Cyclooxygenase-2 participates in the late phase of airway hyperresponsiveness after ozone exposure in guinea pigs

European Journal of Pharmacology

Volumn 403, Issue 3, 2000, Pages 267-275

  Nakano, Hiroyuki ^a,b   Aizawa, Hisamichi ^b   Matsumoto, Koichiro ^a   Fukuyama, Satoru ^a   Inoue, Hiromasa ^a   Hara, Nobuyuki ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b FUKUOKA HIGASHI MEDICAL CENTER   (Japan)

Author keywords

(Guinea pig); Airway hyperresponsiveness; Cyclooxygenase 2; JTE 522; Ozone; Prostaglandin E2; Thromboxane A2; U 46619

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; HISTAMINE; INDOMETACIN; OZONE; PROSTAGLANDIN E2; THROMBOXANE B2; TILMACOXIB;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME INHIBITION; GUINEA PIG; LUNG LAVAGE; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; RESPIRATORY TRACT INFLAMMATION;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ADMINISTRATION, INHALATION; ANIMALS; BENZENESULFONATES; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; CELL COUNT; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; GUINEA PIGS; HISTAMINE; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MALE; OXAZOLES; OXIDANTS, PHOTOCHEMICAL; OZONE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS; THROMBOXANE A2;

EID: 0034623266     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00524-0     Document Type: Article

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