The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity

Journal of Neuroscience

Volumn 25, Issue 11, 2005, Pages 2793-2802

  Hetz, Claudio ^a,b   Russelakis Carneiro, Milene ^a   Wälchli, Sébastien ^c   Carboni, Sonia ^a   Vial Knecht, Elisabeth ^a   Maundrell, Kinsey ^a   Castilla, Joaquín ^d   Soto, Claudio ^a,d  

^a SERONO PHARMACEUTICAL RES INSTITUTE   (Switzerland)

^b UNIVERSITY OF CHILE   (Chile)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

^d University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Apoptosis; Caspase 12; Endoplasmic reticulum stress; Grp58; Prion; Scrapie; Transmissible spongiform encephalopathy

Indexed keywords

CASPASE 12; CHAPERONE; DISULFIDE; GLUCOSE REGULATED PROTEIN; GLUCOSE REGULATED PROTEIN 58; ISOMERASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME INHIBITION; IMMUNOPRECIPITATION; MOUSE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRION; PRION DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCRAPIE; UPREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; ANTI-BACTERIAL AGENTS; BLOTTING, WESTERN; BRAIN; CALCIMYCIN; CALCIUM SIGNALING; CARCINOMA; CELL LINE, TUMOR; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; PHOSPHOPYRUVATE HYDRATASE; PRION DISEASES; PRIONS; PROTEIN DISULFIDE-ISOMERASE; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 15244361681     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4090-04.2005     Document Type: Article

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