-
1
-
-
0028842742
-
Prostaglandin endoperoxide synthases -1 and -2
-
Otto J.C., Smith W.L. Prostaglandin endoperoxide synthases -1 and -2. J Lipid Mediat Cell Signal 1995, 12:139-156.
-
(1995)
J Lipid Mediat Cell Signal
, vol.12
, pp. 139-156
-
-
Otto, J.C.1
Smith, W.L.2
-
2
-
-
1842690846
-
On the evolutionary origin of cyclooxygenase (COX) enzymes: characterization of marine invertebrate COX genes points to independent duplication events in vertebrate and invertebrate lineages
-
Jarvin R., Jarvin I., Kurg R., Brash A.R., Samel N. On the evolutionary origin of cyclooxygenase (COX) enzymes: characterization of marine invertebrate COX genes points to independent duplication events in vertebrate and invertebrate lineages. J Biol Chem 2004, 279:13624-13633.
-
(2004)
J Biol Chem
, vol.279
, pp. 13624-13633
-
-
Jarvin, R.1
Jarvin, I.2
Kurg, R.3
Brash, A.R.4
Samel, N.5
-
3
-
-
0345686711
-
Identification and characterization of a cyclo-oxygenase-like enzyme from Entamoeba histolytica
-
Dey I., Keller K., Beley A., Chadee K. Identification and characterization of a cyclo-oxygenase-like enzyme from Entamoeba histolytica. Proc Natl Acad Sci USA 2003, 100:13561-13566.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 13561-13566
-
-
Dey, I.1
Keller, K.2
Beley, A.3
Chadee, K.4
-
4
-
-
0017745730
-
Induction of fatty acid cyclo-oxygenase activity in canine kidney cells (MDCK) by benzo (a) pyrene
-
Hassid A., Levine L. Induction of fatty acid cyclo-oxygenase activity in canine kidney cells (MDCK) by benzo (a) pyrene. J Biol Chem 1977, 252:6591-6593.
-
(1977)
J Biol Chem
, vol.252
, pp. 6591-6593
-
-
Hassid, A.1
Levine, L.2
-
5
-
-
0017359984
-
Prostaglandin production by methylcholanthrene-transformed mouse BALB/3T3. Requirement for protein synthesis
-
Pong S.S., Hong S.L., Levine L. Prostaglandin production by methylcholanthrene-transformed mouse BALB/3T3. Requirement for protein synthesis. J Biol Chem 1977, 252:1408-1433.
-
(1977)
J Biol Chem
, vol.252
, pp. 1408-1433
-
-
Pong, S.S.1
Hong, S.L.2
Levine, L.3
-
6
-
-
0017803324
-
Stimulation of prostaglandin synthesis by tumor-promoting phorbol-12, 1-diesters in canine kidney (MDCK) cells. Cycloheximide inhibits the stimulated prostaglandin synthesis, deacylation of lipids, and morphological changes
-
Ohichi K., Levine L. Stimulation of prostaglandin synthesis by tumor-promoting phorbol-12, 1-diesters in canine kidney (MDCK) cells. Cycloheximide inhibits the stimulated prostaglandin synthesis, deacylation of lipids, and morphological changes. J Biol Chem 1978, 253:4783-4790.
-
(1978)
J Biol Chem
, vol.253
, pp. 4783-4790
-
-
Ohichi, K.1
Levine, L.2
-
7
-
-
0025754779
-
Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
-
Xie W.L., Chipman J.G., Robertson D.L., Erikson R.L., Simmons D.L. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc Natl Acad Sci USA 1991, 88:2692-2696.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 2692-2696
-
-
Xie, W.L.1
Chipman, J.G.2
Robertson, D.L.3
Erikson, R.L.4
Simmons, D.L.5
-
8
-
-
0025871150
-
TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
-
Kujubu D.A., Fletcher B.S., Varnum B.C., Lim R.W., Herschman H.R. TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J Biol Chem 1991, 266:12866-12872.
-
(1991)
J Biol Chem
, vol.266
, pp. 12866-12872
-
-
Kujubu, D.A.1
Fletcher, B.S.2
Varnum, B.C.3
Lim, R.W.4
Herschman, H.R.5
-
9
-
-
0026702494
-
Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase
-
Fletcher B.S., Kujubu D.A., Perrin D.M., Herschman H.R. Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase. J Biol Chem 1992, 267:4338-4344.
-
(1992)
J Biol Chem
, vol.267
, pp. 4338-4344
-
-
Fletcher, B.S.1
Kujubu, D.A.2
Perrin, D.M.3
Herschman, H.R.4
-
11
-
-
0028180129
-
T. Induction of cyclooxygenase-2 by interleukin-1 alpha. Evidence for post-transcriptional regulation.
-
Ristimaki A., Garfinkel S., Wessendorf J., Maciag T., Hla T. T. Induction of cyclooxygenase-2 by interleukin-1 alpha. Evidence for post-transcriptional regulation. J Biol Chem 1994, 269:11769-11775.
-
(1994)
J Biol Chem
, vol.269
, pp. 11769-11775
-
-
Ristimaki, A.1
Garfinkel, S.2
Wessendorf, J.3
Maciag, T.4
Hla, T.5
-
12
-
-
0027468941
-
Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines
-
Jones D.A., Carlton D.P., McIntyre T.M., Zimmerman G.A., Prescott S.M. Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines. J Biol Chem 1993, 268:9049-9054.
-
(1993)
J Biol Chem
, vol.268
, pp. 9049-9054
-
-
Jones, D.A.1
Carlton, D.P.2
McIntyre, T.M.3
Zimmerman, G.A.4
Prescott, S.M.5
-
13
-
-
0027944075
-
Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain
-
Seibert K., Zhang Y., Leahy K., et al. Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain. Proc Natl Acad Sci USA 1994, 91:12013-12017.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12013-12017
-
-
Seibert, K.1
Zhang, Y.2
Leahy, K.3
-
14
-
-
0033590207
-
The role of cyclooxygenases in inflammation, cancer, and development
-
Williams C.S., Mann M., DuBois R.N. The role of cyclooxygenases in inflammation, cancer, and development. Oncogene 1999, 18:7908-7916.
-
(1999)
Oncogene
, vol.18
, pp. 7908-7916
-
-
Williams, C.S.1
Mann, M.2
DuBois, R.N.3
-
15
-
-
0029995029
-
COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex
-
Kaufmann W.E., Worley P.F., Pegg J., Bremer M., Isakson P. COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex. Proc Natl Acad Sci USA 1996, 93:2317-2321.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2317-2321
-
-
Kaufmann, W.E.1
Worley, P.F.2
Pegg, J.3
Bremer, M.4
Isakson, P.5
-
16
-
-
0028034970
-
Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction
-
Harris R.C., McKanna J.A., Akai Y., Jacobson H.R., Dubois R.N., Breyer M.D. Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. J Clin Invest 1994, 94:2504-2510.
-
(1994)
J Clin Invest
, vol.94
, pp. 2504-2510
-
-
Harris, R.C.1
McKanna, J.A.2
Akai, Y.3
Jacobson, H.R.4
Dubois, R.N.5
Breyer, M.D.6
-
17
-
-
0028818913
-
Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II
-
Dinchuk J.E., Car B.D., Focht R.J., et al. Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II. Nature 1995, 378:406-409.
-
(1995)
Nature
, vol.378
, pp. 406-409
-
-
Dinchuk, J.E.1
Car, B.D.2
Focht, R.J.3
-
18
-
-
0033150517
-
Enhanced bradykinin-stimulated prostaglandin release in the acutely inflamed guinea pig gallbladder is due to new synthesis of cyclooxygenase-1 and prostacyclin synthase
-
Bogar L.J., Bartula L.L., Parkman H.P., Myers S.I. Enhanced bradykinin-stimulated prostaglandin release in the acutely inflamed guinea pig gallbladder is due to new synthesis of cyclooxygenase-1 and prostacyclin synthase. J Surg Res 1999, 84:71-76.
-
(1999)
J Surg Res
, vol.84
, pp. 71-76
-
-
Bogar, L.J.1
Bartula, L.L.2
Parkman, H.P.3
Myers, S.I.4
-
19
-
-
0031556937
-
Induction of cyclooxygenase-1 in a human megakaryoblastic cell line (CMK) differentiated by phorbol ester
-
Ueda N., Yamashita R., Yamamoto S., Ishimura K. Induction of cyclooxygenase-1 in a human megakaryoblastic cell line (CMK) differentiated by phorbol ester. Biochim Biophys Acta 1997, 1344:103-110.
-
(1997)
Biochim Biophys Acta
, vol.1344
, pp. 103-110
-
-
Ueda, N.1
Yamashita, R.2
Yamamoto, S.3
Ishimura, K.4
-
20
-
-
0032839061
-
Cyclooxygenase knockout mice: models for elucidating isoform-specific functions
-
Langenbach R., Loftin C., Lee C., Tiano H. Cyclooxygenase knockout mice: models for elucidating isoform-specific functions. Biochem Pharmacol 1999, 58:1237-1246.
-
(1999)
Biochem Pharmacol
, vol.58
, pp. 1237-1246
-
-
Langenbach, R.1
Loftin, C.2
Lee, C.3
Tiano, H.4
-
21
-
-
0027993458
-
Up-regulation of cyclooxygenase-2 gene expression in human colorectal adenomas and adenocarcinomas
-
Eberhart C.E., Coffey R.J., Radhika A., Giardiello F.M., Ferrenbach S., DuBois R.N. Up-regulation of cyclooxygenase-2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 1994, 107:1183-1188.
-
(1994)
Gastroenterology
, vol.107
, pp. 1183-1188
-
-
Eberhart, C.E.1
Coffey, R.J.2
Radhika, A.3
Giardiello, F.M.4
Ferrenbach, S.5
DuBois, R.N.6
-
22
-
-
0032893269
-
Cyclooxygenase-2 expression in human esophageal carcinoma
-
Zimmermann K.C., Sarbia M., Weber A.A., Borchard F., Gabbert H.E., Schror K. Cyclooxygenase-2 expression in human esophageal carcinoma. Cancer Res 1999, 59:198-204.
-
(1999)
Cancer Res
, vol.59
, pp. 198-204
-
-
Zimmermann, K.C.1
Sarbia, M.2
Weber, A.A.3
Borchard, F.4
Gabbert, H.E.5
Schror, K.6
-
23
-
-
0033106051
-
Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer
-
Tucker O.N., Dannenberg A.J., Yang E.K., et al. Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer. Cancer Res 1999, 59:987-990.
-
(1999)
Cancer Res
, vol.59
, pp. 987-990
-
-
Tucker, O.N.1
Dannenberg, A.J.2
Yang, E.K.3
-
24
-
-
3142587657
-
Analysis of cyclo-oxygenase-2 (COX-2) expression during malignant melanoma progression
-
Goulet A.C., Einsphar J.G., Alberts D.S., et al. Analysis of cyclo-oxygenase-2 (COX-2) expression during malignant melanoma progression. Cancer Biol Ther 2003, 2:713-718.
-
(2003)
Cancer Biol Ther
, vol.2
, pp. 713-718
-
-
Goulet, A.C.1
Einsphar, J.G.2
Alberts, D.S.3
-
25
-
-
0035360795
-
Cyclooxygenase-2 expression in human gliomas: prognostic significance and molecular correlations
-
Shono T., Tofilon P.J., Bruner J.M., Owolabi O., Lang F.F. Cyclooxygenase-2 expression in human gliomas: prognostic significance and molecular correlations. Cancer Res 2001, 61:4375-4381.
-
(2001)
Cancer Res
, vol.61
, pp. 4375-4381
-
-
Shono, T.1
Tofilon, P.J.2
Bruner, J.M.3
Owolabi, O.4
Lang, F.F.5
-
26
-
-
0032170955
-
Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas
-
Hida T., Yatabe Y., Achiwa H., et al. Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas. Cancer Res 1998, 58:3761-3764.
-
(1998)
Cancer Res
, vol.58
, pp. 3761-3764
-
-
Hida, T.1
Yatabe, Y.2
Achiwa, H.3
-
27
-
-
52949102543
-
Targeting cyclooxygenase-2 in hematological malignancies: rationale and promise
-
Bernard M.P., Bancos S., Sime P.J., Phipps R.P. Targeting cyclooxygenase-2 in hematological malignancies: rationale and promise. Curr Pharm Des 2008, 14:2051-2060.
-
(2008)
Curr Pharm Des
, vol.14
, pp. 2051-2060
-
-
Bernard, M.P.1
Bancos, S.2
Sime, P.J.3
Phipps, R.P.4
-
28
-
-
0028047951
-
Characterization of the genomic structure, chromosomal location and promoter of human prostaglandin H synthase-2 gene
-
Tazawa R., Xu X.M., Wu K.K., Wang L.H. Characterization of the genomic structure, chromosomal location and promoter of human prostaglandin H synthase-2 gene. Biochem Biophys Res Commun 1994, 203:190-199.
-
(1994)
Biochem Biophys Res Commun
, vol.203
, pp. 190-199
-
-
Tazawa, R.1
Xu, X.M.2
Wu, K.K.3
Wang, L.H.4
-
29
-
-
0028147767
-
Structure of the human cyclo-oxygenase-2 gene
-
Appleby S.B., Ristimaki A., Neilson K., Narko K., Hla T. Structure of the human cyclo-oxygenase-2 gene. Biochem J 1994, 302:723-727.
-
(1994)
Biochem J
, vol.302
, pp. 723-727
-
-
Appleby, S.B.1
Ristimaki, A.2
Neilson, K.3
Narko, K.4
Hla, T.5
-
30
-
-
27544432733
-
Cyclooxygenase variants: the role of alternative splicing
-
Roos K.L.T., Simmons D.L. Cyclooxygenase variants: the role of alternative splicing. Biochem Biophys Res Commun 2005, 338:62-69.
-
(2005)
Biochem Biophys Res Commun
, vol.338
, pp. 62-69
-
-
Roos, K.L.T.1
Simmons, D.L.2
-
31
-
-
77951018691
-
Cyclooxygenase-2 genetic variants are associated with survival in unresectable locally advanced non-small cell lung cancer
-
Bi N., Yang M., Zhang L., et al. Cyclooxygenase-2 genetic variants are associated with survival in unresectable locally advanced non-small cell lung cancer. Clin Cancer Res 2010, 16:2383-2390.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2383-2390
-
-
Bi, N.1
Yang, M.2
Zhang, L.3
-
32
-
-
0026588059
-
Prostaglandin endoperoxide synthase gene structure: identification of the transcriptional start site and 5'-flanking regulatory sequences
-
Kraemer S.A., Meade E.A., DeWitt D.L. Prostaglandin endoperoxide synthase gene structure: identification of the transcriptional start site and 5'-flanking regulatory sequences. Arch Biochem Biophys 1992, 293:391-400.
-
(1992)
Arch Biochem Biophys
, vol.293
, pp. 391-400
-
-
Kraemer, S.A.1
Meade, E.A.2
DeWitt, D.L.3
-
33
-
-
0028788194
-
AU-rich elements: characterization and importance in mRNA degradation
-
Chen C.Y., Shyu A.B. AU-rich elements: characterization and importance in mRNA degradation. Trends Biochem Sci 1995, 20:465-470.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 465-470
-
-
Chen, C.Y.1
Shyu, A.B.2
-
35
-
-
0029911267
-
Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2
-
Luong C., Miller A., Barnett J., Chow J., Ramesha C., Browner M.F. Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2. Nat Struct Biol 1996, 3:927-933.
-
(1996)
Nat Struct Biol
, vol.3
, pp. 927-933
-
-
Luong, C.1
Miller, A.2
Barnett, J.3
Chow, J.4
Ramesha, C.5
Browner, M.F.6
-
36
-
-
33845991203
-
The 19-amino acid cassette of cyclooxygenase-2 mediates entry of the protein into the endoplasmic reticulum-associated degradation system
-
Mbonye U.R., Wada M., Rieke C.J., Tang H.-Y., Dewitt D.L., Smith W.L. The 19-amino acid cassette of cyclooxygenase-2 mediates entry of the protein into the endoplasmic reticulum-associated degradation system. J Biol Chem 2006, 281:35770-35778.
