-
1
-
-
73149118890
-
Signaling in malignant astrocytomas: Role of neural stem cells and its therapeutic implications
-
Alcantara Llaguno SR, Chen J, Parada LF. Signaling in malignant astrocytomas: role of neural stem cells and its therapeutic implications. Clin Cancer Res 200915:7124-7129
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7124-7129
-
-
Alcantara Llaguno, S.R.1
Chen, J.2
Parada, L.F.3
-
2
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons DW, Jones S, Zhang X, et al. An integrated genomic analysis of human glioblastoma multiforme. Science 2008321: 1807-1812
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
-
3
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007128: 683-692
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
4
-
-
63449086968
-
Epigenetic mechanisms in glioblastoma multiforme
-
Nagarajan RP, Costello JF. Epigenetic mechanisms in glioblastoma multiforme. Semin Cancer Biol 200919:188-197
-
(2009)
Semin Cancer Biol
, vol.19
, pp. 188-197
-
-
Nagarajan, R.P.1
Costello, J.F.2
-
5
-
-
0343621494
-
Aberrant CpG-island methylation has non-random and tumour-type-specific patterns
-
Costello JF, Fruhwald MC, Smiraglia DJ, et al. Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet 200024:132-138
-
(2000)
Nat Genet
, vol.24
, pp. 132-138
-
-
Costello, J.F.1
Fruhwald, M.C.2
Smiraglia, D.J.3
-
6
-
-
0037531563
-
Distinct methylation profiles of glioma subtypes
-
DOI 10.1002/ijc.11175
-
6. Uhlmann K, Rohde K, Zeller C, et al. Distinct methylation profiles of glioma subtypes. Int J Cancer 2003;106:52-59 (Pubitemid 36750387)
-
(2003)
International Journal of Cancer
, vol.106
, Issue.1
, pp. 52-59
-
-
Uhlmann, K.1
Rohde, K.2
Zeller, C.3
Szymas, J.4
Vogel, S.5
Marczinek, K.6
Thiel, G.7
Nurnberg, P.8
Laird, P.W.9
-
7
-
-
13144290928
-
Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma
-
DOI 10.1186/1471-2407-4-65
-
7. Yu J, Zhang H, Gu J, et al. Methylation profiles of thirty four promoterCpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma. BMC Cancer 2004;4:65. (Pubitemid 40180289)
-
(2004)
BMC Cancer
, vol.4
, pp. 65
-
-
Yu, J.1
Zhang, H.2
Gu, J.3
Lin, S.4
Li, J.5
Lu, W.6
Wang, Y.7
Zhu, J.8
-
8
-
-
33749039999
-
Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation
-
DOI 10.1158/0008-5472.CAN-06-1547
-
8. Cadieux B, Ching TT, VandenBerg SR, Costello JF. Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation. Cancer Res 2006;66:8469-8476 (Pubitemid 44449159)
-
(2006)
Cancer Research
, vol.66
, Issue.17
, pp. 8469-8476
-
-
Cadieux, B.1
Ching, T.-T.2
Vandenberg, S.R.3
Costello, J.F.4
-
9
-
-
33746163546
-
Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma
-
DOI 10.1158/0008-5472.CAN-05-4453
-
9. Foltz G, Ryu GY, Yoon JG, et al. Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma. Cancer Res 2006;66:6665-6674 (Pubitemid 44085623)
-
(2006)
Cancer Research
, vol.66
, Issue.13
, pp. 6665-6674
-
-
Foltz, G.1
Ryu, G.-Y.2
Yoon, J.-G.3
Nelson, T.4
Fahey, J.5
Frakes, A.6
Lee, H.7
Field, L.8
Zander, K.9
Sibenaller, Z.10
Ryken, T.C.11
Vibhakar, R.12
Hood, L.13
Madan, A.14
-
10
-
-
33747889966
-
Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma
-
DOI 10.1158/0008-5472.CAN-05-4552
-
10. Kim TY, Zhong S, Fields CR, Kim JH, Robertson KD. Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. Cancer Res 2006;66:7490-7501 (Pubitemid 44289203)
