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Volumn 5, Issue 9, 2010, Pages 1329-1347

Type B coxsackieviruses and their interactions with the innate and adaptive immune systems

Author keywords

adaptive immunity; autophagy; coxsackievirus; innate immunity; loop pathogenesis; mitochondria; picornavirus; RIG I like recepto; T cell; Toll like receptor

Indexed keywords

PROTEIN KINASE R; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; VIRUS RNA;

EID: 77957593459     PISSN: 17460913     EISSN: None     Source Type: Journal    
DOI: 10.2217/fmb.10.101     Document Type: Review
Times cited : (49)

References (209)
  • 2
    • 0036026868 scopus 로고    scopus 로고
    • Immunopathology during coxsackievirus infection
    • Whitton JL: Immunopathology during coxsackievirus infection. Springer Semin. Immunopathol. 24, 201-213 (2002)
    • (2002) Springer Semin. Immunopathol , vol.24 , pp. 201-213
    • Whitton, J.L.1
  • 3
    • 43649084269 scopus 로고    scopus 로고
    • Pediatric group b coxsackievirus infections
    • Romero JR: Pediatric group B coxsackievirus infections. Curr. Top. Microbiol. Immunol. 323, 223-239 (2008).
    • (2008) Curr. Top Microbiol Immunol , vol.323 , pp. 223-239
    • Romero, J.R.1
  • 4
    • 0023266582 scopus 로고
    • The role of myocarditis in end stage dilated cardiomyopathy
    • OConnell JB: The role of myocarditis in end-stage dilated cardiomyopathy. Tex. Heart Inst. J. 14, 268-275 (1987).
    • (1987) Tex. Heart Inst. J , vol.14 , pp. 268-275
    • O'Connell, J.B.1
  • 5
    • 0027524996 scopus 로고
    • Viral myocarditis: A paradigm for understanding the pathogenesis and treatment of dilated cardiomyopathy
    • Sole MJ, Liu P: Viral myocarditis: a paradigm for understanding the pathogenesis and treatment of dilated cardiomyopathy. J. Am. Coll. Cardiol. 22, A99-A105 (1993).
    • (1993) J. Am. Coll. Cardiol , vol.22
    • Sole, M.J.1    Liu, P.2
  • 6
    • 33745903422 scopus 로고    scopus 로고
    • Coxsackievirus myocarditis: Interplay between virus and host in the pathogenesis of heart disease
    • Tam PE: Coxsackievirus myocarditis: interplay between virus and host in the pathogenesis of heart disease. Viral Immunol. 19, 133-146 (2006).
    • (2006) Viral Immunol , vol.19 , pp. 133-146
    • Tam, P.E.1
  • 7
    • 0031942786 scopus 로고    scopus 로고
    • A cluster of cases of neonatal coxsackievirus b meningitis and myocarditis
    • Daley AJ, Isaacs D, Dwyer DE, Gilbert GL: A cluster of cases of neonatal coxsackievirus B meningitis and myocarditis. J. Paediatr. Child Health 34, 196-198 (1998).
    • (1998) J. Paediatr. Child Health , vol.34 , pp. 196-198
    • Daley, A.J.1    Isaacs, D.2    Dwyer, D.E.3    Gilbert, G.L.4
  • 8
    • 0034608223 scopus 로고    scopus 로고
    • Coxsackievirus infection of the pancreas: Evaluation of receptor expression pathogenesis and immunopathology
    • Mena I, Fischer C, Gebhard JR, Perry CM, Harkins S, Whitton JL: Coxsackievirus infection of the pancreas: evaluation of receptor expression, pathogenesis, and immunopathology. Virology 271, 276-288 (2000).
    • (2000) Virology , vol.271 , pp. 276-288
    • Mena, I.1    Fischer, C.2    Gebhard, J.R.3    Perry, C.M.4    Harkins, S.5    Whitton, J.L.6
  • 9
    • 4544240699 scopus 로고    scopus 로고
    • Coxsackievirus induced pancreatitis
    • Huber S, Ramsingh AI: Coxsackievirus-induced pancreatitis. Viral Immunol. 17, 358-369 (2004).
    • (2004) Viral Immunol , vol.17 , pp. 358-369
    • Huber, S.1    Ramsingh, A.I.2
  • 10
  • 11
    • 58049193003 scopus 로고    scopus 로고
    • Microbe sensing positive feedback loops and the pathogenesis of inflammatory diseases
    • Beutler B: Microbe sensing, positive feedback loops, and the pathogenesis of inflammatory diseases. Immunol. Rev. 227, 248-263 (2009).
    • (2009) Immunol. Rev. , vol.227 , pp. 248-263
    • Beutler, B.1
  • 12
    • 5944261457 scopus 로고    scopus 로고
    • Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
    • Kurt-Jones EA, Popova L, Kwinn L et al.: Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat. Immunol. 1, 398-401 (2000).
    • (2000) Nat. Immunol , vol.1 , pp. 398-401
    • Kurt Jones, E.A.1    Popova, L.2    Kwinn, L.3
  • 13
    • 34247577195 scopus 로고    scopus 로고
    • Vesicular stomatitis virus glycoprotein g activates a specific antiviral toll like receptor 4 dependent pathway
    • Georgel P, Jiang Z, Kunz S et al.: Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway. Virology 362, 304-313 (2007).
    • (2007) Virology , vol.362 , pp. 304-313
    • Georgel, P.1    Jiang, Z.2    Kunz, S.3
  • 14
    • 4644319638 scopus 로고    scopus 로고
    • Coxsackievirus b4 induced cytokine production in pancreatic cells is mediated through toll like receptor 4
    • Triantafilou K, Triantafilou M: Coxsackievirus B4-induced cytokine production in pancreatic cells is mediated through toll-like receptor 4. J. Virol. 78, 11313-11320 (2004).
    • (2004) J. Virol. , vol.78 , pp. 11313-11320
    • Triantafilou, K.1    Triantafilou, M.2
  • 15
    • 0037406697 scopus 로고    scopus 로고
    • IL 12 receptor b 1 and toll like receptor 4 increase IL 1 b and IL 18 associated myocarditis and coxsackievirus replication
    • Fairweather D, Yusung S, Frisancho S et al.: IL-12 receptor b 1 and Toll-like receptor 4 increase IL-1 b-and IL-18-associated myocarditis and coxsackievirus replication. J. Immunol. 170, 4731-4737 (2003).
    • (2003) J. Immunol. , vol.170 , pp. 4731-4737
    • Fairweather, D.1    Yusung, S.2    Frisancho, S.3
  • 16
    • 34249811203 scopus 로고    scopus 로고
    • Cutting edge: Cross regulation by TLR4 and t cell Ig mucin 3 determines sex differences in inflammatory heart disease
    • Frisancho-Kiss S, Davis SE, Nyland JF et al.: Cutting edge: cross-regulation by TLR4 and T cell Ig mucin-3 determines sex differences in inflammatory heart disease. J. Immunol. 178, 6710-6714 (2007).
    • (2007) J. Immunol. , vol.178 , pp. 6710-6714
    • Frisancho Kiss, S.1    Davis, S.E.2    Nyland, J.F.3
  • 18
    • 33750952070 scopus 로고    scopus 로고
    • Toll like receptor 4 induced cytokine production circumvents protection conferred by TGF b in coxsackievirus-mediated autoimmune myocarditis
    • Richer MJ, Fang D, Shanina I, Horwitz MS: Toll-like receptor 4-induced cytokine production circumvents protection conferred by TGF-b in coxsackievirus-mediated autoimmune myocarditis. Clin. Immunol. 121(3), 339-349 (2006).
    • (2006) Clin. Immunol. , vol.121 , Issue.3 , pp. 339-349
    • Richer, M.J.1    Fang, D.2    Shanina, I.3    Horwitz, M.S.4
  • 19
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double stranded RNA and activation of NF kB by Toll like receptor 3
    • Alexopoulou L, Holt AC, Medzhitov R, Flavell RA: Recognition of double-stranded RNA and activation of NF-kB by Toll-like receptor 3. Nature 413, 732-738 (2001).
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 20
    • 58149510024 scopus 로고    scopus 로고
    • A critical link between toll like receptor 3 and type II interferon signaling pathways in antiviral innate immunity
    • Negishi H, Osawa T, Ogami K et al.: A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity. Proc. Natl Acad. Sci. USA 105, 20446-20451 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 20446-20451
    • Negishi, H.1    Osawa, T.2    Ogami, K.3
  • 21
    • 49149119966 scopus 로고    scopus 로고
    • Effective chemokine secretion by dendritic cells and expansion of cross-presenting CD4 CD8 dendritic cells define a protective phenotype in the mouse model of coxsackievirus myocarditis
    • Weinzierl AO, Szalay G, Wolburg H et al.: Effective chemokine secretion by dendritic cells and expansion of cross-presenting CD4-/ CD8+ dendritic cells define a protective phenotype in the mouse model of coxsackievirus myocarditis. J. Virol. 82, 8149-8160 (2008).
    • (2008) J. Virol. , vol.82 , pp. 8149-8160
    • Weinzierl, A.O.1    Szalay, G.2    Wolburg, H.3
  • 22
    • 58149458888 scopus 로고    scopus 로고
    • Toll like receptor 3 signaling on macrophages is required for survival following coxsackievirus B4 infection
    • Richer MJ, Lavallee DJ, Shanina I, Horwitz MS: Toll-like receptor 3 signaling on macrophages is required for survival following coxsackievirus B4 infection. PLoS ONE 4, E4127 (2009).
    • (2009) PLoS ONE , vol.4
    • Richer, M.J.1    Lavallee, D.J.2    Shanina, I.3    Horwitz, M.S.4
  • 23
    • 22744457707 scopus 로고    scopus 로고
    • Human cardiac inflammatory responses triggered by coxsackie B viruses are mainly toll like receptor TLR 8 dependent
    • Triantafilou K, Orthopoulos G, Vakakis E et al.: Human cardiac inflammatory responses triggered by coxsackie B viruses are mainly Toll-like receptor (TLR) 8-dependent. Cell. Microbiol. 7, 1117-1126 (2005).
    • (2005) Cell. Microbiol. , vol.7 , pp. 1117-1126
    • Triantafilou, K.1    Orthopoulos, G.2    Vakakis, E.3
  • 24
    • 1542317578 scopus 로고    scopus 로고
    • Species specific recognition of single stranded RNA via toll like receptor 7 and 8
    • Heil F, Hemmi H, Hochrein H et al.: Species-specific recognition of single-stranded RNA via Toll-like receptor 7 and 8. Science 303, 1526-1529 (2004).
    • (2004) Science , vol.303 , pp. 1526-1529
    • Heil, F.1    Hemmi, H.2    Hochrein, H.3
  • 25
    • 74449089424 scopus 로고    scopus 로고
    • A five amino acid motif in the undefined region of the TLR8 ectodomain is required for species specific ligand recognition
    • Liu J, Xu C, Hsu LC, Luo Y, Xiang R, Chuang TH: A five-amino-acid motif in the undefined region of the TLR8 ectodomain is required for species-specific ligand recognition. Mol. Immunol. 47, 1083-1090 (2010)
    • (2010) Mol. Immunol. , vol.47 , pp. 1083-1090
    • Liu, J.1    Xu, C.2    Hsu, L.C.3    Luo, Y.4    Xiang, R.5    Chuang, T.H.6
  • 26
    • 61349086647 scopus 로고    scopus 로고
    • Variation matters: TLR structure and species specific pathogen recognition
    • Werling D, Jann OC, Offord V, Glass EJ, Coffey TJ: Variation matters: TLR structure and species-specific pathogen recognition. Trends Immunol. 30, 124-130 (2009).
    • (2009) Trends Immunol , vol.30 , pp. 124-130
    • Werling, D.1    Jann, O.C.2    Offord, V.3    Glass, E.J.4    Coffey, T.J.5
  • 27
    • 23744442371 scopus 로고    scopus 로고
    • TLR 2 gene arg753gln polymorphism is strongly associated with acute rheumatic fever in children
    • Berdeli A, Celik HA, Ozyurek R, Dogrusoz B, Aydin HH: TLR-2 gene Arg753Gln polymorphism is strongly associated with acute rheumatic fever in children. J. Mol. Med. 83, 535-541 (2005).
