메뉴 건너뛰기




Volumn 3, Issue 5, 2011, Pages 586-612

CD4 +T cell depletion in human immunodeficiency virus (HIV) infection: Role of apoptosis

Author keywords

Apoptosis; HIV; Viral proteins

Indexed keywords

CD4 ANTIGEN; CD45RA ANTIGEN; CD45RO ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE; INTERLEUKIN 17; INTERLEUKIN 2 RECEPTOR ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; NEF PROTEIN; TRANSACTIVATOR PROTEIN; VIRUS ENVELOPE PROTEIN; VPR PROTEIN;

EID: 79957880451     PISSN: None     EISSN: 19994915     Source Type: Journal    
DOI: 10.3390/v3050586     Document Type: Review
Times cited : (110)

References (173)
  • 1
    • 0036791348 scopus 로고    scopus 로고
    • How death shapes life during development
    • Baehrecke, E.H. How death shapes life during development. Nat. Rev. Mol. Cell Biol. 2002, 3, 779-787.
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 779-787
    • Baehrecke, E.H.1
  • 2
    • 70549107710 scopus 로고    scopus 로고
    • Mitochondrial cell death effectors
    • Brenner, D.; Mak, T.W. Mitochondrial cell death effectors. Curr. Opin. Cell Biol. 2009, 21, 871-877.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 871-877
    • Brenner, D.1    Mak, T.W.2
  • 3
    • 60149085396 scopus 로고    scopus 로고
    • The many roles of FAS receptor signaling in the immune system
    • Strasser, A.; Jost, P.J.; Nagata, S. The many roles of FAS receptor signaling in the immune system. Immunity 2009, 30, 180-192.
    • (2009) Immunity , vol.30 , pp. 180-192
    • Strasser, A.1    Jost, P.J.2    Nagata, S.3
  • 4
    • 65449152836 scopus 로고    scopus 로고
    • Following TRAIL's path in the immune system
    • Falschlehner, C.; Schaefer, U.; Walczak, H. Following TRAIL's path in the immune system. Immunology 2009, 127, 145-154.
    • (2009) Immunology , vol.127 , pp. 145-154
    • Falschlehner, C.1    Schaefer, U.2    Walczak, H.3
  • 6
    • 77951214016 scopus 로고    scopus 로고
    • Mammalian autophagy: Core molecular machinery and signaling regulation
    • Yang, Z.; Klionsky, D.J. Mammalian autophagy: core molecular machinery and signaling regulation. Curr. Opin. Cell Biol. 2010, 22, 124-131.
    • (2010) Curr. Opin. Cell Biol. , vol.22 , pp. 124-131
    • Yang, Z.1    Klionsky, D.J.2
  • 7
    • 67549142261 scopus 로고    scopus 로고
    • Life and death partners: Apoptosis, autophagy and the cross-talk between them
    • Eisenberg-Lerner, A.; Bialik, S.; Simon, H.U.; Kimchi, A. Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell Death Differ. 2009, 16, 966-975.
    • (2009) Cell Death Differ , vol.16 , pp. 966-975
    • Eisenberg-Lerner, A.1    Bialik, S.2    Simon, H.U.3    Kimchi, A.4
  • 8
    • 42449123761 scopus 로고    scopus 로고
    • Expansion and evolution of cell death programmes
    • Degterev, A.; Yuan, J. Expansion and evolution of cell death programmes. Nat. Rev. Mol. Cell Biol. 2008, 9, 378-390.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 378-390
    • Degterev, A.1    Yuan, J.2
  • 9
    • 0037833695 scopus 로고    scopus 로고
    • The role of CD95 in the regulation of peripheral T-cell apoptosis
    • Krueger, A.; Fas, S.C.; Baumann, S.; Krammer, P.H. The role of CD95 in the regulation of peripheral T-cell apoptosis. Immunol. Rev. 2003, 193, 58-69.
    • (2003) Immunol. Rev. , vol.193 , pp. 58-69
    • Krueger, A.1    Fas, S.C.2    Baumann, S.3    Krammer, P.H.4
  • 10
    • 0038171458 scopus 로고    scopus 로고
    • Activation-induced cell death in T cells
    • Green, D.R.; Droin, N.; Pinkoski, M. Activation-induced cell death in T cells. Immunol. Rev. 2003, 193, 70-81.
    • (2003) Immunol. Rev. , vol.193 , pp. 70-81
    • Green, D.R.1    Droin, N.2    Pinkoski, M.3
  • 11
    • 33646038349 scopus 로고    scopus 로고
    • Activation-induced cell death in T cells and autoimmunity
    • Zhang, J.; Xu, X.; Liu, Y. Activation-induced cell death in T cells and autoimmunity. Cell. Mol. Immunol. 2004, 1, 186-192.
    • (2004) Cell. Mol. Immunol. , vol.1 , pp. 186-192
    • Zhang, J.1    Xu, X.2    Liu, Y.3
  • 13
    • 77950475296 scopus 로고    scopus 로고
    • To kill or be killed: How viruses interact with the cell death machinery
    • Kaminskyy, V.; Zhivotovsky, B. To kill or be killed: how viruses interact with the cell death machinery. J. Intern. Med. 2010, 267, 473-482.
    • (2010) J. Intern. Med. , vol.267 , pp. 473-482
    • Kaminskyy, V.1    Zhivotovsky, B.2
  • 14
    • 79957888573 scopus 로고    scopus 로고
    • Mechanisms of HIV-associated lymphocyte apoptosis: 2010
    • Cummins, N.W.; Badley, A.D. Mechanisms of HIV-associated lymphocyte apoptosis: 2010. Cell Death Dis. 2010, 1, e99.
    • (2010) Cell Death Dis , vol.1
    • Cummins, N.W.1    Badley, A.D.2
  • 15
  • 17
    • 0034906440 scopus 로고    scopus 로고
    • An overview of the determinants of CCR5 and CXCR4 co-receptor function
    • Dragic, T. An overview of the determinants of CCR5 and CXCR4 co-receptor function. J. Gen. Virol. 2001, 82, 1807-1814.
    • (2001) J. Gen. Virol. , vol.82 , pp. 1807-1814
    • Dragic, T.1
  • 18
    • 0033012398 scopus 로고    scopus 로고
    • Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
    • Berger, E.A.; Murphy, P.M.; Farber, J.M. Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. Annu. Rev. Immunol. 1999, 17, 657-700.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 657-700
    • Berger, E.A.1    Murphy, P.M.2    Farber, J.M.3
  • 20
    • 0022546877 scopus 로고
    • AIDS retrovirus induced cytopathology: Giant cell formation and involvement of CD4 antigen
    • Lifson, J.D.; Reyes, G.R.; McGrath, M.S.; Stein, B.S.; Engleman, E.G., AIDS retrovirus induced cytopathology: giant cell formation and involvement of CD4 antigen. Science 1986, 232, 1123-1127.
    • (1986) Science , vol.232 , pp. 1123-1127
    • Lifson, J.D.1    Reyes, G.R.2    McGrath, M.S.3    Stein, B.S.4    Engleman, E.G.5
  • 21
    • 0024366737 scopus 로고
    • Regulatory pathways governing HIV-1 replication
    • Cullen, B.R.; Greene, W.C. Regulatory pathways governing HIV-1 replication. Cell 1989, 58, 423-426.
