Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 10, 1996, Pages 4565-4571

  Przedborski, Serge ^a   Jackson Lewis, Vernice ^a   Yokoyama, Rina ^a   Shibata, Toshihiro ^b   Dawson, Valina L ^b   Dawson, Ted M ^b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Nitric oxide synthase; Parkinson disease; Superoxide dismutase; Superoxide radical

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DISEASE SEVERITY; DOPAMINERGIC SYSTEM; HISTOPATHOLOGY; MALE; MAMMAL; MOUSE; NERVE CELL LESION; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL;

3,4-DIHYDROXYPHENYLACETIC ACID; ANIMALS; CEREBELLUM; CORPUS STRIATUM; DOPAMINE; DOPAMINE AGENTS; ENZYME INHIBITORS; HOMOVANILLIC ACID; HUMANS; INDAZOLES; ISOENZYMES; MALE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MPTP POISONING; NERVE DEGENERATION; NEURONS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PARKINSON DISEASE; SUBSTANTIA NIGRA;

EID: 0029984860     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.10.4565     Document Type: Article

References (57)

1. Langston, J. W. & Irwin, I. (1986) Clin. Neuropharmacol. 9, 485-507.
2. Heikkila, R. E., Sieber, B. A., Manzino, L. & Sonsalla, P. K. (1989) Mol. Chem. Neuropathol. 10, 171-183.
3. Kopin, I. J. & Markey, S. P. (1988) Annu. Rev. Neurosci. 11, 81-96.
4. Fahn, S. (1988) in Parkinsonism, eds. Wyngaarden, J. B. & Smith, L. H., Jr. (Saunders, Philadelphia), Vol. 18, pp. 2143-2147.
5. Jenner, P., Schapira, A. H. V. & Marsden, C. D. (1992) Neurology 42, 2241-2250.
6. Jackson-Lewis, V., Jakowec, M., Burke, R. E. & Przedborski, S. (1995) Neurodegeneration 4, 257-269.
7. Forno, L. S., DeLanney, L. E., Irwin, I. & Langston, J. W. (1993) Adv. Neurol. 60, 600-608.
8. Przedborski, S., Jackson-Lewis, V., Kostic, V., Carlson, E., Epstein, C. J. & Cadet, J. L. (1992) J. Neurochem. 58, 1760-1767.
9. Przedborski, S., Kostic, V., Jackson-Lewis, V., Naini, A. B., Simonetti, S., Fahn, S., Carlson, E., Epstein, C. J. & Cadet, J. L. (1992) J. Neurosci. 12, 1658-1667.
10. Halliwell, B. & Gutteridge, J. M. (1991) Free Radicals in Biology and Medicine (Clarendon, Oxford).
11. Hasegawa, E., Takeshige, K., Oishi, T., Murai, Y. & Minakami, S. (1990) Biochem. Biophys. Res. Commun. 170, 1049-1055.
12. Beckman, J. S., Beckman, T. W., Chen, J., Marshall, P. A. & Freeman, B. A. (1990) Proc. Natl. Acad. Sci. USA 87, 1620-1624.
13. Schulz, J. B., Matthews, R. T., Muqit, M. M. K., Browne, S. E. & Beal, M. F. (1995) J. Neurochem. 64, 936-939.
14. Moore, P. K., Wallace, P., Gaffen, Z., Hart, S. L. & Babbedge, R. C. (1993) Br. J. Pharmacol. 110, 219-224.
15. Reches, A., Wagner, H. R., Jiang, D., Jackson, V. & Fahn, S. (1982) Life Sci. 31, 37-44.
16. Huang, P. L., Dawson, T. M., Bredt, D. S., Snyder, S. H. & Fishman, M. C. (1993) Cell 75, 1273-1285.
17. Lowry, O. H., Rosenbrough, N. J., Farr, A. L. & Randall, R. J. (1951) J. Biol. Chem. 193, 265-275.
18. Przedborski, S., Levivier, M., Raftopoulos, C., Naini, A. B. & Hildebrand, J. (1995) Mov. Disord. 10, 28-36.
19. Gallyas, F., Wolff, J. R., Bottcher, H. & Zaborszky, L. (1980) Stain Technol. 55, 299-306.
20. Muthane, U., Ramsay, K. A., Jiang, H., Jackson-Lewis, V., Donaldson, D., Fernando, S., Ferreira, M. & Przedborski, S. (1994) Exp. Neurol. 126, 195-204.
21. Sidman, R. L., Angevine, J. B., Jr., & Pierce, E. T. (1971) Atlas of the Mouse Brain and Spinal Cord (Harvard Univ. Press, Cambridge, MA).
22. Abercrombie, M. (1946) Anat. Rec. 94, 239-247.
