Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth

Cancer Research

Volumn 68, Issue 5, 2008, Pages 1303-1309

  Ohta, Tsutomu ^a   Iijima, Kumiko ^a,b   Miyamoto, Mamiko ^a   Nakahara, Izumi ^a,b   Tanaka, Hiroshi ^b   Ohtsuji, Makiko ^c,d   Suzuki, Takafumi ^c,d   Kobayashi, Akira ^c,d   Yokota, Jun ^a   Sakiyama, Tokuki ^a   Shibata, Tatsuhiro ^a   Yamamoto, Masayuki ^c,d   Hirohashi, Setsuo ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b Tokyo Medical and Dental University ^*  (Japan)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; DRUG METABOLIZING ENZYME; KELCH LIKE ECH ASSOCIATED PROTEIN 1; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER PATIENT; CANCER RESISTANCE; CELL PROTECTION; CONTROLLED STUDY; ELECTROPHILIC STRESS; EMBRYO; FIBROBLAST; GENE; GENE IDENTIFICATION; GENE TARGETING; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; JAPAN; KEAP1 GENE; LUNG CANCER; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOMATIC MUTATION; UPREGULATION;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUNG NEOPLASMS; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS;

EID: 40449107193     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-07-5003     Document Type: Article

References (22)

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