Modulation of silica-induced pulmonary toxicity by dexamethasone- containing liposomes

Toxicology and Applied Pharmacology

Volumn 142, Issue 2, 1997, Pages 411-421

  Dimatteo, Michael ^a   Reasor, Mark J ^a  

^a WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BALANCED SALT SOLUTION; BETA GLUCURONIDASE; BUFFER; DEXAMETHASONE; HYDROXYPROLINE; LACTATE DEHYDROGENASE; LIPOSOME; LUMINOL; PHOSPHATIDYLCHOLINE; SILICON DIOXIDE; SODIUM CHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMOLUMINESCENCE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; INTRATRACHEAL DRUG ADMINISTRATION; LUNG ALVEOLUS MACROPHAGE; LUNG FIBROSIS; LUNG LAVAGE; LUNG TOXICITY; MALE; NEUTROPHIL; NONHUMAN; OCCUPATIONAL EXPOSURE; RAT; SILICOSIS;

ANIMALIA; MARTES PENNANTI;

EID: 0031062289     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1996.8057     Document Type: Article

References (52)

1. Adamson, I. Y. R., Prieditis, H., and Bowden, D. H. (1992). Instillation of chemotactic factor to silica-injected lungs lowers interstitial particle content and reduces pulmonary fibrosis. Am. J. Pathol. 141, 319-326.
2. Antonini, J. M., Van Dyke, K., Ye, Z., DiMatteo, M., and Reasor, M. J. (1994). Introduction of luminol-dependent chemiluminescence as a method to study silica inflammation in the tissue and phagocytic cells of rat lung. Environ. Health Perspect. 102, 37-42.
3. Bates, S. R., Dodia, C., and Fisher, A. B. (1994). Surfactant protein A regulates uptake of pulmonary surfactant by lung type II cells on microporous membranes. Am. J. Physiol. 267, L753-L760.
4. Brain, J. D., Knudson, D. E., Sorokin, S. P., and Davis, M. A. (1976). Pulmonary distribution of particles given by intratracheal instillation or by aerosol inhalation. Environ. Res. 11, 13-33.
5. Chedid, M., Hoyle, J. R., Csaky, K. G., and Rubin, J. S. (1996). Glucocorticoids inhibit keratinocyte growth factor production in primary dermal fibroblasts. Endocrinology 137, 2232-2237.
6. Chen, F., Sun, S. C., Kuh, D. C., Gaydos, L. J., and Demers, L. M. (1995). Essential role of NF-kappa B activation in silica-induced inflammatory mediator production in macrophages. Biochem. Biophys. Res. Commun. 214, 985-992.
7. Chen, Y., Whitney, P. L., and Frank, L. (1993). Negative regulation of antioxidant enzyme gene expression in the developing fetal rat lung by prenatal hormonal treatments. Pediatr. Res. 33, 171-176.
8. Cockayne, D., Sterling, K. M., Jr., Shull, S., Mintz, K. P., Illeyne, S., and Cutroneo, K. R. (1986). Glucocorticoids decrease the synthesis of type I procollagen mRNAs. Biochemistry 25, 3203-3209.
9. Debs, R. J., Straubinger, R. M., Brunette, E. N., Lin, J. M., Lin, E. J., Montgomery, A. B., Friend, D. S., and Papahadjopoulos, D. P. (1987). Selective enhancement of pentamidine uptake in the lung by aerosolization and delivery in liposomes. Am. Rev. Respir. Dis. 135, 731-737.
10. DiMatteo, M., Antonini, J. M., Van Dyke, K., and Reasor, M. J. (1995). Characteristics of the acute-phase pulmonary response to silica in rats. J. Toxicol. Environ. Health. 46, 101-116.
11. Dougall, W. C., and Nick, H. S. (1991). Manganese superoxide dismutase: A hepatic acute phase protein regulated by interleukin-6 and glucocorticoids. Endocrinology. 129, 2376-84.
12. Driscoll, K. E., Lindenschmidt, R. C., Maurer, J. K., Higgins, J. M., and Ridder, G. (1990). Pulmonary response to silica or titanium dioxide: Inflammatory cells, alveolar macrophage-derived cytokines, and histopathology. Am. J. Respir. Cell Mol. Biol. 2, 381-390.
13. Driscoll, K. E., Lindenschmidt, R. C., Maurer, J. K., Perkins, L., Perkins, M., and Higgins, J. (1991). Pulmonary response to inhaled silica or titanium dioxide. Toxicol. Appl. Pharmacol. 111, 201-210.
14. Driscoll, K. E., and Maurer, J. K. (1991). Cytokine and growth factor release by alveolar macrophages: Potential biomarkers of pulmonary toxicity. Toxicol. Pathol. 19, 398-405.
15. DuBois, C. M., Bissonnette, E., and Rola-Pleszczynski, M. (1989). Asbestos fibers and silica particles stimulate rat alveolar macrophages to release tumor necrosis factor. Am. Rev. Respir. Dis. 139, 1257-1264.