-
(2006)
J Biol Chem
, vol.281
, pp. 35770-35778
-
-
Mbonye, U.R.1
Wada, M.2
Rieke, C.J.3
Tang, H.-Y.4
Dewitt, D.L.5
Smith, W.L.6
-
37
-
-
0027327231
-
N-glycosylation of prostaglandin endoperoxide synthases-1 and -2 and their orientations in the endoplasmic reticulum
-
Otto J.C., DeWitt D.L., Smith W.L. N-glycosylation of prostaglandin endoperoxide synthases-1 and -2 and their orientations in the endoplasmic reticulum. J Biol Chem 1993, 268:18234-18242.
-
(1993)
J Biol Chem
, vol.268
, pp. 18234-18242
-
-
Otto, J.C.1
DeWitt, D.L.2
Smith, W.L.3
-
38
-
-
34848904215
-
Glycosylation regulates turnover of cyclooxygenase-2
-
Sevigny M.B., Li C.-F., Alas M., Hughes-Fulford M. Glycosylation regulates turnover of cyclooxygenase-2. FEBS Lett 2006, 580:6533-6536.
-
(2006)
FEBS Lett
, vol.580
, pp. 6533-6536
-
-
Sevigny, M.B.1
Li, C.-F.2
Alas, M.3
Hughes-Fulford, M.4
-
39
-
-
29344465714
-
Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2
-
Kim S.F., Huri D.A., Snyder S.H. Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2. Science 2005, 310:1966-1970.
-
(2005)
Science
, vol.310
, pp. 1966-1970
-
-
Kim, S.F.1
Huri, D.A.2
Snyder, S.H.3
-
40
-
-
0028969527
-
Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2
-
Morita I., Schindler M., Regier M.K., et al. Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2. J Biol Chem 1995, 270:10902-10908.
-
(1995)
J Biol Chem
, vol.270
, pp. 10902-10908
-
-
Morita, I.1
Schindler, M.2
Regier, M.K.3
-
41
-
-
4544320012
-
Prostaglandin E2 promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta
-
Wang D., Wang H., Shi Q., et al. Prostaglandin E2 promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta. Cancer Cell 2004, 6:285-295.
-
(2004)
Cancer Cell
, vol.6
, pp. 285-295
-
-
Wang, D.1
Wang, H.2
Shi, Q.3
-
42
-
-
18844462488
-
Mitochondrial localization of cyclooxygenase-2 and calcium-independent phospholipase A2 in human cancer cells: implication in apoptosis resistance
-
Liou J.-Y., Aleksic N., Chen S.-F., Han T.-J., Shyue S.-K., Wu K.K. Mitochondrial localization of cyclooxygenase-2 and calcium-independent phospholipase A2 in human cancer cells: implication in apoptosis resistance. Exp Cell Res 2005, 306:75-84.
-
(2005)
Exp Cell Res
, vol.306
, pp. 75-84
-
-
Liou, J.-Y.1
Aleksic, N.2
Chen, S.-F.3
Han, T.-J.4
Shyue, S.-K.5
Wu, K.K.6
-
43
-
-
40949096164
-
Lipid bodies are reservoirs of cyclooxygenase-2 and sites of prostaglandin-E2 synthesis in colon cancer cells
-
Accioly M.T., Pacheco P., Maya-Monteiro C.M., et al. Lipid bodies are reservoirs of cyclooxygenase-2 and sites of prostaglandin-E2 synthesis in colon cancer cells. Cancer Res 2008, 68:1732-1740.
-
(2008)
Cancer Res
, vol.68
, pp. 1732-1740
-
-
Accioly, M.T.1
Pacheco, P.2
Maya-Monteiro, C.M.3
-
44
-
-
0022555865
-
Arachidonic acid metabolism
-
Needleman P., Turk J., Jakschik B.A., Morrison A.R., Lefkowith J.B. Arachidonic acid metabolism. Annu Rev Biochem 1986, 55:69-102.
-
(1986)
Annu Rev Biochem
, vol.55
, pp. 69-102
-
-
Needleman, P.1
Turk, J.2
Jakschik, B.A.3
Morrison, A.R.4
Lefkowith, J.B.5
-
45
-
-
0033535371
-
Lipid peroxidation-DNA damage by malondialdehyde
-
Marnett L.J. Lipid peroxidation-DNA damage by malondialdehyde. Mutat Res 1999, 424:83-95.
-
(1999)
Mutat Res
, vol.424
, pp. 83-95
-
-
Marnett, L.J.1
-
46
-
-
43749115768
-
Non-redundant functions of cyclooxygenases: oxygenation of endocannabinoids
-
Rouzer C.A., Marnett L.J. Non-redundant functions of cyclooxygenases: oxygenation of endocannabinoids. J Biol Chem 2008, 283:8065-8069.
-
(2008)
J Biol Chem
, vol.283
, pp. 8065-8069
-
-
Rouzer, C.A.1
Marnett, L.J.2
-
47
-
-
0028339780
-
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
-
Lecomte M., Laneuville O., Ji C., DeWitt D.L., Smith W.L. Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin. J Biol Chem 1994, 269:13207-13215.
-
(1994)
J Biol Chem
, vol.269
, pp. 13207-13215
-
-
Lecomte, M.1
Laneuville, O.2
Ji, C.3
DeWitt, D.L.4
Smith, W.L.5
-
48
-
-
31444446617
-
Convergent oxygenation of arachidonic acid by 5-lipoxygenase and cyclooxygenase-2
-
Schneider C., Boeglin W.E., Yin H., Stec D.F., Voehler M. Convergent oxygenation of arachidonic acid by 5-lipoxygenase and cyclooxygenase-2. J Am Chem Soc 2006, 128:720-721.
-
(2006)
J Am Chem Soc
, vol.128
, pp. 720-721
-
-
Schneider, C.1
Boeglin, W.E.2
Yin, H.3
Stec, D.F.4
Voehler, M.5
-
49
-
-
0035142384
-
Carcinogen substrate specificity of human COX-1 and COX-2
-
Wiese F.W., Thompson P.A., Kadlubar F.F. Carcinogen substrate specificity of human COX-1 and COX-2. Carcinogenesis 2001, 22:5-10.
-
(2001)
Carcinogenesis
, vol.22
, pp. 5-10
-
-
Wiese, F.W.1
Thompson, P.A.2
Kadlubar, F.F.3
-
50
-
-
0033710249
-
Immunohistochemical localization of cyclooxygenase-1 and cyclooxygenase-2 in the human fetal and adult male reproductive tracts
-
Kirschenbaum A., Liotta D.R., Yao S., et al. Immunohistochemical localization of cyclooxygenase-1 and cyclooxygenase-2 in the human fetal and adult male reproductive tracts. J Clin Endocrinol Metab 2000, 85:3436-3441.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 3436-3441
-
-
Kirschenbaum, A.1
Liotta, D.R.2
Yao, S.3
-
51
-
-
0034283944
-
TNF-alpha-induced cyclooxygenase-2 expression in human lung epithelial cells: involvement of the phospholipase C-gamma 2, protein kinase C-alpha, tyrosine kinase, NF-kappa B-inducing kinase, and I-kappa B kinase 1/2 pathway
-
Chen C.C., Sun Y.T., Chen J.J., Chiu K.T. TNF-alpha-induced cyclooxygenase-2 expression in human lung epithelial cells: involvement of the phospholipase C-gamma 2, protein kinase C-alpha, tyrosine kinase, NF-kappa B-inducing kinase, and I-kappa B kinase 1/2 pathway. J Immunol 2000, 165:2719-2728.
-
(2000)
J Immunol
, vol.165
, pp. 2719-2728
-
-
Chen, C.C.1
Sun, Y.T.2
Chen, J.J.3
Chiu, K.T.4
-
52
-
-
0029888972
-
Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis
-
Anderson G.D., Hauser S.D., McGarity K.L., Bremer M.E., Isakson P.C., Gregory S.A. Selective inhibition of cyclooxygenase (COX)-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis. J Clin Invest 1996, 97:2672-2679.
-
(1996)
J Clin Invest
, vol.97
, pp. 2672-2679
-
-
Anderson, G.D.1
Hauser, S.D.2
McGarity, K.L.3
Bremer, M.E.4
Isakson, P.C.5
Gregory, S.A.6
-
53
-
-
23944436934
-
Long-term use of aspirin and nonsteroidal anti-inflammatory drugs and risk of colorectal cancer
-
Chan A.T., Giovannucci E.L., Meyerhardt J.A., Schernhammer E.S., Curhan G.C., Fuchs C.S. Long-term use of aspirin and nonsteroidal anti-inflammatory drugs and risk of colorectal cancer. JAMA 2005, 294:914-923.
-
(2005)
JAMA
, vol.294
, pp. 914-923
-
-
Chan, A.T.1
Giovannucci, E.L.2
Meyerhardt, J.A.3
Schernhammer, E.S.4
Curhan, G.C.5
Fuchs, C.S.6
-
54
-
-
77956240092
-
Use of aspirin and other nonsteroidal antiinflammatoy medications in relation to prostate cancer risk
-
Salinas C.A., Kwon E.M., Fitzferald L.M., et al. Use of aspirin and other nonsteroidal antiinflammatoy medications in relation to prostate cancer risk. Am J Epidemiol 2010, 172:578-590.
-
(2010)
Am J Epidemiol
, vol.172
, pp. 578-590
-
-
Salinas, C.A.1
Kwon, E.M.2
Fitzferald, L.M.3
-
55
-
-
0035805054
-
Breast cancer and NSAID use: a meta-analysis
-
Khuder S.A., Mutgi A.B. Breast cancer and NSAID use: a meta-analysis. Br J Cancer 2001, 84:1188-1192.
-
(2001)
Br J Cancer
, vol.84
, pp. 1188-1192
-
-
Khuder, S.A.1
Mutgi, A.B.2
-
56
-
-
1342312264
-
Aspirin and the risk of Hodgkin's lymphoma in a population-based case-control study
-
Chang E.T., Zheng T., Weir E.G., et al. Aspirin and the risk of Hodgkin's lymphoma in a population-based case-control study. J Natl Cancer Inst 2004, 96:305-315.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 305-315
-
-
Chang, E.T.1
Zheng, T.2
Weir, E.G.3
-
57
-
-
0029964295
-
Sulindac induced regression of colorectal adenomas in familial adenomatous polyposis: evaluation of predictive factors
-
Giardiello F.M., Offerhaus J.A., Tersmette A.C., et al. Sulindac induced regression of colorectal adenomas in familial adenomatous polyposis: evaluation of predictive factors. Gut 1996, 38:578-581.
-
(1996)
Gut
, vol.38
, pp. 578-581
-
-
Giardiello, F.M.1
Offerhaus, J.A.2
Tersmette, A.C.3
-
58
-
-
17744418769
-
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
-
Steinbach G., Lynch P.M., Phillips R.K.S., et al. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N Engl J Med 2000, 342:1946-1952.
-
(2000)
N Engl J Med
, vol.342
, pp. 1946-1952
-
-
Steinbach, G.1
Lynch, P.M.2
Phillips, R.K.S.3
-
59
-
-
0034098691
-
Biology of the adenomatous polyposis coli tumor suppressor
-
Goss K.H., Groden J. Biology of the adenomatous polyposis coli tumor suppressor. J Clin Oncol 2000, 18:1967-1979.
-
(2000)
J Clin Oncol
, vol.18
, pp. 1967-1979
-
-
Goss, K.H.1
Groden, J.2
-
60
-
-
68849123400
-
Aspirin use and survival after diagnosis of colorectal cancer
-
Chan A.T., Ogino S., Fuchs C.S. Aspirin use and survival after diagnosis of colorectal cancer. JAMA 2009, 302:649-658.
-
(2009)
JAMA
, vol.302
, pp. 649-658
-
-
Chan, A.T.1
Ogino, S.2
Fuchs, C.S.3
-
61
-
-
77951921896
-
Aspirin intake and survival after breast cancer
-
Holmes M.D., Chen W.Y., Li L., Hertzmark E., Spiegelman D., Hankinson S.E. Aspirin intake and survival after breast cancer. J Clin Oncol 2010, 28:1467-1472.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1467-1472
-
-
Holmes, M.D.1
Chen, W.Y.2
Li, L.3
Hertzmark, E.4
Spiegelman, D.5
Hankinson, S.E.6
-
62
-
-
77952236681
-
COX-2 is overexpressed in primary prostate cancer with metastatic potential and may predict survival. A comparison study between COX-2, TGF-beta, IL-10 and Ki67
-
Richardsen E., Uglehus R.D., Due J., Busch C., Busund L.-T. COX-2 is overexpressed in primary prostate cancer with metastatic potential and may predict survival. A comparison study between COX-2, TGF-beta, IL-10 and Ki67. Cancer Epidemiol 2010, 34:316-322.
-
(2010)
Cancer Epidemiol
, vol.34
, pp. 316-322
-
-
Richardsen, E.1
Uglehus, R.D.2
Due, J.3
Busch, C.4
Busund, L.-T.5
-
63
-
-
77951023237
-
COX-2 is associated with proliferation and apoptosis markers and serves as an independent prognostic factor in gastric cancer
-
Mrena J., Wiksten J.-P., Kokkola A., Nordling S., Ristimaki A., Haglund C. COX-2 is associated with proliferation and apoptosis markers and serves as an independent prognostic factor in gastric cancer. Tumour Biol 2010, 31:1-7.
-
(2010)
Tumour Biol
, vol.31
, pp. 1-7
-
-
Mrena, J.1
Wiksten, J.-P.2
Kokkola, A.3
Nordling, S.4
Ristimaki, A.5
Haglund, C.6
-
64
-
-
33745929929
-
Has Cox-2 a prognostic role in non-small-cell lung cancer? A systematic review of the literature with meta-analysis of the survival results
-
Mascaux C., Martin B., Paesmans M., et al. Has Cox-2 a prognostic role in non-small-cell lung cancer? A systematic review of the literature with meta-analysis of the survival results. Br J Cancer 2006, 95:139-145.
-
(2006)
Br J Cancer
, vol.95
, pp. 139-145
-
-
Mascaux, C.1
Martin, B.2
Paesmans, M.3
-
65
-
-
0038010530
-
Elevated expression of cyclooxygenase-2 is a negative prognostic factor for disease free survival and overall survival in patients with breast carcinoma
-
Denkert C., Winzer K.-J., Muller B.-M., et al. Elevated expression of cyclooxygenase-2 is a negative prognostic factor for disease free survival and overall survival in patients with breast carcinoma. Cancer 2003, 97:2978-2987.
-
(2003)
Cancer
, vol.97
, pp. 2978-2987
-
-
Denkert, C.1
Winzer, K.-J.2
Muller, B.-M.3
-
66
-
-
22344456057
-
Cyclooxygenase-2 expression in postmastectomy chest wall relapse
-
Kim J.H., Bossuyt V., Ponn T., Lannin D., Haffty B.G. Cyclooxygenase-2 expression in postmastectomy chest wall relapse. Clin Cancer Res 2005, 11:5199-5205.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5199-5205
-
-
Kim, J.H.1
Bossuyt, V.2
Ponn, T.3
Lannin, D.4
Haffty, B.G.5
-
67
-
-
67649300721
-
Genes that mediate breast cancer metastasis to the brain
-
Bos P.D., Zhang X.H.F., Nadal C., et al. Genes that mediate breast cancer metastasis to the brain. Nature 2009, 459:1005-1009.
-
(2009)
Nature
, vol.459
, pp. 1005-1009
-
-
Bos, P.D.1
Zhang, X.H.F.2
Nadal, C.3
-
68
-
-
41449092563
-
Association between cyclooxygenase-2 expression in atypical hyperplasia and risk of breast cancer
-
Visscher D.W., Pankratz V.S., Santisteban M., et al. Association between cyclooxygenase-2 expression in atypical hyperplasia and risk of breast cancer. J Natl Cancer Inst 2008, 100:421-427.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 421-427
-
-
Visscher, D.W.1
Pankratz, V.S.2
Santisteban, M.3
-
69
-
-
0036124320
-
Expression of cyclo-oxygenase-2 is an independent prognostic factor in human ovarian carcinoma
-
Denkert C., Kobel M., Pest S., et al. Expression of cyclo-oxygenase-2 is an independent prognostic factor in human ovarian carcinoma. Am J Pathol 2002, 160:893-903.
