-
1
-
-
33847737716
-
DNA damage checkpoints: From initiation to recovery or adaptation
-
DOI 10.1016/j.ceb.2007.02.009, PII S0955067407000233
-
Bartek J, Lukas J. DNA damage checkpoints: From initiation to recovery or adaptation. Curr Opin Cell Biol 2007; 19:238-45. (Pubitemid 46386406)
-
(2007)
Current Opinion in Cell Biology
, vol.19
, Issue.2
, pp. 238-245
-
-
Bartek, J.1
Lukas, J.2
-
2
-
-
0035449355
-
Cell cycle checkpoint signaling through the ATM and ATR kinases
-
DOI 10.1101/gad.914401
-
Abraham RT. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev 2001; 15:2177-96. (Pubitemid 32843830)
-
(2001)
Genes and Development
, vol.15
, Issue.17
, pp. 2177-2196
-
-
Abraham, R.T.1
-
3
-
-
33745823159
-
The ATM-mediated DNA-damage response: Taking shape
-
DOI 10.1016/j.tibs.2006.05.004, PII S0968000406001381
-
Shiloh Y. The ATM-mediated DNA-damage response: Yaking shape. Trends Biochem Sci 2006; 31:402-10. (Pubitemid 44038916)
-
(2006)
Trends in Biochemical Sciences
, vol.31
, Issue.7
, pp. 402-410
-
-
Shiloh, Y.1
-
4
-
-
9244251125
-
Cell-cycle checkpoints and cancer
-
DOI 10.1038/nature03097
-
Kastan MB, Bartek J. Cell-cycle checkpoints and cancer. Nature 2004; 432:316-23. (Pubitemid 39551659)
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 316-323
-
-
Kastan, M.B.1
Bartek, J.2
-
5
-
-
36749022214
-
The DNA Damage Response: Ten Years after
-
DOI 10.1016/j.molcel.2007.11.015, PII S1097276507007836
-
Harper JW, Elledge SJ. The DNA damage response: ten years after. Mol Cell 2007; 28:739-45. (Pubitemid 350217064)
-
(2007)
Molecular Cell
, vol.28
, Issue.5
, pp. 739-745
-
-
Harper, J.W.1
Elledge, S.J.2
-
6
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
DOI 10.1038/nature03482
-
Bartkova J, Horejsi Z, Koed K, Kramer A, Tort F, Zieger K, et al. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 2005; 434:864-70. (Pubitemid 40558993)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 864-870
-
-
Bartkova, J.1
Horejsi, Z.2
Koed, K.3
Kramer, A.4
Tort, F.5
Zleger, K.6
Guldberg, P.7
Sehested, M.8
Nesland, J.M.9
Lukas, C.10
Orntoft, T.11
Lukas, J.12
Bartek, J.13
-
7
-
-
17244366865
-
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
-
DOI 10.1038/nature03485
-
Gorgoulis VG, Vassiliou LV, Karakaidos P, Zacharatos P, Kotsinas A, Liloglou T, et al. Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 2005; 434:907-13. (Pubitemid 40559004)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 907-913
-
-
Gorgoulis, V.G.1
Vassiliou, L.-V.F.2
Karakaidos, P.3
Zacharatos, P.4
Kotsinas, A.5
Liloglou, T.6
Venere, M.7
DiTullio Jr., R.A.8
Kastrinakis, N.G.9
Levy, B.10
Kletsas, D.11
Yoneta, A.12
Herlyn, M.13
Kittas, C.14
Halazonetis, T.D.15
-
8
-
-
0037178723
-
ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones
-
DOI 10.1126/science.1071398
-
Cha RS, Kleckner N. ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones. Science 2002; 297:602-6. (Pubitemid 34815344)
-
(2002)
Science
, vol.297
, Issue.5581
, pp. 602-606
-
-
Cha, R.S.1
Kleckner, N.2
-
9
-
-
0037074013
-
ATR regulates fragile site stability
-
DOI 10.1016/S0092-8674(02)01113-3
-
Casper AM, Nghiem P, Arlt MF, Glover TW. ATR regulates fragile site stability. Cell 2002; 111:779-89. (Pubitemid 36106400)
-
(2002)
Cell
, vol.111
, Issue.6
, pp. 779-789
-
-
Casper, A.M.1
Nghiem, P.2
Arlt, M.F.3
Glover, T.W.4
-
10
-
-
0036849432
-
Checking on the fork: The DNA-replication stress-response pathway
-
DOI 10.1016/S0962-8924(02)02380-2, PII S0962892402023802
-
Osborn AJ, Elledge SJ, Zou L. Checking on the fork: The DNA-replication stress-response pathway. Trends Cell Biol 2002; 12:509-16. (Pubitemid 35346701)
-
(2002)
Trends in Cell Biology
, vol.12
, Issue.11
, pp. 509-516
-
-
Osborn, A.J.1
Elledge, S.J.2
Zou, L.3
-
11
-
-
68249113593
-
Common mechanisms of PIKK regulation
-
Amst
-
Lovejoy CA, Cortez D. Common mechanisms of PIKK regulation. DNA Repair (Amst) 2009; 8:1004-8.
