메뉴 건너뛰기




Volumn 67, Issue 5, 1996, Pages 1982-1991

Colocalization of glucagon-like peptide-1 (GLP-1) receptors, glucose transporter GLUT-2, and glucokinase mRNAs in rat hypothalamic cells: Evidence for a role of GLP-1 receptor agonists as an inhibitory signal for food and water intake

Author keywords

Brain; Food intake; Glucagon like peptide 1 receptor; Glucokinase; GLUT 2; Rat

Indexed keywords

GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 [7-36] AMIDE; GLUCOKINASE; GLUCOSE TRANSPORTER; MESSENGER RNA;

EID: 10244241840     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.67051982.x     Document Type: Article
Times cited : (204)

References (48)
  • 1
    • 0028135499 scopus 로고
    • Galanin-containing neurons in the paraventricular nucleus: A neurochemical marker for fat ingestion and body weight gain
    • Akabayashi A., Koenig J. I., Watanabe Y., Alexander J. T., and Leibowitz S. F. (1994) Galanin-containing neurons in the paraventricular nucleus: a neurochemical marker for fat ingestion and body weight gain. Proc. Natl. Acad. Sci. USA 91, 10375-10379.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10375-10379
    • Akabayashi, A.1    Koenig, J.I.2    Watanabe, Y.3    Alexander, J.T.4    Leibowitz, S.F.5
  • 2
    • 0030056878 scopus 로고    scopus 로고
    • Expression of the glucagon-like peptide-1 receptor gene in rat brain
    • Alvarez E., Roncero I., Chowen J. A., Thorens B., and Blázquez E. (1996) Expression of the glucagon-like peptide-1 receptor gene in rat brain. J. Neurochem. 66, 920-927.
    • (1996) J. Neurochem. , vol.66 , pp. 920-927
    • Alvarez, E.1    Roncero, I.2    Chowen, J.A.3    Thorens, B.4    Blázquez, E.5
  • 3
    • 0028042205 scopus 로고
    • Changes in arterial blood pressure and heart rate induced by glucagon-like peptide-1 (7-36) amide in rats
    • Barragán J. M., Rodríguez R. E., and Blázquez E. (1994) Changes in arterial blood pressure and heart rate induced by glucagon-like peptide-1 (7-36) amide in rats. Am. J. Physiol. 266, E459-E466.
    • (1994) Am. J. Physiol. , vol.266
    • Barragán, J.M.1    Rodríguez, R.E.2    Blázquez, E.3
  • 4
    • 0027197580 scopus 로고
    • Galanin in the hypothalamus of fed and fasted lean and obese Zucker rats
    • Beck B., Burlet A., Nicolas J.-P., and Burlet C. (1992) Galanin in the hypothalamus of fed and fasted lean and obese Zucker rats. Brain Res. 623, 124-130.
    • (1992) Brain Res. , vol.623 , pp. 124-130
    • Beck, B.1    Burlet, A.2    Nicolas, J.-P.3    Burlet, C.4
  • 5
    • 0026542355 scopus 로고
    • Peptides affect the intake of specific nutrients and the sympathetic nervous system
    • Bray G. A. (1992) Peptides affect the intake of specific nutrients and the sympathetic nervous system. Am. J. Clin. Nutr. 55(Suppl.), 265S-271S.
    • (1992) Am. J. Clin. Nutr. , vol.55 , Issue.SUPPL.
    • Bray, G.A.1
  • 6
    • 0028814666 scopus 로고
    • Structural characterization by affinity cross-linking of glucagon-like peptide-1 (7-36) amide receptor in rat brain
    • Calvo J. C., Yusta B., Mora F., and Blázquez E. (1995a) Structural characterization by affinity cross-linking of glucagon-like peptide-1 (7-36) amide receptor in rat brain. J. Neurochem. 64, 299-306.
    • (1995) J. Neurochem. , vol.64 , pp. 299-306
    • Calvo, J.C.1    Yusta, B.2    Mora, F.3    Blázquez, E.4
  • 7
    • 0029155996 scopus 로고
    • Glucagon-like peptide-1 (7-36) amide induces the release of aspartic acid and glutamine by the ventromedial hypothalamus of the conscious rat
    • Calvo J. C., Gisolfi C. V., Blázquez E., and Mora F. (1995b) Glucagon-like peptide-1 (7-36) amide induces the release of aspartic acid and glutamine by the ventromedial hypothalamus of the conscious rat. Brain Res. Bull. 38, 435-439.
