Redox regulation of mitochondrial fission, protein misfolding, synaptic damage, and neuronal cell death: Potential implications for Alzheimer's and Parkinson's diseases

Apoptosis

Volumn 15, Issue 11, 2010, Pages 1354-1363

  Nakamura, Tomohiro ^a   Lipton, Stuart A ^a,b  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Amyloid; Alzheimer's disease; Dynamin related protein 1; Mitochondrial fragmentation; S Nitrosylation

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; AMYLOID BETA PROTEIN; BETA SECRETASE; CYCLIC GMP; DYNAMIN RELATED PROTEIN 1; GAMMA SECRETASE; GLUTAMATE RECEPTOR; GUANOSINE TRIPHOSPHATASE; MITOCHONDRIAL PROTEIN; MITOFUSIN 1; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE; OLIGOMER; PARKIN; REACTIVE OXYGEN METABOLITE; TAU PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; BIOGENESIS; CELL DEATH; DEMENTIA; DIFFUSE LEWY BODY DISEASE; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; GENE INTERACTION; GENE MUTATION; HUMAN; LEWY BODY; MEMBRANE FUSION; MITOCHONDRION; MOLECULAR DYNAMICS; MORPHOLOGY; NERVE CELL; NERVE CELL LESION; NEUROFIBRILLARY TANGLE; NEUROTOXICITY; NEUROTRANSMISSION; NITROSATIVE STRESS; NITROSYLATION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN MISFOLDING; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; PROTEIN TARGETING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SYNAPSE; SYNAPTIC MEMBRANE;

ALZHEIMER DISEASE; ANIMALS; APOPTOSIS; HUMANS; MITOCHONDRIA; NEURONS; NITRIC OXIDE; OXIDATION-REDUCTION; PARKINSON DISEASE; PROTEIN FOLDING; PROTEINS;

ANIMALIA;

EID: 78649983205     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-010-0476-x     Document Type: Article

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