-
1
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J: Tumor angiogenesis: therapeutic implications. N Engl. J. Med. 285(21), 1182-1186 (1971).
-
(1971)
N Engl. J. Med.
, vol.285
, Issue.21
, pp. 1182-1186
-
-
Folkman, J.1
-
2
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
DOI 10.1126/science.284.5415.770
-
Artavanis-Tsakonas S, Rand MD, Lake RJ: Notch signaling: cell fate control and signal integration in development. Science 284(5415), 770-776 (1999). (Pubitemid 29291335)
-
(1999)
Science
, vol.284
, Issue.5415
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
3
-
-
34250867977
-
Notch signaling in development and cancer
-
DOI 10.1210/er.2006-0046
-
Bolós V, Grego-Bessa J, de la Pompa JL: Notch signaling in development and cancer. Endocr. Rev. 28(3), 339-363 (2007). (Pubitemid 46984831)
-
(2007)
Endocrine Reviews
, vol.28
, Issue.3
, pp. 339-363
-
-
Bolos, V.1
Grego-Bessa, J.2
De La Pompa, J.L.3
-
4
-
-
57349200481
-
VEGF and endothelial guidance in angiogenic sprouting
-
Gerhardt H: VEGF and endothelial guidance in angiogenic sprouting. Organogenesis 4(4), 241-246 (2008).
-
(2008)
Organogenesis
, vol.4
, Issue.4
, pp. 241-246
-
-
Gerhardt, H.1
-
5
-
-
33747139066
-
Endothelial tubes assemble from intracellular vacuoles in vivo
-
DOI 10.1038/nature04923, PII NATURE04923
-
Kamei M, Saunders WB, Bayless KJ, Dye L, Davis GE, Weinstein BM: Endothelial tubes assemble from intracellular vacuoles in vivo. Nature 442(7101), 453-456 (2006). (Pubitemid 44264794)
-
(2006)
Nature
, vol.442
, Issue.7101
, pp. 453-456
-
-
Kamei, M.1
Brian Saunders, W.2
Bayless, K.J.3
Dye, L.4
Davis, G.E.5
Weinstein, B.M.6
-
6
-
-
59649104201
-
Cellular and molecular mechanisms of vascular lumen formation
-
Iruela-Arispe ML, Davis GE: Cellular and molecular mechanisms of vascular lumen formation. Dev. Cell 16(2), 222-231 (2009).
-
(2009)
Dev. Cell
, vol.16
, Issue.2
, pp. 222-231
-
-
Iruela-Arispe, M.L.1
Davis, G.E.2
-
7
-
-
59649092177
-
The control of vascular integrity by endothelial cell junctions: Molecular basis and pathological impli cations
-
Dejana E, Tournier-Lasserve E, Weinstein BM: The control of vascular integrity by endothelial cell junctions: molecular basis and pathological impli cations. Dev. Cell 16(2), 209-221 (2009).
-
(2009)
Dev. Cell
, vol.16
, Issue.2
, pp. 209-221
-
-
Dejana, E.1
Tournier-Lasserve, E.2
Weinstein, B.M.3
-
8
-
-
33344468704
-
Pericytes and vascular stability Exp
-
Von Tell D, Armulik A, Betsholtz C: Pericytes and vascular stability Exp. Cell Res. 312(5), 623-629 (2006).
-
(2006)
Cell Res.
, vol.312
, Issue.5
, pp. 623-629
-
-
Von Tell, D.1
Armulik, A.2
Betsholtz, C.3
-
9
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
DOI 10.1016/S0092-8674(00)80108-7
-
Hanahan D, Folkman J: Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86(3), 353-364 (1996). (Pubitemid 26272076)
-
(1996)
Cell
, vol.86
, Issue.3
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
10
-
-
0037967272
-
Tumorigenesis and the angiogenic switch
-
DOI 10.1038/nrc1093
-
Bergers G, Benjamin LE: Tumorigenesis and the angiogenic switch. Nat. Rev. Cancer 3(6), 401-410 (2003). (Pubitemid 37328844)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.6
, pp. 401-410
-
-
Bergers, G.1
Benjamin, L.E.2
-
11
-
-
33646107369
-
VEGF receptor signalling-in control of vascular function
-
Olsson AK, Dimberg A, Kreuger J, Claesson-Welsh L: VEGF receptor signalling-in control of vascular function. Nat. Rev. Mol. Cell Biol. 7(5), 359-371 (2006).
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, Issue.5
, pp. 359-371
-
-
Olsson, A.K.1
Dimberg, A.2
Kreuger, J.3
Claesson-Welsh, L.4
-
12
-
-
44649128099
-
The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching
-
DOI 10.1083/jcb.200709114
-
Kappas NC, Zeng G, Chappell JC et al.: The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching. J. Cell Biol. 181(5), 847-858 (2008). (Pubitemid 351786988)
-
(2008)
Journal of Cell Biology
, vol.181
, Issue.5
, pp. 847-858
-
-
Kappas, N.C.1
Zeng, G.2
Chappell, J.C.3
Kearney, J.B.4
Hazarika, S.5
Kallianos, K.G.6
Patterson, C.7
Annex, B.H.8
Bautch, V.L.9
-
13
-
-
34249689753
-
Molecular regulation of angiogenesis and lymphangiogenesis
-
DOI 10.1038/nrm2183, PII NRM2183
-
Adams RH, Alitalo K: Molecular regulation of angiogenesis and lymphangiogenesis. Nat. Rev. Mol. Cell Biol. 8(6), 464-478 (2007). (Pubitemid 46823443)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.6
, pp. 464-478
-
-
Adams, R.H.1
Alitalo, K.2
-
14
-
-
48349129069
-
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation
-
Tammela T, Zarkada G, Wallgard E et al.: Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature 454(7204), 656-660 (2008).
-
(2008)
Nature
, vol.454
, Issue.7204
, pp. 656-660
-
-
Tammela, T.1
Zarkada, G.2
Wallgard, E.3
-
15
-
-
77950855517
-
Expression of the transcription factor HEY1 in glioblastoma: A preliminary clinical study
-
Gaetani P, Hulleman E, Levi D et al.: Expression of the transcription factor HEY1 in glioblastoma: a preliminary clinical study Tumori 96(1), 97-102 (2010).
-
(2010)
Tumori
, vol.96
, Issue.1
, pp. 97-102
-
-
Gaetani, P.1
Hulleman, E.2
Levi, D.3
-
16
-
-
0242405617
-
Endothelial-pericyte interactions in angiogenesis
-
DOI 10.1007/s00441-003-0745-x
-
Gerhardt H, Betsholtz C: Endothelial-pericyte interactions in angiogenesis. Cell Tissue Res. 314(1), 15-23 (2003). (Pubitemid 37409909)
-
(2003)
Cell and Tissue Research
, vol.314
, Issue.1
, pp. 15-23
-
-
Gerhardt, H.1
Betsholtz, C.2
-
17
-
-
27644557532
-
The role of pericytes in blood-vessel formation and maintenance
-
DOI 10.1215/S1152851705000232
-
Bergers G, Song S: The role of pericytes in blood-vessel formation and maintenance. Neuro Oncol. 7(4), 452-464 (2005). (Pubitemid 41555617)
-
(2005)
Neuro-Oncology
, vol.7
, Issue.4
, pp. 452-464
-
-
Bergers, G.1
Song, S.2
-
18
-
-
64249172203
-
The canonical Notch signaling pathway: Unfolding the activation mechanism
-
Kopan R, Ilagan MX: The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 137(2), 216-233 (2009).
-
(2009)
Cell
, vol.137
, Issue.2
, pp. 216-233
-
-
Kopan, R.1
Ilagan, M.X.2
-
19
-
-
79952003637
-
The cell giveth and the cell taketh away: An overview of Notch pathway activation by endocytic traffcking of ligands and receptors
-
Pratt EB, Wentzell JS, Maxson JE, Courter L, Hazelett D, Christian JL: The cell giveth and the cell taketh away: an overview of Notch pathway activation by endocytic traffcking of ligands and receptors. Acta Histochem. 113(3), 248-255 (2011).
-
(2011)
Acta Histochem.
, vol.113
, Issue.3
, pp. 248-255
-
-
Pratt, E.B.1
Wentzell, J.S.2
Maxson, J.E.3
Courter, L.4
Hazelett, D.5
Christian, J.L.6
-
20
-
-
0033868818
-
A novel proteolytic cleavage involved in Notch signaling: The role of the disintegrin-metalloprotease TACE
-
Brou C, Logeat F, Gupta N et al.: A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE. Mol. Cell 5(2), 207-216 (2000). (Pubitemid 30628080)
-
(2000)
Molecular Cell
, vol.5
, Issue.2
, pp. 207-216
-
-
Brou, C.1
Logeat, F.2
Gupta, N.3
Bessia, C.4
LeBail, O.5
Doedens, J.R.6
Cumano, A.7
Roux, P.8
Black, R.A.9
Israel, A.10
-
21
-
-
0033867521
-
A ligand-induced extracellular cleavage regulates γ-secretase-like proteolytic activation of Notch1
-
Mumm JS, Schroeter EH, S axena MT et al.: A ligand-induced extracellular cleavage regulates γ-secretase-like proteolytic activation of Notch1. Mol. Cell 5(2), 197-206 (2000). (Pubitemid 30628079)
-
(2000)
Molecular Cell
, vol.5
, Issue.2
, pp. 197-206
-
-
Mumm, J.S.1
Schroeter, E.H.2
Saxena, M.T.3
Griesemer, A.4
Tian, X.5
Pan, D.J.6
Ray, W.J.7
Kopan, R.8
-
22
-
-
0029085935
-
Signalling downstream of activated mammalian Notch
-
Jarriault S, Brou C, Logeat F, Schroeter EH, Kopan R, Israel A: Signalling downstream of activated mammalian Notch. Nature 377(6547), 355-358 (1995).
-
(1995)
Nature
, vol.377
, Issue.6547
, pp. 355-358
-
-
Jarriault, S.1
Brou, C.2
Logeat, F.3
Schroeter, E.H.4
Kopan, R.5
Israel, A.6
-
23
-
-
0032574993
-
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
-
DOI 10.1038/30756
-
Schroeter EH, Kisslinger JA, Kopan R: Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 393(6683), 382-386 (1998). (Pubitemid 28269713)
-
(1998)
Nature
, vol.393
, Issue.6683
, pp. 382-386
-
-
Schroeter, E.H.1
Kisslinger, J.A.2
Kopan, R.3
-
24
-
-
33644749306
-
Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes
-
DOI 10.1016/j.cell.2005.12.037, PII S009286740600122X
-
Nam Y, Sliz P, Song L, Aster JC, Blacklow SC: Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes. Cell 124(5), 973-983 (2006). (Pubitemid 43344237)
-
(2006)
Cell
, vol.124
, Issue.5
, pp. 973-983
-
-
Nam, Y.1
Sliz, P.2
Song, L.3
Aster, J.C.4
Blacklow, S.C.5
-
25
-
-
0034729722
-
Mastermind is a putative activator for Notch
-
Petcherski AG, Kimble J: Mastermind is a putative activator for Notch. Curr. Biol. 10(13), R471-R473 (2000).
-
(2000)
Curr. Biol.
, vol.10
, Issue.13
-
-
Petcherski, A.G.1
Kimble, J.2
-
26
-
-
0033662392
-
MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for Notch receptors
-
Wu L, Aster JC, Blacklow SC, Lake R, Artavanis-Tsakonas S, Griffn JD: MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for Notch receptors. Nat. Genet. 26(4), 484-489 (2000).
-
(2000)
Nat. Genet.
, vol.26
, Issue.4
, pp. 484-489
-
-
Wu, L.1
Aster, J.C.2
Blacklow, S.C.3
Lake, R.4
Artavanis-Tsakonas, S.5
Griffn, J.D.6
-
27
-
-
0036837899
-
Identifcation of a family of mastermind-like transcriptional coactivators for mammalian notch receptors
-
Wu L, Sun T, Kobayashi K, Gao P, Griffn JD: Identifcation of a family of mastermind-like transcriptional coactivators for mammalian notch receptors. Mol. Cell Biol. 22(21), 7688-7700 (2002).
-
(2002)
Mol. Cell Biol.
, vol.22
, Issue.21
, pp. 7688-7700
-
-
Wu, L.1
Sun, T.2
Kobayashi, K.3
Gao, P.4
Griffn, J.D.5
-
28
-
-
0037363922
-
HES and HERP families: Multiple effectors of the Notch signaling pathway
-
DOI 10.1002/jcp.10208
-
Iso T, Kedes L, Hamamori Y: HES and HERP families: multiple effectors of the Notch signaling pathway. J. Cell Physiol. 194(3), 237-255 (2003). (Pubitemid 36176887)
-
(2003)
Journal of Cellular Physiology
, vol.194
, Issue.3
, pp. 237-255
-
-
Iso, T.1
Kedes, L.2
Hamamori, Y.3
-
29
-
-
0034778258
-
Notch signaling is required for arterial-venous differentiation during embryonic vascular development
-
Lawson ND, Scheer N, Pham VN et al.: Notch signaling is required for arterial-venous differentiation during embryonic vascular developme nt. Development 128(19), 3675-3683 (2001). (Pubitemid 32998917)
-
(2001)
Development
, vol.128
, Issue.19
, pp. 3675-3683
-
-
Lawson, N.D.1
Scheer, N.2
Pham, V.N.3
Kim, C.-H.4
Chitnis, A.B.5
Campos-Ortega, J.A.6
Weinstein, B.M.7
-
30
-
-
33847764587
-
Crossing paths with Notch in the hyper-network
-
DOI 10.1016/j.ceb.2007.02.012, PII S0955067407000269
-
Hurlbut GD, Kankel MW, Lake RJ, Artavanis-Tsakonas S: Crossing paths with Notch in the hyper-network. Curr. Opin. Cell Biol. 19(2), 166-175 (2007). (Pubitemid 46386408)
-
(2007)
Current Opinion in Cell Biology
, vol.19
, Issue.2
, pp. 166-175
-
-
Hurlbut, G.D.1
Kankel, M.W.2
Lake, R.J.3
Artavanis-Tsakonas, S.4
-
31
-
-
34250209506
-
Notch signaling in blood vessels: Who is talking to whom about what?