-
(2009)
DNA Repair
, vol.8
, pp. 1004-1008
-
-
Lovejoy, C.A.1
Cortez, D.2
-
12
-
-
35748967571
-
Rapid activation of ATM on DNA flanking double-strand breaks
-
DOI 10.1038/ncb1651, PII NCB1651
-
You Z, Bailis JM, Johnson SA, Dilworth SM, Hunter T. Rapid activation of ATM on DNA flanking double-strand breaks. Nat Cell Biol 2007; 9:1311-8. (Pubitemid 350042363)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.11
, pp. 1311-1318
-
-
You, Z.1
Bailis, J.M.2
Johnson, S.A.3
Dilworth, S.M.4
Hunter, T.5
-
13
-
-
5044236667
-
A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication
-
DOI 10.1038/sj.emboj.7600369
-
Pacek M, Walter JC. A requirement for MCM7 and Cdc45 in chromosome unwinding during eukaryotic DNA replication. EMBO J 2004; 23:3667-76. (Pubitemid 39336288)
-
(2004)
EMBO Journal
, vol.23
, Issue.18
, pp. 3667-3676
-
-
Pacek, M.1
Walter, J.C.2
-
14
-
-
18244371925
-
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint
-
DOI 10.1101/gad.1301205
-
Byun TS, Pacek M, Yee MC, Walter JC, Cimprich KA. Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint. Genes Dev 2005; 19:1040-52. (Pubitemid 40632450)
-
(2005)
Genes and Development
, vol.19
, Issue.9
, pp. 1040-1052
-
-
Byun, T.S.1
Pacek, M.2
Yee, M.-C.3
Walter, J.C.4
Cimprich, K.A.5
-
15
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
-
DOI 10.1126/science.1083430
-
Zou L, Elledge SJ. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 2003; 300:1542-8. (Pubitemid 36682880)
-
(2003)
Science
, vol.300
, Issue.5625
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
-
16
-
-
33644683073
-
Phosphorylation of Chk1 by ATM- And Rad3-related (ATR) in Xenopus egg extracts requires binding of ATRIP to ATR but not the stable DNA-binding or coiled-coil domains of ATRIP
-
DOI 10.1074/jbc.M508673200
-
Kim SM, Kumagai A, Lee J, Dunphy WG. Phosphorylation of Chk1 by ATM- and Rad3-related (ATR) in Xenopus egg extracts requires binding of ATRIP to ATR but not the stable DNA-binding or coiled-coil domains of ATRIP. J Biol Chem 2005; 280:38355-64. (Pubitemid 43853732)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.46
, pp. 38355-38364
-
-
Kim, S.-M.1
Kumagai, A.2
Lee, J.3
Dunphy, W.G.4
-
17
-
-
34147201111
-
The human Tim/Tipin complex coordinates an intra-S checkpoint response to UV that slows replication fork displacement
-
DOI 10.1128/MCB.02190-06
-
Unsal-Kacmaz K, Chastain PD, Qu PP, Minoo P, Cordeiro-Stone M, Sancar A, et al. The human Tim/ Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. Mol Cell Biol 2007; 27:3131-42. (Pubitemid 46581324)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.8
, pp. 3131-3142
-
-
Unsal-Kacmaz, K.1
Chastain, P.D.2
Qu, P.-P.3
Minoo, P.4
Cordeiro-Stone, M.5
Sancar, A.6
Kaufmann, W.K.7
-
18
-
-
0035941021
-
ATR and ATRIP: Partners in checkpoint signaling
-
DOI 10.1126/science.1065521
-
Cortez D, Guntuku S, Qin J, Elledge SJ. ATR and ATRIP: Partners in checkpoint signaling. Science 2001; 294:1713-6. (Pubitemid 33104841)
-
(2001)
Science
, vol.294
, Issue.5547
, pp. 1713-1716
-
-
Cortez, D.1
Guntuku, S.2
Qin, J.3
Elledge, S.J.4
-
19
-
-
0037080675
-
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin
-
DOI 10.1101/gad.950302
-
Zou L, Cortez D, Elledge SJ. Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin. Genes Dev 2002; 16:198-208. (Pubitemid 34075812)
-
(2002)
Genes and Development
, vol.16
, Issue.2
, pp. 198-208
-
-
