.277 , pp. 439-444
    • Martins, L.M.1    Iaccarino, I.2    Tenev, T.3
  • 6
    • 0036365079 scopus 로고    scopus 로고
    • Bax and bh3-domain-only proteins in p53-mediated apoptosis
    • Wu X, Deng Y. Bax and bh3-domain-only proteins in p53-mediated apoptosis. Front Biosci 2002; 7: D151-156.
    • (2002) Front Biosci. , vol.7
    • Wu, X.1    Deng, Y.2
  • 7
    • 0141805544 scopus 로고    scopus 로고
    • Stressed to death: Regulation of apoptotic signaling pathways by the heat shock proteins
    • 2001: RE1
    • Beere HM. Stressed to death: regulation of apoptotic signaling pathways by the heat shock proteins. Sci STKE 2001; 2001: RE1.
    • (2001) Sci. STKE
    • Beere, H.M.1
  • 8
    • 0030237476 scopus 로고    scopus 로고
    • p53: Integrating the complexity
    • Hall PA, Meek D, Lane DP. p53: integrating the complexity. J Pathol 1996; 180: 1-5.
    • (1996) J. Pathol. , vol.180 , pp. 1-5
    • Hall, P.A.1    Meek, D.2    Lane, D.P.3
  • 9
    • 0026561121 scopus 로고
    • Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
    • Donehower LA, Harvey M, Slagle BL, et al. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 1992; 356: 215-221.
    • (1992) Nature , vol.356 , pp. 215-221
    • Donehower, L.A.1    Harvey, M.2    Slagle, B.L.3
  • 10
    • 0027528673 scopus 로고
    • High levels of p53 protein in UV-irradiated normal human skin
    • Hall PA, McKee PH, Menage HD, Dover R, Lane DP. High levels of p53 protein in UV-irradiated normal human skin. Oncogene 1993; 8: 203-207.
    • (1993) Oncogene , vol.8 , pp. 203-207
    • Hall, P.A.1    McKee, P.H.2    Menage, H.D.3    Dover, R.4    Lane, D.P.5
  • 11
    • 85047696563 scopus 로고    scopus 로고
    • Regulation of the mitochondrial checkpoint in p53-mediated apoptosis confers resistance to cell death
    • Henry H, Thomas A, Shen Y, White E. Regulation of the mitochondrial checkpoint in p53-mediated apoptosis confers resistance to cell death. Oncogene 2002; 21: 748-760.
    • (2002) Oncogene , vol.21 , pp. 748-760
    • Henry, H.1    Thomas, A.2    Shen, Y.3    White, E.4
  • 12
    • 0031889132 scopus 로고    scopus 로고
    • Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
    • Sakahira H, Enari M, Nagata S. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 1998; 391: 96-99.
    • (1998) Nature , vol.391 , pp. 96-99
    • Sakahira, H.1    Enari, M.2    Nagata, S.3
  • 13
    • 0036497307 scopus 로고    scopus 로고
    • p53-independent induction of Fas and apoptosis in leukemic cells by an adenosine derivative, C1-IB-MECA
    • Kim SG, Ravi G, Hoffmann C, et al. p53-independent induction of Fas and apoptosis in leukemic cells by an adenosine derivative, C1-IB-MECA. Biochem Pharmacol 2002; 63: 871-880.
    • (2002) Biochem. Pharmacol. , vol.63 , pp. 871-880
    • Kim, S.G.1    Ravi, G.2    Hoffmann, C.3
  • 14
    • 0032549042 scopus 로고    scopus 로고
    • Frequent mutations of the p53 gene in cutaneous melanoma of the nodular type
    • Akslen LA, Monstad SE, Larsen B, Straume O, Ogreid D. Frequent mutations of the p53 gene in cutaneous melanoma of the nodular type. Int J Cancer 1998; 79: 91-95.
    • (1998) Int. J. Cancer , vol.79 , pp. 91-95
    • Akslen, L.A.1    Monstad, S.E.2    Larsen, B.3    Straume, O.4    Ogreid, D.5
  • 15
    • 0029833974 scopus 로고    scopus 로고
    • Lack of p53 mutations and loss of heterozygosity in non-cultured human melanocytic lesions
    • Papp T, Jafari M, Schiffmann D. Lack of p53 mutations and loss of heterozygosity in non-cultured human melanocytic lesions. J Cancer Res Clin Oncol 1996; 122: 541-548.
    • (1996) J. Cancer Res. Clin. Oncol. , vol.122 , pp. 541-548
    • Papp, T.1    Jafari, M.2    Schiffmann, D.3
  • 17
    • 0025173845 scopus 로고
    • p53: Oncogene or anti-oncogene?
    • Lane DP, Benchimol S. p53: oncogene or anti-oncogene? Genes Dev 1990; 4: 1-8.
    • (1990) Genes Dev. , vol.4 , pp. 1-8
    • Lane, D.P.1    Benchimol, S.2
  • 18
    • 0034038805 scopus 로고    scopus 로고
    • Concurrent Ki-67 and p53 immunolabeling in cutaneous melanocytic neoplasms: An adjunct for recognition of the vertical growth phase in malignant melanomas?
    • Kaleem Z, Lind AC, Humphrey PA, et al. Concurrent Ki-67 and p53 immunolabeling in cutaneous melanocytic neoplasms: an adjunct for recognition of the vertical growth phase in malignant melanomas? Mod Pathol 2000; 13: 217-222.
    • (2000) Mod. Pathol. , vol.13 , pp. 217-222
    • Kaleem, Z.1    Lind, A.C.2    Humphrey, P.A.3
  • 19
    • 0027232043 scopus 로고
    • Overexpression of p53 is a late event in the development of malignant melanoma
    • Lassam NJ, From L, Kahn HJ. Overexpression of p53 is a late event in the development of malignant melanoma. Cancer Res 1993; 53: 2235-2238.
    • (1993) Cancer Res. , vol.53 , pp. 2235-2238
    • Lassam, N.J.1    From, L.2    Kahn, H.J.3
  • 20
    • 0026609019 scopus 로고
    • Expression of mutant p53 proteins in lung cancer correlates with the class of p53 gene mutation
    • Bodner SM, Minna JD, Jensen SM, et al. Expression of mutant p53 proteins in lung cancer correlates with the class of p53 gene mutation. Oncogene 1992; 7: 743-749.
