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Volumn 3, Issue 6, 2008, Pages

Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia

(21)  Perfettini, Jean Luc a   Nardacci, Roberta b   Bourouba, Mehdi a   Subra, Frédéric c   Gros, Laurent c   Séror, Claire a   Manic, Gwenola a   Rosselli, Filippo a   Amendola, Alessandra b   Masdehors, Peggy d   Chessa, Luciana e   Novelli, Giuseppe f   Ojcius, David M g   Siwicki, Jan Konrad h   Chechlinska, Magdalena h   Auclair, Christian c   Regueiro, José R i   de Thé, Hugues j   Gougeon, Marie Lise d   Piacentini, Mauro b,f   more..


Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 6 (1 THIANTHRENYL) 4 PYRANONE; ATM PROTEIN; CD4 ANTIGEN; DNA; HISTONE H2AX; INTEGRASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NIBRIN; PROTEIN P53; SERINE; TUMOR SUPPRESSOR PROTEIN; VIRUS ENVELOPE PROTEIN; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; HISTONE; PROTEIN SERINE THREONINE KINASE;

EID: 49349092475     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002458     Document Type: Article
Times cited : (36)

References (54)
  • 1
    • 3042740594 scopus 로고    scopus 로고
    • The changing face of the HIV epidemic in western Europe: What are the implications for public health policies?
    • Hamers FF, Downs AM (2004) The changing face of the HIV epidemic in western Europe: what are the implications for public health policies? Lancet 364: 83-94.
    • (2004) Lancet , vol.364 , pp. 83-94
    • Hamers, F.F.1    Downs, A.M.2
  • 2
    • 4644311698 scopus 로고    scopus 로고
    • Progressive multifocal leukencephalopathy in patients on highly active antiretroviral therapy: Survival and risk factors of death
    • Wyen C, Hoffmann C, Schmeisser N, Wohrmann A, Qurishi N, et al. (2004) Progressive multifocal leukencephalopathy in patients on highly active antiretroviral therapy: survival and risk factors of death. J Acquir Immune Defic Syndr 37: 1263-1268.
    • (2004) J Acquir Immune Defic Syndr , vol.37 , pp. 1263-1268
    • Wyen, C.1    Hoffmann, C.2    Schmeisser, N.3    Wohrmann, A.4    Qurishi, N.5
  • 3
    • 20444395039 scopus 로고    scopus 로고
    • Highly active antiretroviral therapy and human immunodeficiency virus encephalitis
    • Cook JE, Dasgupta S, Middaugh LD, Terry EC, Gorry PR, et al. (2005) Highly active antiretroviral therapy and human immunodeficiency virus encephalitis. Ann Neurol 57: 795-803.
    • (2005) Ann Neurol , vol.57 , pp. 795-803
    • Cook, J.E.1    Dasgupta, S.2    Middaugh, L.D.3    Terry, E.C.4    Gorry, P.R.5
  • 4
    • 0034329318 scopus 로고    scopus 로고
    • Mechanisms of HIV-associated lymphocyte apoptosis
    • Badley AD, Pilon AA, Landay A, Lynch DH (2000) Mechanisms of HIV-associated lymphocyte apoptosis. Blood 96: 2951-2964.
    • (2000) Blood , vol.96 , pp. 2951-2964
    • Badley, A.D.1    Pilon, A.A.2    Landay, A.3    Lynch, D.H.4
  • 5
    • 0028939951 scopus 로고
    • Apoptosis in HIV infection
    • Pantaleo G, Fauci AS (1995) Apoptosis in HIV infection. Nat Med 1: 118-120.
    • (1995) Nat Med , vol.1 , pp. 118-120
    • Pantaleo, G.1    Fauci, A.S.2
  • 6
    • 0038725688 scopus 로고    scopus 로고
    • Apoptosis as an HIV strategy to escape immune attack
    • Gougeon ML (2003) Apoptosis as an HIV strategy to escape immune attack. Nat Rev Immunol 3: 392-404.
    • (2003) Nat Rev Immunol , vol.3 , pp. 392-404
    • Gougeon, M.L.1
  • 7
    • 22744453481 scopus 로고    scopus 로고
    • To kill or be killed: How HIV exhausts the immune system
    • Gougeon ML (2005) To kill or be killed: how HIV exhausts the immune system. Cell Death Differ 12 Suppl 1: 845-854.
