Sulforaphane protects against cisplatin-induced nephrotoxicity

Toxicology Letters

Volumn 192, Issue 3, 2010, Pages 278-285

  Guerrero Beltrán, Carlos Enrique ^a   Calderón Oliver, Mariel ^a   Tapia, Edilia ^b   Medina Campos, Omar N ^a   Sánchez González, Dolores Javier ^c   Martínez Martínez, Claudia María ^c   Ortiz Vega, Karla Mariana ^b   Franco, Martha ^b   Pedraza Chaverri, José ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b INSTITUTO NACIONAL DE CARDIOLOGÍA IGNACIO CHÁVEZ   (Mexico)

^c Universidad del Ejercito y Fuerza Aerea   (Mexico)

Author keywords

Cisplatin; Nephrotoxicity; Nrf2; Oxidative nitrosative stress; Renoprotection; Sulforaphane

Indexed keywords

CATALASE; CISPLATIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; SULFORAPHANE; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL NUCLEUS; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; EPITHELIUM CELL; HISTOPATHOLOGY; IMMUNOFLUORESCENCE TEST; INCUBATION TIME; KIDNEY DYSFUNCTION; KIDNEY EPITHELIUM; MALE; NEPHROTOXICITY; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN TRANSPORT; RAT; RENAL PROTECTION; SWINE;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTICARCINOGENIC AGENTS; ANTINEOPLASTIC AGENTS; CELL DEATH; CELL NUCLEUS; CELL SURVIVAL; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; KIDNEY; LLC-PK1 CELLS; MALE; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; RATS; RATS, WISTAR; SWINE; THIOCYANATES;

ANIMALIA; RATTUS NORVEGICUS;

EID: 75349110758     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.11.007     Document Type: Article

References (26)