-
(2002)
Am J Pathol
, vol.160
, pp. 893-903
-
-
Denkert, C.1
Kobel, M.2
Pest, S.3
-
70
-
-
12144290754
-
Synchronous coexpression of epidermal growth factor receptor and cyclooxygenase-2 in carcinomas of the uterine cervix: a potential predictor of poor survival
-
Kim G.E., Kim Y.B., Cho N.H., et al. Synchronous coexpression of epidermal growth factor receptor and cyclooxygenase-2 in carcinomas of the uterine cervix: a potential predictor of poor survival. Clin Cancer Res 2004, 10:1366-1374.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1366-1374
-
-
Kim, G.E.1
Kim, Y.B.2
Cho, N.H.3
-
71
-
-
22144439815
-
Cyclooxygenase-2 and prostaglandin signaling in cholangiocarcinoma
-
Wu T. Cyclooxygenase-2 and prostaglandin signaling in cholangiocarcinoma. Biochim Biophys Acta 2005, 1755:135-150.
-
(2005)
Biochim Biophys Acta
, vol.1755
, pp. 135-150
-
-
Wu, T.1
-
72
-
-
33748480133
-
Cyclooxygenases in hepatocellular carcinoma
-
Cervello M., Montalto G. Cyclooxygenases in hepatocellular carcinoma. World J Gastroenterol 2006, 12:5113-5121.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 5113-5121
-
-
Cervello, M.1
Montalto, G.2
-
73
-
-
0141562299
-
Lung cancer and cyclooxygenase-2
-
Castelao J.E., Bart R.D., DiPerna C.A., Sievers E.M., Bremner R.M. Lung cancer and cyclooxygenase-2. Ann Thorac Surg 2003, 76:1327-1335.
-
(2003)
Ann Thorac Surg
, vol.76
, pp. 1327-1335
-
-
Castelao, J.E.1
Bart, R.D.2
DiPerna, C.A.3
Sievers, E.M.4
Bremner, R.M.5
-
74
-
-
0033105360
-
Cyclooxygenase-2 expression is up-regulated in squamous cell carcinoma of the head and neck
-
Chan G., Boyle J.O., Yang E.K., et al. Cyclooxygenase-2 expression is up-regulated in squamous cell carcinoma of the head and neck. Cancer Res 1999, 59:991-994.
-
(1999)
Cancer Res
, vol.59
, pp. 991-994
-
-
Chan, G.1
Boyle, J.O.2
Yang, E.K.3
-
75
-
-
33646442342
-
Cyclooxygenase-1 and -2 expressions in the human thyroid gland
-
Lee H.M., Baek S.K., Kwon S.Y., et al. Cyclooxygenase-1 and -2 expressions in the human thyroid gland. Eur Arch Otorhinolaryngol 2006, 263:199-204.
-
(2006)
Eur Arch Otorhinolaryngol
, vol.263
, pp. 199-204
-
-
Lee, H.M.1
Baek, S.K.2
Kwon, S.Y.3
-
76
-
-
39049085637
-
Cyclooxygenase-2 (Cox-2) and blast cells of patients with acute leukemia
-
Vincent C., Donnard M., Bordessoule D., Turlure P., Trimoreau F., Denizot Y. Cyclooxygenase-2 (Cox-2) and blast cells of patients with acute leukemia. Leuk Res 2008, 32:671-673.
-
(2008)
Leuk Res
, vol.32
, pp. 671-673
-
-
Vincent, C.1
Donnard, M.2
Bordessoule, D.3
Turlure, P.4
Trimoreau, F.5
Denizot, Y.6
-
77
-
-
18644386378
-
Bone marrow cyclooxygenase-2 levels are elevated in chronic-phase chronic myeloid leukaemia and are associated with reduced survival
-
Giles F.J., Kantarjian H.M., Bekele B.N., et al. Bone marrow cyclooxygenase-2 levels are elevated in chronic-phase chronic myeloid leukaemia and are associated with reduced survival. Br J Haematol 2002, 119:38-45.
-
(2002)
Br J Haematol
, vol.119
, pp. 38-45
-
-
Giles, F.J.1
Kantarjian, H.M.2
Bekele, B.N.3
-
78
-
-
33750433938
-
Expression of cyclooxygenase-2 in Hodgkin's lymphoma: its role in cell proliferation and angiogenesis
-
Ohsawa M., Fukushima H., Ikura Y., et al. Expression of cyclooxygenase-2 in Hodgkin's lymphoma: its role in cell proliferation and angiogenesis. Leuk Lymphoma 2006, 47:1863-1871.
-
(2006)
Leuk Lymphoma
, vol.47
, pp. 1863-1871
-
-
Ohsawa, M.1
Fukushima, H.2
Ikura, Y.3
-
79
-
-
34247895800
-
Cyclooxygenase-2 expression in non-Hodgkin's lymphomas
-
Paydas S., Ergin M., Erdogan S., Seydaoglu G. Cyclooxygenase-2 expression in non-Hodgkin's lymphomas. Leuk Lymphoma 2007, 48:389-395.
-
(2007)
Leuk Lymphoma
, vol.48
, pp. 389-395
-
-
Paydas, S.1
Ergin, M.2
Erdogan, S.3
Seydaoglu, G.4
-
80
-
-
27644525342
-
Overexpression of cyclooxygenase-2 in multiple myeloma: association with reduced survival
-
Cetin M., Buyukberber S., Demir M., et al. Overexpression of cyclooxygenase-2 in multiple myeloma: association with reduced survival. Am J Hematol 2005, 80:169-173.
-
(2005)
Am J Hematol
, vol.80
, pp. 169-173
-
-
Cetin, M.1
Buyukberber, S.2
Demir, M.3
-
81
-
-
33745181682
-
Constitutive and activation-inducible cyclooxygenase-2 expression enhances survival of chronic lymphocytic leukemia B cells
-
Ryan E.P., Pollock S.J., Kaur K., et al. Constitutive and activation-inducible cyclooxygenase-2 expression enhances survival of chronic lymphocytic leukemia B cells. Clin Immunol 2006, 120:76-90.
-
(2006)
Clin Immunol
, vol.120
, pp. 76-90
-
-
Ryan, E.P.1
Pollock, S.J.2
Kaur, K.3
-
82
-
-
0035947586
-
Prostaglandin E2 increases growth and motility of colorectal carcinoma cells
-
Sheng H., Shao J., Washington M.K., DuBois R.N. Prostaglandin E2 increases growth and motility of colorectal carcinoma cells. J Biol Chem 2001, 276:18075-18081.
-
(2001)
J Biol Chem
, vol.276
, pp. 18075-18081
-
-
Sheng, H.1
Shao, J.2
Washington, M.K.3
DuBois, R.N.4
-
83
-
-
0031984810
-
Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells
-
Sheng H., Shao J., Morrow J.D., Beauchamp R.D., DuBois R.N. Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. Cancer Res 1998, 58:362-366.
-
(1998)
Cancer Res
, vol.58
, pp. 362-366
-
-
Sheng, H.1
Shao, J.2
Morrow, J.D.3
Beauchamp, R.D.4
DuBois, R.N.5
-
84
-
-
0003504049
-
Cyclooxygenase regulates angiogenesis induced by colon cancer cells
-
Tsujii M., Kawano S., Tsuji S., Sawaoka H., Hori M., DuBois R.N. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 1998, 93:705-716.
-
(1998)
Cell
, vol.93
, pp. 705-716
-
-
Tsujii, M.1
Kawano, S.2
Tsuji, S.3
Sawaoka, H.4
Hori, M.5
DuBois, R.N.6
-
85
-
-
0028803728
-
Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
-
Tsujii M., DuBois R.N. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 1995, 83:493-501.
-
(1995)
Cell
, vol.83
, pp. 493-501
-
-
Tsujii, M.1
DuBois, R.N.2
-
86
-
-
0030952695
-
Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential
-
Tsujii M., Kawano S., DuBois R.N. Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. Proc Natl Acad Sci USA 1997, 94:3336-3340.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3336-3340
-
-
Tsujii, M.1
Kawano, S.2
DuBois, R.N.3
-
87
-
-
23244437041
-
Cyclooxygenase 2 inhibition promotes IFN-gamma-dependent enhancement of antitumor responses
-
Sharma S., Zhu L., Yang S.C., et al. Cyclooxygenase 2 inhibition promotes IFN-gamma-dependent enhancement of antitumor responses. J Immunol 2005, 175:813-819.
-
(2005)
J Immunol
, vol.175
, pp. 813-819
-
-
Sharma, S.1
Zhu, L.2
Yang, S.C.3
-
88
-
-
23344445344
-
Cyclooxygenase-2-mediated DNA damage
-
Lee S.H., Williams M.V., Dubois R.N., Blair I.A. Cyclooxygenase-2-mediated DNA damage. J Biol Chem 2005, 280:28337-28346.
-
(2005)
J Biol Chem
, vol.280
, pp. 28337-28346
-
-
Lee, S.H.1
Williams, M.V.2
Dubois, R.N.3
Blair, I.A.4
-
89
-
-
0037041899
-
Prostaglandin E2 reinforces the activation of Ras signal pathway in lung adenocarcinoma cells via EP3
-
Yano T., Zissel G., Muller-Qernheim J., Shin S.J., Satoh H., Ichikawa T. Prostaglandin E2 reinforces the activation of Ras signal pathway in lung adenocarcinoma cells via EP3. FEBS Lett 2002, 518:154-158.
-
(2002)
FEBS Lett
, vol.518
, pp. 154-158
-
-
Yano, T.1
Zissel, G.2
Muller-Qernheim, J.3
Shin, S.J.4
Satoh, H.5
Ichikawa, T.6
-
90
-
-
66149120695
-
Cyclooxygenase inhibitors differentially modulate p73 isoforms in neuroblastoma
-
Lau L.M., Wolter J.K., Lau J.T., et al. Cyclooxygenase inhibitors differentially modulate p73 isoforms in neuroblastoma. Oncogene 2009, 28:2024-2033.
-
(2009)
Oncogene
, vol.28
, pp. 2024-2033
-
-
Lau, L.M.1
Wolter, J.K.2
Lau, J.T.3
-
91
-
-
62349138124
-
The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
-
Greenhough A., Smartt H.J.M., Moore A.E., et al. The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment. Carcinogenesis 2009, 30:377-386.
-
(2009)
Carcinogenesis
, vol.30
, pp. 377-386
-
-
Greenhough, A.1
Smartt, H.J.M.2
Moore, A.E.3
-
92
-
-
4944265244
-
Gene expression profiling of tumor-stromal interactions between pancreatic cancer cells and stromal fibroblasts
-
Sato N., Maehara N., Goggins M. Gene expression profiling of tumor-stromal interactions between pancreatic cancer cells and stromal fibroblasts. Cancer Res 2004, 64:6950-6956.
-
(2004)
Cancer Res
, vol.64
, pp. 6950-6956
-
-
Sato, N.1
Maehara, N.2
Goggins, M.3
-
93
-
-
27644549559
-
Infiltration of COX-2-expressing macrophages is a prerequisite for IL-1 beta-induced neovascularization and tumor growth
-
Nakao S., Kuwano T., Tsutsumi-Miyahara C., et al. Infiltration of COX-2-expressing macrophages is a prerequisite for IL-1 beta-induced neovascularization and tumor growth. J Clin Invest 2005, 115:2979-2991.
-
(2005)
J Clin Invest
, vol.115
, pp. 2979-2991
-
-
Nakao, S.1
Kuwano, T.2
Tsutsumi-Miyahara, C.3
-
94
-
-
77749304055
-
COX-2 and prostaglandin EP3/EP4 signaling regulate the tumor stromal proangiogenic microenvironment via CXCL12-CXCR4 chemokine systems
-
Katoh H., Hosono K., Ito Y., et al. COX-2 and prostaglandin EP3/EP4 signaling regulate the tumor stromal proangiogenic microenvironment via CXCL12-CXCR4 chemokine systems. Am J Pathol 2010, 176:1469-1483.
-
(2010)
Am J Pathol
, vol.176
, pp. 1469-1483
-
-
Katoh, H.1
Hosono, K.2
Ito, Y.3
-
95
-
-
62549099627
-
Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast
-
Hu M., Peluffo G., Chen H., Gelman R., Schnitt S., Polyak K. Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast. Proc Natl Acad Sci USA 2009, 106:3372-3377.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3372-3377
-
-
Hu, M.1
Peluffo, G.2
Chen, H.3
Gelman, R.4
Schnitt, S.5
Polyak, K.6
-
96
-
-
0037343236
-
Tumor cyclo-oxygenase-2-dependent suppression of dendritic cell function
-
Sharma S., Stolina M., Yang S.-C., et al. Tumor cyclo-oxygenase-2-dependent suppression of dendritic cell function. Clin Cancer Res 2003, 9:961-968.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 961-968
-
-
Sharma, S.1
Stolina, M.2
Yang, S.-C.3
-
97
-
-
20444464066
-
Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer
-
Sharma S., Yang S.-C., Zhu L., et al. Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer. Cancer Res 2005, 65:5211-5220.
-
(2005)
Cancer Res
, vol.65
, pp. 5211-5220
-
-
Sharma, S.1
Yang, S.-C.2
Zhu, L.3
-
98
-
-
0037310126
-
Regulation of cyclooxygenase-2 expression by the Wnt and ras pathways
-
Araki Y., Okamura S., Hussain S.P., et al. Regulation of cyclooxygenase-2 expression by the Wnt and ras pathways. Cancer Res 2003, 63:728-734.
-
(2003)
Cancer Res
, vol.63
, pp. 728-734
-
-
Araki, Y.1
Okamura, S.2
Hussain, S.P.3
-
99
-
-
0028982827
-
Transcriptional induction of prostaglandin G/H synthase-2 by basic fibroblast growth factor
-
Kawaguchi H., Pilbeam C.C., Gronowicz G., et al. Transcriptional induction of prostaglandin G/H synthase-2 by basic fibroblast growth factor. J Clin Invest 1995, 96:923-930.
-
(1995)
J Clin Invest
, vol.96
, pp. 923-930
-
-
Kawaguchi, H.1
Pilbeam, C.C.2
Gronowicz, G.3
-
100
-
-
0141693969
-
Expression of cyclooxygenase-2 and its relationship to p53 accumulation in ovarian adenocarcinomas
-
Shigemasa K., Tian X., Gu L., Shiroyama Y., Nagai N., Ohama K. Expression of cyclooxygenase-2 and its relationship to p53 accumulation in ovarian adenocarcinomas. Int J Oncol 2003, 22:99-105.
-
(2003)
Int J Oncol
, vol.22
, pp. 99-105
-
-
Shigemasa, K.1
Tian, X.2
Gu, L.3
Shiroyama, Y.4
Nagai, N.5
Ohama, K.6
-
101
-
-
77949724467
-
DNA damage drives an activin a-dependent induction of cyclooxygenase-2 in premalignant cells and lesions
-
Fordyce C., Fessenden T., Pickering C., et al. DNA damage drives an activin a-dependent induction of cyclooxygenase-2 in premalignant cells and lesions. Cancer Prev Res 2010, 3:190-201.
-
(2010)
Cancer Prev Res
, vol.3
, pp. 190-201
-
-
Fordyce, C.1
Fessenden, T.2
Pickering, C.3
-
102
-
-
74549160858
-
Identification of cyclooxygenase-2 as a major actor of the transcriptomic adaptation of endothelial and tumor cells to cyclic hypoxia: effect on angiogenesis and metastases
-
Daneau G., Boidot R., Martinive P., Feron O. Identification of cyclooxygenase-2 as a major actor of the transcriptomic adaptation of endothelial and tumor cells to cyclic hypoxia: effect on angiogenesis and metastases. Clin Cancer Res 2010, 16:410-419.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 410-419
-
-
Daneau, G.1
Boidot, R.2
Martinive, P.3
Feron, O.4
-
103
-
-
0141540687
-
Enhancing radiotherapy with cyclooxygenase-2 enzyme inhibitors: a rational advance?
-
Choy H., Milas L. Enhancing radiotherapy with cyclooxygenase-2 enzyme inhibitors: a rational advance?. J Natl Cancer Inst 2003, 95:1440-1452.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 1440-1452
-
-
Choy, H.1
Milas, L.2
-
104
-
-
0037083483
-
Increased cyclooxygenase-2 expression is associated with chemotherapy resistance and poor survival in cervical cancer patients
-
Ferrandina G., Lauriola L., Distefano M.G., et al. Increased cyclooxygenase-2 expression is associated with chemotherapy resistance and poor survival in cervical cancer patients. J Clin Oncol 2002, 973-998.