    • (1989) Cell , vol.58 , pp. 423-426
    • Cullen, B.R.1    Greene, W.C.2
  • 23
    • 4644289983 scopus 로고    scopus 로고
    • Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract
    • Mehandru, S.; Poles, M.A.; Tenner-Racz, K.; Horowitz, A.; Hurley, A.; Hogan, C.; Boden, D.; Racz, P.; Markowitz, M. Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract. J. Exp. Med. 2004, 200, 761-770.
    • (2004) J. Exp. Med. , vol.200 , pp. 761-770
    • Mehandru, S.1    Poles, M.A.2    Tenner-Racz, K.3    Horowitz, A.4    Hurley, A.5    Hogan, C.6    Boden, D.7    Racz, P.8    Markowitz, M.9
  • 24
    • 33644822414 scopus 로고    scopus 로고
    • Pathogenesis of HIV infection: What the virus spares is as important as what it destroys
    • Grossman, Z.; Meier-Schellersheim, M.; Paul, W. E.; Picker, L.J. Pathogenesis of HIV infection: what the virus spares is as important as what it destroys. Nat. Med. 2006, 12, 289-295.
    • (2006) Nat. Med. , vol.12 , pp. 289-295
    • Grossman, Z.1    Meier-Schellersheim, M.2    Paul, W.E.3    Picker, L.J.4
  • 30
    • 77950531446 scopus 로고    scopus 로고
    • HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs
    • Carter, C.C.; Onafuwa-Nuga, A.; McNamara, L.A.; Riddell, J.T.; Bixby, D.; Savona, M.R.; Collins, K.L. HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs. Nat. Med. 2010, 16, 446-451.
    • (2010) Nat. Med. , vol.16 , pp. 446-451
    • Carter, C.C.1    Onafuwa-Nuga, A.2    McNamara, L.A.3    Riddell, J.T.4    Bixby, D.5    Savona, M.R.6    Collins, K.L.7
  • 31
    • 0030860537 scopus 로고    scopus 로고
    • Macrophages as a source of HIV during opportunistic infections
    • Orenstein, J.M.; Fox, C.; Wahl, S.M. Macrophages as a source of HIV during opportunistic infections. Science 1997, 276, 1857-1861.
    • (1997) Science , vol.276 , pp. 1857-1861
    • Orenstein, J.M.1    Fox, C.2    Wahl, S.M.3
  • 33
    • 79957921699 scopus 로고    scopus 로고
    • Up-Regulation of TLR2 and TLR4 in Dendritic Cells in Response to HIV Type 1 and Coinfection with Opportunistic Pathogens
    • doi:10.1089/aid.2010.0302
    • Hernandez, J.C.; Arteaga, J.; Paul, S.; Kumar, A.; Latz, E.; Urcuqui-Inchima, S. Up-Regulation of TLR2 and TLR4 in Dendritic Cells in Response to HIV Type 1 and Coinfection with Opportunistic Pathogens AIDS Res. Hum. Retroviruses. 2011, 27, doi:10.1089/aid.2010.0302.
    • (2011) AIDS Res. Hum. Retroviruses , pp. 27
    • Hernandez, J.C.1    Arteaga, J.2    Paul, S.3    Kumar, A.4    Latz, E.5    Urcuqui-Inchima, S.6
  • 35
    • 33645924682 scopus 로고    scopus 로고
    • HIV disease: Fallout from a mucosal catastrophe?
    • Brenchley, J.M.; Price, D.A.; Douek, D.C. HIV disease: Fallout from a mucosal catastrophe? Nat. Immunol. 2006, 7, 235-239.
    • (2006) Nat. Immunol. , vol.7 , pp. 235-239
    • Brenchley, J.M.1    Price, D.A.2    Douek, D.C.3
  • 36
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann, T.R.; Cherwinski, H.; Bond, M.W.; Giedlin, M.A.; Coffman, R.L. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 1986, 136, 2348-2357.
    • (1986) J. Immunol. , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 37
    • 52649167708 scopus 로고    scopus 로고
    • CD4 T cells: Fates, functions, and faults
    • Zhu, J.; Paul, W.E. CD4 T cells: fates, functions, and faults. Blood 2008, 112, 1557-1569.
    • (2008) Blood , vol.112 , pp. 1557-1569
    • Zhu, J.1    Paul, W.E.2
  • 38
    • 33845605046 scopus 로고    scopus 로고
    • Lymphocyte numbers and subsets in the human blood. Do they mirror the situation in all organs
    • Blum, K.S.; Pabst, R. Lymphocyte numbers and subsets in the human blood. Do they mirror the situation in all organs? Immunol. Lett. 2007, 108, 45-51.
    • (2007) Immunol. Lett. , vol.108 , pp. 45-51
    • Blum, K.S.1    Pabst, R.2
  • 39
    • 42749086113 scopus 로고    scopus 로고
    • Tissue distribution of lymphocytes and plasma cells and the role of the gut
    • author reply 209-210
    • Pabst, R.; Russell, M.W.; Brandtzaeg, P. Tissue distribution of lymphocytes and plasma cells and the role of the gut. Trends. Immunol. 2008, 29, 206-208; author reply 209-210.
    • (2008) Trends. Immunol. , vol.29 , pp. 206-208
    • Pabst, R.1    Russell, M.W.2    Brandtzaeg, P.3
  • 41
    • 0034001778 scopus 로고    scopus 로고
    • Human intestinal lamina propria and intraepithelial lymphocytes express receptors specific for chemokines induced by inflammation
    • Agace, W.W.; Roberts, A.I.; Wu, L.; Greineder, C.; Ebert, E.C.; Parker, C.M. Human intestinal lamina propria and intraepithelial lymphocytes express receptors specific for chemokines induced by inflammation. Eur. J. Immunol. 2000, 30, 819-826.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 819-826
    • Agace, W.W.1    Roberts, A.I.2    Wu, L.3    Greineder, C.4    Ebert, E.C.5    Parker, C.M.6
  • 42
    • 0034888099 scopus 로고    scopus 로고
    • A preponderance of CCR5(+) CXCR4(+) mononuclear cells enhances gastrointestinal mucosal susceptibility to human immunodeficiency virus type 1 infection
    • Poles, M.A.; Elliott, J.; Taing, P.; Anton, P.A.; Chen, I.S. A preponderance of CCR5(+) CXCR4(+) mononuclear cells enhances gastrointestinal mucosal susceptibility to human immunodeficiency virus type 1 infection. J. Virol. 2001, 75, 8390-8399.
    • (2001) J. Virol. , vol.75 , pp. 8390-8399
    • Poles, M.A.1    Elliott, J.2    Taing, P.3    Anton, P.A.4    Chen, I.S.5
  • 43
    • 77952313777 scopus 로고    scopus 로고
    • Differentiation of effector CD4 T cell populations (*)
    • Zhu, J.; Yamane, H.; Paul, W.E. Differentiation of effector CD4 T cell populations (*). Annu. Rev. Immunol. 2010, 28, 445-489.
