메뉴 건너뛰기




Volumn 25, Issue 6, 2011, Pages 741-749

Sigmoid Th17 populations, the HIV latent reservoir, and microbial translocation in men on long-term antiretroviral therapy

Author keywords

antiretroviral therapy; microbial translocation; provirus; sigmoid colon; Th17 cells

Indexed keywords

CD4 ANTIGEN; LIPOPOLYSACCHARIDE; VIRUS DNA;

EID: 79953735335     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e328344cefb     Document Type: Article
Times cited : (123)

References (38)
  • 1
    • 33645924682 scopus 로고    scopus 로고
    • HIV disease: Fallout from a mucosal catastrophe?
    • Brenchley JM, Price DA, Douek DC. HIV disease: fallout from a mucosal catastrophe? Nat Immunol 2006; 7:235-239.
    • (2006) Nat Immunol , vol.7 , pp. 235-239
    • Brenchley, J.M.1    Price, D.A.2    Douek, D.C.3
  • 2
    • 0020596551 scopus 로고
    • Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS)
    • Barre-Sinoussi F, Chermann JC, Rey F, Nugeyre MT, Chamaret S, Gruest J, et al. Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). Science 1983; 220:868-871.
    • (1983) Science , vol.220 , pp. 868-871
    • Barre-Sinoussi, F.1    Chermann, J.C.2    Rey, F.3    Nugeyre, M.T.4    Chamaret, S.5    Gruest, J.6
  • 5
    • 33749318470 scopus 로고    scopus 로고
    • Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
    • Liang SC, Tan XY, Luxenberg DP, Karim R, Dunussi-Joannopoulos K, Collins M, et al. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med 2006;203:2271-2279.
    • (2006) J Exp Med , vol.203 , pp. 2271-2279
    • Liang, S.C.1    Tan, X.Y.2    Luxenberg, D.P.3    Karim, R.4    Dunussi-Joannopoulos, K.5    Collins, M.6
  • 6
    • 41549135632 scopus 로고    scopus 로고
    • The biological functions of T helper 17 cell effector cytokines in inflammation
    • Ouyang W, Kolls JK, Zheng Y. The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity 2008; 28:454-467.
    • (2008) Immunity , vol.28 , pp. 454-467
    • Ouyang, W.1    Kolls, J.K.2    Zheng, Y.3
  • 7
    • 77149147477 scopus 로고    scopus 로고
    • Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines
    • Kisand K, Boe Wolff AS, Podkrajsek KT, Tserel L, Link M, Kisand KV, et al. Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines. J Exp Med 2010.
    • (2010) J Exp Med
    • Kisand, K.1    Boe Wolff, A.S.2    Podkrajsek, K.T.3    Tserel, L.4    Link, M.5    Kisand, K.V.6
  • 8
    • 77954738601 scopus 로고    scopus 로고
    • Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota
    • Round JL, Mazmanian SK. Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota. Proc Natl Acad Sci U S A 2010; 107:12204-12209.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 12204-12209
    • Round, J.L.1    Mazmanian, S.K.2
  • 10
    • 53349173070 scopus 로고    scopus 로고
    • Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine
    • Ivanov II, Frutos Rde L, Manel N, Yoshinaga K, Rifkin DB, Sartor RB, et al. Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine. Cell Host Microbe 2008; 4:337-349.
    • (2008) Cell Host Microbe , vol.4 , pp. 337-349
    • Ivanov, I.I.1    Frutos, Rde.L.2    Manel, N.3    Yoshinaga, K.4    Rifkin, D.B.5    Sartor, R.B.6
  • 11
    • 76949108202 scopus 로고    scopus 로고
    • Th17 and regulatory T cells: Implications for AIDS pathogenesis
    • Kanwar B, Favre D, McCune JM. Th17 and regulatory T cells: implications for AIDS pathogenesis. Curr Opin HIV AIDS 2010;5:151-157.
    • (2010) Curr Opin HIV AIDS , vol.5 , pp. 151-157
    • Kanwar, B.1    Favre, D.2    McCune, J.M.3
  • 12
    • 69249153068 scopus 로고    scopus 로고
    • Alpha4(+)beta7(hi)CD4(+) memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection
    • Kader M, Wang X, Piatak M, Lifson J, Roederer M, Veazey R, et al. Alpha4(+)beta7(hi)CD4(+) memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection. Mucosal Immunol 2009; 2:439-449.
