메뉴 건너뛰기




Volumn 15, Issue 3 SPEC. ISS., 2005, Pages 334-342

Plasticity of dendritic function

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; POTASSIUM CHANNEL; SODIUM CHANNEL;

EID: 20444410827     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.conb.2005.05.013     Document Type: Review
Times cited : (149)

References (52)
  • 1
    • 0036580846 scopus 로고    scopus 로고
    • Emerging rules for the distributions of active dendritic conductances
    • M. Migliore, and G.M. Shepherd Emerging rules for the distributions of active dendritic conductances Nat Rev Neurosci 3 2002 362 370
    • (2002) Nat Rev Neurosci , vol.3 , pp. 362-370
    • Migliore, M.1    Shepherd, G.M.2
  • 2
    • 0002151620 scopus 로고    scopus 로고
    • Voltage-gated ion channels in dendrites
    • G. Stuart N. Spruston M. Hausser Oxford University Press
    • J.C. Magee Voltage-gated ion channels in dendrites G. Stuart N. Spruston M. Hausser Dendrites 1999 Oxford University Press 139 160
    • (1999) Dendrites , pp. 139-160
    • Magee, J.C.1
  • 3
    • 0032215718 scopus 로고    scopus 로고
    • Dendritic sodium spikes are variable triggers of axonal action potentials in hippocampal CA1 pyramidal neurons
    • N.L. Golding, and N. Spruston Dendritic sodium spikes are variable triggers of axonal action potentials in hippocampal CA1 pyramidal neurons Neuron 21 1998 1189 2000
    • (1998) Neuron , vol.21 , pp. 1189-2000
    • Golding, N.L.1    Spruston, N.2
  • 4
    • 0033083763 scopus 로고    scopus 로고
    • Linear summation of excitatory inputs by CA1 pyramidal neurons
    • S. Cash, and R. Yuste Linear summation of excitatory inputs by CA1 pyramidal neurons Neuron 22 1999 383 394
    • (1999) Neuron , vol.22 , pp. 383-394
    • Cash, S.1    Yuste, R.2
  • 5
    • 0035929225 scopus 로고    scopus 로고
    • Compartmentalized and binary behavior of terminal dendrites in hippocampal pyramidal neurons
    • D.S. Wei, Y.A. Mei, A. Bagal, J.P. Kao, S.M. Thompson, and C.M. Tang Compartmentalized and binary behavior of terminal dendrites in hippocampal pyramidal neurons Science 293 2001 2272 2275
    • (2001) Science , vol.293 , pp. 2272-2275
    • Wei, D.S.1    Mei, Y.A.2    Bagal, A.3    Kao, J.P.4    Thompson, S.M.5    Tang, C.M.6
  • 6
    • 0035369079 scopus 로고    scopus 로고
    • Dendritic mechanisms underlying the coupling of the dendritic with the axonal action potential initiation zone of adult rat layer 5 pyramidal neurons
    • M.E. Larkum, J.J. Zhu, and B. Sakmann Dendritic mechanisms underlying the coupling of the dendritic with the axonal action potential initiation zone of adult rat layer 5 pyramidal neurons J Physiol 533 2001 447 466
    • (2001) J Physiol , vol.533 , pp. 447-466
    • Larkum, M.E.1    Zhu, J.J.2    Sakmann, B.3
  • 7
    • 0037468832 scopus 로고    scopus 로고
    • Pyramidal neuron as two-layer neural network
    • P. Poirazi, T. Brannon, and B.W. Mel Pyramidal neuron as two-layer neural network Neuron 37 2003 989 999 This influential study describes the ability of a detailed model pyramidal neuron to process information in either a linear or a non-linear mode depending upon the pattern of synaptic input. The model neuron summates spatio-temporally dispersed input patterns in a linear manner that enables it to respond quite accurately to fluctuations in the number of active synaptic inputs (termed 'power variation'). Conversely, the highly non-linear summation of a spatially clustered and highly synchronized input enabled the model to also respond quite accurately to alterations in the input pattern (termed 'configuration variability').