    • (2010) Annu. Rev. Immunol. , vol.28 , pp. 445-489
    • Zhu, J.1    Yamane, H.2    Paul, W.E.3
  • 44
    • 40449111457 scopus 로고    scopus 로고
    • Human Th17 cells share major trafficking receptors with both polarized effector T cells and FOXP3+ regulatory T cells
    • Lim, H.W.; Lee, J.; Hillsamer, P.; Kim, C.H. Human Th17 cells share major trafficking receptors with both polarized effector T cells and FOXP3+ regulatory T cells. J. Immunol. 2008, 180, 122-129.
    • (2008) J. Immunol. , vol.180 , pp. 122-129
    • Lim, H.W.1    Lee, J.2    Hillsamer, P.3    Kim, C.H.4
  • 47
    • 45749101727 scopus 로고    scopus 로고
    • Induction and effector functions of T(H)17 cells
    • Bettelli, E.; Korn, T.; Oukka, M.; Kuchroo, V.K. Induction and effector functions of T(H)17 cells. Nature 2008, 453, 1051-1057.
    • (2008) Nature , vol.453 , pp. 1051-1057
    • Bettelli, E.1    Korn, T.2    Oukka, M.3    Kuchroo, V.K.4
  • 49
    • 34748873441 scopus 로고    scopus 로고
    • Regulatory T cells and infection: A dangerous necessity
    • Belkaid, Y. Regulatory T cells and infection: a dangerous necessity. Nat. Rev. Immunol. 2007, 7, 875-888.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 875-888
    • Belkaid, Y.1
  • 51
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot, J.D.; Gavin, M.A.; Rudensky, A.Y. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 2003, 4, 330-336.
    • (2003) Nat. Immunol. , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 52
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori, S.; Nomura, T.; Sakaguchi, S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003, 299, 1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 55
    • 0034716925 scopus 로고    scopus 로고
    • Regulatory T cells: Key controllers of immunologic self-tolerance
    • Sakaguchi, S. Regulatory T cells: key controllers of immunologic self-tolerance. Cell 2000, 101, 455-458.
    • (2000) Cell , vol.101 , pp. 455-458
    • Sakaguchi, S.1
  • 56
    • 65549123867 scopus 로고    scopus 로고
    • Natural and adaptive foxp3+ regulatory T cells: More of the same or a division of labor?
    • Curotto de Lafaille, M.A.; Lafaille, J.J. Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor? Immunity 2009, 30, 626-635.
    • (2009) Immunity , vol.30 , pp. 626-635
    • Curotto de Lafaille, M.A.1    Lafaille, J.J.2
  • 57
    • 0036345337 scopus 로고    scopus 로고
    • Origin of regulatory T cells with known specificity for antigen
    • Apostolou, I.; Sarukhan, A.; Klein, L.; von Boehmer, H. Origin of regulatory T cells with known specificity for antigen. Nat. Immunol. 2002, 3, 756-763.
    • (2002) Nat. Immunol. , vol.3 , pp. 756-763
    • Apostolou, I.1    Sarukhan, A.2    Klein, L.3    von Boehmer, H.4
  • 58
    • 2542420993 scopus 로고    scopus 로고
    • In vivo instruction of suppressor commitment in naive T cells
    • Apostolou, I.; von Boehmer, H. In vivo instruction of suppressor commitment in naive T cells. J. Exp. Med. 2004, 199, 1401-1408.
    • (2004) J. Exp. Med. , vol.199 , pp. 1401-1408
    • Apostolou, I.1    von Boehmer, H.2
  • 61
    • 34248382192 scopus 로고    scopus 로고
    • T regulatory cells and HIV infection
    • Sempere, J.M.; Soriano, V.; Benito, J.M. T regulatory cells and HIV infection. AIDS Rev. 2007, 9, 54-60.
    • (2007) AIDS Rev , vol.9 , pp. 54-60
    • Sempere, J.M.1    Soriano, V.2    Benito, J.M.3
  • 62
    • 77954948735 scopus 로고    scopus 로고
    • Effector T cell plasticity: Flexibility in the face of changing circumstances
    • Murphy, K.M.; Stockinger, B. Effector T cell plasticity: flexibility in the face of changing circumstances. Nat. Immunol. 2010, 11, 674-680.
    • (2010) Nat. Immunol. , vol.11 , pp. 674-680
    • Murphy, K.M.1    Stockinger, B.2
  • 63
    • 67651154105 scopus 로고    scopus 로고
    • Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells
    • Duhen, T.; Geiger, R.; Jarrossay, D.; Lanzavecchia, A.; Sallusto, F. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat. Immunol. 2009, 10, 857-863.
    • (2009) Nat. Immunol. , vol.10 , pp. 857-863
    • Duhen, T.1    Geiger, R.2    Jarrossay, D.3    Lanzavecchia, A.4    Sallusto, F.5
  • 64
    • 67651171182 scopus 로고    scopus 로고
    • Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells
    • Trifari, S.; Kaplan, C.D.; Tran, E.H.; Crellin, N.K.; Spits, H. Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells. Nat. Immunol. 2009, 10, 864-871.
    • (2009) Nat. Immunol. , vol.10 , pp. 864-871
    • Trifari, S.1    Kaplan, C.D.2    Tran, E.H.3    Crellin, N.K.4    Spits, H.5
  • 65
    • 0142092389 scopus 로고    scopus 로고
    • Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy
    • Guadalupe, M.; Reay, E.; Sankaran, S.; Prindiville, T.; Flamm, J.; McNeil, A.; Dandekar, S. Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy. J. Virol. 2003, 77, 11708-11717.
    • (2003) J. Virol. , vol.77 , pp. 11708-11717
    • Guadalupe, M.1    Reay, E.2    Sankaran, S.3    Prindiville, T.4    Flamm, J.5    McNeil, A.6    Dandekar, S.7
  • 68
    • 33745363316 scopus 로고    scopus 로고
    • Immunopathogenesis of acute AIDS virus infection
    • Picker, L.J. Immunopathogenesis of acute AIDS virus infection. Curr. Opin. Immunol. 2006, 18, 399-405.
    • (2006) Curr. Opin. Immunol. , vol.18 , pp. 399-405
    • Picker, L.J.1
  • 69
    • 0028839280 scopus 로고
    • T helper type 1/T helper type 2 cytokines and T cell death: Preventive effect of interleukin 12 on activation-induced and CD95 (FAS/APO-1)-mediated apoptosis of CD4+ T cells from human immunodeficiency virus-infected persons
    • Estaquier, J.; Idziorek, T.; Zou, W.; Emilie, D.; Farber, C.M.; Bourez, J.M.; Ameisen, J.C. T helper type 1/T helper type 2 cytokines and T cell death: preventive effect of interleukin 12 on activation-induced and CD95 (FAS/APO-1)-mediated apoptosis of CD4+ T cells from human immunodeficiency virus-infected persons. J. Exp. Med. 1995, 182, 1759-1767.
