-
1
-
-
0033136302
-
Thymus and autoimmunity production of CD25+CD4+ naturally anergic and suppressive T-cells as a key function of the thymus in maintaining immunologic self-tolerance
-
Itoh M, Takahashi T, Sakaguchi N, et al. Thymus and autoimmunity production of CD25+CD4+ naturally anergic and suppressive T-cells as a key function of the thymus in maintaining immunologic self-tolerance. J Immunol 1999;162:5317-22.
-
(1999)
J Immunol
, vol.162
, pp. 5317-5322
-
-
Itoh, M.1
Takahashi, T.2
Sakaguchi, N.3
-
2
-
-
0033032992
-
Anergic T-cells act as suppressor cells in vitro and in vivo
-
Chai J, Bartok J, Chandler P, et al. Anergic T-cells act as suppressor cells in vitro and in vivo. Eur J Immunol 1999;29:686-92.
-
(1999)
Eur J Immunol
, vol.29
, pp. 686-692
-
-
Chai, J.1
Bartok, J.2
Chandler, P.3
-
4
-
-
0035806289
-
Certified Professionals. CD4+CD25+ suppressor T-cells
-
Shevach E. Certified Professionals. CD4+CD25+ suppressor T-cells. J Exp Med 2001;193:41-5.
-
(2001)
J Exp Med
, vol.193
, pp. 41-45
-
-
Shevach, E.1
-
5
-
-
0035554676
-
Regulatory T-cells in the control of immune pathology
-
Maloy J, Powrie F. Regulatory T-cells in the control of immune pathology. Nature Immunol 2001;2:816-22.
-
(2001)
Nature Immunol
, vol.2
, pp. 816-822
-
-
Maloy, J.1
Powrie, F.2
-
6
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T-cells expressing IL-2 receptor alpha chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T-cells expressing IL-2 receptor alpha chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995;155:1151-64.
-
(1995)
J Immunol
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
7
-
-
0035054606
-
Human C04+CD25+ thymocytes and peripheral T-cells have immunosuppressive activity in vitro
-
Stephens L, Mottet C, Mason D, Powrie F. Human C04+CD25+ thymocytes and peripheral T-cells have immunosuppressive activity in vitro. Eur J Immunol 2001;31:1247-54.
-
(2001)
Eur J Immunol
, vol.31
, pp. 1247-1254
-
-
Stephens, L.1
Mottet, C.2
Mason, D.3
Powrie, F.4
-
8
-
-
0035806290
-
Identification and functional characterization of human CD4+CD25+ T-cells with regulatory properties isolated from peripheral blood
-
Jonuleit H, Schmitt E, Stassen M, Tuettenberg A, Knop J, Enk A. Identification and functional characterization of human CD4+CD25+ T-cells with regulatory properties isolated from peripheral blood. J Exp Med 2001;193:1285-94.
-
(2001)
J Exp Med
, vol.193
, pp. 1285-1294
-
-
Jonuleit, H.1
Schmitt, E.2
Stassen, M.3
Tuettenberg, A.4
Knop, J.5
Enk, A.6
-
9
-
-
0035806323
-
Human CD4+CD25+ Treg cells suppress naive and memory T-cell proliferation and can be expanded in vitro without loss of function
-
Levings M, Sangregorio R, Roncarolo M. Human CD4+CD25+ Treg cells suppress naive and memory T-cell proliferation and can be expanded in vitro without loss of function. J Exp Med 2001; 193:1295-302.
-
(2001)
J Exp Med
, vol.193
, pp. 1295-1302
-
-
Levings, M.1
Sangregorio, R.2
Roncarolo, M.3
-
10
-
-
0142250482
-
T cells under scrutiny
-
Bach F. Regulatory T cells under scrutiny. Nat Rev Immunol 2003; 3:189-98.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 189-198
-
-
Regulatory, B.F.1
-
11
-
-
0033682056
-
B7/CD28 co-stimulation is essential for the homeostasis of CD4+CD25+ immunoregulatory T-cells that control autoimmune diabetes
-
Salomon B, Lenschow D, Rhee L, et al. B7/CD28 co-stimulation is essential for the homeostasis of CD4+CD25+ immunoregulatory T-cells that control autoimmune diabetes. Immunity 2000;12:431-40.