    • (2003) Neuron , vol.37 , pp. 989-999
    • Poirazi, P.1    Brannon, T.2    Mel, B.W.3
  • 9
    • 10944234870 scopus 로고    scopus 로고
    • On the initiation and propagation of dendritic spikes in CA1 pyramidal neurons
    • S. Gasparini, and J.C. Magee On the initiation and propagation of dendritic spikes in CA1 pyramidal neurons J Neurosci 24 2004 1 11
    • (2004) J Neurosci , vol.24 , pp. 1-11
    • Gasparini, S.1    Magee, J.C.2
  • 10
    • 20444365363 scopus 로고    scopus 로고
    • Input pattern dependent dendritic computation in hippocampal CA1 pyramidal neurons
    • Abstract No 737.8.
    • Gasparini S, Magee JC: Input pattern dependent dendritic computation in hippocampal CA1 pyramidal neurons [abstract]. Soc Neurosci 2004, Abstract No 737.8. This study expands on the concept of input pattern-dependent dendritic integration by showing that the unique integration modes produce distinct output modes that reflect highly divergent single cell computations (similar to the power or configuration calculations discussed above). The authors further attempt to apply these two different input-output conditions to the two major behavioral states of the hippocampus (theta and sharp-wave states).
    • (2004) Soc Neurosci
    • Gasparini, S.1    Magee, J.C.2
  • 11
    • 0041319178 scopus 로고    scopus 로고
    • Submillisecond precision of the input-output transformation function mediated by fast sodium dendritic spikes in basal dendrites of CA1 pyramidal neurons
    • G. Ariav, A. Polsky, and J. Schiller Submillisecond precision of the input-output transformation function mediated by fast sodium dendritic spikes in basal dendrites of CA1 pyramidal neurons J Neurosci 23 2003 7750 7758
    • (2003) J Neurosci , vol.23 , pp. 7750-7758
    • Ariav, G.1    Polsky, A.2    Schiller, J.3
  • 12
    • 1842682001 scopus 로고    scopus 로고
    • Dendritic control of spontaneous bursting in cerebellar Purkinje cells
    • M.D. Womack, and K. Khodakhah Dendritic control of spontaneous bursting in cerebellar Purkinje cells J Neurosci 24 2004 3511 3521
    • (2004) J Neurosci , vol.24 , pp. 3511-3521
    • Womack, M.D.1    Khodakhah, K.2
  • 13
    • 4344631919 scopus 로고    scopus 로고
    • Spatial compartmentalization and functional implications of conductance in pyramidal neurons
    • S.R. Williams Spatial compartmentalization and functional implications of conductance in pyramidal neurons Nat Neurosci 7 2004 961 967
    • (2004) Nat Neurosci , vol.7 , pp. 961-967
    • Williams, S.R.1
  • 14
    • 0033237837 scopus 로고    scopus 로고
    • h density in hippocampal CA1 neurons
    • h density in hippocampal CA1 neurons Nat Neurosci 6 1999 508 514
    • (1999) Nat Neurosci , vol.6 , pp. 508-514
    • Magee, J.C.1
  • 15
    • 0043240255 scopus 로고    scopus 로고
    • Voltage- and site-dependent control of the somatic impact of dendritic IPSPs
    • S.R. Williams, and G.J. Stuart Voltage- and site-dependent control of the somatic impact of dendritic IPSPs J Neurosci 23 2003 7358 7367
    • (2003) J Neurosci , vol.23 , pp. 7358-7367
    • Williams, S.R.1    Stuart, G.J.2
  • 16
    • 0036522018 scopus 로고    scopus 로고
    • Membrane potential bistability is controlled by the hyperpolarization- activated current I(H) in rat cerebellar Purkinje neurons in vitro
    • S.R. Williams, S.R. Christensen, G.J. Stuart, and M. Hausser Membrane potential bistability is controlled by the hyperpolarization-activated current I(H) in rat cerebellar Purkinje neurons in vitro J Physiol 539 2002 469 483
    • (2002) J Physiol , vol.539 , pp. 469-483
    • Williams, S.R.1    Christensen, S.R.2    Stuart, G.J.3    Hausser, M.4
  • 18
    • 8844278361 scopus 로고    scopus 로고
    • A behavioral role for dendritic integration: HCN1 channels constrain spatial memory and plasticity at inputs to distal dendrites of CA1 pyramidal neurons
    • •• ] represent an impressive and successful attempt to detect a functional role for H-channels in both cerebellar Purkinje and CA1 pyramidal cells through genetic deletion of HCN1, the main isoform of hyperpolarization-activated channels in these cells. They find specific motor deficits in the behaving mouse that fit well to the concept of Ih-regulation of spontaneous action potential firing in cerebellar Purkinje cells, as presented in Williams et al. [16]. In the second study the authors report that forebrain deletion of HCN1 actually improves hippocampal-dependent spatial learning, augments the power of a network level oscillation and enhances perforant path LTP. Taken together, these studies powerfully demonstrate the important role of dendritic voltage-gated ion channels and dendritic integration in behavior.