    • (1995) Brain Res. Bull. , vol.38 , pp. 435-439
    • Calvo, J.C.1    Gisolfi, C.V.2    Blázquez, E.3    Mora, F.4
  • 8
    • 0027142421 scopus 로고
    • Differential effects of the neonatal and adult sex steroid environments on the organization and activation of hypothalamic growth hormone-releasing hormone and somatostatin neurons
    • Chowen J. A., Argente J., González-Parra S., and Garcia Segura L. M. (1993) Differential effects of the neonatal and adult sex steroid environments on the organization and activation of hypothalamic growth hormone-releasing hormone and somatostatin neurons. Endocrinology 133, 2792-2802.
    • (1993) Endocrinology , vol.133 , pp. 2792-2802
    • Chowen, J.A.1    Argente, J.2    González-Parra, S.3    Garcia Segura, L.M.4
  • 11
    • 0026648961 scopus 로고
    • Isolation and characterization of exendin-4 and exendin-3 analogue from Heloderma suspectum venom
    • Eng J., Kleinman W. A., Singh L., and Ranfman J. P. (1992) Isolation and characterization of exendin-4 and exendin-3 analogue from Heloderma suspectum venom. J. Biol. Chem. 267, 7402-7405.
    • (1992) J. Biol. Chem. , vol.267 , pp. 7402-7405
    • Eng, J.1    Kleinman, W.A.2    Singh, L.3    Ranfman, J.P.4
  • 12
    • 0026568825 scopus 로고
    • Glucagon-like peptide-I (7-36) amide (7-37): A new incretin hormone
    • Fehmann H. C., Göke R., and Göke B. (1992) Glucagon-like peptide-I (7-36) amide (7-37): a new incretin hormone. Mol. Cell. Endocrinol. 85, 39-44.
    • (1992) Mol. Cell. Endocrinol. , vol.85 , pp. 39-44
    • Fehmann, H.C.1    Göke, R.2    Göke, B.3
  • 13
    • 0021892852 scopus 로고
    • Current concepts: V. Effect of bombesin on feeding behavior
    • Gibbs J. (1985) Current concepts: V. Effect of bombesin on feeding behavior. Life Sci. 37, 147-153.
    • (1985) Life Sci. , vol.37 , pp. 147-153
    • Gibbs, J.1
  • 14
    • 0024600552 scopus 로고
    • Characterization of the receptor for glucagon-like peptide-1 (7-36) amide on plasma membranes from rat insulinoma-derived cells by covalent cross-linking
    • Göke R., Cole T., and Conlon J. M. (1989) Characterization of the receptor for glucagon-like peptide-1 (7-36) amide on plasma membranes from rat insulinoma-derived cells by covalent cross-linking. J. Mol. Endocrinol. 2, 93-98.
    • (1989) J. Mol. Endocrinol. , vol.2 , pp. 93-98
    • Göke, R.1    Cole, T.2    Conlon, J.M.3
  • 15
    • 0027184119 scopus 로고
    • Exendin-4 is a high potency agonist and truncated exendin (9-39) amide an antagonist at the glucagon-like peptide-1 (7-36) amide receptor on insulin secretin β-cells
    • Göke R., Fehmann H. C., Linn T., Schmidt H., Krause M., Eng J., and Göke B. (1993) Exendin-4 is a high potency agonist and truncated exendin (9-39) amide an antagonist at the glucagon-like peptide-1 (7-36) amide receptor on insulin secretin β-cells. J. Biol. Chem. 268, 19650-19655.
    • (1993) J. Biol. Chem. , vol.268 , pp. 19650-19655
    • Göke, R.1    Fehmann, H.C.2    Linn, T.3    Schmidt, H.4    Krause, M.5    Eng, J.6    Göke, B.7
  • 16
    • 0028867442 scopus 로고
    • Distribution of GLP-1 binding sites in the rat brain: Evidence that exendin-4 is a ligand of brain GLP-1 binding sites
    • Göke R., Larsen P. J., Mikkelsen J. D., and Sheikh S. P. (1995) Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites. Eur. J. Neurosci. 7, 2294-2300.
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 2294-2300
    • Göke, R.1    Larsen, P.J.2    Mikkelsen, J.D.3    Sheikh, S.P.4
  • 17
    • 0025161423 scopus 로고
    • Alternative splicing of glucokinase mRNA in rat liver
    • Hayzer D. J. and Iynedjian P. B. (1990) Alternative splicing of glucokinase mRNA in rat liver. Biochem. J. 270, 261-263.
