-
1
-
-
57349126192
-
Behavioral States, Network States, and Sensory Response Variability
-
18614753
-
A Fontanini DB Katz 2008 Behavioral States, Network States, and Sensory Response Variability J Neurophysiol 100 3 1160 1168 18614753
-
(2008)
J Neurophysiol
, vol.100
, Issue.3
, pp. 1160-1168
-
-
Fontanini, A.1
Katz, D.B.2
-
2
-
-
35548940796
-
-
Alzheimer's Association. Alzheimer's Association Washington, D.C.
-
Alzheimer's Association (2009) Alzheimer's Disease Facts and Figures. Alzheimer's Association, Washington, D.C
-
(2009)
Alzheimer's Disease Facts and Figures
-
-
-
3
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
-
E Corder, et al. 1993 Gene Dose of Apolipoprotein E type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families Science 261 5123 921 923 8346443 1:CAS:528:DyaK3sXmtVWjur8%3D (Pubitemid 23275809)
-
(1993)
Science
, vol.261
, Issue.5123
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
4
-
-
0027984085
-
Apolipoprotein e is a Relevant Susceptibility Gene that Affects the Rate of Expression of Alzheimer's disease
-
7700444
-
A Roses 1994 Apolipoprotein E is a Relevant Susceptibility Gene that Affects the Rate of Expression of Alzheimer's disease Neurobiol Aging 15 Suppl 2 S165 S167 7700444
-
(1994)
Neurobiol Aging
, vol.15
, Issue.SUPPL. 2
-
-
Roses, A.1
-
5
-
-
0028856460
-
An English Translation of Alzheimer's 1907 Paper, "Uber Eine Eigenartige Erkankung der Hirnrinde"
-
A Alzheimer R Stelzmann H Schnitzlein F Murtagh 1907 An English Translation of Alzheimer's 1907 Paper, "Uber Eine Eigenartige Erkankung der Hirnrinde" Clin Anat 8 6 429 431
-
(1907)
Clin Anat
, vol.8
, Issue.6
, pp. 429-431
-
-
Alzheimer, A.1
Stelzmann, R.2
Schnitzlein, H.3
Murtagh, F.4
-
6
-
-
0025296269
-
Mutation of the Alzheimer's Disease Amyloid Gene in Hereditary Cerebral Hemorrhage. Dutch Type
-
2111584 1:CAS:528:DyaK3cXkslags7k%3D
-
E Levy, et al. 1990 Mutation of the Alzheimer's Disease Amyloid Gene in Hereditary Cerebral Hemorrhage. Dutch Type Science 248 4959 1124 1126 2111584 1:CAS:528:DyaK3cXkslags7k%3D
-
(1990)
Science
, vol.248
, Issue.4959
, pp. 1124-1126
-
-
Levy, E.1
-
7
-
-
77957927865
-
The Genetics of Alzheimer Disease: Back to the Future
-
20955934 1:CAS:528:DC%2BC3cXhtlSmtr%2FN
-
L Bertram C Lill R Tanzi 2010 The Genetics of Alzheimer Disease: Back to the Future Neuron 68 2 270 281 20955934 1:CAS:528:DC%2BC3cXhtlSmtr%2FN
-
(2010)
Neuron
, vol.68
, Issue.2
, pp. 270-281
-
-
Bertram, L.1
Lill, C.2
Tanzi, R.3
-
8
-
-
0029813255
-
The presenilin genes: A new gene family involved in Alzheimer disease pathology
-
M Cruts L Hendriks C Van Broeckhoven 1996 The presenilin genes: a new gene family involved in Alzheimer disease pathology Hum Mol Genet 5 1449 1455 8875251 1:CAS:528:DyaK28XlsFylur4%3D (Pubitemid 26293907)
-
(1996)
Human Molecular Genetics
, vol.5
, pp. 1449-1455
-
-
Cruts, M.1
Hendriks, L.2
Van Broeckhoven, C.3
-
9
-
-
0029115555
-
The Structure of the Presenilin 1 (S182) Gene and Identification of Six Novel Mutations in Early Onset AD Families
-
1:CAS:528:DyaK2MXosF2rt7g%3D
-
RF Clark, et al. 1995 The Structure of the Presenilin 1 (S182) Gene and Identification of Six Novel Mutations in Early Onset AD Families Nat Genet 11 2 219 222 1:CAS:528:DyaK2MXosF2rt7g%3D
-
(1995)
Nat Genet
, vol.11
, Issue.2
, pp. 219-222
-
-
Clark, R.F.1
-
10
-
-
8944241774
-
Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant
-
DOI 10.1093/hmg/5.7.985
-
R Sherrington, et al. 1996 Alzheimer's Disease Associated with Mutations in Presenilin 2 is Rare and Variably Penetrant Hum Mol Genet 5 7 985 988 8817335 1:CAS:528:DyaK28Xkt1Cnt7s%3D (Pubitemid 26232280)
-
(1996)
Human Molecular Genetics
, vol.5
, Issue.7
, pp. 985-988
-
-
Sherrington, R.1
Froelich, S.2
Sorbi, S.3
Campion, D.4
Chi, H.5
Rogaeva, E.A.6
Levesque, G.7
Rogaev, E.I.8
Lin, C.9
Liang, Y.10
Ikeda, M.11
Mar, L.12
Brice, A.13
Agid, Y.14
Percy, M.E.15
Clerget-Darpoux, F.16
Piacentini, S.17
Marcon, G.18
Nacmias, B.19
Amaducci, L.20
Frebourg, T.21
Lannfelt, L.22
Rommens, J.M.23
St George-Hyslop, P.H.24
more..
-
11
-
-
33749066060
-
Phenotype associated with APP duplication in five families
-
DOI 10.1093/brain/awl237
-
L Cabrejo, et al. 2006 Phenotype Associated with APP Duplication in Five Families Brain 129 11 2966 2976 16959815 (Pubitemid 44684517)
-
(2006)
Brain
, vol.129
, Issue.11
, pp. 2966-2976
-
-
Cabrejo, L.1
Guyant-Marechal, L.2
Laquerriere, A.3
Vercelletto, M.4
De La Fourniere, F.5
Thomas-Anterion, C.6
Verny, C.7
Letournel, F.8
Pasquier, F.9
Vital, A.10
Checler, F.11
Frebourg, T.12
Campion, D.13
Hannequin, D.14
-
12
-
-
29444442794
-
APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy
-
DOI 10.1038/ng1718
-
A Rovelet-Lecrux, et al. 2006 APP Locus Duplication Causes Autosomal Dominant Early-onset Alzheimer Disease with Cerebral Amyloid Angiopathy Nat Genet 38 1 24 26 16369530 1:CAS:528:DC%2BD2MXhtlCmtrzO (Pubitemid 43011878)
-
(2006)
Nature Genetics
, vol.38
, Issue.1
, pp. 24-26
-
-
Rovelet-Lecrux, A.1
Hannequin, D.2
Raux, G.3
Le Meur, N.4
Laquerriere, A.5
Vital, A.6
Dumanchin, C.7
Feuillette, S.8
Brice, A.9
Vercelletto, M.10
Dubas, F.11
Frebourg, T.12
Campion, D.13
-
13
-
-
0025478743
-
Tau Protein and Neurodegeneration
-
2135393 1:CAS:528:DyaK38Xks1Omsb4%3D
-
K Kosik 1990 Tau Protein and Neurodegeneration Mol Neurobiol 4 3 171 179 2135393 1:CAS:528:DyaK38Xks1Omsb4%3D
-
(1990)
Mol Neurobiol
, vol.4
, Issue.3
, pp. 171-179
-
-
Kosik, K.1
-
14
-
-
23444448170
-
Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy
-
DOI 10.1523/JNEUROSCI.1879-05.2005
-
TL Spires, et al. 2005 Dendritic Spine Abnormalities in Amyloid Precursor Protein Transgenic Mice Demonstrated by Gene Transfer and Intravital Multiphoton Microscopy J Neurosci 25 31 7278 7287 16079410 1:CAS:528: DC%2BD2MXnvVWgt7s%3D (Pubitemid 41113944)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.31
, pp. 7278-7287
-
-
Spires, T.L.1
Meyer-Luehmann, M.2
Stern, E.A.3
McLean, P.J.4
Skoch, J.5
Nguyen, P.T.6
Bacskai, B.J.7
Hyman, B.T.8
-
15
-
-
0025863618
-
Neuropathological Stageing of Alzheimer-related Changes
-
1759558 1:STN:280:DyaK387gtFOiug%3D%3D
-
H Braak E Braak 1991 Neuropathological Stageing of Alzheimer-related Changes Acta Neuropathol 82 239 259 1759558 1:STN:280:DyaK387gtFOiug%3D%3D
-
(1991)
Acta Neuropathol
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
16
-
-
0030805991
-
Frequency of stages of Alzheimer-related lesions in different age categories
-
DOI 10.1016/S0197-4580(97)00056-0, PII S0197458097000560
-
H Braak E Braak 1997 Frequency of Stages of Alzheimer-Related Lesions in Different Age Categories Neurobiol Aging 18 4 351 357 9330961 1:STN:280:DyaK2svnt1Sgug%3D%3D (Pubitemid 27435070)
-
(1997)
Neurobiology of Aging
, vol.18
, Issue.4
, pp. 351-357
-
-
Braak, H.1
Braak, E.2
-
17
-
-
0025376092
-
Different Configurational States of Beta-amyloid and their Distributions Relative to Plaques and Tangles in Alzheimer Disease
-
2111023 1:CAS:528:DyaK3cXkt1WksLc%3D
-
MG Spillantini M Goedert R Jakes A Klug 1990 Different Configurational States of Beta-amyloid and their Distributions Relative to Plaques and Tangles in Alzheimer Disease Proc Natl Acad Sci USA 87 10 3947 3951 2111023 1:CAS:528:DyaK3cXkt1WksLc%3D
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, Issue.10
, pp. 3947-3951
-
-
Spillantini, M.G.1
Goedert, M.2
Jakes, R.3
Klug, A.4
-
18
-
-
0021256895
-
Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
-
GG Glenner CW Wong 1984 Alzheimer's Disease: Initial Report of the Purification and Characterization of a Novel Cerebrovascular Amyloid Protein Biochem Biophys Res Commun 120 3 885 890 6375662 1:CAS:528:DyaL2cXitVOntLw%3D (Pubitemid 14104991)
-
(1984)
Biochemical and Biophysical Research Communications
, vol.120
, Issue.3
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
19
-
-
0033595706
-
Beta-secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE
-
10531052 1:CAS:528:DyaK1MXntFWit74%3D
-
R Vassar, et al. 1999 Beta-secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE Science 286 5440 735 741 10531052 1:CAS:528:DyaK1MXntFWit74%3D
-
(1999)
Science
, vol.286
, Issue.5440
, pp. 735-741
-
-
Vassar, R.1
-
20
-
-
0033518251
-
Purification and Cloning of Amyloid Precursor Protein Beta-secretase from Human Brain
-
10591214 1:CAS:528:DyaK1MXotFKlsrc%3D
-
S Sinha, et al. 1999 Purification and Cloning of Amyloid Precursor Protein Beta-secretase from Human Brain Nature 402 6761 537 540 10591214 1:CAS:528:DyaK1MXotFKlsrc%3D
-
(1999)
Nature
, vol.402
, Issue.6761
, pp. 537-540
-
-
Sinha, S.1
-
21
-
-
0033518264
-
Membrane-anchored Aspartyl Protease with Alzheimer's Disease Beta-secretase Activity
-
10591213 1:CAS:528:DyaK1MXotFKmu7k%3D
-
R Yan, et al. 1999 Membrane-anchored Aspartyl Protease with Alzheimer's Disease Beta-secretase Activity Nature 402 6761 533 537 10591213 1:CAS:528:DyaK1MXotFKmu7k%3D
-
(1999)
Nature
, vol.402
, Issue.6761
, pp. 533-537
-
-
Yan, R.1
-
22
-
-
0033382226
-
Identification of a novel aspartic protease (Asp 2) as β-secretase
-
DOI 10.1006/mcne.1999.0811
-
I Hussain, et al. 1999 Identification of a Novel Aspartic Protease (Asp 2) as Beta-secretase Mol Cell Neurosci 14 6 419 427 10656250 1:CAS:528:DyaK1MXnt1Chsrs%3D (Pubitemid 30026585)
-
(1999)
Molecular and Cellular Neurosciences
, vol.14
, Issue.6
, pp. 419-427
-
-
Hussain, I.1
Powell, D.2
Howlett, D.R.3
Tew, D.G.4
Meek, T.D.5
Chapman, C.6
Gloger, I.S.7
Murphy, K.E.8
Southan, C.D.9
Ryan, D.M.10
Smith, T.S.11
Simmons, D.L.12
Walsh, F.S.13
Dingwall, C.14
Christie, G.15
-
23
-
-
10744229989
-
Neurochemical diagnosis of Alzheimer's dementia by CSF Aβ42, Aβ42/Aβ40 ratio and total tau
-
DOI 10.1016/S0197-4580(03)00086-1
-
P Lewczuk, et al. 2004 Neurochemical Diagnosis of Alzheimer's Dementia by CSF Abeta42, Abeta42/Abeta40 Ratio and Total Tau Neurobiol Aging 25 3 273 281 15123331 1:CAS:528:DC%2BD2cXhtV2ksLY%3D (Pubitemid 38220961)
-
(2004)
Neurobiology of Aging
, vol.25
, Issue.3
, pp. 273-281
-
-
Lewczuk, P.1
Esselmann, H.2
Otto, M.3
Maler, J.M.4
Henkel, A.W.5
Henkel, M.K.6
Eikenberg, O.7
Antz, C.8
Krause, W.-R.9
Reulbach, U.10
Kornhuber, J.11
Wiltfang, J.12
-
24
-
-
0030293676
-
Familial Alzheimer's disease-linked presenilin I variants elevate aβ1- 42/1-40 ratio in vitro and in vivo
-
DOI 10.1016/S0896-6273(00)80230-5
-
DR Borchelt, et al. 1996 Familial Alzheimer's Disease-Linked Presenilin 1 Variants Elevate A[beta]1-42/1-40 Ratio In Vitro and In Vivo Neuron 17 5 1005 1013 8938131 1:CAS:528:DyaK28XnsVCrtL0%3D (Pubitemid 26424026)
-
(1996)
Neuron
, vol.17
, Issue.5
, pp. 1005-1013
-
-
Borchelt, D.R.1
Thinakaran, G.2
Eckman, C.B.3
Lee, M.K.4
Davenport, F.5
Ratovitsky, T.6
Prada, C.-M.7
Kim, G.8
Seekins, S.9
Yager, D.10
Slunt, H.H.11
Wang, R.12
Seeger, M.13
Levey, A.I.14
Gandy, S.E.15
Copeland, N.G.16
Jenkins, N.A.17
Price, D.L.18
Younkin, S.G.19
Sisodia, S.S.20
more..