    • (2004) Cell , vol.119 , pp. 719-732
    • Nolan, M.F.1    Malleret, G.2    Dudman, J.T.3    Buhl, D.L.4    Santoro, B.5    Gibbs, E.6    Vronskaya, S.7    Buzsaki, G.8    Siegelbaum, S.A.9    Kandel, E.R.10    Morozov, A.11
  • 19
    • 0031012390 scopus 로고    scopus 로고
    • A synaptically controlled, associative signal for Hebbian plasticity in hippocampal neurons
    • J.C. Magee, and D. Johnston A synaptically controlled, associative signal for Hebbian plasticity in hippocampal neurons Science 275 1997 209 213
    • (1997) Science , vol.275 , pp. 209-213
    • Magee, J.C.1    Johnston, D.2
  • 20
    • 0035155356 scopus 로고    scopus 로고
    • Dendritic coincidence detection of EPSPs and action potentials
    • G.J. Stuart, and M. Hausser Dendritic coincidence detection of EPSPs and action potentials Nat Neurosci 4 2001 63 71
    • (2001) Nat Neurosci , vol.4 , pp. 63-71
    • Stuart, G.J.1    Hausser, M.2
  • 21
    • 0037062462 scopus 로고    scopus 로고
    • + channels contribute to spike-timing dependent long-term potentiation in hippocampal pyramidal neurons
    • + channels contribute to spike-timing dependent long-term potentiation in hippocampal pyramidal neurons Proc Natl Acad Sci USA 99 2002 8366 8371
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8366-8371
    • Watanabe, S.1    Hoffman, D.A.2    Migliore, M.3    Johnston, D.4
  • 22
    • 1242274391 scopus 로고    scopus 로고
    • 2+ signals evoked by coincident EPSPs and backpropagating action potentials in spiny stellate cells of Layer 4 in the juvenile rat somatosensory barrel cortex
    • 2+ influx on the exact timing of synaptic input and action potential output. The timing dependence of synaptic potentiation is also determined in these same cells. The striking similarity in the timing-dependencies of the two phenomena implies a mechanism for the plasticity.
