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Volumn 19, Issue 5, 2002, Pages 765-774
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Homology modeling of falcipain-2: Validation, De Novo ligand design and synthesis of novel inhibitors
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Author keywords
[No Author keywords available]
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Indexed keywords
ANTIINFECTIVE AGENT;
CYSTEINE PROTEINASE;
CYSTEINE PROTEINASE INHIBITOR;
ENZYME INHIBITOR;
ISOQUINOLINE DERIVATIVE;
LIGAND;
SULFONE DERIVATIVE;
VINYL DERIVATIVE;
ARTICLE;
BINDING AFFINITY;
BINDING SITE;
CONCENTRATION RESPONSE;
CONFORMATIONAL TRANSITION;
CRYSTAL STRUCTURE;
DRUG SYNTHESIS;
DRUG TARGETING;
ENZYME ACTIVITY;
ENZYME BINDING;
ENZYME INHIBITION;
ENZYME STRUCTURE;
FALCIPAIN 2 GENE;
GENE;
GENE TARGETING;
GROWTH INHIBITION;
MALARIA;
MOLECULAR MODEL;
NONHUMAN;
PARASITE CULTIVATION;
PLASMODIUM FALCIPARUM;
PRIORITY JOURNAL;
SEQUENCE ANALYSIS;
SEQUENCE HOMOLOGY;
ALGORITHMS;
AMINO ACID SEQUENCE;
ANIMALS;
CYSTEINE ENDOPEPTIDASES;
CYSTEINE PROTEINASE INHIBITORS;
INHIBITORY CONCENTRATION 50;
LIGANDS;
MODELS, CHEMICAL;
MODELS, MOLECULAR;
MOLECULAR SEQUENCE DATA;
PLASMODIUM FALCIPARUM;
PROTEIN BINDING;
PROTEIN CONFORMATION;
SEQUENCE HOMOLOGY, AMINO ACID;
PLASMODIUM FALCIPARUM;
PROTOZOA;
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EID: 0036244780
PISSN: 07391102
EISSN: None
Source Type: Journal
DOI: 10.1080/07391102.2002.10506783 Document Type: Article |
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Times cited : (52)
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References (27)
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