-
(2000)
Immunity
, vol.12
, pp. 431-440
-
-
Salomon, B.1
Lenschow, D.2
Rhee, L.3
-
13
-
-
1642390941
-
Activation requirements for the induction of CD4+CD25+ T-cell suppressor function
-
Thornton A, Piccirillo CA, Shevach E. Activation requirements for the induction of CD4+CD25+ T-cell suppressor function. Eur J Immunol 2004;34:366-76.
-
(2004)
Eur J Immunol
, vol.34
, pp. 366-376
-
-
Thornton, A.1
Piccirillo, C.A.2
Shevach, E.3
-
14
-
-
16844362608
-
Mechanisms of suppression by suppressor T-cells
-
Von Boehmer H. Mechanisms of suppression by suppressor T-cells. Nat Immunol 2005;6:338-44.
-
(2005)
Nat Immunol
, vol.6
, pp. 338-344
-
-
Von Boehmer, H.1
-
15
-
-
1642379813
-
GITR, a member ot the TNF receptor superfamily, is co-stimulatory to mouse T lymphocyte subpopulations
-
Ronchetti S, Zollo D, Bruscoli S, et al. GITR, a member ot the TNF receptor superfamily, is co-stimulatory to mouse T lymphocyte subpopulations. Eur J Immunol 2004;34:613-22.
-
(2004)
Eur J Immunol
, vol.34
, pp. 613-622
-
-
Ronchetti, S.1
Zollo, D.2
Bruscoli, S.3
-
16
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25+CD4+ regulatory cells that control intestinal inflammation
-
Read S, Malmstrom V, Powrie F. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25+CD4+ regulatory cells that control intestinal inflammation. J Exp Med 2000;192:295-302.
-
(2000)
J Exp Med
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
17
-
-
0033853625
-
Naturally anergic and suppressive CD25+CD4+ T-cells as a functionally and phenotypically distinct immunoregulatory T-cell subpopulation
-
Kunisayu Y, Takahashi T, Itoh M, Shimizu J, Toda G, Sakaguchi S. Naturally anergic and suppressive CD25+CD4+ T-cells as a functionally and phenotypically distinct immunoregulatory T-cell subpopulation. Int Immunol 2000;12:1145-55.
-
(2000)
Int Immunol
, vol.12
, pp. 1145-1155
-
-
Kunisayu, Y.1
Takahashi, T.2
Itoh, M.3
Shimizu, J.4
Toda, G.5
Sakaguchi, S.6
-
18
-
-
13944270218
-
CD4+CD25high regulatory T-cells in human autoimmune diabetes
-
Putnam A, Vendrame F, Dolts F, Gottlieb P. CD4+CD25high regulatory T-cells in human autoimmune diabetes. J Autoimmun 2005; 24:55-62.
-
(2005)
J Autoimmun
, vol.24
, pp. 55-62
-
-
Putnam, A.1
Vendrame, F.2
Dolts, F.3
Gottlieb, P.4
-
20
-
-
15244354286
-
Regulatory T-call lineage specification by the forkhead transcription factor Foxp3
-
Fontenot J, Rasmussen J, Williams L, Dooley J, Farr A, Rudensky A. Regulatory T-call lineage specification by the forkhead transcription factor Foxp3. Immunity 2005;22:329-41.