    • (2005) Cell Death Differ , vol.12 , Issue.SUPPL. 1 , pp. 845-854
    • Gougeon, M.L.1
  • 8
    • 0031950195 scopus 로고    scopus 로고
    • Vpr stimulates viral expression and induces cell killing in human immunodeficiency virus type 1-infected dividing Jurkat T cells
    • Yao XJ, Mouland AJ, Subbramanian RA, Forget J, Rougeau N, et al. (1998) Vpr stimulates viral expression and induces cell killing in human immunodeficiency virus type 1-infected dividing Jurkat T cells. J Virol 72: 4686-4693.
    • (1998) J Virol , vol.72 , pp. 4686-4693
    • Yao, X.J.1    Mouland, A.J.2    Subbramanian, R.A.3    Forget, J.4    Rougeau, N.5
  • 9
    • 33044503759 scopus 로고    scopus 로고
    • Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis
    • Lum JJ, Cohen OJ, Nie Z, Weaver JG, Gomez TS, et al. (2003) Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis. J Clin Invest 111: 1547-1554.
    • (2003) J Clin Invest , vol.111 , pp. 1547-1554
    • Lum, J.J.1    Cohen, O.J.2    Nie, Z.3    Weaver, J.G.4    Gomez, T.S.5
  • 10
    • 0034715893 scopus 로고    scopus 로고
    • Apoptosis of syncytia induced by the HIV-1-envelope glycoprotein complex: Influence of cell shape and size
    • Ferri KF, Jacotot E, Leduc P, Geuskens M, Ingber DE, et al. (2000) Apoptosis of syncytia induced by the HIV-1-envelope glycoprotein complex: influence of cell shape and size. Exp Cell Res 261: 119-126.
    • (2000) Exp Cell Res , vol.261 , pp. 119-126
    • Ferri, K.F.1    Jacotot, E.2    Leduc, P.3    Geuskens, M.4    Ingber, D.E.5
  • 11
    • 0035970310 scopus 로고    scopus 로고
    • Syncytium formation amplifies apoptotic signals: A new view on apoptosis in HIV infection in vitro
    • Scheller C, Jassoy C (2001) Syncytium formation amplifies apoptotic signals: a new view on apoptosis in HIV infection in vitro. Virology 282: 48-55.
    • (2001) Virology , vol.282 , pp. 48-55
    • Scheller, C.1    Jassoy, C.2
  • 12
    • 0033994315 scopus 로고    scopus 로고
    • Envelope glycoprotein determinants of increased fusogenicity in a pathogenic simian-human immunodeficiency virus (SHIV-KB9) passaged in vivo
    • Etemad-Moghadam B, Sun Y, Nicholson EK, Fernandes M, Liou K, et al. (2000) Envelope glycoprotein determinants of increased fusogenicity in a pathogenic simian-human immunodeficiency virus (SHIV-KB9) passaged in vivo. J Virol 74: 4433-4440.
    • (2000) J Virol , vol.74 , pp. 4433-4440
    • Etemad-Moghadam, B.1    Sun, Y.2    Nicholson, E.K.3    Fernandes, M.4    Liou, K.5
  • 13
    • 0343416248 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 pathogenesis in SCID-hu mice correlates with syncytium-inducing phenotype and viral replication
    • Camerini D, Su HP, Gamez-Torre G, Johnson ML, Zack JA, et al. (2000) Human immunodeficiency virus type 1 pathogenesis in SCID-hu mice correlates with syncytium-inducing phenotype and viral replication. J Virol 74: 3196-3204.