    • (2005) J. Mol. Med. , vol.83 , pp. 535-541
    • Berdeli, A.1    Celik, H.A.2    Ozyurek, R.3    Dogrusoz, B.4    Aydin, H.H.5
  • 28
    • 33645997366 scopus 로고    scopus 로고
    • Characterization of early steps in the poliovirus infection process: Receptor decorated liposomes induce conversion of the virus to membrane anchored entry intermediate particles
    • Tuthill TJ, Bubeck D, Rowlands DJ, Hogle JM: Characterization of early steps in the poliovirus infection process: receptor-decorated liposomes induce conversion of the virus to membrane-anchored entry-intermediate particles. J. Virol. 80, 172-180 (2006).
    • (2006) J. Virol. , vol.80 , pp. 172-180
    • Tuthill, T.J.1    Bubeck, D.2    Rowlands, D.J.3    Hogle, J.M.4
  • 30
    • 10644287588 scopus 로고    scopus 로고
    • Interaction with coxsackievirus and adenovirus receptor but not with decay-accelerating factor DAF induces a-particle formation in a DAF-binding coxsackievirus b3 isolate
    • Milstone AM, Petrella J, Sanchez MD, Mahmud M, Whitbeck JC, Bergelson JM: Interaction with coxsackievirus and adenovirus receptor, but not with decay-accelerating factor (DAF), induces A-particle formation in a DAF-binding coxsackievirus B3 isolate. J. Virol. 79, 655-660 (2005).
    • (2005) J. Virol. , vol.79 , pp. 655-660
    • Milstone, A.M.1    Petrella, J.2    Sanchez, M.D.3    Mahmud, M.4    Whitbeck, J.C.5    Bergelson, J.M.6
  • 31
    • 30344475861 scopus 로고    scopus 로고
    • Virus induced abl and fyn kinase signals permit coxsackievirus entry through epithelial tight junctions
    • Coyne CB, Bergelson JM: Virus-induced Abl and Fyn kinase signals permit coxsackievirus entry through epithelial tight junctions. Cell 124, 119-131 (2006).
    • (2006) Cell , vol.124 , pp. 119-131
    • Coyne, C.B.1    Bergelson, J.M.2
  • 32
    • 34548433948 scopus 로고    scopus 로고
    • Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5
    • Coyne CB, Shen L, Turner JR, Bergelson JM: Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5. Cell Host Microbe 2, 181-192 (2007).
    • (2007) Cell Host Microbe , vol.2 , pp. 181-192
    • Coyne, C.B.1    Shen, L.2    Turner, J.R.3    Bergelson, J.M.4
  • 33
    • 70350277393 scopus 로고    scopus 로고
    • Dynamin and lipid raft dependent entry of decay accelerating factor DAF binding and non DAF binding coxsackieviruses into nonpolarized cells
    • Patel KP, Coyne CB, Bergelson JM: Dynamin-and lipid raft-dependent entry of decay-accelerating factor (DAF)-binding and non-DAF-binding coxsackieviruses into nonpolarized cells. J. Virol. 83, 11064-11077 (2009).
    • (2009) J. Virol. , vol.83 , pp. 11064-11077
    • Patel, K.P.1    Coyne, C.B.2    Bergelson, J.M.3
  • 34
    • 33947258375 scopus 로고    scopus 로고
    • Cutting edge: Antibody mediated TLR7 dependent recognition of viral RNA
    • Wang JP, Asher DR, Chan M, Kurt-Jones EA, Finberg RW: Cutting edge: antibody-mediated TLR7-dependent recognition of viral RNA. J. Immunol. 178, 3363-3367 (2007).
    • (2007) J. Immunol. , vol.178 , pp. 3363-3367
    • Wang, J.P.1    Asher, D.R.2    Chan, M.3    Kurt-Jones, E.A.4    Finberg, R.W.5
  • 35
    • 77951256153 scopus 로고    scopus 로고
    • Autophagy in infection
    • Deretic V: Autophagy in infection. Curr. Opin. Cell Biol. 22(2), 252-262 (2010).
    • (2010) Curr. Opin. Cell Biol. , vol.22 , Issue.2 , pp. 252-262
    • Deretic, V.1
  • 36
    • 67649607465 scopus 로고    scopus 로고
    • Autophagy immunity and microbial adaptations
    • Deretic V, Levine B: Autophagy, immunity, and microbial adaptations. Cell Host Microbe 5, 527-549 (2009).
    • (2009) Cell Host Microbe , vol.5 , pp. 527-549
    • Deretic, V.1    Levine, B.2
  • 38
    • 33947134377 scopus 로고    scopus 로고
    • Autophagy dependent viral recognition by plasmacytoid dendritic cells
    • Lee HK, Lund JM, Ramanathan B, Mizushima N, Iwasaki A: Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science 315, 1398-1401 (2007).
    • (2007) Science , vol.315 , pp. 1398-1401
    • Lee, H.K.1    Lund, J.M.2    Ramanathan, B.3    Mizushima, N.4    Iwasaki, A.5
  • 40
    • 0000115806 scopus 로고
    • Electron microscopic study of the formation of poliovirus
    • Dales S, Eggers HJ, Tamm I, Palade GE: Electron microscopic study of the formation of poliovirus. Virology 26, 379-389 (1965).
    • (1965) Virology , vol.26 , pp. 379-389
    • Dales, S.1    Eggers, H.J.2    Tamm, I.3    Palade, G.E.4
  • 41
    • 0029794678 scopus 로고    scopus 로고
    • Cellular origin and ultrastructure of membranes induced during poliovirus infection
    • Schlegel A, Giddings TH Jr, Ladinsky MS, Kirkegaard K: Cellular origin and ultrastructure of membranes induced during poliovirus infection. J. Virol. 70, 6576-6588 (1996).
    • (1996) J. Virol. , vol.70 , pp. 6576-6588
    • Schlegel, A.1    Giddings Jr., T.H.2    Ladinsky, M.S.3    Kirkegaard, K.4
  • 42
    • 0033798416 scopus 로고    scopus 로고
    • Remodeling the endoplasmic reticulum by poliovirus infection and by individual viral proteins: An autophagy like origin for virus induced vesicles
    • Suhy DA, Giddings TH Jr, Kirkegaard K: Remodeling the endoplasmic reticulum by poliovirus infection and by individual viral proteins: an autophagy-like origin for virus-induced vesicles. J. Virol. 74, 8953-8965 (2000).
    • (2000) J. Virol. , vol.74 , pp. 8953-8965
    • Suhy, D.A.1    Giddings Jr., T.H.2    Kirkegaard, K.3
  • 43
    • 41449113692 scopus 로고    scopus 로고
    • Potential subversion of autophagosomal pathway by picornaviruses
    • Taylor MP, Kirkegaard K: Potential subversion of autophagosomal pathway by picornaviruses. Autophagy 4, 286-289 (2008).
    • (2008) Autophagy , vol.4 , pp. 286-289
    • Taylor, M.P.1    Kirkegaard, K.2
  • 44
    • 36049014444 scopus 로고    scopus 로고
    • Modification of cellular autophagy protein LC3 by poliovirus
    • Taylor MP, Kirkegaard K: Modification of cellular autophagy protein LC3 by poliovirus. J. Virol. 81, 12543-12553 (2007).
    • (2007) J. Virol. , vol.81 , pp. 12543-12553
    • Taylor, M.P.1    Kirkegaard, K.2
  • 45
    • 0016713739 scopus 로고
    • Spherical aggregates of coxsackie B4 virus particles in mouse pancreas
    • Harb JM, Burch GE: Spherical aggregates of coxsackie B4 virus particles in mouse pancreas. Beitr. Pathol. 156, 122-127 (1975).
    • (1975) Beitr. Pathol. , vol.156 , pp. 122-127
    • Harb, J.M.1    Burch, G.E.2
  • 46
    • 50949133741 scopus 로고    scopus 로고
    • Autophagosome supports coxsackievirus B3 replication in host cells
    • Wong J, Zhang J, Si X et al.: Autophagosome supports coxsackievirus B3 replication in host cells. J. Virol. 82, 9143-9153 (2008).
    • (2008) J. Virol. , vol.82 , pp. 9143-9153
    • Wong, J.1    Zhang, J.2    Si, X.3
  • 47
    • 56449116096 scopus 로고    scopus 로고
    • Coxsackievirus B4 uses autophagy for replication after calpain activation in rat primary neurons
    • Yoon SY, Ha YE, Choi JE et al.: Coxsackievirus B4 uses autophagy for replication after calpain activation in rat primary neurons. J. Virol. 82, 11976-11978 (2008).
    • (2008) J. Virol. , vol.82 , pp. 11976-11978
    • Yoon, S.Y.1    Ha, Y.E.2    Choi, J.E.3
  • 48
    • 21344452171 scopus 로고    scopus 로고
    • Subversion of cellular autophagosomal machinery by RNA viruses
    • Jackson WT, Giddings TH Jr, Taylor MP et al.: Subversion of cellular autophagosomal machinery by RNA viruses. PLoS Biol. 3, e156 (2005).
    • (2005) PLoS Biol. , vol.3
    • Jackson, W.T.1    Giddings Jr., T.H.2    Taylor, M.P.3
  • 49
    • 65249090334 scopus 로고    scopus 로고
    • Autophagy is involved in influenza a virus replication
    • Zhou Z, Jiang X, Liu D et al.: Autophagy is involved in influenza A virus replication. Autophagy 5, 321-328 (2009).
    • (2009) Autophagy , vol.5 , pp. 321-328
    • Zhou, Z.1    Jiang, X.2    Liu, D.3
  • 50
    • 77749292148 scopus 로고    scopus 로고
    • The early autophagic pathway is activated by hepatitis b virus and required for viral DNA replication
    • Sir D, Tian Y, Chen WL, Ann DK, Yen TS, Ou JH: The early autophagic pathway is activated by hepatitis B virus and required for viral DNA replication. Proc. Natl Acad. Sci. USA 107, 4383-4388 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 4383-4388
    • Sir, D.1    Tian, Y.2    Chen, W.L.3    Ann, D.K.4    Yen, T.S.5    Ou, J.H.6
  • 51
    • 69549135689 scopus 로고    scopus 로고
    • The autophagy machinery is required to initiate hepatitis c virus replication
    • Dreux M, Gastaminza P, Wieland SF, Chisari FV: The autophagy machinery is required to initiate hepatitis C virus replication. Proc. Natl Acad. Sci. USA 106, 14046-14051 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 14046-14051
    • Dreux, M.1    Gastaminza, P.2    Wieland, S.F.3    Chisari, F.V.4
  • 52
    • 33646555141 scopus 로고    scopus 로고
    • Aggresomes and autophagy generate sites for virus replication
    • Wileman T: Aggresomes and autophagy generate sites for virus replication. Science 312, 875-878 (2006).
    • (2006) Science , vol.312 , pp. 875-878
    • Wileman, T.1
  • 53
    • 69449103157 scopus 로고    scopus 로고
    • Viruses and arrested autophagosome development
    • Taylor MP, Jackson WT: Viruses and arrested autophagosome development. Autophagy 5, 870-871 (2009).
    • (2009) Autophagy , vol.5 , pp. 870-871
    • Taylor, M.P.1    Jackson, W.T.2
  • 54
    • 67449097826 scopus 로고    scopus 로고
    • Role of microtubules in extracellular release of poliovirus
    • Taylor MP, Burgon TB, Kirkegaard K, Jackson WT: Role of microtubules in extracellular release of poliovirus. J. Virol. 83, 6599-6609 (2009).
    • (2009) J. Virol. , vol.83 , pp. 6599-6609
    • Taylor, M.P.1    Burgon, T.B.2    Kirkegaard, K.3    Jackson, W.T.4
  • 55
    • 72649105081 scopus 로고    scopus 로고
    • Matrix protein 2 of influenza a virus blocks autophagosome fusion with lysosomes
    • Gannage M, Dormann D, Albrecht R et al.: Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes. Cell Host Microbe 6, 367-380 (2009).
    • (2009) Cell Host Microbe , vol.6 , pp. 367-380
    • Gannage, M.1    Dormann, D.2    Albrecht, R.3
  • 56
    • 67649585835 scopus 로고    scopus 로고
    • Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages
    • Kyei GB, Dinkins C, Davis AS et al.: Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages. J. Cell Biol. 186, 255-268 (2009).