23. Hallman, H., Lange, J., Olson, L., Stromberg, I. & Jonsson, G. (1985) J. Neurochem. 44, 117-127.
24. Heikkila, R. E., Hess, A. & Duvoisin, R. C. (1984) Science 224, 1451-1453.
25. Ricaurte, G. A. & McCann, U. D. (1992) Ann. N.Y. Acad. Sci. 648, 371-382.
26. Hallman, H., Olson, L. & Jonsson, G. (1984) Eur. J. Pharmacol. 97, 133-136.
27. Markey, S. P., Johannessen, J. N., Chiueh, C. C., Burns, R. S. & Herkenham, M. A. (1984) Nature (London) 311, 464-467.
28. Heikkila, R. E., Manzino, L., Cabbat, F. S. & Duvoisin, R. C. (1984) Nature (London) 311, 467-469.
29. Javitch, J. A., D'Amato, R. J., Strittmatter, S. M. & Snyder, S. H. (1985) Proc. Natl. Acad. Sci. USA 82, 2173-2177.
30. Ramsey, R. R. & Singer, T. (1986) J. Biol. Chem. 261, 7585-7587.
31. Nicklas, W. J., Yougster, S. K., Kindt, M. V. & Heikkila, R. E. (1987) Life Sci. 40, 721-729.
32. Vays, I., Heikkila, R. E. & Nicklas, W. J. (1986) J. Neurochem. 46, 1501-1507.
33. Giovanni, A., Sieber, B. A., Heikkila, R. E. & Sonsalla, P. K. (1991) J. Pharmacol. Exp. Ther. 257, 691-697.
34. Kelly, P. A. T., Ritchie, I. M. & Arbuthnott, G. W. (1995) J. Cerebr. Blood Flow Metab. 15, 766-773.
35. Bland-Ward, P. A. & Moore, P. K. (1995) Life Sci. 57, PL131-PL135.
36. Medhurst, A. D., Greenlees, C., Parsons, A. A. & Smith, S. J. (1994) Arch. Biochem. Biophys. 314, 360-366.
37. Wolff, D. J. & Gribin, B. J. (1994) Arch. Biochem. Biophys. 311, 300-306.
38. Smith, T. S., Swerdlow, R. H., Parker, W. D., Jr., & Bennett, J. P., Jr. (1994) NeuroReport 5, 2598-2600.
39. Rees, D. D., Palmer, R. M. J., Schulz, R., Hodson, H. F. & Moncada, S. (1990) Br. J. Pharmacol. 101, 746-752.
40. O'Dell, T. J., Huang, P. L., Dawson, T. M., Dinerman, J. L., Snyder, S. H., Kandel, E. R. & Fishman, M. C. (1994) Science 265, 542-546.
41. Francis, J. W., Von Visger, J., Markelonis, G. J. & Oh, T. H. (1995) Neurotoxicol. Teratol. 17, 7-12.
42. Viswanathan, M., de Oliveira, A. M., Wu, R. M., Chiueh, C. C. & Saavedra, J. M. (1994) Cell. Mol. Neurobiol. 14, 99-104.
43. Fuller, R. W., Hahn, R. A., Snoddy, H. D. & Wikel, J. H. (1984) Biochem. Pharmacol. 19, 2957-2960.
44. Dun, N. J., Dun, S. L., Wu, S. Y., Förstermann, U., Schmidt, H. H. H. W. & Tseng, L. F. (1993) Neuroscience 54, 845-857.
45. Dun, N. J., Dun, S. L. & Forstermann, U. (1994) Neuroscience 59, 429-445.
46. Bredt, D. S., Glatt, C. E., Huang, P. L., Fotuhi, M., Dawson, T. M. & Snyder, S. H. (1991) Neuron 7, 615-624.
47. Dawson, T. M. & Snyder, S. H. (1994) J. Neurosci. 14, 5147-5159.
48. Herkenham, M., Little, M. D., Bankiewicz, K., Yang, S. C., Markey, S. P. & Johannessen, J. N. (1991) Neuroscience 40, 133-158.
49. Przedborski, S., Levivier, M., Jiang, H., Ferreira, M., Jackson-Lewis, V., Donaldson, D. & Togasaki, D. M. (1995) Neuroscience 67, 631-647.
50. Dawson, V. L., Kizushi, V. M., Huang, P. L., Snyder, S. H. & Dawson, T. M. (1996) J. Neurosci., in press.
51. Beckman, J. S. (1991) J. Dev. Physiol. 15, 53-59.
52. Beckman, J. S. (1994) Ann. N.Y. Acad. Sci. 738, 69-75.
53. Walker, M. J., Jenner, P. & Marsden, C. D. (1991) Biochem. Pharmacol. 42, 913-919.
54. Beckman, J. S., Chen, J., Crow, J. P. & Ye, Y. Z. (1994) Prog. Brain Res. 103, 371-380.
55. Beckman, J. S., Ischiropoulos, H., Zhu, L., Woerd, M., Smith, C., Chen, J., Harrison, J., Martin, J. C. & Tsai, M. (1992) Arch. Biochem. Biophys. 298, 438-445.
56. Zhang, J., Dawson, V. L. & Dawson, T. M. (1994) Science 263, 687-689.
57. Berger, N. A. (1985) Radiat. Res. 101, 4-15.