-
DOI 10.1161/01.RES.0000266408.42939.e4, PII 0000301220070608000007
-
Hofmann JJ, Iruela-Arispe ML: Notch signaling in blood vessels: who is talking to whom about what? Circ Res. 100(11), 1556-1568 (2007). (Pubitemid 46897259)
-
(2007)
Circulation Research
, vol.100
, Issue.11
, pp. 1556-1568
-
-
Hofmann, J.J.1
Iruela-Arispe, M.L.2
-
32
-
-
0037390452
-
Notch signaling in vascular development
-
DOI 10.1161/01.ATV.0000060892.81529.8F
-
Iso T, Hamamori Y, Kedes L: Notch signaling in vascular development. Arterioscler. Thromb. Vasc Biol. 23(4), 543-553 (2003). (Pubitemid 36438065)
-
(2003)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.23
, Issue.4
, pp. 543-553
-
-
Iso, T.1
Hamamori, Y.2
Kedes, L.3
-
33
-
-
0035753241
-
Delta4, an endothelial specific Notch ligand expressed at sites of physiological and tumor angiogenesis
-
Mailhos C, Modlich U, Lewis J, Harris A, Bicknell R, Ish-Horowicz D: Delta4, an endothelial specifc notch ligand expressed at sites of physiological and tumor angiogenesis. Differentiation 69(2-3), 135-144 (2001). (Pubitemid 33755062)
-
(2001)
Differentiation
, vol.69
, Issue.2-3
, pp. 135-144
-
-
Mailhos, C.1
Modlich, U.2
Lewis, J.3
Harris, A.4
Bicknell, R.5
Ish-Horowicz, D.6
-
34
-
-
8644290828
-
Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development
-
DOI 10.1073/pnas.0407290101
-
Gale NW, Dominguez MG, Noguera I et al.: Haploinsuffciency of Delta-like 4 l igand results in embryonic lethality due to major defects in arterial and vascular development. Proc Natl Acad. Sci. USA 101(45), 15949-15954 (2004). (Pubitemid 39507907)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.45
, pp. 15949-15954
-
-
Gale, N.W.1
Dominguez, M.G.2
Noguera, I.3
Pan, L.4
Hughes, V.5
Valenzuela, D.M.6
Murphy, A.J.7
Adams, N.C.8
Lin, H.C.9
Holash, J.10
Thurston, G.11
Yancopoulos, G.D.12
-
35
-
-
5444242184
-
Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants
-
DOI 10.1101/gad.1239204
-
Krebs LT, Shutter JR, Tanigaki K, Honjo T, Stark KL, Gridley T: Haploinsuffcient lethality and formation of arteriovenous malformations in Notch pathway mutants. Genes Dev. 18(20), 2469-2473 (2004). (Pubitemid 39362888)
-
(2004)
Genes and Development
, vol.18
, Issue.20
, pp. 2469-2473
-
-
Krebs, L.T.1
Shutter, J.R.2
Tanigaki, K.3
Honjo, T.4
Stark, K.L.5
Gridley, T.6
-
36
-
-
59649084735
-
Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli
-
Benedito R, Trindade A, Hirashima M et al.: Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli. BMC Dev. Biol. 8, 117 (2008).
-
(2008)
BMC Dev. Biol.
, vol.8
, pp. 117
-
-
Benedito, R.1
Trindade, A.2
Hirashima, M.3
-
37
-
-
5444261424
-
Dosage-sensitive requirement for mouse Dll4 in artery development
-
DOI 10.1101/gad.1239004
-
Duarte A, Hirashima M, Benedito R et al.: Dosage-sensitive requirement for mouse Dll4 in artery development. Genes Dev. 18(20), 2474-2478 (2004). (Pubitemid 39362889)
-
(2004)
Genes and Development
, vol.18
, Issue.20
, pp. 2474-2478
-
-
Duarte, A.1
Hirashima, M.2
Benedito, R.3
Trindade, A.4
Diniz, P.5
Bekman, E.6
Costa, L.7
Henrique, D.8
Rossant, J.9
-
38
-
-
66449123068
-
The Notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis
-
Benedito R, Roca C, Sorensen I et al.: The Notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis. Cell 137(6), 1124-1135 (2009).
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1124-1135
-
-
Benedito, R.1
Roca, C.2
Sorensen, I.3
-
39
-
-
0032897080
-
Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1
-
Xue Y, Gao X, Lindsell CE et al.: Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1. Hum. Mol. Genet. 8(5), 723-730 (1999). (Pubitemid 29189039)
-
(1999)
Human Molecular Genetics
, vol.8
, Issue.5
, pp. 723-730
-
-
Xue, Y.1
Gao, X.2
Lindsell, C.E.3
Norton, C.R.4
Chang, B.5
Hicks, C.6
Gendron-Maguire, M.7
Rand, E.B.8
Weinmaster, G.9
Gridley, T.10
-
40
-
-
41149156903
-
Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development
-
DOI 10.1073/pnas.0709663105
-
High FA, Lu MM, Pear WS, Loomes KM, Kaestner KH, Epstein JA: Endo thelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development. Proc Natl Acad. Sci. USA 105(6), 1955-1959 (2008). (Pubitemid 351439446)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.6
, pp. 1955-1959
-
-
High, F.A.1
Min, M.L.2
Pear, W.S.3
Loomes, K.M.4
Kaestner, K.H.5
Epstein, J.A.6
-
41
-
-
0034212710
-
Notch signaling is essential for vascular morphogenesis in mice
-
Krebs LT, Xue Y, Norton CR et al.: Notch signaling is essential for vascular morphogenesis in mice. Genes Dev. 14(11), 1343-1352 (2000). (Pubitemid 30397078)
-
(2000)
Genes and Development
, vol.14
, Issue.11
, pp. 1343-1352
-
-
Krebs, L.T.1
Xue, Y.2
Norton, C.R.3
Shutter, J.R.4
Maguire, M.5
Sundberg, J.P.6
Gallahan, D.7
Closson, V.8
Kitajewski, J.9
Callahan, R.10
Smith, G.H.11
Stark, K.L.12
Gridley, T.13
-
42
-
-
17144403287
-
Essential role of endothelial Notch1 in angiogenesis
-
DOI 10.1161/01.CIR.0000160870.93058.DD
-
Limbourg FP, Takeshita K, Radtke F, Bronson RT, Chin MT, Liao JK: Essential role of endothelial Notch1 in angiogenesis. Circulation 111(14), 1826-1832 (2005). (Pubitemid 40525149)
-
(2005)
Circulation
, vol.111
, Issue.14
, pp. 1826-1832
-
-
Limbourg, F.P.1
Takeshita, K.2
Radtke, F.3
Bronson, R.T.4
Chin, M.T.5
Liao, J.K.6
-
43
-
-
0035826844
-
Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium
-
DOI 10.1073/pnas.091584598
-
Uyttendaele H, Ho J, Rossant J, Kitajewski J: Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium. Proc Natl Acad. Sci. USA 98(10), 5643-5648 (2001). (Pubitemid 32435695)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.10
, pp. 5643-5648
-
-
Uyttendaele, H.1
Ho, J.2
Rossant, J.3
Kitajewski, J.4
-
44
-
-
1942498907
-
The Notch target genes Hey1 and Hey2 are required for embryonic vascular development
-
DOI 10.1101/gad.291004
-
Fischer A, Schumacher N, Maier M, Sendtner M, Gessler M: The Notch target genes HEY1 and HEY2 are required for embryonic vascular development. Genes Dev. 18(8), 901-911 (2004). (Pubitemid 38529659)
-
(2004)
Genes and Development
, vol.18
, Issue.8
, pp. 901-911
-
-
Fischer, A.1
Schumacher, N.2
Maier, M.3
Sendtner, M.4
Gessler, M.5
-
45
-
-
33846040204
-
Critical role of endothelial Notch1 signaling in postnatal angiogenesis
-
DOI 10.1161/01.RES.0000254788.47304.6e, PII 0000301220070105000011
-
Takeshita K, Satoh M, Ii M et al.: Critical role of endothelial Notch1 signaling in postnatal angiogenesis. Circ Res. 100(1), 70-78 (2007). (Pubitemid 46066775)
-
(2007)
Circulation Research
, vol.100
, Issue.1
, pp. 70-78
-
-
Takeshita, K.1
Satoh, M.2
Ii, M.3
Silver, M.4
Limbourg, F.P.5
Mukai, Y.6
Rikitake, Y.7
Radtke, F.8
Gridley, T.9
Losordo, D.W.10
Liao, J.K.11
-
46
-
-
58249091885
-
VEGF and Notch signaling: The yin and yang of angiogenic sprouting
-
Hellstrom M, Phng LK, Gerhardt H: VEGF and Notch signaling: the yin and yang of angiogenic sprouting. Cell Adh. Migr. 1(3), 133-136 (2007).
-
(2007)
Cell Adh. Migr.
, vol.1
, Issue.3
, pp. 133-136
-
-
Hellstrom, M.1
Phng, L.K.2
Gerhardt, H.3
-
47
-
-
33847635620
-
Delta-like ligand 4 (DII4) is induced by VEGF as a negative regulator of angiogenic sprouting
-
DOI 10.1073/pnas.0611206104
-
Lobov IB, Renard RA, Papadopoulos N et al.: Delta-li ke ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting. Proc Natl Acad. Sci. USA 104(9), 3219-3224 (2007). (Pubitemid 46364140)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.9
, pp. 3219-3224
-
-
Lobov, I.B.1
Renard, R.A.2
Papadopoulos, N.3
Gale, N.W.4
Thurston, G.5
Yancopoulos, G.D.6
Wiegand, S.J.7
-
48
-
-
39149123515
-
Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells
-
DOI 10.1016/j.mvr.2007.06.006, PII S0026286207000805
-
Harrington LS, Sainson RC, Williams CK et al.: Regulation of mul tiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells. Microvasc Res. 75(2), 144-154 (2008). (Pubitemid 351249857)
-
(2008)
Microvascular Research
, vol.75
, Issue.2
, pp. 144-154
-
-
Harrington, L.S.1
Sainson, R.C.A.2
Williams, C.K.3
Taylor, J.M.4
Shi, W.5
Li, J.-L.6
Harris, A.L.7
-
49
-
-
33847039645
-
Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries
-
DOI 10.1038/nature05577, PII NATURE05577
-
Siekmann AF, Lawson ND: Notch signalling limits angiogenic cell behaviour in developing zebrafsh arteries. Nature 445(7129), 781-784 (2007). (Pubitemid 46279717)
-
(2007)
Nature
, vol.445
, Issue.7129
, pp. 781-784
-
-
Siekmann, A.F.1
Lawson, N.D.2
-
50
-
-
33847607880
-
The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching
-
DOI 10.1073/pnas.0611177104
-
Suchting S, Freitas C, Le Noble F et al.: The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel b ranching. Proc Natl Acad. Sci. USA 104(9), 3225-3230 (2007). (Pubitemid 46364141)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.9
, pp. 3225-3230
-
-
Suchting, S.1
Freitas, C.2
Le Noble, F.3
Benedito, R.4
Breant, C.5
Duarte, A.6
Eichmann, A.7
-
51
-
-
52649121738
-
Overexpression of Delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos
-
Trindade A, Kumar SR, Scehnet JS et al.: Overexpression of Delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos. Blood 112(5), 1720-1729 (2008).
-
(2008)
Blood
, vol.112
, Issue.5
, pp. 1720-1729
-
-
Trindade, A.1
Kumar, S.R.2
Scehnet, J.S.3
-
52
-
-
76049091646
-
Delta-like ligand 4 plays a critical role in pericyte/vascular smooth muscle cell formation during vasculogenesis and tumor vessel expansion in Ewing 's sarcoma
-
Schadler KL, Zweidler-Mckay PA, Guan H, Kleinerman ES: Delta-like ligand 4 plays a critical role in pericyte/vascular smooth muscle cell formation during vasculogenesis and tumor vessel expansion in Ewing 's sarcoma. Clin. Cancer Res. 16(3), 848-856 (2010).
-
(2010)
Clin. Cancer Res.
, vol.16
, Issue.3
, pp. 848-856
-
-
Schadler, K.L.1
Zweidler-Mckay, P.A.2
Guan, H.3
Kleinerman, E.S.4
-
53
-
-
22244460522
-
Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling
-
DOI 10.1016/j.ccr.2005.06.004, PII S1535610805001923
-
Zeng Q, Li S, Chepeha DB et al.: Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling. Cancer Cell 8(1), 13-23 (2005). (Pubitemid 40991811)
-
(2005)
Cancer Cell
, vol.8
, Issue.1
, pp. 13-23
-
-
Zeng, Q.1
Li, S.2
Chepeha, D.B.3
Giordano, T.J.4
Li, J.5
Zhang, H.6
Polverini, P.J.7
Nor, J.8
Kitajewski, J.9
Wang, C.-Y.10
-
54
-
-
3543137628
-
Papillomavirus-mediated neoplastic progression is associated with reciprocal changes in Jagged1 and Manic Fringe expression linked to Notch activation
-
DOI 10.1128/JVI.78.16.8687-8700.2004
-
Veeraraghavalu K, Pett M, Kumar RV et al.: Papillomavirus-mediated neoplastic progression is associated with reciprocal changes in Jagged1 and Manic Fringe expression linked to notch activation. J. Virol. 78(16), 8687-8700 (2004). (Pubitemid 39025134)
-
(2004)
Journal of Virology
, vol.78
, Issue.16
, pp. 8687-8700
-
-
Veeraraghavalu, K.1
Pett, M.2
Kumar, R.V.3
Nair, P.4
Rangarajan, A.5
Stanley, M.A.6
Krishna, S.7
-
55
-
-
19944365553
-
Complementation of human papillomavirus type 16 E6 and E7 by Jagged1-specific Notch1-phosphatidylinositol 3-kinase signaling involves pleiotropic oncogenic functions independent of CBF1;Su(H);Lag-1 activation
-
DOI 10.1128/JVI.79.12.7889-7898.2005
-
Veeraraghavalu K, Subbaiah VK, Srivastava S, Chakrabarti O, Syal R, Krishna S: Complementation of human papillomavirus type 16 E6 and E7 by Jagged1-specifc N otch1-phosphatidylinositol 3-kinase signaling involves pleiotropic oncogenic functions independent of CBF1;Su(H);Lag-1 activation. J. Virol. 79(12), 7889-7898 (2005). (Pubitemid 40756825)
-
(2005)
Journal of Virology
, vol.79
, Issue.12
, pp. 7889-7898
-
-
Veeraraghavalu, K.1
Subbaiah, V.K.2
Srivastava, S.3
Chakrabarti, O.4
Syal, R.5
Krishna, S.6
-
56
-
-
33846392694
-
Coexpression of Notch1 and NF-κB signaling pathway components in human cervical cancer progression
-
DOI 10.1016/j.ygyno.2006.08.054, PII S0090825806006901
-
Ramdass B, Maliekal TT, Lakshmi S et al.: Coexpression of Notch1 and NF-κB signaling pathway components in human cervical cancer progression. Gynecol. Oncol. 104(2), 352-361 (2007). (Pubitemid 46135657)
-
(2007)
Gynecologic Oncology
, vol.104
, Issue.2
, pp. 352-361
-
-
Ramdass, B.1
Maliekal, T.T.2
Lakshmi, S.3
Rehman, M.4
Rema, P.5
Nair, P.6
Mukherjee, G.7
Reddy, B.K.M.8
Krishna, S.9
Radhakrishna Pillai, M.10
-
57
-
-
4744358492
-
Cip1 repression
-
DOI 10.1128/MCB.24.20.8813-8822.2004
-
Noseda M, Chang L, Mclean G et al.: Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression. Mol. Cell Biol. 24(20), 8813-8822 (2004). (Pubitemid 39313888)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.20
, pp. 8813-8822
-
-
Noseda, M.1
Chang, L.2
McLean, G.3
Grim, J.E.4
Clurman, B.E.5
Smith, L.L.6
Karsan, A.7
-
58
-
-
50849100996
-
The many facets of Notch ligands
-
D'Souza B, Miyamoto A, Weinmaster G: The many facets of Notch ligands. Oncogene 27(38), 5148-5167 (2008).