-
25
-
-
77957785420
-
Neurotoxicity of Alzheimer's Disease Aβ Peptides is Induced by Small Changes in the Aβ42 to Aβ40 ratio
-
20818335 1:CAS:528:DC%2BC3cXhtFSmsbzP
-
I Kuperstein, et al. 2010 Neurotoxicity of Alzheimer's Disease Aβ Peptides is Induced by Small Changes in the Aβ42 to Aβ40 ratio EMBO J 29 19 3408 3420 20818335 1:CAS:528:DC%2BC3cXhtFSmsbzP
-
(2010)
EMBO J
, vol.29
, Issue.19
, pp. 3408-3420
-
-
Kuperstein, I.1
-
26
-
-
77957782470
-
Biology of Amyloid: Structure, Function, and Regulation
-
20947013 1:CAS:528:DC%2BC3cXhtlSntbbP
-
J Greenwald R Riek 2010 Biology of Amyloid: Structure, Function, and Regulation Structure 18 10 1244 1260 20947013 1:CAS:528:DC%2BC3cXhtlSntbbP
-
(2010)
Structure
, vol.18
, Issue.10
, pp. 1244-1260
-
-
Greenwald, J.1
Riek, R.2
-
27
-
-
0344672942
-
APP Processing and Synaptic Function
-
DOI 10.1016/S0896-6273(03)00124-7
-
F Kamenetz, et al. 2003 APP Processing and Synaptic Function Neuron 37 6 925 937 12670422 1:CAS:528:DC%2BD3sXivFWkurY%3D (Pubitemid 36398299)
-
(2003)
Neuron
, vol.37
, Issue.6
, pp. 925-937
-
-
Kamenetz, F.1
Tomita, T.2
Hsieh, H.3
Seabrook, G.4
Borchelt, D.5
Iwatsubo, T.6
Sisodia, S.7
Malinow, R.8
-
28
-
-
41549155927
-
Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-β In Vivo
-
DOI 10.1016/j.neuron.2008.02.003, PII S0896627308001244
-
JR Cirrito, et al. 2008 Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-[beta] In Vivo Neuron 58 1 42 51 18400162 1:CAS:528:DC%2BD1cXltVOisrc%3D (Pubitemid 351467029)
-
(2008)
Neuron
, vol.58
, Issue.1
, pp. 42-51
-
-
Cirrito, J.R.1
Kang, J.-E.2
Lee, J.3
Stewart, F.R.4
Verges, D.K.5
Silverio, L.M.6
Bu, G.7
Mennerick, S.8
Holtzman, D.M.9
-
29
-
-
29144487182
-
Synaptic activity regulates interstitial fluid amyloid-β levels in vivo
-
DOI 10.1016/j.neuron.2005.10.028, PII S0896627305009396
-
JR Cirrito, et al. 2005 Synaptic Activity Regulates Interstitial Fluid Amyloid-[beta] Levels In Vivo Neuron 48 6 913 922 16364896 1:CAS:528: DC%2BD28XivFSksg%3D%3D (Pubitemid 41814696)
-
(2005)
Neuron
, vol.48
, Issue.6
, pp. 913-922
-
-
Cirrito, J.R.1
Yamada, K.A.2
Finn, M.B.3
Sloviter, R.S.4
Bales, K.R.5
May, P.C.6
Schoepp, D.D.7
Paul, S.M.8
Mennerick, S.9
Holtzman, D.M.10
-
30
-
-
34250819839
-
Intracellular Amyloid-[beta] in Alzheimer's Disease
-
17551515 1:CAS:528:DC%2BD2sXmslWjsr8%3D
-
FM LaFerla KN Green S Oddo 2007 Intracellular Amyloid-[beta] in Alzheimer's Disease Nat Rev Neurosci 8 7 499 509 17551515 1:CAS:528: DC%2BD2sXmslWjsr8%3D
-
(2007)
Nat Rev Neurosci
, vol.8
, Issue.7
, pp. 499-509
-
-
Laferla, F.M.1
Green, K.N.2
Oddo, S.3
-
31
-
-
70450235497
-
Alzheimer's Disease-like Pathological Features in Transgenic Mice Expressing the APP Intracellular Domain
-
19837693 1:CAS:528:DC%2BD1MXhsVWrtr3N
-
K Ghosal, et al. 2009 Alzheimer's Disease-like Pathological Features in Transgenic Mice Expressing the APP Intracellular Domain Proc Natl Acad Sci 106 43 18367 18372 19837693 1:CAS:528:DC%2BD1MXhsVWrtr3N
-
(2009)
Proc Natl Acad Sci
, vol.106
, Issue.43
, pp. 18367-18372
-
-
Ghosal, K.1
-
32
-
-
76549096350
-
Alzheimers-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition
-
20080541 1:CAS:528:DC%2BC3cXhslGgt74%3D
-
Y Jiang, et al. 2010 Alzheimers-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition Proc Natl Acad Sci 107 4 1630 1635 20080541 1:CAS:528: DC%2BC3cXhslGgt74%3D
-
(2010)
Proc Natl Acad Sci
, vol.107
, Issue.4
, pp. 1630-1635
-
-
Jiang, Y.1
-
33
-
-
0031921466
-
Mutant genes in familial Alzheimer's disease and transgenic models
-
DOI 10.1146/annurev.neuro.21.1.479
-
DL Price SS Sisodia 1998 Mutant Genes in Familial Alzheimer's Disease and Transgenic Models Annu Rev Neurosci 21 1 479 505 9530504 1:CAS:528: DyaK1cXhsFyhtLY%3D (Pubitemid 28150671)
-
(1998)
Annual Review of Neuroscience
, vol.21
, pp. 479-505
-
-
Price, D.L.1
Sisodia, S.S.2
-
35
-
-
25644461150
-
Acute γ-secretase inhibition improves contextual fear conditioning in the Tg2576 mouse model of Alzheimer's disease
-
DOI 10.1523/JNEUROSCI.2693-05.2005
-
TA Comery, et al. 2005 Acute {gamma}-Secretase Inhibition Improves Contextual Fear Conditioning in the Tg2576 Mouse Model of Alzheimer's Disease J Neurosci 25 39 8898 8902 16192379 1:CAS:528:DC%2BD2MXhtVOqs7rE (Pubitemid 41384457)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.39
, pp. 8898-8902
-
-
Comery, T.A.1
Martone, R.L.2
Aschmies, S.3
Atchison, K.P.4
Diamantidis, G.5
Gong, X.6
Zhou, H.7
Kreft, A.F.8
Pangalos, M.N.9
Sonnenberg-Reines, J.10
Jacobsen, J.S.11
Marquis, K.L.12
-
36
-
-
0038476561
-
The γ-secretase inhibitor N-[N-(3,5-difluorophenacetyl)-lalanyl]-S- phenylglycine t-butyl ester reduces Aβ levels in vivo in plasma and cerebrospinal fluid in young (plaque-free) and aged (plaque-bearing) Tg2576 mice
-
DOI 10.1124/jpet.102.048280
-
TA Lanz, et al. 2003 The gamma-Secretase Inhibitor N-[N-(3,5- Difluorophenacetyl)-l-alanyl]-S-phenylglycine t-butyl Ester Reduces Abeta Levels in Vivo in Plasma and Cerebrospinal Fluid in Young (Plaque-Free) and Aged (Plaque-Bearing) Tg2576 Mice J Pharmacol Exp Ther 305 3 864 871 12626636 1:CAS:528:DC%2BD3sXkt1Sns7c%3D (Pubitemid 36617962)
-
(2003)
Journal of Pharmacology and Experimental Therapeutics
, vol.305
, Issue.3
, pp. 864-871
-
-
Lanz, T.A.1
Himes, C.S.2
Pallante, G.3
Adams, L.4
Yamazaki, S.5
Amore, B.6
Merchant, K.M.7
-
37
-
-
77956311201
-
Modulation of Gamma-secretase Reduces Beta-amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease
-
20826309 1:CAS:528:DC%2BC3cXhtFamtb%2FI
-
M Kounnas, et al. 2010 Modulation of Gamma-secretase Reduces Beta-amyloid Deposition in a Transgenic Mouse Model of Alzheimer's Disease Neuron 67 5 769 780 20826309 1:CAS:528:DC%2BC3cXhtFamtb%2FI
-
(2010)
Neuron
, vol.67
, Issue.5
, pp. 769-780
-
-
Kounnas, M.1
-
38
-
-
77957361080
-
Alzheimer's Failure Raises Questions about Disease-modifying Strategies
-
20885394 1:CAS:528:DC%2BC3cXht1akur7J
-
A Extance 2010 Alzheimer's Failure Raises Questions about Disease-modifying Strategies Nat Rev Drug Discov 9 10 749 751 20885394 1:CAS:528:DC%2BC3cXht1akur7J
-
(2010)
Nat Rev Drug Discov
, vol.9
, Issue.10
, pp. 749-751
-
-
Extance, A.1
-
39
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
DOI 10.1126/science.1072994
-
J Hardy DJ Selkoe 2002 The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics Science 297 5580 353 356 12130773 1:CAS:528:DC%2BD38Xls1Cju7s%3D (Pubitemid 34790756)
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
40
-
-
67650875899
-
Amyloid Deposition is Associated with Impaired Default Network Function in Older Persons without Dementia
-
19640477 1:CAS:528:DC%2BD1MXhsVCiurjM
-
R Sperling, et al. 2009 Amyloid Deposition is Associated with Impaired Default Network Function in Older Persons without Dementia Neuron 63 2 178 188 19640477 1:CAS:528:DC%2BD1MXhsVCiurjM
-
(2009)
Neuron
, vol.63
, Issue.2
, pp. 178-188
-
-
Sperling, R.1
-
41
-
-
70350266228
-
Amyloid Imaging in Aging and Dementia: Testing the Amyloid Hypothesis in vivo
-
19847050 1:STN:280:DC%2BD1Mjgslersw%3D%3D
-
GD Rabinovici WJ Jagust 2009 Amyloid Imaging in Aging and Dementia: Testing the Amyloid Hypothesis in vivo Behav Neurol 21 1 117 128 19847050 1:STN:280:DC%2BD1Mjgslersw%3D%3D
-
(2009)
Behav Neurol
, vol.21
, Issue.1
, pp. 117-128
-
-
Rabinovici, G.D.1
Jagust, W.J.2
-
42
-
-
55949117032
-
Frequent Amyloid Deposition Without Significant Cognitive Impairment among the Elderly
-
19001171
-
HJ Aizenstein, et al. 2008 Frequent Amyloid Deposition Without Significant Cognitive Impairment Among the Elderly Arch Neurol 65 11 1509 1517 19001171
-
(2008)
Arch Neurol
, vol.65
, Issue.11
, pp. 1509-1517
-
-
Aizenstein, H.J.1
-
43
-
-
34248560960
-
Amyloid-β in Alzheimer disease: The null versus the alternate hypotheses
-
DOI 10.1124/jpet.106.114009
-
H-G Lee, et al. 2007 Amyloid-B in Alzheimer Disease: The Null versus the Alternate Hypotheses J Pharmacol Exp Ther 321 3 823 829 17229880 1:CAS:528:DC%2BD2sXmsFerurk%3D (Pubitemid 46762675)
