HIV: Current opinion in escapology

Current Opinion in Microbiology

Volumn 5, Issue 4, 2002, Pages 408-413

  Klenerman, Paul ^a   Wu, Ying ^a   Phillips, Rodney ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENICITY; CYTOTOXIC T LYMPHOCYTE; GENE MUTATION; HOST PATHOGEN INTERACTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNITY; NONHUMAN; REVIEW; VIRUS GENE; VIRUS RESISTANCE;

EID: 0036342926     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1369-5274(02)00339-9     Document Type: Review

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10. + T cells
11. Persistence of HIV-1 specific CTL clones in a subject with rapid progression
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13. Impaired function of circulating HIV-specific CD8(+) T cells in chronic HIV infection
14. + T lymphocytes after infection with HCV
15. Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients
16. Critical role for alpha/beta and gamma interferons in persistence of LCMV by clonal exhaustion of CTL
17. Skewed maturation of memory HIV-specific CD8 T lymphocytes
18. HIV-specific CD8(+) T cells produce antiviral cytokines but are impaired in cytolytic function
19. Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections
20. Impairment of CD4(+) T cell responses during chronic virus infection
21. + T cell epitope escape mutant virus selected in vivo
22. CD8(+) lymphocytes from simian immunodeficiency virus-infected rhesus macaques recognize 14 different epitopes bound by the major histocompatibility complex class I molecule mamu-A*01: Implications for vaccine design and testing
23. The HIV-1 regulatory proteins Tat and Rev are frequently targeted by CTL derived from HIV-1 infected individuals
24. Human immunodeficiency virus type 1 -hepatitis C virus coinfection: Intraindividual comparison of cellular immune responses against two persistent viruses
25. Importance of p15 Gagspecific responses to the total gag specific CTL responses
26. Vpr is preferentially targeted by CTL during HIV-1 infection
27. Patterns of immunodominance in HIV-1-specific cytotoxic T lymphocyte responses in two human histocompatibility leukocyte antigens (HLA)-identical siblings with HLA-A*0201 are influenced by epitope mutation
28. Direct ex vivo analysis reveals distinct phenotypic patterns of HIV specific CTL activation in response to therapeutic manipulation of viral load
29. Identification of dynamically distinct subpopulations of T lymphocytes that are differentially affected by HIV
30. Long term kinetics of T cell production in HIV-infected subjects treated with HAART
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32. Effect of coinfection with GB virus C on survival among patients with HIV
33. Infection with GB virus C and reduced mortality among HIV-infected individuals
34. Effect of a single amino acid change in MHC class I molecules on the rate of progression to AIDS
35. HLA-B35 is associated with accelerated progression to AIDS
36. HLA-B*5703 independently associated with slower HIV-1 disease progression in Rwandan women
37. Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses
38. Evolution and transmission of stable CTL escape mutations in HIV infection
39. Original antigenic sin impairs the CTL response against variant viruses
40. Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes
41. Simian immunodeficiency virus-specific cytotoxic T lymphocytes and protection against challenge in rhesus macaques immunized with a live attenuated simian immunodeficiency virus vaccine
42. Induction of AIDS virus-specific CTL activity in fresh, unstimulated peripheral blood lymphocytes from rhesus macaques vaccinated with a DNA prime/modified vaccinia virus Ankara boost regimen
43. Augmentation of immune responses to HIV-1 and simian immunodeficiency virus DNA vaccines by IL-2/Ig plasmid administration in rhesus monkeys
44. Cytotoxic T lymphocytes recognize structurally diverse, clade-specific and cross-reactive peptides in human immunodeficiency virus type-1 gag through HLA-B53
45. Differential narrow focusing of immunodominant human immunodeficiency virus gag-specific cytotoxic T-lymphocyte responses in infected African and caucasoid adults and children
46. Identification of human immunodeficiency virus type 1 subtype C Gag-, Tat-, Rev-, and Nef-specific elispot-based cytotoxic T-lymphocyte responses for AIDS vaccine design
47. Late escape from an immunodominant CTL response associated with progression to AIDS
48. Population dynamics of immune responses to persistent viruses
49. Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level