Participation of transmembrane domain 1 of presenilin 1 in the catalytic pore structure of the γ-secretase

Journal of Neuroscience

Volumn 30, Issue 47, 2010, Pages 15943-15950

  Takagi, Shizuka ^a   Tominaga, Aya ^a   Sato, Chihiro ^a,b   Tomita, Taisuke ^a   Iwatsubo, Takeshi ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; PRESENILIN 1;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HYDROPHOBICITY; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF;

AMINO ACID SEQUENCE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CATALYTIC DOMAIN; CELL LINE; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; PRESENILIN-1; PROTEIN STRUCTURE, TERTIARY;

EID: 78649393418     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3318-10.2010     Document Type: Article

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