-
(2002)
J Clin Oncol
, pp. 973-998
-
-
Ferrandina, G.1
Lauriola, L.2
Distefano, M.G.3
-
105
-
-
0029904828
-
Cyclooxygenase-2 and its regulation in inflammation
-
Bakhle Y.S., Botting R.M. Cyclooxygenase-2 and its regulation in inflammation. Mediat Inflamm 1996, 5:305-323.
-
(1996)
Mediat Inflamm
, vol.5
, pp. 305-323
-
-
Bakhle, Y.S.1
Botting, R.M.2
-
106
-
-
0035990225
-
Cyclooxygenase-2 is overexpressed in chronic pancreatitis
-
Schlosser W., Schlosser S., Ramadani M., Gansauge F., Gansauge S., Beger H.-G. Cyclooxygenase-2 is overexpressed in chronic pancreatitis. Pancreas 2002, 25:26-30.
-
(2002)
Pancreas
, vol.25
, pp. 26-30
-
-
Schlosser, W.1
Schlosser, S.2
Ramadani, M.3
Gansauge, F.4
Gansauge, S.5
Beger, H.-G.6
-
107
-
-
33846019615
-
Association of COX-2 expression with corresponding active and chronic inflammatory reactions in Barrett's metaplasia and progression to cancer
-
Ling F.C., Baldus S.E., Khochfar J., et al. Association of COX-2 expression with corresponding active and chronic inflammatory reactions in Barrett's metaplasia and progression to cancer. Histopathology 2007, 50:203-209.
-
(2007)
Histopathology
, vol.50
, pp. 203-209
-
-
Ling, F.C.1
Baldus, S.E.2
Khochfar, J.3
-
108
-
-
0030875018
-
Expression of cyclooxygenase-2 mRNA in active inflammatory bowel disease
-
Hendel J., Nielsen O.H. Expression of cyclooxygenase-2 mRNA in active inflammatory bowel disease. Am J Gastroenterol 1997, 2:1170-1173.
-
(1997)
Am J Gastroenterol
, vol.2
, pp. 1170-1173
-
-
Hendel, J.1
Nielsen, O.H.2
-
109
-
-
4544243747
-
At the crossroads of inflammation and cancer
-
Clevers H. At the crossroads of inflammation and cancer. Cell 2004, 118:671-674.
-
(2004)
Cell
, vol.118
, pp. 671-674
-
-
Clevers, H.1
-
110
-
-
0035947709
-
Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice
-
Liu C.H., Chang S.H., Narko K., et al. Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice. J Biol Chem 2001, 276:18563-18569.
-
(2001)
J Biol Chem
, vol.276
, pp. 18563-18569
-
-
Liu, C.H.1
Chang, S.H.2
Narko, K.3
-
111
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell 2000, 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
112
-
-
0034282465
-
Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice
-
Chulada P.C., Thompson M.B., Mahler J.F., et al. Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice. Cancer Res 2000, 60:4705-4708.
-
(2000)
Cancer Res
, vol.60
, pp. 4705-4708
-
-
Chulada, P.C.1
Thompson, M.B.2
Mahler, J.F.3
-
113
-
-
0030606299
-
Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)
-
Oshima M., Dinchuk J.E., Kargman S.L., et al. Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell 1996, 87:803-809.
-
(1996)
Cell
, vol.87
, pp. 803-809
-
-
Oshima, M.1
Dinchuk, J.E.2
Kargman, S.L.3
-
114
-
-
1642503735
-
Histologically normal human mammary epithelia with silenced p16(INK4a) overexpress COX-2, promoting a premalignant program
-
Crawford Y.G., Gauthier M.L., Joubel A., et al. Histologically normal human mammary epithelia with silenced p16(INK4a) overexpress COX-2, promoting a premalignant program. Cancer Cell 2004, 5:263-273.
-
(2004)
Cancer Cell
, vol.5
, pp. 263-273
-
-
Crawford, Y.G.1
Gauthier, M.L.2
Joubel, A.3
-
115
-
-
48249102773
-
Progressive metaplastic and dysplastic changes in mouse pancreas induced by cyclooxygenase-2 overexpression
-
Colby J.K., Klein R.D., McArthur M.J., et al. Progressive metaplastic and dysplastic changes in mouse pancreas induced by cyclooxygenase-2 overexpression. Neoplasia (New York) 2008, 10:782-796.
-
(2008)
Neoplasia (New York)
, vol.10
, pp. 782-796
-
-
Colby, J.K.1
Klein, R.D.2
McArthur, M.J.3
-
116
-
-
16244374632
-
A COX-2 inhibitor prevents the esophageal inflammation-metaplasia-adenocarcinoma sequence in rats
-
Oyama K., Fujimura T., Ninomiya I., et al. A COX-2 inhibitor prevents the esophageal inflammation-metaplasia-adenocarcinoma sequence in rats. Carcinogenesis 2005, 26:565-570.
-
(2005)
Carcinogenesis
, vol.26
, pp. 565-570
-
-
Oyama, K.1
Fujimura, T.2
Ninomiya, I.3
-
117
-
-
0028017855
-
Induction of oesophageal and forestomach carcinomas in rats by reflux of duodenal contents
-
Miwa K., Segawa M., Takano Y., et al. Induction of oesophageal and forestomach carcinomas in rats by reflux of duodenal contents. Br J Cancer 1994, 70:185-189.
-
(1994)
Br J Cancer
, vol.70
, pp. 185-189
-
-
Miwa, K.1
Segawa, M.2
Takano, Y.3
-
118
-
-
0035211027
-
Duodenal reflux induces cyclooxygenase-2 in the esophageal mucosa of rats: evidence for involvement of bile acids
-
Zhang F., Altorki N.K., Wu Y.C., Soslow R.A., Subbaramaiah K., Dannenberg A.J. Duodenal reflux induces cyclooxygenase-2 in the esophageal mucosa of rats: evidence for involvement of bile acids. Gastroenterology 2001, 121:1391-1399.
-
(2001)
Gastroenterology
, vol.121
, pp. 1391-1399
-
-
Zhang, F.1
Altorki, N.K.2
Wu, Y.C.3
Soslow, R.A.4
Subbaramaiah, K.5
Dannenberg, A.J.6
-
119
-
-
0035045145
-
Cyclooxygenase-2 expression in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence
-
Morris C.D., Armstrong G.R., Bigley G., Green H., Attwood S.E. Cyclooxygenase-2 expression in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence. Am J Gastroenterol 2001, 96:990-996.
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 990-996
-
-
Morris, C.D.1
Armstrong, G.R.2
Bigley, G.3
Green, H.4
Attwood, S.E.5
-
120
-
-
4644318290
-
Roles of Helicobacter pylori infection and cyclooxygenase-2 expression in gastric carcinogenesis
-
Sun W.-H., Yu Q., Shen H., et al. Roles of Helicobacter pylori infection and cyclooxygenase-2 expression in gastric carcinogenesis. World J Gastroenterol 2004, 10:2809-2813.
-
(2004)
World J Gastroenterol
, vol.10
, pp. 2809-2813
-
-
Sun, W.-H.1
Yu, Q.2
Shen, H.3
-
121
-
-
0034495173
-
Cyclooxygenase-2 expression in Helicobacter pylori-associated premalignant and malignant gastric lesions
-
Sung J.J., Leung W.K., Go M.Y., et al. Cyclooxygenase-2 expression in Helicobacter pylori-associated premalignant and malignant gastric lesions. Am J Pathol 2000, 157:729-735.
-
(2000)
Am J Pathol
, vol.157
, pp. 729-735
-
-
Sung, J.J.1
Leung, W.K.2
Go, M.Y.3
-
122
-
-
0036117690
-
Gastric MALT-lymphoma, gastrin and cyclooxygenases
-
Konturek P.C., Konturek S.J., Pierzchalski P., et al. Gastric MALT-lymphoma, gastrin and cyclooxygenases. Acta Gastroenterol Belg 2002, 65:17-23.
-
(2002)
Acta Gastroenterol Belg
, vol.65
, pp. 17-23
-
-
Konturek, P.C.1
Konturek, S.J.2
Pierzchalski, P.3
-
123
-
-
77949806496
-
Prostaglandin E2 prevents Helicobacter-induced gastric preneoplasia and facilitates persistent infection in a mouse model
-
Toller I.M., Hitzler I., Sayi A., Mueller A. Prostaglandin E2 prevents Helicobacter-induced gastric preneoplasia and facilitates persistent infection in a mouse model. Gastroenterology 2010, 138:1455-1467.
-
(2010)
Gastroenterology
, vol.138
, pp. 1455-1467
-
-
Toller, I.M.1
Hitzler, I.2
Sayi, A.3
Mueller, A.4
-
124
-
-
0037126069
-
Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis
-
Muller-Decker K., Neufang G., Berger I., Neumann M., Marks F., Furstenberger G. Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis. Proc Natl Acad Sci USA 2002, 99:12483-124838.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12483-124838
-
-
Muller-Decker, K.1
Neufang, G.2
Berger, I.3
Neumann, M.4
Marks, F.5
Furstenberger, G.6
-
125
-
-
36849036243
-
The effect of cyclooxygenase-2 overexpression on skin carcinogenesis is context dependent
-
Rundhaug J.E., Pavone A., Kim E., Fischer S.M. The effect of cyclooxygenase-2 overexpression on skin carcinogenesis is context dependent. Mol Carcinog 2007, 46:981-992.
-
(2007)
Mol Carcinog
, vol.46
, pp. 981-992
-
-
Rundhaug, J.E.1
Pavone, A.2
Kim, E.3
Fischer, S.M.4
-
126
-
-
57349118495
-
Transgenic expression of cyclooxygenase-2 in mouse intestine epithelium is insufficient to initiate tumorigenesis but promotes tumor progression
-
Al-Salihi M.A., Terrece Pearman A., Doan T., et al. Transgenic expression of cyclooxygenase-2 in mouse intestine epithelium is insufficient to initiate tumorigenesis but promotes tumor progression. Cancer Lett 2009, 273:225-232.
-
(2009)
Cancer Lett
, vol.273
, pp. 225-232
-
-
Al-Salihi, M.A.1
Terrece Pearman, A.2
Doan, T.3
-
127
-
-
25144490062
-
Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands
-
Kohno H., Suzuki R., Sugie S., Tanaka T. Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands. BMC Cancer 2005, 5:46.
-
(2005)
BMC Cancer
, vol.5
, pp. 46
-
-
Kohno, H.1
Suzuki, R.2
Sugie, S.3
Tanaka, T.4
-
128
-
-
77950907803
-
Tumor formation in a mouse model of colitis- associated colon cancer does not require COX-1 or COX-2 expression
-
Ishikawa T., Herschman H.R. Tumor formation in a mouse model of colitis- associated colon cancer does not require COX-1 or COX-2 expression. Carcinogenesis 2010, 31:729-736.
-
(2010)
Carcinogenesis
, vol.31
, pp. 729-736
-
-
Ishikawa, T.1
Herschman, H.R.2
-
129
-
-
0029117472
-
Expression of cyclooxygenase-1 and -2 in human colorectal cancer
-
Sano H., Kawahito Y., Wilder R.L., et al. Expression of cyclooxygenase-1 and -2 in human colorectal cancer. Cancer Res 1995, 35:3785-3789.
-
(1995)
Cancer Res
, vol.35
, pp. 3785-3789
-
-
Sano, H.1
Kawahito, Y.2
Wilder, R.L.3
-
130
-
-
33644510747
-
Stimulation of cyclooxygenase-2 expression by bone-derived transforming growth factor-beta enhances bone metastases in breast cancer
-
Hiraga T., Myoui A., Choi M.E., Yoshikawa H., Yoneda T. Stimulation of cyclooxygenase-2 expression by bone-derived transforming growth factor-beta enhances bone metastases in breast cancer. Cancer Res 2006, 66:2067-2073.
-
(2006)
Cancer Res
, vol.66
, pp. 2067-2073
-
-
Hiraga, T.1
Myoui, A.2
Choi, M.E.3
Yoshikawa, H.4
Yoneda, T.5
-
131
-
-
0037089506
-
Selective cyclooxygenase (COX)-1 or COX-2 inhibitors control metastatic disease in a murine model of breast cancer
-
Kundu N., Fulton A.M. Selective cyclooxygenase (COX)-1 or COX-2 inhibitors control metastatic disease in a murine model of breast cancer. Cancer Res 2002, 62:2343-2346.
-
(2002)
Cancer Res
, vol.62
, pp. 2343-2346
-
-
Kundu, N.1
Fulton, A.M.2
-
132
-
-
0035849792
-
Multi-faceted analyses of a highly metastatic human lung cancer cell line NCI-H460-LNM35 suggest mimicry of inflammatory cells in metastasis
-
Kozaki K., Koshikawa K., Tatematsu Y., et al. Multi-faceted analyses of a highly metastatic human lung cancer cell line NCI-H460-LNM35 suggest mimicry of inflammatory cells in metastasis. Oncogene 2001, 20:4228-4234.
-
(2001)
Oncogene
, vol.20
, pp. 4228-4234
-
-
Kozaki, K.1
Koshikawa, K.2
Tatematsu, Y.3
-
133
-
-
15744397205
-
Expression and function of the nuclear factor of activated T cells in colon carcinoma cells: involvement in the regulation of cyclooxygenase-2
-
Duque J., Fresno M., Iniguez M.A. Expression and function of the nuclear factor of activated T cells in colon carcinoma cells: involvement in the regulation of cyclooxygenase-2. J Biol Chem 2005, 280:8686-8693.
-
(2005)
J Biol Chem
, vol.280
, pp. 8686-8693
-
-
Duque, J.1
Fresno, M.2
Iniguez, M.A.3
-
134
-
-
77954565039
-
Inflammation-mediated promotion of invasion and metastasis
-
Solinas G., Marchesi F., Garlanda C., Mantovani A., Allavena P. Inflammation-mediated promotion of invasion and metastasis. Cancer Metastasis Rev 2010, 29:243-248.
-
(2010)
Cancer Metastasis Rev
, vol.29
, pp. 243-248
-
-
Solinas, G.1
Marchesi, F.2
Garlanda, C.3
Mantovani, A.4
Allavena, P.5
-
135
-
-
56049089380
-
Cox-2 inactivates Smad signaling and enhances EMT stimulated by TGF-beta through a PGE2-dependent mechanisms
-
Neil J.R., Johnson K.M., Nemenoff R.A., Schiemann W.P. Cox-2 inactivates Smad signaling and enhances EMT stimulated by TGF-beta through a PGE2-dependent mechanisms. Carcinogenesis 2008, 29:2227-2235.
-
(2008)
Carcinogenesis
, vol.29
, pp. 2227-2235
-
-
Neil, J.R.1
Johnson, K.M.2
Nemenoff, R.A.3
Schiemann, W.P.4
-
136
-
-
33846264945
-
RhoA mediates cyclooxygenase-2 signaling to disrupt the formation of adherens junctions and increase cell motility
-
Chang Y.-W.E., Marlin J.W., Chance T.W., Jakobi R. RhoA mediates cyclooxygenase-2 signaling to disrupt the formation of adherens junctions and increase cell motility. Cancer Res 2006, 66:11700-11708.
-
(2006)
Cancer Res
, vol.66
, pp. 11700-11708
-
-
Chang, Y.-W.E.1
Marlin, J.W.2
Chance, T.W.3
Jakobi, R.4
-
137
-
-
33744925683
-
Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer
-
Dohadwala M., Yang S.-C., Luo J., et al. Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. Cancer Res 2006, 66:5338-5345.
-
(2006)
Cancer Res
, vol.66
, pp. 5338-5345
-
-
Dohadwala, M.1
Yang, S.-C.2
Luo, J.3
-
138
-
-
0036955336
-
The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression
-
Lara-Pezzi E., Gomez-Gaviro M.V., Galvez B.G., et al. The hepatitis B virus X protein promotes tumor cell invasion by inducing membrane-type matrix metalloproteinase-1 and cyclooxygenase-2 expression. J Clin Invest 2002, 110:1831-1838.
-
(2002)
J Clin Invest
, vol.110
, pp. 1831-1838
-
-
Lara-Pezzi, E.1
Gomez-Gaviro, M.V.2
Galvez, B.G.3
-
139
-
-
0034662627
-
Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases
-
Attiga F.A., Fernandez P.M., Weeraratna A.T., Manyak M.J., Patierno S.R. Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases. Cancer Res 2000, 60:4629-4637.
