The Keap1-Nrf2 system as an in vivo sensor for electrophiles

Nitric Oxide - Biology and Chemistry

Volumn 25, Issue 2, 2011, Pages 153-160

  Uruno, Akira ^a   Motohashi, Hozumi ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

ARE EpRE; Electrophile; Oxidative stress; Reactive cysteine; Transcription

Indexed keywords

BRUSATOL; CULLIN; CULLIN 3; CURCUMIN; ELECTROPHILE; HOMODIMER; KELCH LIKE ECH ASSOCIATED PROTEIN 1; NITRIC OXIDE; OLTIPRAZ; OXIDIZING AGENT; PROTEASOME; REACTIVE CYSTEINE RESIDUE; SULFORAPHANE; TRANSCRIPTION FACTOR MAF; TRANSCRIPTION FACTOR NRF2; TRITERPENOID; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ANTIOXIDANT ACTIVITY; AUTOPHAGY; CANCER CELL; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CARCINOGENESIS; CELL PROLIFERATION; CELL PROTECTION; CHEMICAL MODIFICATION; CONFERENCE PAPER; COVALENT BOND; DIMERIZATION; DRUG TARGETING; ELECTROPHILIC STRESS; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; HUMAN; IN VIVO STUDY; METABOLIC DISORDER; MOLECULAR SENSOR; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; UBIQUITINATION; XENOBIOTIC STRESS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; AUTOPHAGY; CELL NUCLEUS; CELL PROLIFERATION; CYTOPROTECTION; CYTOSKELETAL PROTEINS; GENE EXPRESSION REGULATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAF TRANSCRIPTION FACTORS, SMALL; METABOLIC DETOXICATION, DRUG; MICE; MOLECULAR SEQUENCE DATA; NEOPLASMS; NF-E2-RELATED FACTOR 2; NITRIC OXIDE; OXIDATIVE STRESS; PROTEASOME ENDOPEPTIDASE COMPLEX; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTIONAL ACTIVATION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; XENOBIOTICS;

MUS;

EID: 80051545287     PISSN: 10898603     EISSN: 10898611     Source Type: Journal    
DOI: 10.1016/j.niox.2011.02.007     Document Type: Conference Paper

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