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Volumn 289, Issue 1 33-1, 2005, Pages

Effect of doxycycline on sulfur mustard-induced respiratory lesions in guinea pigs

Author keywords

Blistering agents; Doxycycline; Protease inhibitors; Proteases; Vesicant agents

Indexed keywords

DOXYCYCLINE; GELATINASE; MATRIX METALLOPROTEINASE; MUSTARD GAS; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

EID: 20844462185     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00475.2004     Document Type: Article
Times cited : (55)

References (55)
  • 2
    • 0034570325 scopus 로고    scopus 로고
    • Sulfur mustard toxicity in macrophages: Effect of dexamethasone
    • Amir A, Chapman S, Kadar T, Gozes Y, Sahar R, and Allon N. Sulfur mustard toxicity in macrophages: effect of dexamethasone. J Appl Toxicol 20 Suppl 1: S51-S58, 2000.
    • (2000) J Appl Toxicol , vol.20 , Issue.SUPPL. 1
    • Amir, A.1    Chapman, S.2    Kadar, T.3    Gozes, Y.4    Sahar, R.5    Allon, N.6
  • 4
    • 0009795921 scopus 로고    scopus 로고
    • Treatment' of sulfur mustard (HD)-induced lung injury
    • Anderson DR, Byers SL, and Vesely KR. Treatment' of sulfur mustard (HD)-induced lung injury. J Appl Toxicol 20 Suppl 1: S129-S132, 2000.
    • (2000) J Appl Toxicol , vol.20 , Issue.SUPPL. 1
    • Anderson, D.R.1    Byers, S.L.2    Vesely, K.R.3
  • 5
    • 0000698577 scopus 로고    scopus 로고
    • Systemic administration of candidate antivesicants to protect against topically applied sulfur mustard in the mouse ear vesicant model (MEVM)
    • Babin MC, Ricketts K, Skvorak JP, Gazaway M, Mitcheltree LW, and Casillas RP. Systemic administration of candidate antivesicants to protect against topically applied sulfur mustard in the mouse ear vesicant model (MEVM). J Appl Toxicol 20 Suppl 1: S141-S144, 2000.
    • (2000) J Appl Toxicol , vol.20 , Issue.SUPPL. 1
    • Babin, M.C.1    Ricketts, K.2    Skvorak, J.P.3    Gazaway, M.4    Mitcheltree, L.W.5    Casillas, R.P.6
  • 6
    • 0037013172 scopus 로고    scopus 로고
    • Matrix metalloproteinases: Are they antiatherogenic but proaneurysmal?
    • Bendeck MP. Matrix metalloproteinases: are they antiatherogenic but proaneurysmal? Circ Res 90: 836-837, 2002.
    • (2002) Circ Res , vol.90 , pp. 836-837
    • Bendeck, M.P.1
  • 8
    • 0017184389 scopus 로고
    • A rapid sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M. A rapid sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.1
  • 9
    • 0033389884 scopus 로고    scopus 로고
    • Development of a reactive topical skin protectant
    • Braue EH Jr. Development of a reactive topical skin protectant. J Appl Toxicol 19 Suppl 1: S47-S53, 1999.
    • (1999) J Appl Toxicol , vol.19 , Issue.SUPPL. 1
    • Braue Jr., E.H.1
  • 10
    • 0027988208 scopus 로고
    • Glucocorticoids inhibits sulfur mustard-induced airway muscle hyperresponsiveness to substance P
    • Calvet JH, d'Ortho MP, Jarreau PH, Levame M, Harf A, and Macquin-Mavier I. Glucocorticoids inhibits sulfur mustard-induced airway muscle hyperresponsiveness to substance P. J Appl Physiol 77: 2325-2332, 1994.
    • (1994) J Appl Physiol , vol.77 , pp. 2325-2332
    • Calvet, J.H.1    D'Ortho, M.P.2    Jarreau, P.H.3    Levame, M.4    Harf, A.5    Macquin-Mavier, I.6
  • 14
    • 0025937099 scopus 로고
    • Effect of sulfur mustard on protease activity in human peripheral blood lymphocytes
    • Cowan FM, Broomfield CA, and Smith WJ. Effect of sulfur mustard on protease activity in human peripheral blood lymphocytes. Cell Biol Toxicol 1: 239-248, 1991.