    • (1995) J. Exp. Med. , vol.182 , pp. 1759-1767
    • Estaquier, J.1    Idziorek, T.2    Zou, W.3    Emilie, D.4    Farber, C.M.5    Bourez, J.M.6    Ameisen, J.C.7
  • 72
    • 0035714449 scopus 로고    scopus 로고
    • Both age and gender affect thymic output: More recent thymic migrants in females than males as they age
    • Pido-Lopez, J.; Imami, N.; Aspinall, R. Both age and gender affect thymic output: more recent thymic migrants in females than males as they age. Clin. Exp. Immunol. 2001, 125, 409-413.
    • (2001) Clin. Exp. Immunol. , vol.125 , pp. 409-413
    • Pido-Lopez, J.1    Imami, N.2    Aspinall, R.3
  • 75
    • 0036493726 scopus 로고    scopus 로고
    • Increased sensitivity of T lymphocytes to tumor necrosis factor receptor 1 (TNFR1)- and TNFR2-mediated apoptosis in HIV infection: Relation to expression of Bcl-2 and active caspase-8 and caspase-3
    • de Oliveira Pinto, L.M.; Garcia, S.; Lecoeur, H.; Rapp, C.; Gougeon, M.L. Increased sensitivity of T lymphocytes to tumor necrosis factor receptor 1 (TNFR1)- and TNFR2-mediated apoptosis in HIV infection: relation to expression of Bcl-2 and active caspase-8 and caspase-3. Blood 2002, 99, 1666-1675.
    • (2002) Blood , vol.99 , pp. 1666-1675
    • de Oliveira Pinto, L.M.1    Garcia, S.2    Lecoeur, H.3    Rapp, C.4    Gougeon, M.L.5
  • 76
    • 15244358107 scopus 로고    scopus 로고
    • TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected patients and its in vitro production by antigen-presenting cells
    • Herbeuval, J.P.; Boasso, A.; Grivel, J.C.; Hardy, A.W.; Anderson, S.A.; Dolan, M.J.; Chougnet, C.; Lifson, J.D.; Shearer, G.M. TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected patients and its in vitro production by antigen-presenting cells. Blood 2005, 105, 2458-2464.
    • (2005) Blood , vol.105 , pp. 2458-2464
    • Herbeuval, J.P.1    Boasso, A.2    Grivel, J.C.3    Hardy, A.W.4    Anderson, S.A.5    Dolan, M.J.6    Chougnet, C.7    Lifson, J.D.8    Shearer, G.M.9
  • 77
    • 4644277015 scopus 로고    scopus 로고
    • Apoptosis of bystander T cells induced by human immunodeficiency virus type 1 with increased envelope/receptor affinity and coreceptor binding site exposure
    • Holm, G.H.; Zhang, C.; Gorry, P.R.; Peden, K.; Schols, D.; De Clercq, E.; Gabuzda, D. Apoptosis of bystander T cells induced by human immunodeficiency virus type 1 with increased envelope/receptor affinity and coreceptor binding site exposure. J. Virol. 2004, 78, 4541-4551.
    • (2004) J. Virol. , vol.78 , pp. 4541-4551
    • Holm, G.H.1    Zhang, C.2    Gorry, P.R.3    Peden, K.4    Schols, D.5    de Clercq, E.6    Gabuzda, D.7
  • 81
    • 0032971372 scopus 로고    scopus 로고
    • Population biology of HIV-1 infection: Viral and CD4+ T cell demographics and dynamics in lymphatic tissues
    • Haase, A.T. Population biology of HIV-1 infection: viral and CD4+ T cell demographics and dynamics in lymphatic tissues. Annu. Rev. Immunol. 1999, 17, 625-656.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 625-656
    • Haase, A.T.1
  • 84
    • 17844374605 scopus 로고    scopus 로고
    • Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection
    • Mattapallil, J.J.; Douek, D.C.; Hill, B.; Nishimura, Y.; Martin, M.; Roederer, M. Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection. Nature 2005, 434, 1093-1097.
    • (2005) Nature , vol.434 , pp. 1093-1097
    • Mattapallil, J.J.1    Douek, D.C.2    Hill, B.3    Nishimura, Y.4    Martin, M.5    Roederer, M.6
  • 90
    • 0034715893 scopus 로고    scopus 로고
    • Apoptosis of syncytia induced by the HIV-1-envelope glycoprotein complex: Influence of cell shape and size
    • Ferri, K.F.; Jacotot, E.; Leduc, P.; Geuskens, M.; Ingber, D.E.; Kroemer, G. Apoptosis of syncytia induced by the HIV-1-envelope glycoprotein complex: influence of cell shape and size. Exp. Cell Res. 2000, 261, 119-126.
    • (2000) Exp. Cell Res. , vol.261 , pp. 119-126
    • Ferri, K.F.1    Jacotot, E.2    Leduc, P.3    Geuskens, M.4    Ingber, D.E.5    Kroemer, G.6
  • 93
    • 77955174045 scopus 로고    scopus 로고
    • Decreased CD4 and wide-ranging expression of other immune receptors after HIV-envelope-mediated formation of syncytia in vitro
    • Rivera-Toledo, E.; Lopez-Balderas, N.; Huerta, L.; Lamoyi, E.; Larralde, C. Decreased CD4 and wide-ranging expression of other immune receptors after HIV-envelope-mediated formation of syncytia in vitro. Arch. Virol. 2010, 155, 1205-1216.
    • (2010) Arch. Virol. , vol.155 , pp. 1205-1216
    • Rivera-Toledo, E.1    Lopez-Balderas, N.2    Huerta, L.3    Lamoyi, E.4    Larralde, C.5
  • 94
    • 39849096860 scopus 로고    scopus 로고
    • Immune activation and AIDS pathogenesis
    • Sodora, D.L.; Silvestri, G. Immune activation and AIDS pathogenesis. Aids 2008, 22, 439-446.
    • (2008) Aids , vol.22 , pp. 439-446
    • Sodora, D.L.1    Silvestri, G.2
  • 95
    • 77649250683 scopus 로고    scopus 로고
    • HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells
    • Prendergast, A.; Prado, J.G.; Kang, Y.H.; Chen, F.; Riddell, L.A.; Luzzi, G.; Goulder, P.; Klenerman, P. HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells. Aids 2010, 24, 491-502.
    • (2010) Aids , vol.24 , pp. 491-502
    • Prendergast, A.1    Prado, J.G.2    Kang, Y.H.3    Chen, F.4    Riddell, L.A.5    Luzzi, G.6    Goulder, P.7    Klenerman, P.8
  • 97
    • 50149092873 scopus 로고    scopus 로고
    • IL-23 and Th17 cytokines in intestinal homeostasis
    • Maloy, K.J.; Kullberg, M.C. IL-23 and Th17 cytokines in intestinal homeostasis. Mucosal Immunol. 2008, 1, 339-349.
    • (2008) Mucosal Immunol , vol.1 , pp. 339-349
    • Maloy, K.J.1    Kullberg, M.C.2
  • 101
    • 70349273714 scopus 로고    scopus 로고
    • Disturbance of the gut-associated lymphoid tissue is associated with disease progression in chronic HIV infection
    • Hofer, U.; Speck, R.F. Disturbance of the gut-associated lymphoid tissue is associated with disease progression in chronic HIV infection. Semin. Immunopathol. 2009, 31, 257-266.