    • (2009) J. Cell Biol. , vol.186 , pp. 255-268
    • Kyei, G.B.1    Dinkins, C.2    Davis, A.S.3
  • 57
    • 31344476404 scopus 로고    scopus 로고
    • Recognition of double stranded RNA by human toll like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH
    • de Bouteiller O, Merck E, Hasan UA et al.: Recognition of double-stranded RNA by human Toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH. J. Biol. Chem. 280, 38133-38145 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 38133-38145
    • De Bouteiller, O.1    Merck, E.2    Hasan, U.A.3
  • 58
    • 40749098665 scopus 로고    scopus 로고
    • Unc93b1 delivers nucleotide sensing toll like receptors to endolysosomes
    • Kim YM, Brinkmann MM, Paquet ME, Ploegh HL: UNC93B1 delivers nucleotide-sensing Toll-like receptors to endolysosomes. Nature 452, 234-238 (2008).
    • (2008) Nature , vol.452 , pp. 234-238
    • Kim, Y.M.1    Brinkmann, M.M.2    Paquet, M.E.3    Ploegh, H.L.4
  • 59
    • 59849109401 scopus 로고    scopus 로고
    • Real time measurement of endosomal acidification by a novel genetically encoded biosensor
    • Serresi M, Bizzarri R, Cardarelli F, Beltram F: Real-time measurement of endosomal acidification by a novel genetically encoded biosensor. Anal. Bioanal. Chem. 393, 1123-1133 (2009).
    • (2009) Anal. Bioanal. Chem. , vol.393 , pp. 1123-1133
    • Serresi, M.1    Bizzarri, R.2    Cardarelli, F.3    Beltram, F.4
  • 60
    • 0038651180 scopus 로고    scopus 로고
    • Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of toll like receptor 7
    • Lee J, Chuang TH, Redecke V et al.: Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc. Natl Acad. Sci. USA 100, 6646-6651 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 6646-6651
    • Lee, J.1    Chuang, T.H.2    Redecke, V.3
  • 61
    • 1542317550 scopus 로고    scopus 로고
    • Reis e sousa c: Innate antiviral responses by means of TLR7 mediated recognition of single stranded RNA
    • Diebold SS, Kaisho T, Hemmi H, Akira S, Reis e Sousa C: Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303, 1529-1531 (2004).
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4
  • 62
    • 10744219675 scopus 로고    scopus 로고
    • TLR9 signals after translocating from the ER to CpG DNA in the lysosome
    • Latz E, Schoenemeyer A, Visintin A et al.: TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat. Immunol. 5, 190-198 (2004).
    • (2004) Nat. Immunol , vol.5 , pp. 190-198
    • Latz, E.1    Schoenemeyer, A.2    Visintin, A.3
  • 63
    • 4644330955 scopus 로고    scopus 로고
    • Toll like receptor 9 binds single stranded CpG DNA in a sequence and pH dependent manner
    • Rutz M, Metzger J, Gellert T et al.: Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence-and pH-dependent manner. Eur. J. Immunol. 34, 2541-2550 (2004).
    • (2004) Eur. J. Immunol. , vol.34 , pp. 2541-2550
    • Rutz, M.1    Metzger, J.2    Gellert, T.3
  • 64
    • 70449477746 scopus 로고    scopus 로고
    • Critical role for asparagine endopeptidase in endocytic toll like receptor signaling in dendritic cells
    • Sepulveda FE, Maschalidi S, Colisson R et al.: Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells. Immunity 31, 737-748 (2009)
    • (2009) Immunity , vol.31 , pp. 737-748
    • Sepulveda, F.E.1    Maschalidi, S.2    Colisson, R.3
  • 65
    • 76949097340 scopus 로고    scopus 로고
    • Quantitative proteomics reveals subset-specific viral recognition in dendritic cells
    • Luber CA, Cox J, Lauterbach H et al.: Quantitative proteomics reveals subset-specific viral recognition in dendritic cells. Immunity. 32, 279-289 (2010).
    • (2010) Immunity , vol.32 , pp. 279-289
    • Luber, C.A.1    Cox, J.2    Lauterbach, H.3
  • 66
    • 65249135027 scopus 로고    scopus 로고
    • Retinoic acid induced gene 1 RIG I associates with the actin cytoskeleton via caspase activation and recruitment domain dependent interactions
    • Mukherjee A, Morosky SA, Shen L et al.: Retinoic acid-induced gene-1 (RIG-I) associates with the actin cytoskeleton via caspase activation and recruitment domain-dependent interactions. J. Biol. Chem. 284, 6486-6494 (2009).
    • (2009) J. Biol. Chem. , vol.284 , pp. 6486-6494
    • Mukherjee, A.1    Morosky, S.A.2    Shen, L.3
  • 67
    • 33646342149 scopus 로고    scopus 로고
    • Differential roles of MDA5 and RIG I helicases in the recognition of RNA viruses
    • Kato H, Takeuchi O, Sato S et al.: Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441, 101-105 (2006).
    • (2006) Nature , vol.441 , pp. 101-105
    • Kato, H.1    Takeuchi, O.2    Sato, S.3
  • 68
    • 37349052379 scopus 로고    scopus 로고
    • Distinct RIG I and MDA5 signaling by RNA viruses in innate immunity
    • Loo YM, Fornek J, Crochet N et al.: Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity. J. Virol. 82, 335-345 (2008).
    • (2008) J. Virol. , vol.82 , pp. 335-345
    • Loo, Y.M.1    Fornek, J.2    Crochet, N.3
  • 69
    • 77952503750 scopus 로고    scopus 로고
    • Peroxisomes are signaling platforms for antiviral innate immunity
    • Dixit E, Boulant S, Zhang Y et al.: Peroxisomes are signaling platforms for antiviral innate immunity. Cell 141, 668-681 (2010).
    • (2010) Cell , vol.141 , pp. 668-681
    • Dixit, E.1    Boulant, S.2    Zhang, Y.3
  • 70
    • 24144461689 scopus 로고    scopus 로고
    • Identification and characterization of Mavs a mitochondrial antiviral signaling protein that activates NF kB and IRF 3
    • Seth RB, Sun L, Ea CK, Chen ZJ: Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kB and IRF 3. Cell 122, 669-682 (2005).
    • (2005) Cell , vol.122 , pp. 669-682
    • Seth, R.B.1    Sun, L.2    Ea, C.K.3    Chen, Z.J.4
  • 71
    • 24944538819 scopus 로고    scopus 로고
    • Visa is an adapter protein required for virus triggered IFN b signaling
    • Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB: VISA is an adapter protein required for virus-triggered IFN-b signaling. Mol. Cell 19, 727-740 (2005).
    • (2005) Mol. Cell , vol.19 , pp. 727-740
    • Xu, L.G.1    Wang, Y.Y.2    Han, K.J.3    Li, L.Y.4    Zhai, Z.5    Shu, H.B.6
  • 72
    • 27144440476 scopus 로고    scopus 로고
    • Cardif is an adaptor protein in the RIG I antiviral pathway and is targeted by hepatitis c virus
    • Meylan E, Curran J, Hofmann K et al.: Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437, 1167-1172 (2005).
    • (2005) Nature , vol.437 , pp. 1167-1172
    • Meylan, E.1    Curran, J.2    Hofmann, K.3
  • 73
    • 27144440523 scopus 로고    scopus 로고
    • IPS 1 an adaptor triggering RIG I and Mda5 mediated type I interferon induction
    • Kawai T, Takahashi K, Sato S et al.: IPS-1, an adaptor triggering RIG-I-and Mda5-mediated type I interferon induction. Nat. Immunol. 6, 981-988 (2005).
    • (2005) Nat. Immunol , vol.6 , pp. 981-988
    • Kawai, T.1    Takahashi, K.2    Sato, S.3
  • 74
    • 33750976374 scopus 로고    scopus 로고
    • 5 triphosphate RNA is the ligand for RIG I
    • Hornung V, Ellegast J, Kim S et al.: 5-triphosphate RNA is the ligand for RIG-I. Science 314, 994-997 (2006).
    • (2006) Science , vol.314 , pp. 994-997
    • Hornung, V.1    Ellegast, J.2    Kim, S.3
  • 75
    • 33750984771 scopus 로고    scopus 로고
    • RIG I mediated antiviral responses to single stranded RNA bearing 5 phosphates
    • Pichlmair A, Schulz O, Tan CP et al.: RIG-I-mediated antiviral responses to single-stranded RNA bearing 5-phosphates. Science 314, 997-1001 (2006).
    • (2006) Science , vol.314 , pp. 997-1001
    • Pichlmair, A.1    Schulz, O.2    Tan, C.P.3
  • 77
    • 34548449917 scopus 로고    scopus 로고
    • Poliovirus entry into human brain microvascular cells requires receptor-induced activation of SHP 2
    • Coyne CB, Kim KS, Bergelson JM: Poliovirus entry into human brain microvascular cells requires receptor-induced activation of SHP-2. EMBO J. 26, 4016-4028 (2007).
    • (2007) EMBO J. , vol.26 , pp. 4016-4028
    • Coyne, C.B.1    Kim, K.S.2    Bergelson, J.M.3
  • 78
    • 34447100268 scopus 로고    scopus 로고
    • Coxsackievirus B3 affects endothelial tight junctions: Possible relationship to ZO 1 and F actin as well as p38 MAPK activity
    • Ju Y, Wang T, Li Y, Xin W, Wang S, Li J: Coxsackievirus B3 affects endothelial tight junctions: possible relationship to ZO-1 and F-actin, as well as p38 MAPK activity. Cell Biol. Int. 31, 1207-1213 (2007).
    • (2007) Cell Biol. Int. , vol.31 , pp. 1207-1213
    • Ju, Y.1    Wang, T.2    Li, Y.3    Xin, W.4    Wang, S.5    Li, J.6
  • 79
    • 33744791510 scopus 로고    scopus 로고
    • Essential role of MDA 5 in type I IFN responses to poly riboinosinic polyribocytidylic acid and encephalomyocarditis picornavirus
    • Gitlin L, Barchet W, Gilfillan S et al.: Essential role of MDA-5 in type I IFN responses to poly riboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus. Proc. Natl Acad. Sci. USA 103, 8459-8464 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 8459-8464
    • Gitlin, L.1    Barchet, W.2    Gilfillan, S.3
  • 80
    • 33644752821 scopus 로고    scopus 로고
    • West nile virus evades activation of interferon regulatory factor 3 through RIG I dependent and independent pathways without antagonizing host defense signaling
    • Fredericksen BL, Gale M Jr: West Nile virus evades activation of interferon regulatory factor 3 through RIG-I-dependent and -independent pathways without antagonizing host defense signaling. J. Virol. 80, 2913-2923 (2006).
    • (2006) J. Virol. , vol.80 , pp. 2913-2923
    • Fredericksen, B.L.1    Gale Jr., M.2
  • 81
    • 37849045856 scopus 로고    scopus 로고
    • Establishment and maintenance of the innate antiviral response to west nile virus involves both RIG-I and MDA5 signaling through IPS-1
    • Fredericksen BL, Keller BC, Fornek J, Katze MG, Gale M Jr: Establishment and maintenance of the innate antiviral response to West Nile Virus involves both RIG-I and MDA5 signaling through IPS-1. J. Virol. 82, 609-616 (2008).
    • (2008) J. Virol. , vol.82 , pp. 609-616
    • Fredericksen, B.L.1    Keller, B.C.2    Fornek, J.3    Katze, M.G.4    Gale Jr., M.5
  • 82
    • 46949097299 scopus 로고    scopus 로고
    • Length dependent recognition of doublestranded ribonucleic acids by retinoic acid inducible gene I and melanoma differentiation associated gene 5
    • Kato H, Takeuchi O, Mikamo-Satoh E et al.: Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5. J. Exp. Med. 205, 1601-1610 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 1601-1610
    • Kato, H.1    Takeuchi, O.2    Mikamo-Satoh, E.3
  • 83
    • 44449125726 scopus 로고    scopus 로고
    • MDA5 participates in the detection of paramyxovirus infection and is essential for the early activation of dendritic cells in response to sendai virus defective interfering particles
    • Yount JS, Gitlin L, Moran TM, Lopez CB: MDA5 participates in the detection of paramyxovirus infection and is essential for the early activation of dendritic cells in response to Sendai virus defective interfering particles. J. Immunol. 180, 4910-4918 (2008).
