Structure-based approach to falcipain-2 inhibitors: Synthesis and biological evaluation of 1,6,7-Trisubstituted dihydroisoquinolines and isoquinolines

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 10, 2003, Pages 2293-2299

  Batra, Sanjay ^a   Sabnis, Yogesh A ^b   Rosenthal, Philip J ^c   Avery, Mitchell A ^b,d  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 BENZYLOXYPHENYL) 6 METHOXY 7 BENZYLOXYISOQUINOLINE; 1 (4 BENZYLOXYPHENYL) 6,7 DIMETHOXYISOQUINOLINE; 1 (4 BENZYLOXYPHENYL) 6,7 METHYLENEDIOXYISOQUINOLINE; 1 (4 HYDROXYPHENYL) 6 METHOXY 7 BENZYLOXYISOQUINOLINE; 1 (4 HYDROXYPHENYL) 6 METHOXY 7 HYDROXYISOQUINOLINE; 1 (4 HYDROXYPHENYL) 6,7 DIMETHOXY 3,4 DIHYDROISOQUINOLINE; 1 (4 HYDROXYPHENYL) 6,7 DIMETHOXYISOQUINOLINE; 1 (4 HYDROXYPHENYL) 6,7 METHYLENEDIOXYISOQUINOLINE; 1 (4 METHOXYPHENYL) 6 METHOXY 7 BENZYLOXY 3,4 DIHYDROISOQUINOLINE; 1 (4 METHOXYPHENYL) 6 METHOXY 7 BENZYLOXYISOQUINOLINE; 1 (4 METHOXYPHENYL) 6 METHOXY 7 HYDROXY 3,4 DIHYDROISOQUINOLINE; 1 (4 METHOXYPHENYL) 6 METHOXY 7 HYDROXYISOQUINOLINE; 1 (4 METHOXYPHENYL) 6,7 DIMETHOXY 3,4 DIHYDROISOQUINOLINE; 1 (4 METHOXYPHENYL) 7 BENZYLOXY 3,4 DIHYDROISOQUINOLINE; CYSTEINE PROTEINASE; FALCIPAIN 2; ISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CORRELATION COEFFICIENT; CYCLIZATION; DEMETHYLATION; DEPROTECTION REACTION; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION;

PLASMODIUM FALCIPARUM;

EID: 0037447948     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(03)00117-2     Document Type: Article

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