    • (1990) Biochem. J. , vol.270 , pp. 261-263
    • Hayzer, D.J.1    Iynedjian, P.B.2
  • 18
    • 0021691124 scopus 로고
    • Human glucagon-like peptides 1 and 2 activate rat brain adenylate cyclase
    • Hoosein N. M. and Gurd R. S. (1984) Human glucagon-like peptides 1 and 2 activate rat brain adenylate cyclase. FEBS Lett. 178, 83-86.
    • (1984) FEBS Lett. , vol.178 , pp. 83-86
    • Hoosein, N.M.1    Gurd, R.S.2
  • 19
    • 0028101926 scopus 로고
    • Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut
    • Jetton T. L., Liang Y., Petteher C. C., Zimmerman E. C., Cox F. G., Harvath K., Metschinsky F. M., and Magnuson M. A. (1994) Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut. J. Biol. Chem. 269, 3641-3654.
    • (1994) J. Biol. Chem. , vol.269 , pp. 3641-3654
    • Jetton, T.L.1    Liang, Y.2    Petteher, C.C.3    Zimmerman, E.C.4    Cox, F.G.5    Harvath, K.6    Metschinsky, F.M.7    Magnuson, M.A.8
  • 20
    • 0027422340 scopus 로고
    • Neuropeptide Y projection from arcuate nucleus to parvocellular division of paraventricular nucleus: Specific relation to the ingestion of carbohydrate
    • Jhanwar-Uniyal M., Beck B., Jhanwar Y. S., Burlet C., and Leibowitz S. F. (1993) Neuropeptide Y projection from arcuate nucleus to parvocellular division of paraventricular nucleus: specific relation to the ingestion of carbohydrate. Brain Res. 631, 97-106.
    • (1993) Brain Res. , vol.631 , pp. 97-106
    • Jhanwar-Uniyal, M.1    Beck, B.2    Jhanwar, Y.S.3    Burlet, C.4    Leibowitz, S.F.5
  • 21
    • 0023950336 scopus 로고
    • Distribution of glucagon-like peptide I (GLP-1), glucagon, and glicentin in the rat brain: An immunocytochemical study
    • Jin S. L. C., Han V. K. M., Simmons J. G., Towle A. C., Lauder J. M., and Lund P. K. (1988) Distribution of glucagon-like peptide I (GLP-1), glucagon, and glicentin in the rat brain: an immunocytochemical study. J. Comp. Neurol, 271, 519-532.
    • (1988) J. Comp. Neurol , vol.271 , pp. 519-532
    • Jin, S.L.C.1    Han, V.K.M.2    Simmons, J.G.3    Towle, A.C.4    Lauder, J.M.5    Lund, P.K.6
  • 22
    • 0024253412 scopus 로고
    • Identification and characterization of glucagon-like peptide-1 (7-36) amide-binding sites in the rat brain and lung
    • Kanse S. M., Kreymann B., Ghatei M. A., and Bloom S. R. (1988) Identification and characterization of glucagon-like peptide-1 (7-36) amide-binding sites in the rat brain and lung. FEBS Lett. 241, 209-212.
    • (1988) FEBS Lett. , vol.241 , pp. 209-212
    • Kanse, S.M.1    Kreymann, B.2    Ghatei, M.A.3    Bloom, S.R.4
  • 25
    • 0025086236 scopus 로고
    • Stimulation of feeding by galanin: Anatomical localization and behavioral specificity of this peptide's effect in the brain
    • Kyrkouli S. E., Stanley B. G., Sirafi R. D., and Leibowitz S. F. (1990) Stimulation of feeding by galanin: anatomical localization and behavioral specificity of this peptide's effect in the brain. Peptides 11, 995-1001.
    • (1990) Peptides , vol.11 , pp. 995-1001
    • Kyrkouli, S.E.1    Stanley, B.G.2    Sirafi, R.D.3    Leibowitz, S.F.4
  • 26
    • 0026460277 scopus 로고
    • Neurochemical-neuroendocrine systems in the brain controlling macronutrient intake and metabolism
    • Leibowitz S. F. (1992) Neurochemical-neuroendocrine systems in the brain controlling macronutrient intake and metabolism. Trends Neurosci. 15, 491-497.