    • (2008) J. Immunol , vol.180 , pp. 4910-4918
    • Yount, J.S.1    Gitlin, L.2    Moran, T.M.3    Lopez, C.B.4
  • 84
    • 77649221014 scopus 로고    scopus 로고
    • Melanoma differentiation associated gene 5 MDA5 is involved in the innate immune response to paramyxoviridae infection in vivo
    • Gitlin L, Benoit L, Song C et al.: Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo. PLoS Path. 6, E1000734 (2010).
    • (2010) PLoS Path. , vol.6
    • Gitlin, L.1    Benoit, L.2    Song, C.3
  • 86
    • 72849147109 scopus 로고    scopus 로고
    • Both RIG I and MDA5 RNA helicases contribute to the induction of a b interferon in measles virus infected human cells
    • Ikegame S, Takeda M, Ohno S, Nakatsu Y, Nakanishi Y, Yanagi Y: Both RIG-I and MDA5 RNA helicases contribute to the induction of a/b interferon in measles virus-infected human cells. J. Virol. 84, 372-379 (2010).
    • (2010) J. Virol. , vol.84 , pp. 372-379
    • Ikegame, S.1    Takeda, M.2    Ohno, S.3    Nakatsu, Y.4    Nakanishi, Y.5    Yanagi, Y.6
  • 88
    • 77950924630 scopus 로고    scopus 로고
    • Melanoma differentiation associated protein 5 MDA 5 limits early viral replication but is not essential for the induction of type 1 interferons after coxsackievirus infection
    • Huhn MH, McCartney SA, Lind K, Svedin E, Colonna M, Flodstrom-Tullberg M: Melanoma differentiation-associated protein-5 (MDA-5) limits early viral replication but is not essential for the induction of type 1 interferons after coxsackievirus infection. Virology 401, 42-48 (2010).
    • (2010) Virology , vol.401 , pp. 42-48
    • Huhn, M.H.1    McCartney, S.A.2    Lind, K.3    Svedin, E.4    Colonna, M.5    Flodstrom-Tullberg, M.6
  • 89
    • 34247127075 scopus 로고    scopus 로고
    • MDA 5 is cleaved in poliovirus infected cells
    • Barral PM, Morrison JM, Drahos J et al.: MDA-5 is cleaved in poliovirus-infected cells. J. Virol. 81, 3677-3684 (2007).
    • (2007) J. Virol. , vol.81 , pp. 3677-3684
    • Barral, P.M.1    Morrison, J.M.2    Drahos, J.3
  • 90
    • 33846307026 scopus 로고    scopus 로고
    • Regulation of innate antiviral defenses through a shared repressor domain in RIG I and LGP2
    • Saito T, Hirai R, Loo YM et al.: Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2. Proc. Natl Acad. Sci. USA 104, 582-587 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 582-587
    • Saito, T.1    Hirai, R.2    Loo, Y.M.3
  • 91
    • 33845431988 scopus 로고    scopus 로고
    • RNA and virus independent inhibition of antiviral signaling by RNA helicase LGP2
    • Komuro A, Horvath CM: RNA-and virus-independent inhibition of antiviral signaling by RNA helicase LGP2. J. Virol. 80, 12332-12342 (2006).
    • (2006) J. Virol. , vol.80 , pp. 12332-12342
    • Komuro, A.1    Horvath, C.M.2
  • 92
    • 26844503987 scopus 로고    scopus 로고
    • The RNA helicase Lgp2 inhibits TLR independent sensing of viral replication by retinoic acid inducible gene I
    • Rothenfusser S, Goutagny N, DiPerna G et al.: The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I. J. Immunol. 175, 5260-5268 (2005).
    • (2005) J. Immunol , vol.175 , pp. 5260-5268
    • Rothenfusser, S.1    Goutagny, N.2    DiPerna, G.3
  • 93
    • 34248168157 scopus 로고    scopus 로고
    • Loss of DExD H box RNA helicase LGP2 manifests disparate antiviral responses
    • Venkataraman T, Valdes M, Elsby R et al.: Loss of DExD/H box RNA helicase LGP2 manifests disparate antiviral responses. J. Immunol. 178, 6444-6455 (2007).
    • (2007) J. Immunol , vol.178 , pp. 6444-6455
    • Venkataraman, T.1    Valdes, M.2    Elsby, R.3
  • 94
    • 76549109497 scopus 로고    scopus 로고
    • LGP2 is a positive regulator of RIG I and MDA5 mediated antiviral responses
    • Satoh T, Kato H, Kumagai Y et al.: LGP2 is a positive regulator of RIG-I-and MDA5-mediated antiviral responses. Proc. Natl Acad. Sci. USA 107, 1512-1517 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 1512-1517
    • Satoh, T.1    Kato, H.2    Kumagai, Y.3
  • 95
    • 34248654077 scopus 로고    scopus 로고
    • Echovirus infection causes rapid loss of function and cell death in human dendritic cells
    • Kramer M, Schulte BM, Toonen LW et al.: Echovirus infection causes rapid loss-of-function and cell death in human dendritic cells. Cell. Microbiol. 9, 1507-1518 (2007).
    • (2007) Cell. Microbiol , vol.9 , pp. 1507-1518
    • Kramer, M.1    Schulte, B.M.2    Toonen, L.W.3
  • 96
    • 40149086825 scopus 로고    scopus 로고
    • Phagocytosis of picornavirus infected cells induces an RNA dependent antiviral state in human dendritic cells
    • Kramer M, Schulte BM, Toonen LW et al.: Phagocytosis of picornavirus-infected cells induces an RNA-dependent antiviral state in human dendritic cells. J. Virol. 82, 2930-2937 (2008).
    • (2008) J. Virol. , vol.82 , pp. 2930-2937
    • Kramer, M.1    Schulte, B.M.2    Toonen, L.W.3
  • 97
    • 33646592188 scopus 로고    scopus 로고
    • The specific and essential role of MAVS in antiviral innate immune responses
    • Sun Q, Sun L, Liu HH et al.: The specific and essential role of MAVS in antiviral innate immune responses. Immunity 24, 633-642 (2006).
    • (2006) Immunity , vol.24 , pp. 633-642
    • Sun, Q.1    Sun, L.2    Liu, H.H.3
  • 98
    • 34249855382 scopus 로고    scopus 로고
    • Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor
    • Yang Y, Liang Y, Qu L et al.: Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor. Proc. Natl Acad. Sci. USA 104, 7253-7258 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 7253-7258
    • Yang, Y.1    Liang, Y.2    Qu, L.3
  • 99
    • 84875981860 scopus 로고    scopus 로고
    • MAVS mediated apoptosis and its inhibition by viral proteins
    • Lei Y, Moore CB, Liesman RM et al.: MAVS-mediated apoptosis and its inhibition by viral proteins. PLoS ONE 4, E5466 (2009).
    • (2009) PLoS ONE , vol.4
    • Lei, Y.1    Moore, C.B.2    Liesman, R.M.3
  • 100
    • 77649202152 scopus 로고    scopus 로고
    • The interferon stimulator mitochondrial antiviral signaling protein facilitates cell death by disrupting the mitochondrial membrane potential and by activating caspases
    • Yu CY, Chiang RL, Chang TH, Liao CL, Lin YL: The interferon stimulator mitochondrial antiviral signaling protein facilitates cell death by disrupting the mitochondrial membrane potential and by activating caspases. J. Virol. 84, 2421-2431 (2010).
    • (2010) J. Virol. , vol.84 , pp. 2421-2431
    • Yu, C.Y.1    Chiang, R.L.2    Chang, T.H.3    Liao, C.L.4    Lin, Y.L.5
  • 101
    • 75949098312 scopus 로고    scopus 로고
    • Mitochondrial dynamics regulate the RIG I like receptor antiviral pathway
    • Castanier C, Garcin D, Vazquez A, Arnoult D: Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway. EMBO Rep. 11, 133-138 (2010).
    • (2010) EMBO Rep. , vol.11 , pp. 133-138
    • Castanier, C.1    Garcin, D.2    Vazquez, A.3    Arnoult, D.4
  • 102
    • 36048962438 scopus 로고    scopus 로고
    • Control of toll like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation
    • Deane JA, Pisitkun P, Barrett RS et al.: Control of Toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity 27, 801-810 (2007).
    • (2007) Immunity , vol.27 , pp. 801-810
    • Deane, J.A.1    Pisitkun, P.2    Barrett, R.S.3
  • 103
    • 33748472865 scopus 로고    scopus 로고
    • Toll like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus
    • Christensen SR, Shupe J, Nickerson K, Kashgarian M, Flavell RA, Shlomchik MJ: Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. Immunity 25, 417-428 (2006).
    • (2006) Immunity , vol.25 , pp. 417-428
    • Christensen, S.R.1    Shupe, J.2    Nickerson, K.3    Kashgarian, M.4    Flavell, R.A.5    Shlomchik, M.J.6
  • 104
    • 16644377980 scopus 로고    scopus 로고
    • Apoptosis and mitochondrial dysfunction in lymphocytes of patients with systemic lupus erythematosus
    • Perl A, Nagy G, Gergely P, Puskas F, Qian Y, Banki K: Apoptosis and mitochondrial dysfunction in lymphocytes of patients with systemic lupus erythematosus. Methods Mol. Med. 102, 87-114 (2004).
    • (2004) Methods Mol. Med. , vol.102 , pp. 87-114
    • Perl, A.1    Nagy, G.2    Gergely, P.3    Puskas, F.4    Qian, Y.5    Banki, K.6
  • 105
    • 62749122727 scopus 로고    scopus 로고
    • Mitochondrial DNA polymorphisms are associated with susceptibility and phenotype of systemic lupus erythematosus
    • Jonsen A, Yu X, Truedsson L et al.: Mitochondrial DNA polymorphisms are associated with susceptibility and phenotype of systemic lupus erythematosus. Lupus 18, 309-312 (2009).
    • (2009) Lupus , vol.18 , pp. 309-312
    • Jonsen, A.1    Yu, X.2    Truedsson, L.3
  • 106
    • 0023157113 scopus 로고
    • Autoantibodies specific for the cardiac myosin isoform are found in mice susceptible to coxsackievirus B3-induced myocarditis
    • Neu N, Beisel KW, Traystman MD, Rose NR, Craig SW: Autoantibodies specific for the cardiac myosin isoform are found in mice susceptible to coxsackievirus B3-induced myocarditis. J. Immunol. 138, 2488-2492 (1987).
    • (1987) J. Immunol , vol.138 , pp. 2488-2492
    • Neu, N.1    Beisel, K.W.2    Traystman, M.D.3    Rose, N.R.4    Craig, S.W.5
  • 109
    • 0021248632 scopus 로고
    • Coxsackievirus B 3 myocarditis in Balb c mice evidence for autoimmunity to myocyte antigens
    • Huber SA, Lodge PA: Coxsackievirus B-3 myocarditis in Balb/c mice. Evidence for autoimmunity to myocyte antigens. Am. J. Pathol. 116, 21-29 (1984).
    • (1984) Am. J. Pathol. , vol.116 , pp. 21-29
    • Huber, S.A.1    Lodge, P.A.2
  • 110
    • 0021991034 scopus 로고
    • Immunopathogenesis of experimental coxsackievirus induced myocarditis: Role of autoimmunity
    • Huber SA, Lyden DC, Lodge PA: Immunopathogenesis of experimental coxsackievirus induced myocarditis: role of autoimmunity. Herz 10, 1-7 (1985).
    • (1985) Herz , vol.10 , pp. 1-7
    • Huber, S.A.1    Lyden, D.C.2    Lodge, P.A.3
  • 111
    • 0022971348 scopus 로고
    • Coxsackievirus B 3 myocarditis T cell autoimmunity to heart antigens is resistant to cyclosporin A treatment
    • Estrin M, Smith C, Huber SA: Coxsackievirus B-3 myocarditis. T-cell autoimmunity to heart antigens is resistant to cyclosporin-A treatment. Am. J. Pathol. 125, 244-251 (1986).