-
(2007)
Journal of Pharmacology and Experimental Therapeutics
, vol.321
, Issue.3
, pp. 823-829
-
-
Lee, H.-G.1
Zhu, X.2
Castellani, R.J.3
Nunomura, A.4
Perry, G.5
Smith, M.A.6
-
44
-
-
0008538685
-
A Protein Factor Essential for Microtubule Assembly
-
1057175 1:CAS:528:DyaE2MXkt1ersbw%3D
-
MD Weingarten AH Lockwood SY Hwo MW Kirschner 1975 A Protein Factor Essential for Microtubule Assembly Proc Natl Acad Sci USA 72 5 1858 1862 1057175 1:CAS:528:DyaE2MXkt1ersbw%3D
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, Issue.5
, pp. 1858-1862
-
-
Weingarten, M.D.1
Lockwood, A.H.2
Hwo, S.Y.3
Kirschner, M.W.4
-
45
-
-
0028491607
-
Mechanism of Neurofibrillary Degeneration in Alzheimer's Disease
-
7888088 1:STN:280:DyaK2M7psVGrsQ%3D%3D
-
K Iqbal, et al. 1994 Mechanism of Neurofibrillary Degeneration in Alzheimer's Disease Mol Neurobiol 9 1-3 119 123 7888088 1:STN:280: DyaK2M7psVGrsQ%3D%3D
-
(1994)
Mol Neurobiol
, vol.9
, Issue.13
, pp. 119-123
-
-
Iqbal, K.1
-
47
-
-
0025770134
-
The Distribution of Tangles, Plaques and Related immunohistochemical Markers in Healthy Aging and Alzheimer's Disease
-
1961359 1:STN:280:DyaK38%2Fnt1ygtQ%3D%3D
-
J Price P Davis J Morris D White 1991 The Distribution of Tangles, Plaques and Related immunohistochemical Markers in Healthy Aging and Alzheimer's Disease Neurobiol Aging 12 4 295 312 1961359 1:STN:280:DyaK38%2Fnt1ygtQ%3D%3D
-
(1991)
Neurobiol Aging
, vol.12
, Issue.4
, pp. 295-312
-
-
Price, J.1
Davis, P.2
Morris, J.3
White, D.4
-
48
-
-
0031935017
-
Vulnerable neuronal subsets in Alzheimer's and Pick's disease are distinguished by their τ isoform distribution and phosphorylation
-
DOI 10.1002/ana.410430209
-
A Delacourte N Sergeant A Wattez D Gauvreau Y Robitaille 1998 Vulnerable Neuronal Subsets in Alzheimer's and Pick's Disease are Distinguished by their Tau Isoform Distribution and Phosphorylation Ann Neurol 43 2 193 204 9485060 1:STN:280:DyaK1c7ktlGqtg%3D%3D (Pubitemid 28110121)
-
(1998)
Annals of Neurology
, vol.43
, Issue.2
, pp. 193-204
-
-
Delacourte, A.1
Sergeant, N.2
Wattez, A.3
Gauvreau, D.4
Robitaille, Y.5
-
49
-
-
0028965635
-
Somatodendritic Localization and Hyperphosphorylation of Tau Protein in Transgenic Mice Expressing the Longest Human Brain Tau Isoform
-
7729409 1:STN:280:DyaK2M3ks1OhsQ%3D%3D
-
J Gotz, et al. 1995 Somatodendritic Localization and Hyperphosphorylation of Tau Protein in Transgenic Mice Expressing the Longest Human Brain Tau Isoform EMBO J 14 7 1304 1313 7729409 1:STN:280:DyaK2M3ks1OhsQ%3D%3D
-
(1995)
EMBO J
, vol.14
, Issue.7
, pp. 1304-1313
-
-
Gotz, J.1
-
50
-
-
17944382037
-
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
-
DOI 10.1126/science.1058189
-
J Lewis, et al. 2001 Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP Science 293 5534 1487 1491 11520987 1:CAS:528:DC%2BD3MXmsVeru7Y%3D (Pubitemid 32801551)
-
(2001)
Science
, vol.293
, Issue.5534
, pp. 1487-1491
-
-
Lewis, J.1
Dickson, D.W.2
Lin, W.-L.3
Chisholm, L.4
Corral, A.5
Jones, G.6
Yen, S.-H.7
Sahara, N.8
Skipper, L.9
Yager, D.10
Eckman, C.11
Hardy, J.12
Hutton, M.13
McGowan, E.14
-
51
-
-
0035943436
-
Formation of neurofibrillary tangles in P301L tau transgenic mice induced by Aβ42 fibrils
-
DOI 10.1126/science.1062097
-
J Gotz F Chen J van Dorpe RM Nitsch 2001 Formation of Neurofibrillary Tangles in P301L Tau Transgenic Mice Induced by Abeta 42 Fibrils Science 293 5534 1491 1495 11520988 1:STN:280:DC%2BD3MvnslKjsA%3D%3D (Pubitemid 32807681)
-
(2001)
Science
, vol.293
, Issue.5534
, pp. 1491-1495
-
-
Gotz, J.1
Chen, F.2
Van Dorpe, J.3
Nitsch, R.M.4
-
52
-
-
4043167747
-
Aβ immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
-
DOI 10.1016/j.neuron.2004.07.003, PII S0896627304004246
-
S Oddo L Billings JP Kesslak D Cribbs F LaFerla 2004 Abeta Immunotherapy Leads to Clearance of Early, but not late, Hyperphosphorylated Tau Aggregates via the Proteasome Neuron 43 3 321 332 15294141 1:CAS:528:DC%2BD2cXmvFOisLk%3D (Pubitemid 39061125)
-
(2004)
Neuron
, vol.43
, Issue.3
, pp. 321-332
-
-
Oddo, S.1
Billings, L.2
Kesslak, J.P.3
Cribbs, D.H.4
LaFerla, F.M.5
-
53
-
-
34248181511
-
Reducing endogenous tau ameliorates amyloid β-induced deficits in an Alzheimer's disease mouse model
-
DOI 10.1126/science.1141736
-
ED Roberson, et al. 2007 Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model Science 316 5825 750 754 17478722 1:CAS:528:DC%2BD2sXkvVWrtrw%3D (Pubitemid 46717684)
-
(2007)
Science
, vol.316
, Issue.5825
, pp. 750-754
-
-
Roberson, E.D.1
Scearce-Levie, K.2
Palop, J.J.3
Yan, F.4
Cheng, I.H.5
Wu, T.6
Gerstein, H.7
Yu, G.-Q.8
Mucke, L.9
-
54
-
-
77957737750
-
Tau Reduction Prevents Abeta-induced Defects in Axonal Transport
-
20829454 1:CAS:528:DC%2BC3cXht1CgtrfN
-
K Vossel, et al. 2010 Tau Reduction Prevents Abeta-induced Defects in Axonal Transport Science 330 6001 198 198 20829454 1:CAS:528:DC%2BC3cXht1CgtrfN
-
(2010)
Science
, vol.330
, Issue.6001
, pp. 198-198
-
-
Vossel, K.1
-
55
-
-
78650251838
-
Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration
-
21172610 1:CAS:528:DC%2BC3cXhsFykt7vO
-
B Hoover, et al. 2010 Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration Neuron 68 6 1067 1081 21172610 1:CAS:528:DC%2BC3cXhsFykt7vO
-
(2010)
Neuron
, vol.68
, Issue.6
, pp. 1067-1081
-
-
Hoover, B.1
-
56
-
-
0033869715
-
Endocytic pathway abnormalities precede amyloid β deposition in sporadic alzheimer's disease and down syndrome: Differential effects of APOE genotype and presenilin mutations
-
AM Cataldo, et al. 2000 Endocytic Pathway Abnormalities Precede Amyloid beta Deposition in Sporadic Alzheimer's Disease and Down Syndrome : Differential Effects of APOE Genotype and Presenilin Mutations Am J Pathol 157 1 277 286 10880397 1:CAS:528:DC%2BD3cXlsVGmtLw%3D (Pubitemid 30641743)
-
(2000)
American Journal of Pathology
, vol.157
, Issue.1
, pp. 277-286
-
-
Cataldo, A.M.1
Peterhoff, C.M.2
Troncoso, J.C.3
Gomez-Isla, T.4
Hyman, B.T.5
Nixon, R.A.6
-
57
-
-
78650803250
-
Regional Selectivity of rab5 and rab7 Protein Upregulation in Mild Cognitive Impairment and Alzheimer's Disease
-
20847427 1:CAS:528:DC%2BC3cXhsVektLjK
-
SD Ginsberg, et al. 2010 Regional Selectivity of rab5 and rab7 Protein Upregulation in Mild Cognitive Impairment and Alzheimer's Disease J Alzheimers Dis 22 2 631 639 20847427 1:CAS:528:DC%2BC3cXhsVektLjK
-
(2010)
J Alzheimers Dis
, vol.22
, Issue.2
, pp. 631-639
-
-
Ginsberg, S.D.1
-
58
-
-
0041632362
-
App gene dosage modulates endosomal abnormalities of Alzheimer's disease in a segmental trisomy 16 mouse model of Down syndrome
-
AM Cataldo, et al. 2003 App Gene Dosage Modulates Endosomal Abnormalities of Alzheimer's Disease in a Segmental Trisomy 16 Mouse Model of Down Syndrome J Neurosci 23 17 6788 6792 12890772 1:CAS:528:DC%2BD3sXmtFentrk%3D (Pubitemid 36951206)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.17
, pp. 6788-6792
-
-
Cataldo, A.M.1
Petanceska, S.2
Peterhoff, C.M.3
Terio, N.B.4
Epstein, C.J.5
Villar, A.6
Carlson, E.J.7
Staufenbiel, M.8
Nixon, R.A.9
-
59
-
-
33745512851
-
Increased App Expression in a Mouse Model of Down's Syndrome Disrupts NGF Transport and Causes Cholinergic Neuron Degeneration
-
DOI 10.1016/j.neuron.2006.05.022, PII S0896627306004144
-
A Salehi, et al. 2006 Increased App Expression in a Mouse Model of Down's Syndrome Disrupts NGF Transport and Causes Cholinergic Neuron Degeneration Neuron 51 1 29 42 16815330 1:CAS:528:DC%2BD28XnsVWgsrY%3D (Pubitemid 43963336)
-
(2006)
Neuron
, vol.51
, Issue.1
, pp. 29-42
-
-
Salehi, A.1
Delcroix, J.-D.2
Belichenko, P.V.3
Zhan, K.4
Wu, C.5
Valletta, J.S.6
Takimoto-Kimura, R.7
Kleschevnikov, A.M.8
Sambamurti, K.9
Chung, P.P.10
Xia, W.11
Villar, A.12
Campbell, W.A.13
Kulnane, L.S.14
Nixon, R.A.15
Lamb, B.T.16
Epstein, C.J.17
Stokin, G.B.18
Goldstein, L.S.B.19
Mobley, W.C.20
more..
