메뉴 건너뛰기




Volumn 66, Issue 24, 2006, Pages 11700-11708

RhoA mediates cyclooxygenase-2 signaling to disrupt the formation of adherens junctions and increase cell motility

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CATENIN; CYCLOOXYGENASE 2; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; UVOMORULIN;

EID: 33846264945     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-1818     Document Type: Article
Times cited : (47)

References (44)
  • 1
    • 18444408375 scopus 로고    scopus 로고
    • COX-2: A molecular target for colorectal cancer prevention
    • Brown JR, DuBois RN. COX-2: A molecular target for colorectal cancer prevention. J Clin Oncol 2005;23:2840-55.
    • (2005) J Clin Oncol , vol.23 , pp. 2840-2855
    • Brown, J.R.1    DuBois, R.N.2
  • 2
    • 29244449354 scopus 로고    scopus 로고
    • Prostaglandins and cancer
    • Wang D, DuBois RN. Prostaglandins and cancer. Gut 2006;55:115-22.
    • (2006) Gut , vol.55 , pp. 115-122
    • Wang, D.1    DuBois, R.N.2
  • 3
    • 1042267263 scopus 로고    scopus 로고
    • Cell adhesion and signaling by cadherins and Ig-CAMs in cancer
    • Cavallaro U, Christofori G. Cell adhesion and signaling by cadherins and Ig-CAMs in cancer. Nat Rev Cancer 2004;4:118-32.
    • (2004) Nat Rev Cancer , vol.4 , pp. 118-132
    • Cavallaro, U.1    Christofori, G.2
  • 4
    • 0842281652 scopus 로고    scopus 로고
    • Rho and Rac take center stage
    • Burridge K, Wennerberg K. Rho and Rac take center stage. Cell 2004;116:167-79.
    • (2004) Cell , vol.116 , pp. 167-179
    • Burridge, K.1    Wennerberg, K.2
  • 5
    • 0141756144 scopus 로고    scopus 로고
    • Role of Rho-family proteins in cell adhesion and cancer
    • Malliri A, Collard JG. Role of Rho-family proteins in cell adhesion and cancer. Curr Opin Cell Biol 2003;15:583-9.
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 583-589
    • Malliri, A.1    Collard, J.G.2
  • 6
    • 4143131016 scopus 로고    scopus 로고
    • The cross-Rho'ds of cell-cell adhesion
    • Jaffer ZM, Chernoff J. The cross-Rho'ds of cell-cell adhesion. J Biol Chem 2004;279:35123-6.
    • (2004) J Biol Chem , vol.279 , pp. 35123-35126
    • Jaffer, Z.M.1    Chernoff, J.2
  • 8
    • 0038679226 scopus 로고    scopus 로고
    • Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma
    • Horiuchi A, Imai T, Wang C, et al. Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma. Lab Invest 2003;83:861-70.
    • (2003) Lab Invest , vol.83 , pp. 861-870
    • Horiuchi, A.1    Imai, T.2    Wang, C.3
  • 9
    • 1242317791 scopus 로고    scopus 로고
    • Expression of seven main Rho family members in gastric carcinoma
    • Pan Y, Bi F, Liu N, et al. Expression of seven main Rho family members in gastric carcinoma, Biochem Biophys Res Commun 2004;315:686-91.
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 686-691
    • Pan, Y.1    Bi, F.2    Liu, N.3
  • 10
    • 0642348940 scopus 로고    scopus 로고
    • The small GTPase RhoA has greater expression in small cell lung carcinoma than in non-small cell lung carcinoma and contributes to their unique morphologies
    • Varker KA, Phelps SH, King MM, Williams CL. The small GTPase RhoA has greater expression in small cell lung carcinoma than in non-small cell lung carcinoma and contributes to their unique morphologies. Int J Oncol 2003;22:671-81.
    • (2003) Int J Oncol , vol.22 , pp. 671-681
    • Varker, K.A.1    Phelps, S.H.2    King, M.M.3    Williams, C.L.4
  • 11
    • 0036305635 scopus 로고    scopus 로고
    • ROCK and Dia have opposing effects on adherens junctions downstream of Rho
    • Sahai E, Marshall CJ. ROCK and Dia have opposing effects on adherens junctions downstream of Rho. Nat Cell Biol 2002;4:408-15.
    • (2002) Nat Cell Biol , vol.4 , pp. 408-415
    • Sahai, E.1    Marshall, C.J.2
  • 12
    • 10844230332 scopus 로고    scopus 로고
    • Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis
    • Croft DR, Sahai E, Mavria G, et al. Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis. Cancer Res 2004;64:8994-9001.