    • (1986) Am. J. Pathol. , vol.125 , pp. 244-251
    • Estrin, M.1    Smith, C.2    Huber, S.A.3
  • 112
    • 33745240931 scopus 로고    scopus 로고
    • A genome wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon induced helicase IFIH1 region
    • Smyth DJ, Cooper JD, Bailey R et al.: A genome-wide association study of nonsynonymous SNPs identifies a Type 1 diabetes locus in the interferon-induced helicase (IFIH1) region. Nat. Genet. 38, 617-619 (2006).
    • (2006) Nat. Genet. , vol.38 , pp. 617-619
    • Smyth, D.J.1    Cooper, J.D.2    Bailey, R.3
  • 113
    • 65249131713 scopus 로고    scopus 로고
    • Rare variants of IFIH1 a gene implicated in antiviral responses protect against type 1 diabetes
    • Nejentsev S, Walker N, Riches D, Egholm M, Todd JA: Rare variants of IFIH1, a gene implicated in antiviral responses, protect against Type 1 diabetes. Science 324, 387-389 (2009).
    • (2009) Science , vol.324 , pp. 387-389
    • Nejentsev, S.1    Walker, N.2    Riches, D.3    Egholm, M.4    Todd, J.A.5
  • 114
    • 67649415364 scopus 로고    scopus 로고
    • Identification of loss of function mutations in human genes encoding RIG I and MDA5: Implications for resistance to type i diabetes
    • Shigemoto T, Kageyama M, Hirai R, Zheng J, Yoneyama M, Fujita T: Identification of loss of function mutations in human genes encoding RIG-I and MDA5: implications for resistance to type I diabetes. J. Biol. Chem. 284, 13348-13354 (2009).
    • (2009) J. Biol. Chem. , vol.284 , pp. 13348-13354
    • Shigemoto, T.1    Kageyama, M.2    Hirai, R.3    Zheng, J.4    Yoneyama, M.5    Fujita, T.6
  • 115
    • 34548682991 scopus 로고    scopus 로고
    • Interferons induce an antiviral state in human pancreatic islet cells
    • Hultcrantz M, Huhn MH, Wolf M et al.: Interferons induce an antiviral state in human pancreatic islet cells. Virology 367(1), 92-101 (2007).
    • (2007) Virology , vol.367 , Issue.1 , pp. 92-101
    • Hultcrantz, M.1    Huhn, M.H.2    Wolf, M.3
  • 116
    • 38449115829 scopus 로고    scopus 로고
    • Beyond double stranded RNA type I IFN induction by 3pRNA and other viral nucleic acids
    • Schlee M, Barchet W, Hornung V, Hartmann G: Beyond double-stranded RNA-type I IFN induction by 3pRNA and other viral nucleic acids. Curr. Top. Microbiol. Immunol. 316, 207-230 (2007).
    • (2007) Curr. Top. Microbiol. Immunol , vol.316 , pp. 207-230
    • Schlee, M.1    Barchet, W.2    Hornung, V.3    Hartmann, G.4
  • 117
    • 0036349074 scopus 로고    scopus 로고
    • Regulation of the interferon inducible PKR kinase gene: The KCS element is a constitutive promoter element that functions in concert with the interferon stimulated response element
    • Ward SV, Samuel CE: Regulation of the interferon-inducible PKR kinase gene: the KCS element is a constitutive promoter element that functions in concert with the interferon-stimulated response element. Virology 296, 136-146 (2002).
    • (2002) Virology , vol.296 , pp. 136-146
    • Ward, S.V.1    Samuel, C.E.2
  • 118
    • 0026748244 scopus 로고
    • Coxsackievirus B4 infection of the mouse pancreas: The role of natural killer cells in the control of virus replication and resistance to infection
    • Vella C, Festenstein H: Coxsackievirus B4 infection of the mouse pancreas: the role of natural killer cells in the control of virus replication and resistance to infection. J. Gen. Virol. 73(Pt 6), 1379-1386 (1992).
    • (1992) J. Gen. Virol , vol.73 , pp. 1379-1386
    • Vella, C.1    Festenstein, H.2
  • 119
    • 63649114185 scopus 로고    scopus 로고
    • Cxcl10 inhibits viral replication through recruitment of natural killer cells in coxsackievirus B3 induced myocarditis
    • Yuan J, Liu Z, Lim T et al.: CXCL10 inhibits viral replication through recruitment of natural killer cells in coxsackievirus B3-induced myocarditis. Circ. Res. 104(5), 628-638 (2009).
    • (2009) Circ. Res. , vol.104 , Issue.5 , pp. 628-638
    • Yuan, J.1    Liu, Z.2    Lim, T.3
  • 120
    • 0025910160 scopus 로고
    • Expression of perforin in infiltrating cells in murine hearts with acute myocarditis caused by coxsackievirus B3
    • Seko Y, Shinkai Y, Kawasaki A et al.: Expression of perforin in infiltrating cells in murine hearts with acute myocarditis caused by coxsackievirus B3. Circulation 84, 788-795 (1991).
    • (1991) Circulation , vol.84 , pp. 788-795
    • Seko, Y.1    Shinkai, Y.2    Kawasaki, A.3
  • 121
    • 0028818233 scopus 로고
    • The role of CD8 T lymphocytes in coxsackievirus B3 induced myocarditis
    • Henke A, Huber SA, Stelzner A, Whitton JL: The role of CD8+ T lymphocytes in coxsackievirus B3-induced myocarditis. J. Virol. 69, 6720-6728 (1995).
    • (1995) J. Virol. , vol.69 , pp. 6720-6728
    • Henke, A.1    Huber, S.A.2    Stelzner, A.3    Whitton, J.L.4
  • 122
    • 0022548807 scopus 로고
    • Involvement of natural killer cells in coxsackievirus B3 induced murine myocarditis
    • Godeny EK, Gauntt CJ: Involvement of natural killer cells in coxsackievirus B3-induced murine myocarditis. J. Immunol. 137, 1695-1702 (1986).
    • (1986) J. Immunol , vol.137 , pp. 1695-1702
    • Godeny, E.K.1    Gauntt, C.J.2
  • 123
    • 0023280175 scopus 로고
    • Murine natural killer cells limit coxsackievirus B3 replication
    • Godeny EK, Gauntt CJ: Murine natural killer cells limit coxsackievirus B3 replication. J. Immunol. 139, 913-918 (1987).
    • (1987) J. Immunol , vol.139 , pp. 913-918
    • Godeny, E.K.1    Gauntt, C.J.2
  • 124
    • 33745250533 scopus 로고    scopus 로고
    • Inhibition of protein trafficking by coxsackievirus B3: Multiple viral proteins target a single organelle
    • Cornell CT, Kiosses WB, Harkins S, Whitton JL: Inhibition of protein trafficking by coxsackievirus B3: multiple viral proteins target a single organelle. J. Virol. 80, 6637-6647 (2006).
    • (2006) J. Virol. , vol.80 , pp. 6637-6647
    • Cornell, C.T.1    Kiosses, W.B.2    Harkins, S.3    Whitton, J.L.4
  • 125
    • 34250891237 scopus 로고    scopus 로고
    • Coxsackievirus B3 proteins directionally complement each other to downregulate surface MHC class I
    • Cornell CT, Kiosses WB, Harkins S, Whitton JL: Coxsackievirus B3 proteins directionally complement each other to downregulate surface MHC class I. J. Virol. 81, 6785-6797 (2007).
    • (2007) J. Virol. , vol.81 , pp. 6785-6797
    • Cornell, C.T.1    Kiosses, W.B.2    Harkins, S.3    Whitton, J.L.4
  • 127
    • 0000419304 scopus 로고
    • Agammaglobulinemia
    • Bruton OC: Agammaglobulinemia. Pediatrics 9, 722-728 (1952).
    • (1952) Pediatrics , vol.9 , pp. 722-728
    • Bruton, O.C.1
  • 128
    • 0000434534 scopus 로고
    • Disturbance in g globulin synthesis as experiments of nature
    • Good RA, Zak SJ: Disturbance in g-globulin synthesis as experiments of nature. Pediatrics 18, 109-149 (1956).
    • (1956) Pediatrics , vol.18 , pp. 109-149
    • Good, R.A.1    Zak, S.J.2
  • 129
    • 0020701013 scopus 로고
    • Specificity of IgM antibodies in acute human coxsackievirus B infections analysed by indirect solid phase enzyme immunoassay and immunoblot technique
    • Dörries R, ter Meulen V: Specificity of IgM antibodies in acute human coxsackievirus B infections, analysed by indirect solid phase enzyme immunoassay and immunoblot technique. J. Gen. Virol. 64(Pt 1), 159-167 (1983).
    • (1983) J. Gen. Virol , vol.64 , pp. 159-167
    • Dörries, R.1    Ter Meulen, V.2
  • 130
    • 0023247258 scopus 로고
    • Coxsackievirus B 3 myocarditis acute and chronic forms of the disease caused by different immunopathogenic mechanisms
    • Lodge PA, Herzum M, Olszewski J, Huber SA: Coxsackievirus B-3 myocarditis. Acute and chronic forms of the disease caused by different immunopathogenic mechanisms. Am. J. Pathol. 128, 455-463 (1987).
    • (1987) Am. J. Pathol. , vol.128 , pp. 455-463
    • Lodge, P.A.1    Herzum, M.2    Olszewski, J.3    Huber, S.A.4
  • 131
    • 64749085759 scopus 로고    scopus 로고
    • Mechanisms and results of the antibody dependent enhancement of viral infections and role in the pathogenesis of coxsackievirus B induced diseases
    • Sauter P, Hober D: Mechanisms and results of the antibody-dependent enhancement of viral infections and role in the pathogenesis of coxsackievirus B-induced diseases. Microbes Infect. 11, 443-451 (2009).
    • (2009) Microbes Infect. , vol.11 , pp. 443-451
    • Sauter, P.1    Hober, D.2
  • 132
    • 0028179348 scopus 로고
    • Identification of serotype specific and nonserotype specific B cell epitopes of coxsackie B virus using synthetic peptides
    • Haarmann CM, Schwimmbeck PL, Mertens T, Schultheiss HP, Strauer BE: Identification of serotype-specific and nonserotype-specific B-cell epitopes of coxsackie B virus using synthetic peptides. Virology 200, 381-389 (1994).
    • (1994) Virology , vol.200 , pp. 381-389
    • Haarmann, C.M.1    Schwimmbeck, P.L.2    Mertens, T.3    Schultheiss, H.P.4    Strauer, B.E.5
  • 133
    • 0033508486 scopus 로고    scopus 로고
    • Coxsackievirus B3 induced myocarditis in MHC class II deficient mice
    • Leipner C, Borchers M, Merkle I, Stelzner A: Coxsackievirus B3-induced myocarditis in MHC class II-deficient mice. J. Hum. Virol. 2, 102-114 (1999).
    • (1999) J. Hum. Virol , vol.2 , pp. 102-114
    • Leipner, C.1    Borchers, M.2    Merkle, I.3    Stelzner, A.4
  • 134
    • 0018142231 scopus 로고
    • Myocardial changes after infection with coxsackie virus B3 in nude mice
    • Hashimoto I, Komatsu T: Myocardial changes after infection with coxsackie virus B3 in nude mice. Br. J. Exp. Pathol. 59, 13-20 (1978).
    • (1978) Br. J. Exp. Pathol. , vol.59 , pp. 13-20
    • Hashimoto, I.1    Komatsu, T.2
  • 135
    • 0016299499 scopus 로고
    • Involvement of T lymphocytes in the pathogenesis of coxsackie virus B3 heart disease
    • Woodruff JF, Woodruff JJ: Involvement of T lymphocytes in the pathogenesis of coxsackie virus B3 heart disease. J. Immunol. 113, 1726-1734 (1974).
    • (1974) J. Immunol , vol.113 , pp. 1726-1734
    • Woodruff, J.F.1    Woodruff, J.J.2
  • 136
    • 0028175694 scopus 로고
    • Differential Th1 and Th2 cell responses in male and female BALB c mice infected with coxsackievirus group B type 3
    • Huber SA, Pfaeffle B: Differential Th1 and Th2 cell responses in male and female BALB/c mice infected with coxsackievirus group B type 3. J. Virol. 68, 5126-5132 (1994).
