Model calculations about the influence of protic environments on the alkylation step of epoxide, aziridine, and thiirane based cysteine protease inhibitors

Journal of Physical Chemistry A

Volumn 108, Issue 38, 2004, Pages 7691-7701

  Helten, Holger ^a   Schirmeister, Tanja ^a   Engels, Bernd ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; AMINES; CATALYSIS; ENTROPY; ENZYME INHIBITION; ENZYME KINETICS; MATHEMATICAL MODELS; PH EFFECTS; RATE CONSTANTS; THERMODYNAMICS;

ENZYME INHIBITORS; PROTIC ENVIRONMENTS; PROTON DONORS; REACTION ENERGY;

ENZYMES;

EID: 4944256999     PISSN: 10895639     EISSN: None     Source Type: Journal    
DOI: 10.1021/jp048784g     Document Type: Article

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