Retrovirus-mediated gene transfer and expression cloning: Powerful tools in functional genomics

Experimental Hematology

Volumn 31, Issue 11, 2003, Pages 1007-1014

  Kitamura, Toshio ^a   Koshino, Yuko ^a   Shibata, Fumi ^a   Oki, Toshihiko ^a   Nakajima, Hideaki ^a   Nosaka, Tetsuya ^b   Kumagai, Hidetoshi ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE RECEPTOR; GAG PROTEIN; HYBRID PROTEIN; RETROVIRUS VECTOR; SIGNAL PEPTIDE; STAT5 PROTEIN;

DNA ISOLATION; DNA PACKAGING; FLUORESCENCE LOCALIZATION RETROVIRUS MEDIATED EXPRESSION SCREENING; GENE EXPRESSION; GENE FUNCTION; GENE SEQUENCE; GENE STRUCTURE; GENE TRANSFER; GENOMICS; MOLECULAR CLONING; MUTAGENESIS; NONHUMAN; OPEN READING FRAME; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RETROVIRUS; REVIEW; SIGNAL SEQUENCE TRAP;

UNIDENTIFIED RETROVIRUS;

EID: 0142227052     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(03)00260-1     Document Type: Review

References (42)

1. Berg P., Baltimore D., Brenner S., Roblin R.O. jr.3rd, Singer M.F. Asilomar conference on recombinant DNA molecules. Science. 188:1975;991-994.
2. Efstratiadis A., Kafatos F.C., Maniatis T. The primary structure of rabbit beta-globin mRNA as determined from cloned DNA. Cell. 10:1977;571-585.
3. Gluzman Y. SV40-transformed simian cells support the replication of early SV40 mutants. Cell. 23:1981;175-182.
4. Okayama H., Berg P. A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells. Mol Cell Biol. 3:1983;280-289.
5. Rayner J.R., Gonda T.J. A simple and efficient procedure for generating stable expression libraries by cDNA cloning in a retroviral vector. Mol Cell Biol. 14:1994;880-887.
6. Wong B.Y., Chen H., Chung S.W., Wong P.M. High-efficiency identification of genes by functional analysis from a retroviral cDNA expression library. J Virol. 68:1994;5523-5531.
7. Whitehead I., Kirk H., Kay R. Expression cloning of oncogenes by retroviral transfer of cDNA libraries. Mol Cell Biol. 15:1995;704-710.
8. Kitamura T., Onishi M., Kinoshita S., Shibuya A., Miyajima A., Nolan G.P. Efficient screening of retroviral cDNA expression libraries. Proc Natl Acad Sci USA. 92:1995;9146-9150.
9. Onishi M., Kinoshita S., Morikawa Y., et al. Applications of retrovirus-mediated expression cloning. Exp Hematol. 24:1996;324-327.
10. Pear W.S., Nolan G.P., Scott M.L., Baltimore D. Production of high-titer helper-free retroviruses by transient transfection. Proc Natl Acad Sci USA. 90:1993;8392-8396.
11. Morita S., Kojima T., Kitamura T. Plat-E: an efficient and stable system for transient packaging of retroviruses. Gene Ther. 7:2000;1063-1066.
12. Feng Y., Broder C.C., Kennedy P.E., Berger E.A. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science. 272:1996;872-877.
13. Deng H.K., Unutmaz H.K., Kewal Ramani V.N., Littman D.R. Expression cloning of new receptors used by simian and human immunodeficiency viruses. Nature. 388:1997;296-300.
14. Yang Y.L., Guo L., Xu S., et al. Receptors for polytropic and xenotropic mouse leukaemia viruses encoded by a single gene at Rmc1. Nat Genet. 21:1999;216-219.
15. Sasazuki T., Sawada T., Sakon S., et al. Identification of a novel transcriptional activator, BSAC, by a functional cloning to inhibit tumor necrosis factor-induced cell death. J Biol Chem. 277:2002;28853-28860.
16. Perez O.D., Kinoshita S., Hitoshi Y., et al. Activation of the PKB/AKT pathway by ICAM-2. Immunity. 16:2002;51-65.
17. Starr R., Wilson T.A., Viney E.M., et al. A family of cytokine-inducible inhibitors of signaling. Nature. 387:1997;917-921.
18. Kawashima T., Murata K., Akira S., et al. STAT5 induces macrophage differentiation of M1 leukemia cells through activation of IL-6 production mediated by NF-kappaB p65. J Immunol. 167:2001;3652-3660.
19. Hirose K., Kawashima T., Iwamoto I., Nosaka T., Kitamura T. MgcRacGAP is involved in cytokinesis through associating with mitotic spindle and midbody. J Biol Chem. 276:2001;5821-5828.