    • (1994) J. Virol. , vol.68 , pp. 5126-5132
    • Huber, S.A.1    Pfaeffle, B.2
  • 137
    • 0021040070 scopus 로고
    • Coxsackievirus B3 producing fatal meningoencephalitis in a patient with X linked agammaglobulinemia
    • Cooper JB, Pratt WR, English BK, Shearer WT: Coxsackievirus B3 producing fatal meningoencephalitis in a patient with X-linked agammaglobulinemia. Am. J. Dis. Child 137, 82-83 (1983).
    • (1983) Am. J. Dis. Child , vol.137 , pp. 82-83
    • Cooper, J.B.1    Pratt, W.R.2    English, B.K.3    Shearer, W.T.4
  • 138
    • 0024603936 scopus 로고
    • Coxsackie B3 virus encephalitis in a patient with agammaglobulinaemia
    • Hertel NT, Pedersen FK, Heilmann C: Coxsackie B3 virus encephalitis in a patient with agammaglobulinaemia. Eur. J. Pediatr. 148, 642-643 (1989).
    • (1989) Eur. J. Pediatr , vol.148 , pp. 642-643
    • Hertel, N.T.1    Pedersen, F.K.2    Heilmann, C.3
  • 140
    • 0026747966 scopus 로고
    • Chronic enteroviral meningoencephalitis in agammaglobulinemia: Case report and literature review
    • Misbah SA, Spickett GP, Ryba PC et al.: Chronic enteroviral meningoencephalitis in agammaglobulinemia: case report and literature review. J. Clin. Immunol. 12, 266-270 (1992).
    • (1992) J. Clin. Immunol , vol.12 , pp. 266-270
    • Misbah, S.A.1    Spickett, G.P.2    Ryba, P.C.3
  • 142
    • 0023848076 scopus 로고
    • Chronic group a coxsackievirus infection in agammaglobulinemia: Demonstration of genomic variation of serotypically identical isolates persistently excreted by the same patient
    • ONeil KM, Pallansch MA, Winkelstein JA, Lock TM, Modlin JF: Chronic group A coxsackievirus infection in agammaglobulinemia: demonstration of genomic variation of serotypically identical isolates persistently excreted by the same patient. J. Infect. Dis. 157, 183-186 (1988).
    • (1988) J. Infect. Dis. , vol.157 , pp. 183-186
    • O'Neil, K.M.1    Pallansch, M.A.2    Winkelstein, J.A.3    Lock, T.M.4    Modlin, J.F.5
  • 143
    • 0031688798 scopus 로고    scopus 로고
    • Prolonged replication of a type 1 vaccine derived poliovirus in an immunodeficient patient
    • Kew OM, Sutter RW, Nottay BK et al.: Prolonged replication of a type 1 vaccine-derived poliovirus in an immunodeficient patient. J. Clin. Microbiol. 36, 2893-2899 (1998).
    • (1998) J. Clin. Microbiol. , vol.36 , pp. 2893-2899
    • Kew, O.M.1    Sutter, R.W.2    Nottay, B.K.3
  • 144
    • 10044268841 scopus 로고    scopus 로고
    • Long term excretion of vaccine derived poliovirus by a healthy child
    • Martin J, Odoom K, Tuite G et al.: Long-term excretion of vaccine-derived poliovirus by a healthy child. J. Virol. 78, 13839-13847 (2004).
    • (2004) J. Virol. , vol.78 , pp. 13839-13847
    • Martin, J.1    Odoom, K.2    Tuite, G.3
  • 146
    • 34547107847 scopus 로고    scopus 로고
    • Influence of pan caspase inhibitors on coxsackievirus B3 infected CD19 B lymphocytes
    • Jarasch N, Martin U, Zell R, Wutzler P, Henke A: Influence of pan-caspase inhibitors on coxsackievirus B3-infected CD19+ B lymphocytes. Apoptosis 12, 1633-1643 (2007).
    • (2007) Apoptosis , vol.12 , pp. 1633-1643
    • Jarasch, N.1    Martin, U.2    Zell, R.3    Wutzler, P.4    Henke, A.5
  • 147
    • 0028969648 scopus 로고
    • A case of protracted coxsackie virus meningoencephalitis in a marginally immunodeficient child treated successfully with intravenous immunoglobulin
    • Geller TJ, Condie D: A case of protracted coxsackie virus meningoencephalitis in a marginally immunodeficient child treated successfully with intravenous immunoglobulin. J. Neurol. Sci. 129, 131-133 (1995).
    • (1995) J. Neurol. Sci. , vol.129 , pp. 131-133
    • Geller, T.J.1    Condie, D.2
  • 148
    • 0023173653 scopus 로고
    • Perinatal transmission of coxsackievirus B3 in mice
    • Modlin JF, Bowman M: Perinatal transmission of coxsackievirus B3 in mice. J. Infect. Dis. 156, 21-25 (1987).
    • (1987) J. Infect. Dis. , vol.156 , pp. 21-25
    • Modlin, J.F.1    Bowman, M.2
  • 150
    • 0018757630 scopus 로고
    • Lack of correlation between neutralizing antibody production and suppression of coxsackievirus B 3 replication in target organs: Evidence for involvement of mononuclear inflammatory cells in host defense
    • Woodruff JF: Lack of correlation between neutralizing antibody production and suppression of coxsackievirus B-3 replication in target organs: evidence for involvement of mononuclear inflammatory cells in host defense. J. Immunol. 123, 31-36 (1979).
    • (1979) J. Immunol , vol.123 , pp. 31-36
    • Woodruff, J.F.1
  • 151
    • 0026499963 scopus 로고
    • Enteroviral infection of mice with severe combined immunodeficiency evidence for direct viral pathogenesis of myocardial injury
    • Chow LH, Beisel KW, McManus BM: Enteroviral infection of mice with severe combined immunodeficiency. Evidence for direct viral pathogenesis of myocardial injury. Lab. Invest. 66, 24-31 (1992).
    • (1992) Lab. Invest. , vol.66 , pp. 24-31
    • Chow, L.H.1    Beisel, K.W.2    McManus, B.M.3
  • 152
    • 0028139393 scopus 로고
    • Persistence of replicating coxsackievirus B3 in the athymic murine heart is associated with development of myocarditic lesions
    • Sato S, Tsutsumi R, Burke A et al.: Persistence of replicating coxsackievirus B3 in the athymic murine heart is associated with development of myocarditic lesions. J. Gen. Virol. 75, 2911-2924 (1994).
    • (1994) J. Gen. Virol , vol.75 , pp. 2911-2924
    • Sato, S.1    Tsutsumi, R.2    Burke, A.3
  • 153
    • 0021183433 scopus 로고
    • Coxsackievirus B3 persistence and myocarditis in NFR nu nu and nu mice
    • Schnurr DP, Schmidt NJ: Coxsackievirus B3 persistence and myocarditis in NFR nu/nu and +/nu mice. Med. Microbiol. Immunol. 173, 1-7 (1984).
    • (1984) Med. Microbiol. Immunol. , vol.173 , pp. 1-7
    • Schnurr, D.P.1    Schmidt, N.J.2
  • 154
    • 0017619249 scopus 로고
    • Generation of cytotoxic t lymphocytes during coxsackievirus B 3 infection I Model and viral specificity
    • Wong CY, Woodruff JJ, Woodruff JF: Generation of cytotoxic T lymphocytes during coxsackievirus B-3 infection. I. Model and viral specificity. J. Immunol. 118, 1159-1164 (1977).
    • (1977) J. Immunol. , vol.118 , pp. 1159-1164
    • Wong, C.Y.1    Woodruff, J.J.2    Woodruff, J.F.3
  • 155
    • 0021716095 scopus 로고
    • Cardiac injury in myocarditis induced by coxsackievirus group b type 3 in Balb c mice is mediated by Lyt 2 cytolytic lymphocytes
    • Guthrie M, Lodge PA, Huber SA: Cardiac injury in myocarditis induced by coxsackievirus group B, type 3 in Balb/c mice is mediated by Lyt 2+ cytolytic lymphocytes. Cell. Immunol. 88, 558-567 (1984).
    • (1984) Cell. Immunol. , vol.88 , pp. 558-567
    • Guthrie, M.1    Lodge, P.A.2    Huber, S.A.3
  • 156
    • 0026723093 scopus 로고
    • T cells expressing the gd T cell receptor potentiate coxsackievirus B3 induced myocarditis
    • Huber SA, Moraska A, Choate M: T cells expressing the gd T-cell receptor potentiate coxsackievirus B3-induced myocarditis. J. Virol. 66, 6541-6546 (1992).
    • (1992) J. Virol. , vol.66 , pp. 6541-6546
    • Huber, S.A.1    Moraska, A.2    Choate, M.3
  • 157
    • 0033015081 scopus 로고    scopus 로고
    • T cells contribute to disease severity during coxsackievirus B4 infection
    • Ramsingh AI, Lee WT, Collins DN, Armstrong LE: T cells contribute to disease severity during coxsackievirus B4 infection. J. Virol. 73, 3080-3086 (1999).
    • (1999) J. Virol. , vol.73 , pp. 3080-3086
    • Ramsingh, A.I.1    Lee, W.T.2    Collins, D.N.3    Armstrong, L.E.4
  • 158
    • 0024316954 scopus 로고
    • Coxsackievirus induced disease CD4 cells initiate both myocarditis and pancreatitis in DBA 2 mice
    • Blay R, Simpson K, Leslie K, Huber S: Coxsackievirus-induced disease. CD4+ cells initiate both myocarditis and pancreatitis in DBA/2 mice. Am. J. Pathol. 135, 899-907 (1989).
    • (1989) Am. J. Pathol. , vol.135 , pp. 899-907
    • Blay, R.1    Simpson, K.2    Leslie, K.3    Huber, S.4
  • 159
    • 0033578663 scopus 로고    scopus 로고
    • Susceptibility to myocarditis is dependent on the response of ab T lymphocytes to coxsackieviral infection
    • Opavsky MA, Penninger J, Aitken K et al.: Susceptibility to myocarditis is dependent on the response of ab T lymphocytes to coxsackieviral infection. Circ. Res. 85, 551-558 (1999).
    • (1999) Circ. Res. , vol.85 , pp. 551-558
    • Opavsky, M.A.1    Penninger, J.2    Aitken, K.3
  • 160
    • 52649088192 scopus 로고    scopus 로고
    • Identification of HLA A 01-and HLA A02 restricted CD8 T-cell epitopes shared among group B enteroviruses
    • Weinzierl AO, Rudolf D, Maurer D et al.: Identification of HLA-A 01-and HLA-A02-restricted CD8+ T-cell epitopes shared among group B enteroviruses. J. Gen. Virol. 89, 2090-2097 (2008).
    • (2008) J. Gen. Virol , vol.89 , pp. 2090-2097
    • Weinzierl, A.O.1    Rudolf, D.2    Maurer, D.3
  • 161
    • 68449094059 scopus 로고    scopus 로고
    • Differential interferon responses enhance viral epitope generation by myocardial immunoproteasomes in murine enterovirus myocarditis
    • Jakel S, Kuckelkorn U, Szalay G et al.: Differential interferon responses enhance viral epitope generation by myocardial immunoproteasomes in murine enterovirus myocarditis. Am. J. Pathol. 175, 510-518 (2009).
    • (2009) Am. J. Pathol , vol.175 , pp. 510-518
    • Jakel, S.1    Kuckelkorn, U.2    Szalay, G.3
  • 162
    • 77953621541 scopus 로고    scopus 로고
    • Generation of in silico predicted coxsackievirus B3 derived MHC class I epitopes by proteasomes
    • Voigt A, Jakel S, Textoris-Taube K et al.: Generation of in silico predicted coxsackievirus B3-derived MHC class I epitopes by proteasomes. Amino Acids 39(1), 243-255 (2009).