Zou, L.1
Cortez, D.2
Elledge, S.J.3
-
20
-
-
77956375008
-
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
-
Choi JH, Lindsey-Boltz LA, Kemp M, Mason AC, Wold MS, Sancar A. Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling. Proc Natl Acad Sci USA 2010; 107:13660-5.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 13660-13665
-
-
Choi, J.H.1
Lindsey-Boltz, L.A.2
Kemp, M.3
Mason, A.C.4
Wold, M.S.5
Sancar, A.6
-
21
-
-
33344464960
-
ATM regulates ATR chromatin loading in response to DNA double-strand breaks
-
DOI 10.1084/jem.20051923
-
Cuadrado M, Martinez-Pastor B, Murga M, Toledo LI, Gutierrez-Martinez P, Lopez E, et al. ATM regulates ATR chromatin loading in response to DNA double-strand breaks. J Exp Med 2006; 203:297-303. (Pubitemid 43290838)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.2
, pp. 297-303
-
-
Cuadrado, M.1
Martinez-Pastor, B.2
Murga, M.3
Toledo, L.I.4
Gutierrez-Martinez, P.5
Lopez, E.6
Fernandez-Capetillo, O.7
-
22
-
-
33646777679
-
Rapid activation of ATR by ionizing radiation requires ATM and Mre11
-
DOI 10.1074/jbc.M513265200
-
Myers JS, Cortez D. Rapid activation of ATR by ionizing radiation requires ATM and Mre11. J Biol Chem 2006; 281:9346-50. (Pubitemid 43864651)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.14
, pp. 9346-9350
-
-
Myers, J.S.1
Cortez, D.2
-
23
-
-
30344463835
-
ATM- And cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
-
DOI 10.1038/ncb1337, PII N1337
-
Jazayeri A, Falck J, Lukas C, Bartek J, Smith GC, Lukas J, et al. ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks. Nat Cell Biol 2006; 8:37-45. (Pubitemid 43064795)
-
(2006)
Nature Cell Biology
, vol.8
, Issue.1
, pp. 37-45
-
-
Jazayeri, A.1
Falck, J.2
Lukas, C.3
Bartek, J.4
Smith, G.C.M.5
Lukas, J.6
Jackson, S.P.7
-
24
-
-
35648986560
-
Ctp1/CtIP and the MRN Complex Collaborate in the Initial Steps of Homologous Recombination
-
DOI 10.1016/j.molcel.2007.10.016, PII S1097276507006983
-
Takeda S, Nakamura K, Taniguchi Y, Paull TT. Ctp1/ CtIP and the MRN complex collaborate in the initial steps of homologous recombination. Mol Cell 2007; 28:351-2. (Pubitemid 350030570)
-
(2007)
Molecular Cell
, vol.28
, Issue.3
, pp. 351-352
-
-
Takeda, S.1
Nakamura, K.2
Taniguchi, Y.3
Paull, T.T.4
-
25
-
-
36549060102
-
Human CtIP promotes DNA end resection
-
DOI 10.1038/nature06337
-
Sartori AA, Lukas C, Coates J, Mistrik M, Fu S, Bartek J, et al. Human CtIP promotes DNA end resection. Nature 2007; 450:509-14. (Pubitemid 350190253)
-
(2007)
Nature
, vol.450
, Issue.7169
, pp. 509-514
-
-
Sartori, A.A.1
Lukas, C.2
Coates, J.3
Mistrik, M.4
Fu, S.5
Bartek, J.6
Baer, R.7
Lukas, J.8
Jackson, S.P.9
-
26
-
-
34147201111
-
The human Tim/Tipin complex coordinates an intra-S checkpoint response to UV that slows replication fork displacement
-
DOI 10.1128/MCB.02190-06
-
Unsal-Kacmaz K, Chastain PD, Qu PP, Minoo P, Cordeiro-Stone M, Sancar A, et al. The human Tim/ Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. Mol Cell Biol 2007; 27:3131-42. (Pubitemid 46581324)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.8
, pp. 3131-3142
-
-
Unsal-Kacmaz, K.1
Chastain, P.D.2
Qu, P.-P.3
Minoo, P.4
Cordeiro-Stone, M.5
Sancar, A.6
Kaufmann, W.K.7
-
27
-
-
0033634679
-
Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts
-
Kumagai A, Dunphy WG. Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts. Mol Cell 2000; 6:839-49.