16. Fiorentino, D. F., Zlotnik, A., Mosmann, T. R., Howard, M., and O'Garra, A. (1991). IL-10 inhibits cytokine production by activated macrophages. J. Immunol. 147, 3815-3822.
17. Frost, G. H., Rhee, K., Ma, T., and Thompson, E. A. (1994). Expression of c-Myc in glucocorticoid-treated fibroblastic cells. J. Steroid Biochem. Mol. Biol. 50, 109-119.
18. Gonzalez-Rothi, R. J., Straub, L., Cacace, J. L., and Schreier, H. (1991). Liposomes and pulmonary alveolar macrophages: Functional and morphologic interactions. Exp. Lung Res. 17, 687-705.
19. Goodman, G. B., Kaplan, P. D., Stachura, I., Castranova, V., Pailes, W. H., and Lapp, N. L. (1992). Acute silicosis responding to corticosteroid therapy. Chest 101, 366-370.
20. Guyre, P. M., Girard, M. T., Morganelli, P. M., and Manganiello, P. D. (1988). Glucocorticoid effects on the production and actions of immune cytokines. J. Steroid Biochem. 30, 89-93.
21. Heppleston, A. G. (1982). Silicotic fibrogenesis: A concept of pulmonary fibrosis. Ann. Occup. Hyg. 26, 449-462.
22. Janssen, Y. M., Marsh, J. P., Driscoll, K. E., Borm, P. J., Oberdorster, G., and Mossman, B. T. (1994). Increased expression of manganese-containing superoxide dismutase in rat lungs after inhalation of inflammatory and fibrogenic minerals. Free Radicals Biol. Med. 16, 315-22.
23. Janssen, Y. M. W., Marsh, J. P., Absher, M. P., Hemenway, D., Vacek, P. M., Leslie, K. O., Borm, P. J. A., and Mossman, B. T. (1991). Expression of antioxidant enzymes in rat lungs after inhalation of asbestos or silica. J. Biol. Chem. 267, 10625-10630.
24. Kehrl, J. H., and Fauci, A. S. (1983). The clinical use of glucocorticoids. Ann. Allergy. 50, 2-8.
25. Kern, J. A., Lamb, R. J., Reed, J. C., Daniele, R. P., and Nowell, P. C. (1988). Dexamethasone inhibition of interleukin 1 beta production by human monocytes: Posttranscriptional mechanisms. J. Clin. Invest. 81, 237-244.
26. Khan, M. F., and Gupta, G. S. D. (1991). Cellular and biochemical indices of bronchoalveolar lavage for detection of lung injury following insult by airborne toxicants. Toxicol. Lett. 58, 239-255.
27. Kleinert, H., Euchenhofer, C., Ihrig-Biedert, I., and Forstermann, U. (1996). Glucocorticoids inhibit the induction of nitric oxide synthase II by down-regulating cytokine-induced activity of transcription factor nuclear factor-kappa B. Mol. Pharmacol. 49, 15-21.
28. Kuroki, Y., McCormack, F. X., Ogasawara, Y., Mason, R. J., and Voelker, D. R. (1994). Epitope mapping for monoclonal antibodies identifies functional domains of pulmonary surfactant protein A that interact with lipids. J. Biol. Chem. 269, 29793-29800.
29. Lapp, N. L., and Castranova, V. (1993). How silicosis and coal workers' pneumoconiosis develop - A cellular assessment. In Occupational Medicine: State of the Art Reviews (D. E. Banks, Ed.), pp. 35-56. Hanley & Belfus, Philadelphia.
30. Last, J. A., and Reiser, K. M. (1985). Effects of silica on lung collagen. In Silicon Biochemistry (D. Evered and M. O'Conner, Eds.), pp. 180-187. Wiley, New York.
31. Lindenschmidt, R. C., Driscoll, K. E., Perkins, M. A., Higgins, J. M., Maurer, J. K., and Belfiore, K. A. (1990). The comparison of a fibrogenic and two nonfibrogenic dusts by bronchoalveolar lavage. Toxicol. Appl. Pharmacol. 102, 268-281.
32. Lockard, V. G., and Kennedy, R. E. (1976). Alterations in rabbit alveolar macrophages as a result of traumatic shock. Lab. Invest. 35, 501-506.
33. McCormack, F. X., Kuroki, Y., Stewart, J. J., Mason, R. J., and Voelker, D. R. (1994). Surfactant protein A amino acids Glu195 and Arg197 are essential for receptor binding, phospholipid aggregation, regulation of secretion, and the facilitated uptake of phospholipid by type II cells. J. Biol. Chem. 269, 29801-29807.
