Sulforaphane protects ischemic injury of hearts through antioxidant pathway and mitochondrial KATP channels

Pharmacological Research

Volumn 61, Issue 4, 2010, Pages 342-348

  Piao, Cheng Shi ^a   Gao, Shan ^a   Lee, Geum Hwa ^a   Kim, Do Sung ^a   Park, Byung Hyun ^a   Chae, Soo Wan ^a   Chae, Han Jung ^a   Kim, Suhn Hee ^a  

^a Chonbuk National University Medical School   (South Korea)

Author keywords

Apoptosis; Atrial natriuretic peptide; Bax; Bcl 2; Caspase 3; Catalase; Heart; Heme oxygenase 1; Ischemia; KATP channel; Mitochondria; Sulforaphane; Superoxide dismutase

Indexed keywords

5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ANTIOXIDANT; ATRIAL NATRIURETIC FACTOR; BICARBONATE; CASPASE 3; CATALASE; HEME OXYGENASE 1; LACTATE DEHYDROGENASE; MANGANESE SUPEROXIDE DISMUTASE; PROTEIN BAX; PROTEIN BCL 2; SULFORAPHANE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DRUG MECHANISM; HEART INFARCTION SIZE; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE ISCHEMIA; HEART PERFUSION; HEART PROTECTION; ISOLATED HEART; LACTATE DEHYDROGENASE BLOOD LEVEL; MALE; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIOXIDANTS; ATRIAL NATRIURETIC FACTOR; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; DECANOIC ACIDS; DISEASE MODELS, ANIMAL; DRUG INTERACTIONS; FREE RADICAL SCAVENGERS; HYDROXY ACIDS; KATP CHANNELS; L-LACTATE DEHYDROGENASE; MALE; MITOCHONDRIA; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; POTASSIUM CHANNEL BLOCKERS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; THIOCYANATES;

EID: 77649341955     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2009.11.009     Document Type: Article

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