    • (2004) Cancer Res , vol.64 , pp. 8994-9001
    • Croft, D.R.1    Sahai, E.2    Mavria, G.3
  • 13
    • 0028803728 scopus 로고
    • Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
    • Tsujii M, DuBois RN. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 1995;83:493-501.
    • (1995) Cell , vol.83 , pp. 493-501
    • Tsujii, M.1    DuBois, R.N.2
  • 14
    • 33744925683 scopus 로고    scopus 로고
    • Cyclooxygenase-2-dependent regulation of E-cadherin: Prostaglandin E2 induces transcriptional repressors ZEB1 and Snail in non-small cell lung cancer
    • Dohadwala M, Yang S-C, Luo J, et al. Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E2 induces transcriptional repressors ZEB1 and Snail in non-small cell lung cancer. Cancer Res 2006;66:5338-45.
    • (2006) Cancer Res , vol.66 , pp. 5338-5345
    • Dohadwala, M.1    Yang, S.-C.2    Luo, J.3
  • 16
    • 0033756160 scopus 로고    scopus 로고
    • Cyclooxygenase 2 promotes cell survival by stimulation of dynein light chain expression and inhibition of neuronal nitric oxide synthase activity
    • Chang YW, Jakobi R, McGinty A, Foschi M, Dunn MJ, Sorokin A. Cyclooxygenase 2 promotes cell survival by stimulation of dynein light chain expression and inhibition of neuronal nitric oxide synthase activity. Mol Cell Biol 2000;20:8571-9.
    • (2000) Mol Cell Biol , vol.20 , pp. 8571-8579
    • Chang, Y.W.1    Jakobi, R.2    McGinty, A.3    Foschi, M.4    Dunn, M.J.5    Sorokin, A.6
  • 17
    • 32144454684 scopus 로고    scopus 로고
    • Purification of TAT-C3 exoenzyme
    • Sahai E, Olson MF. Purification of TAT-C3 exoenzyme. Methods Enzymol 2006;406:128-40.
    • (2006) Methods Enzymol , vol.406 , pp. 128-140
    • Sahai, E.1    Olson, M.F.2
  • 18
    • 0029915841 scopus 로고    scopus 로고
    • Molecular cloning and sequencing of the cytostatic G protein-activated protein kinase PAK I
    • Jakobi R, Chen CJ, Tuazon PT, Traugh JA. Molecular cloning and sequencing of the cytostatic G protein-activated protein kinase PAK I. J Biol Chem 1996;271:6206-11.
    • (1996) J Biol Chem , vol.271 , pp. 6206-6211
    • Jakobi, R.1    Chen, C.J.2    Tuazon, P.T.3    Traugh, J.A.4
  • 19
    • 0033777071 scopus 로고    scopus 로고
    • Determination of GTP loading on Rho
    • Ren XD, Schwartz MA. Determination of GTP loading on Rho. Methods Enzymol 2000;325:264-72.
    • (2000) Methods Enzymol , vol.325 , pp. 264-272
    • Ren, X.D.1    Schwartz, M.A.2
  • 20
    • 0034985396 scopus 로고    scopus 로고
    • Nonradioactive determination of Ras-GTP levels using activated ras interaction assay
    • Taylor SJ, Resnick RJ, Shalloway D. Nonradioactive determination of Ras-GTP levels using activated ras interaction assay. Methods Enzymol 2001;333:333-42.
    • (2001) Methods Enzymol , vol.333 , pp. 333-342
    • Taylor, S.J.1    Resnick, R.J.2    Shalloway, D.3
  • 21
    • 0034799994 scopus 로고    scopus 로고
    • Assay of Cdc42, Rac, and Rho GTPase activation by affinity methods
    • Benard V, Bokoch GM. Assay of Cdc42, Rac, and Rho GTPase activation by affinity methods. Methods Enzymol 2002;345:349-59.
    • (2002) Methods Enzymol , vol.345 , pp. 349-359
    • Benard, V.1    Bokoch, G.M.2
  • 22
    • 26444564805 scopus 로고    scopus 로고
    • Differential regulation of cyclooxygenase 2 expression by small GTPases Ras, Rac1, and RhoA
    • Chang YW, Putzer K, Ren L, et al. Differential regulation of cyclooxygenase 2 expression by small GTPases Ras, Rac1, and RhoA. J Cell Biochem 2005;96:314-29.
    • (2005) J Cell Biochem , vol.96 , pp. 314-329
    • Chang, Y.W.1    Putzer, K.2    Ren, L.3
  • 23
    • 0021971693 scopus 로고
    • Dome formation by a human colonic adenocarcinoma cell line (HCA-7)
    • Kirkland SC. Dome formation by a human colonic adenocarcinoma cell line (HCA-7). Cancer Res 1985;45:3790-5.