-
60
-
-
48249103491
-
Neurodegenerative Lysosomal Disorders: A Continuum from Development to Late Age
-
18497567 1:CAS:528:DC%2BD1cXpsVCktrg%3D
-
RA Nixon D-S Yang J-H Lee 2008 Neurodegenerative Lysosomal Disorders: A Continuum from Development to Late Age Autophagy 4 5 590 599 18497567 1:CAS:528:DC%2BD1cXpsVCktrg%3D
-
(2008)
Autophagy
, vol.4
, Issue.5
, pp. 590-599
-
-
Nixon, R.A.1
Yang, D.-S.2
Lee, J.-H.3
-
61
-
-
78149488153
-
Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis
-
21068297 1:CAS:528:DC%2BC3cXhsV2nurvP
-
SW Pimplikar RA Nixon NK Robakis J Shen L-H Tsai 2010 Amyloid-Independent Mechanisms in Alzheimer's Disease Pathogenesis J Neurosci 30 45 14946 14954 21068297 1:CAS:528:DC%2BC3cXhsV2nurvP
-
(2010)
J Neurosci
, vol.30
, Issue.45
, pp. 14946-14954
-
-
Pimplikar, S.W.1
Nixon, R.A.2
Robakis, N.K.3
Shen, J.4
Tsai, L.-H.5
-
62
-
-
33748524564
-
Antiamyloidogenic and Neuroprotective Functions of Cathepsin B: Implications for Alzheimer's Disease
-
DOI 10.1016/j.neuron.2006.07.027, PII S0896627306005976
-
S Mueller-Steiner, et al. 2006 Antiamyloidogenic and Neuroprotective Functions of Cathepsin B: Implications for Alzheimer's Disease Neuron 51 6 703 714 16982417 1:CAS:528:DC%2BD28XhtVGls7%2FK (Pubitemid 44374903)
-
(2006)
Neuron
, vol.51
, Issue.6
, pp. 703-714
-
-
Mueller-Steiner, S.1
Zhou, Y.2
Arai, H.3
Roberson, E.D.4
Sun, B.5
Chen, J.6
Wang, X.7
Yu, G.8
Esposito, L.9
Mucke, L.10
Gan, L.11
-
63
-
-
78650716872
-
Reversal of Autophagy Dysfunction in the TgCRND8 Mouse Model of Alzheimer's Disease Ameliorates Amyloid Pathologies and Memory Deficits
-
21186265
-
DS Yang, et al. 2011 Reversal of Autophagy Dysfunction in the TgCRND8 Mouse Model of Alzheimer's Disease Ameliorates Amyloid Pathologies and Memory Deficits Brain 134 Pt 1 258 277 21186265
-
(2011)
Brain
, vol.134
, Issue.PART 1
, pp. 258-277
-
-
Yang, D.S.1
-
64
-
-
0035875690
-
Increased lipid peroxidation precedes amyloid plaque formation in an animal model of alzheimer amyloidosis
-
D Pratico K Uryu S Leight JQ Trojanoswki VMY Lee 2001 Increased Lipid Peroxidation Precedes Amyloid Plaque Formation in an Animal Model of Alzheimer Amyloidosis J Neurosci 21 12 4183 4187 11404403 1:CAS:528:DC%2BD3MXktlKls74%3D (Pubitemid 32538543)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.12
, pp. 4183-4187
-
-
Pratico, D.1
Uryu, K.2
Leight, S.3
Trojanoswki, J.Q.4
Lee, V.M.-Y.5
-
65
-
-
0041921071
-
Anti-inflammatory drug therapy alters β-amyloid processing and deposition in an animal model of Alzheimer's disease
-
Q Yan, et al. 2003 Anti-inflammatory Drug Therapy Alters Beta-amyloid Processing and Deposition in an Animal Model of Alzheimer's Disease J Neurosci 23 20 7504 7509 12930788 1:CAS:528:DC%2BD3sXmvFaisLg%3D (Pubitemid 37034066)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.20
, pp. 7504-7509
-
-
Yan, Q.1
Zhang, J.2
Liu, H.3
Babu-Khan, S.4
Vassar, R.5
Biere, A.L.6
Citron, M.7
Landreth, G.8
-
66
-
-
75949127362
-
Inflammation, Microglia, and Alzheimer's Disease
-
19833208 1:CAS:528:DC%2BC3cXitV2ktb8%3D
-
B Cameron GE Landreth 2010 Inflammation, Microglia, and Alzheimer's Disease Neurobiol Dis 37 3 503 509 19833208 1:CAS:528:DC%2BC3cXitV2ktb8%3D
-
(2010)
Neurobiol Dis
, vol.37
, Issue.3
, pp. 503-509
-
-
Cameron, B.1
Landreth, G.E.2
-
68
-
-
0031020476
-
A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid β- peptide
-
RJ Mark MA Lovell WR Markesbery K Uchida MP Mattson 1997 A Role for 4-hydroxynonenal, an Aldehydic Product of Lipid Peroxidation, in Disruption of Ion Homeostasis and Neuronal Death Induced by Amyloid Beta-peptide J Neurochem 68 1 255 264 8978733 1:CAS:528:DyaK2sXhsFyltA%3D%3D (Pubitemid 26427315)
-
(1997)
Journal of Neurochemistry
, vol.68
, Issue.1
, pp. 255-264
-
-
Mark, R.J.1
Lovell, M.A.2
Markesbery, W.R.3
Uchida, K.4
Mattson, M.P.5
-
69
-
-
57649221161
-
Evidence of Oxidative Stress in Alzheimer's Disease Brain and Antioxidant therapy: Lights and Shadows
-
19076432 1:CAS:528:DC%2BD1MXhsVaqtb0%3D
-
D Pratico 2008 Evidence of Oxidative Stress in Alzheimer's Disease Brain and Antioxidant therapy: Lights and Shadows Ann NY Acad Sci 1147 70 78 19076432 1:CAS:528:DC%2BD1MXhsVaqtb0%3D
-
(2008)
Ann NY Acad Sci
, vol.1147
, pp. 70-78
-
-
Pratico, D.1
-
70
-
-
78650403081
-
Reimagining Alzheimer's Disease-An Age-Based Hypothesis
-
21159946 1:CAS:528:DC%2BC3cXhs1Slsb3N
-
K Herrup 2010 Reimagining Alzheimer's Disease-An Age-Based Hypothesis J Neurosci 30 50 16755 16762 21159946 1:CAS:528:DC%2BC3cXhs1Slsb3N
-
(2010)
J Neurosci
, vol.30
, Issue.50
, pp. 16755-16762
-
-
Herrup, K.1
-
71
-
-
79951624773
-
Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's disease
-
in press
-
Wilkinson BL et al. (2010) Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's disease. Neurobiol Aging, in press
-
Neurobiol Aging
, pp. 2010
-
-
Wilkinson, B.L.1
-
72
-
-
77954865635
-
Systemic Inflammatory Cells Fight off Neurodegenerative Disease. Nature Reviews
-
20531383 1:CAS:528:DC%2BC3cXovFKgt7c%3D
-
M Schwartz R Shechter 2010 Systemic Inflammatory Cells Fight Off Neurodegenerative Disease. Nature Reviews Neurology 6 7 405 410 20531383 1:CAS:528:DC%2BC3cXovFKgt7c%3D
-
(2010)
Neurology
, vol.6
, Issue.7
, pp. 405-410
-
-
Schwartz, M.1
Shechter, R.2
-
73
-
-
0029021217
-
Do Nonsteroidal Anti-inflammatory Drugs Decrease the Risk for Alzheimer's Disease? the Rotterdam Study
-
7644037 1:CAS:528:DyaK2MXns1Sis78%3D
-
K Andersen, et al. 1995 Do Nonsteroidal Anti-inflammatory Drugs Decrease the Risk for Alzheimer's Disease? The Rotterdam Study Neurology 45 8 1441 1445 7644037 1:CAS:528:DyaK2MXns1Sis78%3D
-
(1995)
Neurology
, vol.45
, Issue.8
, pp. 1441-1445
-
-
Andersen, K.1
-
76
-
-
0015799240
-
Long-lasting Potentiation of Synaptic Transmission in the Dentate Area of the Anaesthetized Rabbit Following Stimulation of the Perforant Path
-
4727084 1:STN:280:DyaE3s3ktlersw%3D%3D
-
TVP Bliss T Lomo 1973 Long-lasting Potentiation of Synaptic Transmission in the Dentate Area of the Anaesthetized Rabbit Following Stimulation of the Perforant Path J Physiol 232 2 331 356 4727084 1:STN:280:DyaE3s3ktlersw%3D%3D
-
(1973)
J Physiol
, vol.232
, Issue.2
, pp. 331-356
-
-
Bliss, T.V.P.1
Lomo, T.2
-
77
-
-
20444410827
-
Plasticity of dendritic function
-
DOI 10.1016/j.conb.2005.05.013, PII S0959438805000784
-
J Magee D Johnston 2005 Plasticity of dendritic function Curr Opin Neurobiol 15 3 334 342 15922583 1:CAS:528:DC%2BD2MXlt1SrsrY%3D (Pubitemid 40806446)
-
(2005)
Current Opinion in Neurobiology
, vol.15
, Issue.3 SPEC. ISS.
, pp. 334-342
-
-
Magee, J.C.1
Johnston, D.2
-
78
-
-
0020647470
-
Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampus
-
GL Collingridge SJ Kehl H McLennan 1983 Excitatory Amino Acids in Synaptic Transmission in the Schaffer Collateral-commissural Pathway of the Rat Hippocampus J Physiol 334 1 33 46 6306230 1:CAS:528:DyaL38XmtV2itLw%3D (Pubitemid 13176081)
-
(1983)
Journal of Physiology
, vol.334
, pp. 33-46
-
-
Collingridge, G.L.1
Kehl, S.J.2
McLennan, H.3
-
79
-
-
0020507947
-
Intracellular injections of EGTA block induction of hippocampal long-term potentiation
-
G Lynch J Larson S Kelso G Barrionuevo F Schottler 1983 Intracellular Injections of EGTA Block Induction of Hippocampal Long-term Potentiation Nature 305 5936 719 721 6415483 1:CAS:528:DyaL3sXmtFSmsLw%3D (Pubitemid 13021524)
-
(1983)
Nature
, vol.305
, Issue.5936
, pp. 719-721
-
-
Lynch, G.1
Larson, J.2
Kelso, S.3
-
80
-
-
0033681557
-
Regulation of AMPA Receptor-mediated Synaptic Transmission by Clathrin-dependent Receptor Internalization
-
10774732 1:CAS:528:DC%2BD3cXisFKrtb0%3D
-
HY Man, et al. 2000 Regulation of AMPA Receptor-mediated Synaptic Transmission by Clathrin-dependent Receptor Internalization Neuron 25 3 649 662 10774732 1:CAS:528:DC%2BD3cXisFKrtb0%3D
-
(2000)
Neuron
, vol.25
, Issue.3
, pp. 649-662
-
-
Man, H.Y.1
-
81
-
-
0034865774
-
Long-term depression: A cascade of induction and expression mechanisms
-
DOI 10.1016/S0301-0082(01)00013-2, PII S0301008201000132
-
N Kemp ZI Bashir 2001 Long-term Depression: A Cascade of Induction and Expression Mechanisms Prog Neurobiol 65 4 339 365 11527572 1:STN:280: DC%2BD3Mvos1ahtQ%3D%3D (Pubitemid 32781668)
-
(2001)
Progress in Neurobiology
, vol.65
, Issue.4
, pp. 339-365
-
-
Kemp, N.1
Bashir, Z.I.2
-
82
-
-
41349096492
-
Compartmentalized dendritic plasticity and input feature storage in neurons
-
DOI 10.1038/nature06725, PII NATURE06725
-
A Losonczy JK Makara JC Magee 2008 Compartmentalized Dendritic Plasticity and Input Feature Storage in Neurons Nature 452 436 441 18368112 1:CAS:528:DC%2BD1cXjslCnuro%3D (Pubitemid 351450839)
-
(2008)
Nature
, vol.452
, Issue.7186
, pp. 436-441
-
-
Losonczy, A.1
Makara, J.K.2
Magee, J.C.3
-
83
-
-
37549053317
-
Locally Dynamic Synaptic Learning Rules in Pyramidal Neuron Dendrites
-
18097401 1:CAS:528:DC%2BD2sXhsVGjsL7P
-
CD Harvey K Svoboda 2007 Locally Dynamic Synaptic Learning Rules in Pyramidal Neuron Dendrites Nature 450 7173 1195 1200 18097401 1:CAS:528:DC%2BD2sXhsVGjsL7P
-
(2007)
Nature
, vol.450
, Issue.7173
, pp. 1195-1200
-
-
Harvey, C.D.1
Svoboda, K.2
-
84
-
-
0037174618
-
Alzheimer's disease is a synaptic failure
-
DOI 10.1126/science.1074069
-
DJ Selkoe 2002 Alzheimer's Disease Is a Synaptic Failure Science 298 5594 789 791 12399581 1:CAS:528:DC%2BD38XotFSnur0%3D (Pubitemid 35231524)
-
(2002)
Science
, vol.298
, Issue.5594
, pp. 789-791
-
-
Selkoe, D.J.1
-
85
-
-
23044468691
-
The synaptic Aβ hypothesis of Alzheimer disease
-
DOI 10.1038/nn0805-977
-
RE Tanzi 2005 The Synaptic A[beta] Hypothesis of Alzheimer Disease Nat Neurosci 8 8 977 979 16047022 1:CAS:528:DC%2BD2MXmsFWmtrk%3D (Pubitemid 41061502)
-
(2005)
Nature Neuroscience
, vol.8
, Issue.8
, pp. 977-979
-
-
Tanzi, R.E.1
-
86
-
-
23044445669
-
Regulation of NMDA receptor trafficking by amyloid-β
-
DOI 10.1038/nn1503
-
E Snyder, et al. 2005 Regulation of NMDA Receptor Trafficking by Amyloid-beta Nat Neurosci 8 8 1051 1058 16025111 1:CAS:528:DC%2BD2MXmsFWmtL8%3D (Pubitemid 41061516)
-
(2005)
Nature Neuroscience
, vol.8
, Issue.8
, pp. 1051-1058
-
-
Snyder, E.M.1
Nong, Y.2
Almeida, C.G.3
Paul, S.4
Moran, T.5
Choi, E.Y.6
Nairn, A.C.7
Salter, M.W.8
Lombroso, P.J.9
Gouras, G.K.10
Greengard, P.11
-
87
-
-
78650970378
-
Reversing EphB2 Depletion Rescues Cognitive Functions in Alzheimer Model