-
(2008)
Oncogene
, vol.27
, Issue.38
, pp. 5148-5167
-
-
D'Souza, B.1
Miyamoto, A.2
Weinmaster, G.3
-
59
-
-
24944506696
-
High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival
-
DOI 10.1158/0008-5472.CAN-05-1069
-
Reedijk M, Odorcic S, Chang L et al.: High-level coexpression of Jag1 and Notch1 is observed in human breast cancer and is associated with p oor overall survival. Cancer Res. 65(18), 8530-8537 (2005). (Pubitemid 41330622)
-
(2005)
Cancer Research
, vol.65
, Issue.18
, pp. 8530-8537
-
-
Reedijk, M.1
Odorcic, S.2
Chang, L.3
Zhang, H.4
Miller, N.5
McCready, D.R.6
Lockwood, G.7
Sean, E.8
-
60
-
-
78049473992
-
Association of high levels of Jagged-1 and Notch-1 expression with poor prognosis in head and neck cancer
-
Lin JT, Chen MK, Yeh KT et al.: Association of high levels of Jagged-1 and Notch-1 expression with poor prognosis in head and neck cancer. Ann. Surg. Oncol. 17, 2976-2983 (2010).
-
(2010)
Ann. Surg. Oncol.
, vol.17
, pp. 2976-2983
-
-
Lin, J.T.1
Chen, M.K.2
Yeh, K.T.3
-
61
-
-
43149112757
-
Involvement of notch signaling in wound healing
-
Chigurupati S, Arumugam TV, Son TG et al.: Involvement of notch signaling in wound healing. PLoS One 2(11), E1167 (2007).
-
(2007)
PLoS One
, vol.2
, Issue.11
-
-
Chigurupati, S.1
Arumugam, T.V.2
Son, T.G.3
-
62
-
-
34247236574
-
Stem and progenitor cells in skeletal muscle development, maintenance, and therapy
-
DOI 10.1038/mt.sj.6300145, PII 6300145
-
Peault B, Rudnicki M, Torrente Y et al.: Stem and progenitor cells in skeletal muscle development, maintenance, and therapy. Mol. Ther. 15(5), 867-877 (2007). (Pubitemid 46621645)
-
(2007)
Molecular Therapy
, vol.15
, Issue.5
, pp. 867-877
-
-
Peault, B.1
Rudnicki, M.2
Torrente, Y.3
Cossu, G.4
Tremblay, J.P.5
Partridge, T.6
Gussoni, E.7
Kunkel, L.M.8
Huard, J.9
-
63
-
-
49449110100
-
Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice
-
Murphy PA, Lam MT, Wu X et al.: Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice. Proc Natl Acad. Sci. USA 105(31), 10901-10906 (2008).
-
(2008)
Proc Natl Acad. Sci. USA
, vol.105
, Issue.31
, pp. 10901-10906
-
-
Murphy, P.A.1
Lam, M.T.2
Wu, X.3
-
64
-
-
33846627870
-
Notch expression patterns in the retina: An eye on receptor-ligand distribution during angiogenesis
-
DOI 10.1016/j.modgep.2006.11.002, PII S1567133X06001943
-
Hofmann JJ, Luisa Iruela-Arispe M: Notch expression patterns in the retina: an eye on receptor-ligand distribution during angiogenesis. Gene Expr. Patterns 7(4), 461-470 (2007). (Pubitemid 46177950)
-
(2007)
Gene Expression Patterns
, vol.7
, Issue.4
, pp. 461-470
-
-
Hofmann, J.J.1
Luisa Iruela-Arispe, M.2
-
65
-
-
67049108093
-
Dll1-mediated Notch activation regulates endothelial identity in mouse fetal arteries
-
Sorensen I, Adams RH, Gossler A: Dll1-mediated Notch activation regulates endothelial identity in mouse fetal arteries. Blood 113(22), 5680-5688 (2009).
-
(2009)
Blood
, vol.113
, Issue.22
, pp. 5680-5688
-
-
Sorensen, I.1
Adams, R.H.2
Gossler, A.3
-
66
-
-
0034817456
-
Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels
-
DOI 10.1016/S0925-4773(01)00469-5, PII S0925477301004695
-
Villa N, Walker L, Lindsell CE, Gasson J, Iruela-Arispe ML, Weinmaster G: Vascular expression of Notch p athway receptors and ligands is restricted to arterial vessels. Mech. Dev. 108(1-2), 161-164 (2001). (Pubitemid 32918185)
-
(2001)
Mechanisms of Development
, vol.108
, Issue.1-2
, pp. 161-164
-
-
Villa, N.1
Walker, L.2
Lindsell, C.E.3
Gasson, J.4
Iruela-Arispe, M.L.5
Weinmaster, G.6
-
67
-
-
21244442600
-
CADASIL mutations impair Notch3 glycosylation by Fringe
-
DOI 10.1093/hmg/ddi171
-
Arboleda-Velasquez JF, Rampal R, Fung E et al.: CADASIL mutations impair Notch3 glycosylation by Fringe. Hum. Mol. Genet. 14(12), 1631-1639 (2005). (Pubitemid 40895515)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.12
, pp. 1631-1639
-
-
Arboleda-Velasquez, J.F.1
Rampal, R.2
Fung, E.3
Darland, D.C.4
Liu, M.5
Martinez, M.C.6
Donahue, C.P.7
Navarro-Gonzalez, M.F.8
Libby, P.9
D'Amore, P.A.10
Aikawa, M.11
Haltiwanger, R.S.12
Kosik, K.S.13
-
69
-
-
0030914459
-
Mutations in the human Jagged1 gene are responsible for Alagille syndrome
-
Oda T, Elkahloun AG, Pike BL et al.: Mutations in the human Jagged1 gene are responsible for Alagille syndrome. Nat. Genet. 16(3), 235-242 (1997).
-
(1997)
Nat. Genet.
, vol.16
, Issue.3
, pp. 235-242
-
-
Oda, T.1
Elkahloun, A.G.2
Pike, B.L.3
-
70
-
-
1642271395
-
Vascular anomalies in alagille syndrome: A significant cause of morbidity and mortality
-
DOI 10.1161/01.CIR.0000121361.01862.A4
-
Kamath BM, Spinner NB, Emerick KM et al.: Vascular anomalies in Alagille syndrome: a signifcant cause of morbidity and mortality. Circulation 109(11), 1354-1358 (2004). (Pubitemid 38387820)
-
(2004)
Circulation
, vol.109
, Issue.11
, pp. 1354-1358
-
-
Kamath, B.M.1
Spinner, N.B.2
Emerick, K.M.3
Chudley, A.E.4
Booth, C.5
Piccoli, D.A.6
Krantz, I.D.7
-
71
-
-
0034674896
-
Chromosome 19 translocation, overexpression of Notch3, and human lung cancer
-
Dang TP, Gazdar AF, Virmani AK et al.: Chromosome 19 translocation, overexpression of Notch3, and human lung cancer. J. Natl Cancer Inst. 92(16), 1355-1357 (2000). (Pubitemid 30660597)
-
(2000)
Journal of the National Cancer Institute
, vol.92
, Issue.16
, pp. 1355-1357
-
-
Dang, T.P.1
Gazdar, A.F.2
Virmani, A.K.3
Sepetavec, T.4
Hande, K.R.5
Minna, J.D.6
Roberts, J.R.7
Carbone, D.P.8
-
72
-
-
7244250027
-
Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis
-
DOI 10.1083/jcb.200406140
-
Pece S, Serresi M, Santolini E et al.: Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis. J. Cell Biol. 167(2), 215-221 (2004). (Pubitemid 39435065)
-
(2004)
Journal of Cell Biology
, vol.167
, Issue.2
, pp. 215-221
-
-
Pece, S.1
Serresi, M.2
Santolini, E.3
Capra, M.4
Hulleman, E.5
Galimberti, V.6
Zurrida, S.7
Maisonneuve, P.8
Viale, G.9
Di Fiore, P.P.10
-
73
-
-
66149129233
-
Inhibition of Notch signaling by γ secretase inhibitor en gages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells
-
Rao SS, O'Neil J, Liberator CD et al.: Inhibition of Notch signaling by γ secretase inhibitor en gages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells. Cancer Res. 69(7), 3060-3068 (2009).
-
(2009)
Cancer Res.
, vol.69
, Issue.7
, pp. 3060-3068
-
-
Rao, S.S.1
O'Neil, J.2
Liberator, C.D.3
-
74
-
-
70849123789
-
Down-regulation of the Notch pathway mediated by a γ-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia
-
Tammam J, Ware C, Efferson C et al.: Down-regulation of the Notch pathway mediated by a γ-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia. Br. J. Pharmacol. 158(5), 1183-1195 (2009).
-
(2009)
Br. J. Pharmacol.
, vol.158
, Issue.5
, pp. 1183-1195
-
-
Tammam, J.1
Ware, C.2
Efferson, C.3
-
75
-
-
20544460148
-
Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
-
DOI 10.1038/nature03659
-
Van Es JH, Van Gijn ME, Riccio O et al.: N otch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 435(7044), 959-963 (2005). (Pubitemid 40896322)
-
(2005)
Nature
, vol.435
, Issue.7044
, pp. 959-963
-
-
Van Es, J.H.1
Van Gijn, M.E.2
Riccio, O.3
Van Den Born, M.4
Vooijs, M.5
Begthel, H.6
Cozijnsen, M.7
Robine, S.8
Winton, D.J.9
Radtke, F.10
Clevers, H.11
-
76
-
-
77954670218
-
Targeting Dll4 in tumors shows preclinical activity but potentially signifcant toxicity
-
Li JL, Jubb AM, Harris AL: Targeting Dll4 in tumors shows preclinical activity but potentially signifcant toxicity. Future Oncol. 6(7), 1099-1103 (2010).
-
(2010)
Future Oncol.
, vol.6
, Issue.7
, pp. 1099-1103
-
-
Li, J.L.1
Jubb, A.M.2
Harris, A.L.3
-
77
-
-
77955952841
-
Prognostic signifcance of Notch 3 gene expression in ovarian serous carcinoma
-
Jung SG, Kwon YD, Song JA et al.: Prognostic signifcance of Notch 3 gene expression in ovarian serous carcinoma. Cancer Sci. 101(9), 1977-1983 (2010).
-
(2010)
Cancer Sci.
, vol.101
, Issue.9
, pp. 1977-1983
-
-
Jung, S.G.1
Kwon, Y.D.2
Song, J.A.3
-
78
-
-
77949309280
-
Notch 1 signaling is active in ovarian cancer
-
Rose SL, Kunnimalaiyaan M, Drenzek J, Seiler N: Notch 1 signaling is active in ovarian cancer. Gynecol. Oncol. 117(1), 130-133 (2010).
-
(2010)
Gynecol. Oncol.
, vol.117
, Issue.1
, pp. 130-133
-
-
Rose, S.L.1
Kunnimalaiyaan, M.2
Drenzek, J.3
Seiler, N.4
-
79
-
-
79951773786
-
Notch1 expression correlates with tumor differentiation status in ovarian carcinoma
-
Wang M, Wang J, Wang L, Wu L, Xin X: Notch1 expression correlates with tumor differentiation status in ovarian carcinoma. Med. Oncol. 27(4), 1329-1335 (2010).
-
(2010)
Med. Oncol.
, vol.27
, Issue.4
, pp. 1329-1335
-
-
Wang, M.1
Wang, J.2
Wang, L.3
Wu, L.4
Xin, X.5
-
80
-
-
59049088446
-
Activation of Notch signaling in human colon adenocarcinoma
-
Reedijk M, Odorcic S, Zhang H et al.: Activation of Notch signaling in human colon adenocarcinoma. Int. J. Oncol. 33(6), 1223-1229 (2008).
-
(2008)
Int. J. Oncol.
, vol.33
, Issue.6
, pp. 1223-1229
-
-
Reedijk, M.1
Odorcic, S.2
Zhang, H.3
-
81
-
-
76049110053
-
Alterations of the Notch pathway in lung cancer
-
Westhoff B, Colaluca IN, DArio G et al.: Alterations of the Notch pathway in lung cancer. Proc Natl Acad. Sci. USA 106(52), 22293-22298 (2009).
-
(2009)
Proc Natl Acad. Sci. USA
, vol.106
, Issue.52
, pp. 22293-22298
-
-
Westhoff, B.1
Colaluca, I.N.2
Dario, G.3
-
82
-
-
76549084826
-
Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor
-
Harrison H, Farnie G, Howell SJ et al.: Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor. Cancer Res. 70(2), 709-718 (2010).
-
(2010)
Cancer Res.
