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Volumn 18, Issue 4, 2006, Pages 453-459

Critical dependence of neurons on mitochondrial dynamics

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM;

EID: 33745757783     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ceb.2006.06.004     Document Type: Review
Times cited : (190)

References (52)
  • 1
    • 20344366079 scopus 로고    scopus 로고
    • Mitochondrial DNA and disease
    • Dimauro S., and Davidzon G. Mitochondrial DNA and disease. Ann Med 37 (2005) 222-232
    • (2005) Ann Med , vol.37 , pp. 222-232
    • Dimauro, S.1    Davidzon, G.2
  • 2
    • 17744393686 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in human disease
    • This comprehensive review of mtDNA disease covers mitochondrial genetics, clinical features, cellular and animal models, and mtDNA involvement in aging and cancer.
    • Taylor R.W., and Turnbull D.M. Mitochondrial DNA mutations in human disease. Nat Rev Genet 6 (2005) 389-402. This comprehensive review of mtDNA disease covers mitochondrial genetics, clinical features, cellular and animal models, and mtDNA involvement in aging and cancer.
    • (2005) Nat Rev Genet , vol.6 , pp. 389-402
    • Taylor, R.W.1    Turnbull, D.M.2
  • 3
    • 25444474703 scopus 로고    scopus 로고
    • Mitochondria take center stage in aging and neurodegeneration
    • Beal M.F. Mitochondria take center stage in aging and neurodegeneration. Ann Neurol 58 (2005) 495-505
    • (2005) Ann Neurol , vol.58 , pp. 495-505
    • Beal, M.F.1
  • 5
    • 77049268148 scopus 로고
    • Synapses in the central nervous system
    • Palay S.L. Synapses in the central nervous system. J Biophys Biochem Cytol 2 (1956) 193-202
    • (1956) J Biophys Biochem Cytol , vol.2 , pp. 193-202
    • Palay, S.L.1
  • 6
    • 10944269186 scopus 로고    scopus 로고
    • The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses
    • Dendritic development in rat hippocampal cells correlates with mitochondrial movement into dendritic protrusions, implying a requirement for mitochondria in developing dendrites.
    • Li Z., Okamoto K., Hayashi Y., and Sheng M. The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell 119 (2004) 873-887. Dendritic development in rat hippocampal cells correlates with mitochondrial movement into dendritic protrusions, implying a requirement for mitochondria in developing dendrites.
    • (2004) Cell , vol.119 , pp. 873-887
    • Li, Z.1    Okamoto, K.2    Hayashi, Y.3    Sheng, M.4
  • 7
    • 0037137704 scopus 로고    scopus 로고
    • Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein
    • Stowers R.S., Megeath L.J., Gorska-Andrzejak J., Meinertzhagen I.A., and Schwarz T.L. Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein. Neuron 36 (2002) 1063-1077
    • (2002) Neuron , vol.36 , pp. 1063-1077
    • Stowers, R.S.1    Megeath, L.J.2    Gorska-Andrzejak, J.3    Meinertzhagen, I.A.4    Schwarz, T.L.5
  • 8
    • 23044432581 scopus 로고    scopus 로고
    • The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses
    • dMiro is required for axonal transport of mitochondria. Mutants exhibit irregular synaptic boutons at neuromuscular junctions, locomotor defects, and early lethality. Strikingly, neuronal, but not muscular expression of dMiro rescues all of these defects.
    • Guo X., Macleod G.T., Wellington A., Hu F., Panchumarthi S., Schoenfield M., Marin L., Charlton M.P., Atwood H.L., and Zinsmaier K.E. The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses. Neuron 47 (2005) 379-393. dMiro is required for axonal transport of mitochondria. Mutants exhibit irregular synaptic boutons at neuromuscular junctions, locomotor defects, and early lethality. Strikingly, neuronal, but not muscular expression of dMiro rescues all of these defects.
    • (2005) Neuron , vol.47 , pp. 379-393
    • Guo, X.1    Macleod, G.T.2    Wellington, A.3    Hu, F.4    Panchumarthi, S.5    Schoenfield, M.6    Marin, L.7    Charlton, M.P.8    Atwood, H.L.9    Zinsmaier, K.E.10
  • 10
    • 27744491193 scopus 로고    scopus 로고
    • Emerging functions of mammalian mitochondrial fusion and fission
    • This review covers molecular mechanisms, cellular functions, and pathophysiological consequences of mitochondrial dynamics in mammals.