-
21113149 1:CAS:528:DC%2BC3cXhsVOrsbzE
-
M Cisse, et al. 2011 Reversing EphB2 Depletion Rescues Cognitive Functions in Alzheimer Model Nature 469 7328 47 52 21113149 1:CAS:528: DC%2BC3cXhsVOrsbzE
-
(2011)
Nature
, vol.469
, Issue.7328
, pp. 47-52
-
-
Cisse, M.1
-
88
-
-
0037127073
-
Modulation of NMDA receptor - Dependent calcium influx and gene expression through EphB receptors
-
DOI 10.1126/science.1065983
-
M Takasu M Dalva R Zigmond M Greenberg 2002 Modulation of NMDA Receptor-dependent Calcium Influx and Gene Expression through EphB Receptors Science 295 5554 491 495 11799243 1:CAS:528:DC%2BD38XnvFWnuw%3D%3D (Pubitemid 34101638)
-
(2002)
Science
, vol.295
, Issue.5554
, pp. 491-495
-
-
Takasu, M.A.1
Dalva, M.B.2
Zigmond, R.E.3
Greenberg, M.E.4
-
89
-
-
33845411954
-
AMPAR Removal Underlies Aβ-Induced Synaptic Depression and Dendritic Spine Loss
-
DOI 10.1016/j.neuron.2006.10.035, PII S0896627306008725
-
H Hsieh, et al. 2006 AMPAR Removal Underlies A[beta]-Induced Synaptic Depression and Dendritic Spine Loss Neuron 52 5 831 843 17145504 1:CAS:528:DC%2BD28XhtlCnsr7M (Pubitemid 44828454)
-
(2006)
Neuron
, vol.52
, Issue.5
, pp. 831-843
-
-
Hsieh, H.1
Boehm, J.2
Sato, C.3
Iwatsubo, T.4
Tomita, T.5
Sisodia, S.6
Malinow, R.7
-
90
-
-
49149124343
-
Amyloid-[beta] Protein Dimers Isolated Directly from Alzheimer's Brains Impair Synaptic Plasticity and Memory
-
18568035 1:CAS:528:DC%2BD1cXptlKltb0%3D
-
GM Shankar, et al. 2008 Amyloid-[beta] Protein Dimers Isolated Directly from Alzheimer's Brains Impair Synaptic Plasticity and Memory Nat Med 14 8 837 842 18568035 1:CAS:528:DC%2BD1cXptlKltb0%3D
-
(2008)
Nat Med
, vol.14
, Issue.8
, pp. 837-842
-
-
Shankar, G.M.1
-
91
-
-
0033609008
-
Plaque-induced neurite abnormalities: Implications for disruption of neural networks in Alzheimer's disease
-
DOI 10.1073/pnas.96.9.5274
-
RB Knowles, et al. 1999 Plaque-Induced Neurite Abnormalities: Implications for Disruption of Neural Networks in Alzheimer's Disease Proc Natl Acad Sci USA 96 9 5274 5279 10220456 1:CAS:528:DyaK1MXjtVKmurg%3D (Pubitemid 29214573)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.9
, pp. 5274-5279
-
-
Knowles, R.B.1
Wyart, C.2
Buldyrev, S.V.3
Cruz, L.4
Urbanc, B.5
Hasselmo, M.E.6
Stanley, H.E.7
Hyman, B.T.8
-
92
-
-
52249115856
-
Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease
-
18802001 1:CAS:528:DC%2BD1cXhtFamtrvJ
-
MA Busche, et al. 2008 Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease Science 321 5896 1686 1689 18802001 1:CAS:528:DC%2BD1cXhtFamtrvJ
-
(2008)
Science
, vol.321
, Issue.5896
, pp. 1686-1689
-
-
Busche, M.A.1
-
93
-
-
0002377794
-
The cellular basis of cortical disconnection in Alzheimer's disease and relating dementing conditions
-
R. Katzman K.L. Bick R.D. Terry (eds). Raven New York
-
Hof PR, Morrison JH (1994) The cellular basis of cortical disconnection in Alzheimer's disease and relating dementing conditions. In: Katzman R, Bick KL, Terry RD (eds) Alzheimer's disease. Raven, New York, pp 197-228
-
(1994)
Alzheimer's Disease
, pp. 197-228
-
-
Hof, P.R.1
Morrison, J.H.2
-
94
-
-
61349096009
-
Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice
-
19251629 1:CAS:528:DC%2BD1MXit1eltbY%3D
-
K Kuchibhotla C Lattarulo B Hyman B Bacskai 2009 Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice Science 323 5918 1211 1215 19251629 1:CAS:528:DC%2BD1MXit1eltbY%3D
-
(2009)
Science
, vol.323
, Issue.5918
, pp. 1211-1215
-
-
Kuchibhotla, K.1
Lattarulo, C.2
Hyman, B.3
Bacskai, B.4
-
95
-
-
47749113650
-
Aβ Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks
-
DOI 10.1016/j.neuron.2008.06.008, PII S0896627308005011
-
K Kuchibhotla, et al. 2008 Abeta Plaques Lead to Aberrant Regulation of Calcium Homeostasis in vivo Resulting in Structural and Functional Disruption of Neuronal Networks Neuron 59 2 214 225 18667150 1:CAS:528:DC%2BD1cXpsFOgtrk%3D (Pubitemid 352033686)
-
(2008)
Neuron
, vol.59
, Issue.2
, pp. 214-225
-
-
Kuchibhotla, K.V.1
Goldman, S.T.2
Lattarulo, C.R.3
Wu, H.-Y.4
Hyman, B.T.5
Bacskai, B.J.6
-
96
-
-
65549153713
-
Expression of Human Amyloid Precursor Protein in Rat Cortical Neurons Inhibits Calcium Oscillations
-
19369541 1:CAS:528:DC%2BD1MXltFShsrs%3D
-
S Santos, et al. 2009 Expression of Human Amyloid Precursor Protein in Rat Cortical Neurons Inhibits Calcium Oscillations J Neurosci 29 15 4708 4718 19369541 1:CAS:528:DC%2BD1MXltFShsrs%3D
-
(2009)
J Neurosci
, vol.29
, Issue.15
, pp. 4708-4718
-
-
Santos, S.1
-
97
-
-
33749081115
-
Neural Synchrony in Brain Disorders: Relevance for Cognitive Dysfunctions and Pathophysiology
-
DOI 10.1016/j.neuron.2006.09.020, PII S0896627306007276
-
PJ Uhlhaas W Singer 2006 Neural Synchrony in Brain Disorders: Relevance for Cognitive Dysfunctions and Pathophysiology Neuron 52 1 155 168 17015233 1:CAS:528:DC%2BD28XhtFentr7K (Pubitemid 44466360)
-
(2006)
Neuron
, vol.52
, Issue.1
, pp. 155-168
-
-
Uhlhaas, P.J.1
Singer, W.2
-
99
-
-
2942616619
-
EEG dynamics in patients with Alzheimer's disease
-
DOI 10.1016/j.clinph.2004.01.001, PII S138824570400015X
-
J Jeong 2004 EEG Dynamics in Patients with Alzheimer's Disease Clin Neurophysiol 115 7 1490 1505 15203050 (Pubitemid 38760295)
-
(2004)
Clinical Neurophysiology
, vol.115
, Issue.7
, pp. 1490-1505
-
-
Jeong, J.1
-
100
-
-
2942614303
-
The Electroencephalogram in Dementia; Some Preliminary Observations and Correlations
-
13330660 1:STN:280:DyaG28%2FotlaltA%3D%3D
-
H Weiner DB Schuster 1956 The Electroencephalogram in Dementia; Some Preliminary Observations and Correlations Electroencephalogr Clin Neurophysiol 8 3 479 488 13330660 1:STN:280:DyaG28%2FotlaltA%3D%3D
-
(1956)
Electroencephalogr Clin Neurophysiol
, vol.8
, Issue.3
, pp. 479-488
-
-
Weiner, H.1
Schuster, D.B.2
-
101
-
-
0034622247
-
Quantitative electroencephalography in mild cognitive impairment: Longitudinal changes and possible prediction of Alzheimer's disease
-
DOI 10.1016/S0197-4580(00)00153-6, PII S0197458000001536
-
V Jelic, et al. 2000 Quantitative Electroencephalography in Mild Cognitive Impairment: Longitudinal Changes and Possible Prediction of Alzheimer's Disease Neurobiol Aging 21 4 533 540 10924766 1:STN:280: DC%2BD3cvit1WntQ%3D%3D (Pubitemid 30621491)
-
(2000)
Neurobiology of Aging
, vol.21
, Issue.4
, pp. 533-540
-
-
Jelic, V.1
Johansson, S.-E.2
Almkvist, O.3
Shigeta, M.4
Julin, P.5
Nordberg, A.6
Winblad, B.7
Wahlund, L.-O.8
-
102
-
-
77954132249
-
Amyloid-[beta]-induced Neuronal Dysfunction in Alzheimer's Disease: From Synapses Toward Neural Networks
-
20581818 1:CAS:528:DC%2BC3cXnvFSgtr0%3D
-
JJ Palop L Mucke 2010 Amyloid-[beta]-induced Neuronal Dysfunction in Alzheimer's Disease: From Synapses Toward Neural Networks Nat Neurosci 13 7 812 818 20581818 1:CAS:528:DC%2BC3cXnvFSgtr0%3D
-
(2010)
Nat Neurosci
, vol.13
, Issue.7
, pp. 812-818
-
-
Palop, J.J.1
Mucke, L.2
-
103
-
-
0028217198
-
Quantitative EEG analysis in early onset Alzheimer's disease: Correlations with severity, clinical characteristics, visual EEG and CCT
-
DOI 10.1016/0013-4694(94)90144-9
-
U Schreiter-Gasser T Gasser P Ziegler 1994 Quantitative EEG Analysis in Early Onset Alzheimer's Disease: Correlations with Severity, Clinical Characteristics, Visual EEG and CCT Electroencephalogr Clin Neurophysiol 90 4 267 272 7512907 1:STN:280:DyaK2c3hsFGhuw%3D%3D (Pubitemid 24118519)
-
(1994)
Electroencephalography and Clinical Neurophysiology
, vol.90
, Issue.4
, pp. 267-272
-
-
Schreiter-Gasser, U.1
Gasser, T.2
Ziegler, P.3
-
104
-
-
3543002838
-
Quantitative spectral electroencephalography in predicting survival in patients with early Alzheimer disease
-
DOI 10.1001/archneur.55.8.1105
-
JJ Claus, et al. 1998 Quantitative Spectral Electroencephalography in Predicting Survival in Patients with Early Alzheimer Disease Arch Neurol 55 8 1105 1111 9708961 1:STN:280:DyaK1cznt1KqsA%3D%3D (Pubitemid 28367236)
-
(1998)
Archives of Neurology
, vol.55
, Issue.8
, pp. 1105-1111
-
-
Claus, J.J.1
Ongerboer De Visser, B.W.2
Walstra, G.J.M.3
Hijdra, A.4
Verbeeten Jr., B.5
Van Gool, W.A.6
-
105
-
-
0020445685
-
Temporal relationship between sniffing and the limbic theta rhythm during odor discrimination reversal learning
-
7143047 1:STN:280:DyaL3s%2FlvVyktg%3D%3D
-
F Macrides HB Eichenbaum WB Forbes 1982 Temporal relationship between sniffing and the limbic theta rhythm during odor discrimination reversal learning J Neurosci 2 1705 1711 7143047 1:STN:280:DyaL3s%2FlvVyktg%3D%3D
-
(1982)
J Neurosci
, vol.2
, pp. 1705-1711
-
-
MacRides, F.1
Eichenbaum, H.B.2
Forbes, W.B.3
-
107
-
-
77955860261
-
Decreased Rhythmic GABAergic Septal Activity and Memory-associated Theta Oscillations after Hippocampal Amyloid-beta Pathology in the Rat
-
20720106 1:CAS:528:DC%2BC3cXhtFWms7zN
-
V Villette, et al. 2010 Decreased Rhythmic GABAergic Septal Activity and Memory-associated Theta Oscillations after Hippocampal Amyloid-beta Pathology in the Rat J Neurosci 30 33 10991 11003 20720106 1:CAS:528:DC%2BC3cXhtFWms7zN
-
(2010)
J Neurosci
, vol.30
, Issue.33
, pp. 10991-11003
-
-
Villette, V.1
-
108
-
-
33745258377
-
Incidence and predictors of seizures in patients with Alzheimer's disease
-
DOI 10.1111/j.1528-1167.2006.00554.x
-
J Amatniek, et al. 2006 Incidence and Predictors of Seizures in Patients with Alzheimer's Disease Epilepsia 47 5 867 872 16686651 (Pubitemid 44030181)
-
(2006)
Epilepsia
, vol.47
, Issue.5
, pp. 867-872
-
-
Amatniek, J.C.1
Hauser, W.A.2
DelCastillo-Castaneda, C.3
Jacobs, D.M.4
Marder, K.5
Bell, K.6
Albert, M.7
Brandt, J.8
Stern, Y.9
-
109
-
-
63849180498
-
Amyloid Beta-induced Neuronal Hyperexcitability Triggers Progressive Epilepsy
-
19295151 1:CAS:528:DC%2BD1MXjs1Wmur8%3D
-
R Minkeviciene, et al. 2009 Amyloid Beta-induced Neuronal Hyperexcitability Triggers Progressive Epilepsy J Neurosci 29 11 3453 3462 19295151 1:CAS:528:DC%2BD1MXjs1Wmur8%3D
-
(2009)
J Neurosci
, vol.29
, Issue.11
, pp. 3453-3462
-
-
Minkeviciene, R.1
-
110
-
-
34548264782
-
Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease
-
DOI 10.1016/j.neuron.2007.07.025, PII S0896627307005703
-
J Palop, et al. 2007 Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease Neuron 55 5 697 711 17785178 1:CAS:528:DC%2BD2sXhtV2qtrfO (Pubitemid 47321079)
-
(2007)
Neuron
, vol.55
, Issue.5
, pp. 697-711
-
-
Palop, J.J.1
Chin, J.2