    • (2009) Amino Acids , vol.39 , Issue.1 , pp. 243-255
    • Voigt, A.1    Jakel, S.2    Textoris Taube, K.3
  • 163
    • 10044238928 scopus 로고    scopus 로고
    • Identification of a naturally processed cytotoxic CD8 T cell epitope of coxsackievirus B4 presented by HLA A2.1 and located in the PEVKEK region of the P2C nonstructural protein
    • Varela-Calvino R, Skowera A, Arif S, Peakman M: Identification of a naturally processed cytotoxic CD8 T-cell epitope of coxsackievirus B4, presented by HLA-A2.1 and located in the PEVKEK region of the P2C nonstructural protein. J. Virol. 78, 13399-13408 (2004).
    • (2004) J. Virol. , vol.78 , pp. 13399-13408
    • Varela Calvino, R.1    Skowera, A.2    Arif, S.3    Peakman, M.4
  • 164
    • 0032482177 scopus 로고    scopus 로고
    • Direct visualization of antigen-specific CD8 T cells during the primary immune response to epstein barr virus in vivo
    • Callan MF, Tan L, Annels N et al.: Direct visualization of antigen-specific CD8+ T cells during the primary immune response to Epstein-Barr virus in vivo. J. Exp. Med. 187, 1395-1402 (1998).
    • (1998) J. Exp. Med. , vol.187 , pp. 1395-1402
    • Callan, M.F.1    Tan, L.2    Annels, N.3
  • 165
    • 43049154506 scopus 로고    scopus 로고
    • Human effector and memory CD8 T cell responses to smallpox and yellow fever vaccines
    • Miller JD, van der Most RG, Akondy RS et al.: Human effector and memory CD8+ T cell responses to smallpox and yellow fever vaccines. Immunity 28, 710-722 (2008).
    • (2008) Immunity , vol.28 , pp. 710-722
    • Miller, J.D.1    Van Der Most, R.G.2    Akondy, R.S.3
  • 166
    • 42449103934 scopus 로고    scopus 로고
    • Enumeration and functional evaluation of virus-specific CD4 and CD8 T cells in lymphoid and peripheral sites of coxsackievirus B3 infection
    • Kemball CC, Harkins S, Whitton JL: Enumeration and functional evaluation of virus-specific CD4+ and CD8+ T cells in lymphoid and peripheral sites of coxsackievirus B3 infection. J. Virol. 82, 4331-4342 (2008).
    • (2008) J. Virol. , vol.82 , pp. 4331-4342
    • Kemball, C.C.1    Harkins, S.2    Whitton, J.L.3
  • 167
    • 62749102116 scopus 로고    scopus 로고
    • Enhanced resistance to coxsackievirus B3 induced myocarditis by intranasal co immunization of lymphotactin gene encapsulated in chitosan particle
    • Yue Y, Xu W, Hu L, Jiang Z, Xiong S: Enhanced resistance to coxsackievirus B3-induced myocarditis by intranasal co-immunization of lymphotactin gene encapsulated in chitosan particle. Virology 386, 438-447 (2009).
    • (2009) Virology , vol.386 , pp. 438-447
    • Yue, Y.1    Xu, W.2    Hu, L.3    Jiang, Z.4    Xiong, S.5
  • 168
    • 73449110595 scopus 로고    scopus 로고
    • Coxsackievirus B3 inhibits antigen presentation in vivo exerting a profound and selective effect on the MHC class I pathway
    • Kemball CC, Harkins S, Whitmire JK, Flynn CT, Feuer R, Whitton JL: Coxsackievirus B3 inhibits antigen presentation in vivo, exerting a profound and selective effect on the MHC class I pathway. PLoS Path. 5, E1000618 (2009).
    • (2009) PLoS Path. , vol.5
    • Kemball, C.C.1    Harkins, S.2    Whitmire, J.K.3    Flynn, C.T.4    Feuer, R.5    Whitton, J.L.6
  • 169
    • 0035130057 scopus 로고    scopus 로고
    • Using recombinant coxsackievirus B3 to evaluate the induction and protective efficacy of CD8 T cells during picornavirus infection
    • Slifka MK, Pagarigan RR, Mena I, Feuer R, Whitton JL: Using recombinant coxsackievirus B3 to evaluate the induction and protective efficacy of CD8+ T cells during picornavirus infection. J. Virol. 75, 2377-2387 (2001).
    • (2001) J. Virol. , vol.75 , pp. 2377-2387
    • Slifka, M.K.1    Pagarigan, R.R.2    Mena, I.3    Feuer, R.4    Whitton, J.L.5
  • 170
    • 0034889233 scopus 로고    scopus 로고
    • Functional avidity maturation of CD8 T cells without selection of higher affinity TCR
    • Slifka MK, Whitton JL: Functional avidity maturation of CD8+ T cells without selection of higher affinity TCR. Nat. Immunol. 2, 711-717 (2001).
    • (2001) Nat. Immunol , vol.2 , pp. 711-717
    • Slifka, M.K.1    Whitton, J.L.2
  • 171
    • 67349224723 scopus 로고    scopus 로고
    • Packaging limits and stability of HIV 1 sequences in a coxsackievirus B vector
    • Miller JP, Geng Y, Ng HL, Yang OO, Krogstad P: Packaging limits and stability of HIV-1 sequences in a coxsackievirus B vector. Vaccine 27, 3992-4000 (2009).
    • (2009) Vaccine , vol.27 , pp. 3992-4000
    • Miller, J.P.1    Geng, Y.2    Ng, H.L.3    Yang, O.O.4    Krogstad, P.5
  • 172
    • 16244408648 scopus 로고    scopus 로고
    • A proline rich region in the coxsackievirus 3A protein is required for the protein to inhibit endoplasmic reticulum to golgi transport
    • Wessels E, Duijsings D, Notebaart RA, Melchers WJ, van Kuppeveld FJ: A proline-rich region in the coxsackievirus 3A protein is required for the protein to inhibit endoplasmic reticulum-to-Golgi transport. J. Virol. 79, 5163-5173 (2005).
    • (2005) J. Virol. , vol.79 , pp. 5163-5173
    • Wessels, E.1    Duijsings, D.2    Notebaart, R.A.3    Melchers, W.J.4    Van Kuppeveld, F.J.5
  • 173
    • 33744928427 scopus 로고    scopus 로고
    • The coxsackievirus 2B protein increases efflux of ions from the endoplasmic reticulum and golgi thereby inhibiting protein trafficking through the golgi
    • De Jong AS, Visch HJ, de Mattia F et al.: The coxsackievirus 2B protein increases efflux of ions from the endoplasmic reticulum and Golgi, thereby inhibiting protein trafficking through the Golgi. J. Biol. Chem. 281, 14144-14150 (2006).
    • (2006) J. Biol. Chem. , vol.281 , pp. 14144-14150
    • De Jong, A.S.1    Visch, H.J.2    De Mattia, F.3
  • 174
    • 33746476490 scopus 로고    scopus 로고
    • A viral protein that blocks Arf1-mediated COP I assembly by inhibiting the guanine nucleotide exchange factor GBF1
    • Wessels E, Duijsings D, Niu TK et al.: A viral protein that blocks Arf1-mediated COP-I assembly by inhibiting the guanine nucleotide exchange factor GBF1. Dev. Cell 11, 191-201 (2006).
    • (2006) Dev. Cell , vol.11 , pp. 191-201
    • Wessels, E.1    Duijsings, D.2    Niu, T.K.3
  • 175
    • 33751210320 scopus 로고    scopus 로고
    • Effects of picornavirus 3A proteins on protein transport and GBF1 dependent COP I recruitment
    • Wessels E, Duijsings D, Lanke KH et al.: Effects of picornavirus 3A proteins on protein transport and GBF1-dependent COP-I recruitment. J. Virol. 80, 11852-11860 (2006).
    • (2006) J. Virol. , vol.80 , pp. 11852-11860
    • Wessels, E.1    Duijsings, D.2    Lanke, K.H.3
  • 176
    • 41149092135 scopus 로고    scopus 로고
    • Functional analysis of picornavirus 2B proteins: effects on calcium homeostasis and intracellular protein trafficking
    • De Jong AS, de MF, van Dommelen MM et al.: Functional analysis of picornavirus 2B proteins: effects on calcium homeostasis and intracellular protein trafficking. J. Virol. 82, 3782-3790 (2008).
    • (2008) J. Virol. , vol.82 , pp. 3782-3790
    • De Jong, A.S.1    De, M.F.2    Van Dommelen, M.M.3
  • 177
    • 33846562974 scopus 로고    scopus 로고
    • Outside looking in: The inner workings of the cross presentation pathway within dendritic cells
    • Villadangos JA, Heath WR, Carbone FR: Outside looking in: the inner workings of the cross-presentation pathway within dendritic cells. Trends Immunol. 28, 45-47 (2007).
    • (2007) Trends Immunol , vol.28 , pp. 45-47
    • Villadangos, J.A.1    Heath, W.R.2    Carbone, F.R.3
  • 178
    • 0032493432 scopus 로고    scopus 로고
    • Poliovirus vaccine vectors elicit antigen specific cytotoxic T cells and protect mice against lethal challenge with malignant melanoma cells expressing a model antigen
    • Mandl S, Sigal LJ, Rock KL, Andino R: Poliovirus vaccine vectors elicit antigen-specific cytotoxic T cells and protect mice against lethal challenge with malignant melanoma cells expressing a model antigen. Proc. Natl Acad. Sci. USA 95, 8216-8221 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 8216-8221
    • Mandl, S.1    Sigal, L.J.2    Rock, K.L.3    Andino, R.4
  • 179
    • 0028918959 scopus 로고
    • Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A
    • Doedens JR, Kirkegaard K: Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A. EMBO J. 14, 894-907 (1995).
    • (1995) EMBO J. , vol.14 , pp. 894-907
    • Doedens, J.R.1    Kirkegaard, K.2
  • 181
    • 0034877005 scopus 로고    scopus 로고
    • Poliovirus 3A protein limits interleukin-6 IL 6 IL 8 and b interferon secretion during viral infection
    • Dodd DA, Giddings TH Jr, Kirkegaard K: Poliovirus 3A protein limits interleukin-6 (IL-6), IL-8, and b interferon secretion during viral infection. J. Virol. 75, 8158-8165 (2001).
    • (2001) J. Virol. , vol.75 , pp. 8158-8165
    • Dodd, D.A.1    Giddings Jr., T.H.2    Kirkegaard, K.3
  • 182
    • 18144371146 scopus 로고    scopus 로고
    • Virus specific CD4 and CD8 cytotoxic T cell responses and long term T cell memory in individuals vaccinated against polio
    • Wahid R, Cannon MJ, Chow M: Virus-specific CD4+ and CD8+ cytotoxic T-cell responses and long-term T-cell memory in individuals vaccinated against polio. J. Virol. 79, 5988-5995 (2005).
    • (2005) J. Virol. , vol.79 , pp. 5988-5995
    • Wahid, R.1    Cannon, M.J.2    Chow, M.3
  • 183
    • 10644270663 scopus 로고    scopus 로고
    • Dendritic cells and macrophages are productively infected by poliovirus
    • Wahid R, Cannon MJ, Chow M: Dendritic cells and macrophages are productively infected by poliovirus. J. Virol. 79, 401-409 (2005).
    • (2005) J. Virol. , vol.79 , pp. 401-409
    • Wahid, R.1    Cannon, M.J.2    Chow, M.3
  • 184
    • 0036059867 scopus 로고    scopus 로고
    • T cell epitopes in coxsackievirus B4 structural proteins concentrate in regions conserved between enteroviruses
    • Marttila J, Hyoty H, Vilja P et al.: T cell epitopes in coxsackievirus B4 structural proteins concentrate in regions conserved between enteroviruses. Virology 293, 217-224 (2002).
    • (2002) Virology , vol.293 , pp. 217-224
    • Marttila, J.1    Hyoty, H.2    Vilja, P.3
  • 186
    • 0034703817 scopus 로고    scopus 로고
    • Immunogenicity of a foreign peptide expressed within a capsid protein of an attenuated coxsackievirus
    • Halim SS, Ostrowski SE, Lee WT, Ramsingh AI: Immunogenicity of a foreign peptide expressed within a capsid protein of an attenuated coxsackievirus. Vaccine 19, 958-965 (2001).
    • (2001) Vaccine , vol.19 , pp. 958-965
    • Halim, S.S.1    Ostrowski, S.E.2    Lee, W.T.3    Ramsingh, A.I.4
  • 187
    • 67650999438 scopus 로고    scopus 로고
    • Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in mice
    • Filippi CM, Estes EA, Oldham JE, von Herrath MG: Immunoregulatory mechanisms triggered by viral infections protect from Type 1 diabetes in mice. J. Clin. Invest. 119, 1515-1523 (2009).