    • (2000) J Virol , vol.74 , pp. 3196-3204
    • Camerini, D.1    Su, H.P.2    Gamez-Torre, G.3    Johnson, M.L.4    Zack, J.A.5
  • 14
    • 0033961745 scopus 로고    scopus 로고
    • In vivo HIV-1 infection of CD45RA(+)CD4(+) T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4(+) T cell decline
    • Blaak H, van't Wout AB, Brouwer M, Hooibrink B, Hovenkamp E, et al. (2000) In vivo HIV-1 infection of CD45RA(+)CD4(+) T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4(+) T cell decline. Proc Natl Acad Sci U S A 97: 1269-1274.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1269-1274
    • Blaak, H.1    van't Wout, A.B.2    Brouwer, M.3    Hooibrink, B.4    Hovenkamp, E.5
  • 15
    • 0036787097 scopus 로고    scopus 로고
    • Relevance of viral phenotype in the early AIDS outcome of pediatric HIV-1 primary infection
    • Kopka J, Batalla M, Mangano A, Mecikovsky D, Bologna R, et al. (2002) Relevance of viral phenotype in the early AIDS outcome of pediatric HIV-1 primary infection. Pediatr Res 52: 475-480.
    • (2002) Pediatr Res , vol.52 , pp. 475-480
    • Kopka, J.1    Batalla, M.2    Mangano, A.3    Mecikovsky, D.4    Bologna, R.5
  • 16
    • 0000969952 scopus 로고
    • Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients
    • Wiley CA, Schrier RD, Nelson JA, Lampert PW, Oldstone MB (1986) Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients. Proc Natl Acad Sci U S A 83: 7089-7093.
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 7089-7093
    • Wiley, C.A.1    Schrier, R.D.2    Nelson, J.A.3    Lampert, P.W.4    Oldstone, M.B.5
  • 19
    • 4344579518 scopus 로고    scopus 로고
    • NF-kappaB and p53 are the dominant apoptosis-inducing transcription factors elicited by the HIV-1 envelope
    • Perfettini JL, Roumier T, Castedo M, Larochette N, Boya P, et al. (2004) NF-kappaB and p53 are the dominant apoptosis-inducing transcription factors elicited by the HIV-1 envelope. J Exp Med 199: 629-640.
    • (2004) J Exp Med , vol.199 , pp. 629-640
    • Perfettini, J.L.1    Roumier, T.2    Castedo, M.3    Larochette, N.4    Boya, P.5
  • 20
    • 13244260955 scopus 로고    scopus 로고
    • Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope
    • Perfettini JL, Castedo M, Nardacci R, Ciccosanti F, Boya P, et al. (2005) Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope. J Exp Med 201: 279-289.
    • (2005) J Exp Med , vol.201 , pp. 279-289
    • Perfettini, J.L.1    Castedo, M.2    Nardacci, R.3    Ciccosanti, F.4    Boya, P.5
  • 21
    • 24044493578 scopus 로고    scopus 로고
    • Characterization of cell death pathways in human immunodeficiency virus-associated encephalitis
    • Nardacci R, Antinori A, Larocca LM, Arena V, Amendola A, et al. (2005) Characterization of cell death pathways in human immunodeficiency virus-associated encephalitis. Am J Pathol 167: 695-704.
    • (2005) Am J Pathol , vol.167 , pp. 695-704
    • Nardacci, R.1    Antinori, A.2    Larocca, L.M.3    Arena, V.4    Amendola, A.5
  • 22
    • 9444270386 scopus 로고    scopus 로고
    • HIV associated neurodegeneration requires p53 in neurons and microglia
    • Garden GA, Guo W, Jayadev S, Tun C, Balcaitis S, et al. (2004) HIV associated neurodegeneration requires p53 in neurons and microglia. Faseb J 18: 1141-1143.
    • (2004) Faseb J , vol.18 , pp. 1141-1143
    • Garden, G.A.1    Guo, W.2    Jayadev, S.3    Tun, C.4    Balcaitis, S.5
  • 23
    • 35648945862 scopus 로고    scopus 로고
    • The glial response to CNS HIV infection includes p53 activation and increased expression of p53 target genes
    • Jayadev S, Yun B, Nguyen H, Yokoo H, Morrison RS, et al. (2007) The glial response to CNS HIV infection includes p53 activation and increased expression of p53 target genes. J Neuroimmune Pharmacol 2: 359-370.
    • (2007) J Neuroimmune Pharmacol , vol.2 , pp. 359-370
    • Jayadev, S.1    Yun, B.2    Nguyen, H.3    Yokoo, H.4    Morrison, R.S.5
  • 24
    • 18444416812 scopus 로고    scopus 로고
    • Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope
    • Castedo M, Roumier T, Blanco J, Ferri KF, Barretina J, et al. (2002) Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope. Embo J 21: 4070-4080.