    • (2004) J Neurosci , vol.24 , pp. 1689-1699
    • Nevian, T.1    Sakmann, B.2
  • 23
    • 0033860923 scopus 로고    scopus 로고
    • Competitive Hebbian learning through spike-timing-dependent synaptic plasticity
    • S. Song, K.D. Miller, and L.F. Abbott Competitive Hebbian learning through spike-timing-dependent synaptic plasticity Nat Neurosci 3 2000 919 926
    • (2000) Nat Neurosci , vol.3 , pp. 919-926
    • Song, S.1    Miller, K.D.2    Abbott, L.F.3
  • 24
    • 0037130208 scopus 로고    scopus 로고
    • Dendritic spikes as a mechanism for cooperative long-term potentiation
    • N.L. Golding, N.P. Staff, and N. Spruston Dendritic spikes as a mechanism for cooperative long-term potentiation Nature 418 2002 326 331
    • (2002) Nature , vol.418 , pp. 326-331
    • Golding, N.L.1    Staff, N.P.2    Spruston, N.3
  • 25
    • 6444225890 scopus 로고    scopus 로고
    • Single-shock LTD by local dendritic spikes in pyramidal neurons of mouse visual cortex
    • K. Holthoff, Y. Kovalchuk, R. Yuste, and A. Konnerth Single-shock LTD by local dendritic spikes in pyramidal neurons of mouse visual cortex J Physiol 560 2004 27 36 This is a second demonstration that local dendritic spikes are on their own capable of inducing long-term synaptic plasticity (see Golding et al. [24] for the first). Although this particular non-Hebbian form of synaptic plasticity was found to be present in the oblique dendrite branches of layer V neocortical neurons it is likely, particularly in light of the findings of Golding et al. [24], to extend to other inputs as well. The local spikes appear to be capable of inducing both LTP and LTD.
    • (2004) J Physiol , vol.560 , pp. 27-36
    • Holthoff, K.1    Kovalchuk, Y.2    Yuste, R.3    Konnerth, A.4
  • 26
    • 0141565148 scopus 로고    scopus 로고
    • Distance-dependent modifiable threshold for action potential back-propagation in hippocampal dendrites
    • C. Bernard, and D. Johnston Distance-dependent modifiable threshold for action potential back-propagation in hippocampal dendrites J Neurophysiol 90 2003 1807 1816
    • (2003) J Neurophysiol , vol.90 , pp. 1807-1816
    • Bernard, C.1    Johnston, D.2
  • 27
    • 0030873774 scopus 로고    scopus 로고
    • + channels underlies the activity-dependent attenuation of dendritic action potentials in hippocampal CA1 pyramidal neurons
    • + channels underlies the activity-dependent attenuation of dendritic action potentials in hippocampal CA1 pyramidal neurons J Neurosci 17 1997 6512 6521
    • (1997) J Neurosci , vol.17 , pp. 6512-6521
    • Colbert, C.M.1    Magee, J.C.2    Hoffman, D.A.3    Johnston, D.4
  • 28
    • 0032991943 scopus 로고    scopus 로고
    • Properties of slow, cumulative sodium channel inactivation in rat hippocampal CA1 pyramidal neurons
    • T. Mickus, H. Jung, and N. Spruston Properties of slow, cumulative sodium channel inactivation in rat hippocampal CA1 pyramidal neurons Biophys J 76 1999 846 860
    • (1999) Biophys J , vol.76 , pp. 846-860
    • Mickus, T.1    Jung, H.2    Spruston, N.3
  • 29
    • 0032587439 scopus 로고    scopus 로고
    • Modulation of backpropagating action potentials in dendrites of hippocampal pyramidal neurons
    • D. Johnston, D. Hoffman, C. Colbert, and J.C. Magee Modulation of backpropagating action potentials in dendrites of hippocampal pyramidal neurons Curr Opin Neurobiol 9 1999 288 292
    • (1999) Curr Opin Neurobiol , vol.9 , pp. 288-292
    • Johnston, D.1    Hoffman, D.2    Colbert, C.3    Magee, J.C.4
  • 30
    • 0034966340 scopus 로고    scopus 로고
    • Control of Na+ spike backpropagation by intracellular signaling in the pyramidal neuron dendrites
    • H. Tsubokawa Control of Na+ spike backpropagation by intracellular signaling in the pyramidal neuron dendrites Mol Neurobiol 22 2000 129 141
    • (2000) Mol Neurobiol , vol.22 , pp. 129-141
    • Tsubokawa, H.1
  • 31
    • 0036178384 scopus 로고    scopus 로고