-
(2006)
Cancer Research
, vol.66
, Issue.15
, pp. 7490-7501
-
-
Kim, T.-Y.1
Zhong, S.2
Fields, C.R.3
Kim, J.H.4
Robertson, K.D.5
-
11
-
-
38049148239
-
Loss of pericentromeric DNA methylation pattern in human glioblastoma is associated with altered DNA methyltransferases expression and involves the stem cell compartment
-
Fanelli M, Caprodossi S, Ricci-Vitiani L, et al. Loss of pericentromeric DNA methylation pattern in human glioblastoma is associated with altered DNA methyltransferases expression and involves the stem cell compartment. Oncogene 200827:358-365
-
(2008)
Oncogene
, vol.27
, pp. 358-365
-
-
Fanelli, M.1
Caprodossi, S.2
Ricci-Vitiani, L.3
-
12
-
-
33748055105
-
MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-containing genes in lung cancer cells
-
DOI 10.1158/0008-5472.CAN-06-1888
-
12. Rauch T, Li H, Wu X, Pfeifer GP. MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-containing genes in lung cancer cells. Cancer Res 2006;66:7939-7947 (Pubitemid 44299157)
-
(2006)
Cancer Research
, vol.66
, Issue.16
, pp. 7939-7947
-
-
Rauch, T.1
Li, H.2
Wu, X.3
Pfeifer, G.P.4
-
13
-
-
33846569960
-
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
-
Ohm JE, McGarvey KM, Yu X, et al. A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet 200739:237-412.
-
(2007)
Nat Genet
, vol.39
, pp. 237-412
-
-
Ohm, J.E.1
McGarvey, K.M.2
Yu, X.3
-
14
-
-
34248361968
-
Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarraybased methylated CpG island recovery assay
-
Rauch T, Wang Z, Zhang X, et al. Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarraybased methylated CpG island recovery assay. Proc Natl Acad Sci U S A2007104:5527-5532
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 5527-5532
-
-
Rauch, T.1
Wang, Z.2
Zhang, X.3
-
15
-
-
33846649587
-
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
-
Schlesinger Y, Straussman R, Keshet I, et al. Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nat Genet 200739:232-236
-
(2007)
Nat Genet
, vol.39
, pp. 232-236
-
-
Schlesinger, Y.1
Straussman, R.2
Keshet, I.3
-
16
-
-
33846576622
-
Epigenetic stem cell signature in cancer
-
DOI 10.1038/ng1941, PII NG1941
-
16. Widschwendter M, Fiegl H, EgIe D, et al. Epigenetic stem cell signature in cancer. Nat Genet 2007;39:157-158 (Pubitemid 46184343)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 157-158
-
-
Widschwendter, M.1
Fiegl, H.2
Egle, D.3
Mueller-Holzner, E.4
Spizzo, G.5
Marth, C.6
Weisenberger, D.J.7
Campan, M.8
Young, J.9
Jacobs, I.10
Laird, P.W.11
-
17
-
-
51349105905
-
Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line
-
Gal-Yam EN, Egger G, Iniguez L, et al. Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line. Proc Natl Acad Sci U S A 2008105: 12979-12984
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 12979-12984
-
-
Gal-Yam, E.N.1
Egger, G.2
Iniguez, L.3
-
18
-
-
63449136848
-
DNA methylation patterns in lung carcinomas
-
Pfeifer GP, Rauch TA. DNA methylation patterns in lung carcinomas. Semin Cancer Biol 200919:181-187
-
(2009)
Semin Cancer Biol
, vol.19
, pp. 181-187
-
-
Pfeifer, G.P.1
Rauch, T.A.2
-
19
-
-
61449322942
-
The Ml RA method for DNA methylation analysis
-
Rauch TA, Pfeifer GP. The Ml RA method for DNA methylation analysis. Methods Mol Biol 2009507:65-75.
