Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain

Development

Volumn 131, Issue 15, 2004, Pages 3805-3819

  Ferri, Anna L M ^a   Cavallaro, Maurizio ^a   Braida, Daniela ^b   Di Cristofano, Antonello ^c   Canta, Annalisa ^a   Vezzani, Annamaria ^d   Ottolenghi, Sergio ^a   Pandolfi, Pier Paolo ^c   Sala, Mariaelvina ^b   DeBiasi, Silvia ^b   Nicolis, Silvia K ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

Hippocampal precursors; Mouse; Nervous system; Neural stem cells; Neurodegeneration; Neurogenesis; Neuronal inclusions; Sox2; Transcription factors

Indexed keywords

CYTOPLASM PROTEIN; LEVODOPA; LIPID; NESTIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DISEASE; BRAIN MALFORMATION; BRAIN VENTRICLE DILATATION; CELL LOSS; CELL PROLIFERATION; CELL SPECIFICITY; CIRCLING BEHAVIOR; CONTROLLED STUDY; CORPUS STRIATUM; EMBRYO; EMBRYO CELL; ENHANCER REGION; EPENDYMA CELL; EPILEPSY; FEMALE; GENE DELETION; HETEROZYGOTE; HIPPOCAMPUS; MOUSE; MOUSE MUTANT; NERVE CELL DIFFERENTIATION; NERVE DEGENERATION; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEPTUM PELLUCIDUM; STEM CELL; THALAMUS;

ALLELES; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; CELL SURVIVAL; CULTURE TECHNIQUES; DNA-BINDING PROTEINS; ELECTROENCEPHALOGRAPHY; EMBRYO; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HMGB PROTEINS; HUMANS; IN SITU HYBRIDIZATION; MICE; MICE, TRANSGENIC; MUTATION; NEURODEGENERATIVE DISEASES; NEURONS; NUCLEAR PROTEINS; TRANSCRIPTION FACTORS;

ANIMALIA; MAMMALIA;

EID: 4444378766     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01204     Document Type: Article

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