34. Meisler, N., Shull, S., Xie, R., Long, G. L., Absher, M., Connolly, J. P., and Cutroneo, K. R. (1995). Glucocorticoids coordinately regulate type I collagen pro alpha 1 promoter activity through both the glucocorticoid transforming growth factor β response elements: A novel mechanism of glucocorticoid regulation of eukaryotic genes. J. Cell Biochem. 59, 376-388.
35. Mukaida, N., Harada, A., Yasumoto, K., and Matsushima, K. (1992). Properties of proinflammatory cell type-specific leukocyte chemotactic cytokines, interleukin 8 (IL-8) and monocyte chemotactic and activating factor (MCAF). Microbiol. Immunol. 36, 773-789.
36. Ohtsuka, T., Kubota, A., Hirano, T., Watanabe, K., Yoshida, H., Tsurufuji, M., Iizuka, Y., Konishi, K., and Tsurufuji, S. (1996). Glucocorticoid-mediated gene suppression of rat cytokine-induced neutrophil chemoattractant CINC/gro, a member of the interleukin-8 family, through impairment of NF-kappa B activation. J. Biol. Chem. 271, 1651-1659.
37. Piguet, P. F., Vesin, C., Grau, G. E., and Thompson, R. C. (1993). Interleukin 1 receptor antagonist (IL-1ra) prevents or cures pulmonary fibrosis elicited in mice by bleomycin or silica. Cytokine. 5, 57-61.
38. Poiani, G. J., Greco, M., Choe, J. K., Fox, J. D., and Riley, D. J. (1994). Liposome encapsulation improves the effect of antifibrotic agent in rat lung fibrosis. Am. J. Respir. Crit. Care Med. 150, 1623-1627.
39. Radi, R., Cosgrove, T. P., Beckman, J. S., and Freeman, B. A. (1993). Peroxynitrite-induced luminol chemiluminescence. Biochem. J. 290, 51-57.
40. Reiser, K. M., Hesterberg, T. W., Haschek, W. M., and Last, J. A. (1982). Experimental silicosis. Acute effects of intratracheally instilled quartz on collagen metabolism and morphologic characteristics of rat lungs. Am. J. Pathol. 107, 176-185.
41. Robey, P. G. (1979). Effect of dexamethasone on collagen metabolism in two strains of mice. Biochem. Pharmacol. 28, 2261-2266.
42. Ross, R., Raines, E. W., and Bowen-Pope, D. F. (1986). The biology of platelet-derived growth factor. Cell 46, 155-169.
43. Shek, P. N., Suntres, Z. E., and Brooks, J. I. (1994). Liposomes in pulmonary applications: Physicochemical considerations, pulmonary distribution and antioxidant delivery. J. Drug Target. 2, 431-42.
44. Shull, S., Meisler, N., Absher, M., Phan, S., and Cutroneo, K. (1995). Glucocorticoid-induced down regulation of transforming growth factor beta 1 in adult rat lung fibroblasts. Lung 173, 71-78.
45. Siddiqui, A. A., Jaffar, T., Khan, N., Azami, R., and Waqar, M. A. (1992). Effect of dexamethasone on collagen synthesis in fibroblasts cultured in collagen lattice. Biochem. Soc. Trans. 20, 207S.
46. Torry, D. J., Richards, C. D., Podor, T. J., and Gauldie, J. (1994). Anchorage-independent colony growth of pulmonary fibroblasts derived from fibrotic human lung tissue. J. Clin. Invest. 93, 1525-1532.
47. Tremblay, G. M., Therien, H. M., Rocheleau, H., and Cormier, Y. (1993). Liposomal dexamethasone effectiveness in the treatment of hypersensitivity pneumonitis in mice. Eur. J. Clin. Invest. 23, 656-661.
48. Van Dyke, K., Antonini, J. M., Wu, L., Ye, Z., and Reasor, M. J. (1994). The inhibition of silica-induced lung inflammation by dexamethasone as measured by bronchoalveolar lavage fluid parameters and peroxynitrite-dependent chemiluminescence. Agents Actions 41, 44-49.
49. Van Furth, A. M., Seijmonsbergen, E. M., Langermans, J. A., Van der Meide, P. H., and Van Furth, R. (1995). Effect of xanthine derivates and dexamethasone on Streptococcus pneumoniae-stimulated production of tumor necrosis factor alpha, interleukin-1 beta (IL-1 beta), and IL-10 by human leukocytes. Clin. Diag. Lab. Immunol. 2, 689-692.
50. Van Rooijen, N., and Sanders, A. (1994). Liposome mediated depletion of macrophages: Mechanism of action, preparation of liposomes and applications. J. Immunol. Methods 174, 83-93.
51. Vilcek, J., and Lee, T. H. (1991). Tumor necrosis factor: New insights into the molecular mechanisms of its multiple actions. J. Biol. Chem. 266, 7313-7316.
52. Witschi, H. P., Tryka, A. F., and Lindenschmidt, R. C. (1985). The many faces of an increase in lung collagen. Fundam. Appl. Toxicol. 5, 240-250.