HIV-1 binding to CD4 on CD4+CD25+ regulatory T cells enhances their suppressive function and induces them to home to, and accumulate in, peripheral and mucosal lymphoid tissues: An additional mechanism of immunosuppression

International Immunology

Volumn 21, Issue 3, 2009, Pages 283-294

  Ji, Jiaxiang ^a   Cloyd, Miles W ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

CD4+CD25+ regulatory T cells; HIV 1; Homing; Suppressive function

Indexed keywords

CD4 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; GLYCOPROTEIN GP 120; INTERLEUKIN 2 RECEPTOR ALPHA; L SELECTIN; TRANSCRIPTION FACTOR FOXP3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL MIGRATION; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNE DEFICIENCY; IN VITRO STUDY; LYMPH NODE; LYMPHOCYTE FUNCTION; LYMPHOCYTE HOMING; LYMPHOID TISSUE; MOUSE; NONHUMAN; PERSISTENT VIRUS INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REGULATORY T LYMPHOCYTE; VIRUS ATTACHMENT; VIRUS CELL INTERACTION; VIRUS IMMUNITY;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD4; APOPTOSIS; CELL DIFFERENTIATION; CELL MOVEMENT; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; HIV ENVELOPE PROTEIN GP120; HIV INFECTIONS; HIV-1; HUMANS; IMMUNE TOLERANCE; INTEGRINS; L-SELECTIN; LYMPH NODES; MICE; MICE, SCID; MUCOUS MEMBRANE; PROTEIN BINDING; RECEPTORS, NERVE GROWTH FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR; T-LYMPHOCYTES, REGULATORY;

EID: 61349156886     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxn146     Document Type: Article

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