Roberson, E.D.3
Wang, J.4
Thwin, M.T.5
Bien-Ly, N.6
Yoo, J.7
Ho, K.O.8
Yu, G.-Q.9
Kreitzer, A.10
Finkbeiner, S.11
Noebels, J.L.12
Mucke, L.13
-
111
-
-
11144294808
-
Neurobehavioral characterization of APP23 transgenic mice with the SHIRPA primary screen
-
DOI 10.1016/j.bbr.2004.06.020, PII S0166432804002463
-
R Lalonde M Dumont M Staufenbiel C Strazielle 2005 Neurobehavioral Characterization of APP23 Transgenic Mice with the SHIRPA Primary Screen Behav Brain Res 157 1 91 98 15617775 1:CAS:528:DC%2BD2cXhtFGhsbjM (Pubitemid 40029703)
-
(2005)
Behavioural Brain Research
, vol.157
, Issue.1
, pp. 91-98
-
-
Lalonde, R.1
Dumont, M.2
Staufenbiel, M.3
Strazielle, C.4
-
112
-
-
0015145985
-
The Hippocampus as a Spatial Map. Preliminary Evidence from Unit Activity in the Freely-moving Rat
-
5124915
-
J O'Keefe J Dostrovsky 1971 The Hippocampus as a Spatial Map. Preliminary Evidence from Unit Activity in the Freely-moving Rat Brain Res 34 1 171 175 5124915
-
(1971)
Brain Res
, vol.34
, Issue.1
, pp. 171-175
-
-
O'Keefe, J.1
Dostrovsky, J.2
-
114
-
-
58149385218
-
Picomolar Amyloid-{beta} Positively Modulates Synaptic Plasticity and Memory in Hippocampus
-
19118188 1:CAS:528:DC%2BD1MXnsF2msw%3D%3D
-
D Puzzo, et al. 2008 Picomolar Amyloid-{beta} Positively Modulates Synaptic Plasticity and Memory in Hippocampus J Neurosci 28 53 14537 14545 19118188 1:CAS:528:DC%2BD1MXnsF2msw%3D%3D
-
(2008)
J Neurosci
, vol.28
, Issue.53
, pp. 14537-14545
-
-
Puzzo, D.1
-
115
-
-
77955322042
-
Dendritic Function of Tau Mediates Amyloid-beta Toxicity in Alzheimer's Disease Mouse Models
-
20655099 1:CAS:528:DC%2BC3cXpvFKrtr4%3D
-
L Ittner, et al. 2010 Dendritic Function of Tau Mediates Amyloid-beta Toxicity in Alzheimer's Disease Mouse Models Cell 142 3 387 397 20655099 1:CAS:528:DC%2BC3cXpvFKrtr4%3D
-
(2010)
Cell
, vol.142
, Issue.3
, pp. 387-397
-
-
Ittner, L.1
-
116
-
-
2442711560
-
Fyn kinase modulates synaptotoxicity, but not aberrant sprouting, in human amyloid precursor protein transgenic mice
-
DOI 10.1523/JNEUROSCI.0277-04.2004
-
J Chin, et al. 2004 Fyn Kinase Modulates Synaptotoxicity, But Not Aberrant Sprouting, in Human Amyloid Precursor Protein Transgenic Mice J Neurosci 24 19 4692 4697 15140940 1:CAS:528:DC%2BD2cXksFCqu74%3D (Pubitemid 38656624)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.19
, pp. 4692-4697
-
-
Chin, J.1
Palop, J.J.2
Yu, G.-Q.3
Kojima, N.4
Masliah, E.5
Mucke, L.6
-
117
-
-
17944382037
-
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
-
DOI 10.1126/science.1058189
-
J Lewis 2001 Enhanced Neurofibrillary Degeneration in Transgenic Mice Expressing Mutant Tau and APP Science 293 1487 1491 11520987 1:CAS:528:DC%2BD3MXmsVeru7Y%3D (Pubitemid 32801551)
-
(2001)
Science
, vol.293
, Issue.5534
, pp. 1487-1491
-
-
Lewis, J.1
Dickson, D.W.2
Lin, W.-L.3
Chisholm, L.4
Corral, A.5
Jones, G.6
Yen, S.-H.7
Sahara, N.8
Skipper, L.9
Yager, D.10
Eckman, C.11
Hardy, J.12
Hutton, M.13
McGowan, E.14
-
118
-
-
0034992339
-
Tau and transgenic animal models
-
DOI 10.1016/S0165-0173(01)00055-8, PII S0165017301000558
-
J Gotz 2001 Tau and Transgenic Animal Models Brain Res Rev 35 3 266 286 11423157 1:CAS:528:DC%2BD3MXksVGmu7o%3D (Pubitemid 32566200)
-
(2001)
Brain Research Reviews
, vol.35
, Issue.3
, pp. 266-286
-
-
Gotz, J.1
-
119
-
-
67949086707
-
Presenilins are Essential for Regulating Neurotransmitter Release
-
19641596 1:CAS:528:DC%2BD1MXpt1Wgsr4%3D
-
C Zhang, et al. 2009 Presenilins are Essential for Regulating Neurotransmitter Release Nature 460 7255 632 636 19641596 1:CAS:528: DC%2BD1MXpt1Wgsr4%3D
-
(2009)
Nature
, vol.460
, Issue.7255
, pp. 632-636
-
-
Zhang, C.1
-
120
-
-
78149259168
-
Inactivation of Presenilins Causes Pre-synaptic Impairment Prior to Post-synaptic Dysfunction
-
20854432 1:CAS:528:DC%2BC3cXhsFWhsr7K
-
D Zhang, et al. 2010 Inactivation of Presenilins Causes Pre-synaptic Impairment Prior to Post-synaptic Dysfunction J Neurochem 115 5 1215 1221 20854432 1:CAS:528:DC%2BC3cXhsFWhsr7K
-
(2010)
J Neurochem
, vol.115
, Issue.5
, pp. 1215-1221
-
-
Zhang, D.1
-
121
-
-
11344290171
-
NMDA receptor-dependent activation of the small GTPase Rab5 drives the removal of synaptic AMPA receptors during hippocampal LTD
-
DOI 10.1016/j.neuron.2004.12.023, PII S0896627304008359
-
T Brown I Tran D Backos J Esteban 2005 NMDA Receptor-dependent Activation of the Small GTPase Rab5 Drives the Removal of Synaptic AMPA Receptors during Hippocampal LTD Neuron 45 1 81 94 15629704 1:CAS:528:DC%2BD2MXmtl2ktA%3D%3D (Pubitemid 40075351)
-
(2005)
Neuron
, vol.45
, Issue.1
, pp. 81-94
-
-
Brown, T.C.1
Tran, I.C.2
Backos, D.S.3
Esteban, J.A.4
-
122
-
-
34447123766
-
Rab5 mediates an amyloid precursor protein signaling pathway that leads to apoptosis
-
DOI 10.1523/JNEUROSCI.4599-06.2007
-
D Laifenfeld, et al. 2007 Rab5 Mediates an Amyloid Precursor Protein Signaling Pathway That Leads to Apoptosis J Neurosci 27 27 7141 7153 17611268 1:CAS:528:DC%2BD2sXot1egt7o%3D (Pubitemid 47037567)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.27
, pp. 7141-7153
-
-
Laifenfeld, D.1
Patzek, L.J.2
McPhie, D.L.3
Chen, Y.4
Levites, Y.5
Cataldo, A.M.6
Neve, R.L.7
-
123
-
-
36549068174
-
Disruption of Large-Scale Brain Systems in Advanced Aging
-
DOI 10.1016/j.neuron.2007.10.038, PII S0896627307008641
-
JR Andrews-Hanna, et al. 2007 Disruption of Large-Scale Brain Systems in Advanced Aging Neuron 56 5 924 935 18054866 1:CAS:528:DC%2BD2sXhsVOrsLfP (Pubitemid 350181355)
-
(2007)
Neuron
, vol.56
, Issue.5
, pp. 924-935
-
-
Andrews-Hanna, J.R.1
Snyder, A.Z.2
Vincent, J.L.3
Lustig, C.4
Head, D.5
Raichle, MarcusE.6
Buckner, R.L.7
-
125
-
-
77951819352
-
Blood-Borne Amyloid-{beta} Dimer Correlates with Clinical Markers of Alzheimer's Disease
-
20445057 1:CAS:528:DC%2BC3cXovVWmsbo%3D
-
VL Villemagne, et al. 2010 Blood-Borne Amyloid-{beta} Dimer Correlates with Clinical Markers of Alzheimer's Disease J Neurosci 30 18 6315 6322 20445057 1:CAS:528:DC%2BC3cXovVWmsbo%3D
-
(2010)
J Neurosci
, vol.30
, Issue.18
, pp. 6315-6322
-
-
Villemagne, V.L.1
-
126
-
-
67649531853
-
Biomarkers of Alzheimer's Disease
-
19010417 1:CAS:528:DC%2BD1MXotFCgtro%3D
-
R Craig-Schapiro AM Fagan DM Holtzman 2009 Biomarkers of Alzheimer's Disease Neurobiol Dis 35 2 128 140 19010417 1:CAS:528:DC%2BD1MXotFCgtro%3D
-
(2009)
Neurobiol Dis
, vol.35
, Issue.2
, pp. 128-140
-
-
Craig-Schapiro, R.1
Fagan, A.M.2
Holtzman, D.M.3
-
127
-
-
0034988318
-
Correlation between cognitive deficits and Aβ deposits in transgenic APP+PS1 mice
-
DOI 10.1016/S0197-4580(00)00249-9, PII S0197458000002499
-
MN Gordon, et al. 2001 Correlation Between Cognitive Deficits and A[beta] Deposits in Transgenic APP∈+∈PS1 Mice Neurobiol Aging 22 3 377 385 11378242 1:CAS:528:DC%2BD3MXjvFSjs70%3D (Pubitemid 32510908)
-
(2001)
Neurobiology of Aging
, vol.22
, Issue.3
, pp. 377-385
-
-
Gordon, M.N.1
King, D.L.2
Diamond, D.M.3
Jantzen, P.T.4
Boyett, K.V.5
Hope, C.E.6
Hatcher, J.M.7
DiCarlo, G.8
Gottschall, W.P.E.9
Morgan, D.10
Arendash, G.W.11
-
128
-
-
79958280319
-
Novel age-dependent learning deficits in a mouse model of Alzheimer's disease: Implications for translational research
-
in press
-
Montgomery KS et al. (2009) Novel age-dependent learning deficits in a mouse model of Alzheimer's disease: Implications for translational research. Neurobiol Aging, in press
-
Neurobiol Aging
, pp. 2009
-
-
Montgomery, K.S.1
-
129
-
-
74949090244
-
Olfactory Dysfunction Correlates with β-Amyloid Plaque Burden in an Alzheimer's Disease Mouse Model
-
20071513 1:CAS:528:DC%2BC3cXhtFahtrg%3D
-
DW Wesson E Levy RA Nixon DW Wilson 2010 Olfactory Dysfunction Correlates with β-Amyloid Plaque Burden in an Alzheimer's Disease Mouse Model J Neurosci 30 2 505 514 20071513 1:CAS:528:DC%2BC3cXhtFahtrg%3D
-
(2010)
J Neurosci
, vol.30
, Issue.2
, pp. 505-514
-
-
Wesson, D.W.1
Levy, E.2
Nixon, R.A.3
Wilson, D.W.4
-
130
-
-
0029742199
-
Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice
-
DOI 10.1126/science.274.5284.99
-
K Hsiao, et al. 1996 Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice Science 274 5284 99 102 8810256 1:CAS:528:DyaK28XmtVyns7c%3D (Pubitemid 26332733)
-
(1996)
Science
, vol.274
, Issue.5284
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
131
-
-
0036489445
-
The relationship between Aβ and memory in the Tg2576 mouse model of Alzheimer's disease
-
MA Westerman, et al. 2002 The Relationship Between Abeta and Memory in the Tg2576 Mouse Model of Alzheimer's Disease J Neurosci 22 5 1858 1867 11880515 1:CAS:528:DC%2BD38XhvValu78%3D (Pubitemid 35386304)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.5
, pp. 1858-1867
-
-
Westerman, M.A.1
Cooper-Blacketer, D.2
Mariash, A.3
Kotilinek, L.4
Kawarabayashi, T.5
Younkin, L.H.6
Carlson, G.A.7
Younkin, S.G.8
Ashe, K.H.9
-
132
-
-
0028985574
-
Alzheimer-type Neuropathology in Transgenic Mice Overexpressing V717F [beta]-amyloid Precursor Protein
-
7845465 1:CAS:528:DyaK2MXjs1Wns7w%3D
-
D Games, et al. 1995 Alzheimer-type Neuropathology in Transgenic Mice Overexpressing V717F [beta]-amyloid Precursor Protein Nature 373 6514 523 527 7845465 1:CAS:528:DyaK2MXjs1Wns7w%3D
-
(1995)
Nature
, vol.373
, Issue.6514
, pp. 523-527
-
-
Games, D.1
-
133
-
-
0034700480
-
A learning deficit related to age and β-amyloid plaques in a mouse model of alzheimer's disease
-
DOI 10.1038/35050103
-
G Chen, et al. 2000 A Learning Deficit Related to Age and Beta-amyloid Plaques in a Mouse Model of Alzheimer's Disease Nature 408 6815 975 979 11140684 1:CAS:528:DC%2BD3MXhslWjsQ%3D%3D (Pubitemid 32101643)
-
(2000)
Nature
, vol.408
, Issue.6815
, pp. 975-979
-
-
Chen, G.1
Chen, K.S.2
Knox, J.3
Inglis, J.4
Bernard, A.5
Martin, S.J.6
Justice, A.7
McConlogue, L.8
Games, D.9
Freedman, S.B.10
Morris, R.G.M.11
-
134
-
-
77955290621
-
Days to Criterion as an Indicator of Toxicity Associated with Human Alzheimer Amyloid-beta Oligomers
-
20641005 1:CAS:528:DC%2BC3cXhtFWgsLvP
-
S Gandy, et al. 2010 Days to Criterion as an Indicator of Toxicity Associated with Human Alzheimer Amyloid-beta Oligomers Ann Neurol 68 2 220 230 20641005 1:CAS:528:DC%2BC3cXhtFWgsLvP
-
(2010)
Ann Neurol
, vol.68
, Issue.2
, pp. 220-230
-
-
Gandy, S.1
-
135
-
-
34547400006
-
Aging, Alzheimer's disease, and hearing impairment: Highlighting relevant issues and calling for additional research
-