-
(2009)
Methods Mol Biol
, vol.507
, pp. 65-75
-
-
Rauch, T.A.1
Pfeifer, G.P.2
-
20
-
-
58849091905
-
A human B cell methylome at 100-base pair resolution
-
Rauch TA, Wu X, Zhong X, Riggs AD, Reifer GP. A human B cell methylome at 100-base pair resolution. Proc Natl Acad Sei U S A 2009106:671-678
-
(2009)
Proc Natl Acad Sei U S A
, vol.106
, pp. 671-678
-
-
Rauch, T.A.1
Wu, X.2
Zhong, X.3
Riggs, A.D.4
Reifer, G.P.5
-
21
-
-
0030825309
-
COBRA: A sensitive and quantitative DNA methylation assay
-
DOI 10.1093/nar/25.12.2532
-
21. Xiong Z, Laird PW. COBRA: a sensitive and quantitative DNA methylation assay. Nucleic Acids Res 1997;25:2532-2534 (Pubitemid 27303718)
-
(1997)
Nucleic Acids Research
, vol.25
, Issue.12
, pp. 2532-2534
-
-
Xiong, Z.1
Laird, P.W.2
-
22
-
-
64349091471
-
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells
-
Ball MP, Li JB, Gao Y, et al. Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells. Nat Biotechnol 200927:361-368
-
(2009)
Nat Biotechnol
, vol.27
, pp. 361-368
-
-
Ball, M.P.1
Li, J.B.2
Gao, Y.3
-
23
-
-
38349135680
-
High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer
-
Rauch TA, Zhong X, Wu X, et al. High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer. Proc Natl Acad Sci U S A 2008105:252-257
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 252-257
-
-
Rauch, T.A.1
Zhong, X.2
Wu, X.3
-
24
-
-
33646865180
-
Control of developmental regulators by Polycomb in human embryonic stem cells
-
Lee Tl, Jenner RG, Boyer LA, et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 2006; 125:301-313
-
(2006)
Cell
, vol.125
, pp. 301-313
-
-
Tl, L.1
Jenner, R.G.2
Boyer, L.A.3
-
25
-
-
26444529054
-
A novel gene family NBPF: Intricate structure generated by gene duplications during primate evolution
-
DOI 10.1093/molbev/msi222
-
25. Vandepoele K, Van Roy N, Staes K, Speleman F, van Roy F. A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution. Mol Biol Evol 2005;22:2265-2274 (Pubitemid 41437807)
-
(2005)
Molecular Biology and Evolution
, vol.22
, Issue.11
, pp. 2265-2274
-
-
Vandepoele, K.1
Van Roy, N.2
Staes, K.3
Speleman, F.4
Van Roy, F.5
-
26
-
-
0036429193
-
The human and mouse replication-dependent histone genes
-
DOI 10.1016/S0888-7543(02)96850-3
-
26. Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ. The human and mouse replication-dependent histone genes. Genomics 2002;80: 487-498 (Pubitemid 35333791)
-
(2002)
Genomics
, vol.80
, Issue.5
, pp. 487-498
-
-
Marzluff, W.F.1
Gongidi, P.2
Woods, K.R.3
Jin, J.4
Maltais, L.J.5
-
27
-
-
33751505540
-
DNA methylation profiling of human chromosomes 6, 20 and 22
-
Eckhardt F, Lewin J, Cortese R, et al. DNA methylation profiling of human chromosomes 6, 20 and 22. Nat Genet 2006;38: 1378-1385
-
(2006)
Nat Genet
, vol.38
, pp. 1378-1385
-
-
Eckhardt, F.1
Lewin, J.2
Cortese, R.3
-
28
-
-
35948981875
-
Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters
-
DOI 10.1371/journal.pgen.0030181
-
28. Shen L, Kondo Y, Guo Y, et al. Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters. PLoS Genet 2007;3:2023-2036 (Pubitemid 350072065)
-
(2007)
PLoS Genetics
, vol.3
, Issue.10
, pp. 2023-2026
-
-
Shen, L.1
Kondo, Y.2
Guo, Y.3
Zhang, J.4
Zhang, L.5
Ahmed, S.6
Shu, J.7
Chen, X.8
Waterland, R.A.9
Issa, J.-P.J.10
-
29
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
DOI 10.1038/ng1990, PII NG1990
-
29. Weber M, Hellmann I, Stadler MB, et al. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 2007;39:457-466 (Pubitemid 46514772)
-
(2007)
Nature Genetics
, vol.39
, Issue.4
, pp. 457-466
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
Ramos, L.4
Paabo, S.5
Rebhan, M.6
Schubeler, D.7
-
30
-
-
38949212693
-
A novel CpG island set identifies tissue-specific methylation at developmental gene loci
-
Illingworth R, Kerr A, Desousa D, et al. A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol 20086:e22.