-
(2000)
Mol Cell
, vol.6
, pp. 839-849
-
-
Kumagai, A.1
Dunphy, W.G.2
-
28
-
-
0043032435
-
Human claspin is required for replication checkpoint control
-
DOI 10.1074/jbc.M301136200
-
Chini CC, Chen J. Human claspin is required for replication checkpoint control. J Biol Chem 2003; 278:30057-62. (Pubitemid 36962397)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.32
, pp. 30057-30062
-
-
Christiano, C.1
Chini, S.2
Chen, J.3
-
29
-
-
33644757806
-
TopBP1 activates the ATR-ATRIP complex
-
DOI 10.1016/j.cell.2005.12.041, PII S0092867406001723
-
Kumagai A, Lee J, Yoo HY, Dunphy WG. TopBP1 activates the ATR-ATRIP complex. Cell 2006; 124:943-55. (Pubitemid 43344235)
-
(2006)
Cell
, vol.124
, Issue.5
, pp. 943-955
-
-
Kumagai, A.1
Lee, J.2
Yoo, H.Y.3
Dunphy, W.G.4
-
30
-
-
33746408535
-
Rad17 Phosphorylation Is Required for Claspin Recruitment and Chk1 Activation in Response to Replication Stress
-
DOI 10.1016/j.molcel.2006.06.022, PII S1097276506004497
-
Wang X, Zou L, Lu T, Bao S, Hurov KE, Hittelman WN, et al. Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress. Mol Cell 2006; 23:331-41. (Pubitemid 44128854)
-
(2006)
Molecular Cell
, vol.23
, Issue.3
, pp. 331-341
-
-
Wang, X.1
Zou, L.2
Lu, T.3
Bao, S.4
Hurov, K.E.5
Hittelman, W.N.6
Elledge, S.J.7
Li, L.8
-
31
-
-
34250705797
-
The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1
-
DOI 10.1101/gad.1547007
-
Delacroix S, Wagner JM, Kobayashi M, Yamamoto K, Karnitz LM. The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1. Genes Dev 2007; 21:1472-7. (Pubitemid 46955719)
-
(2007)
Genes and Development
, vol.21
, Issue.12
, pp. 1472-1477
-
-
Delacroix, S.1
Wagner, J.M.2
Kobayashi, M.3
Yamamoto, K.-I.4
Karnitz, L.M.5
-
32
-
-
0034967556
-
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
-
DOI 10.1128/MCB.21.13.4129-4139.2001
-
Zhao H, Piwnica-Worms H. ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol Cell Biol 2001; 21:4129-39. (Pubitemid 32565295)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.13
, pp. 4129-4139
-
-
Zhao, H.1
Piwnica-Worms, H.2
-
33
-
-
17644432403
-
Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint
-
Liu Q, Guntuku S, Cui XS, Matsuoka S, Cortez D, Tamai K, et al. Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint. Genes Dev 2000; 14:1448-59.
-
(2000)
Genes Dev
, vol.14
, pp. 1448-1459
-
-
Liu, Q.1
Guntuku, S.2
Cui, X.S.3
Matsuoka, S.4
Cortez, D.5
Tamai, K.6
-
34
-
-
68249092083
-
Studying the DNA damage response using in vitro model systems
-
Garner E, Costanzo V. Studying the DNA damage response using in vitro model systems. DNA Repair 2009; 8:1025-37.