-
(2000)
Cancer Res
, vol.60
, pp. 4629-4637
-
-
Attiga, F.A.1
Fernandez, P.M.2
Weeraratna, A.T.3
Manyak, M.J.4
Patierno, S.R.5
-
140
-
-
15244360281
-
Association of cyclooxygenase-2 and matrix metalloproteinase-2 expression in human breast cancer
-
Sivula A., Talvensaari-Mattila A., Lundin J., et al. Association of cyclooxygenase-2 and matrix metalloproteinase-2 expression in human breast cancer. Breast Cancer Res Treat 2005, 89:215-220.
-
(2005)
Breast Cancer Res Treat
, vol.89
, pp. 215-220
-
-
Sivula, A.1
Talvensaari-Mattila, A.2
Lundin, J.3
-
141
-
-
0346037266
-
Hepatocyte growth factor inhibits anoikis by induction of activator protein 1-dependent cyclooxygenase-2. Implication in head and neck squamous cell carcinoma progression
-
Zeng Q., McCauley L.K., Wang C.-Y. Hepatocyte growth factor inhibits anoikis by induction of activator protein 1-dependent cyclooxygenase-2. Implication in head and neck squamous cell carcinoma progression. J Biol Chem 2002, 277:50137-50142.
-
(2002)
J Biol Chem
, vol.277
, pp. 50137-50142
-
-
Zeng, Q.1
McCauley, L.K.2
Wang, C.-Y.3
-
142
-
-
45549109399
-
Cyclooxygenase-2 up-regulates CCR7 via EP2/EP4 receptor signaling pathways to enhance lymphatic invasion of breast cancer cells
-
Pan M.-R., Hou M.-F., Chang H.-C., Hung W.-C. Cyclooxygenase-2 up-regulates CCR7 via EP2/EP4 receptor signaling pathways to enhance lymphatic invasion of breast cancer cells. J Biol Chem 2008, 283:11155-11163.
-
(2008)
J Biol Chem
, vol.283
, pp. 11155-11163
-
-
Pan, M.-R.1
Hou, M.-F.2
Chang, H.-C.3
Hung, W.-C.4
-
143
-
-
0036494318
-
Cyclooxygenase-2 activity altered the cell-surface carbohydrate antigens on colon cancer cells and enhanced liver metastasis
-
Kakiuchi Y., Tsuji S., Tsujii M., et al. Cyclooxygenase-2 activity altered the cell-surface carbohydrate antigens on colon cancer cells and enhanced liver metastasis. Cancer Res 2002, 62:1567-1572.
-
(2002)
Cancer Res
, vol.62
, pp. 1567-1572
-
-
Kakiuchi, Y.1
Tsuji, S.2
Tsujii, M.3
-
144
-
-
0033082201
-
Cyclooxygenase-2 overexpression enhances lymphatic invasion and metastasis in human gastric carcinoma
-
Murata H., Kawano S., Tsuji S., et al. Cyclooxygenase-2 overexpression enhances lymphatic invasion and metastasis in human gastric carcinoma. Am J Gastroenterol 1999, 94:451-455.
-
(1999)
Am J Gastroenterol
, vol.94
, pp. 451-455
-
-
Murata, H.1
Kawano, S.2
Tsuji, S.3
-
145
-
-
33846457870
-
Cancer statistics, 2007
-
Jemal A., Siegel R., Ward E., Murray T., Xu J., Thun M.J. Cancer statistics, 2007. CA Cancer J Clin 2007, 57:43-66.
-
(2007)
CA Cancer J Clin
, vol.57
, pp. 43-66
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Murray, T.4
Xu, J.5
Thun, M.J.6
-
146
-
-
1542343955
-
Role of p300 and PCAF in regulating cyclooxygenase-2 promoter activation by inflammatory mediators
-
Deng W.-G., Zhu Y., Wu K.K. Role of p300 and PCAF in regulating cyclooxygenase-2 promoter activation by inflammatory mediators. Blood 2004, 103:2135-2142.
-
(2004)
Blood
, vol.103
, pp. 2135-2142
-
-
Deng, W.-G.1
Zhu, Y.2
Wu, K.K.3
-
147
-
-
0032555484
-
Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway
-
Sheng H., Williams C.S., Shao J., Liang P., DuBois R.N., Beauchamp R.D. Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway. J Biol Chem 1998, 273:22120-22127.
-
(1998)
J Biol Chem
, vol.273
, pp. 22120-22127
-
-
Sheng, H.1
Williams, C.S.2
Shao, J.3
Liang, P.4
DuBois, R.N.5
Beauchamp, R.D.6
-
148
-
-
0033574630
-
Inhibition of cyclooxygenase-2 gene expression by p53
-
Subbaramaiah K., Altorki N., Chung W.J., Mestre J.R., Sampat A., Dannenberg A.J. Inhibition of cyclooxygenase-2 gene expression by p53. J Biol Chem 1999, 274:10911-10915.
-
(1999)
J Biol Chem
, vol.274
, pp. 10911-10915
-
-
Subbaramaiah, K.1
Altorki, N.2
Chung, W.J.3
Mestre, J.R.4
Sampat, A.5
Dannenberg, A.J.6
-
149
-
-
31544467810
-
Thioredoxin-1 modulates transcription of cyclooxygenase-2 via hypoxia-inducible factor-1alpha in non-small cell lung cancer
-
Csiki I., Yanagisawa K., Haruki N., et al. Thioredoxin-1 modulates transcription of cyclooxygenase-2 via hypoxia-inducible factor-1alpha in non-small cell lung cancer. Cancer Res 2006, 66:143-150.
-
(2006)
Cancer Res
, vol.66
, pp. 143-150
-
-
Csiki, I.1
Yanagisawa, K.2
Haruki, N.3
-
150
-
-
77649258068
-
Kaposi's sarcoma associated herpes virus (KSHV) induced COX-2: a key factor in latency, inflammation, angiogenesis, cell survival and invasion
-
Sharma-Walia N., Paul A.G., Bottero V., et al. Kaposi's sarcoma associated herpes virus (KSHV) induced COX-2: a key factor in latency, inflammation, angiogenesis, cell survival and invasion. PLoS Pathog 2010, 6:e1000777.
-
(2010)
PLoS Pathog
, vol.6
-
-
Sharma-Walia, N.1
Paul, A.G.2
Bottero, V.3
-
151
-
-
53349101676
-
Early upregulation of cyclooxygenase-2 in human papillomavirus type 16 and telomerase-induced immortalization of human esophageal epithelial cells
-
Zhuang Z.-H., Tsao S.-W., Deng W., et al. Early upregulation of cyclooxygenase-2 in human papillomavirus type 16 and telomerase-induced immortalization of human esophageal epithelial cells. J Gastroenterol Hepatol 2008, 23:1613-1620.
-
(2008)
J Gastroenterol Hepatol
, vol.23
, pp. 1613-1620
-
-
Zhuang, Z.-H.1
Tsao, S.-W.2
Deng, W.3
-
152
-
-
0032787558
-
HGF triggers activation of the COX-2 gene in rat gastric epithelial cells: action mediated through the ERK2 signaling pathway
-
Jones M.K., Sasaki E., Halter F., et al. HGF triggers activation of the COX-2 gene in rat gastric epithelial cells: action mediated through the ERK2 signaling pathway. FASEB J 1999, 13:2186-2194.
-
(1999)
FASEB J
, vol.13
, pp. 2186-2194
-
-
Jones, M.K.1
Sasaki, E.2
Halter, F.3
-
153
-
-
33745388145
-
Signalling networks regulating cyclooxygenase-2
-
Tsatsanis C., Androulidaki A., Venihaki M., Margioris A.N. Signalling networks regulating cyclooxygenase-2. Int J Biochem Cell Biol 2006, 38:1654-1661.
-
(2006)
Int J Biochem Cell Biol
, vol.38
, pp. 1654-1661
-
-
Tsatsanis, C.1
Androulidaki, A.2
Venihaki, M.3
Margioris, A.N.4
-
154
-
-
0029783253
-
Transcription of Cyclooxygenase-2 Is Enhanced in Transformed Mammary Epithelial Cells
-
Subbaramaiah K., Telang N., Ramonetti J.T., et al. Transcription of Cyclooxygenase-2 Is Enhanced in Transformed Mammary Epithelial Cells. Cancer Res 1996, 56:4424-4429.
-
(1996)
Cancer Res
, vol.56
, pp. 4424-4429
-
-
Subbaramaiah, K.1
Telang, N.2
Ramonetti, J.T.3
-
155
-
-
0028170074
-
V-src induction of the TIS10/PGS2 prostaglandin synthase gene is mediated by an ATF/CRE transcription response element
-
Xie W., Fletcher B.S., Andersen R.D., Herschman H.R. v-src induction of the TIS10/PGS2 prostaglandin synthase gene is mediated by an ATF/CRE transcription response element. Mol Cell Biol 1994, 14:6531-6539.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6531-6539
-
-
Xie, W.1
Fletcher, B.S.2
Andersen, R.D.3
Herschman, H.R.4
-
156
-
-
65549096389
-
Involvement of NF-kappa B and AP-1 in COX-2 upregulation by human papillomavirus 16 E5 oncoprotein
-
Kim S.-H., Oh J.-M., No J.-H., Bang Y.-J., Juhnn Y.-S., Song Y.-S. Involvement of NF-kappa B and AP-1 in COX-2 upregulation by human papillomavirus 16 E5 oncoprotein. Carcinogenesis 2009, 30:753-757.
-
(2009)
Carcinogenesis
, vol.30
, pp. 753-757
-
-
Kim, S.-H.1
Oh, J.-M.2
No, J.-H.3
Bang, Y.-J.4
Juhnn, Y.-S.5
Song, Y.-S.6
-
157
-
-
33744948986
-
NFAT induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2
-
Yiu G.K., Toker A. NFAT induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2. J Biol Chem 2006, 281:12210-12217.
-
(2006)
J Biol Chem
, vol.281
, pp. 12210-12217
-
-
Yiu, G.K.1
Toker, A.2
-
158
-
-
0037166271
-
Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: evidence for involvement of AP-1 and PEA3
-
Subbaramaiah K., Norton L., Gerald W., Dannenberg A.J. Cyclooxygenase-2 is overexpressed in HER-2/neu-positive breast cancer: evidence for involvement of AP-1 and PEA3. J Biol Chem 2002, 277:18649-18657.
-
(2002)
J Biol Chem
, vol.277
, pp. 18649-18657
-
-
Subbaramaiah, K.1
Norton, L.2
Gerald, W.3
Dannenberg, A.J.4
-
159
-
-
4143150641
-
Transcriptional regulation of cyclooxygenase-2 gene in pancreatic beta-cells
-
Yang F., Bleich D. Transcriptional regulation of cyclooxygenase-2 gene in pancreatic beta-cells. J Biol Chem 2004, 279:35403-35411.
-
(2004)
J Biol Chem
, vol.279
, pp. 35403-35411
-
-
Yang, F.1
Bleich, D.2
-
160
-
-
23944517220
-
The aryl hydrocarbon receptor is a regulator of cigarette smoke induction of the cyclooxygenase and prostaglandin pathways in human lung fibroblasts
-
Martey C.A., Baglole C.J., Gasiewicz T.A., Sime P.J., Phipps R.P. The aryl hydrocarbon receptor is a regulator of cigarette smoke induction of the cyclooxygenase and prostaglandin pathways in human lung fibroblasts. Am J Physiol Lung Cell Mol Physiol 2005, 289:L391-L399.
-
(2005)
Am J Physiol Lung Cell Mol Physiol
, vol.289
-
-
Martey, C.A.1
Baglole, C.J.2
Gasiewicz, T.A.3
Sime, P.J.4
Phipps, R.P.5
-
161
-
-
0029898467
-
Regulation of prostaglandin endoperoxide H synthase-2 expression by 2, 3, 7, 8,-tetrachlorodibenzo-p-dioxin
-
Kraemer S.A., Arthur K.A., Denison M.S., Smith W.L., DeWitt D.L. Regulation of prostaglandin endoperoxide H synthase-2 expression by 2, 3, 7, 8,-tetrachlorodibenzo-p-dioxin. Arch Biochem Biophys 1996, 330:319-328.
-
(1996)
Arch Biochem Biophys
, vol.330
, pp. 319-328
-
-
Kraemer, S.A.1
Arthur, K.A.2
Denison, M.S.3
Smith, W.L.4
DeWitt, D.L.5
-
162
-
-
33746123520
-
Direct transcriptional up-regulation of cyclooxygenase-2 by hypoxia-inducible factor (HIF)-1 promotes colorectal tumor cell survival and enhances HIF-1 transcriptional activity during hypoxia
-
Kaidi A., Qualtrough D., Williams A.C., Paraskeva C. Direct transcriptional up-regulation of cyclooxygenase-2 by hypoxia-inducible factor (HIF)-1 promotes colorectal tumor cell survival and enhances HIF-1 transcriptional activity during hypoxia. Cancer Res 2006, 66:6683-6691.
-
(2006)
Cancer Res
, vol.66
, pp. 6683-6691
-
-
Kaidi, A.1
Qualtrough, D.2
Williams, A.C.3
Paraskeva, C.4
-
163
-
-
0034736007
-
Cyclooxygenase-2 expression in lipopolysaccharide-stimulated human monocytes is modulated by cyclic AMP, prostaglandin E(2), and nonsteroidal anti-inflammatory drugs
-
Hinz B., Brune K., Pahl A. Cyclooxygenase-2 expression in lipopolysaccharide-stimulated human monocytes is modulated by cyclic AMP, prostaglandin E(2), and nonsteroidal anti-inflammatory drugs. Biochem Biophys Res Commun 2000, 278:790-796.
-
(2000)
Biochem Biophys Res Commun
, vol.278
, pp. 790-796
-
-
Hinz, B.1
Brune, K.2
Pahl, A.3
-
164
-
-
0033119190
-
Transcriptional activation of cyclooxygenase-2 in Wnt-1-transformed mouse mammary epithelial cells
-
Howe L.R., Subbaramaiah K., Chung W.J., Dannenberg A.J., Brown A.M. Transcriptional activation of cyclooxygenase-2 in Wnt-1-transformed mouse mammary epithelial cells. Cancer Res 1999, 59:1572-1577.
-
(1999)
Cancer Res
, vol.59
, pp. 1572-1577
-
-
Howe, L.R.1
Subbaramaiah, K.2
Chung, W.J.3
Dannenberg, A.J.4
Brown, A.M.5
-
165
-
-
0030949463
-
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
-
Korinek
-
Morin P.J., Sparks A.B., Korinek, et al. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 1997, 275:1787-1790.
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
-
166
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler K.W., Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996, 87:159-170.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
167
-
-
0019318994
-
DNA methylation and gene function
-
Razin A., Riggs A.D. DNA methylation and gene function. Science 1980, 210:604-610.
-
(1980)
Science
, vol.210
, pp. 604-610
-
-
Razin, A.1
Riggs, A.D.2
-
169
-
-
0035360797
-
Transcriptional silencing of cyclooxygenase-2 by hyper-methylation of the 5' CpG island in human gastric carcinoma cells
-
Song S.H., Jong H.S., Choi H.H., et al. Transcriptional silencing of cyclooxygenase-2 by hyper-methylation of the 5' CpG island in human gastric carcinoma cells. Cancer Res 2001, 61:4628-4635.
-
(2001)
Cancer Res
, vol.61
, pp. 4628-4635
-
-
Song, S.H.1
Jong, H.S.2
Choi, H.H.3
-
170
-
-
0035866790
-
Promoter methylation regulates Helicobacter pylori-stimulated cyclooxygenase-2 expression in gastric epithelial cells
-
Akhtar M., Cheng Y., Magno R.M., et al. Promoter methylation regulates Helicobacter pylori-stimulated cyclooxygenase-2 expression in gastric epithelial cells. Cancer Res 2001, 61:2399-2403.
-
(2001)
Cancer Res
, vol.61
, pp. 2399-2403
-
-
Akhtar, M.1
Cheng, Y.2
Magno, R.M.3
-
171
-
-
0029809863
-
Down-regulation of cytokine-induced cyclo-oxygenase-2 transcript isoforms by dexamethasone: evidence for post-transcriptional regulation
-
Ristimaki A., Narko K., Hla T. Down-regulation of cytokine-induced cyclo-oxygenase-2 transcript isoforms by dexamethasone: evidence for post-transcriptional regulation. Biochem J 1996, 318:325-331.
