Antifolate-resistant mutants of Plasmodium falciparum dihydrofolate reductase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 4, 1997, Pages 1124-1129

  Sirawaraporn, Worachart ^a   Sathitkul, Tanajit ^a,d   Sirawaraporn, Rachada ^a   Yuthavong, Yongyuth ^a,d   Santi, Daniel V ^b,c  

^a MAHIDOL UNIVERSITY   (Thailand)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY   (Thailand)

Author keywords

cycloguanil; malaria; mutagenesis; pyrimethamine; synthetic gene

Indexed keywords

CYCLOGUANIL; DIHYDROFOLATE REDUCTASE; PYRIMETHAMINE; SYNTHETIC DNA;

ARTICLE; DNA SYNTHESIS; MALARIA; MUTAGENESIS; PLASMODIUM FALCIPARUM; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS;

ANIMALS; ANTIMALARIALS; DRUG RESISTANCE; EVOLUTION; FOLIC ACID ANTAGONISTS; MODELS, GENETIC; MUTAGENESIS, SITE-DIRECTED; PLASMODIUM FALCIPARUM; POINT MUTATION; PYRIMETHAMINE; TETRAHYDROFOLATE DEHYDROGENASE; TRIAZINES;

PLASMODIUM FALCIPARUM;

EID: 0031037364     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.4.1124     Document Type: Article

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