DOI 10.1044/1059-0889(2007/001)
-
AT Cacace 2007 Aging, Alzheimer's Disease, and Hearing Impairment: Highlighting Relevant Issues and Calling for Additional Research Am J Audiol 16 1 2 3 17562751 (Pubitemid 351250992)
-
(2007)
American Journal of Audiology
, vol.16
, Issue.1
, pp. 2-3
-
-
Cacace, A.T.1
-
136
-
-
0026387819
-
Visual Function in Alzheimer's Disease and Normal Aging
-
1776752 1:STN:280:DyaK387jtl2jtg%3D%3D
-
A Cronin-Golomb J Rizzo S Corkin J Growdon 1991 Visual Function in Alzheimer's Disease and Normal Aging Ann NY Acad Sci 640 28 35 1776752 1:STN:280:DyaK387jtl2jtg%3D%3D
-
(1991)
Ann NY Acad Sci
, vol.640
, pp. 28-35
-
-
Cronin-Golomb, A.1
Rizzo, J.2
Corkin, S.3
Growdon, J.4
-
137
-
-
0033040685
-
Loss of olfactory function in dementing disease
-
DOI 10.1016/S0031-9384(98)00262-5, PII S0031938498002625
-
C Murphy 1999 Loss of Olfactory Function in Dementing Disease Physiol Behav 66 2 177 182 10336141 1:CAS:528:DyaK1MXjtFGmtrs%3D (Pubitemid 29206506)
-
(1999)
Physiology and Behavior
, vol.66
, Issue.2
, pp. 177-182
-
-
Murphy, C.1
-
138
-
-
0031886320
-
Olfaction in neurodegenerative disease: A meta-analysis of olfactory functioning in Ahlzheimer's and Parkinson's diseases
-
DOI 10.1001/archneur.55.1.84
-
RI Mesholam PJ Moberg RN Mahr RL Doty 1998 Olfaction in Neurodegenerative Disease: A Meta-analysis of Olfactory Functioning in Alzheimer's and Parkinson's Diseases Arch Neurol 55 1 84 90 9443714 1:STN:280: DyaK1c7gtl2msw%3D%3D (Pubitemid 28139109)
-
(1998)
Archives of Neurology
, vol.55
, Issue.1
, pp. 84-90
-
-
Mesholam, R.I.1
Moberg, P.J.2
Mahr, R.N.3
Doty, R.L.4
-
139
-
-
1842505579
-
Olfactory dysfunction occurs in transgenic mice overexpressing human τ protein
-
DOI 10.1016/j.brainres.2004.01.047, PII S000689930400160X
-
JB Macknin M Higuchi VMY Lee JQ Trojanowski RL Doty 2004 Olfactory Dysfunction Occurs in Transgenic Mice Overexpressing Human [tau] Protein Brain Res 1000 1-2 174 178 15053964 1:CAS:528:DC%2BD2cXisF2htbY%3D (Pubitemid 38446501)
-
(2004)
Brain Research
, vol.1000
, Issue.1-2
, pp. 174-178
-
-
Macknin, J.B.1
Higuchi, M.2
Lee, V.M.-Y.3
Trojanowski, J.Q.4
Doty, R.L.5
-
140
-
-
57749114849
-
Early Locus Coeruleus Degeneration and Olfactory Dysfunctions in Tg2576 Mice
-
17618708
-
D Guérin J Sacquet N Mandairon F Jourdan A Didier 2009 Early Locus Coeruleus Degeneration and Olfactory Dysfunctions in Tg2576 Mice Neurobiol Aging 30 2 272 283 17618708
-
(2009)
Neurobiol Aging
, vol.30
, Issue.2
, pp. 272-283
-
-
Guérin, D.1
Sacquet, J.2
Mandairon, N.3
Jourdan, F.4
Didier, A.5
-
141
-
-
78650716872
-
Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits
-
21186265
-
DS Yang, et al. 2011 Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits Brain 134 1 258 277 21186265
-
(2011)
Brain
, vol.134
, Issue.1
, pp. 258-277
-
-
Yang, D.S.1
-
142
-
-
60349125886
-
Reassessing the Amyloid Cascade Hypothesis of Alzheimer's Disease
-
19124085 1:CAS:528:DC%2BD1MXit1Krsb0%3D
-
S Pimplikar 2009 Reassessing the Amyloid Cascade Hypothesis of Alzheimer's Disease Int J Biochem Cell Biol 41 6 1261 1268 19124085 1:CAS:528:DC%2BD1MXit1Krsb0%3D
-
(2009)
Int J Biochem Cell Biol
, vol.41
, Issue.6
, pp. 1261-1268
-
-
Pimplikar, S.1
-
143
-
-
84987472540
-
Differences in Olfactory Test Performance between Normal Aged, Alzheimer and vascular type dementia individuals
-
L Knupfer R Spiegel 1986 Differences in Olfactory Test Performance Between Normal Aged, Alzheimer and vascular type dementia individuals Int J Geriatr Psychiatry 1 1 3 14
-
(1986)
Int J Geriatr Psychiatry
, vol.1
, Issue.1
, pp. 3-14
-
-
Knupfer, L.1
Spiegel, R.2
-
144
-
-
0021708157
-
Smell identification ability: Changes with age
-
RL Doty P Shaman SL Applebaum R Giberson L Sikorski L Rosenberg 1984 Smell Identification Ability: Changes with Age Science 226 1441 1443 6505700 1:STN:280:DyaL2M%2FmsFOqtQ%3D%3D (Pubitemid 15161278)
-
(1984)
Science
, vol.226
, Issue.4681
, pp. 1441-1443
-
-
Doty, R.L.1
Shaman, P.2
Applebaum, S.L.3
-
145
-
-
0033389723
-
Very early decline in recognition memory for odors in Alzheimer's disease
-
C Murphy S Nordin S Jinich 1999 Very early decline in recognition memory for odors in Alzheimer's disease Aging Neuropsychol Cogn 6 229 240 (Pubitemid 30108398)
-
(1999)
Aging, Neuropsychology, and Cognition
, vol.6
, Issue.3
, pp. 229-240
-
-
Murphy, C.1
Nordin, S.2
Jinich, S.3
-
146
-
-
77951833484
-
Should Olfactory Dysfunction be used as a Biomarker of Alzheimer's Disease?
-
20420483
-
DW Wesson DA Wilson RA Nixon 2010 Should Olfactory Dysfunction be used as a Biomarker of Alzheimer's Disease? Expert Rev Neurother 10 5 633 635 20420483
-
(2010)
Expert Rev Neurother
, vol.10
, Issue.5
, pp. 633-635
-
-
Wesson, D.W.1
Wilson, D.A.2
Nixon, R.A.3
-
147
-
-
77951893095
-
Beneficial Effect of Human Anti-amyloid-{beta} Active Immunization on Neurite Morphology and Tau Pathology
-
20360050
-
A Serrano-Pozo, et al. 2010 Beneficial Effect of Human Anti-amyloid-{beta} Active Immunization on Neurite Morphology and Tau Pathology Brain 133 5 1312 1327 20360050
-
(2010)
Brain
, vol.133
, Issue.5
, pp. 1312-1327
-
-
Serrano-Pozo, A.1
-
148
-
-
63149148789
-
Intracerebroventricular Amyloid-B Antibodies Reduce Cerebral Amyloid Angiopathy and Associated Micro-hemorrhages in Aged Tg2576 Mice
-
19246392 1:CAS:528:DC%2BD1MXjslGltLw%3D
-
DR Thakker, et al. 2009 Intracerebroventricular Amyloid-B Antibodies Reduce Cerebral Amyloid Angiopathy and Associated Micro-hemorrhages in Aged Tg2576 Mice Proc Natl Acad Sci 106 11 4501 4506 19246392 1:CAS:528: DC%2BD1MXjslGltLw%3D
-
(2009)
Proc Natl Acad Sci
, vol.106
, Issue.11
, pp. 4501-4506
-
-
Thakker, D.R.1
-
149
-
-
0034700471
-
Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
-
DOI 10.1038/35050110
-
C Janus, et al. 2000 A[beta] Peptide Immunization Reduces Behavioural Impairment and Plaques in a Model of Alzheimer's Disease Nature 408 6815 979 982 11140685 1:CAS:528:DC%2BD3MXhslWitg%3D%3D (Pubitemid 32101644)
-
(2000)
Nature
, vol.408
, Issue.6815
, pp. 979-982
-
-
Janus, C.1
Pearson, J.2
McLaurin, J.3
Mathews, P.M.4
Jiang, Y.5
Schmidt, S.D.6
Chishti, M.A.7
Horne, P.8
Heslin, D.9
French, J.10
Mount, H.T.J.11
Nixon, R.A.12
Mercken, M.13
Bergeron, C.14
Fraser, P.E.15
St George-Hyslop, P.16
Westaway, D.17
-
150
-
-
0036240395
-
Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model
-
DOI 10.1038/nn842
-
J-C Dodart, et al. 2002 Immunization Reverses Memory Deficits without Reducing Brain A[beta] Burden in Alzheimer's Disease Model Nat Neurosci 5 5 452 457 11941374 1:CAS:528:DC%2BD38XjtFykurY%3D (Pubitemid 34454251)
-
(2002)
Nature Neuroscience
, vol.5
, Issue.5
, pp. 452-457
-
-
Dodart, J.-C.1
Bales, K.R.2
Gannon, K.S.3
Greene, S.J.4
DeMattos, R.B.5
Mathis, C.6
DeLong, C.A.7
Wu, S.8
Wu, X.9
Holtzman, D.M.10
Paul, S.M.11
-
151
-
-
0033536163
-
Immunization with amyloid-β attenuates Alzheimer disease-like pathology in the PDAPP mouse
-
DOI 10.1038/22124
-
D Schenk, et al. 1999 Immunization with amyloid-[beta] attenuates Alzheimer-disease-like pathology in the PDAPP mouse Nature 400 6740 173 177 10408445 1:CAS:528:DyaK1MXks1Khsbc%3D (Pubitemid 29327547)
-
(1999)
Nature
, vol.400
, Issue.6740
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guldo, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
152
-
-
44649197748
-
ApoE Promotes the Proteolytic Degradation of Aβ
-
DOI 10.1016/j.neuron.2008.04.010, PII S0896627308003280
-
Q Jiang, et al. 2008 ApoE Promotes the Proteolytic Degradation of A[beta] Neuron 58 5 681 693 18549781 1:CAS:528:DC%2BD1cXnvVSqsbY%3D (Pubitemid 351778466)
-
(2008)
Neuron
, vol.58
, Issue.5
, pp. 681-693
-
-
Jiang, Q.1
Lee, C.Y.D.2
Mandrekar, S.3
Wilkinson, B.4
Cramer, P.5
Zelcer, N.6
Mann, K.7
Lamb, B.8
Willson, T.M.9
Collins, J.L.10
Richardson, J.C.11
Smith, J.D.12
Comery, T.A.13
Riddell, D.14
Holtzman, D.M.15
Tontonoz, P.16
Landreth, G.E.17
-
153
-
-
34547531201
-
Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors
-
DOI 10.1073/pnas.0701096104
-
N Zelcer, et al. 2007 Attenuation of Neuroinflammation and Alzheimer's Disease Pathology by Liver x Receptors Proc Natl Acad Sci 104 25 10601 10606 17563384 1:CAS:528:DC%2BD2sXnt1Oisrs%3D (Pubitemid 47185711)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.25
, pp. 10601-10606
-
-
Zelcer, N.1
Khanlou, N.2
Clare, R.3
Jiang, Q.4
Reed-Geaghan, E.G.5
Landreth, G.E.6
Vinters, H.V.7
Tontonoz, P.8
-
154
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
-
DOI 10.1038/nm0198-097
-
L Holcomb, et al. 1998 Accelerated Alzheimer-type Phenotype in Transgenic Mice Carrying Both Mutant Amyloid Precursor Protein and Presenilin 1 Transgenes Nat Med 4 1 97 100 9427614 1:CAS:528:DyaK1cXjt1OhsA%3D%3D (Pubitemid 28133087)
-
(1998)
Nature Medicine
, vol.4
, Issue.1
, pp. 97-100
-
-
Holcomb, L.1
Gordon, M.N.2
Mcgowan, E.3
Yu, X.4
Benkovic, S.5
Jantzen, P.6
Wright, K.7
Saad, I.8
Mueller, R.9
Morgan, D.10
Sanders, S.11
Zehr, C.12
O'Campo, K.13
Hardy, J.14
Prada, C.-M.15
Eckman, C.16
Younkin, S.17
Hsiao, K.18
Duff, K.19
-
155
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
DOI 10.1016/S0896-6273(00)80974-5
-
DR Borchelt, et al. 1997 Accelerated Amyloid Deposition in the Brains of Transgenic Mice Coexpressing Mutant Presenilin 1 and Amyloid Precursor Proteins
-
(1997)
Neuron
, vol.19
, Issue.4
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
Lee, M.K.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Price, D.L.8
Sisodia, S.S.9
-
156
-
-
36549043900
-
Cystatin C inhibits amyloid-β deposition in Alzheimer's disease mouse models
-
DOI 10.1038/ng.2007.29, PII NG200729
-
W Mi, et al. 2007 Cystatin C Inhibits Amyloid-[beta] Deposition in Alzheimer's Disease Mouse Models Nat Genet 39 12 1440 1442 18026100 1:CAS:528:DC%2BD2sXhtlKmtL3I (Pubitemid 350191347)
-
(2007)
Nature Genetics
, vol.39
, Issue.12
, pp. 1440-1442
-
-
Mi, W.1
Pawlik, M.2
Sastre, M.3
Jung, S.S.4
Radvinsky, D.S.5
Klein, A.M.6
Sommer, J.7
Schmidt, S.D.8
Nixon, R.A.9
Mathews, P.M.10
Levy, E.11
-
157
-
-
36549085086
-
Cystatin C Modulates Cerebral [beta]-amyloidosis
-
18026102 1:CAS:528:DC%2BD2sXhtlKmtLrN
-
SA Kaeser, et al. 2007 Cystatin C Modulates Cerebral [beta]-amyloidosis Nat Genet 39 12 1437 1439 18026102 1:CAS:528:DC%2BD2sXhtlKmtLrN
-
(2007)
Nat Genet
, vol.39
, Issue.12
, pp. 1437-1439
-
-
Kaeser, S.A.1
-
158
-
-
77955400675
-