-
(1996)
Biochem J
, vol.318
, pp. 325-331
-
-
Ristimaki, A.1
Narko, K.2
Hla, T.3
-
172
-
-
0034697027
-
Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3'-untranslated region
-
Dixon D.A., Kaplan C.D., McIntyre T.M., Zimmerman G.A., Prescott S.M. Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3'-untranslated region. J Biol Chem 2000, 275:11750-11757.
-
(2000)
J Biol Chem
, vol.275
, pp. 11750-11757
-
-
Dixon, D.A.1
Kaplan, C.D.2
McIntyre, T.M.3
Zimmerman, G.A.4
Prescott, S.M.5
-
173
-
-
0035933736
-
The 3'-untranslated region of murine cyclooxygenase-2 contains multiple regulatory elements that alter message stability and translational efficiency
-
Cok S.J., Morrison A.R. The 3'-untranslated region of murine cyclooxygenase-2 contains multiple regulatory elements that alter message stability and translational efficiency. J Biol Chem 2001, 276:23179-23185.
-
(2001)
J Biol Chem
, vol.276
, pp. 23179-23185
-
-
Cok, S.J.1
Morrison, A.R.2
-
174
-
-
0029873536
-
Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein
-
Ma W.J., Cheng S., Campbell C., Wright A., Furneaux H. Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein. J Biol Chem 1996, 271:8144-8151.
-
(1996)
J Biol Chem
, vol.271
, pp. 8144-8151
-
-
Ma, W.J.1
Cheng, S.2
Campbell, C.3
Wright, A.4
Furneaux, H.5
-
175
-
-
0035213198
-
Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells
-
Dixon D.A., Tolley N.D., King P.H., et al. Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells. J Clin Invest 2001, 108:1657-1665.
-
(2001)
J Clin Invest
, vol.108
, pp. 1657-1665
-
-
Dixon, D.A.1
Tolley, N.D.2
King, P.H.3
-
176
-
-
9144266290
-
Overexpression of the embryonic-lethal abnormal vision-like protein HuR in ovarian carcinoma is a prognostic factor and is associated with increased cyclooxygenase 2 expression
-
Denkert C., Weichert W., Pest S., et al. Overexpression of the embryonic-lethal abnormal vision-like protein HuR in ovarian carcinoma is a prognostic factor and is associated with increased cyclooxygenase 2 expression. Cancer Res 2004, 64:189-195.
-
(2004)
Cancer Res
, vol.64
, pp. 189-195
-
-
Denkert, C.1
Weichert, W.2
Pest, S.3
-
177
-
-
34250889456
-
Expression of HuR is associated with increased cyclooxygenase-2 expression in uterine cervical carcinoma
-
Lim S.-J., Kim H.J., Kim J.Y., Park K., Lee C.-M. Expression of HuR is associated with increased cyclooxygenase-2 expression in uterine cervical carcinoma. Int J Gynecol Pathol 2007, 26:229-234.
-
(2007)
Int J Gynecol Pathol
, vol.26
, pp. 229-234
-
-
Lim, S.-J.1
Kim, H.J.2
Kim, J.Y.3
Park, K.4
Lee, C.-M.5
-
178
-
-
33750993498
-
Beta-catenin stabilizes cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3'-UTR
-
Lee H.K., Jeong S. Beta-catenin stabilizes cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3'-UTR. Nucleic Acids Res 2006, 34:5705-5714.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 5705-5714
-
-
Lee, H.K.1
Jeong, S.2
-
179
-
-
72149102129
-
Regulation of transforming growth factor-beta-dependent cyclooxygenase-2 expression in fibroblasts
-
Matsumura T., Suzuki T., Aizawa K., et al. Regulation of transforming growth factor-beta-dependent cyclooxygenase-2 expression in fibroblasts. J Biol Chem 2009, 284:35861-35871.
-
(2009)
J Biol Chem
, vol.284
, pp. 35861-35871
-
-
Matsumura, T.1
Suzuki, T.2
Aizawa, K.3
-
180
-
-
0041622806
-
Regulation of cyclooxygenase-2 expression by the translational silencer TIA-1
-
Dixon D.A., Balch G.C., Kedersha N., et al. Regulation of cyclooxygenase-2 expression by the translational silencer TIA-1. J Exp Med 2003, 198:475-481.
-
(2003)
J Exp Med
, vol.198
, pp. 475-481
-
-
Dixon, D.A.1
Balch, G.C.2
Kedersha, N.3
-
181
-
-
77953629046
-
Regulation of mRNA translation and stability by microRNAs
-
Fabian M.R., Sonenberg N., Filipowicz W. Regulation of mRNA translation and stability by microRNAs. Annu Rev Biochem 2010, 79:351-379.
-
(2010)
Annu Rev Biochem
, vol.79
, pp. 351-379
-
-
Fabian, M.R.1
Sonenberg, N.2
Filipowicz, W.3
-
182
-
-
73349125465
-
MicroRNAs in cancer: small molecules with a huge impact
-
Iorio M.V., Croce C.M. MicroRNAs in cancer: small molecules with a huge impact. J Clin Oncol 2009, 27:5848-5856.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5848-5856
-
-
Iorio, M.V.1
Croce, C.M.2
-
183
-
-
35448990125
-
MicroRNA regulation of cyclooxygenase-2 during embryo implantation
-
Chakrabarty A., Tranguch S., Daikoku T., Jensen K., Furneaux H., Dey S.K. MicroRNA regulation of cyclooxygenase-2 during embryo implantation. Proc Natl Acad Sci USA 2007, 104:15144-15149.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15144-15149
-
-
Chakrabarty, A.1
Tranguch, S.2
Daikoku, T.3
Jensen, K.4
Furneaux, H.5
Dey, S.K.6
-
184
-
-
64049086575
-
MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells
-
Strillacci A., Griffoni C., Sansone P., et al. MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells. Exp Cell Res 2009, 315:1439-1447.
-
(2009)
Exp Cell Res
, vol.315
, pp. 1439-1447
-
-
Strillacci, A.1
Griffoni, C.2
Sansone, P.3
-
185
-
-
43749094995
-
Two distinct pathways for cyclooxygenase-2 protein degradation
-
Mbonye U.R., Yuan C., Harris C.E., et al. Two distinct pathways for cyclooxygenase-2 protein degradation. J Biol Chem 2008, 283:8611-8623.
-
(2008)
J Biol Chem
, vol.283
, pp. 8611-8623
-
-
Mbonye, U.R.1
Yuan, C.2
Harris, C.E.3
-
186
-
-
71449089782
-
Two pathways for cyclooxygenase-2 protein degradation in vivo
-
Wada M., Saunders T.L., Morrow J., et al. Two pathways for cyclooxygenase-2 protein degradation in vivo. J Biol Chem 2009, 284:30742-30753.
-
(2009)
J Biol Chem
, vol.284
, pp. 30742-30753
-
-
Wada, M.1
Saunders, T.L.2
Morrow, J.3
-
187
-
-
74949124651
-
Caveolin-1 facilitates cyclooxygenase-2 protein degradation
-
Chen S.-F., Liou J.-Y., Huang T.-Y., et al. Caveolin-1 facilitates cyclooxygenase-2 protein degradation. J Cell Biochem 2010, 109:356-362.
-
(2010)
J Cell Biochem
, vol.109
, pp. 356-362
-
-
Chen, S.-F.1
Liou, J.-Y.2
Huang, T.-Y.3
-
188
-
-
0035986172
-
The alteration of prostaglandin E2 levels in patients with brain tumors before and after tumor removal
-
Loh J.-K., Hwang S.-L., Lieu A.-S., Huang T.-Y., Howng S.-L. The alteration of prostaglandin E2 levels in patients with brain tumors before and after tumor removal. J Neurooncol 2002, 57:147-150.
-
(2002)
J Neurooncol
, vol.57
, pp. 147-150
-
-
Loh, J.-K.1
Hwang, S.-L.2
Lieu, A.-S.3
Huang, T.-Y.4
Howng, S.-L.5
-
189
-
-
0027724464
-
Elevated plasma prostaglandin E2 levels found in 14 patients undergoing autologous bone marrow or stem cell transplantation
-
Cayeux S.J., Beverley P.C., Schulz R., Dorken B. Elevated plasma prostaglandin E2 levels found in 14 patients undergoing autologous bone marrow or stem cell transplantation. Bone Marrow Transplant 1993, 12:603-608.
-
(1993)
Bone Marrow Transplant
, vol.12
, pp. 603-608
-
-
Cayeux, S.J.1
Beverley, P.C.2
Schulz, R.3
Dorken, B.4
-
190
-
-
0027371123
-
Altered eicosanoid levels in human colon cancer
-
Rigas B., Goldman I.S., Levine L. Altered eicosanoid levels in human colon cancer. J Lab Clin Med 1993, 122:518-523.
-
(1993)
J Lab Clin Med
, vol.122
, pp. 518-523
-
-
Rigas, B.1
Goldman, I.S.2
Levine, L.3
-
191
-
-
0018744517
-
Prostaglandin synthetase and prostaglandin E2 levels in human breast carcinoma
-
Kibbey W.E., Bronn D.G., Minton J.P. Prostaglandin synthetase and prostaglandin E2 levels in human breast carcinoma. Prostaglandins Med 1979, 2:133-139.
-
(1979)
Prostaglandins Med
, vol.2
, pp. 133-139
-
-
Kibbey, W.E.1
Bronn, D.G.2
Minton, J.P.3
-
192
-
-
0034692689
-
Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2
-
Murakami M., Naraba H., Tanioka T., et al. Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2. J Biol Chem 2000, 275:32783-32792.
-
(2000)
J Biol Chem
, vol.275
, pp. 32783-32792
-
-
Murakami, M.1
Naraba, H.2
Tanioka, T.3
-
193
-
-
13544268334
-
15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer
-
Backlund M.G., Mann J.R., Holla V.R., et al. 15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer. J Biol Chem 2005, 280:3217-3223.
-
(2005)
J Biol Chem
, vol.280
, pp. 3217-3223
-
-
Backlund, M.G.1
Mann, J.R.2
Holla, V.R.3
-
194
-
-
13444269594
-
NAD+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer
-
Ding Y., Tong M., Liu S., Moscow J.A., Tai H.-H. NAD+-linked 15-hydroxyprostaglandin dehydrogenase (15-PGDH) behaves as a tumor suppressor in lung cancer. Carcinogenesis 2005, 26:65-72.
-
(2005)
Carcinogenesis
, vol.26
, pp. 65-72
-
-
Ding, Y.1
Tong, M.2
Liu, S.3
Moscow, J.A.4
Tai, H.-H.5
-
195
-
-
33748295848
-
Microsomal prostaglandin E synthase-1 regulates human glioma cell growth via prostaglandin E(2)-dependent activation of type II protein kinase A
-
Payner T., Leaver H.A., Knapp B., et al. Microsomal prostaglandin E synthase-1 regulates human glioma cell growth via prostaglandin E(2)-dependent activation of type II protein kinase A. Mol Cancer Ther 2006, 5:1817-1826.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1817-1826
-
-
Payner, T.1
Leaver, H.A.2
Knapp, B.3
-
196
-
-
34249729416
-
Prostaglandin E receptors
-
Sugimoto Y., Narumiya S. Prostaglandin E receptors. J Biol Chem 2007, 282:11613-11617.
-
(2007)
J Biol Chem
, vol.282
, pp. 11613-11617
-
-
Sugimoto, Y.1
Narumiya, S.2
-
197
-
-
0036006453
-
Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy
-
Pai R., Soreghan B., Szabo I.L., Pavelka M., Baatar D., Tarnawski A.S. Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy. Nat Med 2002, 8:289-293.
-
(2002)
Nat Med
, vol.8
, pp. 289-293
-
-
Pai, R.1
Soreghan, B.2
Szabo, I.L.3
Pavelka, M.4
Baatar, D.5
Tarnawski, A.S.6
-
198
-
-
33644898889
-
Prostaglandin E2 receptor EP1 transactivates EGFR/MET receptor tyrosine kinases and enhances invasiveness in human hepatocellular carcinoma cells
-
Han C., Michalopoulos G.K., Wu T. Prostaglandin E2 receptor EP1 transactivates EGFR/MET receptor tyrosine kinases and enhances invasiveness in human hepatocellular carcinoma cells. J Cell Physiol 2006, 207:261-270.
-
(2006)
J Cell Physiol
, vol.207
, pp. 261-270
-
-
Han, C.1
Michalopoulos, G.K.2
Wu, T.3
-
199
-
-
0034796261
-
Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice
-
Sonoshita M., Takaku K., Sasaki N., et al. Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice. Nat Med 2001, 7:1048-1051.
-
(2001)
Nat Med
, vol.7
, pp. 1048-1051
-
-
Sonoshita, M.1
Takaku, K.2
Sasaki, N.3
-
200
-
-
0036142927
-
Involvement of prostaglandin E receptor subtype EP4 in colon carcinogenesis
-
Mutoh M., Watanabe K., Kitamura T., et al. Involvement of prostaglandin E receptor subtype EP4 in colon carcinogenesis. Cancer Res 2002, 62:28-32.
-
(2002)
Cancer Res
, vol.62
, pp. 28-32
-
-
Mutoh, M.1
Watanabe, K.2
Kitamura, T.3
-
201
-
-
13844298698
-
Prostaglandin E receptor subtype EP1 deficiency inhibits colon cancer development
-
Kawamori T., Kitamura T., Watanabe K., et al. Prostaglandin E receptor subtype EP1 deficiency inhibits colon cancer development. Carcinogenesis 2005, 26:353-357.
-
(2005)
Carcinogenesis
, vol.26
, pp. 353-357
-
-
Kawamori, T.1
Kitamura, T.2
Watanabe, K.3
-
202
-
-
33646348742
-
Prostaglandin E2 regulates the nuclear receptor NR4A2 in colorectal cancer
-
Holla V.R., Mann J.R., Shi Q., DuBois R.N. Prostaglandin E2 regulates the nuclear receptor NR4A2 in colorectal cancer. J Biol Chem 2006, 281:2676-2682.
-
(2006)
J Biol Chem
, vol.281
, pp. 2676-2682
-
-
Holla, V.R.1
Mann, J.R.2
Shi, Q.3
DuBois, R.N.4
-
203
-
-
62849127105
-
PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer
-
Ghosh M., Ai Y., Narko K., Wang Z., Peters J.M., Hla T. PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer. Prostaglandins Other Lipid Mediat 2009, 88:97-100.
-
(2009)
Prostaglandins Other Lipid Mediat
, vol.88
, pp. 97-100
-
-
Ghosh, M.1
Ai, Y.2
Narko, K.3
Wang, Z.4
Peters, J.M.5
Hla, T.6
-
204
-
-
50349092829
-
Multiple signaling pathways are responsible for prostaglandin E2-induced murine keratinocyte proliferation
-
Ansari K.M., Rundhaug J.E., Fischer S.M. Multiple signaling pathways are responsible for prostaglandin E2-induced murine keratinocyte proliferation. Mol Cancer Res 2008, 6:1003-1016.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 1003-1016
-
-
Ansari, K.M.1
Rundhaug, J.E.2
Fischer, S.M.3
-
205
-
-
3142782285
-
Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation
-
Pozzi A., Yan X., Macias-Perez I., et al. Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation. J Biol Chem 2004, 279:29797-29804.
-
(2004)
J Biol Chem
, vol.279
, pp. 29797-29804
-
-
Pozzi, A.1
Yan, X.2
Macias-Perez, I.3
-
206
-
-
16444385003
-
Prostaglandin E2 enhances intestinal adenoma growth via activation of the Ras-mitogen-activated protein kinase cascade
-
Wang D., Buchanan F.G., Wang H., Dey S.K., DuBois R.N. Prostaglandin E2 enhances intestinal adenoma growth via activation of the Ras-mitogen-activated protein kinase cascade. Cancer Res 2005, 65:1822-1829.
-
(2005)
Cancer Res
, vol.65
, pp. 1822-1829
-
-
Wang, D.1
Buchanan, F.G.2
Wang, H.3
Dey, S.K.4
DuBois, R.N.5
-
207
-
-
34547758527
-
EP2 prostanoid receptor promotes squamous cell carcinoma growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathways
-
Donnini S., Finetti F., Solito R., et al. EP2 prostanoid receptor promotes squamous cell carcinoma growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathways. FASEB J 2007, 21:2418-2430.