, vol.70
, Issue.2
, pp. 709-718
-
-
Harrison, H.1
Farnie, G.2
Howell, S.J.3
-
83
-
-
77952668917
-
Regulation of Notch signaling by reciprocal inhibition of HES1 and Deltex 1 and its role in osteosarcoma invasiveness
-
Zhang P, Yang Y, Nolo R, Zweidler-Mckay PA, Hughes DP: Regulation of Notch signaling by reciprocal inhibition of HES1 and Deltex 1 and its role in osteosarcoma invasiveness. Oncogene 29(20), 2916-2926 (2010).
-
(2010)
Oncogene
, vol.29
, Issue.20
, pp. 2916-2926
-
-
Zhang, P.1
Yang, Y.2
Nolo, R.3
Zweidler-Mckay, P.A.4
Hughes, D.P.5
-
84
-
-
77749333021
-
Upregulation of Notch pathway molecules in oral squamous cell carcinoma
-
Hijioka H, Setoguchi T, Miyawaki A et al.: Upregulation of Notch pathway molecules in oral squamous cell carcinoma. Int. J. Oncol. 36(4), 817-822 (2010).
-
(2010)
Int. J. Oncol.
, vol.36
, Issue.4
, pp. 817-822
-
-
Hijioka, H.1
Setoguchi, T.2
Miyawaki, A.3
-
85
-
-
77950797954
-
AKT-mTOR signaling is involved in Notch-1-mediated glioma cell survival and proliferation
-
Zhao N, Guo Y, Zhang M, Lin L, Zheng Z: AKT-mTOR signaling is involved in Notch-1-mediated glioma cell survival and proliferation. Oncol. Rep. 23(5), 1443-1447 (2010).
-
(2010)
Oncol. Rep.
, vol.23
, Issue.5
, pp. 1443-1447
-
-
Zhao, N.1
Guo, Y.2
Zhang, M.3
Lin, L.4
Zheng, Z.5
-
87
-
-
77957096339
-
Notch 1 as a potential therapeutic target in cutaneous T-cell lymphoma
-
Kamstrup MR, Gjerdrum LM, Biskup E et al.: Notch 1 as a potential therapeutic target in cutaneous T-cell lymphoma. Blood 116(14), 2504-2512 (2010).
-
(2010)
Blood
, vol.116
, Issue.14
, pp. 2504-2512
-
-
Kamstrup, M.R.1
Gjerdrum, L.M.2
Biskup, E.3
-
88
-
-
77955463319
-
Cerebral cavernous malformation protein CCM1 inhibit s sprouting angiogenesis by activating Delta-Notch signaling
-
Wustehube J, Bartol A, Liebler SS et al.: Cerebral cavernous malformation protein CCM1 inhibit s sprouting angiogenesis by activating Delta-Notch signaling. Proc Natl Acad. Sci. USA 107(28), 12640-12645 (2010).
-
(2010)
Proc Natl Acad. Sci. USA
, vol.107
, Issue.28
, pp. 12640-12645
-
-
Wustehube, J.1
Bartol, A.2
Liebler, S.S.3
-
89
-
-
33845877157
-
Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis
-
DOI 10.1038/nature05355, PII NATURE05355
-
Noguera-Troise I, Daly C, Papadopoulos NJ et al.: Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis. Nature 444(7122), 1032-1037 (2006). (Pubitemid 46018516)
-
(2006)
Nature
, vol.444
, Issue.7122
, pp. 1032-1037
-
-
Noguera-Troise, I.1
Daly, C.2
Papadopoulos, N.J.3
Coetzee, S.4
Boland, P.5
Gale, N.W.6
Chieh Lin, H.7
Yancopoulos, G.D.8
Thurston, G.9
-
90
-
-
33845907380
-
Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis
-
DOI 10.1038/nature05313, PII NATURE05313
-
Ridgway J, Zhang G, Wu Y et al.: Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis. Nature 444(7122), 1083-1087 (2006). (Pubitemid 46018529)
-
(2006)
Nature
, vol.444
, Issue.7122
, pp. 1083-1087
-
-
Ridgway, J.1
Zhang, G.2
Wu, Y.3
Stawicki, S.4
Liang, W.-C.5
Chanthery, Y.6
Kowalski, J.7
Watts, R.J.8
Callahan, C.9
Kasman, I.10
Singh, M.11
Chien, M.12
Tan, C.13
Hongo, J.-A.S.14
De Sauvage, F.15
Plowman, G.16
Yan, M.17
-
91
-
-
34247479498
-
Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion
-
DOI 10.1182/blood-2006-12-063933
-
Scehnet JS, Jiang W, Kumar SR et al.: Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion. Blood 109(11), 4753-4760 (2007). (Pubitemid 46827768)
-
(2007)
Blood
, vol.109
, Issue.11
, pp. 4753-4760
-
-
Scehnet, J.S.1
Jiang, W.2
Kumar, S.R.3
Krasnoperov, V.4
Trindade, A.5
Benedito, R.6
Djokovic, D.7
Borges, C.8
Ley, E.J.9
Duarte, A.10
Gill, P.S.11
-
92
-
-
77955221280
-
Blockade of Delta-like ligand 4 signaling inhibits both growth and angiogenesis of pancreatic cancer
-
Oishi H, Sunamura M, Egawa S et al.: Blockade of Delta-like ligand 4 signaling inhibits both growth and angiogenesis of pancreatic cancer. Pancreas 39(6), 897-903 (2010).
-
(2010)
Pancreas
, vol.39
, Issue.6
, pp. 897-903
-
-
Oishi, H.1
Sunamura, M.2
Egawa, S.3
-
93
-
-
67849124654
-
Dll4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency
-
Hoey T, Yen WC, Axelrod F et al.: Dll4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency. Cell Stem Cell 5(2), 168-177 (2009).
-
(2009)
Cell Stem Cell
, vol.5
, Issue.2
, pp. 168-177
-
-
Hoey, T.1
Yen, W.C.2
Axelrod, F.3
-
94
-
-
37049012486
-
Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo
-
DOI 10.1158/0008-5472.CAN-07-0969
-
Li JL, Sainson RC, Shi W et al.: Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo. Cancer Res. 67(23), 11244-11253 (2007). (Pubitemid 350248550)
-
(2007)
Cancer Research
, vol.67
, Issue.23
, pp. 11244-11253
-
-
Li, J.-L.1
Sainson, R.C.A.2
Shi, W.3
Leek, R.4
Harrington, L.S.5
Preusser, M.6
Biswas, S.7
Turley, H.8
Heikamp, E.9
Hainfellner, J.A.10
Harris, A.L.11
-
95
-
-
77952107920
-
Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis
-
Jubb AM, Buffa FM, Harris AL: Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis. J. Cell Mol. Med. 14(1-2), 18-29 (2009).
-
(2009)
J. Cell Mol. Med.
, vol.14
, Issue.1-2
, pp. 18-29
-
-
Jubb, A.M.1
Buffa, F.M.2
Harris, A.L.3
-
96
-
-
25444506836
-
Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function
-
DOI 10.1158/0008-5472.CAN-05-1208
-
Patel NS, Li JL, Generali D, Poulsom R, Cranston DW, Harris AL: Up-regulation of Delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function. Cancer Res. 65(19), 8690-8697 (2005). (Pubitemid 41377356)
-
(2005)
Cancer Research
, vol.65
, Issue.19
, pp. 8690-8697
-
-
Patel, N.S.1
Li, J.-L.2
Generali, D.3
Poulsom, R.4
Cranston, D.W.5
Harris, A.L.6
-
97
-
-
34250796873
-
Inhibition of notch signaling induces neural differentiation in Ewing sarcoma
-
DOI 10.2353/ajpath.2007.060971
-
Baliko F, Bright T, Poon R, Cohen B, Egan SE, Alman BA: Inhibition of Notch signaling induces neural differentiation in Ewing sarcoma. Am. J. Pathol. 170(5), 1686-1694 (2007). (Pubitemid 47339313)
-
(2007)
American Journal of Pathology
, vol.170
, Issue.5
, pp. 1686-1694
-
-
Baliko, F.1
Bright, T.2
Poon, R.3
Cohen, B.4
Egan, S.E.5
Alman, B.A.6
-
98
-
-
68049129875
-
The Wnt target Jagged-1 mediates the activation of notch signaling by progastrin in human colorectal cancer cells
-
Pannequin J, Bonnans C, Delaunay N et al.: The Wnt target Jagged-1 mediates the activation of notch signaling by progastrin in human colorectal cancer cells. Cancer Res. 69(15), 6065-6073 (2009).
-
(2009)
Cancer Res.
, vol.69
, Issue.15
, pp. 6065-6073
-
-
Pannequin, J.1
Bonnans, C.2
Delaunay, N.3
-
99
-
-
65549140672
-
Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer
-
Rodilla V, Villanueva A, Obrador-Hevia A et al.: Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer. Proc Natl Acad. Sci. USA 106(15), 6315-6320 (2009).
-
(2009)
Proc Natl Acad. Sci. USA
, vol.106
, Issue.15
, pp. 6315-6320
-
-
Rodilla, V.1
Villanueva, A.2
Obrador-Hevia, A.3
-
100
-
-
77149177354
-
Heterogeneity of Jagged1 expression in human and mouse i ntestinal tumors: Implications for targeting Notch signaling
-
Guilmeau S, Flandez M, Mariadason JM, Augenlicht LH: Heterogeneity of Jagged1 expression in human and mouse i ntestinal tumors: implications for targeting Notch signaling. Oncogene 29(7), 992-1002 (2010).
-
(2010)
Oncogene
, vol.29
, Issue.7
, pp. 992-1002
-
-
Guilmeau, S.1
Flandez, M.2
Mariadason, J.M.3
Augenlicht, L.H.4
-
101
-
-
33845595633
-
Notch signaling enhances nestin expression in gliomas
-
DOI 10.1593/neo.06526
-
Shih AH, Holland EC: Notch signaling enhances nestin expression in gliomas. Neoplasia 8(12), 1072-1082 (2006). (Pubitemid 44936157)
-
(2006)
Neoplasia
, vol.8
, Issue.12
, pp. 1072-1082
-
-
Shih, A.H.1
Holland, E.C.2
-
102
-
-
0142259346
-
The role of Notch in tumorigenesis: Oncogene or tumour suppressor
-
Radtke F, Raj K: The role of Notch in tumorigenesis: oncogene or tumour suppressor? Nat. Rev. Cancer 3(10), 756-767 (2003). (Pubitemid 37328814)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.10
, pp. 756-767
-
-
Radtke, F.1
Raj, K.2
-
103
-
-
47949085649
-
A Notch1 ectodomain construct inhibits endothelial notch signaling, tumor growth, and angiogenesis
-
Funahashi Y, Hernandez SL, Das I et al.: A Notch1 ectodomain construct inhibits endothelial notch signaling, tumor growth, and angiogenesis. Cancer Res. 68(12), 4727-4735 (2008).
-
(2008)
Cancer Res.
, vol.68
, Issue.12
, pp. 4727-4735
-
-
Funahashi, Y.1
Hernandez, S.L.2
Das, I.3
-
104
-
-
77953920780
-
MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells
-
Pang RT, Leung CO, Ye TM et al.: MicroRNA-34a suppresses invasion through downregulation of Notch1 and Jagged1 in cervical carcinoma and choriocarcinoma cells. Carcinogenesis 31(6), 1037-1044 (2010).
-
(2010)
Carcinogenesis
, vol.31
, Issue.6
, pp. 1037-1044
-
-
Pang, R.T.1
Leung, C.O.2
Ye, T.M.3
-
105
-
-
51649090695
-
Jag1 expression is associated with a basal phenotype and recurrence in lymph node-negative breast cancer
-
Reedijk M, Pinnaduwage D, Dickson BC et al.: Jag1 expression is associated with a basal phenotype and recurrence in lymph node-negative breast cancer. Breast Cancer Res. Treat. 111(3), 439-448 (2008).
-
(2008)
Breast Cancer Res. Treat.
, vol.111
, Issue.3
, pp. 439-448
-
-
Reedijk, M.1
Pinnaduwage, D.2
Dickson, B.C.3
-
106
-
-
34249098132
-
High-level JAG1 mRNA and protein predict poor outcome in breast cancer
-
DOI 10.1038/modpathol.3800785, PII 3800785
-
Dickson BC, Mulligan AM, Zhang H et al.: High-level JAG1 mRNA and protein predict poor outcome in breast cancer. Mod. Pathol. 20(6), 685-693 (2007). (Pubitemid 46788875)
-
(2007)
Modern Pathology
, vol.20
, Issue.6
, pp. 685-693
-
-
Dickson, B.C.1
Mulligan, A.M.2
Zhang, H.3
Lockwood, G.4
O'Malley, F.P.5
Egan, S.E.6
Reedijk, M.7
-
107
-
-
77349109465
-
Expression of STAT3 and Notch1 is associated with cisplatin resistance in head and neck squamous cell carcinoma
-
Gu F, Ma Y, Zhang Z et al.: Expression of STAT3 and Notch1 is associated with cisplatin resistance in head and neck squamous cell carcinoma. Oncol. Rep. 23(3), 671-676 (2010).
-
(2010)
Oncol. Rep.
, vol.23
, Issue.3
, pp. 671-676
-
-
Gu, F.1
Ma, Y.2
Zhang, Z.3
-
108
-
-
77956165036
-
F-box and WD rep eat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsuffcient suppressor of intestinal tumorigenesis
-
Sancho R, Jandke A, Davis H, Diefenbacher ME, Tomlinson I, Behrens A: F-box and WD rep eat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsuffcient suppressor of intestinal tumorigenesis. Gastroenterology 139(3), 929-941 (2010).
-
(2010)
Gastroenterology
, vol.139
, Issue.3
, pp. 929-941
-
-
Sancho, R.1
Jandke, A.2
Davis, H.3
Diefenbacher, M.E.4
Tomlinson, I.5
Behrens, A.6
-
109
-
-
76749112922
-
Notch signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer
-
Sikandar SS, Pate KT, Ande rson S et al.: Notch signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer. Cancer Res. 70(4), 1469-1478 (2010).
-
(2010)
Cancer Res.