    • (2009) Semin. Immunopathol , vol.31 , pp. 257-266
    • Hofer, U.1    Speck, R.F.2
  • 102
    • 0034641898 scopus 로고    scopus 로고
    • CD95's deadly mission in the immune system
    • Krammer, P.H. CD95's deadly mission in the immune system. Nature 2000, 407, 789-795.
    • (2000) Nature , vol.407 , pp. 789-795
    • Krammer, P.H.1
  • 104
    • 63449095109 scopus 로고    scopus 로고
    • Reassessing the role of APOBEC3G in human immunodeficiency virus type 1 infection of quiescent CD4+ T-cells
    • Kamata, M.; Nagaoka, Y.; Chen, I.S. Reassessing the role of APOBEC3G in human immunodeficiency virus type 1 infection of quiescent CD4+ T-cells. PLoS Pathog. 2009, 5, e1000342.
    • (2009) PLoS Pathog , vol.5
    • Kamata, M.1    Nagaoka, Y.2    Chen, I.S.3
  • 105
    • 13444309162 scopus 로고    scopus 로고
    • Kinetics of human immunodeficiency virus type 1 decay following entry into resting CD4+ T cells
    • Zhou, Y.; Zhang, H.; Siliciano, J.D.; Siliciano, R.F. Kinetics of human immunodeficiency virus type 1 decay following entry into resting CD4+ T cells. J. Virol. 2005, 79, 2199-2210.
    • (2005) J. Virol. , vol.79 , pp. 2199-2210
    • Zhou, Y.1    Zhang, H.2    Siliciano, J.D.3    Siliciano, R.F.4
  • 106
    • 18744378270 scopus 로고    scopus 로고
    • Death ligand-mediated apoptosis in HIV infection
    • Miura, Y.; Koyanagi, Y. Death ligand-mediated apoptosis in HIV infection. Rev. Med. Virol. 2005, 15, 169-178.
    • (2005) Rev. Med. Virol. , vol.15 , pp. 169-178
    • Miura, Y.1    Koyanagi, Y.2
  • 108
    • 58149114621 scopus 로고    scopus 로고
    • HAART reduces death ligand but not death receptors in lymphoid tissue of HIV-infected patients and simian immunodeficiency virus-infected macaques
    • Herbeuval, J.P.; Nilsson, J.; Boasso, A.; Hardy, A.W.; Vaccari, M.; Cecchinato, V.; Valeri, V.; Franchini, G.; Andersson, J.; Shearer, G.M. HAART reduces death ligand but not death receptors in lymphoid tissue of HIV-infected patients and simian immunodeficiency virus-infected macaques. Aids 2009, 23, 35-40.
    • (2009) Aids , vol.23 , pp. 35-40
    • Herbeuval, J.P.1    Nilsson, J.2    Boasso, A.3    Hardy, A.W.4    Vaccari, M.5    Cecchinato, V.6    Valeri, V.7    Franchini, G.8    Andersson, J.9    Shearer, G.M.10
  • 109
    • 0032563871 scopus 로고    scopus 로고
    • Fungal metabolite FR901228 inhibits c-Myc and Fas ligand expression
    • Wang, R.; Brunner, T.; Zhang, L.; Shi, Y. Fungal metabolite FR901228 inhibits c-Myc and Fas ligand expression. Oncogene 1998, 17, 1503-1508.
    • (1998) Oncogene , vol.17 , pp. 1503-1508
    • Wang, R.1    Brunner, T.2    Zhang, L.3    Shi, Y.4
  • 110
    • 0031563740 scopus 로고    scopus 로고
    • Activation-induced T cell death: Resistance or susceptibility correlate with cell surface fas ligand expression and T helper phenotype
    • Oberg, H.H.; Lengl-Janssen, B.; Kabelitz, D.; Janssen, O. Activation-induced T cell death: resistance or susceptibility correlate with cell surface fas ligand expression and T helper phenotype. Cell. Immunol. 1997, 181, 93-100.
    • (1997) Cell. Immunol. , vol.181 , pp. 93-100
    • Oberg, H.H.1    Lengl-Janssen, B.2    Kabelitz, D.3    Janssen, O.4
  • 111
    • 2642593019 scopus 로고    scopus 로고
    • Differential susceptibility to activation-induced apoptosis among peripheral Th1 subsets: Correlation with Bcl-2 expression and consequences for AIDS pathogenesis
    • Ledru, E.; Lecoeur, H.; Garcia, S.; Debord, T.; Gougeon, M.L. Differential susceptibility to activation-induced apoptosis among peripheral Th1 subsets: correlation with Bcl-2 expression and consequences for AIDS pathogenesis. J. Immunol. 1998, 160, 3194-3206.
    • (1998) J. Immunol. , vol.160 , pp. 3194-3206
    • Ledru, E.1    Lecoeur, H.2    Garcia, S.3    Debord, T.4    Gougeon, M.L.5
  • 112
    • 0038702580 scopus 로고    scopus 로고
    • Reciprocal expression of TRAIL and CD95L in Th1 and Th2 cells: Role of apoptosis in T helper subset differentiation
    • Zhang, X.R.; Zhang, L.Y.; Devadas, S.; Li, L.; Keegan, A.D.; Shi, Y.F. Reciprocal expression of TRAIL and CD95L in Th1 and Th2 cells: role of apoptosis in T helper subset differentiation. Cell Death Differ. 2003, 10, 203-210.
    • (2003) Cell Death Differ , vol.10 , pp. 203-210
    • Zhang, X.R.1    Zhang, L.Y.2    Devadas, S.3    Li, L.4    Keegan, A.D.5    Shi, Y.F.6
  • 114
  • 115
    • 34548764423 scopus 로고    scopus 로고
    • Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses
    • Denning, T.L.; Wang, Y.C.; Patel, S.R.; Williams, I.R.; Pulendran, B. Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses. Nat. Immunol. 2007, 8, 1086-1094.
    • (2007) Nat. Immunol. , vol.8 , pp. 1086-1094
    • Denning, T.L.1    Wang, Y.C.2    Patel, S.R.3    Williams, I.R.4    Pulendran, B.5
  • 117
    • 33847237223 scopus 로고    scopus 로고
    • The dynamic co-evolution of memory and regulatory CD4+ T cells in the periphery
    • Akbar, A.N.; Vukmanovic-Stejic, M.; Taams, L.S.; Macallan, D.C. The dynamic co-evolution of memory and regulatory CD4+ T cells in the periphery. Nat. Rev. Immunol. 2007, 7, 231-237.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 231-237
    • Akbar, A.N.1    Vukmanovic-Stejic, M.2    Taams, L.S.3    Macallan, D.C.4
  • 118
    • 1642577126 scopus 로고    scopus 로고
    • TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice
    • Nakamura, K.; Kitani, A.; Fuss, I.; Pedersen, A.; Harada, N.; Nawata, H.; Strober, W. TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice. J. Immunol. 2004, 172, 834-842.