    • Chen H., and Chan D.C. Emerging functions of mammalian mitochondrial fusion and fission. Hum Mol Genet 14 (2005) R283-R289. This review covers molecular mechanisms, cellular functions, and pathophysiological consequences of mitochondrial dynamics in mammals.
    • (2005) Hum Mol Genet , vol.14
    • Chen, H.1    Chan, D.C.2
  • 11
    • 0037455575 scopus 로고    scopus 로고
    • Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
    • Chen H., Detmer S.A., Ewald A.J., Griffin E.E., Fraser S.E., and Chan D.C. Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J Cell Biol 160 (2003) 189-200
    • (2003) J Cell Biol , vol.160 , pp. 189-200
    • Chen, H.1    Detmer, S.A.2    Ewald, A.J.3    Griffin, E.E.4    Fraser, S.E.5    Chan, D.C.6
  • 12
    • 0037089084 scopus 로고    scopus 로고
    • Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo
    • Rojo M., Legros F., Chateau D., and Lombes A. Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo. J Cell Sci 115 (2002) 1663-1674
    • (2002) J Cell Sci , vol.115 , pp. 1663-1674
    • Rojo, M.1    Legros, F.2    Chateau, D.3    Lombes, A.4
  • 13
    • 0035057837 scopus 로고    scopus 로고
    • Control of mitochondrial morphology by a human mitofusin
    • Santel A., and Fuller M.T. Control of mitochondrial morphology by a human mitofusin. J Cell Sci 114 (2001) 867-874
    • (2001) J Cell Sci , vol.114 , pp. 867-874
    • Santel, A.1    Fuller, M.T.2
  • 15
    • 22544451586 scopus 로고    scopus 로고
    • Disruption of fusion results in mitochondrial heterogeneity and dysfunction
    • Mitochondrial fusion mutants display respiratory and cell growth defects, indicating a role for fusion beyond that of mere morphology maintenance.
    • Chen H., Chomyn A., and Chan D.C. Disruption of fusion results in mitochondrial heterogeneity and dysfunction. J Biol Chem 280 (2005) 26185-26192. Mitochondrial fusion mutants display respiratory and cell growth defects, indicating a role for fusion beyond that of mere morphology maintenance.
    • (2005) J Biol Chem , vol.280 , pp. 26185-26192
    • Chen, H.1    Chomyn, A.2    Chan, D.C.3
  • 17
    • 2442421118 scopus 로고    scopus 로고
    • Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria
    • Griparic L., van der Wel N.N., Orozco I.J., Peters P.J., and van der Bliek A.M. Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria. J Biol Chem 279 (2004) 18792-18798
    • (2004) J Biol Chem , vol.279 , pp. 18792-18798
    • Griparic, L.1    van der Wel, N.N.2    Orozco, I.J.3    Peters, P.J.4    van der Bliek, A.M.5
  • 19
    • 0037427529 scopus 로고    scopus 로고
    • Differential sublocalization of the dynamin-related protein OPA1 isoforms in mitochondria
    • Satoh M., Hamamoto T., Seo N., Kagawa Y., and Endo H. Differential sublocalization of the dynamin-related protein OPA1 isoforms in mitochondria. Biochem Biophys Res Commun 300 (2003) 482-493
    • (2003) Biochem Biophys Res Commun , vol.300 , pp. 482-493
    • Satoh, M.1    Hamamoto, T.2    Seo, N.3    Kagawa, Y.4    Endo, H.5
  • 20
    • 6344274848 scopus 로고    scopus 로고
    • Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis
    • Lee Y.J., Jeong S.Y., Karbowski M., Smith C.L., and Youle R.J. Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis. Mol Biol Cell 15 (2004) 5001-5011
    • (2004) Mol Biol Cell , vol.15 , pp. 5001-5011
    • Lee, Y.J.1    Jeong, S.Y.2    Karbowski, M.3    Smith, C.L.4    Youle, R.J.5
  • 21
    • 0035166814 scopus 로고    scopus 로고
    • Dynamin-related protein drp1 is required for mitochondrial division in mammalian cells
    • Smirnova E., Griparic L., Shurland D.L., and van Der Bliek A.M. Dynamin-related protein drp1 is required for mitochondrial division in mammalian cells. Mol Biol Cell 12 (2001) 2245-2256