    • (1992) Trends Neurosci. , vol.15 , pp. 491-497
    • Leibowitz, S.F.1
  • 28
    • 0021361338 scopus 로고
    • The subfornical organ and the integration of multiple factors in thirst
    • Lind R. W., Thurnhorst R. L., and Johnson A. K. (1984) The subfornical organ and the integration of multiple factors in thirst. Physiol. Behav. 32, 69-74.
    • (1984) Physiol. Behav. , vol.32 , pp. 69-74
    • Lind, R.W.1    Thurnhorst, R.L.2    Johnson, A.K.3
  • 30
    • 0022515976 scopus 로고
    • Distribution of galanin-like immunoreactivity in the rat central nervous system
    • Melander T., Hökfelt T., and Rokaeus A. (1987) Distribution of galanin-like immunoreactivity in the rat central nervous system. J. Comp. Neurol. 248, 475-517.
    • (1987) J. Comp. Neurol. , vol.248 , pp. 475-517
    • Melander, T.1    Hökfelt, T.2    Rokaeus, A.3
  • 31
    • 0023008693 scopus 로고
    • Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing
    • Mojsov S., Heinrich G., Wilson I. B., Ravazzola M., Orci L., and Habener J. F. (1986) Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing. J. Biol. Chem. 261, 11880-11889.
    • (1986) J. Biol. Chem. , vol.261 , pp. 11880-11889
    • Mojsov, S.1    Heinrich, G.2    Wilson, I.B.3    Ravazzola, M.4    Orci, L.5    Habener, J.F.6
  • 32
    • 0026793903 scopus 로고
    • Selective release of glutamine and glutamic acid produced by perfusion of GLP-1 (7-36) amide in the basal ganglia of the conscious rat
    • Mora F., Exposito I., Sanz B., and Blázquez E. (1992) Selective release of glutamine and glutamic acid produced by perfusion of GLP-1 (7-36) amide in the basal ganglia of the conscious rat. Brain Res. Bull. 29, 359-361.
    • (1992) Brain Res. Bull. , vol.29 , pp. 359-361
    • Mora, F.1    Exposito, I.2    Sanz, B.3    Blázquez, E.4
  • 34
    • 0016191102 scopus 로고
    • Glucose inhibition of the glucose sensitive neuron in the rat lateral hypothalamus
    • Oomura Y, Ooyama H., Sugimori M., Nakamura T., and Yamada Y. (1974) Glucose inhibition of the glucose sensitive neuron in the rat lateral hypothalamus. Nature 247, 284-286.
    • (1974) Nature , vol.247 , pp. 284-286
    • Oomura, Y.1    Ooyama, H.2    Sugimori, M.3    Nakamura, T.4    Yamada, Y.5
  • 36
    • 0026024546 scopus 로고
    • Characterization of glucagon-like peptide I (7-36) amide receptors of rat lung membranes by covalent cross-linking
    • Richter G., Göke G., Göke B., Schmidt H., and Arnold R. (1991) Characterization of glucagon-like peptide I (7-36) amide receptors of rat lung membranes by covalent cross-linking. FEBS Lett. 280, 247-250.
    • (1991) FEBS Lett. , vol.280 , pp. 247-250
    • Richter, G.1    Göke, G.2    Göke, B.3    Schmidt, H.4    Arnold, R.5
  • 37
    • 0025817571 scopus 로고
    • Neuropeptide Y and food intake in fasted rats: Effects of naloxone and site of action
    • Schick R. R., Schusdziarra V., Nussbaumer C., and Classen M. (1991) Neuropeptide Y and food intake in fasted rats: effects of naloxone and site of action. Brain Res. 552, 232-239.
    • (1991) Brain Res. , vol.552 , pp. 232-239
    • Schick, R.R.1    Schusdziarra, V.2    Nussbaumer, C.3    Classen, M.4
  • 38
    • 0024338802 scopus 로고
    • GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in human
    • Schjoldager B. T. G., Mortensen P. E., Christiansen J., Orskov C., and Holst J. J. (1989) GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in human. Dig. Dis. Sci. 34, 703-708.
    • (1989) Dig. Dis. Sci. , vol.34 , pp. 703-708
    • Schjoldager, B.T.G.1    Mortensen, P.E.2    Christiansen, J.3    Orskov, C.4    Holst, J.J.5
  • 39
    • 0027499477 scopus 로고
    • Injection of anti-neuropeptide Y γ-globulin into the hypothalamic paraventricular nucleus decreases food intake in rats
    • Shibasaki T., Oda T., Imaki T., Ling N., and Demura H. (1993) Injection of anti-neuropeptide Y γ-globulin into the hypothalamic paraventricular nucleus decreases food intake in rats. Brain Res. 601, 313-316.