-
(2007)
FASEB J
, vol.21
, pp. 2418-2430
-
-
Donnini, S.1
Finetti, F.2
Solito, R.3
-
208
-
-
19644379770
-
The Prostaglandin E2 receptor EP2 is required for cyclooxygenase 2-mediated mammary hyperplasia
-
Chang S.-H., Ai Y., Breyer R.M., Lane T.F., Hla T. The Prostaglandin E2 receptor EP2 is required for cyclooxygenase 2-mediated mammary hyperplasia. Cancer Res 2005, 65:4496-4499.
-
(2005)
Cancer Res
, vol.65
, pp. 4496-4499
-
-
Chang, S.-H.1
Ai, Y.2
Breyer, R.M.3
Lane, T.F.4
Hla, T.5
-
209
-
-
1842790624
-
Prostaglandin E2 synergistically enhances receptor tyrosine kinase-dependent signaling system in colon cancer cells
-
Shao J., Evers B.M., Sheng H. Prostaglandin E2 synergistically enhances receptor tyrosine kinase-dependent signaling system in colon cancer cells. J Biol Chem 2004, 279:14287-14293.
-
(2004)
J Biol Chem
, vol.279
, pp. 14287-14293
-
-
Shao, J.1
Evers, B.M.2
Sheng, H.3
-
210
-
-
22244467085
-
Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner
-
Krysan K., Reckamp K.L., Dalwadi H., et al. Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner. Cancer Res 2005, 65:6275-6281.
-
(2005)
Cancer Res
, vol.65
, pp. 6275-6281
-
-
Krysan, K.1
Reckamp, K.L.2
Dalwadi, H.3
-
211
-
-
28544444039
-
Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis
-
Castellone M.D., Teramoto H., Williams B.O., Druey K.M., Gutkind J.S. Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis. Science 2005, 310:1504-1510.
-
(2005)
Science
, vol.310
, pp. 1504-1510
-
-
Castellone, M.D.1
Teramoto, H.2
Williams, B.O.3
Druey, K.M.4
Gutkind, J.S.5
-
212
-
-
34250883337
-
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis
-
North T.E., Goessling W., Walkley C.R., et al. Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature 2007, 447:1007-1011.
-
(2007)
Nature
, vol.447
, pp. 1007-1011
-
-
North, T.E.1
Goessling, W.2
Walkley, C.R.3
-
213
-
-
74849102911
-
Prostaglandin E2 activates cAMP response element-binding protein in glioma cells via a signaling pathway involving PKA-dependent inhibition of ERK
-
Bidwell P., Joh K., Leaver H.A., Rizzo M.T. Prostaglandin E2 activates cAMP response element-binding protein in glioma cells via a signaling pathway involving PKA-dependent inhibition of ERK. Prostaglandins Other Lipid Mediat 2010, 91:18-29.
-
(2010)
Prostaglandins Other Lipid Mediat
, vol.91
, pp. 18-29
-
-
Bidwell, P.1
Joh, K.2
Leaver, H.A.3
Rizzo, M.T.4
-
214
-
-
42649118106
-
Human mesenchymal stem cell proliferation is regulated by PGE2 through differential activation of cAMP-dependent protein kinase isoforms
-
Kleiveland C.R., Kassem M., Lea T. Human mesenchymal stem cell proliferation is regulated by PGE2 through differential activation of cAMP-dependent protein kinase isoforms. Exp Cell Res 2008, 314:1831-1838.
-
(2008)
Exp Cell Res
, vol.314
, pp. 1831-1838
-
-
Kleiveland, C.R.1
Kassem, M.2
Lea, T.3
-
215
-
-
45549086404
-
Mouse EP3 alpha, beta, and gamma receptor variants reduce tumor cell proliferation and tumorigenesis in vivo
-
Macias-Perez I.M., Zent R., Carmosino M., et al. Mouse EP3 alpha, beta, and gamma receptor variants reduce tumor cell proliferation and tumorigenesis in vivo. J Biol Chem 2008, 283:12538-12545.
-
(2008)
J Biol Chem
, vol.283
, pp. 12538-12545
-
-
Macias-Perez, I.M.1
Zent, R.2
Carmosino, M.3
-
216
-
-
0038489501
-
Potential involvement of the cyclooxygenase-2 pathway in the regulation of tumor-associated angiogenesis and growth in pancreatic cancer
-
Chu J., Lloyd F.L., Trifan O.C., Knapp B., Rizzo M.T. Potential involvement of the cyclooxygenase-2 pathway in the regulation of tumor-associated angiogenesis and growth in pancreatic cancer. Mol Cancer Ther 2003, 2:1-7.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 1-7
-
-
Chu, J.1
Lloyd, F.L.2
Trifan, O.C.3
Knapp, B.4
Rizzo, M.T.5
-
217
-
-
0034791297
-
NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis
-
Dormond O., Foletti A., Paroz C., Ruegg C. NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis. Nat Med 2001, 7:1041-1047.
-
(2001)
Nat Med
, vol.7
, pp. 1041-1047
-
-
Dormond, O.1
Foletti, A.2
Paroz, C.3
Ruegg, C.4
-
218
-
-
38349183605
-
Prostaglandin E2 regulates angiogenesis via activation of fibroblast growth factor receptor-1
-
Finetti F., Solito R., Morbidelli L., Giachetti A., Ziche M., Donnini S. Prostaglandin E2 regulates angiogenesis via activation of fibroblast growth factor receptor-1. J Biol Chem 2008, 283:2139-2146.
-
(2008)
J Biol Chem
, vol.283
, pp. 2139-2146
-
-
Finetti, F.1
Solito, R.2
Morbidelli, L.3
Giachetti, A.4
Ziche, M.5
Donnini, S.6
-
219
-
-
54249155141
-
Prostaglandin E2 regulates tumor angiogenesis in prostate cancer
-
Jain S., Chakraborty G., Raja R., Kale S., Kundu G.C. Prostaglandin E2 regulates tumor angiogenesis in prostate cancer. Cancer Res 2008, 68:7750-7759.
-
(2008)
Cancer Res
, vol.68
, pp. 7750-7759
-
-
Jain, S.1
Chakraborty, G.2
Raja, R.3
Kale, S.4
Kundu, G.C.5
-
220
-
-
0037454960
-
Host prostaglandin E(2)-EP3 signaling regulates tumor-associated angiogenesis and tumor growth
-
Amano H., Hayashi I., Endo H., et al. Host prostaglandin E(2)-EP3 signaling regulates tumor-associated angiogenesis and tumor growth. J Exp Med 2003, 197:221-232.
-
(2003)
J Exp Med
, vol.197
, pp. 221-232
-
-
Amano, H.1
Hayashi, I.2
Endo, H.3
-
221
-
-
77349125367
-
Host prostaglandin EP3 receptor signaling relevant to tumor-associated lymphangiogenesis
-
Kubo H., Hosono K., Suzuki T., et al. Host prostaglandin EP3 receptor signaling relevant to tumor-associated lymphangiogenesis. Biomed Pharmacother 2010, 64:101-106.
-
(2010)
Biomed Pharmacother
, vol.64
, pp. 101-106
-
-
Kubo, H.1
Hosono, K.2
Suzuki, T.3
-
222
-
-
64549138400
-
Bone marrow-derived EP3-expressing stromal cells enhance tumor-associated angiogenesis and tumor growth
-
Ogawa Y., Suzuki T., Oikawa A., et al. Bone marrow-derived EP3-expressing stromal cells enhance tumor-associated angiogenesis and tumor growth. Biochem Biophys Res Commun 2009, 382:720-725.
-
(2009)
Biochem Biophys Res Commun
, vol.382
, pp. 720-725
-
-
Ogawa, Y.1
Suzuki, T.2
Oikawa, A.3
-
223
-
-
0041816104
-
Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor
-
Buchanan F.G., Wang D., Bargiacchi F., DuBois R.N. Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor. J Biol Chem 2003, 278:35451-35457.
-
(2003)
J Biol Chem
, vol.278
, pp. 35451-35457
-
-
Buchanan, F.G.1
Wang, D.2
Bargiacchi, F.3
DuBois, R.N.4
-
224
-
-
77951157434
-
Prostaglandin E2 promotes lung cancer cell migration via EP4-betaArrestin1-c-Src signalsome
-
Kim J.I., Lakshmikanthan V., Frilot N., Daaka Y. Prostaglandin E2 promotes lung cancer cell migration via EP4-betaArrestin1-c-Src signalsome. Mol Cancer Res 2010, 8:569-577.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 569-577
-
-
Kim, J.I.1
Lakshmikanthan, V.2
Frilot, N.3
Daaka, Y.4
-
225
-
-
0346736504
-
Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion
-
Dohadwala M., Batra R.K., Luo J., et al. Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion. J Biol Chem 2002, 277:50828-50833.
-
(2002)
J Biol Chem
, vol.277
, pp. 50828-50833
-
-
Dohadwala, M.1
Batra, R.K.2
Luo, J.3
-
226
-
-
77956919849
-
PGE2/EP1 signaling pathway enhances ICAM-1 expression and cell motility in oral cancer cells
-
Yang S.-F., Chen M.-K., Hsieh Y.-S., et al. PGE2/EP1 signaling pathway enhances ICAM-1 expression and cell motility in oral cancer cells. J Biol Chem 2010, 285:29808-29816.
-
(2010)
J Biol Chem
, vol.285
, pp. 29808-29816
-
-
Yang, S.-F.1
Chen, M.-K.2
Hsieh, Y.-S.3
-
227
-
-
77649313651
-
Cyclooxygenase-2 enhances alpha2beta1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells
-
Liu J.-F., Fong Y.-C., Chang C.-S., et al. Cyclooxygenase-2 enhances alpha2beta1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells. Mol Cancer 2010, 9:43.
-
(2010)
Mol Cancer
, vol.9
, pp. 43
-
-
Liu, J.-F.1
Fong, Y.-C.2
Chang, C.-S.3
-
228
-
-
0032586845
-
Prostaglandin E2 inhibits T-cell-activation-induced apoptosis and Fas-mediated cellular cytotoxicity by blockade of Fas-ligand induction
-
Porter B.O., Malek T.R. Prostaglandin E2 inhibits T-cell-activation-induced apoptosis and Fas-mediated cellular cytotoxicity by blockade of Fas-ligand induction. Eur J Immunol 1999, 29:2360-2365.
-
(1999)
Eur J Immunol
, vol.29
, pp. 2360-2365
-
-
Porter, B.O.1
Malek, T.R.2
-
229
-
-
4644337725
-
Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in non-small cell lung cancer
-
Krysan K., Dalwadi H., Sharma S., Pold M., Dubinett S. Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in non-small cell lung cancer. Cancer Res 2004, 64:6359-6362.
-
(2004)
Cancer Res
, vol.64
, pp. 6359-6362
-
-
Krysan, K.1
Dalwadi, H.2
Sharma, S.3
Pold, M.4
Dubinett, S.5
-
230
-
-
85047690934
-
Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation
-
Tessner T.G., Muhale F., Riehl T.E., Anant S., Stenson W.F. Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation. J Clin Invest 2004, 114:1676-1685.
-
(2004)
J Clin Invest
, vol.114
, pp. 1676-1685
-
-
Tessner, T.G.1
Muhale, F.2
Riehl, T.E.3
Anant, S.4
Stenson, W.F.5
-
231
-
-
77953478344
-
The proapoptotic BH3-only protein Bim is downregulated in a subset of colorectal cancers and is repressed by antiapoptotic COX-2/PGE2 signalling in colorectal adenoma cells
-
Greenhough A., Wallam C.A., Hicks D.J., Moorghen M., Williams A.C., Paraskeva C. The proapoptotic BH3-only protein Bim is downregulated in a subset of colorectal cancers and is repressed by antiapoptotic COX-2/PGE2 signalling in colorectal adenoma cells. Oncogene 2010, 29:3398-3410.
-
(2010)
Oncogene
, vol.29
, pp. 3398-3410
-
-
Greenhough, A.1
Wallam, C.A.2
Hicks, D.J.3
Moorghen, M.4
Williams, A.C.5
Paraskeva, C.6
-
232
-
-
0021043226
-
Regulation of the immune response by prostaglandins
-
Goodwin J.S., Ceuppens J. Regulation of the immune response by prostaglandins. J Clin Immunol 1983, 3:295-315.
-
(1983)
J Clin Immunol
, vol.3
, pp. 295-315
-
-
Goodwin, J.S.1
Ceuppens, J.2
-
233
-
-
0036498542
-
Cyclooxygenase-2-issued prostaglandin e(2) enhances the production of endogenous IL-10, which down-regulates dendritic cell functions
-
Harizi H., Juzan M., Pitard V., Moreau J.F., Gualde N. Cyclooxygenase-2-issued prostaglandin e(2) enhances the production of endogenous IL-10, which down-regulates dendritic cell functions. J Immunol 2002, 168:2255-2263.
-
(2002)
J Immunol
, vol.168
, pp. 2255-2263
-
-
Harizi, H.1
Juzan, M.2
Pitard, V.3
Moreau, J.F.4
Gualde, N.5
-
234
-
-
0027262191
-
Elevated prostaglandin E2 production by monocytes is responsible for the depressed levels of natural killer and lymphokine-activated killer cell function in patients with breast cancer
-
Baxevanis C.N., Reclos G.J., Gritzapis A.D., Dedousis G.V., Missitzis I., Papamichail M. Elevated prostaglandin E2 production by monocytes is responsible for the depressed levels of natural killer and lymphokine-activated killer cell function in patients with breast cancer. Cancer 1993, 72:491-501.
-
(1993)
Cancer
, vol.72
, pp. 491-501
-
-
Baxevanis, C.N.1
Reclos, G.J.2
Gritzapis, A.D.3
Dedousis, G.V.4
Missitzis, I.5
Papamichail, M.6
-
235
-
-
20444464066
-
Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer
-
Sharma S., Yang S.C., Zhu L., Reckamp K., et al. Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer. Cancer Res 2005, 65:5211-5220.
-
(2005)
Cancer Res
, vol.65
, pp. 5211-5220
-
-
Sharma, S.1
Yang, S.C.2
Zhu, L.3
Reckamp, K.4
-
236
-
-
34249300128
-
Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells
-
Sinha P., Clements V.K., Fulton A.M., Ostrand-Rosenberg S. Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells. Cancer Res 2007, 67:4507-4513.
-
(2007)
Cancer Res
, vol.67
, pp. 4507-4513
-
-
Sinha, P.1
Clements, V.K.2
Fulton, A.M.3
Ostrand-Rosenberg, S.4
-
237
-
-
31544464331
-
Prostaglandin E2 impairs CD4+ T cell activation by inhibition of lck: implications in Hodgkin's lymphoma
-
Chemnitz J.M., Driesen J., Classen S., et al. Prostaglandin E2 impairs CD4+ T cell activation by inhibition of lck: implications in Hodgkin's lymphoma. Cancer Res 2006, 66:1114-1122.
-
(2006)
Cancer Res
, vol.66
, pp. 1114-1122
-
-
Chemnitz, J.M.1
Driesen, J.2
Classen, S.3
-
238
-
-
59849121138
-
Progression of pancreatic adenocarcinoma is significantly impeded with a combination of vaccine and COX-2 inhibition
-
Mukherjee P., Basu G.D., Tinder T.L., et al. Progression of pancreatic adenocarcinoma is significantly impeded with a combination of vaccine and COX-2 inhibition. J Immunol 2009, 182:216-224.
-
(2009)
J Immunol
, vol.182
, pp. 216-224
-
-
Mukherjee, P.1
Basu, G.D.2
Tinder, T.L.3
-
239
-
-
33746906695
-
Cyclooxygenase-2 inhibitor enhances the efficacy of a breast cancer vaccine: role of IDO
-
Basu G.D., Tinder T.L., Bradley J.M., et al. Cyclooxygenase-2 inhibitor enhances the efficacy of a breast cancer vaccine: role of IDO. J Immunol 2006, 177:2391-2402.
-
(2006)
J Immunol
, vol.177
, pp. 2391-2402
-
-
Basu, G.D.1
Tinder, T.L.2
Bradley, J.M.3
-
240
-
-
0030461132
-
Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents
-
Kurumbail R.G., Stevens A.M., Gierse J.K., et al. Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents. Nature 1996, 384:644-648.
-
(1996)
Nature
, vol.384
, pp. 644-648
-
-
Kurumbail, R.G.1
Stevens, A.M.2
Gierse, J.K.3
-
241
-
-
0034655238
-
Chemoprevention of breast cancer in rats by celecoxib, a cyclo-oxygenase 2 inhibitor
-
Harris R.E., Alshafie G.A., Abou-Issa H.M., Seibert K. Chemoprevention of breast cancer in rats by celecoxib, a cyclo-oxygenase 2 inhibitor. Cancer Res 2000, 60:2101-2103.