20. Minoshima Y., Kawashima T., Hirose K., et al. Phosphorylation by Aurora B converts MgcRacGAP to a RhoGAP during cytokinesis. Dev Cell. 4:2003;549-560.
21. Onishi M., Mui A.L.F., Morikawa Y., et al. Identification of an oncogenic form of the thrombopoietin receptor MPL using retrovirus-mediated gene transfer. Blood. 88:1996;1399-1406.
22. Onishi M., Nosaka T., Misawa K., et al. Identification and characterization of a constitutive active STAT5 mutant that promotes cell proliferation. Mol Cell Biol. 18:1998;3871-3879.
23. Tashiro K., Tada H., Heilker R., Shirozu M., Nakano T., Honjo T. Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins. Science. 261:1993;600-603.
24. Klein R.D., Gu Q., Goddard A., Rothental A. Selection for genes encoding secreted proteins and receptors. Proc Natl Acad Sci USA. 93:1996;7108-7113.
25. Kojima T., Kitamura T. A novel signal sequence trap method using retrovirus-mediated gene transfer. Nat Biotechnol. 17:1999;487-490.
26. Misawa K., Nosaka T., Morita S., et al. A method to identify cDNAs based on localization of green fluorescent protein fusion products. Proc Natl Acad Sci USA. 97:2000;3062-3066.
27. Yamaoka S., Courtois G., Bessia C., et al. Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation. Cell. 93:1998;1231-1240.
28. Stoecklin G., Colombi M., Raineri I., et al. Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover. EMBO J. 21:2002;4709-4718.
29. Tulin E.E., Onoda N., Maeda M., et al. A novel secreted form of immune suppressor factor with high homology to vacuolar ATPases identified by forward genetic approach of functional screening based on cell proliferation. J Biol Chem. 276:2001;27519-27526.
30. Miller D.A. Retrovirus packaging cells. Hum Gene Ther. 1:1990;5-14.
31. Stocking C., Grez M., Ostertag W. Regulation of retrovirus infection and expression in embryonic and hematopoietic stem cells. Doerfler W., Bohm P. Virus Strategies: Molecular Biology and Pathogenesis. 1993;433-455 VCH Verlagsgesellschaft, Weinheim.
32. Kelly P.F., Vandergriff J., Nathwani A., Nienhuis A.W., Vanin E.F. Highly efficient gene transfer into cord blood nonobese diabetic/severe combined immunodeficiency repopulating cells by oncoretroviral vector particles pseudotyped with the feline endogenous retrovirus (RD114) envelope protein. Blood. 96:2000;1206-1214.
33. Riviere I., Brose K., Mulligan R.C. Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells. Proc Natl Acad Sci USA. 92:1995;6733-6737.
34. Fujio K., Misaki Y., Setoguchi K., et al. Functional reconstitution of class II MHC-restricted T cell immunity mediated by retroviral transfer of the alpha beta TCR complex. J Immunol. 165:2000;528-532.
35. Kawakami Y., Miura T., Bissonnette R., et al. Bruton's tyrosine kinase regulates apoptosis and JNK/SAPK kinase activity. Proc Natl Acad Sci USA. 94:1997;3938-3942.
36. Baum C., Hegewisch-Becker S., Eckert H.G., Stocking C., Ostertag W. Novel retroviral vectors for efficient expression of the multidrug resistance (mdr-1) gene in early hematopoietic cells. J Virol. 69:1995;7541-7547.
37. Hawley R.G., Lieu F.H.L., Fong A.Z.C., Hawley T.S. Versatile retroviral vectors for potential use in gene therapy. Gene Ther. 1:1994;136-138.
38. Xu X., Leo C., Jang Y., et al. Dominant effector genetics in mammalian cells. Nat Genet. 27:2001;23-29.
39. Sablitzky F., Jonsson J.-I., Cohen B.L., Phillips R.A. High frequency expression of integrated provirus derived from enhancer trap retroviruses. Cell Growth Differ. 4:1993;451-459.
40. Ishida Y., Leder P. RET: a poly A-trap retrovirus vector for reversible disruption and expression monitoring of genes in living cells. Nucl Acids Res. 27:1995;e35.
41. Lund A.H., Turner G., Trubetskoy A., et al. Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice. Nat Genet. 32:2002;160-165.
42. Suzuki T., Shen H., Akagi K., et al. New genes involved in cancer identified by retroviral tagging. Nat Genet. 32:2002;166-174.