    • (1991) Cell Biol Toxicol , vol.1 , pp. 239-248
    • Cowan, F.M.1    Broomfield, C.A.2    Smith, W.J.3
  • 15
    • 0035986173 scopus 로고    scopus 로고
    • Suppression of sulfur mustard-increased IL-8 in human keratinocyte cell cultures by serine protease inhibitors: Implications for toxicity and medical countermeasures
    • Cowan FM, Broomfield CA, and Smith WJ. Suppression of sulfur mustard-increased IL-8 in human keratinocyte cell cultures by serine protease inhibitors: implications for toxicity and medical countermeasures. Cell Biol Toxicol 18: 175-180, 2002.
    • (2002) Cell Biol Toxicol , vol.18 , pp. 175-180
    • Cowan, F.M.1    Broomfield, C.A.2    Smith, W.J.3
  • 18
  • 19
    • 0033040579 scopus 로고    scopus 로고
    • Characteristics of bronchoalveolar lavage fluid in patients with sulfur mustard gas-induced asthma or chronic bronchitis
    • Emad A and Rezaian GR. Characteristics of bronchoalveolar lavage fluid in patients with sulfur mustard gas-induced asthma or chronic bronchitis. Am J Med 106: 625-628, 1999.
    • (1999) Am J Med , vol.106 , pp. 625-628
    • Emad, A.1    Rezaian, G.R.2
  • 20
    • 5444219883 scopus 로고    scopus 로고
    • Matrix metalloproteinases in cancer: From new functions to improved inhibition strategies
    • Folgueras AR, Pendas AM, Sanchez LM, and Lopez-Otin C. Matrix metalloproteinases in cancer: from new functions to improved inhibition strategies. Int J Dev Biol 48: 411-424, 2004.
    • (2004) Int J Dev Biol , vol.48 , pp. 411-424
    • Folgueras, A.R.1    Pendas, A.M.2    Sanchez, L.M.3    Lopez-Otin, C.4
  • 22
    • 15744389578 scopus 로고    scopus 로고
    • Molecular interactions between matrilysin and the matrix metalloproteinase inhibitor doxycycline investigated by deuterium exchange mass spectrometry
    • Garcia RA, Pantazatos DP, Gessner CR, Go KV, Woods VL Jr, and Villarreal FJ. Molecular interactions between matrilysin and the matrix metalloproteinase inhibitor doxycycline investigated by deuterium exchange mass spectrometry. Mol Pharmacol 67: 1128-1136, 2005.
    • (2005) Mol Pharmacol , vol.67 , pp. 1128-1136
    • Garcia, R.A.1    Pantazatos, D.P.2    Gessner, C.R.3    Go, K.V.4    Woods Jr., V.L.5    Villarreal, F.J.6
  • 23
    • 0032200444 scopus 로고    scopus 로고
    • Tetracyclines inhibit connective tissue breakdown by multiple non-antimicrobial mechanisms
    • Golub LM, Lee HM, Ryan ME, Giannobile WV, Payne J, and Sorsa T. Tetracyclines inhibit connective tissue breakdown by multiple non-antimicrobial mechanisms. Adv Dent Res 12: 12-26, 1998.
    • (1998) Adv Dent Res , vol.12 , pp. 12-26
    • Golub, L.M.1    Lee, H.M.2    Ryan, M.E.3    Giannobile, W.V.4    Payne, J.5    Sorsa, T.6
  • 24
    • 1842559783 scopus 로고    scopus 로고
    • Protection by antioxidants against toxicity and apoptosis induced by the sulphur mustard analog 2-chloroethylethyl sulphide (CEES) in Jurkat T cells and normal human lymphocytes
    • Han S, Espinoza LA, Liao H, Boulares AH, and Smulson ME. Protection by antioxidants against toxicity and apoptosis induced by the sulphur mustard analog 2-chloroethylethyl sulphide (CEES) in Jurkat T cells and normal human lymphocytes. Br J Pharmacol 141: 795-802, 2004.
    • (2004) Br J Pharmacol , vol.141 , pp. 795-802
    • Han, S.1    Espinoza, L.A.2    Liao, H.3    Boulares, A.H.4    Smulson, M.E.5
  • 25
    • 0034751435 scopus 로고    scopus 로고
    • MMP inhibitors: Current developments and future perspectives
    • Hoekstra R, Eskens F, and Verweij J. MMP inhibitors: current developments and future perspectives. Oncologist 6: 415-427, 2001.