    • (1985) Cancer Res , vol.45 , pp. 3790-3795
    • Kirkland, S.C.1
  • 24
    • 0038297351 scopus 로고    scopus 로고
    • Colon cancer cells with high invasive potential are susceptible to induction of apoptosis by a selective COX-2 inhibitor
    • Chen WS, Liu JH, Wei SJ, Liu JM, Hong CY, Yang WK. Colon cancer cells with high invasive potential are susceptible to induction of apoptosis by a selective COX-2 inhibitor. Cancer Sci 2003;94:253-8.
    • (2003) Cancer Sci , vol.94 , pp. 253-258
    • Chen, W.S.1    Liu, J.H.2    Wei, S.J.3    Liu, J.M.4    Hong, C.Y.5    Yang, W.K.6
  • 25
    • 0042916422 scopus 로고    scopus 로고
    • Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors
    • Pai R, Nakamura T, Moon WS, Tarnawski AS. Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors. FASEB J 2003;17:1640-7.
    • (2003) FASEB J , vol.17 , pp. 1640-1647
    • Pai, R.1    Nakamura, T.2    Moon, W.S.3    Tarnawski, A.S.4
  • 26
    • 0035266256 scopus 로고    scopus 로고
    • Aberrant activation of c-kit protects colon carcinoma cells against apoptosis and enhances their invasive potential
    • Bellone G, Carbone A, Sibona N, et al. Aberrant activation of c-kit protects colon carcinoma cells against apoptosis and enhances their invasive potential. Cancer Res 2001;61:2200-6.
    • (2001) Cancer Res , vol.61 , pp. 2200-2206
    • Bellone, G.1    Carbone, A.2    Sibona, N.3
  • 27
    • 0032939619 scopus 로고    scopus 로고
    • Rho GTPases are overexpressed in human tumors
    • Fritz G, Just I, Kaina B. Rho GTPases are overexpressed in human tumors. Int J Cancer 1999;81:682-7.
    • (1999) Int J Cancer , vol.81 , pp. 682-687
    • Fritz, G.1    Just, I.2    Kaina, B.3
  • 28
    • 0347379871 scopus 로고    scopus 로고
    • Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors and exhibits selective downstream signaling
    • Matos P, Collard JG, Jordan P. Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors and exhibits selective downstream signaling. J Biol Chem 2003;278:50442-8.
    • (2003) J Biol Chem , vol.278 , pp. 50442-50448
    • Matos, P.1    Collard, J.G.2    Jordan, P.3
  • 29
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: A review
    • Bos JL. Ras oncogenes in human cancer: a review. Cancer Res 1989;49:4682-9.
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 30
    • 0345306729 scopus 로고    scopus 로고
    • Oncogenic Ki-ras inhibits the expression of interferon-responsive genes through inhibition of STAT1 and STAT2 expression
    • Klampfer L, Huang J, Corner G, et al. Oncogenic Ki-ras inhibits the expression of interferon-responsive genes through inhibition of STAT1 and STAT2 expression. J Biol Chem 2003;278:46278-87.
    • (2003) J Biol Chem , vol.278 , pp. 46278-46287
    • Klampfer, L.1    Huang, J.2    Corner, G.3
  • 31
    • 0035899332 scopus 로고    scopus 로고
    • Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines
    • Gayet J, Zhou XP, Duval A, et al. Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines. Oncogene 2001;20:5025-32.
    • (2001) Oncogene , vol.20 , pp. 5025-5032
    • Gayet, J.1    Zhou, X.P.2    Duval, A.3
  • 32
    • 33746658154 scopus 로고    scopus 로고
    • Ohta Y, Hartwig JH, Stossel TP. FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling. Nat Cell Biol 2006;8:803-14.
    • Ohta Y, Hartwig JH, Stossel TP. FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling. Nat Cell Biol 2006;8:803-14.
  • 33
    • 0028139275 scopus 로고
    • Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase
    • Copeland RA, Williams JM, Giannaras J, et al. Mechanism of selective inhibition of the inducible isoform of prostaglandin G/H synthase. Proc Natl Acad Sci U S A 1994;91:11202-6.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 11202-11206
    • Copeland, R.A.1    Williams, J.M.2    Giannaras, J.3
  • 34
    • 0029899186 scopus 로고    scopus 로고
    • A single amino acid difference between cyclooxygenase-1 (COX-1) and -2(COX-2) reverses the selectivity of COX-2 specific inhibitors
    • Gierse JK, McDonald JJ, Hauser SD, Rangwala SH, Koboldt CM, Seibert K. A single amino acid difference between cyclooxygenase-1 (COX-1) and -2(COX-2) reverses the selectivity of COX-2 specific inhibitors. J Biol Chem 1996;271:15810-4.