    • The other half of Hebb: K+ channels and the regulation of neuronal excitability in the hippocampus
    • L.A. Schrader, A.E. Anderson, A.W. Varga, M. Levy, and J.D. Sweatt The other half of Hebb: K+ channels and the regulation of neuronal excitability in the hippocampus Mol Neurobiol 25 2002 51 66
    • (2002) Mol Neurobiol , vol.25 , pp. 51-66
    • Schrader, L.A.1    Anderson, A.E.2    Varga, A.W.3    Levy, M.4    Sweatt, J.D.5
  • 32
    • 0036976524 scopus 로고    scopus 로고
    • Differential modulation of I(h) by 5-HT receptors in mouse CA1 hippocampal neurons
    • U. Bickmeyer, M. Heine, T. Manzke, and D.W. Richter Differential modulation of I(h) by 5-HT receptors in mouse CA1 hippocampal neurons Eur J Neurosci 16 2002 209 218
    • (2002) Eur J Neurosci , vol.16 , pp. 209-218
    • Bickmeyer, U.1    Heine, M.2    Manzke, T.3    Richter, D.W.4
  • 33
    • 0041379310 scopus 로고    scopus 로고
    • Transmitter modulation of slow, activity-dependent alterations in Na channel availability endows neurons with a novel form of cellular plasticity
    • D.B. Carr, M. Day, A.R. Cantrell, J. Held, T. Scheuer, W.A. Catterall, and D.J. Surmeier Transmitter modulation of slow, activity-dependent alterations in Na channel availability endows neurons with a novel form of cellular plasticity Neuron 39 2003 793 806
    • (2003) Neuron , vol.39 , pp. 793-806
    • Carr, D.B.1    Day, M.2    Cantrell, A.R.3    Held, J.4    Scheuer, T.5    Catterall, W.A.6    Surmeier, D.J.7
  • 34
    • 0242300203 scopus 로고    scopus 로고
    • The other side of the engram: Experience-driven changes in neuronal intrinsic excitability
    • W. Zhang, and D.J. Linden The other side of the engram: experience-driven changes in neuronal intrinsic excitability Nat Rev Neurosci 4 2003 885 900
    • (2003) Nat Rev Neurosci , vol.4 , pp. 885-900
    • Zhang, W.1    Linden, D.J.2
  • 35
    • 2942550646 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in synaptic plasticity and memory
    • J.D. Sweatt Mitogen-activated protein kinases in synaptic plasticity and memory Curr Opin Neurobiol 14 2004 311 317
    • (2004) Curr Opin Neurobiol , vol.14 , pp. 311-317
    • Sweatt, J.D.1
  • 36
    • 0029822574 scopus 로고    scopus 로고
    • Trace eyeblink conditioning increases CA1 excitability in a transient and learning-specific manner
    • J.R. Moyer, L.T. Thompson, and J.F. Disteroft Trace eyeblink conditioning increases CA1 excitability in a transient and learning-specific manner J Neurosci 16 1996 5536 5546
    • (1996) J Neurosci , vol.16 , pp. 5536-5546
    • Moyer, J.R.1    Thompson, L.T.2    Disteroft, J.F.3
  • 37
    • 0034004553 scopus 로고    scopus 로고
    • Rapid synaptically driven increases in the intrinsic excitability of cerebellar deep nuclear neurons
    • C.D. Aizenman, and D.J. Linden Rapid synaptically driven increases in the intrinsic excitability of cerebellar deep nuclear neurons Nat Neurosci 3 2000 109 111
    • (2000) Nat Neurosci , vol.3 , pp. 109-111
    • Aizenman, C.D.1    Linden, D.J.2
  • 38
    • 1642580920 scopus 로고    scopus 로고
    • Long-term potentiation is accompanied by an enhanced local excitability of pyramidal neuron dendrites
    • A. Frick, J.C. Magee, and D. Johnston Long-term potentiation is accompanied by an enhanced local excitability of pyramidal neuron dendrites Nat Neurosci 7 2004 126 132 One of the first characterizations of long-lasting channel modulations produced by LTP-inducing stimuli. The authors show that theta-patterned stimulation induces both a long-term potentiation of synaptic weight and a reduction in the amount of available transient outward current in a dendritic region near the synaptic input. This reduction is the result of a hyperpolarized shift in the voltage-dependence of steady-state inactivation and leads to an elevation in the general membrane excitability of the affected dendrite.
