DLL4 Blockade Inhibits Tumor Growth and Reduces Tumor-Initiating Cell Frequency

Cell Stem Cell

Volumn 5, Issue 2, 2009, Pages 168-177

  Hoey, Timothy ^a   Yen, Wan Ching ^a   Axelrod, Fumiko ^a   Basi, Jesspreet ^a   Donigian, Lucas ^a   Dylla, Scott ^a   Fitch Bruhns, Maureen ^a   Lazetic, Sasha ^a   Park, In Kyung ^a   Sato, Aaron ^a   Satyal, Sanjeev ^a   Wang, Xinhao ^a   Clarke, Michael F ^b   Lewicki, John ^a   Gurney, Austin ^a  

^a OncoMed Pharmaceuticals Inc   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CELLCYCLE; STEMCELL

Indexed keywords

CANCER ANTIBODY; DELTA LIKE 4 LIGAND ANTIBODY; IRINOTECAN; NOTCH RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER STEM CELL; CARCINOGENICITY; COLON TUMOR; CONTROLLED STUDY; DRUG MEGADOSE; DRUG POTENTIATION; DRUG TARGETING; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR CELL; TUMOR XENOGRAFT;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS REGULATORY PROTEINS; CAMPTOTHECIN; CELL LINE, TUMOR; CELL PROLIFERATION; CHAPERONIN 60; DRUG SYNERGISM; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; NEOPLASMS; NEOPLASTIC STEM CELLS; NEOVASCULARIZATION, PATHOLOGIC; RECEPTORS, NOTCH; RECURRENCE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 67849124654     PISSN: 19345909     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stem.2009.05.019     Document Type: Article

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