    • (2002) Embo J , vol.21 , pp. 4070-4080
    • Castedo, M.1    Roumier, T.2    Blanco, J.3    Ferri, K.F.4    Barretina, J.5
  • 25
    • 0035887446 scopus 로고    scopus 로고
    • Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/ FKBP12-rapamycin-associated protein-mediated p53 phosphorylation
    • Castedo M, Ferri KF, Blanco J, Roumier T, Larochette N, et al. (2001) Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/ FKBP12-rapamycin-associated protein-mediated p53 phosphorylation. J Exp Med 194: 1097-1110.
    • (2001) J Exp Med , vol.194 , pp. 1097-1110
    • Castedo, M.1    Ferri, K.F.2    Blanco, J.3    Roumier, T.4    Larochette, N.5
  • 26
    • 17244367849 scopus 로고    scopus 로고
    • DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
    • Bartkova J, Horejsi Z, Koed K, Kramer A, Tort F, et al. (2005) DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 434: 864-870.
    • (2005) Nature , vol.434 , pp. 864-870
    • Bartkova, J.1    Horejsi, Z.2    Koed, K.3    Kramer, A.4    Tort, F.5
  • 27
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: Safeguarding genome integrity
    • Shiloh Y (2003) ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 3: 155-168.
    • (2003) Nat Rev Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 28
    • 34548414588 scopus 로고    scopus 로고
    • Image-based modeling reveals dynamic redistribution of DNA damage into nuclear sub-domains
    • Costes SV, Ponomarev A, Chen JL, Nguyen D, Cucinotta FA, et al. (2007) Image-based modeling reveals dynamic redistribution of DNA damage into nuclear sub-domains. PLoS Comput Biol 3: e155.
    • (2007) PLoS Comput Biol , vol.3
    • Costes, S.V.1    Ponomarev, A.2    Chen, J.L.3    Nguyen, D.4    Cucinotta, F.A.5
  • 30
    • 33646117239 scopus 로고    scopus 로고
    • Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
    • Bekker-Jensen S, Lukas C, Kitagawa R, Melander F, Kastan MB, et al. (2006) Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J Cell Biol 173: 195-206.
    • (2006) J Cell Biol , vol.173 , pp. 195-206
    • Bekker-Jensen, S.1    Lukas, C.2    Kitagawa, R.3    Melander, F.4    Kastan, M.B.5
  • 31
    • 0035834693 scopus 로고    scopus 로고
    • ATM phosphorylates histone H2AX in response to DNA double-strand breaks
    • Burma S, Chen BP, Murphy M, Kurimasa A, Chen DJ (2001) ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J Biol Chem 276: 42462-42467.
    • (2001) J Biol Chem , vol.276 , pp. 42462-42467
    • Burma, S.1    Chen, B.P.2    Murphy, M.3    Kurimasa, A.4    Chen, D.J.5
  • 32
    • 0043032762 scopus 로고    scopus 로고
    • DNA damage-mediated apoptosis induced by selenium compounds
    • Zhou N, Xiao H, Li TK, Nur EKA, Liu LF (2003) DNA damage-mediated apoptosis induced by selenium compounds. J Biol Chem 278: 29532-29537.
    • (2003) J Biol Chem , vol.278 , pp. 29532-29537
    • Zhou, N.1    Xiao, H.2    Li, T.K.3    Nur, E.K.A.4    Liu, L.F.5
  • 33
    • 18344388668 scopus 로고    scopus 로고
    • Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase
    • Lau A, Swinbank KM, Ahmed PS, Taylor DL, Jackson SP, et al. (2005) Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase. Nat Cell Biol 7: 493-500.
    • (2005) Nat Cell Biol , vol.7 , pp. 493-500
    • Lau, A.1    Swinbank, K.M.2    Ahmed, P.S.3    Taylor, D.L.4    Jackson, S.P.5
  • 35
    • 34447551681 scopus 로고    scopus 로고
    • Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair
    • Berkovich E, Monnat RJ, Jr, Kastan MB (2007) Roles of ATM and NBS1 in chromatin structure modulation and DNA double-strand break repair. Nat Cell Biol 9: 683-690.