, vol.70
, Issue.4
, pp. 1469-1478
-
-
Sikandar, S.S.1
Pate, K.T.2
Ande Rson, S.3
-
110
-
-
80051754747
-
Notch-1 and Notch-4 receptors as prognostic markers in breast cancer
-
DOI: 10.1177/1066896910362080 Epub ahead of print
-
Yao K, Rizzo P, Rajan P et al.: Notch-1 and Notch-4 receptors as prognostic markers in breast cancer. Int. J. Surg. Pathol. DOI: 10.1177/1066896910362080 (2010) (Epub ahead of print).
-
(2010)
Int. J. Surg. Pathol.
-
-
Yao, K.1
Rizzo, P.2
Rajan, P.3
-
111
-
-
32944470488
-
Aberrant activation of Notch signaling in human breast cancer
-
DOI 10.1158/0008-5472.CAN-05-3054
-
Stylianou S, Clarke RB, Brennan K: Aberrant activation of notch signaling in human breast cancer. Cancer Res. 66(3), 1517-1525 (2006). (Pubitemid 43259933)
-
(2006)
Cancer Research
, vol.66
, Issue.3
, pp. 1517-1525
-
-
Stylianou, S.1
Clarke, R.B.2
Brennan, K.3
-
112
-
-
77955657847
-
Notch1-induced mammary tumor dev elopment is cyclin D1-dependent and correlates with expansion of pre-malignant multipotent duct-limited progenitors
-
Ling H, Sylvestre JR, Jolicoeur P: Notch1-induced mammary tumor dev elopment is cyclin D1-dependent and correlates with expansion of pre-malignant multipotent duct-limited progenitors. Oncogene 29(32), 4543-454 (2010).
-
(2010)
Oncogene
, vol.29
, Issue.32
, pp. 4543-454
-
-
Ling, H.1
Sylvestre, J.R.2
Jolicoeur, P.3
-
113
-
-
20144387679
-
Expression of Notch-1 and its ligands, Delta-like-1 and Jagged=1, is critical for glioma cell survival and proliferation
-
DOI 10.1158/0008-5472.CAN-04-1890
-
Purow BW, Haque RM, Noel MW et al.: Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation. Cancer Res. 65(6), 2353-2363 (2005). (Pubitemid 40490146)
-
(2005)
Cancer Research
, vol.65
, Issue.6
, pp. 2353-2363
-
-
Purow, B.W.1
Haque, R.M.2
Noel, M.W.3
Su, Q.4
Burdick, M.J.5
Lee, J.6
Sundaresan, T.7
Pastorino, S.8
Park, J.K.9
Mikolaenko, I.10
Maric, D.11
Eberhart, C.G.12
Fine, H.A.13
-
114
-
-
77149177354
-
Heterogeneity of Jagged1 expression in human and mouse intestinal tumors: Implications for targeting Notch signaling
-
Guilmeau S, Flandez M, Mariadason JM, Augenlicht LH: Heterogeneity of Jagged1 expression in human and mouse intestinal tumors: implications for targeting Notch signaling. Oncogene 29(7), 992-1002 (2010).
-
(2010)
Oncogene
, vol.29
, Issue.7
, pp. 992-1002
-
-
Guilmeau, S.1
Flandez, M.2
Mariadason, J.M.3
Augenlicht, L.H.4
-
115
-
-
77953158971
-
Notch1 functions as a tumor suppressor in a model of K-ras-induced pancreatic ductal adenocarcinoma
-
Hanlon L, Avila JL, Demarest RM et al.: Notch1 functions as a tumor suppressor in a model of K-ras-induced pancreatic ductal adenocarcinoma. Cancer Res. 70(11), 4280-4286 (2010).
-
(2010)
Cancer Res.
, vol.70
, Issue.11
, pp. 4280-4286
-
-
Hanlon, L.1
Avila, J.L.2
Demarest, R.M.3
-
116
-
-
77951880179
-
Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway
-
Eliasz S, Liang S, Chen Y et al.: Notch-1 stimulates survival of lung adenocarcinoma cells during hypoxia by activating the IGF-1R pathway. Oncogene 29(17), 2488-2498 (2010).
-
(2010)
Oncogene
, vol.29
, Issue.17
, pp. 2488-2498
-
-
Eliasz, S.1
Liang, S.2
Chen, Y.3
-
117
-
-
50849104230
-
Notch tumor suppressor function
-
Dotto GP: Notch tumor suppressor function. Oncogene 27(38), 5115-5123 (2008).
-
(2008)
Oncogene
, vol.27
, Issue.38
, pp. 5115-5123
-
-
Dotto, G.P.1
-
118
-
-
60849132467
-
Notch1 mediates growth suppression of papillary and follicular thyroid cancer cells by histone deacetylase inhibitors
-
Xiao X, Ning L, Chen H: Notch1 mediates growth suppression of papillary and follicular thyroid cancer cells by histone deacetylase inhibitors. Mol. Cancer Ther. 8(2), 350-356 (2009).
-
(2009)
Mol. Cancer Ther.
, vol.8
, Issue.2
, pp. 350-356
-
-
Xiao, X.1
Ning, L.2
Chen, H.3
-
119
-
-
33748359703
-
Up-regulation of endothelial delta-like 4 expression correlates with vessel maturation in bladder cancer
-
DOI 10.1158/1078-0432.CCR-06-0285
-
Patel NS, Dobbie MS, Rochester M et al.: Up-regulation of endothelial delta-like 4 expression correlates with vessel maturation in bladder cancer. Clin. Cancer Res. 12(16), 4836-4844 (2006). (Pubitemid 44338568)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.16
, pp. 4836-4844
-
-
Patel, N.S.1
Dobbie, M.S.2
Rochester, M.3
Steers, G.4
Poulsom, R.5
Le Monnier, K.6
Cranston, D.W.7
Li, J.-L.8
Harris, A.L.9
-
120
-
-
70449517334
-
Expression of Delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer
-
Jubb AM, Turley H, Moeller HC et al.: Expression of Delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer. Br. J. Cancer 101(10), 1749-1757 (2009).
-
(2009)
Br. J. Cancer
, vol.101
, Issue.10
, pp. 1749-1757
-
-
Jubb, A.M.1
Turley, H.2
Moeller, H.C.3
-
121
-
-
52649116986
-
Dll4 activation of Notch signaling reduces tumor vascularity and inhibits tumor growth
-
Segarra M, Williams CK, Sierra Mde L et al.: Dll4 activation of Notch signaling reduces tumor vascularity and inhibits tumor growth. Blood 112(5), 1904-1911 (2008).
-
(2008)
Blood
, vol.112
, Issue.5
, pp. 1904-1911
-
-
Segarra, M.1
Williams, C.K.2
Sierra Mde, L.3
-
122
-
-
51349106560
-
Soluble forms of the Notch ligands Delta1 and Jagged1 promote in vivo tumorigenicity in NIH3T3 fbroblasts with distinct phenotypes
-
Urs S, Roudabush A, O'Neill CF et al.: Soluble forms of the Notch ligands Delta1 and Jagged1 promote in vivo tumorigenicity in NIH3T3 fbroblasts with distinct phenotypes. Am. J. Pathol. 173(3), 865-878 (2008).
-
(2008)
Am. J. Pathol.
, vol.173
, Issue.3
, pp. 865-878
-
-
Urs, S.1
Roudabush, A.2
O'Neill, C.F.3
-
123
-
-
38649125625
-
Rumi Is a CAP10 Domain Glycosyltransferase that Modifies Notch and Is Required for Notch Signaling
-
DOI 10.1016/j.cell.2007.12.016, PII S0092867407016170
-
Acar M, Jafar-Nejad H, Takeuchi H et al.: Rumi is a CAP10 domain glycosyltransferase that modifes Notch and is required for Notch signaling. Cell 132(2), 247-258 (2008). (Pubitemid 351172433)
-
(2008)
Cell
, vol.132
, Issue.2
, pp. 247-258
-
-
Acar, M.1
Jafar-Nejad, H.2
Takeuchi, H.3
Rajan, A.4
Ibrani, D.5
Rana, N.A.6
Pan, H.7
Haltiwanger, R.S.8
Bellen, H.J.9
-
124
-
-
0001395691
-
Fringe is a glycosyltransferase that modifies Notch
-
DOI 10.1038/35019000
-
Moloney DJ, Panin VM, Johnston SH et al.: Fringe is a glycosyltransferase that modifes Notch. Nature 406(6794), 369-375 (2000). (Pubitemid 30625549)
-
(2000)
Nature
, vol.406
, Issue.6794
, pp. 369-375
-
-
Moloney, D.J.1
Panin, V.M.2
Johnston, S.H.3
Chen, J.4
Shao, L.5
Wilson, R.6
Wang, Y.7
Stanley, P.8
Irvine, K.D.9
Haltiwanger, R.S.10
Vogt, T.F.11
-
125
-
-
0030744231
-
A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway
-
Johnston SH, Rauskolb C, Wilson R, Prabhakaran B, Irvine KD, Vogt TF: A family of mammalian Fringe genes i mplicated in boundary determination and the Notch pathway. Development 124(11), 2245-2254 (1997). (Pubitemid 27283245)
-
(1997)
Development
, vol.124
, Issue.11
, pp. 2245-2254
-
-
Johnston, S.H.1
Rauskolb, C.2
Wilson, R.3
Prabhakaran, B.4
Irvine, K.D.5
Vogt, T.F.6
-
126
-
-
0030707948
-
EWS/FLI1-induced manic fringe renders NIH 3T3 cells tumorigenic
-
May WA, Arvand A, Thompson AD, Braun BS, Wright M, Denny CT: EWS/FLI1-induced Manic Fringe renders NIH 3T3 cells tumorigenic. Nat. Genet. 17(4), 495-497 (1997). (Pubitemid 27518406)
-
(1997)
Nature Genetics
, vol.17
, Issue.4
, pp. 495-497
-
-
May, W.A.1
Arvand, A.2
Thompson, A.D.3
Braun, B.S.4
Wright, M.5
Denny, C.T.6
-
127
-
-
18244402404
-
Pervasive regulation of Drosophila Notch target genes by GY-box-, Brd-box-, and K-box-class microRNAs
-
DOI 10.1101/gad.1291905
-
Lai EC, Tam B, Rubin GM: Pervasive regulation of Drosophila Notch target genes by GY-box-, Brd-box-, and K-box-class microRNAs. Genes Dev. 19(9), 1067-1080 (2005). (Pubitemid 40632452)
-
(2005)
Genes and Development
, vol.19
, Issue.9
, pp. 1067-1080
-
-
Lai, E.C.1
Tam, B.2
Rubin, G.M.3
-
128
-
-
72849108572
-
The neuronal microRNA mirR-326 acts in a feedback loop with Notch and has therapeutic potential against brain tumours
-
Kefas B, Comeau L, Floyd D et al.: The neuronal microRNA mirR-326 acts in a feedback loop with Notch and has therapeutic potential against brain tumours. Neurobiol. Dis. 29(48), 15161-15168 (2010).
-
(2010)
Neurobiol. Dis.
, vol.29
, Issue.48
, pp. 15161-15168
-
-
Kefas, B.1
Comeau, L.2
Floyd, D.3
-
129
-
-
55749093822
-
The microRNA miR-8 is a conserved negative regulator of Wnt signaling
-
Kennell JA, Gerin I, Macdougald OA, Cadigan KM: The microRNA miR-8 is a conserved negative regulator of Wnt signaling. Proc Natl Acad. Sci. USA 105(40), 15417-15422 (2008).
-
(2008)
Proc Natl Acad. Sci. USA
, vol.105
, Issue.40
, pp. 15417-15422
-
-
Kennell, J.A.1
Gerin, I.2
MacDougald, O.A.3
Cadigan, K.M.4
-
130
-
-
57449109120
-
Regulation of zebrafsh fn regeneration by microRNAs
-
Thatcher EJ, Paydar I, Anderson KK, Patton JG: Regulation of zebrafsh fn regeneration by microRNAs. Proc Natl Acad. Sci. USA 105(47), 18384-18389 (2008).
-
(2008)
Proc Natl Acad. Sci. USA
, vol.105
, Issue.47
, pp. 18384-18389
-
-
Thatcher, E.J.1
Paydar, I.2
Anderson, K.K.3
Patton, J.G.4
-
131
-
-
35348914716
-
Target protectors reveal dampening and balancing of nodal agonist and antagonist by miR-430
-
DOI 10.1126/science.1147535
-
Choi WY, Giraldez AJ, Schier AF: Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430. Science 318(5848), 271-274 (2007). (Pubitemid 47574854)
-
(2007)
Science
, vol.318
, Issue.5848
, pp. 271-274
-
-
Choi, W.-Y.1
Giraldez, A.J.2
Schier, A.F.3
-
132
-
-
34548607471
-
MicroRNA control of Nodal signalling
-
DOI 10.1038/nature06100, PII NATURE06100
-
Martello G, Zacchigna L, Inui M et al.: MicroRNA control of nodal signalling. Nature 449(7159), 183-188 (2007). (Pubitemid 47402367)
-
(2007)
Nature
, vol.449
, Issue.7159
, pp. 183-188
-
-
Martello, G.1
Zacchigna, L.2
Inui, M.3
Montagner, M.4
Adorno, M.5
Mamidi, A.6
Morsut, L.7
Soligo, S.8
Tran, U.9
Dupont, S.10
Cordenonsi, M.11
Wessely, O.12
Piccolo, S.13
-
133
-
-
68949169031
-
MicroRNA-23b cluster microRNAs regulate transforming growth factor-β/bone morphogenetic protein signaling and liver stem cell differentiation by targeting Smads
-
Rogler CE, Levoci L, Ader T et al.: MicroRNA-23b cluster microRNAs regulate transforming growth factor-β/bone morphogenetic protein signaling and liver stem cell differentiation by targeting Smads. Hepatology 50(2), 575-584 (2009).
-
(2009)
Hepatology
, vol.50
, Issue.2
, pp. 575-584
-
-
Rogler, C.E.1
Levoci, L.2
Ader, T.3
-
134
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
DOI 10.1016/j.cell.2005.01.014
-
Johnson SM, Grosshans H, Shingara J et al.: RAS is regulated by the let-7 microRNA family. Cell 120(5), 635-647 (2005). (Pubitemid 40343076)
-
(2005)
Cell
, vol.120
, Issue.5
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
Byrom, M.4
Jarvis, R.5
Cheng, A.6
Labourier, E.7
Reinert, K.L.8
Brown, D.9
Slack, F.J.10
-
135
-
-
48749130187
-
MiR-126 regulates angiogenic signaling and vascular integrity
-
Fish JE, Santoro MM, Morton SU et al.: miR-126 regulates angiogenic signaling and vascular integrity. Dev. Cell 15(2), 272-284 (2008).