    • (2009) Mucosal Immunol , vol.2 , pp. 439-449
    • Kader, M.1    Wang, X.2    Piatak, M.3    Lifson, J.4    Roederer, M.5    Veazey, R.6
  • 13
    • 45449104669 scopus 로고    scopus 로고
    • Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques
    • Cecchinato V, Trindade CJ, Laurence A, Heraud JM, Brenchley JM, Ferrari MG, et al. Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques. Mucosal Immunol 2008; 1:279-288.
    • (2008) Mucosal Immunol , vol.1 , pp. 279-288
    • Cecchinato, V.1    Trindade, C.J.2    Laurence, A.3    Heraud, J.M.4    Brenchley, J.M.5    Ferrari, M.G.6
  • 14
    • 53449093632 scopus 로고    scopus 로고
    • Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections
    • Brenchley JM, Paiardini M, Knox KS, Asher AI, Cervasi B, Asher TE, et al. Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 2008; 112:2826-2835.
    • (2008) Blood , vol.112 , pp. 2826-2835
    • Brenchley, J.M.1    Paiardini, M.2    Knox, K.S.3    Asher, A.I.4    Cervasi, B.5    Asher, T.E.6
  • 15
    • 77952977625 scopus 로고    scopus 로고
    • Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease
    • Favre D, Mold J, Hunt PW, Kanwar B, Loke P, Seu L, et al. Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease. Sci Transl Med 2010; 2:32ra36.
    • (2010) Sci Transl Med , vol.2
    • Favre, D.1    Mold, J.2    Hunt, P.W.3    Kanwar, B.4    Loke, P.5    Seu, L.6
  • 16
    • 61449115882 scopus 로고    scopus 로고
    • Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection
    • Favre D, Lederer S, Kanwar B, Ma ZM, Proll S, Kasakow Z, et al. Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection. PLoS Pathog 2009;5:e1000295.
    • (2009) PLoS Pathog , vol.5
    • Favre, D.1    Lederer, S.2    Kanwar, B.3    Ma, Z.M.4    Proll, S.5    Kasakow, Z.6
  • 17
    • 76949090546 scopus 로고    scopus 로고
    • Th17 cells in pathogenic simian immunodeficiency virus infection of macaques
    • Cecchinato V, Franchini G. Th17 cells in pathogenic simian immunodeficiency virus infection of macaques. Curr Opin HIV AIDS 2010; 5:141-145.
    • (2010) Curr Opin HIV AIDS , vol.5 , pp. 141-145
    • Cecchinato, V.1    Franchini, G.2
  • 18
    • 0142092389 scopus 로고    scopus 로고
    • Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy
    • Guadalupe M, Reay E, Sankaran S, Prindiville T, Flamm J, McNeil A, et al. Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy. J Virol 2003; 77:11708-11717.
    • (2003) J Virol , vol.77 , pp. 11708-11717
    • Guadalupe, M.1    Reay, E.2    Sankaran, S.3    Prindiville, T.4    Flamm, J.5    McNeil, A.6
  • 20
    • 40549092339 scopus 로고    scopus 로고
    • Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy
    • Chun TW, Nickle DC, Justement JS, Meyers JH, Roby G, Hallahan CW, et al. Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy. J Infect Dis 2008; 197:714-720.
    • (2008) J Infect Dis , vol.197 , pp. 714-720
    • Chun, T.W.1    Nickle, D.C.2    Justement, J.S.3    Meyers, J.H.4    Roby, G.5    Hallahan, C.W.6
  • 21
    • 75349114036 scopus 로고    scopus 로고
    • Immune dysfunction, inflammation, and accelerated aging in patients on antiretroviral therapy
    • Deeks SG. Immune dysfunction, inflammation, and accelerated aging in patients on antiretroviral therapy. Top HIV Med 2009; 17:118-123.
    • (2009) Top HIV Med , vol.17 , pp. 118-123
    • Deeks, S.G.1
  • 22
    • 65649102237 scopus 로고    scopus 로고
    • Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection
    • Jiang W, Lederman MM, Hunt P, Sieg SF, Haley K, Rodriguez B, et al. Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection. J Infect Dis 2009;199:1177-1185.
    • (2009) J Infect Dis , vol.199 , pp. 1177-1185
    • Jiang, W.1    Lederman, M.M.2    Hunt, P.3    Sieg, S.F.4    Haley, K.5    Rodriguez, B.6
  • 23
    • 70049083457 scopus 로고    scopus 로고
    • Cardiovascular disease in adult and pediatric HIV/AIDS