    • (1992) Oncogene , vol.7 , pp. 743-749
    • Bodner, S.M.1    Minna, J.D.2    Jensen, S.M.3
  • 22
    • 0028807606 scopus 로고
    • Immunohistochemical detection of p53 in melanomas with rare p53 gene mutations is associated with mdm-2 overexpression
    • Poremba C, Yandell DW, Metze D, Kamanabrou D, Bocker W, Dockhorn-Dworniczak B. Immunohistochemical detection of p53 in melanomas with rare p53 gene mutations is associated with mdm-2 overexpression. Oncol Res 1995; 7: 331-339.
    • (1995) Oncol. Res. , vol.7 , pp. 331-339
    • Poremba, C.1    Yandell, D.W.2    Metze, D.3    Kamanabrou, D.4    Bocker, W.5    Dockhorn-Dworniczak, B.6
  • 23
    • 0027818553 scopus 로고
    • p53 protein detected by immunohistochemical staining is not always mutant
    • MacGeoch C, Barnes DM, Newton JA, et al. p53 protein detected by immunohistochemical staining is not always mutant. Dis Markers 1993; 11: 239-250.
    • (1993) Dis. Markers , vol.11 , pp. 239-250
    • MacGeoch, C.1    Barnes, D.M.2    Newton, J.A.3
  • 24
    • 0035843169 scopus 로고    scopus 로고
    • Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
    • Soengas MS, Capodieci P, Polsky D, et al. Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature 2001; 409: 207-211.
    • (2001) Nature , vol.409 , pp. 207-211
    • Soengas, M.S.1    Capodieci, P.2    Polsky, D.3
  • 25
    • 0035843322 scopus 로고    scopus 로고
    • Cancer: Death and methylation
    • 141
    • Jones PA. Cancer: death and methylation. Nature 2001; 409: 141, 143-144.
    • (2001) Nature , vol.409 , pp. 143-144
    • Jones, P.A.1
  • 26
    • 0031838967 scopus 로고    scopus 로고
    • Expression of Bcl-2 family members in human melanocytes, in melanoma metastases and in melanoma cell lines
    • Selzer E, Schlagbauer-Wadl H, Okamoto I, Pehamberger H, Potter R, Jansen B. Expression of Bcl-2 family members in human melanocytes, in melanoma metastases and in melanoma cell lines. Melanoma Res 1998; 8: 197-203.
    • (1998) Melanoma Res. , vol.8 , pp. 197-203
    • Selzer, E.1    Schlagbauer-Wadl, H.2    Okamoto, I.3    Pehamberger, H.4    Potter, R.5    Jansen, B.6
  • 27
    • 0033635733 scopus 로고    scopus 로고
    • BH3-only proteins-essential initiators of apoptotic cell death
    • Huang DC, Strasser A. BH3-only proteins-essential initiators of apoptotic cell death. Cell 2000; 103: 839-842.
    • (2000) Cell , vol.103 , pp. 839-842
    • Huang, D.C.1    Strasser, A.2
  • 29
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91: 479-489.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3
  • 30
    • 0028206341 scopus 로고
    • BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax
    • Yin XM, Oltvai ZN, Korsmeyer SJ. BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature 1994; 369: 321-323.
    • (1994) Nature , vol.369 , pp. 321-323
    • Yin, X.M.1    Oltvai, Z.N.2    Korsmeyer, S.J.3
  • 31
    • 0026688162 scopus 로고
    • Apoptotic cell death induced by c-myc is inhibited by bcl-2
    • Bissonnette RP, Echeverri F, Mahboubi A, Green DR. Apoptotic cell death induced by c-myc is inhibited by bcl-2. Nature 1992; 359: 552-554.
    • (1992) Nature , vol.359 , pp. 552-554
    • Bissonnette, R.P.1    Echeverri, F.2    Mahboubi, A.3    Green, D.R.4
  • 32
    • 0031850559 scopus 로고    scopus 로고
    • Expression of apoptosis regulators in cutaneous malignant melanoma
    • Tang L, Tron VA, Reed JC, et al. Expression of apoptosis regulators in cutaneous malignant melanoma. Clin Cancer Res 1998; 4: 1865-1871.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 1865-1871
    • Tang, L.1    Tron, V.A.2    Reed, J.C.3
  • 33
    • 0032858974 scopus 로고    scopus 로고
    • Malignant melanoma arising from nevi, p53, p16, and Bcl-2: Expression in benign versus malignant components
    • Radhi JM. Malignant melanoma arising from nevi, p53, p16, and Bcl-2: expression in benign versus malignant components. J Cutan Med Surg 1999; 3: 293-297.
    • (1999) J. Cutan. Med. Surg. , vol.3 , pp. 293-297
    • Radhi, J.M.1
  • 34
    • 0034949925 scopus 로고    scopus 로고
    • Quercetin inhibits the invasion and mobility of murine melanoma B16-BL6 cells through inducing apoptosis via decreasing Bcl-2 expression
    • Zhang X, Xu Q, Saiki I. Quercetin inhibits the invasion and mobility of murine melanoma B16-BL6 cells through inducing apoptosis via decreasing Bcl-2 expression. Clin Exp Metastasis 2000; 18: 415-421.
    • (2000) Clin. Exp. Metastasis , vol.18 , pp. 415-421
    • Zhang, X.1    Xu, Q.2    Saiki, I.3
  • 35
    • 0034670025 scopus 로고    scopus 로고
    • TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria
    • Thomas WD, Zhang XD, Franco AV, Nguyen T, Hersey P. TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria. J Immunol 2000; 165: 5612-5620.
    • (2000) J. Immunol. , vol.165 , pp. 5612-5620
    • Thomas, W.D.1    Zhang, X.D.2    Franco, A.V.3    Nguyen, T.4    Hersey, P.5
  • 36
    • 0033547350 scopus 로고    scopus 로고
    • TRAIL causes cleavage of bid by caspase-8 and loss of mitochondrial membrane potential resulting in apoptosis in BJAB cells
    • Yamada H, Tada-Oikawa S, Uchida A, Kawanishi S. TRAIL causes cleavage of bid by caspase-8 and loss of mitochondrial membrane potential resulting in apoptosis in BJAB cells. Biochem Biophys Res Commun 1999; 265: 130-133.