Amyloid beta Precursor Protein Regulates Male Sexual Behavior
-
20668181 1:CAS:528:DC%2BC3cXhtVahsr7M
-
JH Park PJ Bonthius H-W Tsai S Bekiranov EF Rissman 2010 Amyloid beta Precursor Protein Regulates Male Sexual Behavior J Neurosci 30 30 9967 9972 20668181 1:CAS:528:DC%2BC3cXhtVahsr7M
-
(2010)
J Neurosci
, vol.30
, Issue.30
, pp. 9967-9972
-
-
Park, J.H.1
Bonthius, P.J.2
Tsai, H.-W.3
Bekiranov, S.4
Rissman, E.F.5
-
159
-
-
78149412424
-
Age and gene overexpression interact to abolish nesting behavior in Tg2576 amyloid precursor protein (APP) mice
-
20804789 1:CAS:528:DC%2BC3cXhtlykurrL
-
DW Wesson DA Wilson 2011 Age and gene overexpression interact to abolish nesting behavior in Tg2576 amyloid precursor protein (APP) mice Behav Brain Res 216 1 408 413 20804789 1:CAS:528:DC%2BC3cXhtlykurrL
-
(2011)
Behav Brain Res
, vol.216
, Issue.1
, pp. 408-413
-
-
Wesson, D.W.1
Wilson, D.A.2
-
160
-
-
40849136379
-
Age-dependent and -independent Behavioral Deficits in Tg2576 Mice
-
18261809 1:CAS:528:DC%2BD1cXjtleisbo%3D
-
R Deacon, et al. 2008 Age-dependent and -independent Behavioral Deficits in Tg2576 Mice Behav Brain Res 189 1 126 138 18261809 1:CAS:528: DC%2BD1cXjtleisbo%3D
-
(2008)
Behav Brain Res
, vol.189
, Issue.1
, pp. 126-138
-
-
Deacon, R.1
-
161
-
-
63449094785
-
Amyloid Beta Mediates Memory Formation
-
19318468 1:CAS:528:DC%2BC3MXisl2itLw%3D
-
A Garcia-Osta CM Alberini 2009 Amyloid Beta Mediates Memory Formation Learn Mem 16 4 267 272 19318468 1:CAS:528:DC%2BC3MXisl2itLw%3D
-
(2009)
Learn Mem
, vol.16
, Issue.4
, pp. 267-272
-
-
Garcia-Osta, A.1
Alberini, C.M.2
-
162
-
-
0036138044
-
Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau
-
K Tanemura, et al. 2002 Neurodegeneration with Tau Accumulation in a Transgenic Mouse Expressing V337M Human Tau J Neurosci 22 1 133 141 11756496 1:CAS:528:DC%2BD38XislWlug%3D%3D (Pubitemid 34033491)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.1
, pp. 133-141
-
-
Tanemura, K.1
Murayama, M.2
Akagi, T.3
Hashikawa, T.4
Tominaga, T.5
Ichikawa, M.6
Yamaguchi, H.7
Takashima, A.8
-
163
-
-
33745449875
-
An inhibitor of tau hyperphosphorylation prevents severe motor impairments in tau transgenic mice
-
DOI 10.1073/pnas.0602913103
-
S Le Corre, et al. 2006 An inhibitor of Tau Hyperphosphorylation Prevents Severe Motor Impairments in Tau Transgenic Mice Proc Natl Acad Sci USA 103 25 9673 9678 16769887 (Pubitemid 43955883)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.25
, pp. 9673-9678
-
-
Le Corre, S.1
Klafki, H.W.2
Plesnila, N.3
Hubinger, G.4
Obermeier, A.5
Sahagun, H.6
Monse, B.7
Seneci, P.8
Lewis, J.9
Eriksen, J.10
Zehr, C.11
Yue, M.12
McGowan, E.13
Dickson, D.W.14
Hutton, M.15
Roder, H.M.16
-
164
-
-
77951927095
-
Early Behavioural Markers of Disease in P301S Tau Transgenic Mice
-
20004218 1:CAS:528:DC%2BC3cXhs1altrg%3D
-
M Scattoni, et al. 2010 Early Behavioural Markers of Disease in P301S Tau Transgenic Mice Behav Brain Res 208 1 250 257 20004218 1:CAS:528: DC%2BC3cXhs1altrg%3D
-
(2010)
Behav Brain Res
, vol.208
, Issue.1
, pp. 250-257
-
-
Scattoni, M.1
-
165
-
-
58149387485
-
Apparent Behavioral Benefits of Tau Overexpression in P301L Tau Transgenic Mice
-
19096159 1:CAS:528:DC%2BD1cXhsFSmt7jK
-
D Morgan, et al. 2008 Apparent Behavioral Benefits of Tau Overexpression in P301L Tau Transgenic Mice J Alzheimers Dis 15 4 605 614 19096159 1:CAS:528:DC%2BD1cXhsFSmt7jK
-
(2008)
J Alzheimers Dis
, vol.15
, Issue.4
, pp. 605-614
-
-
Morgan, D.1
-
166
-
-
0031017541
-
Synaptic plasticity, place cells and spatial memory: Study with second generation knockouts
-
DOI 10.1016/S0166-2236(96)01023-5, PII S0166223696010235
-
MA Wilson S Tonegawa 1997 Synaptic Plasticity, Place Cells and Spatial Memory: Study with Second Generation Knockouts Trends Neurosci 20 3 102 106 9061862 1:CAS:528:DyaK2sXhsFagtLc%3D (Pubitemid 27086723)
-
(1997)
Trends in Neurosciences
, vol.20
, Issue.3
, pp. 102-106
-
-
Wilson, M.A.1
Tonegawa, S.2
-
167
-
-
0030475008
-
Impaired hippocampal representation of space in CA1-specific NMDAR1 knockout mice
-
DOI 10.1016/S0092-8674(00)81828-0
-
TJ McHugh KI Blum JZ Tsien S Tonegawa MA Wilson 1996 Impaired Hippocampal Representation of Space in CA1-specific NMDAR1 Knockout Mice Cell 87 7 1339 1349 8980239 1:CAS:528:DyaK2sXitlShtw%3D%3D (Pubitemid 27010116)
-
(1996)
Cell
, vol.87
, Issue.7
, pp. 1339-1349
-
-
McHugh, T.J.1
Blum, K.I.2
Tsien, J.Z.3
Tonegawa, S.4
Wilson, M.A.5
-
168
-
-
0030446363
-
The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory
-
DOI 10.1016/S0092-8674(00)81827-9
-
JZ Tsien PT Huerta S Tonegawa 1996 The Essential Role of hippocampal CA1 NMDA Receptor-dependent Synaptic Plasticity in Spatial Memory Cell 87 7 1327 1338 8980238 1:CAS:528:DyaK2sXitlSjuw%3D%3D (Pubitemid 27010115)
-
(1996)
Cell
, vol.87
, Issue.7
, pp. 1327-1338
-
-
Tsien, J.Z.1
Huerta, P.T.2
Tonegawa, S.3
-
169
-
-
60849136325
-
Cortical Hubs Revealed by Intrinsic Functional Connectivity: Mapping, Assessment of Stability, and Relation to Alzheimer's Disease
-
19211893 1:CAS:528:DC%2BD1MXit1Wiur0%3D
-
RL Buckner, et al. 2009 Cortical Hubs Revealed by Intrinsic Functional Connectivity: Mapping, Assessment of Stability, and Relation to Alzheimer's Disease J Neurosci 29 6 1860 1873 19211893 1:CAS:528:DC%2BD1MXit1Wiur0%3D
-
(2009)
J Neurosci
, vol.29
, Issue.6
, pp. 1860-1873
-
-
Buckner, R.L.1
-
170
-
-
0024425882
-
Optical imaging of calcium accumulation in hippocampal pyramidal cells during synaptic activation
-
DOI 10.1038/341533a0
-
WG Regehr JA Connor DW Tank 1989 Optical Imaging of Calcium Accumulation in Hippocampal Pyramidal Cells during Synaptic Activation Nature 341 6242 533 536 2797180 1:CAS:528:DyaL1MXmt12kt7Y%3D (Pubitemid 19252525)
-
(1989)
Nature
, vol.341
, Issue.6242
, pp. 533-536
-
-
Regehr, W.G.1
Connor, J.A.2
Tank, D.W.3
-
171
-
-
0035923747
-
Representation of odorants by receptor neuron input to the mouse olfactory bulb
-
DOI 10.1016/S0896-6273(01)00506-2
-
M Wachowiak LB Cohen 2001 Representation of Odorants by Receptor Neuron Input to the Mouse Olfactory Bulb Neuron 32 4 723 735 11719211 1:CAS:528:DC%2BD3MXovFOisL8%3D (Pubitemid 33145204)
-
(2001)
Neuron
, vol.32
, Issue.4
, pp. 723-735
-
-
Wachowiak, M.1
Cohen, L.B.2
-
172
-
-
0036303258
-
Facilitation at single synapses probed with optical quantal analysis
-
DOI 10.1038/nn867
-
TG Oertner BL Sabatini EA Nimchinsky K Svoboda 2002 Facilitation at Single Synapses Probed with Optical Quantal Analysis Nat Neurosci 5 7 657 664 12055631 1:CAS:528:DC%2BD38Xkslyisrc%3D (Pubitemid 34742981)
-
(2002)
Nature Neuroscience
, vol.5
, Issue.7
, pp. 657-664
-
-
Oertner, T.G.1
Sabatini, B.L.2
Nimchinsky, E.A.3
Svoboda, K.4
-
173
-
-
0035959949
-
A miniature head-mounted two-photon microscope: High-resolution brain imaging in freely moving animals
-
DOI 10.1016/S0896-6273(01)00421-4
-
F Helmchen MS Fee DW Tank W Denk 2001 A Miniature Head-mounted Two-Photon Microscope. High-resolution Brain Imaging in Freely Moving Animals Neuron 31 6 903 912 11580892 1:CAS:528:DC%2BD3MXns1Cgsrw%3D (Pubitemid 32925278)
-
(2001)
Neuron
, vol.31
, Issue.6
, pp. 903-912
-
-
Helmchen, F.1
Fee, M.S.2
Tank, D.W.3
Denk, W.4
-
174
-
-
33644551834
-
Optical Probing of Neuronal Circuit Dynamics: Genetically Encoded Versus Classical Fluorescent Sensors
-
16443289
-
T Knopfel J Diez-Garcia W Akemann 2006 Optical Probing of Neuronal Circuit Dynamics: Genetically Encoded Versus Classical Fluorescent Sensors Trends Neurosci 29 3 160 166 16443289
-
(2006)
Trends Neurosci
, vol.29
, Issue.3
, pp. 160-166
-
-
Knopfel, T.1
Diez-Garcia, J.2
Akemann, W.3
-
176
-
-
33646059907
-
Reconstruction of Firing Rate Changes Across Neuronal Populations by Temporally Deconvolved Ca2+ Imaging
-
16628208 1:CAS:528:DC%2BD28XjslSksbc%3D
-
E Yaksi RW Friedrich 2006 Reconstruction of Firing Rate Changes Across Neuronal Populations by Temporally Deconvolved Ca2+ Imaging Nat Methods 3 5 377 383 16628208 1:CAS:528:DC%2BD28XjslSksbc%3D
-
(2006)
Nat Methods
, vol.3
, Issue.5
, pp. 377-383
-
-
Yaksi, E.1
Friedrich, R.W.2
-
177
-
-
34247466096
-
Sniffing controls an adaptive filter of sensory input to the olfactory bulb
-
DOI 10.1038/nn1892, PII NN1892
-
JV Verhagen DW Wesson TI Netoff JA White M Wachowiak 2007 Sniffing Controls an Adaptive Filter of Sensory Input to the Olfactory Bulb Nat Neurosci 10 5 631 639 17450136 1:CAS:528:DC%2BD2sXksFShsbw%3D (Pubitemid 46652448)
-
(2007)
Nature Neuroscience
, vol.10
, Issue.5
, pp. 631-639
-
-
Verhagen, J.V.1
Wesson, D.W.2
Netoff, T.I.3
White, J.A.4
Wachowiak, M.5
-
178
-
-
77951623793
-
Learning-related Fine-scale Specificity Imaged in Motor Cortex Circuits of Behaving Mice
-
20376005 1:CAS:528:DC%2BC3cXktlSns74%3D
-
T Komiyama, et al. 2010 Learning-related Fine-scale Specificity Imaged in Motor Cortex Circuits of Behaving Mice Nature 464 7292 1182 1186 20376005 1:CAS:528:DC%2BC3cXktlSns74%3D
-
(2010)
Nature
, vol.464
, Issue.7292
, pp. 1182-1186
-
-
Komiyama, T.1
-
180
-
-
0019957779
-
Place navigation impaired in rats with hippocampal lesions
-
DOI 10.1038/297681a0
-
RGM Morris P Garrud JNP Rawlins J O'Keefe 1982 Place Navigation Impaired in Rats with Hippocampal Lesions Nature 297 5868 681 683 7088155 1:STN:280:DyaL383itVSguw%3D%3D (Pubitemid 12096189)
-
(1982)
Nature
, vol.297
, Issue.5868
, pp. 681-683
-
-
Morris, R.G.M.1
Garrud, P.2
Rawlins, J.N.P.3
O'Keefe, J.4
-
181
-
-
84966281067
-
How Many Ways Can Mouse Behavioral Experiments Go Wrong? Confounding Variables in Mouse Models of Neurodegenerative Diseases and How to Control Them
-
HM Schellinck DP Cyr RE Brown, et al. 2010 How Many Ways Can Mouse Behavioral Experiments Go Wrong? Confounding Variables in Mouse Models of Neurodegenerative Diseases and How to Control Them Adv Study Behav 41 255 366
-
(2010)
Adv Study Behav
, vol.41
, pp. 255-366
-
-
Schellinck, H.M.1
Cyr, D.P.2
Brown, R.E.3
-
182
-
-
0027416446
-
Mechanisms underlying induction of long-term potentiation in rat medial and lateral perforant paths in vitro
-
A Colino RC Malenka 1993 Mechanisms Underlying Induction of Long-term Potentiation in Rat Medial and Lateral Perforant Paths In vitro J Neurophysiol 69 4 1150 1159 8492154 1:CAS:528:DyaK3sXksVKitbs%3D (Pubitemid 23118815)
-
(1993)
Journal of Neurophysiology
, vol.69
, Issue.4
, pp. 1150-1159
-
-
Colino, A.1
Malenka, R.C.2
|