    • (1996) J Biol Chem , vol.271 , pp. 15810-15814
    • Gierse, J.K.1    McDonald, J.J.2    Hauser, S.D.3    Rangwala, S.H.4    Koboldt, C.M.5    Seibert, K.6
  • 35
    • 13444266910 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: Identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-lyl)benze nesulfonamide (SC-58635, celecoxib)
    • Penning TD, Talley JJ, Bertenshaw SR, et al. Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-lyl)benze nesulfonamide (SC-58635, celecoxib). J Med Chem 1997;40:1347-65.
    • (1997) J Med Chem , vol.40 , pp. 1347-1365
    • Penning, T.D.1    Talley, J.J.2    Bertenshaw, S.R.3
  • 37
    • 0034721853 scopus 로고    scopus 로고
    • Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells
    • Shao J, Sheng H, Inoue H, Morrow JD, DuBois RN. Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells. J Biol Chem 2000;275:33951-6.
    • (2000) J Biol Chem , vol.275 , pp. 33951-33956
    • Shao, J.1    Sheng, H.2    Inoue, H.3    Morrow, J.D.4    DuBois, R.N.5
  • 38
    • 0029011449 scopus 로고
    • The enterotoxin from Clostridium difficile (ToxA) monoglucosylates the Rho proteins
    • Just I, Wilm M, Selzer J, et al. The enterotoxin from Clostridium difficile (ToxA) monoglucosylates the Rho proteins. J Biol Chem 1995;270:13932-6.
    • (1995) J Biol Chem , vol.270 , pp. 13932-13936
    • Just, I.1    Wilm, M.2    Selzer, J.3
  • 39
    • 0029860810 scopus 로고    scopus 로고
    • Prostaglandin E receptor EP3 subtype induces neurite retraction via small GTPase Rho
    • Katoh H, Negishi M, Ichikawa A. Prostaglandin E receptor EP3 subtype induces neurite retraction via small GTPase Rho. J Biol Chem 1996;271:29780-4.
    • (1996) J Biol Chem , vol.271 , pp. 29780-29784
    • Katoh, H.1    Negishi, M.2    Ichikawa, A.3
  • 40
    • 0141763515 scopus 로고    scopus 로고
    • Involvement of Rho-kinase in contraction of guinea-pig aorta induced by prostanoid EP3 receptor agonists
    • Shum WW, Le GY, Jones RL, Gurney AM, Sasaki Y. Involvement of Rho-kinase in contraction of guinea-pig aorta induced by prostanoid EP3 receptor agonists. Br J Pharmacol 2003;139:1449-61.
    • (2003) Br J Pharmacol , vol.139 , pp. 1449-1461
    • Shum, W.W.1    Le, G.Y.2    Jones, R.L.3    Gurney, A.M.4    Sasaki, Y.5
  • 41
    • 0037195421 scopus 로고    scopus 로고
    • 3-dependent endothelial cell adhesion, Rac-activation, and spreading through cAMP/PKA-dependent signaling
    • 3-dependent endothelial cell adhesion, Rac-activation, and spreading through cAMP/PKA-dependent signaling. J Biol Chem 2002;277:45838-46.
    • (2002) J Biol Chem , vol.277 , pp. 45838-45846
    • Dormond, O.1    Bezzi, M.2    Mariotti, A.3    Ruegg, C.4
  • 42
    • 0033615966 scopus 로고    scopus 로고
    • Rac downregulates Rho activity: Reciprocal balance between both GTPases determines cellular morphology and migratory behavior
    • Sander EE, ten Klooster JP, van Delft S, van der Kammen RA, Collard JG. Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J Cell Biol 1999;147:1009-22.
    • (1999) J Cell Biol , vol.147 , pp. 1009-1022
    • Sander, E.E.1    ten Klooster, J.P.2    van Delft, S.3    van der Kammen, R.A.4    Collard, J.G.5
  • 43
    • 4143146567 scopus 로고    scopus 로고
    • Oncogenic K-ras drives cell cycle progression and phenotypic conversion of primary pancreatic duct epithelial cells
    • Agbunag C, Bar-Sagi D. Oncogenic K-ras drives cell cycle progression and phenotypic conversion of primary pancreatic duct epithelial cells. Cancer Res 2004;64:5659-63.
    • (2004) Cancer Res , vol.64 , pp. 5659-5663
    • Agbunag, C.1    Bar-Sagi, D.2
  • 44
    • 4544320012 scopus 로고    scopus 로고
    • Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor δ
    • Wang D, Wang H, Shi Q, Katkuri S, et al. Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor δ. Cancer Cell 2004;6:285-95.
    • (2004) Cancer Cell , vol.6 , pp. 285-295
    • Wang, D.1    Wang, H.2    Shi, Q.3    Katkuri, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.