    • (1999) Biochem. Biophys Res. Commun. , vol.265 , pp. 130-133
    • Yamada, H.1    Tada-Oikawa, S.2    Uchida, A.3    Kawanishi, S.4
  • 37
    • 0028609620 scopus 로고
    • Mcl-1, a member of the Bcl-2 family, delays apoptosis induced by c-Myc overexpression in Chinese hamster ovary cells
    • Reynolds JE, Yang T, Qian L, et al. Mcl-1, a member of the Bcl-2 family, delays apoptosis induced by c-Myc overexpression in Chinese hamster ovary cells. Cancer Res 1994; 54: 6348-6352.
    • (1994) Cancer Res. , vol.54 , pp. 6348-6352
    • Reynolds, J.E.1    Yang, T.2    Qian, L.3
  • 38
    • 0028290446 scopus 로고
    • Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2
    • Gottschalk AR, Boise LH, Thompson CB, Quintans J. Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2. Proc Natl Acad Sci USA 1994; 91: 7350-7354.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7350-7354
    • Gottschalk, A.R.1    Boise, L.H.2    Thompson, C.B.3    Quintans, J.4
  • 39
    • 0029782288 scopus 로고    scopus 로고
    • Down-regulation of apoptosis-related bcl-2 but not bcl-xL or bax proteins in multidrug-resistant MCF-7/Adr human breast cancer cells
    • Ogretmen B, Safa AR. Down-regulation of apoptosis-related bcl-2 but not bcl-xL or bax proteins in multidrug-resistant MCF-7/Adr human breast cancer cells. Int J Cancer 1996; 67: 608-614.
    • (1996) Int. J. Cancer , vol.67 , pp. 608-614
    • Ogretmen, B.1    Safa, A.R.2
  • 40
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: Integrating mammalian biology
    • Locksley RM, Killeen N, Lenardo MJ. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 2001; 104: 487-501.
    • (2001) Cell , vol.104 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 42
    • 0345036008 scopus 로고
    • Recombinant 55-kDa tumor necrosis factor (TNF) receptor: Stoichiometry of binding to TNF alpha and TNF beta and inhibition of TNF activity
    • Loetscher H, Gentz R, Zulauf M, et al. Recombinant 55-kDa tumor necrosis factor (TNF) receptor: stoichiometry of binding to TNF alpha and TNF beta and inhibition of TNF activity. J Biol Chem 1991; 266: 18 324-18 329.
    • (1991) J. Biol. Chem. , vol.266 , pp. 18324-18329
    • Loetscher, H.1    Gentz, R.2    Zulauf, M.3
  • 43
    • 0027275490 scopus 로고
    • A novel domain within the 55 kd TNF receptor signals cell death
    • Tartaglia LA, Ayres TM, Wong GH, Goeddel DV. A novel domain within the 55 kd TNF receptor signals cell death. Cell 1993; 74: 845-853.
    • (1993) Cell , vol.74 , pp. 845-853
    • Tartaglia, L.A.1    Ayres, T.M.2    Wong, G.H.3    Goeddel, D.V.4
  • 44
    • 0029068115 scopus 로고
    • Expression of type A and B tumor necrosis factor (TNF) receptors on melanoma cells can be regulated by dbc-AMP and IFN gamma
    • Carrel S, Hartmann F, Salvi S, Albrecht H, Schreyer M, Rimoldi D. Expression of type A and B tumor necrosis factor (TNF) receptors on melanoma cells can be regulated by dbc-AMP and IFN gamma. Int J Cancer 1995; 62: 76-83.
    • (1995) Int. J. Cancer , vol.62 , pp. 76-83
    • Carrel, S.1    Hartmann, F.2    Salvi, S.3    Albrecht, H.4    Schreyer, M.5    Rimoldi, D.6
  • 45
    • 0032530612 scopus 로고    scopus 로고
    • Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
    • Griffith TS, Chin WA, Jackson GC, Lynch DH, Kubin MZ. Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells. J Immunol 1998; 161: 2833-2840.
    • (1998) J. Immunol. , vol.161 , pp. 2833-2840
    • Griffith, T.S.1    Chin, W.A.2    Jackson, G.C.3    Lynch, D.H.4    Kubin, M.Z.5
  • 46
    • 0033579807 scopus 로고    scopus 로고
    • Efficient adenoviral transfer of NF-kappaB inhibitor sensitizes melanoma to tumor necrosis factor-mediated apoptosis
    • Bakker TR, Reed D, Renno T, Jongeneel CV. Efficient adenoviral transfer of NF-kappaB inhibitor sensitizes melanoma to tumor necrosis factor-mediated apoptosis. Int J Cancer 1999; 80: 320-323.
    • (1999) Int. J. Cancer , vol.80 , pp. 320-323
    • Bakker, T.R.1    Reed, D.2    Renno, T.3    Jongeneel, C.V.4
  • 47
    • 0035119322 scopus 로고    scopus 로고
    • Triggering of antitumor activity through melanoma-specific transduction of a constitutively active tumor necrosis factor (TNF) R1 chimeric receptor in the absence of TNF-alpha
    • Bazzoni F, Regalia E. Triggering of antitumor activity through melanoma-specific transduction of a constitutively active tumor necrosis factor (TNF) R1 chimeric receptor in the absence of TNF-alpha. Cancer Res 2001; 61: 1050-1057.
    • (2001) Cancer Res. , vol.61 , pp. 1050-1057
    • Bazzoni, F.1    Regalia, E.2
  • 48
  • 49
    • 0034677563 scopus 로고    scopus 로고
    • Role of TRAF2/GCK in melanoma sensitivity to UV-induced apoptosis
    • Ivanov VN, Kehrl JH, Ronai Z. Role of TRAF2/GCK in melanoma sensitivity to UV-induced apoptosis. Oncogene 2000; 19: 933-942.
    • (2000) Oncogene , vol.19 , pp. 933-942
    • Ivanov, V.N.1    Kehrl, J.H.2    Ronai, Z.3
  • 50
    • 0028845253 scopus 로고
    • Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase
    • Pombo CM, Kehrl JH, Sanchez I, et al. Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase. Nature 1995; 377: 750-754.
    • (1995) Nature , vol.377 , pp. 750-754
    • Pombo, C.M.1    Kehrl, J.H.2    Sanchez, I.3
  • 51
    • 0031017618 scopus 로고    scopus 로고
    • MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1
    • Malinin NL, Boldin MP, Kovalenko AV, Wallach D. MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1. Nature 1997; 385: 540-544.
    • (1997) Nature , vol.385 , pp. 540-544
    • Malinin, N.L.1    Boldin, M.P.2    Kovalenko, A.V.3    Wallach, D.4
  • 52
    • 0030954209 scopus 로고    scopus 로고
    • The CARD domain: A new apoptotic signalling motif
    • Hofmann K, Bucher P, Tschopp J. The CARD domain: a new apoptotic signalling motif. Trends Biochem Sci 1997; 22: 155-156.
