Synthesis and evaluation of isatins and thiosemicarbazone derivatives against cruzain, falcipain-2 and rhodesain

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 20, 2003, Pages 3527-3530

  Chiyanzu, Idan ^a   Hansell, Elizabeth ^b   Gut, Jiri ^b   Rosenthal, Philip J ^b   McKerrow, James H ^b   Chibale, Kelly ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYLISATIN; 1 PHENYLISATIN; 5 (TRIFLUOROMETHOXY)ISATIN; 5 BROMOISATIN; 5 CHLOROISATIN; 5 FLUOROISATIN; 5 IODOISATIN; 5 METHYLISATIN; 5 NITROISATIN; 5,7 DIMETHYLISATIN; CRUZIPAIN; FALCIPAIN 2; ISATIN; ISATIN DERIVATIVE; RECOMBINANT PROTEIN; RHODESAIN; THIOSEMICARBAZONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DRUG EFFECT; DRUG SCREENING; DRUG SYNTHESIS; IC 50; PROTEIN FUNCTION; REACTION ANALYSIS; SUBSTITUTION REACTION;

EID: 0141627969     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(03)00756-X     Document Type: Article

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