    • (2004) J. Immunol. , vol.172 , pp. 834-842
    • Nakamura, K.1    Kitani, A.2    Fuss, I.3    Pedersen, A.4    Harada, N.5    Nawata, H.6    Strober, W.7
  • 119
    • 5644238762 scopus 로고    scopus 로고
    • Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells
    • Grossman, W.J.; Verbsky, J.W.; Tollefsen, B.L.; Kemper, C.; Atkinson, J.P.; Ley, T.J. Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells. Blood 2004, 104, 2840-2848.
    • (2004) Blood , vol.104 , pp. 2840-2848
    • Grossman, W.J.1    Verbsky, J.W.2    Tollefsen, B.L.3    Kemper, C.4    Atkinson, J.P.5    Ley, T.J.6
  • 121
    • 70349658485 scopus 로고    scopus 로고
    • Human regulatory T cell suppressive function is independent of apoptosis induction in activated effector T cells
    • Vercoulen, Y.; Wehrens, E.J.; van Teijlingen, N.H.; de Jager, W.; Beekman, J.M.; Prakken, B.J. Human regulatory T cell suppressive function is independent of apoptosis induction in activated effector T cells. PLoS ONE 2009, 4, e7183.
    • (2009) PLoS ONE , vol.4
    • Vercoulen, Y.1    Wehrens, E.J.2    van Teijlingen, N.H.3    de Jager, W.4    Beekman, J.M.5    Prakken, B.J.6
  • 122
    • 68249136806 scopus 로고    scopus 로고
    • The decrease of regulatory T cells correlates with excessive activation and apoptosis of CD8+ T cells in HIV-1-infected typical progressors, but not in long-term non-progressors
    • Jiao, Y.; Fu, J.; Xing, S.; Fu, B.; Zhang, Z.; Shi, M.; Wang, X.; Zhang, J.; Jin, L.; Kang, F.; Wu, H.; Wang, F.S. The decrease of regulatory T cells correlates with excessive activation and apoptosis of CD8+ T cells in HIV-1-infected typical progressors, but not in long-term non-progressors. Immunology 2009, 128, e366-375.
    • (2009) Immunology , vol.128
    • Jiao, Y.1    Fu, J.2    Xing, S.3    Fu, B.4    Zhang, Z.5    Shi, M.6    Wang, X.7    Zhang, J.8    Jin, L.9    Kang, F.10    Wu, H.11    Wang, F.S.12
  • 123
    • 61349156886 scopus 로고    scopus 로고
    • HIV-1 binding to CD4 on CD4+CD25+ regulatory T cells enhances their suppressive function and induces them to home to, and accumulate in, peripheral and mucosal lymphoid tissues: An additional mechanism of immunosuppression
    • Ji, J.; Cloyd, M.W. HIV-1 binding to CD4 on CD4+CD25+ regulatory T cells enhances their suppressive function and induces them to home to, and accumulate in, peripheral and mucosal lymphoid tissues: an additional mechanism of immunosuppression. Int. Immunol. 2009, 21, 283-294.
    • (2009) Int. Immunol. , vol.21 , pp. 283-294
    • Ji, J.1    Cloyd, M.W.2
  • 124
    • 40449092356 scopus 로고    scopus 로고
    • Naive precursors of human regulatory T cells require FoxP3 for suppression and are susceptible to HIV infection
    • Antons, A.K.; Wang, R.; Oswald-Richter, K.; Tseng, M.; Arendt, C.W.; Kalams, S.A.; Unutmaz, D. Naive precursors of human regulatory T cells require FoxP3 for suppression and are susceptible to HIV infection. J. Immunol. 2008, 180, 764-773.
    • (2008) J. Immunol. , vol.180 , pp. 764-773
    • Antons, A.K.1    Wang, R.2    Oswald-Richter, K.3    Tseng, M.4    Arendt, C.W.5    Kalams, S.A.6    Unutmaz, D.7
  • 125
    • 77955013981 scopus 로고    scopus 로고
    • Increased turnover of FoxP3high regulatory T cells is associated with hyperactivation and disease progression of chronic HIV-1 infection
    • Xing, S.; Fu, J.; Zhang, Z.; Gao, Y.; Jiao, Y.; Kang, F.; Zhang, J.; Zhou, C.; Wu, H.; Wang, F.S. Increased turnover of FoxP3high regulatory T cells is associated with hyperactivation and disease progression of chronic HIV-1 infection. J. Acquir. Immune Defic. Syndr. 2010, 54, 455-462.
    • (2010) J. Acquir. Immune Defic. Syndr. , vol.54 , pp. 455-462
    • Xing, S.1    Fu, J.2    Zhang, Z.3    Gao, Y.4    Jiao, Y.5    Kang, F.6    Zhang, J.7    Zhou, C.8    Wu, H.9    Wang, F.S.10
  • 126
    • 21244465055 scopus 로고    scopus 로고
    • In contrast to effector T cells, CD4+CD25+FoxP3+ regulatory T cells are highly susceptible to CD95 ligand- but not to TCR-mediated cell death
    • Fritzsching, B.; Oberle, N.; Eberhardt, N.; Quick, S.; Haas, J.; Wildemann, B.; Krammer, P. H.; Suri-Payer, E. In contrast to effector T cells, CD4+CD25+FoxP3+ regulatory T cells are highly susceptible to CD95 ligand- but not to TCR-mediated cell death. J. Immunol. 2005, 175, 32-36.
    • (2005) J. Immunol. , vol.175 , pp. 32-36
    • Fritzsching, B.1    Oberle, N.2    Eberhardt, N.3    Quick, S.4    Haas, J.5    Wildemann, B.6    Krammer, P.H.7    Suri-Payer, E.8
  • 128
    • 50149097478 scopus 로고    scopus 로고
    • Preservation of FoxP3+ regulatory T cells in the peripheral blood of human immunodeficiency virus type 1-infected elite suppressors correlates with low CD4+ T-cell activation
    • Chase, A.J.; Yang, H.C.; Zhang, H.; Blankson, J.N.; Siliciano, R.F. Preservation of FoxP3+ regulatory T cells in the peripheral blood of human immunodeficiency virus type 1-infected elite suppressors correlates with low CD4+ T-cell activation. J. Virol. 2008, 82, 8307-8315.
    • (2008) J. Virol. , vol.82 , pp. 8307-8315
    • Chase, A.J.1    Yang, H.C.2    Zhang, H.3    Blankson, J.N.4    Siliciano, R.F.5
  • 130
  • 131
    • 41349101159 scopus 로고    scopus 로고
    • Regulatory T cells in HIV infection: Pathogenic or protective participants in the immune response?
    • Fazekas de St Groth, B.; Landay, A.L. Regulatory T cells in HIV infection: pathogenic or protective participants in the immune response? Aids 2008, 22, 671-683.
    • (2008) Aids , vol.22 , pp. 671-683
    • Fazekas de St Groth, B.1    Landay, A.L.2
  • 132
    • 78650623074 scopus 로고    scopus 로고
    • SIV infection in natural hosts: Resolution of immune activation during the acute-to-chronic transition phase
    • Mir, K.D.; Gasper, M.A.; Sundaravaradan, V.; Sodora, D.L. SIV infection in natural hosts: resolution of immune activation during the acute-to-chronic transition phase. Microbes. Infect. 2011, 13, 14-24.