    • (2004) Nat Neurosci , vol.7 , pp. 126-132
    • Frick, A.1    Magee, J.C.2    Johnston, D.3
  • 39
    • 0037421670 scopus 로고    scopus 로고
    • Bidirectional changes in spatial dendritic integration accompanying long-term synaptic modifications
    • Z. Wang, N.-L. Xu, C. Wu, S. Duan, and M.-M. Poo Bidirectional changes in spatial dendritic integration accompanying long-term synaptic modifications Neuron 37 2003 463 472
    • (2003) Neuron , vol.37 , pp. 463-472
    • Wang, Z.1    Xu, N.-L.2    Wu, C.3    Duan, S.4    Poo, M.-M.5
  • 40
    • 0042861385 scopus 로고    scopus 로고
    • Plasticity of calcium channels in dendritic spines
    • R. Yasuda, B.L. Sabatini, and K. Svoboda Plasticity of calcium channels in dendritic spines Nat Neurosci 6 2003 948 955
    • (2003) Nat Neurosci , vol.6 , pp. 948-955
    • Yasuda, R.1    Sabatini, B.L.2    Svoboda, K.3
  • 41
    • 1842534335 scopus 로고    scopus 로고
    • Functional conversion between A-type and delayed rectifier K+ channels by membrane lipids
    • D. Oliver, C.C. Lien, M. Soom, T. Baukrowitz, P. Jonas, and B. Fakler Functional conversion between A-type and delayed rectifier K+ channels by membrane lipids Science 304 2004 265 270 An outstanding study that thoroughly characterizes a truly remarkable channel 'modulation' produced by lipid signaling molecules. The authors show that the inactivation properties of recombinant and native K+ channels can be converted from transient to sustained and vice versa following application of phosphoinositides and arachidonic acid. This long-term conversion was so profound that it changed the action potential profile of a set of interneurons from fast spiking to slow adaptive firing.
    • (2004) Science , vol.304 , pp. 265-270
    • Oliver, D.1    Lien, C.C.2    Soom, M.3    Baukrowitz, T.4    Jonas, P.5    Fakler, B.6
  • 42
    • 0037407956 scopus 로고    scopus 로고
    • Dopamine-dependent facilitation of LTP induction in hippocampal CA1 by exposure to spatial novelty
    • S. Li, W.K. Cullen, R. Anwyl, and M.J. Rowan Dopamine-dependent facilitation of LTP induction in hippocampal CA1 by exposure to spatial novelty Nat Neurosci 6 2003 526 531
    • (2003) Nat Neurosci , vol.6 , pp. 526-531
    • Li, S.1    Cullen, W.K.2    Anwyl, R.3    Rowan, M.J.4
  • 43
    • 3142693811 scopus 로고    scopus 로고
    • Increased attention to spatial context increases both place field stability and spatial memory
    • C.G. Kentros, N.T. Agnihotri, S. Streater, R.D. Hawkins, and E.R. Kandel Increased attention to spatial context increases both place field stability and spatial memory Neuron 42 2004 283 295
    • (2004) Neuron , vol.42 , pp. 283-295
    • Kentros, C.G.1    Agnihotri, N.T.2    Streater, S.3    Hawkins, R.D.4    Kandel, E.R.5
  • 45
    • 0142244116 scopus 로고    scopus 로고
    • Sleep deprivation reduces synaptic plasticity and membrane excitability in hippocampal neurons
    • C. McDermott, G. LaHoste, C. Chen, N.G. Bazan, and J.C. Magee Sleep deprivation reduces synaptic plasticity and membrane excitability in hippocampal neurons J Neurosci 23 2003 9687 9695
    • (2003) J Neurosci , vol.23 , pp. 9687-9695
    • McDermott, C.1    Lahoste, G.2    Chen, C.3    Bazan, N.G.4    Magee, J.C.5
  • 47
    • 0035102720 scopus 로고    scopus 로고
    • Persistently modified h-channels after complex febrile seizures convert the seizure-induced enhancement of inhibition to hyperexcitability