    • (1997) Trends Biochem. Sci. , vol.22 , pp. 155-156
    • Hofmann, K.1    Bucher, P.2    Tschopp, J.3
  • 53
    • 0032910169 scopus 로고    scopus 로고
    • Apoptosis control by death and decoy receptors
    • Ashkenazi A, Dixit VM. Apoptosis control by death and decoy receptors. Curr Opin Cell Biol 1999; 11: 255-260.
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 255-260
    • Ashkenazi, A.1    Dixit, V.M.2
  • 54
    • 0011444717 scopus 로고    scopus 로고
    • Mechanisms of resistance of normal cells to TRAIL induced apoptosis vary between different cell types
    • Zhang XD, Nguyen T, Thomas WD, Sanders JE, Hersey P. Mechanisms of resistance of normal cells to TRAIL induced apoptosis vary between different cell types. FEBS Lett 2000; 482: 193-199.
    • (2000) FEBS Lett. , vol.482 , pp. 193-199
    • Zhang, X.D.1    Nguyen, T.2    Thomas, W.D.3    Sanders, J.E.4    Hersey, P.5
  • 55
    • 0013583837 scopus 로고    scopus 로고
    • Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma
    • Zhang XD, Franco A, Myers K, Gray C, Nguyen T, Hersey P. Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma. Cancer Res 1999; 59: 2747-2753.
    • (1999) Cancer Res. , vol.59 , pp. 2747-2753
    • Zhang, X.D.1    Franco, A.2    Myers, K.3    Gray, C.4    Nguyen, T.5    Hersey, P.6
  • 56
    • 0031414749 scopus 로고    scopus 로고
    • The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
    • Degli-Esposti MA, Dougall WC, Smolak PJ, Waugh JY, Smith CA, Goodwin RG. The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity 1997; 7: 813-820.
    • (1997) Immunity , vol.7 , pp. 813-820
    • Degli-Esposti, M.A.1    Dougall, W.C.2    Smolak, P.J.3    Waugh, J.Y.4    Smith, C.A.5    Goodwin, R.G.6
  • 57
    • 0031405585 scopus 로고    scopus 로고
    • TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB
    • Schneider P, Thome M, Burns K, et al. TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB. Immunity 1997; 7: 831-836.
    • (1997) Immunity , vol.7 , pp. 831-836
    • Schneider, P.1    Thome, M.2    Burns, K.3
  • 58
    • 0034527878 scopus 로고    scopus 로고
    • Immunologically-mediated tumour cell apoptosis: The role of TRAIL in T cell and cytokine-mediated responses to melanoma
    • Nguyen T, Thomas W, Zhang XD, Gray C, Hersey P. Immunologically-mediated tumour cell apoptosis: the role of TRAIL in T cell and cytokine-mediated responses to melanoma. Forum (Genova) 2000; 10: 243-252.
    • (2000) Forum (Genova) , vol.10 , pp. 243-252
    • Nguyen, T.1    Thomas, W.2    Zhang, X.D.3    Gray, C.4    Hersey, P.5
  • 59
    • 0032169208 scopus 로고    scopus 로고
    • TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in Fas ligand-resistant melanoma cells and mediates CD4 T cell killing of target cells
    • Thomas WD, Hersey P. TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in Fas ligand-resistant melanoma cells and mediates CD4 T cell killing of target cells. J Immunol 1998; 161: 2195-2200.
    • (1998) J. Immunol. , vol.161 , pp. 2195-2200
    • Thomas, W.D.1    Hersey, P.2
  • 60
    • 0033974084 scopus 로고    scopus 로고
    • Molecular determinants of response to TRAIL in killing of normal and cancer cells
    • Kim K, Fisher MJ, Xu SQ, el-Deiry WS. Molecular determinants of response to TRAIL in killing of normal and cancer cells. Clin Cancer Res 2000; 6: 335-346.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 335-346
    • Kim, K.1    Fisher, M.J.2    Xu, S.Q.3    el-Deiry, W.S.4
  • 61
    • 0035340285 scopus 로고    scopus 로고
    • The role of NF-kappa B in TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of melanoma cells
    • Franco AV, Zhang XD, Van Berkel E, et al. The role of NF-kappa B in TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of melanoma cells. J Immunol 2001; 166: 5337-5345.
    • (2001) J. Immunol. , vol.166 , pp. 5337-5345
    • Franco, A.V.1    Zhang, X.D.2    Van Berkel, E.3
  • 62
    • 0028973059 scopus 로고
    • Regulation of IkB alpha phosphorylation by PKC- and Ca(2+)-dependent signal transduction pathways
    • Steffan NM, Bren GD, Frantz B, Tocci MJ, O'Neill EA, Paya CV. Regulation of IkB alpha phosphorylation by PKC- and Ca(2+)-dependent signal transduction pathways. J Immunol 1995; 155: 4685-4691.
    • (1995) J. Immunol. , vol.155 , pp. 4685-4691
    • Steffan, N.M.1    Bren, G.D.2    Frantz, B.3    Tocci, M.J.4    O'Neill, E.A.5    Paya, C.V.6
  • 63
    • 0025899613 scopus 로고
    • A labile repressor acts through the NFkB-like binding sites of the human urokinase gene
    • Novak U, Cocks BG, Hamilton JA. A labile repressor acts through the NFkB-like binding sites of the human urokinase gene. Nucleic Acids Res 1991; 19: 3389-3393.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 3389-3393
    • Novak, U.1    Cocks, B.G.2    Hamilton, J.A.3
  • 64
    • 0032508414 scopus 로고    scopus 로고
    • NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 1998; 281: 1680-1683.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin A.S., Jr.5
  • 65
    • 0027145632 scopus 로고
    • Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
    • Suda T, Takahashi T, Golstein P, Nagata S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 1993; 75: 1169-1178.
    • (1993) Cell , vol.75 , pp. 1169-1178
    • Suda, T.1    Takahashi, T.2    Golstein, P.3    Nagata, S.4
  • 66
    • 0034604053 scopus 로고    scopus 로고
    • Resistance to CD95/Fas-induced and ceramide-mediated apoptosis of human melanoma cells is caused by a defective mitochondrial cytochrome c release
    • Raisova M, Bektas M, Wieder T, et al. Resistance to CD95/Fas-induced and ceramide-mediated apoptosis of human melanoma cells is caused by a defective mitochondrial cytochrome c release. FEBS Lett 2000; 473: 27-32.