-
(2008)
Dev. Cell
, vol.15
, Issue.2
, pp. 272-284
-
-
Fish, J.E.1
Santoro, M.M.2
Morton, S.U.3
-
136
-
-
57749168828
-
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fbroblasts
-
Thum T, Gross C, Fiedler J et al.: MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fbroblasts. Nature 456(7224), 980-984 (2008).
-
(2008)
Nature
, vol.456
, Issue.7224
, pp. 980-984
-
-
Thum, T.1
Gross, C.2
Fiedler, J.3
-
137
-
-
60849106298
-
Attribution of vascular phenotypes of the murine Egf7 locus to the microRNA miR-126
-
Kuhnert F, Mancuso MR, Hampton J et al.: Attribution of vascular phenotypes of the murine Egf7 locus to the microRNA miR-126. Development 135(24), 3989-3993 (2008).
-
(2008)
Development
, vol.135
, Issue.24
, pp. 3989-3993
-
-
Kuhnert, F.1
Mancuso, M.R.2
Hampton, J.3
-
138
-
-
34547524771
-
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
-
DOI 10.1053/j.gastro.2007.05.022, PII S0016508507010025
-
Meng F, Henson R, Wehb e-Janek H, Ghoshal K, Jacob ST, Patel T: MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133(2), 647-658 (2007). (Pubitemid 47187346)
-
(2007)
Gastroenterology
, vol.133
, Issue.2
, pp. 647-658
-
-
Meng, F.1
Henson, R.2
Wehbe-Janek, H.3
Ghoshal, K.4
Jacob, S.T.5
Patel, T.6
-
139
-
-
66149173789
-
The PTEN-regulating microRNA miR-26a is amplifed in high-grade glioma and facilitates gliomagenesis in vivo
-
Huse JT, Brennan C, Hambardzumyan D et al.: The PTEN-regulating microRNA miR-26a is amplifed in high-grade glioma and facilitates gliomagenesis in vivo. Genes Dev. 23(11), 1327-1337 (2009).
-
(2009)
Genes Dev.
, vol.23
, Issue.11
, pp. 1327-1337
-
-
Huse, J.T.1
Brennan, C.2
Hambardzumyan, D.3
-
140
-
-
67650085171
-
TGF-β activates AKT kinase through a microRNA-dependent amplifying circuit targeting PTEN
-
Kato M, Putta S, Wang M et al.: TGF-β activates AKT kinase through a microRNA-dependent amplifying circuit targeting PTEN. Nat. Cell Biol. 11(7), 881-889 (2009).
-
(2009)
Nat. Cell Biol.
, vol.11
, Issue.7
, pp. 881-889
-
-
Kato, M.1
Putta, S.2
Wang, M.3
-
141
-
-
58549114916
-
MiR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells
-
Li N, Fu H, Tie Y et al.: miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells. Cancer Lett. 275(1), 44-53 (2009).
-
(2009)
Cancer Lett.
, vol.275
, Issue.1
, pp. 44-53
-
-
Li, N.1
Fu, H.2
Tie, Y.3
-
142
-
-
63449135077
-
MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma
-
Garzia L, Andolfo I, Cusanelli E et al.: MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma. PLoS One 4(3), E4998 (2009).
-
(2009)
PLoS One
, vol.4
, Issue.3
-
-
Garzia, L.1
Andolfo, I.2
Cusanelli, E.3
-
143
-
-
59649112848
-
Regulation of angiogenesis by oxygen and metabolism
-
Fraisl P, Mazzone M, Schmidt T, Carmeliet P: Regulation of angiogenesis by oxygen and metabolism. Dev. Cell 16(2), 167-179 (2009).
-
(2009)
Dev. Cell
, vol.16
, Issue.2
, pp. 167-179
-
-
Fraisl, P.1
Mazzone, M.2
Schmidt, T.3
Carmeliet, P.4
-
145
-
-
0034671256
-
Relationship of hypoxia-inducible factor (HIF)-1α and HIF-2α expression to vascular endothelial growth factor induction and hypoxia survival in human breast cancer cell lines
-
Blancher C Moore JW, Talks KL, Houlbrook S, Harris AL: Relationship of hypoxia-inducible factor (HIF)-1α and HIF-2α expression to vascular endothelial growth factor induction and hypoxia survival in human breast cancer cell lines. Cancer Res. 60(24), 7106-7113 (2000). (Pubitemid 32059191)
-
(2000)
Cancer Research
, vol.60
, Issue.24
, pp. 7106-7113
-
-
Blancher, C.1
Moore, J.W.2
Talks, K.L.3
Houlbrook, S.4
Harris, A.L.5
-
146
-
-
0029117223
-
Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 gliom a cells
-
Ikeda E, Achen MG, Breier G, Risau W: Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 gliom a cells. J. Biol. Chem. 270(34), 19761-19766 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.34
, pp. 19761-19766
-
-
Ikeda, E.1
Achen, M.G.2
Breier, G.3
Risau, W.4
-
147
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
DOI 10.1016/j.cell.2005.02.034, PII S0092867405002370
-
Orimo A, Gupta PB, Sgroi DC et al.: Stromal fbroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121(3), 335-348 (2005). (Pubitemid 40692295)
-
(2005)
Cell
, vol.121
, Issue.3
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.B.2
Sgroi, D.C.3
Arenzana-Seisdedos, F.4
Delaunay, T.5
Naeem, R.6
Carey, V.J.7
Richardson, A.L.8
Weinberg, R.A.9
-
148
-
-
7944223098
-
Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis
-
DOI 10.1016/j.ccr.2004.09.028, PII S1535610804003009
-
Sparmann A, Bar-Sagi D: Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis. Cancer Cell 6(5), 447-458 (2004). (Pubitemid 39469981)
-
(2004)
Cancer Cell
, vol.6
, Issue.5
, pp. 447-458
-
-
Sparmann, A.1
Bar-Sagi, D.2
-
149
-
-
59649085554
-
Angiogenesis: A team effort coordinated by Notch
-
Phng LK, Gerhardt H: Angiogenesis: a team effort coordinated by Notch. Dev. Cell 16(2), 196-208 (2009).
-
(2009)
Dev. Cell
, vol.16
, Issue.2
, pp. 196-208
-
-
Phng, L.K.1
Gerhardt, H.2
-
150
-
-
8844262579
-
Periodic Delta-like 4 expression in developing retinal arteries
-
DOI 10.1016/j.modgep.2004.05.004, PII S1567133X04000821
-
Claxton S, Fruttiger M: Periodic Delta-like 4 expression in developing retinal arteries. Gene Expr. Patterns 5(1), 123-127 (2004). (Pubitemid 39529808)
-
(2004)
Gene Expression Patterns
, vol.5
, Issue.1
, pp. 123-127
-
-
Claxton, S.1
Fruttiger, M.2
-
151
-
-
33845642740
-
Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate
-
DOI 10.1016/j.yexcr.2006.09.009, PII S0014482706003880
-
Diez H, Fischer A, Winkler A et al.: Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate. Exp. Cell Res. 313(1), 1-9 (2007). (Pubitemid 44958449)
-
(2007)
Experimental Cell Research
, vol.313
, Issue.1
, pp. 1-9
-
-
Diez, H.1
Fischer, A.2
Winkler, A.3
Hu, C.-J.4
Hatzopoulos, A.K.5
Breier, G.6
Gessler, M.7
-
152
-
-
33745099879
-
The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development
-
DOI 10.1016/j.ydbio.2006.03.035, PII S0012160606002375
-
Seo S, Fujita H, Nakano A, Kang M, Duarte A, Kume T: The forkhead transcription factors, FoxC1 and FoxC2, are required for arterial specifcation and lymphatic sprouting during vascular development. Dev. Biol. 294(2), 458-470 (2006). (Pubitemid 43884821)
-
(2006)
Developmental Biology
, vol.294
, Issue.2
, pp. 458-470
-
-
Seo, S.1
Fujita, H.2
Nakano, A.3
Kang, M.4
Duarte, A.5
Kume, T.6
-
153
-
-
0037216703
-
Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: Implications for modulating arteriogenesis and angiogenesis
-
DOI 10.1128/MCB.23.1.14-25.2003
-
Liu ZJ, Shirakawa T, Li Y et al.: Regulation of Notch1 and Dll4 b y vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis. Mol. Cell Biol. 23(1), 14-25 (2003). (Pubitemid 36008497)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.1
, pp. 14-25
-
-
Liu, Z.-J.1
Shirakawa, T.2
Li, Y.3
Soma, A.4
Oka, M.5
Dotto, G.P.6
Fairman, R.M.7
Velazquez, O.C.8
Herlyn, M.9
-
154
-
-
31544448010
-
Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function
-
DOI 10.1182/blood-2005-03-1000
-
Williams CK, Li JL, Murga M, Harris AL, Tosato G: Up-regulation of the Notch ligand Delta-like 4 inhibits VEGF-induced endothelial cell function. Blood 107(3), 931-939 (2006). (Pubitemid 43156289)
-
(2006)
Blood
, vol.107
, Issue.3
, pp. 931-939
-
-
Williams, C.K.1
Li, J.-L.2
Murga, M.3
Harris, A.L.4
Tosato, G.5
-
155
-
-
48749117994
-
Foxc transcription factors directly regulate Dll4 and HEY2 expression by interacting with the VEGF-Notch signaling pathways in endothelial cells
-
Hayashi H, Kume T: Foxc transcription factors directly regulate Dll4 and HEY2 expression by interacting with the VEGF-Notch signaling pathways in endothelial cells. PLoS One 3(6), E2401 (2008).
-
(2008)
PLoS One
, vol.3
, Issue.6
-
-
Hayashi, H.1
Kume, T.2
-
156
-
-
0036433637
-
Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/KDR expression
-
DOI 10.1006/mvre.2002.2443
-
Taylor KL, Henderson AM, Hughes CC: Notch activation during e ndothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/KDR expression. Microvasc Res. 64(3), 372-383 (2002). (Pubitemid 35370739)
-
(2002)
Microvascular Research
, vol.64
, Issue.3
, pp. 372-383
-
-
Taylor, K.L.1
Henderson, A.M.2
Hughes, C.C.W.3
-
157
-
-
1642523576
-
Notch4 Inhibits Endothelial Apoptosis via RBP-Jκ-dependent and -independent Pathways
-
DOI 10.1074/jbc.M312102200
-
Mackenzie F, Duriez P, Wong F, Noseda M, Karsan A: Notch4 inhibits endothelial apoptosis via RBP-J-dependent and-independent pathways. J. Biol. Chem. 279(12), 11657-11663 (2004). (Pubitemid 38401668)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.12
, pp. 11657-11663
-
-
MacKenzie, F.1
Duriez, P.2
Wong, F.3
Noseda, M.4
Karsan, A.5
-
158
-
-
36048978608
-
Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression
-
DOI 10.1172/JCI24311
-
Shawber CJ, Funahashi Y, Francisco E et al.: Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression. J. Clin. Invest. 117(11), 3369-3382 (2007). (Pubitemid 350096993)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.11
, pp. 3369-3382
-
-
Shawber, C.J.1
Funahashi, Y.2
Francisco, E.3
Vorontchikhina, M.4
Kitamura, Y.5
Stowell, S.A.6
Borisenko, V.7
Feirt, N.8
Podgrabinska, S.9
Shiraishi, K.10
Chawengsaksophak, K.11
Rossant, J.12
Accili, D.13
Skobe, M.14
Kitajewski, J.15
-
159
-
-
34948907354
-
Notch3 activation modulates cell growth behaviour and cross-talk to Wnt/TCF signalling pathway
-
DOI 10.1016/j.cellsig.2007.07.019, PII S0898656807002331
-
Wang T, Holt CM, Xu C et al.: Notch3 activation modulates cell growth behaviour and cross-talk to Wnt/TCF signalling pathway. Cell Signal 19(12), 2458-2467 (2007). (Pubitemid 47531927)
-
(2007)
Cellular Signalling
, vol.19
, Issue.12
, pp. 2458-2467
-
-
Wang, T.1
Holt, C.M.2
Xu, C.3
Ridley, C.4
P O Jones, R.5
Baron, M.6
Trump, D.7
-
160
-
-
77951197865
-
Convergence of Notch and β-catenin signaling induces arterial fate in vascular progenitors
-
Yamamizu K, Matsunaga T, Uosaki H et al.: Convergence of Notch and β-catenin signaling induces arterial fate in vascular progenitors. J. Cell Biol. 189(2), 325-338 (2010).
-
(2010)
J. Cell Biol.
, vol.189
, Issue.2
, pp. 325-338
-
-
Yamamizu, K.1
Matsunaga, T.2
Uosaki, H.3
-
161
-
-
77952634453
-
NADPH oxidase 1 modulates WNT and Not ch1 signaling to control the fate of proliferative progenitor cells in the colon
-
Coant N, Ben Mkaddem S, Pedruzzi E et al.: NADPH oxidase 1 modulates WNT and Not ch1 signaling to control the fate of proliferative progenitor cells in the colon. Mol. Cell Biol. 30(11), 2636-2650 (2010).
-
(2010)
Mol. Cell Biol.
, vol.30
, Issue.11
, pp. 2636-2650
-
-
Coant, N.1
Ben Mkaddem, S.2
Pedruzzi, E.3
-
162
-
-
77955977167
-
The Wnt/β-catenin pathway modulates vascular remodeling and specifcation by upregulating Dll4/Notch signaling
-
Corada M, Nyqvist D, Orsenigo F et al.: The Wnt/β-catenin pathway modulates vascular remodeling and specifcation by upregulating Dll4/Notch signaling. Dev. Cell 18(6), 938-949 (2010).
-
(2010)
Dev. Cell
, vol.18
, Issue.6
, pp. 938-949
-
-
Corada, M.1
Nyqvist, D.2
Orsenigo, F.3
-
163
-
-
33746765208
-
Notch ligand, Jag1, is evolutionarily conserved target of canonical Wnt signaling pathway in progenitor cells
-
Katoh M: Notch ligand, Jag1, is evolutionarily conserved target of canonical Wnt signaling pathway in progenitor cells. Int. J. Mol. Med. 17(4),
-
(2006)
Int. J. Mol. Med.