    • (2001) Mol Biol Cell , vol.12 , pp. 2245-2256
    • Smirnova, E.1    Griparic, L.2    Shurland, D.L.3    van Der Bliek, A.M.4
  • 22
    • 2142758117 scopus 로고    scopus 로고
    • Mitochondrial dynamics in mammals
    • Chen H., and Chan D.C. Mitochondrial dynamics in mammals. Curr Top Dev Biol 59 (2004) 119-144
    • (2004) Curr Top Dev Biol , vol.59 , pp. 119-144
    • Chen, H.1    Chan, D.C.2
  • 23
  • 24
    • 0037424239 scopus 로고    scopus 로고
    • Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
    • Olichon A., Baricault L., Gas N., Guillou E., Valette A., Belenguer P., and Lenaers G. Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis. J Biol Chem 278 (2003) 7743-7746
    • (2003) J Biol Chem , vol.278 , pp. 7743-7746
    • Olichon, A.1    Baricault, L.2    Gas, N.3    Guillou, E.4    Valette, A.5    Belenguer, P.6    Lenaers, G.7
  • 25
    • 10644296253 scopus 로고    scopus 로고
    • Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis
    • Sugioka R., Shimizu S., and Tsujimoto Y. Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis. J Biol Chem 279 (2004) 52726-52734
    • (2004) J Biol Chem , vol.279 , pp. 52726-52734
    • Sugioka, R.1    Shimizu, S.2    Tsujimoto, Y.3
  • 27
    • 22544465572 scopus 로고    scopus 로고
    • Clinical and electrophysiologic features of CMT2A with mutations in the mitofusin 2 gene
    • Lawson V.H., Graham B.V., and Flanigan K.M. Clinical and electrophysiologic features of CMT2A with mutations in the mitofusin 2 gene. Neurology 65 (2005) 197-204
    • (2005) Neurology , vol.65 , pp. 197-204
    • Lawson, V.H.1    Graham, B.V.2    Flanigan, K.M.3
  • 28
    • 2442589922 scopus 로고    scopus 로고
    • Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A
    • This genetic study provided the original identification of Mfn2 as the predominant gene causing CMT2A.
    • Zuchner S., Mersiyanova I.V., Muglia M., Bissar-Tadmouri N., Rochelle J., Dadali E.L., Zappia M., Nelis E., Patitucci A., Senderek J., et al. Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A. Nat Genet 36 (2004) 449-451. This genetic study provided the original identification of Mfn2 as the predominant gene causing CMT2A.
    • (2004) Nat Genet , vol.36 , pp. 449-451
    • Zuchner, S.1    Mersiyanova, I.V.2    Muglia, M.3    Bissar-Tadmouri, N.4    Rochelle, J.5    Dadali, E.L.6    Zappia, M.7    Nelis, E.8    Patitucci, A.9    Senderek, J.10
  • 29
    • 6944246275 scopus 로고    scopus 로고
    • Charcot-Marie-Tooth disease: an update
    • Shy M.E. Charcot-Marie-Tooth disease: an update. Curr Opin Neurol 17 (2004) 579-585
    • (2004) Curr Opin Neurol , vol.17 , pp. 579-585
    • Shy, M.E.1
  • 30
    • 0346100497 scopus 로고    scopus 로고
    • The causes of Charcot-Marie-Tooth disease
    • Young P., and Suter U. The causes of Charcot-Marie-Tooth disease. Cell Mol Life Sci 60 (2003) 2547-2560
    • (2003) Cell Mol Life Sci , vol.60 , pp. 2547-2560
    • Young, P.1    Suter, U.2
  • 34
    • 25444514731 scopus 로고    scopus 로고
    • Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease
    • GDAP1, a gene mutated in CMT4A, influences mitochondrial fission. Therefore, yet another neurodegenerative disease may have a primary defect in mitochondrial dynamics.
    • Niemann A., Ruegg M., La Padula V., Schenone A., and Suter U. Ganglioside-induced differentiation associated protein 1 is a regulator of the mitochondrial network: new implications for Charcot-Marie-Tooth disease. J Cell Biol 170 (2005) 1067-1078. GDAP1, a gene mutated in CMT4A, influences mitochondrial fission. Therefore, yet another neurodegenerative disease may have a primary defect in mitochondrial dynamics.