    • (2000) FEBS Lett. , vol.473 , pp. 27-32
    • Raisova, M.1    Bektas, M.2    Wieder, T.3
  • 67
    • 0033534446 scopus 로고    scopus 로고
    • Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death
    • Gross A, Yin XM, Wang K, et al. Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death. J Biol Chem 1999; 274: 1156-1163.
    • (1999) J. Biol. Chem. , vol.274 , pp. 1156-1163
    • Gross, A.1    Yin, X.M.2    Wang, K.3
  • 68
    • 7344248004 scopus 로고    scopus 로고
    • Human melanoma-reactive CD4+ and CD8+ CTL clones resist Fas ligand-induced apoptosis and use Fas/Fas ligand-independent mechanisms for tumor killing
    • Rivoltini L, Radrizzani M, Accomero P, et al. Human melanoma-reactive CD4+ and CD8+ CTL clones resist Fas ligand-induced apoptosis and use Fas/Fas ligand-independent mechanisms for tumor killing. J Immunol 1998; 161: 1220-1230.
    • (1998) J. Immunol. , vol.161 , pp. 1220-1230
    • Rivoltini, L.1    Radrizzani, M.2    Accomero, P.3
  • 69
    • 10544232277 scopus 로고    scopus 로고
    • Melanoma cell expression of Fas(Apo-1/CD95) ligand: Implications for tumor immune escape
    • Hahne M, Rimoldi D, Schroter M, et al. Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape. Science 1996; 274: 1363-1366.
    • (1996) Science , vol.274 , pp. 1363-1366
    • Hahne, M.1    Rimoldi, D.2    Schroter, M.3
  • 70
    • 0000293602 scopus 로고    scopus 로고
    • Alterations of Fas (Apo-1/CD95) gene in cutaneous malignant melanoma
    • Shin MS, Park WS, Kim SY, et al. Alterations of Fas (Apo-1/CD95) gene in cutaneous malignant melanoma. Am J Pathol 1999; 154: 1785-1791.
    • (1999) Am. J. Pathol. , vol.154 , pp. 1785-1791
    • Shin, M.S.1    Park, W.S.2    Kim, S.Y.3
  • 73
    • 0035720233 scopus 로고    scopus 로고
    • The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis
    • Raisova M, Hossini AM, Eberle J, et al. The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis. J Invest Dermatol 2001; 117: 333-340.
    • (2001) J. Invest. Dermatol. , vol.117 , pp. 333-340
    • Raisova, M.1    Hossini, A.M.2    Eberle, J.3
  • 74
    • 0031570098 scopus 로고    scopus 로고
    • Role of Fas ligand (CD95L) in immune escape: The tumor cell strikes back
    • Walker PR, Saas P, Dietrich PY. Role of Fas ligand (CD95L) in immune escape: the tumor cell strikes back. J Immunol 1997; 158: 4521-4524.
    • (1997) J. Immunol. , vol.158 , pp. 4521-4524
    • Walker, P.R.1    Saas, P.2    Dietrich, P.Y.3
  • 75
    • 0033778257 scopus 로고    scopus 로고
    • Plasma Fas ligand, an inducer of apoptosis, and plasma soluble Fas, an inhibitor of apoptosis, in advanced melanoma
    • Mouawad R, Khayat D, Soubrane C. Plasma Fas ligand, an inducer of apoptosis, and plasma soluble Fas, an inhibitor of apoptosis, in advanced melanoma. Melanoma Res 2000; 10: 461-467.
    • (2000) Melanoma Res. , vol.10 , pp. 461-467
    • Mouawad, R.1    Khayat, D.2    Soubrane, C.3
  • 76
    • 0033215243 scopus 로고    scopus 로고
    • Fas-induced apoptosis in human malignant melanoma cell lines is associated with the activation of the p34(cdc2)-related PITSLRE protein kinases
    • Ariza ME, Broome-Powell M, Lahti JM, Kidd VJ, Nelson MA. Fas-induced apoptosis in human malignant melanoma cell lines is associated with the activation of the p34(cdc2)-related PITSLRE protein kinases. J Biol Chem 1999; 274: 28 505-28 513.
    • (1999) J. Biol. Chem. , vol.274 , pp. 28505-28513
    • Ariza, M.E.1    Broome-Powell, M.2    Lahti, J.M.3    Kidd, V.J.4    Nelson, M.A.5
  • 78
    • 0033554886 scopus 로고    scopus 로고
    • Abnormalities in the p34cdc2-related PITSLRE protein kinase gene complex (CDC2L) on chromosome band 1p36 in melanoma
    • Nelson MA, Ariza ME, Yang JM, et al. Abnormalities in the p34cdc2-related PITSLRE protein kinase gene complex (CDC2L) on chromosome band 1p36 in melanoma. Cancer Genet Cytogenet 1999; 108: 91-99.
    • (1999) Cancer Genet. Cytogenet. , vol.108 , pp. 91-99
    • Nelson, M.A.1    Ariza, M.E.2    Yang, J.M.3
  • 79
    • 12944333194 scopus 로고    scopus 로고
    • Type I consensus interferon (CIFN) gene transfer into human melanoma cells up-regulates p53 and enhances cisplatin-induced apoptosis: Implications for new therapeutic strategies with IFN-alpha
    • Mecchia M, Matarrese P, Malorni W, et al. Type I consensus interferon (CIFN) gene transfer into human melanoma cells up-regulates p53 and enhances cisplatin-induced apoptosis: implications for new therapeutic strategies with IFN-alpha. Gene Ther 2000; 7: 167-179.
    • (2000) Gene. Ther. , vol.7 , pp. 167-179
    • Mecchia, M.1    Matarrese, P.2    Malorni, W.3
  • 80
    • 0034895641 scopus 로고    scopus 로고
    • Preferential induction of apoptosis by interferon (ifn)-beta compared with ifn-alpha2: Correlation with trail/apo21 induction in melanoma cell lines
    • Chawla-Sarkar M, Leaman DW, Borden EC. Preferential induction of apoptosis by interferon (ifn)-beta compared with ifn-alpha2: correlation with trail/apo21 induction in melanoma cell lines. Clin Cancer Res 2001; 7: 1821-1831.