    • (2001) Oncologist , vol.6 , pp. 415-427
    • Hoekstra, R.1    Eskens, F.2    Verweij, J.3
  • 26
    • 0038021268 scopus 로고    scopus 로고
    • Doxycycline treatment in a model of early abdominal aortic aneurysm
    • Kaito K, Urayama H, and Watanabe G. Doxycycline treatment in a model of early abdominal aortic aneurysm. Surg Today 33: 426-433, 2003.
    • (2003) Surg Today , vol.33 , pp. 426-433
    • Kaito, K.1    Urayama, H.2    Watanabe, G.3
  • 27
    • 0030631813 scopus 로고    scopus 로고
    • Collagenolytic activity and its sensitivity to doxycycline inhibition in tracheal aspirates of horses with chronic obstructive pulmonary disease
    • Koivunen AL, Maisi P, Konttinen YT, Prikk K, and Sandholm M. Collagenolytic activity and its sensitivity to doxycycline inhibition in tracheal aspirates of horses with chronic obstructive pulmonary disease. Acta Vet Scand 38: 9-16, 1997.
    • (1997) Acta Vet Scand , vol.38 , pp. 9-16
    • Koivunen, A.L.1    Maisi, P.2    Konttinen, Y.T.3    Prikk, K.4    Sandholm, M.5
  • 28
    • 0035857792 scopus 로고    scopus 로고
    • Protective effect of various antioxidants on the toxicity of sulphur mustard administered to mice by inhalation or percutaneous routes
    • Kumar O, Sugendran K, and Vijayaraghavan R. Protective effect of various antioxidants on the toxicity of sulphur mustard administered to mice by inhalation or percutaneous routes. Chem Biol Interact 134: 1-12, 2001.
    • (2001) Chem Biol Interact , vol.134 , pp. 1-12
    • Kumar, O.1    Sugendran, K.2    Vijayaraghavan, R.3
  • 29
    • 2342508338 scopus 로고    scopus 로고
    • Doxycycline reduces airway inflammation and hyperresponsiveness in a murine model of toluene diisocyanate-induced asthma
    • Lee KS, Jin SM, Kim SS, and Lee YC. Doxycycline reduces airway inflammation and hyperresponsiveness in a murine model of toluene diisocyanate-induced asthma. J Allergy Clin Immunol 113: 902-909, 2004.
    • (2004) J Allergy Clin Immunol , vol.113 , pp. 902-909
    • Lee, K.S.1    Jin, S.M.2    Kim, S.S.3    Lee, Y.C.4
  • 30
    • 0031742351 scopus 로고    scopus 로고
    • Diisopropylglutathione ester protects A549 cells from the cytotoxic effects of sulphur mustard
    • Lindsay CD and Hambrook JL. Diisopropylglutathione ester protects A549 cells from the cytotoxic effects of sulphur mustard. Hum Exp Toxicol 17: 606-612, 1998.
    • (1998) Hum Exp Toxicol , vol.17 , pp. 606-612
    • Lindsay, C.D.1    Hambrook, J.L.2
  • 31
    • 0031046452 scopus 로고    scopus 로고
    • Protection of A549 cells against the toxic effects of sulphur mustard by hexamethylenetetramine
    • Lindsay CD and Hambrook JL. Protection of A549 cells against the toxic effects of sulphur mustard by hexamethylenetetramine. Hum Exp Toxicol 16: 106-114, 1997.
    • (1997) Hum Exp Toxicol , vol.16 , pp. 106-114
    • Lindsay, C.D.1    Hambrook, J.L.2
  • 32
    • 0842322808 scopus 로고    scopus 로고
    • Examination of changes in connective tissue macromolecular components of large white pig skin following application of Lewisite vapour
    • Lindsay CD, Hambrook JL, Brown RF, Platt JC, Knight R, and Rice P. Examination of changes in connective tissue macromolecular components of large white pig skin following application of Lewisite vapour. J Appl Toxicol 24: 37-46, 2004.
    • (2004) J Appl Toxicol , vol.24 , pp. 37-46
    • Lindsay, C.D.1    Hambrook, J.L.2    Brown, R.F.3    Platt, J.C.4    Knight, R.5    Rice, P.6
  • 33
    • 0030730317 scopus 로고    scopus 로고
    • Monoisopropylglutathione ester protects A549 cells from the cytotoxic effects of sulphur mustard
    • Lindsay CD, Hambrook JL, and Lailey AF. Monoisopropylglutathione ester protects A549 cells from the cytotoxic effects of sulphur mustard. Hum Exp Toxicol 16: 636-644, 1997.