-
(2005)
Immunity
, vol.22
, pp. 329-341
-
-
Fontenot, J.1
Rasmussen, J.2
Williams, L.3
Dooley, J.4
Farr, A.5
Rudensky, A.6
-
21
-
-
33646168597
-
FOXP3: Of mice and men
-
Ziegler S. FOXP3: of mice and men. Annu Rev Immunol 2006; 24:209-26.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 209-226
-
-
Ziegler, S.1
-
22
-
-
33745817085
-
CD127 expression inversely correlates with Foxp3 and suppressive function of human CD4+ Treg cells
-
Liu W, Putnam A, Xu-yu Z, et al. CD127 expression inversely correlates with Foxp3 and suppressive function of human CD4+ Treg cells. J Exp Med 2006;203:1701-11.
-
(2006)
J Exp Med
, vol.203
, pp. 1701-1711
-
-
Liu, W.1
Putnam, A.2
Xu-yu, Z.3
-
23
-
-
18144366988
-
Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+ CD25+ T-cells
-
Baecher-Allan C, Wolf E, Hafler D. Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+ CD25+ T-cells. Clin Immunol 2005;115:10-18.
-
(2005)
Clin Immunol
, vol.115
, pp. 10-18
-
-
Baecher-Allan, C.1
Wolf, E.2
Hafler, D.3
-
24
-
-
20344372648
-
Phenotypic and functional differences between human CD4+CD25+ and type 1 regulatory T-cells
-
Levings M, Roncarolo M. Phenotypic and functional differences between human CD4+CD25+ and type 1 regulatory T-cells. Curr Top Microbiol Immunol 2005;293:303-26.
-
(2005)
Curr Top Microbiol Immunol
, vol.293
, pp. 303-326
-
-
Levings, M.1
Roncarolo, M.2
-
25
-
-
0035284804
-
CD25+CD4+ T-cells regulate the expansion of peripheral CD4 T-cells through the production of IL-10
-
Annacher O, Pimenta-Araujo H, Burlen-Defranoux D, Barbosa T, Cumano A, Bandeira A. CD25+CD4+ T-cells regulate the expansion of peripheral CD4 T-cells through the production of IL-10. J Immunol 2001;166:3008-18.
-
(2001)
J Immunol
, vol.166
, pp. 3008-3018
-
-
Annacher, O.1
Pimenta-Araujo, H.2
Burlen-Defranoux, D.3
Barbosa, T.4
Cumano, A.5
Bandeira, A.6
-
26
-
-
0034844841
-
Oral tolerance: Immune mechanisms and the generation of Th3-type TGFα-sacreting regulatory cells
-
Weiner H. Oral tolerance: immune mechanisms and the generation of Th3-type TGFα-sacreting regulatory cells. Microbes Infect 2001; 3:947-54.
-
(2001)
Microbes Infect
, vol.3
, pp. 947-954
-
-
Weiner, H.1
-
27
-
-
0141796312
-
IGFβ-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
-
Belghith M, Bluestone J, Barriot S, Megret J, Bach J, Chatenoud L. IGFβ-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes. Nat Med 2003; 9:1202-8.
-
(2003)
Nat Med
, vol.9
, pp. 1202-1208
-
-
Belghith, M.1
Bluestone, J.2
Barriot, S.3
Megret, J.4
Bach, J.5
Chatenoud, L.6
-
28
-
-
0024272153
-
Immunologic abnormalities in HIV-infected asymptomatic homosexual men
-
Miedema F, Chantal-Petit A, Terpstra F, et al. Immunologic abnormalities in HIV-infected asymptomatic homosexual men. J Clin Invest 1988;82:1908-14.
-
(1988)
J Clin Invest
, vol.82
, pp. 1908-1914
-
-
Miedema, F.1
Chantal-Petit, A.2
Terpstra, F.3
-
29
-
-
0037105617
-
CD4 T-cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load
-
Sousa A, Carneiro J, Meier-Schellersheim M, Grossman Z, Victorino H. CD4 T-cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load. J Immunol 2002;169:3400-8.