    • (2001) Clin Cancer Res. , vol.7 , pp. 1821-1831
    • Chawla-Sarkar, M.1    Leaman, D.W.2    Borden, E.C.3
  • 81
    • 0030864875 scopus 로고    scopus 로고
    • Nitric oxide-mediated apoptosis of K-1735 melanoma cells is associated with downregulation of Bcl-2
    • Xie K, Wang Y, Huang S, et al. Nitric oxide-mediated apoptosis of K-1735 melanoma cells is associated with downregulation of Bcl-2. Oncogene 1997; 15: 771-779.
    • (1997) Oncogene , vol.15 , pp. 771-779
    • Xie, K.1    Wang, Y.2    Huang, S.3
  • 82
    • 0033609672 scopus 로고    scopus 로고
    • Heterogenous susceptibility to CD95-induced apoptosis in melanoma cells correlates with bcl-2 and bcl-x expression and is sensitive to modulation by interferon-gamma
    • Ugurel S, Seiter S, Rappl G, Stark A, Tilgen W, Reinhold U. Heterogenous susceptibility to CD95-induced apoptosis in melanoma cells correlates with bcl-2 and bcl-x expression and is sensitive to modulation by interferon-gamma. Int J Cancer 1999; 82: 727-736.
    • (1999) Int. J. Cancer , vol.82 , pp. 727-736
    • Ugurel, S.1    Seiter, S.2    Rappl, G.3    Stark, A.4    Tilgen, W.5    Reinhold, U.6
  • 83
    • 0026518279 scopus 로고
    • Loss of c-kit expression in cultured melanoma cells
    • Lassam N, Bickford S. Loss of c-kit expression in cultured melanoma cells. Oncogene 1992; 7: 51-56.
    • (1992) Oncogene , vol.7 , pp. 51-56
    • Lassam, N.1    Bickford, S.2
  • 84
    • 0027197555 scopus 로고
    • KIT ligand (mast cell growth factor) inhibits the growth of KIT-expressing melanoma cells
    • Zakut R, Perlis R, Eliyahu S, et al. KIT ligand (mast cell growth factor) inhibits the growth of KIT-expressing melanoma cells. Oncogene 1993; 8: 2221-2229.
    • (1993) Oncogene , vol.8 , pp. 2221-2229
    • Zakut, R.1    Perlis, R.2    Eliyahu, S.3
  • 85
    • 0032479996 scopus 로고    scopus 로고
    • Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis
    • Huang S, Jean D, Luca M, Tainsky MA, Bar-Eli M. Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis. Embo J 1998; 17: 4358-4369.
    • (1998) Embo J. , vol.17 , pp. 4358-4369
    • Huang, S.1    Jean, D.2    Luca, M.3    Tainsky, M.A.4    Bar-Eli, M.5
  • 86
    • 0031753290 scopus 로고    scopus 로고
    • Molecular changes in human melanoma metastasis
    • Luca MR, Bar-Eli M. Molecular changes in human melanoma metastasis. Histol Histopathol 1998; 13: 1225-1231.
    • (1998) Histol. Histopathol. , vol.13 , pp. 1225-1231
    • Luca, M.R.1    Bar-Eli, M.2
  • 87
    • 0026793058 scopus 로고
    • Progression of human cutaneous melanoma is associated with loss of expression of c-kit proto-oncogene receptor
    • Natali PG, Nicotra MR, Winkler AB, Cavaliere R, Bigotti A, Ullrich A. Progression of human cutaneous melanoma is associated with loss of expression of c-kit proto-oncogene receptor. Int J Cancer 1992; 52: 197-201.
    • (1992) Int. J. Cancer , vol.52 , pp. 197-201
    • Natali, P.G.1    Nicotra, M.R.2    Winkler, A.B.3    Cavaliere, R.4    Bigotti, A.5    Ullrich, A.6
  • 88
    • 0035901914 scopus 로고    scopus 로고
    • Myc down-regulation induces apoptosis in M14 melanoma cells by increasing p27(kip1) levels
    • D'Agnano I, Valentini A, Fornari C, et al. Myc down-regulation induces apoptosis in M14 melanoma cells by increasing p27(kip1) levels. Oncogene 2001; 20: 2814-2825.
    • (2001) Oncogene , vol.20 , pp. 2814-2825
    • D'Agnano, I.1    Valentini, A.2    Fornari, C.3
  • 89
    • 0026642195 scopus 로고
    • Induction of apoptosis in fibroblasts by c-myc protein
    • Evan GI, Wyllie AH, Gilbert CS, et al. Induction of apoptosis in fibroblasts by c-myc protein. Cell 1992; 69: 119-128.
    • (1992) Cell , vol.69 , pp. 119-128
    • Evan, G.I.1    Wyllie, A.H.2    Gilbert, C.S.3
  • 90
    • 0028935119 scopus 로고
    • Alterations of c-myc expression by antisense oligodeoxynucleotides enhance the induction of apoptosis in HL-60 cells
    • Kimura S, Maekawa T, Hirakawa K, Murakami A, Abe T. Alterations of c-myc expression by antisense oligodeoxynucleotides enhance the induction of apoptosis in HL-60 cells. Cancer Res 1995; 55: 1379-1384.
    • (1995) Cancer Res. , vol.55 , pp. 1379-1384
    • Kimura, S.1    Maekawa, T.2    Hirakawa, K.3    Murakami, A.4    Abe, T.5
  • 91
    • 0032575705 scopus 로고    scopus 로고
    • A matter of life and cell death
    • Evan G, Littlewood T. A matter of life and cell death. Science 1998; 281: 1317-1322.
    • (1998) Science , vol.281 , pp. 1317-1322
    • Evan, G.1    Littlewood, T.2
  • 92
    • 0031963158 scopus 로고    scopus 로고
    • c-myc antisense oligodeoxynucleotides enhance the efficacy of cisplatin in melanoma chemotherapy in vitro and in nude mice
    • Citro, G, D'Agnano I, Leonetti C, et al. c-myc antisense oligodeoxynucleotides enhance the efficacy of cisplatin in melanoma chemotherapy in vitro and in nude mice. Cancer Res 1998; 58: 283-289.
    • (1998) Cancer Res. , vol.58 , pp. 283-289
    • Citro, G.1    D'Agnano, I.2    Leonetti, C.3
  • 93
    • 0029873193 scopus 로고    scopus 로고
    • Antitumor effect of c-myc antisense phosphorothioate oligodeoxynucleotides on human melanoma cells in vitro and in mice
    • Leonetti C, D'Agnano I, Lozupone F, et al. Antitumor effect of c-myc antisense phosphorothioate oligodeoxynucleotides on human melanoma cells in vitro and in mice. J Natl Cancer Inst 1996; 88: 419-429.