, vol.17
, Issue.4
, pp. 681-685
-
-
Katoh, M.1
-
164
-
-
46749123975
-
TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype
-
Sainson RC, Johnston DA, Chu HC et al.: TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype. Blood 111(10), 4997-5007 (2008).
-
(2008)
Blood
, vol.111
, Issue.10
, pp. 4997-5007
-
-
Sainson, R.C.1
Johnston, D.A.2
Chu, H.C.3
-
165
-
-
33747884849
-
Delta-4 expression on a stromal cell line is augmented by interleukin-6 via STAT3 activat ion
-
Suzuki M, Yamamoto M, Sugimoto A, Nakamura S, Motoda R, Orita K: Delta-4 expression on a stromal cell line is augmented by interleukin-6 via STAT3 activat ion. Exp. Hematol. 34(9), 1143-1150 (2006).
-
(2006)
Exp. Hematol.
, vol.34
, Issue.9
, pp. 1143-1150
-
-
Suzuki, M.1
Yamamoto, M.2
Sugimoto, A.3
Nakamura, S.4
Motoda, R.5
Orita, K.6
-
166
-
-
77955855682
-
The MAPK-dependent regulation of the Jagged/Notch gene expression by VEGF, bFGF or PPAR γ mediated angiogenesis in HUVEC
-
Kiec-Wilk B, Grzybowska-Galuszka J, Polus A, Pryjma J, Knapp A, Kristiansen K: The MAPK-dependent regulation of the Jagged/Notch gene expression by VEGF, bFGF or PPAR γ mediated angiogenesis in HUVEC. J. Physiol. Pharmacol. 61(2), 217-225 (2010).
-
(2010)
J. Physiol. Pharmacol.
, vol.61
, Issue.2
, pp. 217-225
-
-
Kiec-Wilk, B.1
Grzybowska-Galuszka, J.2
Polus, A.3
Pryjma, J.4
Knapp, A.5
Kristiansen, K.6
-
167
-
-
77953362501
-
Molecular mechanisms underlying tumor dormancy
-
Almog N: Molecular mechanisms underlying tumor dormancy. Cancer Lett. 294(2), 139-146 (2010).
-
(2010)
Cancer Lett.
, vol.294
, Issue.2
, pp. 139-146
-
-
Almog, N.1
-
168
-
-
70350736093
-
The angiogenic switch: Implications in the regulation of tumor dormancy
-
Moserle L, Amadori A, Indraccolo S: The angiogenic switch: implications in the regulation of tumor dormancy. Curr. Mol. Med. 9(8), 935-941 (2009).
-
(2009)
Curr. Mol. Med.
, vol.9
, Issue.8
, pp. 935-941
-
-
Moserle, L.1
Amadori, A.2
Indraccolo, S.3
-
169
-
-
35548936833
-
Models, mechanisms and clinical evidence for cancer dormancy
-
DOI 10.1038/nrc2256, PII NRC2256
-
Aguirre-Ghiso JA: Models, mechanisms and clinical evidence for cancer dormancy. Nat. Rev. Cancer 7(11), 834-846 (2007). (Pubitemid 350006258)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.11
, pp. 834-846
-
-
Aguirre-Ghiso, J.A.1
-
170
-
-
60549117358
-
Cross-talk between tumor and endothelial cells involvi ng the Notch3-Dll4 interaction marks escape from tumor dormancy
-
Indraccolo S, Minuzzo S, Masiero M et al.: Cross-talk between tumor and endothelial cells involvi ng the Notch3-Dll4 interaction marks escape from tumor dormancy. Cancer Res. 69(4), 1314-1323 (2009).
-
(2009)
Cancer Res.
, vol.69
, Issue.4
, pp. 1314-1323
-
-
Indraccolo, S.1
Minuzzo, S.2
Masiero, M.3
-
171
-
-
0036078659
-
Mouse Notch 3 expression in the pre- and postnatal brain: Relationship to the stroke and dementia syndrome CADASIL
-
DOI 10.1006/excr.2002.5544
-
Prakash N, Hansson E, Betsholtz C, Mitsiadis T, Lendahl U: Mouse Notch 3 expression in th e pre-and postnatal brain: relationship to the stroke and dementia syndrome CADASIL. Exp. Cell Res. 278(1), 31-44 (2002). (Pubitemid 34775443)
-
(2002)
Experimental Cell Research
, vol.278
, Issue.1
, pp. 31-44
-
-
Prakash, N.1
Hansson, E.2
Betsholtz, C.3
Mitsiadis, T.4
Lendahl, U.5
-
172
-
-
43049176532
-
An overview of Notch3 function in vascular smooth muscle cells
-
DOI 10.1016/j.pbiomolbio.2007.07.006, PII S0079610707000508
-
Wang T, Baron M, Trump D: An overview of Notch3 function in vascular smooth muscle cells. Prog. Biophys. Mol. Biol. 96(1-3), 499-509 (2008). (Pubitemid 351635621)
-
(2008)
Progress in Biophysics and Molecular Biology
, vol.96
, Issue.1-3
, pp. 499-509
-
-
Wang, T.1
Baron, M.2
Trump, D.3
-
173
-
-
0036493984
-
Relation of hypoxia-inducible factor-2α (HIF-2α) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in human breast cancer
-
Leek RD, Talks KL, Pezzella F et al.: Relation of hypoxia-inducible factor-2 a (HIF-2 a) expression in tumor-infltrative macrophages t o tumor angiogenesis and the oxidative thymidine phosphorylase pathway in human breast cancer. Cancer Res. 62(5), 1326-1329 (2002). (Pubitemid 34407787)
-
(2002)
Cancer Research
, vol.62
, Issue.5
, pp. 1326-1329
-
-
Leek, R.D.1
Talks, K.L.2
Pezzella, F.3
Turley, H.4
Campo, L.5
Brown, N.S.6
Bicknell, R.7
Taylor, M.8
Gatter, K.C.9
Harris, A.L.10
-
174
-
-
0036202693
-
Angiogenic co-operation of VEGF and stromall cell TP in endometrial carcinomas
-
DOI 10.1002/path.1060
-
Sivridis E, Giatromanolaki A, Anastasiadis P et al.: Angiogenic co-operation of VEGF and stromal cell TP in endometrial carcinomas. J. Pathol. 196(4), 416-422 (2002). (Pubitemid 34262853)
-
(2002)
Journal of Pathology
, vol.196
, Issue.4
, pp. 416-422
-
-
Sivridis, E.1
Giatromanolaki, A.2
Anastasiadis, P.3
Georgiou, L.4
Gatter, K.C.5
Harris, A.L.6
Bicknell, R.7
Koukourakis, M.I.8
-
175
-
-
0036187615
-
The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
-
DOI 10.1002/path.1027
-
Bingle L, Brown NJ, Lewis CE: The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J. Pathol. 196(3), 254-265 (2002). (Pubitemid 34189413)
-
(2002)
Journal of Pathology
, vol.196
, Issue.3
, pp. 254-265
-
-
Bingle, L.1
Brown, N.J.2
Lewis, C.E.3
-
176
-
-
34248141100
-
A cytokine-mediated link between innate immunity, inflammation, and cancer
-
DOI 10.1172/JCI31537
-
Lin WW, Karin M: A cytokine-mediated link between innate immunity, infammation, and cancer. J. Clin. Invest. 117(5), 1175-1183 (2007). (Pubitemid 46718402)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.5
, pp. 1175-1183
-
-
Lin, W.-W.1
Karin, M.2
-
177
-
-
4944244259
-
Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues
-
DOI 10.1182/blood-2004-03-1109
-
Murdoch C, Giannoudis A, Lewis CE: Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues. Blood 104(8), 2224-2234 (2004). (Pubitemid 39331817)
-
(2004)
Blood
, vol.104
, Issue.8
, pp. 2224-2234
-
-
Murdoch, C.1
Giannoudis, A.2
Lewis, C.E.3
-
178
-
-
0033067163
-
Necrosis correlates with high vascular density and focal macrophage infltration in invasive carcinoma of the breast
-
Leek RD, Landers RJ, Harris AL, Lewis CE: Necrosis correlates with high vascular density and focal macrophage infltration in invasive carcinoma of the breast. Br. J. Cancer 79(5-6), 99 1-995 (1999).
-
(1999)
Br. J. Cancer
, vol.79
, Issue.5-6
, pp. 991-995
-
-
Leek, R.D.1
Landers, R.J.2
Harris, A.L.3
Lewis, C.E.4
-
179
-
-
0030944928
-
Quantitative assessment of the leukocyte infiltrate in ovarian cancer and its relationship to the expression of C-C chemokines
-
Negus RP, Stamp GW, Hadley J, Balkwill FR: Quantitative assessment of the leukocyte infltrate in ovarian cancer and its relationship to the expression of C-C chemokines. Am. J. Pathol. 150(5), 1723-1734 (1997). (Pubitemid 27193819)
-
(1997)
American Journal of Pathology
, vol.150
, Issue.5
, pp. 1723-1734
-
-
Negus, R.P.M.1
Stamp, G.W.H.2
Hadley, J.3
Balkwill, F.R.4
-
180
-
-
6344250782
-
Correlation of histological localization of tumor-associated macrophages with clinicopathological features in endometrial cancer
-
Ohno S, Ohno Y, Suzuki N et al.: Correlation of histological localization of tumor-associated macrophages with clinicopathological features in endometrial cancer. Anticancer Res. 24(5C), 3335-3342 (2004). (Pubitemid 39390949)
-
(2004)
Anticancer Research
, vol.24
, Issue.5
, pp. 3335-3342
-
-
Ohno, S.1
Ohno, Y.2
Suzuki, N.3
Kamei, T.4
Koike, K.5
Inagawa, H.6
Kohchi, C.7
Soma, G.-I.8
Inoue, M.9
-
181
-
-
31544441610
-
Distinct role of macrophages in different tumor microenvironments
-
DOI 10.1158/0008-5472.CAN-05-4005
-
Lewis CE, Pollard JW: Distinct role of macrophages in different tumor microenvironments. Cancer Res. 66(2), 605-612 (2006). (Pubitemid 43165918)
-
(2006)
Cancer Research
, vol.66
, Issue.2
, pp. 605-612
-
-
Lewis, C.E.1
Pollard, J.W.2
-
182
-
-
34250313956
-
Delta-like 4 induces Notch signaling in macrophages: Implications for inflammation
-
DOI 10.1161/CIRCULATIONAHA.106.675462
-
Fung E, Tang SM, Canner JP et al.: Delta-like 4 induces notch signaling in macrophages: implications for infammation. Circulation 115(23), 2948-2956 (2007). (Pubitemid 46912098)
-
(2007)
Circulation
, vol.115
, Issue.23
, pp. 2948-2956
-
-
Fung, E.1
Tang, S.-M.T.2
Canner, J.P.3
Morishige, K.4
Arboleda-Velasquez, J.F.5
Cardoso, A.A.6
Carlesso, N.7
Aster, J.C.8
Aikawa, M.9
-
183
-
-
67949097489
-
Exosomes-vesicular carriers for intercellular communication
-
Simons M, Raposo G: Exosomes-vesicular carriers for intercellular communication. Curr. Opin. Cell Biol. 21(4), 575-581 (2009).
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, Issue.4
, pp. 575-581
-
-
Simons, M.1
Raposo, G.2
-
184
-
-
70350681050
-
Paracrine induction of endothelium by tumor exosomes
-
Hood JL, Pan H, Lanza GM, Wickline SA: Paracrine induction of endothelium by tumor exosomes. Lab. Invest. 89(11), 1317-1328 (2009).
-
(2009)
Lab. Invest.
, vol.89
, Issue.11
, pp. 1317-1328
-
-
Hood, J.L.1
Pan, H.2
Lanza, G.M.3
Wickline, S.A.4
-
185
-
-
77957708340
-
New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes
-
Sheldon H, Heikamp E, Turley H et al.: New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes. Blood 116(13), 2385-2394 (2010).
-
(2010)
Blood
, vol.116
, Issue.13
, pp. 2385-2394
-
-
Sheldon, H.1
Heikamp, E.2
Turley, H.3
-
186
-
-
20444495706
-
Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis
-
DOI 10.1096/fj.04-3172fje
-
Sainson RC, Aoto J, Nakatsu MN et al.: Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis. FASEB J. 19(8), 1027-1029 (2005). (Pubitemid 40827740)
-
(2005)
FASEB Journal
, vol.19
, Issue.8
, pp. 1027-1029
-
-
Sainson, R.C.A.1
Aoto, J.2
Nakatsu, M.N.3
Holderfield, M.4
Conn, E.5
Koller, E.6
Hughes, C.C.W.7
-
187
-
-
0037108367
-
The Notch ligand jagged-1 is able to induce maturation of monocyte-derived human dendritic cells
-
Weijzen S, Velders MP, Elmishad AG et al.: The Notch ligand Jagged-1 is able to induce maturation of monocyte-derived human dendritic cells. J. Immunol. 169(8), 4273-4278 (2002). (Pubitemid 35178199)
-
(2002)
Journal of Immunology
, vol.169
, Issue.8
, pp. 4273-4278
-
-
Weijzen, S.1
Velders, M.P.2
Elmishad, A.G.3
Bacon, P.E.4
Panella, J.R.5
Nickoloff, B.J.6
Miele, L.7
Kast, W.M.8
-
188
-
-
33847046849
-
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
-
DOI 10.1038/nature05571, PII NATURE05571
-
Hellstrom M, Phng LK, Hofmann JJ et al.: Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature 445(7129), 776-780 (2007). (Pubitemid 46279716)
-
(2007)
Nature
, vol.445
, Issue.7129
, pp. 776-780
-
-
Hellstrom, M.1
Phng, L.-K.2
Hofmann, J.J.3
Wallgard, E.4
Coultas, L.5
Lindblom, P.6
Alva, J.7
Nilsson, A.-K.8
Karlsson, L.9
Gaiano, N.10
Yoon, K.11
Rossant, J.12
Iruela-Arispe, M.L.13
Kalen, M.14
Gerhardt, H.15
Betsholtz, C.16
-
189
-
-
35548936513
-
Biological function of mutant forms of JAGGED1 proteins in Alagille syndrome: Inhibitory effect on Notch signaling
-
Boyer-Di Ponio J, Wr ight-Crosnier C, Groyer-Picard MT et al.: Biological function of mutant forms of JAGGED1 proteins in Alagille syndrome: inhibitory effect on Notch signaling. Hum. Mol. Genet. 16(22), 2683-2692 (2007).
