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Volumn 40, Issue 7, 1996, Pages 1600-1603

Antimalarial effects of vinyl sulfone cysteine proteinase inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; BACTERIAL ENZYME; CYSTEINE PROTEINASE INHIBITOR; DIMETHYL SULFOXIDE; FALCIPAIN; HEMOGLOBIN HYDROXYLASE; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE; UNCLASSIFIED DRUG;

EID: 0030011095     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.40.7.1600     Document Type: Article
Times cited : (187)

References (18)
  • 1
    • 0018606732 scopus 로고
    • Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique
    • Desjardins, R. E., C. J. Canfield, J. D. Haynes, and J. D. Chulay. 1979. Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique. Antimicrob. Agents Chemother. 16:710-718.
    • (1979) Antimicrob. Agents Chemother. , vol.16 , pp. 710-718
    • Desjardins, R.E.1    Canfield, C.J.2    Haynes, J.D.3    Chulay, J.D.4
  • 2
    • 8944258935 scopus 로고    scopus 로고
    • Cysteine proteinase inhibitors block early steps in hemoglobin degradation by cultured malaria parasites
    • in press
    • Domínguez, N. D., and P. J. Rosenthal. Cysteine proteinase inhibitors block early steps in hemoglobin degradation by cultured malaria parasites. Blood, in press.
    • Blood
    • Domínguez, N.D.1    Rosenthal, P.J.2
  • 4
    • 0025754304 scopus 로고
    • Hemoglobin degradation in the human malaria pathogen Plasmodium falciparum: A catabolic pathway initiated by a specific aspartic protease
    • Goldberg, D. E., A. F. G. Slater, R. Beavis, B. Chait, A. Cerami, and G. B. Henderson. 1991. Hemoglobin degradation in the human malaria pathogen Plasmodium falciparum: a catabolic pathway initiated by a specific aspartic protease. J. Exp. Med. 173:961-969.
    • (1991) J. Exp. Med. , vol.173 , pp. 961-969
    • Goldberg, D.E.1    Slater, A.F.G.2    Beavis, R.3    Chait, B.4    Cerami, A.5    Henderson, G.B.6
  • 5
    • 0018704491 scopus 로고
    • Synchronization of Plasmodium falciparum erythrocytic stages in culture
    • Lambros, C., and J. P. Vanderberg. 1979. Synchronization of Plasmodium falciparum erythrocytic stages in culture. J. Parasitol. 65:418-420.
    • (1979) J. Parasitol. , vol.65 , pp. 418-420
    • Lambros, C.1    Vanderberg, J.P.2
  • 9
    • 0029099619 scopus 로고
    • Vinyl sulfones as mechanism-based cysteine protease inhibitors
    • Palmer, J. T., D. Rasnick, J. L. Klaus, and D. Brömme. 1995. Vinyl sulfones as mechanism-based cysteine protease inhibitors. J. Med. Chem. 38:3193-3196.
    • (1995) J. Med. Chem. , vol.38 , pp. 3193-3196
    • Palmer, J.T.1    Rasnick, D.2    Klaus, J.L.3    Brömme, D.4
  • 11
    • 0028948564 scopus 로고
    • Plasmodium falciparum: Effects of proteinase inhibitors on globin hydrolysis by cultured malaria parasites
    • Rosenthal, P. J. 1995. Plasmodium falciparum: effects of proteinase inhibitors on globin hydrolysis by cultured malaria parasites. Exp. Parasitol. 80: 272-281.
    • (1995) Exp. Parasitol. , vol.80 , pp. 272-281
    • Rosenthal, P.J.1
  • 12
    • 0027512171 scopus 로고
    • Inhibition of a Plasmodium vinckei cysteine proteinase cures murine malaria
    • Rosenthal, P. J., G. K. Lee, and R. E. Smith. 1993. Inhibition of a Plasmodium vinckei cysteine proteinase cures murine malaria. J. Clin. Invest. 91: 1052-1056.
    • (1993) J. Clin. Invest. , vol.91 , pp. 1052-1056
    • Rosenthal, P.J.1    Lee, G.K.2    Smith, R.E.3
  • 13
    • 0024208917 scopus 로고
    • A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum
    • Rosenthal, P. J., J. H. McKerrow, M. Aikawa, H. Nagasawa, and J. H. Leech. 1988. A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum. J. Clin. Invest. 82:1560-1566.
    • (1988) J. Clin. Invest. , vol.82 , pp. 1560-1566
    • Rosenthal, P.J.1    McKerrow, J.H.2    Aikawa, M.3    Nagasawa, H.4    Leech, J.H.5
  • 14
    • 0024334026 scopus 로고
    • Plasmodium falciparum: Inhibitors of lysosomal cysteine proteinases inhibit a trophozoite proteinase and block parasite development
    • Rosenthal, P. J., J. H. McKerrow, D. Rasnick, and J. H. Leech. 1989. Plasmodium falciparum: inhibitors of lysosomal cysteine proteinases inhibit a trophozoite proteinase and block parasite development. Mol. Biochem. Parasitol. 35:177-184.
    • (1989) Mol. Biochem. Parasitol. , vol.35 , pp. 177-184
    • Rosenthal, P.J.1    McKerrow, J.H.2    Rasnick, D.3    Leech, J.H.4
  • 15
    • 0025719869 scopus 로고
    • Antimalarial effects of peptide inhibitors of a Plasmodium falciparum cysteine proteinase
    • Rosenthal, P. J., W. S. Wollish, J. T. Palmer, and D. Rasnick. 1991. Antimalarial effects of peptide inhibitors of a Plasmodium falciparum cysteine proteinase. J. Clin. Invest. 88:1467-1472.
    • (1991) J. Clin. Invest. , vol.88 , pp. 1467-1472
    • Rosenthal, P.J.1    Wollish, W.S.2    Palmer, J.T.3    Rasnick, D.4
  • 16
    • 0029057887 scopus 로고
    • Functional expression of falcipain, a Plasmodium falciparum cysteine proteinase, supports its role as a malarial hemoglobinase
    • Salas, F., J. Fichmann, G. K. Lee, M. D. Scott, and P. J. Rosenthal. 1915 Functional expression of falcipain, a Plasmodium falciparum cysteine proteinase, supports its role as a malarial hemoglobinase. Infect. Immun. 63: 2120-2125.
    • (1915) Infect. Immun. , vol.63 , pp. 2120-2125
    • Salas, F.1    Fichmann, J.2    Lee, G.K.3    Scott, M.D.4    Rosenthal, P.J.5
  • 17
    • 0026671680 scopus 로고
    • Localization and characterization of hemoglobin-degrading aspartic proteinases from the malarial parasite Plasmodium falciparum
    • Vander Jagt, D. L., L. A. Hunsaker, N. M. Campos, and J. V. Scaletti. 1912. Localization and characterization of hemoglobin-degrading aspartic proteinases from the malarial parasite Plasmodium falciparum. Biochem. Biophys. Acta 1122:256-264.
    • (1912) Biochem. Biophys. Acta , vol.1122 , pp. 256-264
    • Vander Jagt, D.L.1    Hunsaker, L.A.2    Campos, N.M.3    Scaletti, J.V.4
  • 18
    • 0024954937 scopus 로고
    • Disease problems in the Third World
    • Walsh, J. A. 1989. Disease problems in the Third World. Ann. N.Y. Acad. Sci. 569:1-16.
    • (1989) Ann. N.Y. Acad. Sci. , vol.569 , pp. 1-16
    • Walsh, J.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.