    • (2011) Microbes. Infect. , vol.13 , pp. 14-24
    • Mir, K.D.1    Gasper, M.A.2    Sundaravaradan, V.3    Sodora, D.L.4
  • 133
    • 39749189476 scopus 로고    scopus 로고
    • Apoptosis and HIV infection: About molecules and genes
    • Cossarizza, A. Apoptosis and HIV infection: about molecules and genes. Curr. Pharm. Des. 2008, 14, 237-244.
    • (2008) Curr. Pharm. Des. , vol.14 , pp. 237-244
    • Cossarizza, A.1
  • 135
  • 136
    • 0034899305 scopus 로고    scopus 로고
    • Binding of human immunodeficiency virus type 1 gp120 to CXCR4 induces mitochondrial transmembrane depolarization and cytochrome c-mediated apoptosis independently of Fas signaling
    • Roggero, R.; Robert-Hebmann, V.; Harrington, S.; Roland, J.; Vergne, L.; Jaleco, S.; Devaux, C.; Biard-Piechaczyk, M. Binding of human immunodeficiency virus type 1 gp120 to CXCR4 induces mitochondrial transmembrane depolarization and cytochrome c-mediated apoptosis independently of Fas signaling. J. Virol. 2001, 75, 7637-7650.
    • (2001) J. Virol. , vol.75 , pp. 7637-7650
    • Roggero, R.1    Robert-Hebmann, V.2    Harrington, S.3    Roland, J.4    Vergne, L.5    Jaleco, S.6    Devaux, C.7    Biard-Piechaczyk, M.8
  • 140
    • 0032959989 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Nef protein sensitizes CD4(+) T lymphoid cells to apoptosis via functional upregulation of the CD95/CD95 ligand pathway
    • Zauli, G.; Gibellini, D.; Secchiero, P.; Dutartre, H.; Olive, D.; Capitani, S.; Collette, Y. Human immunodeficiency virus type 1 Nef protein sensitizes CD4(+) T lymphoid cells to apoptosis via functional upregulation of the CD95/CD95 ligand pathway. Blood 1999, 93, 1000-1010.
    • (1999) Blood , vol.93 , pp. 1000-1010
    • Zauli, G.1    Gibellini, D.2    Secchiero, P.3    Dutartre, H.4    Olive, D.5    Capitani, S.6    Collette, Y.7
  • 142
    • 1542317632 scopus 로고    scopus 로고
    • Extracellular Nef protein targets CD4+ T cells for apoptosis by interacting with CXCR4 surface receptors
    • James, C.O.; Huang, M.B.; Khan, M.; Garcia-Barrio, M.; Powell, M.D.; Bond, V.C. Extracellular Nef protein targets CD4+ T cells for apoptosis by interacting with CXCR4 surface receptors. J. Virol. 2004, 78, 3099-3109.
    • (2004) J. Virol. , vol.78 , pp. 3099-3109
    • James, C.O.1    Huang, M.B.2    Khan, M.3    Garcia-Barrio, M.4    Powell, M.D.5    Bond, V.C.6
  • 143
    • 79951687153 scopus 로고    scopus 로고
    • HIV Type 1 Nef Is Released from Infected Cells in CD45(+) Microvesicles and Is Present in the Plasma of HIV-Infected Individuals
    • Raymond, A.D.; Campbell-Sims, T.C.; Khan, M.; Lang, M.; Huang, M.B.; Bond, V.C.; Powell, M.D. HIV Type 1 Nef Is Released from Infected Cells in CD45(+) Microvesicles and Is Present in the Plasma of HIV-Infected Individuals. AIDS Res. Hum. Retroviruses 2011, 27, 167-178.
    • (2011) AIDS Res. Hum. Retroviruses , vol.27 , pp. 167-178
    • Raymond, A.D.1    Campbell-Sims, T.C.2    Khan, M.3    Lang, M.4    Huang, M.B.5    Bond, V.C.6    Powell, M.D.7
  • 146
    • 0024262589 scopus 로고
    • Cellular uptake of the tat protein from human immunodeficiency virus
    • Frankel, A.D.; Pabo, C.O. Cellular uptake of the tat protein from human immunodeficiency virus. Cell 1988, 55, 1189-1193.
    • (1988) Cell , vol.55 , pp. 1189-1193
    • Frankel, A.D.1    Pabo, C.O.2
  • 147
    • 77950521612 scopus 로고    scopus 로고
    • Enhancement of TAT cell membrane penetration efficiency by dimethyl sulphoxide
    • Wang, H.; Zhong, C.Y.; Wu, J.F.; Huang, Y.B.; Liu, C.B. Enhancement of TAT cell membrane penetration efficiency by dimethyl sulphoxide. J. Control. Release 2010, 143, 64-70.
    • (2010) J. Control. Release , vol.143 , pp. 64-70
    • Wang, H.1    Zhong, C.Y.2    Wu, J.F.3    Huang, Y.B.4    Liu, C.B.5
  • 148
    • 0038725688 scopus 로고    scopus 로고
    • Apoptosis as an HIV strategy to escape immune attack
    • Gougeon, M.L. Apoptosis as an HIV strategy to escape immune attack. Nat. Rev. Immunol. 2003, 3, 392-404.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 392-404
    • Gougeon, M.L.1
  • 150
    • 0029062573 scopus 로고
    • Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein
    • Li, C.J.; Friedman, D.J.; Wang, C.; Metelev, V.; Pardee, A.B. Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein. Science 1995, 268, 429-431.
    • (1995) Science , vol.268 , pp. 429-431
    • Li, C.J.1    Friedman, D.J.2    Wang, C.3    Metelev, V.4    Pardee, A.B.5
  • 151
    • 58849121857 scopus 로고    scopus 로고
    • Tat-induced FOXO3a is a key mediator of apoptosis in HIV-1-infected human CD4+ T lymphocytes
    • Dabrowska, A.; Kim, N.; Aldovini, A. Tat-induced FOXO3a is a key mediator of apoptosis in HIV-1-infected human CD4+ T lymphocytes. J. Immunol. 2008, 181, 8460-8477.
    • (2008) J. Immunol. , vol.181 , pp. 8460-8477
    • Dabrowska, A.1    Kim, N.2    Aldovini, A.3
  • 152
    • 78149295173 scopus 로고    scopus 로고
    • Association of Tat with promoters of PTEN and PP2A subunits is key to transcriptional activation of apoptotic pathways in HIV-infected CD4+ T cells
    • Kim, N.; Kukkonen, S.; Gupta, S.; Aldovini, A. Association of Tat with promoters of PTEN and PP2A subunits is key to transcriptional activation of apoptotic pathways in HIV-infected CD4+ T cells. PLoS Pathog. 2010, 6, e1001103.
    • (2010) PLoS Pathog , vol.6
    • Kim, N.1    Kukkonen, S.2    Gupta, S.3    Aldovini, A.4
  • 153
    • 76149115904 scopus 로고    scopus 로고
    • HIV-1 Tat regulates cyclin B1 by promoting both expression and degradation
    • Zhang, S.M.; Sun, Y.; Fan, R.; Xu, Q.Z.; Liu, X.D.; Zhang, X.; Wang, Y.; Zhou, P.K. HIV-1 Tat regulates cyclin B1 by promoting both expression and degradation. FASEB J. 2010, 24, 495-503.