-
(2002)
J Immunol
, vol.169
, pp. 3400-3408
-
-
Sousa, A.1
Carneiro, J.2
Meier-Schellersheim, M.3
Grossman, Z.4
Victorino, H.5
-
30
-
-
0041327667
-
Persistent immune activation in HIV-1 infection is associated with progression to AIDS
-
Hazenberg M, Otto S, van Banthem M, et al. Persistent immune activation in HIV-1 infection is associated with progression to AIDS. AIDS 2003;17:1881-7.
-
(2003)
AIDS
, vol.17
, pp. 1881-1887
-
-
Hazenberg, M.1
Otto, S.2
van Banthem, M.3
-
31
-
-
0036195161
-
CD4+CD25+ immunoregulatory T-cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
-
McHugh R, Whitters M, Piccirillo D, et al. CD4+CD25+ immunoregulatory T-cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity 2002;16:311-23.
-
(2002)
Immunity
, vol.16
, pp. 311-323
-
-
McHugh, R.1
Whitters, M.2
Piccirillo, D.3
-
32
-
-
17644376164
-
CD25+CD4+ regulatory T-cells exert in vitro suppressive activity independent of CTLA-4
-
Kataoka H, Takahashi K, Takase S, et al. CD25+CD4+ regulatory T-cells exert in vitro suppressive activity independent of CTLA-4. Int Immunol 2005;17:421-7.
-
(2005)
Int Immunol
, vol.17
, pp. 421-427
-
-
Kataoka, H.1
Takahashi, K.2
Takase, S.3
-
33
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T-cells
-
Fontenot J, Gavin M, Rudensky A. Foxp3 programs the development and function of CD4+CD25+ regulatory T-cells. Nat Immunol 2003;4:330-6.
-
(2003)
Nat Immunol
, vol.4
, pp. 330-336
-
-
Fontenot, J.1
Gavin, M.2
Rudensky, A.3
-
34
-
-
22144470799
-
In vivo expansion of CD4+CD45RO-CD25+ I-cells expressing Foxp3 in IL2-treatad HIV-infecfed patients
-
Sereti I, Imamichi H, Natarajan V, et al. In vivo expansion of CD4+CD45RO-CD25+ I-cells expressing Foxp3 in IL2-treatad HIV-infecfed patients. J Clin Invest 2005;115:1839-47.
-
(2005)
J Clin Invest
, vol.115
, pp. 1839-1847
-
-
Sereti, I.1
Imamichi, H.2
Natarajan, V.3
-
35
-
-
8644280556
-
HIV-driven expansion of CD4+CD25+ regulatory T-cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients
-
Weiss L, Donkova-Petrini V, Caccavelli L, Balbo M, Carboneil C, Levy Y. HIV-driven expansion of CD4+CD25+ regulatory T-cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients. Blood 2004;104:3249-56.
-
(2004)
Blood
, vol.104
, pp. 3249-3256
-
-
Weiss, L.1
Donkova-Petrini, V.2
Caccavelli, L.3
Balbo, M.4
Carboneil, C.5
Levy, Y.6
-
36
-
-
10744227590
-
Human CD4+CD25+ regulatory cells control T-cell responses to HIV and cytomegalovirus antigens
-
Aandahl E, Michaelsson J, Moretto W, Hecht F, Nixon D. Human CD4+CD25+ regulatory cells control T-cell responses to HIV and cytomegalovirus antigens. J Virol 2004;78:2454-9.
-
(2004)
J Virol
, vol.78
, pp. 2454-2459
-
-
Aandahl, E.1
Michaelsson, J.2
Moretto, W.3
Hecht, F.4
Nixon, D.5
-
37
-
-
20644434609
-
Relationship of CD4+CD25+ regulatory T-cells to immune status in HIV-infected patients
-
Tsunemi S, Iwasaki I, Imado T, et al. Relationship of CD4+CD25+ regulatory T-cells to immune status in HIV-infected patients. AIDS 2005;19:879-86.