1. Ali B.H., and Al Moundhri M.S. Agents ameliorating or augmenting the nephrotoxicity of cisplatin and other platinum compounds: a review of some recent research. Food Chem. Toxicol. 44 (2006) 1173-1183
2. Angeloni C., Leoncini E., Malaguti M., Angelini S., Hrelia P., and Hrelia S. Modulation of phase II enzymes by sulforaphane: implications for its cardioprotective potential. J. Agric. Food Chem. 57 (2009) 5615-5622
3. Chirino Y.I., Hernández-Pando R., and Pedraza-Chaverri J. Peroxynitrite decomposition catalyst ameliorates renal damage and protein nitration in cisplatin-induced nephrotoxicity in rats. BMC Pharmacol. 4 (2004) 20
4. Chirino Y.I., Sánchez-González D.J., Martínez-Martínez C.M., Cruz C., and Pedraza-Chaverri J. Protective effects of apocynin against cisplatin-induced oxidative stress and nephrotoxicity. Toxicology 245 (2008) 18-23
5. Chirino Y.I., Trujillo J., Sanchez-Gonzalez D.J., Martinez-Martinez C.M., Cruz C., Bobadilla N.A., and Pedraza-Chaverri J. Selective iNOS inhibition reduces renal damage induced by cisplatin. Toxicol. Lett. 176 (2008) 48-57
6. Chirino Y.I., and Pedraza-Chaverri J. Role of oxidative and nitrosative stress in cisplatin-induced nephrotoxicity. Exp. Toxicol. Pathol. 61 (2009) 223-242
7. Dinkova-Kostova A.T. Phytochemicals as protectors against ultraviolet radiation: versatility of effects and mechanisms. Planta Med. 74 (2008) 1548-1559
8. Dinkova-Kostova A.T., and Talalay P. Direct and indirect antioxidant properties of inducers of cytoprotective proteins. Mol. Nutr. Food Res. 52 Suppl. 1 (2008) S128-S138
9. Fahey J.W., and Talalay P. Antioxidant functions of sulforaphane: a potent inducer of phase II detoxication enzymes. Food Chem. Toxicol. 37 (1999) 973-979
10. Fernández-Checa J.C., and Kaplowitz N. The use of monochlorobimane to determine hepatic GSH levels and synthesis. Anal. Biochem. 190 (1990) 212-219
11. Gérard-Monnier D., Erdelmeier I., Régnard K., Moze-Henry N., Yadan J.C., and Chaudière J. Reactions of 1-methyl-2-phenylindole with malondialdehyde and 4-hydroxyalkenals. Analytical applications to a colorimetric assay of lipid peroxidation. Chem. Res. Toxicol. 11 (1998) 1176-1183
12. Innamorato N.G., Rojo A.I., García-Yagüe A.J., Yamamoto M., de Ceballos M.L., and Cuadrado A. The transcription factor Nrf2 is a therapeutic target against brain inflammation. J. Immunol. 181 (2008) 680-689
13. Juge N., Mithen R.F., and Traka M. Molecular basis for chemoprevention by SFN: a comprehensive review. Cell Mol. Life Sci. 64 (2007) 1105-1127
14. 1 cells and rats. Biol. Pharm. Bull. 29 (2006) 2436-2441
15. Lebwohl D., and Canetta R. Clinical development of platinum complexes in cancer therapy: an historical perspective and an update. Eur. J. Cancer 34 (1998) 1522-1534
16. Long L.H., and Halliwell B. Antioxidant and prooxidant abilities of foods and beverages. Methods Enzymol. 335 (2001) 181-190
17. Orozco-Ibarra M., Estrada-Sánchez A.M., Massieu L., and Pedraza-Chaverrí J. Heme oxygenase-1 induction prevents neuronal damage triggered during mitochondrial inhibition: role of CO and bilirubin. Int. J. Biochem. Cell Biol. 41 (2009) 1304-1314
18. Pabla N., and Dong Z. Cisplatin nephrotoxicity: mechanisms and renoprotective strategies. Kidney Int. 73 (2008) 994-1007
19. Pedraza-Chaverri J., Maldonado P., Medina-Campos O.N., Olivares-Corichi I.M., Granados-Silvestre M.A., Hernández-Pando R., and Ibarra-Rubio M.E. Garlic ameliorates gentamicin nephrotoxicity: relation to antioxidant enzymes. Free Radic. Biol. Med. 29 (2000) 602-611
20. Pedraza-Chaverri J., Yam-Canul P., Chirino Y.I., Sánchez-González D.J., Martínez-Martínez C.M., Cruz C., and Medina-Campos O.N. Protective effects of garlic powder against potassium dichromate-induced oxidative stress and nephrotoxicity. Food Chem. Toxicol. 46 (2008) 619-627
21. Pérez-Rojas J.M., Cruz C., García-López P., Sánchez-González D.J., Martínez-Martínez C.M., Ceballos G., Espinosa E., Meléndez-Zajgla J., and Pedraza-Chaverri J. Renoprotection by α-mangostin is related to the attenuation in renal oxidative/nitrosative stress induced by cisplatin nephrotoxicity. Free Radic. Res. 43 (2009) 1122-1132
22. Rios A., de O., Antunes L.M.G., Bianchi M., and de L.P. Bixin and lycopene modulation of free radical generation induced by cisplatin-DNA interaction. Food Chem. 113 (2009) 1113-1118
23. Thimmulappa R.K., Mai K.H., Srisuma S., Kensler T.W., Yamamoto M., and Biswal S. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer Res. 62 (2002) 5196-5203
24. Weijl N.I., Elsendoorn T.J., Lentjes E.G., Hopman G.D., Wipkink-Bakker A., Zwinderman A.H., Cleton F.J., and Osanto S. Supplementation with antioxidant micronutrients and chemotherapy-induced toxicity in cancer patients treated with cisplatin-based chemotherapy: a randomised, double-blind, placebo-controlled study. Eur. J. Cancer 40 (2004) 1713-1723
25. Yoon H.Y., Kang N.I., Lee H.K., Jang K.Y., Park J.W., and Park B.H. Sulforaphane protects kidneys against ischemia-reperfusion injury through induction of the Nrf2-dependent phase 2 enzyme. Biochem. Pharmacol. 75 (2008) 2214-2223
26. Zhang D.D. Mechanistic studies of the Nrf2-Keap1 signaling pathway. Drug Metab. Rev. 38 (2006) 769-789