    • (1996) J. Natl. Cancer Inst. , vol.88 , pp. 419-429
    • Leonetti, C.1    D'Agnano, I.2    Lozupone, F.3
  • 94
    • 0032852873 scopus 로고    scopus 로고
    • Increase of cisplatin sensitivity by c-myc antisense oligodeoxynucleotides in a human metastatic melanoma inherently resistant to cisplatin
    • Leonetti C, Biroccio A, Candiloro A, et al. Increase of cisplatin sensitivity by c-myc antisense oligodeoxynucleotides in a human metastatic melanoma inherently resistant to cisplatin. Clin Cancer Res 1999; 5: 2588-2595.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2588-2595
    • Leonetti, C.1    Biroccio, A.2    Candiloro, A.3
  • 95
    • 0034948497 scopus 로고    scopus 로고
    • c-Myc down-regulation increases susceptibility to cisplatin through reactive oxygen species-mediated apoptosis in M14 human melanoma cells
    • Biroccio A, Benassi B, Amodei S, Gabellini C, Del Bufalo D, Zupi G. c-Myc down-regulation increases susceptibility to cisplatin through reactive oxygen species-mediated apoptosis in M14 human melanoma cells. Mol Pharmacol 2001; 60: 174-182.
    • (2001) Mol. Pharmacol. , vol.60 , pp. 174-182
    • Biroccio, A.1    Benassi, B.2    Amodei, S.3    Gabellini, C.4    Del Bufalo, D.5    Zupi, G.6
  • 96
    • 0035793557 scopus 로고    scopus 로고
    • Livin, a novel inhibitor of apoptosis protein family member
    • Kasof GM, Gomes BC. Livin, a novel inhibitor of apoptosis protein family member. J Biol Chem 2001; 276: 3238-3246.
    • (2001) J. Biol. Chem. , vol.276 , pp. 3238-3246
    • Kasof, G.M.1    Gomes, B.C.2
  • 97
    • 0033082995 scopus 로고    scopus 로고
    • IAP family proteins: Suppressors of apoptosis
    • Deveraux QL, Reed JC. IAP family proteins: suppressors of apoptosis. Genes Dev 1999; 13: 239-252.
    • (1999) Genes Dev. , vol.13 , pp. 239-252
    • Deveraux, Q.L.1    Reed, J.C.2
  • 98
    • 0030746636 scopus 로고    scopus 로고
    • A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
    • Ambrosini G, Adida C, Altieri DC. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 1997; 3: 917-921.
    • (1997) Nat. Med. , vol.3 , pp. 917-921
    • Ambrosini, G.1    Adida, C.2    Altieri, D.C.3
  • 99
    • 0032403126 scopus 로고    scopus 로고
    • IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs
    • Tamm I, Wang Y, Sausville E, et al. IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res 1998; 58: 5315-5320.
    • (1998) Cancer Res. , vol.58 , pp. 5315-5320
    • Tamm, I.1    Wang, Y.2    Sausville, E.3
  • 100
    • 0032506524 scopus 로고    scopus 로고
    • Control of apoptosis and mitotic spindle checkpoint by survivin
    • Li F, Ambrosini G, Chu EY, et al. Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 1998; 396: 580-584.
    • (1998) Nature , vol.396 , pp. 580-584
    • Li, F.1    Ambrosini, G.2    Chu, E.Y.3
  • 101
    • 0033397882 scopus 로고    scopus 로고
    • Expression and targeting of the apoptosis inhibitor, survivin, in human melanoma
    • Grossman D, McNiff JM, Li F, Altieri DC. Expression and targeting of the apoptosis inhibitor, survivin, in human melanoma. J Invest Dermatol 1999; 113: 1076-1081.
    • (1999) J. Invest. Dermatol. , vol.113 , pp. 1076-1081
    • Grossman, D.1    McNiff, J.M.2    Li, F.3    Altieri, D.C.4
  • 103
    • 0034597630 scopus 로고    scopus 로고
    • ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas
    • Vucic D, Stennicke HR, Pisabarro MT, Salvesen GS, Dixit VM. ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas. Curr Biol 2000; 10: 1359-1366.
    • (2000) Curr. Biol. , vol.10 , pp. 1359-1366
    • Vucic, D.1    Stennicke, H.R.2    Pisabarro, M.T.3    Salvesen, G.S.4    Dixit, V.M.5
  • 104
    • 0037023712 scopus 로고    scopus 로고
    • SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)
    • Vucic D, Deshayes K, Ackerly H, et al. SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP). J Biol Chem 2002; 277: 12 275-12 279.
    • (2002) J. Biol. Chem. , vol.277 , pp. 12275-12279
    • Vucic, D.1    Deshayes, K.2    Ackerly, H.3
  • 105
    • 0013543367 scopus 로고
    • The human endothelin family: Three structurally and pharmacologically distinct isopeptides predicted by three separate genes
    • Inoue A, Yanagisawa M, Kimura S, et al. The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci USA 1989; 86: 2863-2867.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 2863-2867
    • Inoue, A.1    Yanagisawa, M.2    Kimura, S.3
  • 106
    • 0025605930 scopus 로고
    • Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor
    • Sakurai T, Yanagisawa M, Takuwa Y, et al. Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature 1990; 348: 732-735.
    • (1990) Nature , vol.348 , pp. 732-735
    • Sakurai, T.1    Yanagisawa, M.2    Takuwa, Y.3
  • 107
    • 0029921677 scopus 로고    scopus 로고
    • Endothelin-1-induced mitogenic responses of Chinese hamster ovary cells expressing human endothelin A: The role of a wortmannin-sensitive signaling pathway
    • Sugawara F, Ninomiya H, Okamoto Y, et al. Endothelin-1-induced mitogenic responses of Chinese hamster ovary cells expressing human endothelin A: the role of a wortmannin-sensitive signaling pathway. Mol Pharmacol 1996; 49: 447-457.
    • (1996) Mol. Pharmacol. , vol.49 , pp. 447-457
    • Sugawara, F.1    Ninomiya, H.2    Okamoto, Y.3
  • 109
    • 0030475088 scopus 로고    scopus 로고
    • Multiple roles for endothelin in melanocyte development: Regulation of progenitor number and stimulation of differentiation
    • Reid K, Turnley AM, Maxwell GD, et al. Multiple roles for endothelin in melanocyte development: regulation of progenitor number and stimulation of differentiation. Development 1996; 122: 3911-3919.