    • (1997) Hum Exp Toxicol , vol.16 , pp. 636-644
    • Lindsay, C.D.1    Hambrook, J.L.2    Lailey, A.F.3
  • 34
    • 0029866602 scopus 로고    scopus 로고
    • Activation of heat shock factor by alkylating agents is triggered by glutathione depletion and oxidation of protein thiols
    • Liu H, Lightfoot R, and Stevens JL. Activation of heat shock factor by alkylating agents is triggered by glutathione depletion and oxidation of protein thiols. J Biol Chem 271: 4805-4812, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 4805-4812
    • Liu, H.1    Lightfoot, R.2    Stevens, J.L.3
  • 36
    • 4444304939 scopus 로고    scopus 로고
    • Regulation of matrix biology by matrix metalloproteinases
    • Mott JD and Werb Z. Regulation of matrix biology by matrix metalloproteinases. Cuir Opin Cell Biol 16: 558-564, 2004.
    • (2004) Cuir Opin Cell Biol , vol.16 , pp. 558-564
    • Mott, J.D.1    Werb, Z.2
  • 37
    • 0027240582 scopus 로고
    • Inhibition of epithelial cell matrix metalloproteinases by tetracyclines
    • Nip LH, Uitto VJ, and Golub LM. Inhibition of epithelial cell matrix metalloproteinases by tetracyclines. J Periodontal Res 28: 379-385, 1993.
    • (1993) J Periodontal Res , vol.28 , pp. 379-385
    • Nip, L.H.1    Uitto, V.J.2    Golub, L.M.3
  • 38
    • 0034468546 scopus 로고    scopus 로고
    • Effects of iodine on inducible nitric oxide synthase and cyclooxygenase-2 expression in sulfur mustard-induced skin
    • Nyska A, Lomnitski L, Maronpot R, Moomaw C, Brodsky B, Sintov A, and Wormser U. Effects of iodine on inducible nitric oxide synthase and cyclooxygenase-2 expression in sulfur mustard-induced skin. Arch Toxicol 768-774, 2001.
    • (2001) Arch Toxicol , pp. 768-774
    • Nyska, A.1    Lomnitski, L.2    Maronpot, R.3    Moomaw, C.4    Brodsky, B.5    Sintov, A.6    Wormser, U.7
  • 40
    • 0030025802 scopus 로고    scopus 로고
    • Doxycycline inhibition of aneurysmal degeneration in an elastase-induced rat model of abdominal aortic aneurysm: Preservation of aortic elastin associated with suppressed production of 92 kDa gelatinase
    • Petrinec D, Liao S, Holmes DR, Reilly JM, Paks WC, and Thompson RW. Doxycycline inhibition of aneurysmal degeneration in an elastase-induced rat model of abdominal aortic aneurysm: preservation of aortic elastin associated with suppressed production of 92 kDa gelatinase. J Vasc Surg 23: 336-346, 1996.
    • (1996) J Vasc Surg , vol.23 , pp. 336-346
    • Petrinec, D.1    Liao, S.2    Holmes, D.R.3    Reilly, J.M.4    Paks, W.C.5    Thompson, R.W.6
  • 42
    • 0036952731 scopus 로고    scopus 로고
    • Cytokine, chemokine, and matrix metalloproteinase response after sulfur mustard injury to weanling pig skin
    • Sabourin CL, Danne MM, Buxton KL, Casillas RP, and Schlager JJ. Cytokine, chemokine, and matrix metalloproteinase response after sulfur mustard injury to weanling pig skin. J Biochem Mol Toxicol 16: 263-272, 2002.
    • (2002) J Biochem Mol Toxicol , vol.16 , pp. 263-272
    • Sabourin, C.L.1    Danne, M.M.2    Buxton, K.L.3    Casillas, R.P.4    Schlager, J.J.5
  • 43
    • 0031739128 scopus 로고    scopus 로고
    • Characterization of the protective effects of L-nitroarginine methyl ester (L-NAME) against the toxicity of sulphur mustard in vitro
    • Sawyer TW. Characterization of the protective effects of L-nitroarginine methyl ester (L-NAME) against the toxicity of sulphur mustard in vitro. Toxicology 131: 21-32, 1998.