    • (2005) J Cell Biol , vol.170 , pp. 1067-1078
    • Niemann, A.1    Ruegg, M.2    La Padula, V.3    Schenone, A.4    Suter, U.5
  • 44
    • 15244364005 scopus 로고    scopus 로고
    • Mitochondrial DNA content is decreased in autosomal dominant optic atrophy
    • Kim J.Y., Hwang J.M., Ko H.S., Seong M.W., Park B.J., and Park S.S. Mitochondrial DNA content is decreased in autosomal dominant optic atrophy. Neurology 64 (2005) 966-972
    • (2005) Neurology , vol.64 , pp. 966-972
    • Kim, J.Y.1    Hwang, J.M.2    Ko, H.S.3    Seong, M.W.4    Park, B.J.5    Park, S.S.6
  • 46
    • 0035205389 scopus 로고    scopus 로고
    • Type III 3-methylglutaconic aciduria (optic atrophy plus syndrome, or Costeff optic atrophy syndrome): identification of the OPA3 gene and its founder mutation in Iraqi Jews
    • Anikster Y., Kleta R., Shaag A., Gahl W.A., and Elpeleg O. Type III 3-methylglutaconic aciduria (optic atrophy plus syndrome, or Costeff optic atrophy syndrome): identification of the OPA3 gene and its founder mutation in Iraqi Jews. Am J Hum Genet 69 (2001) 1218-1224
    • (2001) Am J Hum Genet , vol.69 , pp. 1218-1224
    • Anikster, Y.1    Kleta, R.2    Shaag, A.3    Gahl, W.A.4    Elpeleg, O.5
  • 47
    • 0842281697 scopus 로고    scopus 로고
    • Mitochondrial dysfunction as a cause of optic neuropathies
    • The relationship between mitochondria and optic neuropathy is explored in this review, with emphasis on basic biology, LHON and DOA, animal models, and possible therapies.
    • Carelli V., Ross-Cisneros F.N., and Sadun A.A. Mitochondrial dysfunction as a cause of optic neuropathies. Prog Retin Eye Res 23 (2004) 53-89. The relationship between mitochondria and optic neuropathy is explored in this review, with emphasis on basic biology, LHON and DOA, animal models, and possible therapies.
    • (2004) Prog Retin Eye Res , vol.23 , pp. 53-89
    • Carelli, V.1    Ross-Cisneros, F.N.2    Sadun, A.A.3
  • 48
    • 0027371282 scopus 로고
    • Axoplasmic organelles at nodes of Ranvier. II. Occurrence and distribution in large myelinated spinal cord axons of the adult cat
    • Fabricius C., Berthold C.H., and Rydmark M. Axoplasmic organelles at nodes of Ranvier. II. Occurrence and distribution in large myelinated spinal cord axons of the adult cat. J Neurocytol 22 (1993) 941-954
    • (1993) J Neurocytol , vol.22 , pp. 941-954
    • Fabricius, C.1    Berthold, C.H.2    Rydmark, M.3
  • 49
    • 5444276493 scopus 로고    scopus 로고
    • Mitochondrial accumulation in the distal part of the initial segment of chicken spinal motoneurons
    • Li Y.C., Zhai X.Y., Ohsato K., Futamata H., Shimada O., and Atsumi S. Mitochondrial accumulation in the distal part of the initial segment of chicken spinal motoneurons. Brain Res 1026 (2004) 235-243
    • (2004) Brain Res , vol.1026 , pp. 235-243
    • Li, Y.C.1    Zhai, X.Y.2    Ohsato, K.3    Futamata, H.4    Shimada, O.5    Atsumi, S.6
  • 50
    • 0022349766 scopus 로고
    • Localization of sodium/potassium adenosine triphosphatase in multiple cell types of the murine nervous system with antibodies raised against the enzyme from kidney
    • Ariyasu R.G., Nichol J.A., and Ellisman M.H. Localization of sodium/potassium adenosine triphosphatase in multiple cell types of the murine nervous system with antibodies raised against the enzyme from kidney. J Neurosci 5 (1985) 2581-2596
    • (1985) J Neurosci , vol.5 , pp. 2581-2596
    • Ariyasu, R.G.1    Nichol, J.A.2    Ellisman, M.H.3
  • 51
    • 0031822283 scopus 로고    scopus 로고
    • Focal accumulation of intra-axonal mitochondria in demyelination of the cat optic nerve
    • Mutsaers S.E., and Carroll W.M. Focal accumulation of intra-axonal mitochondria in demyelination of the cat optic nerve. Acta Neuropathol (Berl) 96 (1998) 139-143
    • (1998) Acta Neuropathol (Berl) , vol.96 , pp. 139-143
    • Mutsaers, S.E.1    Carroll, W.M.2
  • 52
    • 27544466847 scopus 로고    scopus 로고
    • Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes
    • Okamoto K., and Shaw J.M. Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes. Annu Rev Genet 39 (2005) 503-536
    • (2005) Annu Rev Genet , vol.39 , pp. 503-536
    • Okamoto, K.1    Shaw, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.