-
(2008)
PLoS Biol
, vol.6
-
-
Illingworth, R.1
Kerr, A.2
Desousa, D.3
-
31
-
-
32644467225
-
Methylated tumor-specific DNA as a plasma biomarker in patients with glioma
-
Weaver KD, Grossman SA, Herman JG. Methylated tumor-specific DNA as a plasma biomarker in patients with glioma. Cancer Invest 200624:35-40.
-
(2006)
Cancer Invest
, vol.24
, pp. 35-40
-
-
Weaver, K.D.1
Grossman, S.A.2
Herman, J.G.3
-
32
-
-
77950692374
-
DNA methylation of polycomb group target genes in cores taken from breast cancer centre and periphery
-
In press
-
Fourkala EO, Hauser-Kronberger C, Apostolidou S, et al. DNA methylation of polycomb group target genes in cores taken from breast cancer centre and periphery. Breast Cancer Res Treat. In press 2010.
-
(2010)
Breast Cancer Res Treat.
-
-
Fourkala, E.O.1
Hauser-Kronberger, C.2
Apostolidou, S.3
-
33
-
-
67549095233
-
Methylation of homeobox genes is a frequent and early epigenetic event in breast cancer
-
Tommasi S, Karm DL, Wu X, Yen Y, Pfeifer GP. Methylation of homeobox genes is a frequent and early epigenetic event in breast cancer. Breast Cancer Res 200911:R14.
-
(2009)
Breast Cancer Res
, vol.11
-
-
Tommasi, S.1
Karm, D.L.2
Wu, X.3
Yen, Y.4
Pfeifer, G.P.5
-
34
-
-
66449121883
-
Histone H3 lysine 27 trimethylation in adult differentiated colon associated to cancer DNA hypermethylation
-
Rada-lglesias A, Enroth S, Andersson R, et al. Histone H3 lysine 27 trimethylation in adult differentiated colon associated to cancer DNA hypermethylation. Epigenetics 20094:107-113
-
(2009)
Epigenetics
, vol.4
, pp. 107-113
-
-
Rada-lglesias, A.1
Enroth, S.2
Andersson, R.3
-
35
-
-
68549099896
-
DNA hypermethylation accompanied by transcriptional repression in follicular lymphoma
-
Bennett LB, Schnabel JL, Kelchen JM, et al. DNA hypermethylation accompanied by transcriptional repression in follicular lymphoma. Genes Chromosomes Cancer 200948:828-841
-
(2009)
Genes Chromosomes Cancer
, vol.48
, pp. 828-841
-
-
Bennett, L.B.1
Schnabel, J.L.2
Kelchen, J.M.3
-
36
-
-
69949087520
-
A microarray-based DNA methylation study of glioblastoma multiforme
-
Martinez R, Martin-Subero Jl, Rohde V, et al. A microarray-based DNA methylation study of glioblastoma multiforme. Epigenetics 20094:255-264
-
(2009)
Epigenetics
, vol.4
, pp. 255-264
-
-
Martinez, R.1
Jl, M.-S.2
Rohde, V.3
-
37
-
-
57849109837
-
Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model
-
Alcantara Llaguno S, Chen J, Kwon CH, et al. Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell 200915:45-56.
-
(2009)
Cancer Cell
, vol.15
, pp. 45-56
-
-
Alcantara Llaguno, S.1
Chen, J.2
Kwon, C.H.3
-
38
-
-
65649142176
-
Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model
-
Wang Y, Yang J, Zheng H, et al. Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model. Cancer Cell 2009; 15:514-526
-
(2009)
Cancer Cell
, vol.15
, pp. 514-526
-
-
Wang, Y.1
Yang, J.2
Zheng, H.3
-
39
-
-
33845610993
-
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
-
DOI 10.1038/nature05349, PII NATURE05349
-
39. Piccirillo SG, Reynolds BA, Zanetti N, et al. Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumourinitiating cells. Nature 2006;444:761-765 (Pubitemid 44949605)
-
(2006)
Nature
, vol.444
, Issue.7120
, pp. 761-765
-
-
Piccirillo, S.G.M.1
Reynolds, B.A.2
Zanetti, N.3
Lamorte, G.4
Binda, E.5
Broggi, G.6
Brem, H.7
Olivi, A.8
Dimeco, F.9
Vescovi, A.L.10
|