-
(2009)
DNA Repair
, vol.8
, pp. 1025-1037
-
-
Garner, E.1
Costanzo, V.2
-
35
-
-
20544478438
-
DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system
-
DOI 10.1042/BJ20041966
-
Clarke CA, Clarke PR. DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system. Biochem J 2005; 388:705-12. (Pubitemid 40839948)
-
(2005)
Biochemical Journal
, vol.388
, Issue.2
, pp. 705-712
-
-
Clarke, C.A.L.1
Clarke, P.R.2
-
36
-
-
61649093808
-
Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks
-
Shiotani B, Zou L. Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks. Mol Cell 2009; 33:547-58.
-
(2009)
Mol Cell
, vol.33
, pp. 547-558
-
-
Shiotani, B.1
Zou, L.2
-
37
-
-
68949221708
-
The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress
-
Zhang YW, Brognard J, Coughlin C, You Z, Dolled-Filhart M, Aslanian A, et al. The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress. Mol Cell 2009; 35:442-53.
-
(2009)
Mol Cell
, vol.35
, pp. 442-453
-
-
Zhang, Y.W.1
Brognard, J.2
Coughlin, C.3
You, Z.4
Dolled-Filhart, M.5
Aslanian, A.6
-
38
-
-
1842431822
-
Direct Activation of the ATM Protein Kinase by the Mre11/Rad50/Nbs1 Complex
-
DOI 10.1126/science.1091496
-
Lee JH, Paull TT. Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex. Science 2004; 304:93-6. (Pubitemid 38451463)
-
(2004)
Science
, vol.304
, Issue.5667
, pp. 93-96
-
-
Lee, J.-H.1
Paull, T.T.2
-
39
-
-
65649106718
-
The human ATR-mediated DNA damage checkpoint in a reconstituted system
-
Choi JH, Sancar A, Lindsey-Boltz LA. The human ATR-mediated DNA damage checkpoint in a reconstituted system. Methods 2009; 48:3-7.
-
(2009)
Methods
, vol.48
, pp. 3-7
-
-
Choi, J.H.1
Sancar, A.2
Lindsey-Boltz, L.A.3
-
40
-
-
77956375008
-
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
-
Choi JH, Lindsey-Boltz LA, Kemp M, Mason AC, Wold MS, Sancar A. Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling. Proc Natl Acad Sci USA 2010; 107:13660-5.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 13660-13665
-
-
Choi, J.H.1
Lindsey-Boltz, L.A.2
Kemp, M.3
Mason, A.C.4
Wold, M.S.5
Sancar, A.6
-
41
-
-
0033199892
-
Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine
-
Sarkaria JN, Busby EC, Tibbetts RS, Roos P, Taya Y, Karnitz LM, et al. Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. Cancer Res 1999; 59:4375-82. (Pubitemid 29418757)
-
(1999)
Cancer Research
, vol.59
, Issue.17
, pp. 4375-4382
-
-
Sarkaria, J.N.1
Busby, E.C.2
Tibbetts, R.S.3
Roos, P.4
Taya, Y.5
Karnitz, L.M.6
Abraham, R.T.7
-
42
-
-
24044476837
-
Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway
-
DOI 10.1016/j.molcel.2005.07.019, PII S1097276505015078
-
Zhang YW, Otterness DM, Chiang GG, Xie W, Liu YC, Mercurio F, et al. Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway. Mol Cell 2005; 19:607-18. (Pubitemid 41219437)
-
(2005)
Molecular Cell
, vol.19
, Issue.5
, pp. 607-618
-
-
Zhang, Y.-W.1
Otterness, D.M.2
Chiang, G.G.3
Xie, W.4
Liu, Y.-C.5
Mercurio, F.6
Abraham, R.T.7
-
43
-
-
34147206546
-
Specific role of Chk1 phosphorylations in cell survival and checkpoint activation
-
DOI 10.1128/MCB.01611-06
-
Niida H, Katsuno Y, Banerjee B, Hande MP, Nakanishi M. Specific role of Chk1 phosphorylations in cell survival and checkpoint activation. Mol Cell Biol 2007; 27:2572-81. (Pubitemid 46581348)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.7
, pp. 2572-2581
-
-
Niida, H.1
Katsuno, Y.2
Banerjee, B.3
Hande, M.P.4
Nakanishi, M.5
-
44
-
-
58549089689
-
Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control
-
Wilsker D, Petermann E, Helleday T, Bunz F. Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control. Proc Natl Acad Sci USA 2008; 105:20752-7.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20752-20757
-
-
Wilsker, D.1
Petermann, E.2
Helleday, T.3
Bunz, F.4
-
45
-
-
67649253108
-
Chk1 C-terminal regulatory phosphorylation mediates checkpoint activation by de-repression of Chk1 catalytic activity
-
Walker M, Black EJ, Oehler V, Gillespie DA, Scott MT. Chk1 C-terminal regulatory phosphorylation mediates checkpoint activation by de-repression of Chk1 catalytic activity. Oncogene 2009; 28:2314-23.