    • (1996) Development , vol.122 , pp. 3911-3919
    • Reid, K.1    Turnley, A.M.2    Maxwell, G.D.3
  • 110
    • 0028332744 scopus 로고
    • Human melanoma cells express functional endothelin-1 receptors
    • Yohn JJ, Smith C, Stevens T, et al. Human melanoma cells express functional endothelin-1 receptors. Biochem Biophys Res Commun 1994; 201: 449-457.
    • (1994) Biochem. Biophys Res. Commun. , vol.201 , pp. 449-457
    • Yohn, J.J.1    Smith, C.2    Stevens, T.3
  • 111
    • 0033039244 scopus 로고    scopus 로고
    • Downregulation of endothelin B receptor in human melanoma cell lines parallel to differentiation genes
    • Eberle J, Weitmann S, Thieck O, Pech H, Paul M, Orfanos CE. Downregulation of endothelin B receptor in human melanoma cell lines parallel to differentiation genes. J Invest Dermatol 1999; 112: 925-932.
    • (1999) J. Invest. Dermatol. , vol.112 , pp. 925-932
    • Eberle, J.1    Weitmann, S.2    Thieck, O.3    Pech, H.4    Paul, M.5    Orfanos, C.E.6
  • 112
    • 0029670157 scopus 로고    scopus 로고
    • Decreased ET(B) receptor expression in human metastatic melanoma cells
    • Kikuchi K, Nakagawa H, Kadono T, et al. Decreased ET(B) receptor expression in human metastatic melanoma cells. Biochem Biophys Res Commun 1996; 219: 734-739.
    • (1996) Biochem. Biophys Res. Commun. , vol.219 , pp. 734-739
    • Kikuchi, K.1    Nakagawa, H.2    Kadono, T.3
  • 113
    • 0033613134 scopus 로고    scopus 로고
    • An endothelin receptor B antagonist inhibits growth and induces cell death in human melanoma cells in vitro and in vivo
    • Lahav R, Heffner G, Patterson PH. An endothelin receptor B antagonist inhibits growth and induces cell death in human melanoma cells in vitro and in vivo. Proc Natl Acad Sci USA 1999; 96: 11 496-11 500.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 11496-11500
    • Lahav, R.1    Heffner, G.2    Patterson, P.H.3
  • 114
    • 0030035278 scopus 로고    scopus 로고
    • Adhesion molecules in melanoma: More than just superglue?
    • Mason MD, Allman R, Quibell M. Adhesion molecules in melanoma: more than just superglue? J R Soc Med 1996; 89: 393-395.
    • (1996) J. R. Soc. Med. , vol.89 , pp. 393-395
    • Mason, M.D.1    Allman, R.2    Quibell, M.3
  • 115
    • 0026935755 scopus 로고
    • Disintegrins: RGD-containing proteins which inhibit cell/matrix interactions (adhesion) and cell/cell interactions (aggregation) via the integrin receptors
    • Williams JA. Disintegrins: RGD-containing proteins which inhibit cell/matrix interactions (adhesion) and cell/cell interactions (aggregation) via the integrin receptors. Pathol Biol (Paris) 1992; 40: 813-821.
    • (1992) Pathol. Biol. (Paris) , vol.40 , pp. 813-821
    • Williams, J.A.1
  • 116
    • 0026542056 scopus 로고
    • Integrin expression in human melanoma cells with differing invasive and metastatic properties
    • Gehlsen KR, Davis GE, Sriramarao P. Integrin expression in human melanoma cells with differing invasive and metastatic properties. Clin Exp Metastasis 1992; 10: 111-120.
    • (1992) Clin. Exp. Metastasis , vol.10 , pp. 111-120
    • Gehlsen, K.R.1    Davis, G.E.2    Sriramarao, P.3
  • 117
    • 0029087823 scopus 로고
    • bcl-2 expression in melanocytic nevi: Insights into the biology of dermal maturation
    • Morales-Ducret CR, van de Rijn M, Smoller BR. bcl-2 expression in melanocytic nevi: insights into the biology of dermal maturation. Arch Dermatol 1995; 131: 915-918.
    • (1995) Arch. Dermatol. , vol.131 , pp. 915-918
    • Morales-Ducret, C.R.1    van de Rijn, M.2    Smoller, B.R.3
  • 118
    • 0033014996 scopus 로고    scopus 로고
    • Apoptosis, Fas and Fas-ligand expression in melanocytic tumors
    • Sprecher E, Bergman R, Meilick A, et al. Apoptosis, Fas and Fas-ligand expression in melanocytic tumors. J Cutan Pathol 1999; 26: 72-77.
    • (1999) J. Cutan. Pathol. , vol.26 , pp. 72-77
    • Sprecher, E.1    Bergman, R.2    Meilick, A.3
  • 119
    • 0345390840 scopus 로고    scopus 로고
    • Expression of the proliferation and apoptosis-associated CAS protein in benign and malignant cutaneous melanocytic lesions
    • Boni R, Wellmann A, Man YG, Hofbauer G, Brinkmann U. Expression of the proliferation and apoptosis-associated CAS protein in benign and malignant cutaneous melanocytic lesions. Am J Dermatopathol 1999; 21: 125-128.
    • (1999) Am. J. Dermatopathol. , vol.21 , pp. 125-128
    • Boni, R.1    Wellmann, A.2    Man, Y.G.3    Hofbauer, G.4    Brinkmann, U.5
  • 120
    • 0345435175 scopus 로고    scopus 로고
    • Human melanoma cell line UV responses show independency of p53 function
    • Haapajarvi T, Pitkanen K, Laiho M. Human melanoma cell line UV responses show independency of p53 function. Cell Growth Differ 1999; 10: 163-171.
    • (1999) Cell Growth Differ. , vol.10 , pp. 163-171
    • Haapajarvi, T.1    Pitkanen, K.2    Laiho, M.3
  • 121
    • 0034660614 scopus 로고    scopus 로고
    • p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-kappaB activity and Fas expression
    • Ivanov VN, Ronai Z. p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-kappaB activity and Fas expression. Oncogene 2000; 19: 3003-3012.
    • (2000) Oncogene , vol.19 , pp. 3003-3012
    • Ivanov, V.N.1    Ronai, Z.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.