    • (2009) J. Clin. Invest. , vol.119 , pp. 1515-1523
    • Filippi, C.M.1    Estes, E.A.2    Oldham, J.E.3    Von Herrath, M.G.4
  • 188
    • 76949091325 scopus 로고    scopus 로고
    • In vivo requirement for Atg5 in antigen presentation by dendritic cells
    • Lee HK, Mattei LM, Steinberg BE et al.: In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity 32, 227-239 (2010).
    • (2010) Immunity , vol.32 , pp. 227-239
    • Lee, H.K.1    Mattei, L.M.2    Steinberg, B.E.3
  • 189
    • 0034667875 scopus 로고    scopus 로고
    • Vg1 T cells suppress and Vg4 T cells promote susceptibility to coxsackievirus B3 induced myocarditis in mice
    • Huber SA, Graveline D, Newell MK, Born WK, OBrien RL: Vg1+ T cells suppress and Vg4+ T cells promote susceptibility to coxsackievirus B3-induced myocarditis in mice. J. Immunol. 165, 4174-4181 (2000).
    • (2000) J. Immunol , vol.165 , pp. 4174-4181
    • Huber, S.A.1    Graveline, D.2    Newell, M.K.3    Born, W.K.4    O'Brien, R.L.5
  • 190
    • 0034743641 scopus 로고    scopus 로고
    • Cytokine production by Vg T cell subsets is an important factor determining CD4 Th cell phenotype and susceptibility of BALB c mice to coxsackievirus B3 induced myocarditis
    • Huber SA, Graveline D, Born WK, OBrien RL: Cytokine production by Vg+-T-cell subsets is an important factor determining CD4+ -Th-cell phenotype and susceptibility of BALB/c mice to coxsackievirus B3-induced myocarditis. J. Virol. 75, 5860-5869 (2001).
    • (2001) J. Virol. , vol.75 , pp. 5860-5869
    • Huber, S.A.1    Graveline, D.2    Born, W.K.3    O'Brien, R.L.4
  • 191
    • 29844450044 scopus 로고    scopus 로고
    • T cells expressing the Vg1 T cell receptor enhance virus neutralizing antibody response during coxsackievirus B3 infection of BALB c mice: Differences in male and female mice
    • Huber S, Sartini D: T cells expressing the Vg1 T-cell receptor enhance virus-neutralizing antibody response during coxsackievirus B3 infection of BALB/c mice: differences in male and female mice. Viral Immunol. 18, 730-739 (2005).
    • (2005) Viral Immunol , vol.18 , pp. 730-739
    • Huber, S.1    Sartini, D.2
  • 192
    • 33746495734 scopus 로고    scopus 로고
    • CD1d expression on hemopoietic cells promotes CD4 Th1 response in coxsackievirus B3 induced myocarditis
    • Huber SA: CD1d expression on hemopoietic cells promotes CD4+ Th1 response in coxsackievirus B3 induced myocarditis. Virology 352, 226-236 (2006).
    • (2006) Virology , vol.352 , pp. 226-236
    • Huber, S.A.1
  • 193
    • 0033372642 scopus 로고    scopus 로고
    • Apoptosis in coxsackievirus B3 induced myocarditis and dilated cardiomyopathy
    • Huber SA, Budd RC, Rossner K, Newell MK: Apoptosis in coxsackievirus B3-induced myocarditis and dilated cardiomyopathy. Ann. NY Acad. Sci. 887, 181-190 (1999).
    • (1999) Ann. NY Acad. Sci. , vol.887 , pp. 181-190
    • Huber, S.A.1    Budd, R.C.2    Rossner, K.3    Newell, M.K.4
  • 194
    • 0035984016 scopus 로고    scopus 로고
    • Gd T cells promote a Th1 response during coxsackievirus B3 infection in vivo: Role of fas and fas ligand
    • Huber SA, Shi C, Budd RC: gd T cells promote a Th1 response during coxsackievirus B3 infection in vivo: role of Fas and Fas ligand. J. Virol. 76, 6487-6494 (2002).
    • (2002) J. Virol. , vol.76 , pp. 6487-6494
    • Huber, S.A.1    Shi, C.2    Budd, R.C.3
  • 195
    • 67650499571 scopus 로고    scopus 로고
    • Depletion of gd T cells increases CD4 foxp3 T regulatory cell response in coxsackievirus B3 induced myocarditis
    • Huber SA: Depletion of gd+ T cells increases CD4+ FoxP3 (T regulatory) cell response in coxsackievirus B3-induced myocarditis. Immunology 127, 567-576 (2009).
    • (2009) Immunology , vol.127 , pp. 567-576
    • Huber, S.A.1
  • 196
    • 0026644152 scopus 로고
    • Synergistic interaction of interferon b and interferon g in coxsackievirus B3 infected carrier cultures of human myocardial fibroblasts
    • Heim A, Canu A, Kirschner P et al.: Synergistic interaction of interferon-b and interferon-g in coxsackievirus B3-infected carrier cultures of human myocardial fibroblasts. J. Infect. Dis. 166, 958-965 (1992).
    • (1992) J. Infect. Dis. , vol.166 , pp. 958-965
    • Heim, A.1    Canu, A.2    Kirschner, P.3
  • 197
    • 0022401092 scopus 로고
    • Coxsackie B3 virus can replicate in cultured human foetal heart cells and is inhibited by interferon
    • Kandolf R, Canu A, Hofschneider PH: Coxsackie B3 virus can replicate in cultured human foetal heart cells and is inhibited by interferon. J. Mol. Cell Cardiol. 17, 167-181 (1985).
    • (1985) J. Mol. Cell Cardiol. , vol.17 , pp. 167-181
    • Kandolf, R.1    Canu, A.2    Hofschneider, P.H.3
  • 198
    • 0012146742 scopus 로고
    • Persistent infections by coxsackie virus B3 In
    • Auti F (Ed.), Raven Press, NY, USA
    • Yiyun C, Yagi S, Schnurr D: Persistent infections by coxsackie virus B3. In: Pathogenesis and control of viral infections. Auti F (Ed.), Raven Press, NY, USA, 105-112, (1989).
    • (1989) Pathogenesis and control of viral infections , pp. 105-112
    • Yiyun, C.1    Yagi, S.2    Schnurr, D.3
  • 200
    • 0025747521 scopus 로고
    • Viral persistence during the developmental phase of coxsackievirus B1 induced murine polymyositis
    • Tam PE, Schmidt AM, Ytterberg SR, Messner RP: Viral persistence during the developmental phase of coxsackievirus B1-induced murine polymyositis. J. Virol. 65, 6654-6660 (1991).
    • (1991) J. Virol. , vol.65 , pp. 6654-6660
    • Tam, P.E.1    Schmidt, A.M.2    Ytterberg, S.R.3    Messner, R.P.4
  • 201
    • 0028385737 scopus 로고
    • Duration of virus persistence and its relationship to inflammation in the chronic phase of coxsackievirus B1 induced murine polymyositis
    • Tam PE, Schmidt AM, Ytterberg SR, Messner RP: Duration of virus persistence and its relationship to inflammation in the chronic phase of coxsackievirus B1-induced murine polymyositis. J. Lab. Clin. Med. 123, 346-356 (1994).
    • (1994) J. Lab. Clin. Med. , vol.123 , pp. 346-356
    • Tam, P.E.1    Schmidt, A.M.2    Ytterberg, S.R.3    Messner, R.P.4
  • 202
    • 0032737032 scopus 로고    scopus 로고
    • Molecular mechanisms of coxsackievirus persistence in chronic inflammatory myopathy: Viral RNA persists through formation of a double stranded complex without associated genomic mutations or evolution
    • Tam PE, Messner RP: Molecular mechanisms of coxsackievirus persistence in chronic inflammatory myopathy: viral RNA persists through formation of a double-stranded complex without associated genomic mutations or evolution. J. Virol. 73, 10113-10121 (1999).
    • (1999) J. Virol. , vol.73 , pp. 10113-10121
    • Tam, P.E.1    Messner, R.P.2
  • 203
    • 0026565599 scopus 로고
    • Ongoing enterovirus induced myocarditis is associated with persistent heart muscle infection: Quantitative analysis of virus replication tissue damage and inflammation
    • Klingel K, Hohenadl C, Canu A et al.: Ongoing enterovirus-induced myocarditis is associated with persistent heart muscle infection: quantitative analysis of virus replication, tissue damage, and inflammation. Proc. Natl Acad. Sci. USA 89, 314-318 (1992).
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 314-318
    • Klingel, K.1    Hohenadl, C.2    Canu, A.3
  • 204
    • 0029926533 scopus 로고    scopus 로고
    • Pathogenesis of murine enterovirus myocarditis: Virus dissemination and immune cell targets
    • Klingel K, Stephan S, Sauter M et al.: Pathogenesis of murine enterovirus myocarditis: virus dissemination and immune cell targets. J. Virol. 70, 8888-8895 (1996).
    • (1996) J. Virol. , vol.70 , pp. 8888-8895
    • Klingel, K.1    Stephan, S.2    Sauter, M.3
  • 205
    • 0032483055 scopus 로고    scopus 로고
    • Low level expression of a mutant coxsackieviral cDNA induces a myocytopathic effect in culture: An approach to the study of enteroviral persistence in cardiac myocytes
    • Wessely R, Henke A, Zell R, Kandolf R, Knowlton KU: Low-level expression of a mutant coxsackieviral cDNA induces a myocytopathic effect in culture: an approach to the study of enteroviral persistence in cardiac myocytes. Circulation 98, 450-457 (1998).
    • (1998) Circulation , vol.98 , pp. 450-457
    • Wessely, R.1    Henke, A.2    Zell, R.3    Kandolf, R.4    Knowlton, K.U.5
  • 206
    • 0032189260 scopus 로고    scopus 로고
    • Transgenic expression of replicationn restricted enteroviral genomes in heart muscle induces defective excitation contraction coupling and dilated cardiomyopathy
    • Wessely R, Klingel K, Santana LF et al.: Transgenic expression of replication-restricted enteroviral genomes in heart muscle induces defective excitation-contraction coupling and dilated cardiomyopathy. J. Clin. Invest. 102, 1444-1453 (1998).
    • (1998) J. Clin. Invest , vol.102 , pp. 1444-1453
    • Wessely, R.1    Klingel, K.2    Santana, L.F.3
  • 207
    • 18744377196 scopus 로고    scopus 로고
    • 5 terminal deletions occur in coxsackievirus B3 during replication in murine hearts and cardiac myocyte cultures and correlate with encapsidation of negative strand viral RNA
    • Kim KS, Tracy S, Tapprich W et al.: 5-terminal deletions occur in coxsackievirus B3 during replication in murine hearts and cardiac myocyte cultures and correlate with encapsidation of negative-strand viral RNA. J. Virol. 79, 7024-7041 (2005).
    • (2005) J. Virol. , vol.79 , pp. 7024-7041
    • Kim, K.S.1    Tracy, S.2    Tapprich, W.3
  • 208
    • 43349098414 scopus 로고    scopus 로고
    • 5 terminal deletions in the genome of a coxsackievirus B2 strain occurred naturally in human heart
    • Chapman NM, Kim KS, Drescher KM, Oka K, Tracy S: 5 terminal deletions in the genome of a coxsackievirus B2 strain occurred naturally in human heart. Virology 375, 480-491 (2008).
    • (2008) Virology , vol.375 , pp. 480-491
    • Chapman, N.M.1    Kim, K.S.2    Drescher, K.M.3    Oka, K.4    Tracy, S.5
  • 209
    • 38849105566 scopus 로고    scopus 로고
    • Replication of coxsackievirus B3 in primary cell cultures generates novel viral genome deletions
    • Kim KS, Chapman NM, Tracy S: Replication of coxsackievirus B3 in primary cell cultures generates novel viral genome deletions. J. Virol. 82, 2033-2037 (2008).
    • (2008) J. Virol. , vol.82 , pp. 2033-2037
    • Kim, K.S.1    Chapman, N.M.2    Tracy, S.3


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