-
(2000)
Cancer Res
, vol.60
, pp. 2101-2103
-
-
Harris, R.E.1
Alshafie, G.A.2
Abou-Issa, H.M.3
Seibert, K.4
-
242
-
-
0036468287
-
Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo
-
Leahy K.M., Ornberg R.L., Wang Y., Zweifel B.S., Koki A.T., Masferrer J.L. Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo. Cancer Res 2002, 62:625-631.
-
(2002)
Cancer Res
, vol.62
, pp. 625-631
-
-
Leahy, K.M.1
Ornberg, R.L.2
Wang, Y.3
Zweifel, B.S.4
Koki, A.T.5
Masferrer, J.L.6
-
243
-
-
0345549483
-
Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition
-
Totzke G., Schulze-Osthoff K., Janicke R.U. Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition. Oncogene 2003, 22:8021-8030.
-
(2003)
Oncogene
, vol.22
, pp. 8021-8030
-
-
Totzke, G.1
Schulze-Osthoff, K.2
Janicke, R.U.3
-
244
-
-
0036531924
-
Celecoxib exhibits the greatest potency amongst cyclooxygenase (COX) inhibitors for growth inhibition of COX-2-negative hematopoietic and epithelial cell lines
-
Waskewich C., Blumenthal R.D., Li H., Stein R., Goldenberg D.M., Burton J. Celecoxib exhibits the greatest potency amongst cyclooxygenase (COX) inhibitors for growth inhibition of COX-2-negative hematopoietic and epithelial cell lines. Cancer Res 2002, 62:2029-2033.
-
(2002)
Cancer Res
, vol.62
, pp. 2029-2033
-
-
Waskewich, C.1
Blumenthal, R.D.2
Li, H.3
Stein, R.4
Goldenberg, D.M.5
Burton, J.6
-
245
-
-
33745238704
-
Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors
-
Grosch S., Maier T.J., Schiffmann S., Geisslinger G. Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors. J Natl Cancer Inst 2006, 98:736-747.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 736-747
-
-
Grosch, S.1
Maier, T.J.2
Schiffmann, S.3
Geisslinger, G.4
-
246
-
-
0035650943
-
COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib
-
Grosch S., Tegeder I., Niederberger E., Brautigam L., Geisslinger G. COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib. FASEB J 2001, 15:2742-2744.
-
(2001)
FASEB J
, vol.15
, pp. 2742-2744
-
-
Grosch, S.1
Tegeder, I.2
Niederberger, E.3
Brautigam, L.4
Geisslinger, G.5
-
247
-
-
0037106343
-
The cyclo-oxygenase-2 inhibitor celecoxib perturbs intracellular calcium by inhibiting endoplasmic reticulum Ca2+-ATPases: a plausible link with its anti-tumour effect and cardiovascular risks
-
Johnson A.J., Hsu A.L., Lin H.P., Song X., Chen C.S. The cyclo-oxygenase-2 inhibitor celecoxib perturbs intracellular calcium by inhibiting endoplasmic reticulum Ca2+-ATPases: a plausible link with its anti-tumour effect and cardiovascular risks. Biochem J 2002, 366:831-837.
-
(2002)
Biochem J
, vol.366
, pp. 831-837
-
-
Johnson, A.J.1
Hsu, A.L.2
Lin, H.P.3
Song, X.4
Chen, C.S.5
-
248
-
-
1642540579
-
Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition
-
Weber A., Casini A., Heine A., et al. Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition. J Med Chem 2004, 47:550-557.
-
(2004)
J Med Chem
, vol.47
, pp. 550-557
-
-
Weber, A.1
Casini, A.2
Heine, A.3
-
249
-
-
0038030681
-
Do altering in ornithine decarboxylase activity and gene expression contribute to antiproliferative properties of COX inhibitors?
-
Ostrowski J., Wocial T., Skurzak H., Bartnik W. Do altering in ornithine decarboxylase activity and gene expression contribute to antiproliferative properties of COX inhibitors?. Br J Cancer 2003, 88:1143-1151.
-
(2003)
Br J Cancer
, vol.88
, pp. 1143-1151
-
-
Ostrowski, J.1
Wocial, T.2
Skurzak, H.3
Bartnik, W.4
-
250
-
-
25144506566
-
Dimethyl-celecoxib (DMC), a derivative of celecoxib that lacks cyclooxygenase-2-inhibitory function, potently mimics the anti-tumor effects of celecoxib on Burkitt's lymphoma in vitro and in vivo
-
Kardosh A., Wang W., Uddin J., et al. Dimethyl-celecoxib (DMC), a derivative of celecoxib that lacks cyclooxygenase-2-inhibitory function, potently mimics the anti-tumor effects of celecoxib on Burkitt's lymphoma in vitro and in vivo. Cancer Biol Ther 2005, 571-582.
-
(2005)
Cancer Biol Ther
, pp. 571-582
-
-
Kardosh, A.1
Wang, W.2
Uddin, J.3
-
251
-
-
33745226982
-
Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo
-
Pyrko P., Soriano N., Kardosh A., et al. Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo. Mol Cancer 2006, 18-5:19.
-
(2006)
Mol Cancer
, pp. 19
-
-
Pyrko, P.1
Soriano, N.2
Kardosh, A.3
-
252
-
-
45049086884
-
Dimethylcelecoxib inhibits prostaglandin E2 production
-
Wobst I., Schiffmann S., Birod K., et al. Dimethylcelecoxib inhibits prostaglandin E2 production. Biochem Pharmacol 2008, 76:62-69.
-
(2008)
Biochem Pharmacol
, vol.76
, pp. 62-69
-
-
Wobst, I.1
Schiffmann, S.2
Birod, K.3
-
253
-
-
0033776880
-
Cyclooxygenase mechanisms
-
Marnett L.J. Cyclooxygenase mechanisms. Curr Opin Chem Biol 2000, 4:545-552.
-
(2000)
Curr Opin Chem Biol
, vol.4
, pp. 545-552
-
-
Marnett, L.J.1
-
254
-
-
0029056992
-
The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase
-
Loll P.J., Picot D., Garavito R.M. The structural basis of aspirin activity inferred from the crystal structure of inactivated prostaglandin H2 synthase. Nat Struct Biol 1995, 2:637-643.
-
(1995)
Nat Struct Biol
, vol.2
, pp. 637-643
-
-
Loll, P.J.1
Picot, D.2
Garavito, R.M.3
-
255
-
-
0035348486
-
Aspirin-induced activation of the NF-kappaB signaling pathway: a novel mechanism for aspirin-mediated apoptosis in colon cancer cells
-
Stark L.A., Din F.V., Zwacka R.M., Dunlop M.G. Aspirin-induced activation of the NF-kappaB signaling pathway: a novel mechanism for aspirin-mediated apoptosis in colon cancer cells. FASEB J 2001, 15:1273-1275.
-
(2001)
FASEB J
, vol.15
, pp. 1273-1275
-
-
Stark, L.A.1
Din, F.V.2
Zwacka, R.M.3
Dunlop, M.G.4
-
256
-
-
77953283014
-
NSAID sulindac and its analog bind RXRalpha and inhibit RXRalpha-dependent AKT signaling
-
Zhou H., Liu W., Su Y., et al. NSAID sulindac and its analog bind RXRalpha and inhibit RXRalpha-dependent AKT signaling. Cancer Cell 2010, 17:560-573.
-
(2010)
Cancer Cell
, vol.17
, pp. 560-573
-
-
Zhou, H.1
Liu, W.2
Su, Y.3
-
257
-
-
33748196958
-
Celecoxib for the prevention of sporadic colorectal adenomas
-
Bertagnolli M.M., Eagle C.J., Zauber A.G., et al. Celecoxib for the prevention of sporadic colorectal adenomas. N Engl J Med 2006, 355:873-884.
-
(2006)
N Engl J Med
, vol.355
, pp. 873-884
-
-
Bertagnolli, M.M.1
Eagle, C.J.2
Zauber, A.G.3
-
258
-
-
33845288081
-
A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas
-
Baron J.A., Sandler R.S., Bresalier R.S., et al. A randomized trial of rofecoxib for the chemoprevention of colorectal adenomas. Gastroenterology 2006, 131:1674-1682.
-
(2006)
Gastroenterology
, vol.131
, pp. 1674-1682
-
-
Baron, J.A.1
Sandler, R.S.2
Bresalier, R.S.3
-
259
-
-
33748180713
-
Celecoxib for the prevention of colorectal adenomatous polyps
-
Arber N., Eagle C.J., Spicak J., et al. Celecoxib for the prevention of colorectal adenomatous polyps. N Engl J Med 2006, 355:885-895.
-
(2006)
N Engl J Med
, vol.355
, pp. 885-895
-
-
Arber, N.1
Eagle, C.J.2
Spicak, J.3
-
260
-
-
55749105531
-
Cardiovascular events associated with rofecoxib: final analysis of the APPROVe trial
-
Baron J.A., Sandler R.S., Bresalier R.S., et al. Cardiovascular events associated with rofecoxib: final analysis of the APPROVe trial. Lancet 2008, 372:1756-1764.
-
(2008)
Lancet
, vol.372
, pp. 1756-1764
-
-
Baron, J.A.1
Sandler, R.S.2
Bresalier, R.S.3
-
261
-
-
64049109107
-
Cyclooxygenase-2 (Cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung
-
Harris R.E. Cyclooxygenase-2 (Cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung. Inflammopharmacol 2009, 17:55-67.
-
(2009)
Inflammopharmacol
, vol.17
, pp. 55-67
-
-
Harris, R.E.1
-
262
-
-
31044441042
-
Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities
-
Grosser T., Fries S., FitzGerald G.A. Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities. J Clin Invest 2006, 116:4-15.
-
(2006)
J Clin Invest
, vol.116
, pp. 4-15
-
-
Grosser, T.1
Fries, S.2
FitzGerald, G.A.3
-
263
-
-
67549122884
-
Levels of prostaglandin E metabolite and leukotriene E4 are increased in the urine of smokers: evidence that celecoxib shunts arachidonic acid into the 5-Lipoxygenase pathway
-
Duffield-Lillico A.J., Boyle J.O., Zhou X.K., et al. Levels of prostaglandin E metabolite and leukotriene E4 are increased in the urine of smokers: evidence that celecoxib shunts arachidonic acid into the 5-Lipoxygenase pathway. Cancer Prev Res 2009, 2:322-329.
-
(2009)
Cancer Prev Res
, vol.2
, pp. 322-329
-
-
Duffield-Lillico, A.J.1
Boyle, J.O.2
Zhou, X.K.3
-
264
-
-
77954613539
-
Effective reduction of gastric cancer risk with regular use of nonsteroidal anti-inflammatory drugs in Helicobacter pylori-infected patients
-
Wu C.Y., Wu M.S., Kuo K.N., Wang C.B., Chen Y.J., Lin J.T. Effective reduction of gastric cancer risk with regular use of nonsteroidal anti-inflammatory drugs in Helicobacter pylori-infected patients. J Clin Oncol 2010, 28:2952-2957.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2952-2957
-
-
Wu, C.Y.1
Wu, M.S.2
Kuo, K.N.3
Wang, C.B.4
Chen, Y.J.5
Lin, J.T.6
-
265
-
-
49549122075
-
Cyclooxygenase inhibitors down regulate P-glycoprotein in human colorectal Caco-2 cell line
-
Zrieki A., Farinotti R., Buyse M. Cyclooxygenase inhibitors down regulate P-glycoprotein in human colorectal Caco-2 cell line. Pharm Res 2008, 25:1991-2001.
-
(2008)
Pharm Res
, vol.25
, pp. 1991-2001
-
-
Zrieki, A.1
Farinotti, R.2
Buyse, M.3
-
266
-
-
23244437041
-
Cyclooxygenase 2 inhibition promotes IFN-gamma-dependent enhancement of antitumor responses
-
Sharma S., Zhu L., Yang S.C., et al. Cyclooxygenase 2 inhibition promotes IFN-gamma-dependent enhancement of antitumor responses. J Immunol 2005, 17:813-819.
-
(2005)
J Immunol
, vol.17
, pp. 813-819
-
-
Sharma, S.1
Zhu, L.2
Yang, S.C.3
-
267
-
-
11244315274
-
Continuous low-dose chemotherapy plus inhibition of cyclooxygenase-2 as an antiangiogenic therapy of glioblastoma multiforme
-
Tuettenberg J., Grobholz R., Korn T., Wenz F., Erber R., Vajkoczy P. Continuous low-dose chemotherapy plus inhibition of cyclooxygenase-2 as an antiangiogenic therapy of glioblastoma multiforme. J Cancer Res Clin Oncol 2005, 131:31-40.
-
(2005)
J Cancer Res Clin Oncol
, vol.131
, pp. 31-40
-
-
Tuettenberg, J.1
Grobholz, R.2
Korn, T.3
Wenz, F.4
Erber, R.5
Vajkoczy, P.6
-
268
-
-
3042524200
-
Pilot study of celecoxib and infusional 5-fluorouracil as second-line treatment for advanced pancreatic carcinoma
-
Milella M., Gelibter A., Di Cosimo S., et al. Pilot study of celecoxib and infusional 5-fluorouracil as second-line treatment for advanced pancreatic carcinoma. Cancer 2004, 101:133-138.
-
(2004)
Cancer
, vol.101
, pp. 133-138
-
-
Milella, M.1
Gelibter, A.2
Di Cosimo, S.3
-
269
-
-
77649140377
-
Cyclooxygenase-2 inhibition does not improve the reduction in ductal carcinoma in situ proliferation with aromatase inhibitor therapy: results of the ERISAC randomized placebo-controlled trial
-
Bundred N.J., Cramer A., Morris J., et al. Cyclooxygenase-2 inhibition does not improve the reduction in ductal carcinoma in situ proliferation with aromatase inhibitor therapy: results of the ERISAC randomized placebo-controlled trial. Clin Cancer Res 2010, 16:1605-1612.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1605-1612
-
-
Bundred, N.J.1
Cramer, A.2
Morris, J.3
-
270
-
-
77649154782
-
Phase II, randomized, placebo-controlled trial of neoadjuvant celecoxib in men with clinically localized prostate cancer: evaluation of drug-specific biomarkers
-
Antonarakis E.S., Heath E.I., Walczak J.R., et al. Phase II, randomized, placebo-controlled trial of neoadjuvant celecoxib in men with clinically localized prostate cancer: evaluation of drug-specific biomarkers. J Clin Oncol 2009, 4986-4993.
-
(2009)
J Clin Oncol
, pp. 4986-4993
-
-
Antonarakis, E.S.1
Heath, E.I.2
Walczak, J.R.3
-
271
-
-
39749149266
-
Eicosanoid modulation in advanced lung cancer: cyclooxygenase-2 expression is a positive predictive factor for celecoxib + chemotherapy-Cancer and Leukemia Group B Trial 30203
-
Edelman M.J., Watson D., Wang X., et al. Eicosanoid modulation in advanced lung cancer: cyclooxygenase-2 expression is a positive predictive factor for celecoxib + chemotherapy-Cancer and Leukemia Group B Trial 30203. J Clin Oncol 2008, 848-855.
-
(2008)
J Clin Oncol
, pp. 848-855
-
-
Edelman, M.J.1
Watson, D.2
Wang, X.3
-
272
-
-
67249157211
-
15-hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors
-
Yan M., Myung S.-J., Fink S.P., et al. 15-hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors. Proc Natl Acad Sci USA 2009, 106:9409-9413.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 9409-9413
-
-
Yan, M.1
Myung, S.-J.2
Fink, S.P.3
-
273
-
-
79951726704
-
-
http://wwwclinicaltrials.gov.
-
-
-
-
274
-
-
77951738107
-
Selective visualization of cyclooxygenase-2 in inflammation and cancer by targeted fluorescent imaging agents
-
Uddin M.J., Crews B.C., Blobaum A.L., et al. Selective visualization of cyclooxygenase-2 in inflammation and cancer by targeted fluorescent imaging agents. Cancer Res 2010, 70:3618-3627.
-
(2010)
Cancer Res
, vol.70
, pp. 3618-3627
-
-
Uddin, M.J.1
Crews, B.C.2
Blobaum, A.L.3
|