    • McDonald CL, Kaltman JR. Cardiovascular disease in adult and pediatric HIV/AIDS. J Am Coll Cardiol 2009; 54:1185-1188.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 1185-1188
    • McDonald, C.L.1    Kaltman, J.R.2
  • 24
    • 48949097660 scopus 로고    scopus 로고
    • Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society - USA panel
    • Hammer SM, Eron JJ Jr, Reiss P, Schooley RT, Thompson MA, Walmsley S, et al. Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society - USA panel. JAMA 2008; 300:555-570.
    • (2008) JAMA , vol.300 , pp. 555-570
    • Hammer, S.M.1    Eron Jr., J.J.2    Reiss, P.3    Schooley, R.T.4    Thompson, M.A.5    Walmsley, S.6
  • 25
    • 25444498269 scopus 로고    scopus 로고
    • HIV-specific CD8+ lymphocytes in semen are not associated with reduced HIV shedding
    • Sheth PM, Danesh A, Shahabi K, Rebbapragada A, Kovacs C, Dimayuga R, et al. HIV-specific CD8+ lymphocytes in semen are not associated with reduced HIV shedding. J Immunol 2005; 175:4789-4796.
    • (2005) J Immunol , vol.175 , pp. 4789-4796
    • Sheth, P.M.1    Danesh, A.2    Shahabi, K.3    Rebbapragada, A.4    Kovacs, C.5    Dimayuga, R.6
  • 26
    • 33845532053 scopus 로고    scopus 로고
    • Microbial translocation is a cause of systemic immune activation in chronic HIV infection
    • Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat Med 2006;12:1365-1371.
    • (2006) Nat Med , vol.12 , pp. 1365-1371
    • Brenchley, J.M.1    Price, D.A.2    Schacker, T.W.3    Asher, T.E.4    Silvestri, G.5    Rao, S.6
  • 27
    • 9244220630 scopus 로고    scopus 로고
    • Insufficient production and tissue delivery of CD4+ memory T cells in rapidly progressive simian immunodeficiency virus infection
    • Picker LJ, Hagen SI, Lum R, Reed-Inderbitzin EF, Daly LM, Sylwester AW, et al. Insufficient production and tissue delivery of CD4+ memory T cells in rapidly progressive simian immunodeficiency virus infection. J Exp Med 2004; 200:1299-1314.
    • (2004) J Exp Med , vol.200 , pp. 1299-1314
    • Picker, L.J.1    Hagen, S.I.2    Lum, R.3    Reed-Inderbitzin, E.F.4    Daly, L.M.5    Sylwester, A.W.6
  • 28
    • 0027298094 scopus 로고
    • Intestinal mucosal inflammation associated with human immunodeficiency virus infection
    • Kotler DP, Reka S, Clayton F. Intestinal mucosal inflammation associated with human immunodeficiency virus infection. Dig Dis Sci 1993; 38:1119-1127.
    • (1993) Dig Dis Sci , vol.38 , pp. 1119-1127
    • Kotler, D.P.1    Reka, S.2    Clayton, F.3
  • 29
    • 0026631292 scopus 로고
    • Enteric immunologic abnormalities in human immunodeficiency virus infection
    • Ullrich R, Zeitz M, Riecken EO. Enteric immunologic abnormalities in human immunodeficiency virus infection. Semin Liver Dis 1992; 12:167-174.
    • (1992) Semin Liver Dis , vol.12 , pp. 167-174
    • Ullrich, R.1    Zeitz, M.2    Riecken, E.O.3
  • 30
    • 66249085573 scopus 로고    scopus 로고
    • HIV-1 RNA dysregulates the natural TLR response to subclinical endotoxemia in Kenyan female sex-workers
    • Lester RT, Yao XD, Ball TB, McKinnon LR, Omange WR, Kaul R, et al. HIV-1 RNA dysregulates the natural TLR response to subclinical endotoxemia in Kenyan female sex-workers. PLoS One 2009; 4:e5644.
    • (2009) PLoS One , vol.4
    • Lester, R.T.1    Yao, X.D.2    Ball, T.B.3    McKinnon, L.R.4    Omange, W.R.5    Kaul, R.6
  • 31
    • 77952916199 scopus 로고    scopus 로고
    • Microbial translocation induces persistent macrophage activation unrelated to HIV-1 levels or T-cell activation following therapy
    • Wallet MA, Rodriguez CA, Yin L, Saporta S, Chinratanapisit S, Hou W, et al. Microbial translocation induces persistent macrophage activation unrelated to HIV-1 levels or T-cell activation following therapy. AIDS 2010; 24:1281-1290.
    • (2010) AIDS , vol.24 , pp. 1281-1290
    • Wallet, M.A.1    Rodriguez, C.A.2    Yin, L.3    Saporta, S.4    Chinratanapisit, S.5    Hou, W.6
