Rad17 Phosphorylation Is Required for Claspin Recruitment and Chk1 Activation in Response to Replication Stress

Molecular Cell

Volumn 23, Issue 3, 2006, Pages 331-341

  Wang, Xin ^a   Zou, Lee ^b   Lu, Tao ^a   Bao, Shilai ^a   Hurov, Kristen E ^c   Hittelman, Walter N ^a   Elledge, Stephen J ^c   Li, Lei ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

CELLCYCLE; DNA

Indexed keywords

ATR PROTEIN; CHECKPOINT KINASE 1; CLASPIN; HYDROXYUREA; MUTANT PROTEIN; PROTEIN; RAD17 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA REPLICATION; ENZYME ACTIVATION; GENOMIC INSTABILITY; GENOTOXICITY; HUMAN; HUMAN CELL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; ULTRAVIOLET RADIATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CHROMATIN; DNA DAMAGE; DNA REPLICATION; GENOMIC INSTABILITY; HCT116 CELLS; HISTONES; HUMANS; HYDROXYUREA; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; S PHASE; TRANSFECTION; ULTRAVIOLET RAYS;

EID: 33746408535     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2006.06.022     Document Type: Article

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