    • (2007) Nat Cell Biol , vol.9 , pp. 683-690
    • Berkovich, E.1    Monnat Jr, R.J.2    Kastan, M.B.3
  • 36
  • 38
    • 33745058037 scopus 로고    scopus 로고
    • Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex
    • Dupre A, Boyer-Chatenet L, Gautier J (2006) Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex. Nat Struct Mol Biol 13: 451-457.
    • (2006) Nat Struct Mol Biol , vol.13 , pp. 451-457
    • Dupre, A.1    Boyer-Chatenet, L.2    Gautier, J.3
  • 39
    • 0030994880 scopus 로고    scopus 로고
    • Genotoxicity and mitochondrial damage in human lymphocytic cells chronically exposed to 3′-azido-2′,3′-dideoxythymidine
    • Agarwal RP, Olivero OA (1997) Genotoxicity and mitochondrial damage in human lymphocytic cells chronically exposed to 3′-azido-2′,3′-dideoxythymidine. Mutat Res 390: 223-231.
    • (1997) Mutat Res , vol.390 , pp. 223-231
    • Agarwal, R.P.1    Olivero, O.A.2
  • 40
    • 17444420810 scopus 로고    scopus 로고
    • Inhibition of HIV-1 replication by caffeine and caffeine-related methylxanthines
    • Nunnari G, Argyris E, Fang J, Mehlman KE, Pomerantz RJ, et al. (2005) Inhibition of HIV-1 replication by caffeine and caffeine-related methylxanthines. Virology 335: 177-184.
    • (2005) Virology , vol.335 , pp. 177-184
    • Nunnari, G.1    Argyris, E.2    Fang, J.3    Mehlman, K.E.4    Pomerantz, R.J.5
  • 41
    • 4644351274 scopus 로고    scopus 로고
    • PML nuclear bodies: Dynamic sensors of DNA damage and cellular stress
    • Dellaire G, Bazett-Jones DP (2004) PML nuclear bodies: dynamic sensors of DNA damage and cellular stress. Bioessays 26: 963-977.
    • (2004) Bioessays , vol.26 , pp. 963-977
    • Dellaire, G.1    Bazett-Jones, D.P.2
  • 42
    • 0037066695 scopus 로고    scopus 로고
    • ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation
    • Saito S, Goodarzi AA, Higashimoto Y, Noda Y, Lees-Miller SP, et al. (2002) ATM mediates phosphorylation at multiple p53 sites, including Ser(46), in response to ionizing radiation. J Biol Chem 277: 12491-12494.
    • (2002) J Biol Chem , vol.277 , pp. 12491-12494
    • Saito, S.1    Goodarzi, A.A.2    Higashimoto, Y.3    Noda, Y.4    Lees-Miller, S.P.5
  • 44
    • 0000303499 scopus 로고    scopus 로고
    • ATM associates with and phosphorylates p53: Mapping the region of interaction
    • Khanna KK, Keating KE, Kozlov S, Scott S, Gatei M, et al. (1998) ATM associates with and phosphorylates p53: mapping the region of interaction. Nat Genet 20: 398-400.
    • (1998) Nat Genet , vol.20 , pp. 398-400
    • Khanna, K.K.1    Keating, K.E.2    Kozlov, S.3    Scott, S.4    Gatei, M.5
  • 45
    • 0032508504 scopus 로고    scopus 로고
    • Enhanced phosphorylation of p53 by ATM in response to DNA damage
    • Banin S, Moyal L, Shieh S, Taya Y, Anderson CW, et al. (1998) Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science 281: 1674-1677.
    • (1998) Science , vol.281 , pp. 1674-1677
    • Banin, S.1    Moyal, L.2    Shieh, S.3    Taya, Y.4    Anderson, C.W.5
  • 46
    • 0033625759 scopus 로고    scopus 로고
    • Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest
    • Wang X, McGowan CH, Zhao M, He L, Downey JS, et al. (2000) Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest. Mol Cell Biol 20: 4543-4552.