    • (1998) Toxicology , vol.131 , pp. 21-32
    • Sawyer, T.W.1
  • 44
    • 0033105581 scopus 로고    scopus 로고
    • Synergistic protective effects of selected arginine analogues against sulphur mustard toxicity in neuron culture
    • Sawyer TW. Synergistic protective effects of selected arginine analogues against sulphur mustard toxicity in neuron culture. Toxicol Appl Pharmacol 155: 169-176, 1999.
    • (1999) Toxicol Appl Pharmacol , vol.155 , pp. 169-176
    • Sawyer, T.W.1
  • 47
    • 0344483895 scopus 로고    scopus 로고
    • Specificity of inhibition of matrix metalloproteinase activity by doxycycline: Relationship to structure of the enzyme
    • Smith GN Jr, Mickler EA, Hasty KA, and Brandt KD. Specificity of inhibition of matrix metalloproteinase activity by doxycycline: relationship to structure of the enzyme. Arthritis Rheum 42: 1140-1146, 1999.
    • (1999) Arthritis Rheum , vol.42 , pp. 1140-1146
    • Smith Jr., G.N.1    Mickler, E.A.2    Hasty, K.A.3    Brandt, K.D.4
  • 49
    • 0003072751 scopus 로고
    • Battlefield chemical inhalation injury
    • edited by Loke J. New York: Dekker: chapt. 8
    • Urbannetti JS. Battlefield chemical inhalation injury. In: Pathophysiology and Treatment of Inhalation Injuries, edited by Loke J. New York: Dekker: 1988, vol. 34, chapt. 8, p. 281-348.
    • (1988) Pathophysiology and Treatment of Inhalation Injuries , vol.34 , pp. 281-348
    • Urbannetti, J.S.1
  • 50
    • 0037942873 scopus 로고    scopus 로고
    • Inhibition of matrix metalloproteinases by lung TIMP-1 gene transfer limits monocrotaline-induced pulmonary vascular remodeling in rats
    • Vieillard-Baron A, Frisdal E, Raffestin B, Baker AH, Eddahibi S, Adnot S, and D'Ortho MP. Inhibition of matrix metalloproteinases by lung TIMP-1 gene transfer limits monocrotaline-induced pulmonary vascular remodeling in rats. Hum Gene Ther 14: 861-869, 2003.
    • (2003) Hum Gene Ther , vol.14 , pp. 861-869
    • Vieillard-Baron, A.1    Frisdal, E.2    Raffestin, B.3    Baker, A.H.4    Eddahibi, S.5    Adnot, S.6    D'Ortho, M.P.7
  • 51
    • 0037693895 scopus 로고    scopus 로고
    • Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry
    • Visse R and Nagase H. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res 92: 827-839, 2003.
    • (2003) Circ Res , vol.92 , pp. 827-839
    • Visse, R.1    Nagase, H.2
  • 52
    • 0024286955 scopus 로고
    • Scavenging of hypoclorous acid by tetracycline, rifampicin and some other antibiotics: A possible antioxidant action of rifampicin and tetracycline?
    • Wasil M, Halliwell B, and Moorhouse CP. Scavenging of hypoclorous acid by tetracycline, rifampicin and some other antibiotics: a possible antioxidant action of rifampicin and tetracycline? Biochem Pharmacol 37: 775-778, 1988.
    • (1988) Biochem Pharmacol , vol.37 , pp. 775-778
    • Wasil, M.1    Halliwell, B.2    Moorhouse, C.P.3
  • 53
    • 0022362769 scopus 로고
    • Human alveolar macrophages produce a fibroblast-like collagenase and collagenase inhibitor
    • Welgus HG, Campbell EJ, Bar-Shavit Z, Senior RM, and Teitelbaum SL. Human alveolar macrophages produce a fibroblast-like collagenase and collagenase inhibitor. J Clin Invest 76: 219-224, 1985.
    • (1985) J Clin Invest , vol.76 , pp. 219-224
    • Welgus, H.G.1    Campbell, E.J.2    Bar-Shavit, Z.3    Senior, R.M.4    Teitelbaum, S.L.5
  • 54
    • 0003301355 scopus 로고
    • Clinical management of mustard gas casualties
    • Willems JL. Clinical management of mustard gas casualties. Ann Med Milit (Belg) 3 Suppl: 1-61, 1989.
    • (1989) Ann Med Milit (Belg) , vol.3 , Issue.SUPPL. , pp. 1-61
    • Willems, J.L.1


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