Role of p300 and PCAF in regulating cyclooxygenase-2 promoter activation by inflammatory mediators

Blood

Volumn 103, Issue 6, 2004, Pages 2135-2142

  Deng, Wu Guo ^a   Zhu, Ying ^a   Wu, Kenneth K ^a,b  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTACOID; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYCLOOXYGENASE 2; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE PCAF; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN P300; ROSCOVITINE;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; DELETION MUTANT; FIBROBLAST; GENE OVEREXPRESSION; INFLAMMATION; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION;

EID: 1542343955     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-09-3131     Document Type: Article

References (35)

1. Smith WL, Garavito RM, DeWitt DL. Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2. J Biol Chem. 1996;271:33157-33160.
2. Wu KK. Inducible cyclooxygenase and nitric oxide synthase. Adv Pharmacol. 1995;33:179-207.
3. Vane JR, Mitchell JA, Appleton I, at al. Inducible isoforms of COX and NOS in inflammation. Proc Natl Acad Sci U S A. 1994;91:2046-2050.
4. Seibert K, Zhang Y, Leahy K, et al. Pharmacological and biochemical demonstration of the role of COX-2 in inflammation and pain. Proc Natl Acad Sci U S A. 1994;91:12013-12017.
5. Cipollone F, Prontera C, Pini B, et al. Overexpression of functionally coupled cyclooxygenase-2 and prostaglandin E synthase in symptomatic atherosclerotic plaques as a basis of prostaglandin E(2)-dependent plaque instability. Circulation. 2001;104:921-927.
6. Tsujii M, DuBois RN. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell. 1995;83:493-501.
7. Levy GN. Prostaglandin H synthases, nonsteroidal anti-inflammatory drugs, and colon cancer. FASEB J. 1997;11:234-247.
8. Oshima M, Dinchuk JE, Kargman SL, et al. Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell. 1996;67:803-809.
9. Kosaka T, Miyata A, Ihara H, et al. Characterization of human gene (PTGS2) encoding COX-2. Eur J Biochem. 1994;221:889-897.
10. Tazawa R, Xu XM, Wu KK, Wang LH. Characterization of the genomic structure, chromosomal location and promoter of human prostaglandin H synthase-2 gene. Biochem Biophys Res Commun. 1994;203:190-199.
11. Schroer K, Zhu Y, Saunders MA, et al. The obligatory role of cyclic AMP response element in cyclooxygenase-2 promoter induction and feedback regulation by inflammatory mediators. Circulation. 2002;105:2760-2765.
12. Inoue H, Yokoyama O, Hara S, Tone Y, Tanaka T. Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. J Biol Chem. 1995;270:24965-24971.
13. Mestre JR, Mackrell PJ, Rivadeneira DE, Stapleton PP, Tanabe T, Daly JM. Redundancy in the signaling pathway and promoter events regulating COX-2 gene expression in endotoxin-treated macrophages. J Biol Chem. 2001;276:3977-3982.
14. Saunders MA, Sansores-Garcia L, Gilroy DW, Wu KK. Selective suppression of CCAAT/enhancer-binding protein β binding and cyclooxygenase-2 promoter activity by sodium salicylate in quiescent human fibroblasts. J Biol Chem. 2001;276:18897-18904.
15. Deng W-G, Zhu Y, Wu KK. Up-regulation of p300 binding and p50 acetylation in tumor necrosis factor-alpha-induced cyclooxygenase-2 promoter activation. J Biol Chem. 2003;278:4770-4777.
16. Subbaramaiah K, Cole PA, Dannenberg AJ. Retinoids and camosol suppress COX-2 transcription by CREB-binding protein/p300-dependent and independent mechanism. Cancer Res. 2002;62: 2522-2530.
17. Janknecht R, Hunter T. Transcription: a growing coactivator network. Nature (Lond). 1996;383:22-23.
18. Shikama N, Lyon J, La Thange NB. The p300/CBP family: integrating signals with transcription factors and chromatin. Trends Cell Biol. 1997;7: 230-236.
19. Goodman RH, Smolik S. CBP/p300 in cell growth, transformation, and development. Genes Dev. 2000;14:1553-1577.
20. Bordoli L, Husser S, Luthi U, Netsch M, Osmani H, Eckner R. Functional analysis of the p300 acetyltransferase domain: the PHD finger of p300 but not of CBP is dispensable for enzymatic activity. Nucleic Acids Res. 2001;29:4462-4471.
21. Gilroy DW, Saunders MA, Sansores-Garcia L, Matijevic-Aleksic N, Wu KK. Cell cycle-dependent expression of cyclooxygenase-2 in human fibroblasts. FASEB J. 2001;152:288-90.
22. Cieslik K, Zhu Y, Wu KK. Salicylate suppresses macrophage nitric-oxide synthase-2 and cyclooxygenase-2 expression by inhibiting CCAAT/enhancer-binding protein-beta binding via a common signaling pathway. J Biol Chem. 2002;277: 49304-49310.
23. Xu XM, Sansores-Garcia L, Chen XM, Du M, Matijevic-Aleksic N, Wu KK. Suppression of inducible cyclooxygenase-2 gene transcription by aspirin and sodium salicylate. Proc Natl Acad Sci U S A. 1999;96:5292-5297.
24. Zhu Y, Saunders M, Yeh H, Deng W-G, Wu KK. Dynamic regulation of cyclooxygenase-2 promoter activity by isoforms of CCAAT/enhancer-binding proteins. J Biol Chem. 2002;277:6923-6928.
25. Wallberg AE, Pedersen K, Lendahl U, Roeder RG. p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by notch intracellular domains in vitro. Mol Cell Biol. 2002;22:7812-7819.
26. Eckner R, Ewen ME, Newsome D, et al. Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev. 1994;8:869-884.
27. Ogryzko VV, Schiltz RL, Russanova V, Howard BH, Nakatani Y. The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell. 1996;87:953-959.
28. Ait-Si-Ali S, Ramirez S, Barre FX, et al. Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A. Nature. 1998;396:184-186.
29. Yao YL, Yang WM, Seto E. Regulation of transcription factor YY1 by acetylation and deacetylation. Mol Cell Biol. 2001;21:5979-5991.
30. Horvai AE, Xu L, Korzus E, et al. Nuclear Integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300. Proc Natl Acad Sci U S A. 1997;94: 1074-1079.
31. Chen Lf, Fischle W, Verdin E, Greene WC. Duration of nuclear NF-kappaB action regulated by reversible acetylation. Science. 2001;293:1653-1657.
32. Gu W, Roeder RG. Activation of p53 sequence specific DNA binding by acetylation of the p53 C-terminal domain. Cell. 1997;90:595-606.
33. Perkins ND, Felzien LK, Betts JC, Leung K, Beach DH, Nabel GJ. Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator. Science. 1997;275:523-527.
34. Gilroy DW, Saunders MA, Wu KK. COX-2 expression and cell cycle progression in human fibroblasts. Am J Physiol Cell Physiol. 2001;281: C188-C194.
35. Ashbumer BP, Westerheide SD, Baldwin AS Jr. The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression. Mol Cell Biol. 2001;21:7065-7077.