-
(2009)
Oncogene
, vol.28
, pp. 2314-2323
-
-
Walker, M.1
Black, E.J.2
Oehler, V.3
Gillespie, D.A.4
Scott, M.T.5
-
46
-
-
63249115140
-
Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA
-
Choi JH, Lindsey-Boltz LA, Sancar A. Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA. Nucleic Acids Res 2009; 37:1501-9.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 1501-1509
-
-
Choi, J.H.1
Lindsey-Boltz, L.A.2
Sancar, A.3
-
47
-
-
0035927713
-
ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic responses
-
DOI 10.1038/35082110
-
Bao S, Tibbetts RS, Brumbaugh KM, Fang Y, Richardson DA, Ali A, et al. ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses. Nature 2001; 411:969-74. (Pubitemid 32601496)
-
(2001)
Nature
, vol.411
, Issue.6840
, pp. 969-974
-
-
Bao, S.1
Tibbetts, R.S.2
Brumbaugh, K.M.3
Fang, Y.4
Richardson, D.A.5
Ali, A.6
Chen, S.M.7
Abraham, R.T.8
Wang, X.-F.9
-
48
-
-
0037472924
-
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
-
DOI 10.1038/nature01368
-
Bakkenist CJ, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 2003; 421:499-506. (Pubitemid 36168436)
-
(2003)
Nature
, vol.421
, Issue.6922
, pp. 499-506
-
-
Bakkenist, C.J.1
Kastan, M.B.2
-
49
-
-
53349156857
-
Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1
-
Blasina A, Hallin J, Chen E, Arango ME, Kraynov E, Register J, et al. Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1. Mol Cancer Ther 2008; 7:2394-404.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 2394-2404
-
-
Blasina, A.1
Hallin, J.2
Chen, E.3
Arango, M.E.4
Kraynov, E.5
Register, J.6
-
50
-
-
13944274948
-
The past, present and future of cell-free protein synthesis
-
DOI 10.1016/j.tibtech.2005.01.003, PII S0167779905000259
-
Katzen F, Chang G, Kudlicki W. The past, present and future of cell-free protein synthesis. Trends Biotechnol 2005; 23:150-6. (Pubitemid 40269848)
-
(2005)
Trends in Biotechnology
, vol.23
, Issue.3
, pp. 150-156
-
-
Katzen, F.1
Chang, G.2
Kudlicki, W.3
-
51
-
-
0036258583
-
Chk2 activation and pho sphorylation-dependent oligomerization
-
Xu X, Tsvetkov LM, Stern DF. Chk2 activation and pho sphorylation- dependent oligomerization. Mol Cell Biol 2002; 22:4419-32.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4419-4432
-
-
Xu, X.1
Tsvetkov, L.M.2
Stern, D.F.3
-
52
-
-
15744386741
-
Regulation of CHK2 by DNA-dependent protein kinase
-
DOI 10.1074/jbc.M412445200
-
Li J, Stern DF. Regulation of CHK2 by DNA-dependent protein kinase. J Biol Chem 2005; 280:12041-50. (Pubitemid 40418523)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.12
, pp. 12041-12050
-
-
Li, J.1
Stern, D.F.2
-
53
-
-
2942572923
-
The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells
-
DOI 10.1016/j.molcel.2004.05.005, PII S1097276504002722
-
Brumbaugh KM, Otterness DM, Geisen C, Oliveira V, Brognard J, Li X, et al. The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells. Mol Cell 2004; 14:585-98. (Pubitemid 38739082)
-
(2004)
Molecular Cell
, vol.14
, Issue.5
, pp. 585-598
-
-
Brumbaugh, K.M.1
Otterness, D.M.2
Geisen, C.3
Oliveira, V.4
Brognard, J.5
Li, X.6
Lejeune, F.7
Tibbetts, R.S.8
Maquat, L.E.9
Abraham, R.T.10
|