    • (2010) FASEB J , vol.24 , pp. 495-503
    • Zhang, S.M.1    Sun, Y.2    Fan, R.3    Xu, Q.Z.4    Liu, X.D.5    Zhang, X.6    Wang, Y.7    Zhou, P.K.8
  • 154
    • 0039129153 scopus 로고    scopus 로고
    • Expression of human immunodeficiency virus type I tat results in down-regulation of bcl-2 and induction of apoptosis in hematopoietic cells
    • Sastry, K.J.; Marin, M.C.; Nehete, P.N.; McConnell, K.; el-Naggar, A.K.; McDonnell, T.J. Expression of human immunodeficiency virus type I tat results in down-regulation of bcl-2 and induction of apoptosis in hematopoietic cells. Oncogene 1996, 13, 487-493.
    • (1996) Oncogene , vol.13 , pp. 487-493
    • Sastry, K.J.1    Marin, M.C.2    Nehete, P.N.3    McConnell, K.4    El-Naggar, A.K.5    McDonnell, T.J.6
  • 155
    • 0032978963 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Tat induces apoptosis and increases sensitivity to apoptotic signals by up-regulating FLICE/caspase-8
    • Bartz, S.R.; Emerman, M. Human immunodeficiency virus type 1 Tat induces apoptosis and increases sensitivity to apoptotic signals by up-regulating FLICE/caspase-8. J. Virol. 1999, 73, 1956-1963.
    • (1999) J. Virol. , vol.73 , pp. 1956-1963
    • Bartz, S.R.1    Emerman, M.2
  • 158
    • 64749109558 scopus 로고    scopus 로고
    • Structure-function relationship of Vpr: Biological implications
    • Morellet, N.; Roques, B.P.; Bouaziz, S. Structure-function relationship of Vpr: Biological implications. Curr. HIV Res. 2009, 7, 184-210.
    • (2009) Curr. HIV Res. , vol.7 , pp. 184-210
    • Morellet, N.1    Roques, B.P.2    Bouaziz, S.3
  • 159
    • 0037020155 scopus 로고    scopus 로고
    • HIV-1 Vpr induces apoptosis through caspase 9 in T cells and peripheral blood mononuclear cells
    • Muthumani, K.; Hwang, D.S.; Desai, B.M.; Zhang, D.; Dayes, N.; Green, D.R.; Weiner, D.B. HIV-1 Vpr induces apoptosis through caspase 9 in T cells and peripheral blood mononuclear cells. J. Biol. Chem. 2002, 277, 37820-37831.
    • (2002) J. Biol. Chem. , vol.277 , pp. 37820-37831
    • Muthumani, K.1    Hwang, D.S.2    Desai, B.M.3    Zhang, D.4    Dayes, N.5    Green, D.R.6    Weiner, D.B.7
  • 161
    • 70350291528 scopus 로고    scopus 로고
    • Virion-associated Vpr of human immunodeficiency virus type 1 triggers activation of apoptotic events and enhances fas-induced apoptosis in human T cells
    • Arokium, H.; Kamata, M.; Chen, I. Virion-associated Vpr of human immunodeficiency virus type 1 triggers activation of apoptotic events and enhances fas-induced apoptosis in human T cells. J. Virol. 2009, 83, 11283-11297.
    • (2009) J. Virol. , vol.83 , pp. 11283-11297
    • Arokium, H.1    Kamata, M.2    Chen, I.3
  • 163
    • 33646052566 scopus 로고    scopus 로고
    • Immunological recovery and antiretroviral therapy in HIV-1 infection
    • Battegay, M.; Nuesch, R.; Hirschel, B.; Kaufmann, G.R. Immunological recovery and antiretroviral therapy in HIV-1 infection. Lancet Infect. Dis. 2006, 6, 280-287.
    • (2006) Lancet Infect. Dis. , vol.6 , pp. 280-287
    • Battegay, M.1    Nuesch, R.2    Hirschel, B.3    Kaufmann, G.R.4
  • 165
  • 166
    • 79955467398 scopus 로고    scopus 로고
    • Epidemiology and clinical characteristics of elite controllers
    • Okulicz, J.F.; Lambotte, O. Epidemiology and clinical characteristics of elite controllers. Curr. Opin. HIV AIDS 2011, 6, 163-168.
    • (2011) Curr. Opin. HIV AIDS , vol.6 , pp. 163-168
    • Okulicz, J.F.1    Lambotte, O.2
  • 168
    • 79957940672 scopus 로고    scopus 로고
    • Low level of regulatory T-cells and maintenance of balance between regulatory T-cells and TH17 cells in HIV-1-infected Elite Controllers
    • doi:10.1097/QAI.0b013e318215a991
    • Brandt, L.; Benfield, T.; Mens, H.; Clausen, L.N.; Katzenstein, T.L.; Fomsgaard, A.; Karlsson, I. Low level of regulatory T-cells and maintenance of balance between regulatory T-cells and TH17 cells in HIV-1-infected Elite Controllers. J. Acquir. Immune Defic. Syndr. 2011, doi:10.1097/QAI.0b013e318215a991.
    • (2011) J. Acquir. Immune Defic. Syndr.
    • Brandt, L.1    Benfield, T.2    Mens, H.3    Clausen, L.N.4    Katzenstein, T.L.5    Fomsgaard, A.6    Karlsson, I.7
  • 170
    • 78650657805 scopus 로고    scopus 로고
    • Unstimulated primary CD4+ T cells from HIV-1-positive elite suppressors are fully susceptible to HIV-1 entry and productive infection
    • Rabi, S.A.; O'Connell, K.A.; Nikolaeva, D.; Bailey, J.R.; Jilek, B.L.; Shen, L.; Page, K.R.; Siliciano, R.F.; Blankson, J.N. Unstimulated primary CD4+ T cells from HIV-1-positive elite suppressors are fully susceptible to HIV-1 entry and productive infection. J. Virol. 2011, 85, 979-986.
    • (2011) J. Virol. , vol.85 , pp. 979-986
    • Rabi, S.A.1    O'Connell, K.A.2    Nikolaeva, D.3    Bailey, J.R.4    Jilek, B.L.5    Shen, L.6    Page, K.R.7    Siliciano, R.F.8    Blankson, J.N.9
  • 171
    • 79951707505 scopus 로고    scopus 로고
    • Elite controllers display higher activation on central memory CD8 T cells than HIV patients successfully on HAART
    • Lopez, M.; Soriano, V.; Peris-Pertusa, A.; Rallon, N.; Restrepo, C.; Benito, J.M. Elite controllers display higher activation on central memory CD8 T cells than HIV patients successfully on HAART. AIDS Res. Hum. Retroviruses 2011, 27, 157-165.
    • (2011) AIDS Res. Hum. Retroviruses , vol.27 , pp. 157-165
    • Lopez, M.1    Soriano, V.2    Peris-Pertusa, A.3    Rallon, N.4    Restrepo, C.5    Benito, J.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.