-
(2007)
Hum. Mol. Genet.
, vol.16
, Issue.22
, pp. 2683-2692
-
-
Boyer-Di Ponio, J.1
Wr Ight-Crosnier, C.2
Groyer-Picard, M.T.3
-
190
-
-
1342329716
-
Autocrine pathways of the vascular endothelial growth factor (VEGF) in glioblastoma multiforme: Clinical relevance of radiation-induced increase of VEGF levels
-
DOI 10.1023/B:NEON.0000013495.08168.8f
-
Ste iner HH, Karcher S, Mueller MM, Nalbantis E, Kunze S, Herold-Mende C: Autocrine pathways of the vascular endothelial growth factor (VEGF) in glioblastoma multiforme: clinical relevance of radiation-induced increase of VEGF levels. J. Neurooncol. 66(1-2), 129-138 (2004). (Pubitemid 38258367)
-
(2004)
Journal of Neuro-Oncology
, vol.66
, Issue.1-2
, pp. 129-138
-
-
Steiner, H.-H.1
Karcher, S.2
Mueller, M.M.3
Nalbantis, E.4
Kunze, S.5
Herold-Mende, C.6
-
191
-
-
0034667464
-
Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth facto r expression in human glioblastoma cells via a pathway involving phosphatidylinositol 3́-kinase and distinct from that induced by hypoxia
-
Maity A, Pore N, Lee J, Solomon D, O'Rourke DM: Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth facto r expression in human glioblastoma cells via a pathway involving phosphatidylinositol 3́-kinase and distinct from that induced by hypoxia. Cancer Res. 60(20), 5879-5886 (2000).
-
(2000)
Cancer Res.
, vol.60
, Issue.20
, pp. 5879-5886
-
-
Maity, A.1
Pore, N.2
Lee, J.3
Solomon, D.4
O'Rourke, D.M.5
-
192
-
-
0027992961
-
Quantitative immunohistological analysis of the microvasculature in untreated human glioblastoma multiforme. Computer-assisted image analysis of whole-tumor sections
-
Wesseling P, Van Der Laak JA, De Leeuw H, Ruiter DJ, Burger PC: Quantitative immunohistological analysis of the microvasculature in untreated human glioblastoma multiforme. Computer-assisted image analysis of whole-tumor sections. J. Neurosurg. 81(6), 902-909 (1994). (Pubitemid 24373471)
-
(1994)
Journal of Neurosurgery
, vol.81
, Issue.6
, pp. 902-909
-
-
Wesseling, P.1
Van Der Laak, J.A.W.M.2
De Leeuw, H.3
Ruiter, D.J.4
Burger, P.C.5
-
193
-
-
0035758208
-
Peritumoral angiogenesis around primary and metastatic brain neoplasms
-
Nowacki P, Kojder I: Peritumoral angiogenesis around primary and metastatic brain neoplasms. Morphometric analysis. Folia Neuropathol. 39(2), 95-102 (2001).
-
(2001)
Morphometric Analysis. Folia Neuropathol.
, vol.39
, Issue.2
, pp. 95-102
-
-
Nowacki, P.1
Kojder, I.2
-
194
-
-
78650153633
-
Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells
-
Ricci-Vitiani L, Pallini R, Biffoni M et al.: Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells. Nature 468, 824-828 (2010).
-
(2010)
Nature
, vol.468
, pp. 824-828
-
-
Ricci-Vitiani, L.1
Pallini, R.2
Biffoni, M.3
-
195
-
-
78650098659
-
Glioblastoma stem-like cells give rise to tumour endothelium
-
Wang R, Chadalavada K, Wilshire J et al.: Glioblastoma stem-like cells give rise to tumour endothelium. Nature 468, 829-833, (2010).
-
(2010)
Nature
, vol.468
, pp. 829-833
-
-
Wang, R.1
Chadalavada, K.2
Wilshire, J.3
-
196
-
-
77956803700
-
The perivascular niche microenvironment in brain tumor progression
-
Charles N, Holland EC: The perivascular niche microenvironment in brain tumor progression. Cell Cycle 9(15), 3012-3021 (2010).
-
(2010)
Cell Cycle
, vol.9
, Issue.15
, pp. 3012-3021
-
-
Charles, N.1
Holland, E.C.2
-
197
-
-
33847009903
-
Endothelial signalling by the Notch ligand Delta-like 4 restricts angiogenesis
-
DOI 10.1242/dev.003244
-
Leslie JD, Ariza-Mcnaughton L, Bermange AL, Mcadow R, Johnson SL, Lewis J: Endothelial signalling by the Notch ligand Delta-like 4 restricts angioge nesis. Development 134(5), 839-844 (2007). (Pubitemid 46795675)
-
(2007)
Development
, vol.134
, Issue.5
, pp. 839-844
-
-
Leslie, J.D.1
Ariza-McNaughton, L.2
Bermange, A.L.3
McAdow, R.4
Johnson, S.L.5
Lewis, J.6
-
198
-
-
34247539127
-
The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growth
-
DOI 10.1038/nrc2130, PII NRC2130
-
Thurston G, Noguera-Troise I, Yancopoulos GD: The Delta paradox: Dll4 blockade leads to more tumour vessels but less tumour growth. Nat. Rev. Cancer 7(5), 327-331 (2007). (Pubitemid 46652486)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.5
, pp. 327-331
-
-
Thurston, G.1
Noguera-Troise, I.2
Yancopoulos, G.D.3
-
199
-
-
34548535783
-
Anti-Dll4 therapy: Can we block tumour growth by increasing angiogenesis?
-
DOI 10.1016/j.molmed.2007.07.002, PII S1471491407001487
-
Sainson RC, Harris AL: Anti-Dll4 therapy: can we block tumour growth by increasing angiogenesis? Trends Mol. Med. 13(9), 389-395 (2007). (Pubitemid 47385383)
-
(2007)
Trends in Molecular Medicine
, vol.13
, Issue.9
, pp. 389-395
-
-
Sainson, R.C.A.1
Harris, A.L.2
-
200
-
-
30944446883
-
Lessons from phase III clinical trials on anti-VEGF therapy for cancer
-
DOI 10.1038/ncponc0403, PII N0403
-
Jain RK, Duda DG, Clark JW, Loeffer JS: Lessons from Phase III clinical trials on anti-VEGF therapy for cancer. Nat. Clin. Pract. Oncol. 3(1), 24-40 (2006). (Pubitemid 43108832)
-
(2006)
Nature Clinical Practice Oncology
, vol.3
, Issue.1
, pp. 24-40
-
-
Jain, R.K.1
Duda, D.G.2
Clark, J.W.3
Loeffler, J.S.4
-
201
-
-
30744449235
-
Angiogenesis as a therapeutic target
-
DOI 10.1038/nature04483, PII NATURE04483
-
Ferrara N, Kerbel RS: Angiogenesis as a therapeutic target. Nature 438(7070), 967-974 (2005). (Pubitemid 43093963)
-
(2005)
Nature
, vol.438
, Issue.7070
, pp. 967-974
-
-
Ferrara, N.1
Kerbel, R.S.2
-
202
-
-
33947214529
-
Notch signaling, G-secretase inhibitors, and cancer therapy
-
Shih IM, Wang TL: Notch signaling, g-secretase inhibitors, and cancer therapy Cancer Res. 67(5), 1879-1882 (2007).
-
(2007)
Cancer Res.
, vol.67
, Issue.5
, pp. 1879-1882
-
-
Shih, I.M.1
Wang, T.L.2
-
203
-
-
77953368267
-
Evaluation of selective g-secretase inhibitor PF-03084014 for its antitumor effcacy and gastrointestinal safety to guide optimal clinical trial design
-
Wei P, Walls M, Qiu M et al.: Evaluation of selective g-secretase inhibitor PF-03084014 for its antitumor effcacy and gastrointestinal safety to guide optimal clinical trial design. Mol. Cancer Ther. 9(6), 1618-1628 (2010).
-
(2010)
Mol. Cancer Ther.
, vol.9
, Issue.6
, pp. 1618-1628
-
-
Wei, P.1
Walls, M.2
Qiu, M.3
-
204
-
-
7444228699
-
The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of Sonic Hedgehog-induced medulloblastomas
-
DOI 10.1158/0008-5472.CAN-04-1813
-
Hallahan AR, Pritchard JI, Hansen S et al.: The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas. Cancer Res. 64(21), 7794-7800 (2004). (Pubitemid 39446912)
-
(2004)
Cancer Research
, vol.64
, Issue.21
, pp. 7794-7800
-
-
Hallahan, A.R.1
Pritchard, J.I.2
Hansen, S.3
Benson, M.4
Stoeck, J.5
Hatton, B.A.6
Russell, T.L.7
Ellenbogen, R.G.8
Bernstein, I.D.9
Beachy, P.A.10
Olson, J.M.11
-
205
-
-
76749157186
-
Chronic Dll4 blockade induces vascular neoplasms
-
Yan M, Callahan CA, Beyer JC et al.: Chronic Dll4 blockade induces vascular neoplasms. Nature 463(7282), E6-E7 (2010).
-
(2010)
Nature
, vol.463
, Issue.7282
-
-
Yan, M.1
Callahan, C.A.2
Beyer, J.C.3
-
206
-
-
72449208456
-
Nonspecifcity of binding of γ-secretase modulators to the amyloid precursor protein
-
Beel AJ, Barrett P, Schnier PD et al.: Nonspecifcity of binding of γ-secretase modulators to the amyloid precursor protein. Biochemistry 48(50), 11837-11839 (2009).
-
(2009)
Biochemistry
, vol.48
, Issue.50
, pp. 11837-11839
-
-
Beel, A.J.1
Barrett, P.2
Schnier, P.D.3
-
207
-
-
77951139188
-
Therapeutic antibody targeting of individual Notch receptors
-
Wu Y, Cain-Hom C, Choy L et al.: Therapeutic antibody targeting of individual Notch receptors. Nature 464(7291), 1052-1057 (2010).
-
(2010)
Nature
, vol.464
, Issue.7291
, pp. 1052-1057
-
-
Wu, Y.1
Cain-Hom, C.2
Choy, L.3
-
208
-
-
77955174317
-
Therapeutic effcacy of a DNA vaccine targeting the endothelial tip cell antigen Delta-like ligand 4 in mammary carcinoma
-
Haller BK, Brave A, Wallgard E et al.: Therapeutic effcacy of a DNA vaccine targeting the endothelial tip cell antigen Delta-like ligand 4 in mammary carcinoma. Oncogene 29(30), 4276-4286 (2010).
-
(2010)
Oncogene
, vol.29
, Issue.30
, pp. 4276-4286
-
-
Haller, B.K.1
Brave, A.2
Wallgard, E.3
-
209
-
-
78649466892
-
Targeting Notch signaling pathway to overcome drug resistance for cancer therapy
-
Wang Z, Li Y, Ahmad A et al.: Targeting Notch signaling pathway to overcome drug resistance for cancer therapy. Biochim. Biophys. Acta 1806(2), 258-267 (2010).
-
(2010)
Biochim. Biophys. Acta
, vol.1806
, Issue.2
, pp. 258-267
-
-
Wang, Z.1
Li, Y.2
Ahmad, A.3
-
210
-
-
77949457142
-
RNAi-mediated knockdown of Notch-1 leads to cell growth inhibition and enhanced chemosensitivity in human breast cancer
-
Zang S, Chen F, Dai J et al.: RNAi-mediated knockdown of Notch-1 leads to cell growth inhibition and enhanced chemosensitivity in human breast cancer. Oncol. Rep. 23(4), 893-899 (2010).
-
(2010)
Oncol. Rep.
, vol.23
, Issue.4
, pp. 893-899
-
-
Zang, S.1
Chen, F.2
Dai, J.3
-
211
-
-
77950292495
-
Downregulation of Notch pathway by a γ-secretase inhibitor attenuates AKT/mammalian target of rapamy cin signaling and glucose uptake in an ERBB2 transgenic breast cancer model
-
Efferson CL, Winkelmann CT, Ware C et al.: Downregulation of Notch pathway by a γ-secretase inhibitor attenuates AKT/mammalian target of rapamy cin signaling and glucose uptake in an ERBB2 transgenic breast cancer model. Cancer Res. 70(6), 2476-2484 (2010).
-
(2010)
Cancer Res.
, vol.70
, Issue.6
, pp. 2476-2484
-
-
Efferson, C.L.1
Winkelmann, C.T.2
Ware, C.3
-
212
-
-
77949395629
-
Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors
-
Aste-Amezaga M, Zhang N, Lineberger JE et al.: Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors. PLoS One 5(2), E9094 (2010).
-
(2010)
PLoS One
, vol.5
, Issue.2
-
-
Aste-Amezaga, M.1
Zhang, N.2
Lineberger, J.E.3
-
213
-
-
0031834239
-
A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
-
Benjamin LE, Hemo I, Keshet E: A plasticity window for blood vessel remodelling is defned by pericyte cov erage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 125(9), 1591-1598 (1998). (Pubitemid 28256727)
-
(1998)
Development
, vol.125
, Issue.9
, pp. 1591-1598
-
-
Benjamin, L.E.1
Hemo, I.2
Keshet, E.3
-
214
-
-
1442290142
-
Combined inhibition of VEGF and PDGF s ignaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms
-
Erber R, Thurnher A, Katsen AD et al.: Combined inhibition of VEGF and PDGF s ignaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms. FASEB J. 18(2), 338-340 (2004).
-
(2004)
FASEB J.
, vol.18
, Issue.2
, pp. 338-340
-
-
Erber, R.1
Thurnher, A.2
Katsen, A.D.3
-
215
-
-
68049140803
-
Overexpression of platelet-derived growth factor-BB increases tumor pericyte content via stromal-derived factor-1α/CXCR4 axis
-
Song N, Huang Y, Shi H et al.: Overexpression of platelet-derived growth factor-BB increases tumor pericyte content via stromal-derived factor-1α/CXCR4 axis. Cancer Res. 69(15), 6057-6064 (2009).
-
(2009)
Cancer Res.
, vol.69
, Issue.15
, pp. 6057-6064
-
-
Song, N.1
Huang, Y.2
Shi, H.3
|