    • (1993) Brain Res. , vol.601 , pp. 313-316
    • Shibasaki, T.1    Oda, T.2    Imaki, T.3    Ling, N.4    Demura, H.5
  • 40
    • 0027445758 scopus 로고
    • Glucagon injected in the lateral hypothalamus stimulates sympathetic activity and suppresses monoamine metabolism
    • Shimizu H., Egawa M., Yoshimatsu H., and Bray G. (1993) Glucagon injected in the lateral hypothalamus stimulates sympathetic activity and suppresses monoamine metabolism. Brain Res. 630, 95-100.
    • (1993) Brain Res. , vol.630 , pp. 95-100
    • Shimizu, H.1    Egawa, M.2    Yoshimatsu, H.3    Bray, G.4
  • 41
    • 0026775150 scopus 로고
    • Expression cloning of the pancreatic β cell receptor for the glucoincretin hormone glucagon-like peptide-1
    • Thorens B. (1992) Expression cloning of the pancreatic β cell receptor for the glucoincretin hormone glucagon-like peptide-1. Proc. Natl. Acad. Sci. USA 89, 8641-8645.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 8641-8645
    • Thorens, B.1
  • 42
    • 0023692118 scopus 로고
    • Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney and beta-pancreatic islet cell
    • Thorens B., Sarkar H. K., Kaback H. R., and Lodish H. F. (1988) Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney and beta-pancreatic islet cell. Cell 55, 281-290.
    • (1988) Cell , vol.55 , pp. 281-290
    • Thorens, B.1    Sarkar, H.K.2    Kaback, H.R.3    Lodish, H.F.4
  • 44
    • 0025246652 scopus 로고
    • Characterization of high-affinity receptors for truncated glucagon-like peptide-1 in rat gastric glands
    • Uttenthal L. O. and Blázquez E. (1990) Characterization of high-affinity receptors for truncated glucagon-like peptide-1 in rat gastric glands. FEBS Lett. 262, 139-141.
    • (1990) FEBS Lett. , vol.262 , pp. 139-141
    • Uttenthal, L.O.1    Blázquez, E.2
  • 45
    • 0026521197 scopus 로고
    • Autoradiographic localization of receptors for glucagon-like peptide-1 (7-36) amide in rat brain
    • Uttenthal L. O., Toledano A., and Blázquez E. (1992) Autoradiographic localization of receptors for glucagon-like peptide-1 (7-36) amide in rat brain. Neuropeptides 21, 143-146.
    • (1992) Neuropeptides , vol.21 , pp. 143-146
    • Uttenthal, L.O.1    Toledano, A.2    Blázquez, E.3
  • 46
    • 0027397282 scopus 로고
    • Presence and characterization of glucagon-like peptide-1 (7-36) amide receptors in solubilized membranes of rat adipose tissue
    • Valverde I., Mérida E., Delgado E., Trapote M. A., and Villanueva-Penacarrillo M. L. (1993) Presence and characterization of glucagon-like peptide-1 (7-36) amide receptors in solubilized membranes of rat adipose tissue. Endocrinology 132, 75-79.
    • (1993) Endocrinology , vol.132 , pp. 75-79
    • Valverde, I.1    Mérida, E.2    Delgado, E.3    Trapote, M.A.4    Villanueva-Penacarrillo, M.L.5
  • 47
    • 0028900758 scopus 로고
    • Tissue-specific expression of the human receptor for glucagon-like peptide-1: Brain, heart and pancreatic forms have the same deduced amino acid sequences
    • Wei Y. and Mojsov S. (1995) Tissue-specific expression of the human receptor for glucagon-like peptide-1: brain, heart and pancreatic forms have the same deduced amino acid sequences. FEBS Lett. 358, 219-224.
    • (1995) FEBS Lett. , vol.358 , pp. 219-224
    • Wei, Y.1    Mojsov, S.2
  • 48
    • 0002894341 scopus 로고
    • Dopamine autoreceptors
    • (Creese I. and Frazer C. M., eds), Alan R. Liss, New York
    • Wolf M. E. and Roth R. M. (1987) Dopamine autoreceptors, in Dopamine Receptors (Creese I. and Frazer C. M., eds), pp. 41-62. Alan R. Liss, New York.
    • (1987) Dopamine Receptors , pp. 41-62
    • Wolf, M.E.1    Roth, R.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.