Falcipains, plasmodium falciparum cysteine proteases as key drug targets against malaria

Current Medicinal Chemistry

Volumn 18, Issue 10, 2011, Pages 1555-1572

  Teixeira, C ^a,b   Gomes, J R B ^b   Gomes, P ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF AVEIRO   (Portugal)

Author keywords

Cysteine proteases; Drug design; Falcipain inhibitors; Falcipains; Malaria; Plasmodium Falciparum

Indexed keywords

ANTIMALARIAL AGENT; ASPARTIC PROTEINASE; ATOVAQUONE; CHLOROQUINE; CYSTEINE PROTEINASE; FALCIPAIN; FOSMIDOMYCIN; GLYPHOSATE; HEMOGLOBIN; IMMUCILIN H; LEUPEPTIN; METHOTREXATE; NAS 21; NAS 91; PEPSTATIN; PROBENECID; THIOLACTOMYCIN; TRICLOSAN; UNCLASSIFIED DRUG;

ARTICLE; CELL VACUOLE; DEGRADATION; DRUG DESIGN; DRUG EFFICACY; DRUG POTENCY; DRUG TARGETING; GENOME; MALARIA; NONHUMAN; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION; SURVIVAL;

ANIMALS; ANTIMALARIALS; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DRUG DELIVERY SYSTEMS; DRUG DESIGN; HUMANS; MALARIA; PLASMODIUM FALCIPARUM;

EID: 79955015664     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986711795328328     Document Type: Article

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