    • (2000) Mol Cell Biol , vol.20 , pp. 4543-4552
    • Wang, X.1    McGowan, C.H.2    Zhao, M.3    He, L.4    Downey, J.S.5
  • 47
    • 0038037235 scopus 로고    scopus 로고
    • Induction of ATF3 by ionizing radiation is mediated via a signaling pathway that includes ATM, Nibrin1, stress-induced MAPkinases and ATF-2
    • Kool J, Hamdi M, Cornelissen-Steijger P, van der Eb AJ, Terleth C, et al. (2003) Induction of ATF3 by ionizing radiation is mediated via a signaling pathway that includes ATM, Nibrin1, stress-induced MAPkinases and ATF-2. Oncogene 22: 4235-4242.
    • (2003) Oncogene , vol.22 , pp. 4235-4242
    • Kool, J.1    Hamdi, M.2    Cornelissen-Steijger, P.3    van der Eb, A.J.4    Terleth, C.5
  • 48
    • 0141611781 scopus 로고    scopus 로고
    • The ATR-independent DNA replication checkpoint
    • Brown EJ (2003) The ATR-independent DNA replication checkpoint. Cell Cycle 2: 188-189.
    • (2003) Cell Cycle , vol.2 , pp. 188-189
    • Brown, E.J.1
  • 49
    • 0037446871 scopus 로고    scopus 로고
    • Evidence that the retroviral DNA integration process triggers an ATR-dependent DNA damage response
    • Daniel R, Kao G, Taganov K, Greger JG, Favorova O, et al. (2003) Evidence that the retroviral DNA integration process triggers an ATR-dependent DNA damage response. Proc Natl Acad Sci U S A 100: 4778-4783.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 4778-4783
    • Daniel, R.1    Kao, G.2    Taganov, K.3    Greger, J.G.4    Favorova, O.5
  • 50
    • 0037830710 scopus 로고    scopus 로고
    • Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R
    • Roshal M, Kim B, Zhu Y, Nghiem P, Planelles V (2003) Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R. J Biol Chem 278: 25879-25886.
    • (2003) J Biol Chem , vol.278 , pp. 25879-25886
    • Roshal, M.1    Kim, B.2    Zhu, Y.3    Nghiem, P.4    Planelles, V.5
  • 51
    • 6344227897 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation
    • Zimmerman ES, Chen J, Andersen JL, Ardon O, Dehart JL, et al. (2004) Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation. Mol Cell Biol 24: 9286-9294.
    • (2004) Mol Cell Biol , vol.24 , pp. 9286-9294
    • Zimmerman, E.S.1    Chen, J.2    Andersen, J.L.3    Ardon, O.4    Dehart, J.L.5
  • 52
    • 22744450170 scopus 로고    scopus 로고
    • Retroviral DNA integration and the DNA damage response
    • Skalka AM, Katz RA (2005) Retroviral DNA integration and the DNA damage response. Cell Death Differ 12 Suppl 1: 971-978.
    • (2005) Cell Death Differ , vol.12 , Issue.SUPPL. 1 , pp. 971-978
    • Skalka, A.M.1    Katz, R.A.2
  • 53
    • 0034047129 scopus 로고    scopus 로고
    • Membrane and transmembrane signaling in Herpesvirus saimiritransformed human CD4(+) and CD8(+) T lymphocytes is ATM-independent
    • Rivero-Carmena M, Porras O, Pelaez B, Pacheco-Castro A, Gatti RA, et al. (2000) Membrane and transmembrane signaling in Herpesvirus saimiritransformed human CD4(+) and CD8(+) T lymphocytes is ATM-independent. Int Immunol 12: 927-935.
    • (2000) Int Immunol , vol.12 , pp. 927-935
    • Rivero-Carmena, M.1    Porras, O.2    Pelaez, B.3    Pacheco-Castro, A.4    Gatti, R.A.5
  • 54
    • 0037841506 scopus 로고    scopus 로고
    • Telomere maintenance and cell cycle regulation in spontaneously immortalized T-cell lines from Nijmegen breakage syndrome patients
    • Siwicki JK, Degerman S, Chrzanowska KH, Roos G (2003) Telomere maintenance and cell cycle regulation in spontaneously immortalized T-cell lines from Nijmegen breakage syndrome patients. Exp Cell Res 287: 178-189.
    • (2003) Exp Cell Res , vol.287 , pp. 178-189
    • Siwicki, J.K.1    Degerman, S.2    Chrzanowska, K.H.3    Roos, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.