Inhibition of notch signaling induces neural differentiation in Ewing sarcoma

American Journal of Pathology

Volumn 170, Issue 5, 2007, Pages 1686-1694

  Baliko, Frank ^a   Bright, Tamara ^a   Poon, Raymond ^a   Cohen, Brenda ^a   Egan, Sean E ^a   Alman, Benjamin A ^a,b,c  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c NONE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BROXURIDINE; FLUORESCEIN; GAMMA SECRETASE INHIBITOR; NOTCH1 RECEPTOR; ENZYME INHIBITOR; NOTCH RECEPTOR; SECRETASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER GROWTH; CELL LINE; CELL PROLIFERATION; CLINICAL FEATURE; CONTROLLED STUDY; ENZYME ACTIVITY; EWING SARCOMA; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NERVE CELL DIFFERENTIATION; NEUROECTODERM; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR VOLUME; WESTERN BLOTTING; XENOGRAFT; ANIMAL; BONE TUMOR; CELL DIFFERENTIATION; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSFECTION; METABOLISM; NERVE CELL; NUDE MOUSE; PHYSIOLOGY; TUMOR CELL LINE;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; APOPTOSIS; BONE NEOPLASMS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; ENZYME INHIBITORS; HUMANS; MICE; MICE, NUDE; NEURONS; RECEPTORS, NOTCH; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SARCOMA, EWING'S; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 34250796873     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2007.060971     Document Type: Article

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