-
(2005)
AIDS
, vol.19
, pp. 879-886
-
-
Tsunemi, S.1
Iwasaki, I.2
Imado, T.3
-
38
-
-
33750310898
-
HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS
-
Nilsson J, Boasso A, Andrea Velilla P, et al. HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS. Blood 2006;108:3808-17.
-
(2006)
Blood
, vol.108
, pp. 3808-3817
-
-
Nilsson, J.1
Boasso, A.2
Andrea Velilla, P.3
-
39
-
-
19344374571
-
HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells
-
Oswald-Ritcher K, Grill S, Shariat N, et al. HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells. PLoS Biol 2004;2:955-66.
-
(2004)
PLoS Biol
, vol.2
, pp. 955-966
-
-
Oswald-Ritcher, K.1
Grill, S.2
Shariat, N.3
-
40
-
-
15444363618
-
Depletion of regulatory T-cells in HIV infection is associated with immune activation
-
Eggena M, Barugahare B, Jones N, et al. Depletion of regulatory T-cells in HIV infection is associated with immune activation. J Immunol 2005;174:4407-14.
-
(2005)
J Immunol
, vol.174
, pp. 4407-4414
-
-
Eggena, M.1
Barugahare, B.2
Jones, N.3
-
41
-
-
3543098686
-
CD25+CD4+ regulatory T-cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4+ and CD8+ HIV-specific T-cell immune responses in vitro and are associated with favorable clinical markers of disease status
-
Kinter A, Hennesay M, Bell A, et al. CD25+CD4+ regulatory T-cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4+ and CD8+ HIV-specific T-cell immune responses in vitro and are associated with favorable clinical markers of disease status. J Exp Med 2004;200:331-43.
-
(2004)
J Exp Med
, vol.200
, pp. 331-343
-
-
Kinter, A.1
Hennesay, M.2
Bell, A.3
-
42
-
-
33750320502
-
Mucosal but not peripheral Foxp3+ regulatory T-cells are highly increased in untreated HIV infection and normalize after suppressive HAART
-
Epple H, Loddenkemper C, Kunkel D, et al. Mucosal but not peripheral Foxp3+ regulatory T-cells are highly increased in untreated HIV infection and normalize after suppressive HAART. Blood 2006; 108:3072-8.
-
(2006)
Blood
, vol.108
, pp. 3072-3078
-
-
Epple, H.1
Loddenkemper, C.2
Kunkel, D.3
-
43
-
-
33746675679
-
Foxp3+ regulatory T-cells in antiretroviral-naive HIV patients
-
Montes M, Lewis D, Sanchez C, et al. Foxp3+ regulatory T-cells in antiretroviral-naive HIV patients. AIDS 2006;20:1669-70.
-
(2006)
AIDS
, vol.20
, pp. 1669-1670
-
-
Montes, M.1
Lewis, D.2
Sanchez, C.3
-
44
-
-
17444407451
-
The prevalence of regulatory T-cells in lymphoid tissue is correlated with viral load in HIV-infected patients
-
Anderson J, Boasso A, Nilsson J, et al. The prevalence of regulatory T-cells in lymphoid tissue is correlated with viral load in HIV-infected patients. J Immunol 2005;174:3143-7.
-
(2005)
J Immunol
, vol.174
, pp. 3143-3147
-
-
Anderson, J.1
Boasso, A.2
Nilsson, J.3
-
45
-
-
34248363931
-
Interactions between regulatory T-cells and HIV: A complex balancing act
-
Los Angeles, February 25-28, abstract 159
-
Chougnet C, Velilla P, Nilsson J, Boasso A, Andersson J, Shearer G. Interactions between regulatory T-cells and HIV: a complex balancing act. 14th CROI. Los Angeles, February 25-28 2007 [abstract 159].
-
(2007)
14th CROI
-
-
Chougnet, C.1
Velilla, P.2
Nilsson, J.3
Boasso, A.4
Andersson, J.5
Shearer, G.6
|