    • K. Chen, I. Aradi, N. Thon, M. Eghbal-Ahmadi, T.Z. Baram, and I. Soltesz Persistently modified h-channels after complex febrile seizures convert the seizure-induced enhancement of inhibition to hyperexcitability Nat Med 7 2001 331 337
    • (2001) Nat Med , vol.7 , pp. 331-337
    • Chen, K.1    Aradi, I.2    Thon, N.3    Eghbal-Ahmadi, M.4    Baram, T.Z.5    Soltesz, I.6
  • 48
    • 7044222366 scopus 로고    scopus 로고
    • Seizure-induced plasticity of h channels in entorhinal cortical Layer III pyramidal neurons
    • M.M. Shah, A.E. Anderson, V. Leung, X. Lin, and D. Johnston Seizure-induced plasticity of h channels in entorhinal cortical Layer III pyramidal neurons Neuron 44 2004 495 508 This study represents one of several reports of persistent channel modifications in neurons that are associated with a specific pathological situation (see Chen et al. [47] in particular). The authors report a significant decline in hyperpolarization-activated current and HCN1 and HCN2 expression in neurons of the entorhinal cortex 1 week following seizure induction. Such a change leads to an increase in dendritic excitability and as such might be involved in establishing the form of epilepsy found in these animals.
    • (2004) Neuron , vol.44 , pp. 495-508
    • Shah, M.M.1    Anderson, A.E.2    Leung, V.3    Lin, X.4    Johnston, D.5
  • 49
    • 1842681997 scopus 로고    scopus 로고
    • Calcium-calmodulin-dependent kinase II modulates Kv4.2 channel expression and upregulates neuronal A-type potassium currents
    • A.W. Varga, L.L. Yuan, A.E. Anderson, L.A. Schrader, G.Y. Wu, J.R. Gatchel, D. Johnston, and J.D. Sweatt Calcium-calmodulin-dependent kinase II modulates Kv4.2 channel expression and upregulates neuronal A-type potassium currents J Neurosci 24 2004 3643 3654
    • (2004) J Neurosci , vol.24 , pp. 3643-3654
    • Varga, A.W.1    Yuan, L.L.2    Anderson, A.E.3    Schrader, L.A.4    Wu, G.Y.5    Gatchel, J.R.6    Johnston, D.7    Sweatt, J.D.8
  • 50
    • 0033360297 scopus 로고    scopus 로고
    • Plasticity in the intrinsic excitability of cortical pyramidal neurons
    • N.S. Desai, L.C. Rutherford, and G.G. Turrigiano Plasticity in the intrinsic excitability of cortical pyramidal neurons Nat Neurosci 2 1999 515 520
    • (1999) Nat Neurosci , vol.2 , pp. 515-520
    • Desai, N.S.1    Rutherford, L.C.2    Turrigiano, G.G.3
  • 51
    • 0141918785 scopus 로고    scopus 로고
    • Compartmentalized synthesis and degradation of protein in neurons
    • O. Steward, and E.M. Schuman Compartmentalized synthesis and degradation of protein in neurons Neuron 40 2003 347 359
    • (2003) Neuron , vol.40 , pp. 347-359
    • Steward, O.1    Schuman, E.M.2
  • 52
    • 3042521496 scopus 로고    scopus 로고
    • Regulation of dendritic protein synthesis by miniature synaptic events
    • M.A. Sutton, N.R. Wall, G. Aakalu, and E.M. Schuman Regulation of dendritic protein synthesis by miniature synaptic events Science 304 2004 1979 1983 In this study, the authors demonstrate a role for spontaneous synaptic events (minis) in the regulation of local dendrite protein synthesis. They show that in cultured hippocampal neurons, blockade of glutamate receptors for >10 h increases dendritic protein synthesis, whereas increasing mini frequency leads to significant reductions in less than 2 h. These data hint at a novel mechanism for the regulation of translation machinery in neuronal dendrites.
    • (2004) Science , vol.304 , pp. 1979-1983
    • Sutton, M.A.1    Wall, N.R.2    Aakalu, G.3    Schuman, E.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.