  • 32
    • 77954059792 scopus 로고    scopus 로고
    • Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial translocation
    • Nazli A, Chan O, Dobson-Belaire WN, Ouellet M, Tremblay MJ, Gray-Owen SD, et al. Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial translocation. PLoS Pathog 2010; 6:e1000852.
    • (2010) PLoS Pathog , vol.6
    • Nazli, A.1    Chan, O.2    Dobson-Belaire, W.N.3    Ouellet, M.4    Tremblay, M.J.5    Gray-Owen, S.D.6
  • 33
    • 54449084622 scopus 로고    scopus 로고
    • Effective CD4+ T-cell restoration in gut-associated lymphoid tissue of HIV-infected patients is associated with enhanced Th17 cells and polyfunctional HIV-specific T-cell responses
    • Macal M, Sankaran S, Chun TW, Reay E, Flamm J, Prindiville TJ, et al. Effective CD4+ T-cell restoration in gut-associated lymphoid tissue of HIV-infected patients is associated with enhanced Th17 cells and polyfunctional HIV-specific T-cell responses. Mucosal Immunol 2008; 1:475.
    • (2008) Mucosal Immunol , vol.1 , pp. 475
    • Macal, M.1    Sankaran, S.2    Chun, T.W.3    Reay, E.4    Flamm, J.5    Prindiville, T.J.6
  • 34
    • 10744227590 scopus 로고    scopus 로고
    • Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalo-virus antigens
    • Aandahl EM, Michaelsson J, Moretto WJ, Hecht FM, Nixon DF. Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalo-virus antigens. J Virol 2004; 78:2454-2459.
    • (2004) J Virol , vol.78 , pp. 2454-2459
    • Aandahl, E.M.1    Michaelsson, J.2    Moretto, W.J.3    Hecht, F.M.4    Nixon, D.F.5
  • 35
    • 17444407451 scopus 로고    scopus 로고
    • The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients
    • Andersson J, Boasso A, Nilsson J, Zhang R, Shire NJ, Lindback S, et al. The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients. J Immunol 2005; 174:3143-3147.
    • (2005) J Immunol , vol.174 , pp. 3143-3147
    • Andersson, J.1    Boasso, A.2    Nilsson, J.3    Zhang, R.4    Shire, N.J.5    Lindback, S.6
  • 36
    • 53549129725 scopus 로고    scopus 로고
    • Microbial translocation is associated with sustained failure in CD4+ T-cell reconstitution in HIV-infected patients on long-term highly active antiretroviral therapy
    • Marchetti G, Bellistri GM, Borghi E, Tincati C, Ferramosca S, La Francesca M, et al. Microbial translocation is associated with sustained failure in CD4+ T-cell reconstitution in HIV-infected patients on long-term highly active antiretroviral therapy. AIDS 2008; 22:2035-2038.
    • (2008) AIDS , vol.22 , pp. 2035-2038
    • Marchetti, G.1    Bellistri, G.M.2    Borghi, E.3    Tincati, C.4    Ferramosca, S.5    La Francesca, M.6
  • 37
    • 77954349457 scopus 로고    scopus 로고
    • Elevated plasma levels of lipopolysaccharide and high mobility group box-1 protein are associated with high viral load in HIV-1 infection: Reduction by 2-year antiretroviral therapy
    • Troseid M, Nowak P, Nystrom J, Lindkvist A, Abdurahman S, Sonnerborg A. Elevated plasma levels of lipopolysaccharide and high mobility group box-1 protein are associated with high viral load in HIV-1 infection: reduction by 2-year antiretroviral therapy. AIDS 2010; 24:1733-1737.
    • (2010) AIDS , vol.24 , pp. 1733-1737
    • Troseid, M.1    Nowak, P.2    Nystrom, J.3    Lindkvist, A.4    Abdurahman, S.5    Sonnerborg, A.6
  • 38
    • 0032968238 scopus 로고    scopus 로고
    • Relationship of antibodies to endotoxin core to mortality in medical patients with sepsis syndrome
    • Strutz F, Heller G, Krasemann K, Krone B, Muller GA. Relationship of antibodies to endotoxin core to mortality in medical patients with sepsis syndrome. Intensive Care Med 1999; 25:435-444.
    • (1999) Intensive Care Med , vol.25 , pp. 435-444
    • Strutz, F.1    Heller, G.2    Krasemann, K.3    Krone, B.4    Muller, G.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.