-
1
-
-
53549133638
-
The Creb1 coactivator Crtc1 is required for energy balance and fertility
-
Altarejos JY, Goebel N, Conkright MD, Inoue H, Xie J, Arias CM, Sawchenko PE, Montminy M (2008) The Creb1 coactivator Crtc1 is required for energy balance and fertility. Nat Med 14: 1112-1117
-
(2008)
Nat Med
, vol.14
, pp. 1112-1117
-
-
Altarejos, J.Y.1
Goebel, N.2
Conkright, M.D.3
Inoue, H.4
Xie, J.5
Arias, C.M.6
Sawchenko, P.E.7
Montminy, M.8
-
2
-
-
10344262616
-
Activation of cAMP response element-mediated gene expression by regulated nuclear transport of TORC proteins
-
Bittinger MA et al (2004) Activation of cAMP response element-mediated gene expression by regulated nuclear transport of TORC proteins. Curr Biol 14: 2156-2161
-
(2004)
Curr Biol
, vol.14
, pp. 2156-2161
-
-
Bittinger, M.A.1
-
3
-
-
0025038674
-
Altered expression of hypothalamic neuropeptide mRNAs in food-restricted and food-deprived rats
-
Brady LS, Smith MA, Gold PW, Herkenham M (1990) Altered expression of hypothalamic neuropeptide mRNAs in food-restricted and food-deprived rats. Neuroendocrinology 52: 441-447
-
(1990)
Neuroendocrinology
, vol.52
, pp. 441-447
-
-
Brady, L.S.1
Smith, M.A.2
Gold, P.W.3
Herkenham, M.4
-
4
-
-
33645055091
-
Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling
-
Canettieri G, Koo SH, Berdeaux R, Heredia J, Hedrick S, Zhang X, Montminy M (2005) Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling. Cell Metab 2: 331-338
-
(2005)
Cell Metab
, vol.2
, pp. 331-338
-
-
Canettieri, G.1
Koo, S.H.2
Berdeaux, R.3
Heredia, J.4
Hedrick, S.5
Zhang, X.6
Montminy, M.7
-
5
-
-
0037421635
-
Efficient large-scale production and concentration of HIV-1-based lentiviral vectors for use in vivo
-
Coleman JE, Huentelman MJ, Kasparov S, Metcalfe BL, Paton JF, Katovich MJ, Semple-Rowland SL, Raizada MK (2003) Efficient large-scale production and concentration of HIV-1-based lentiviral vectors for use in vivo. Physiol Genomics 12: 221-228
-
(2003)
Physiol Genomics
, vol.12
, pp. 221-228
-
-
Coleman, J.E.1
Huentelman, M.J.2
Kasparov, S.3
Metcalfe, B.L.4
Paton, J.F.5
Katovich, M.J.6
Semple-Rowland, S.L.7
Raizada, M.K.8
-
6
-
-
0141922981
-
TORCs: Transducers of regulated CREB activity
-
Conkright MD, Canettieri G, Screaton R, Guzman E, Miraglia L, Hogenesch JB, Montminy M (2003) TORCs: Transducers of regulated CREB activity. Mol Cell 12: 413-423
-
(2003)
Mol Cell
, vol.12
, pp. 413-423
-
-
Conkright, M.D.1
Canettieri, G.2
Screaton, R.3
Guzman, E.4
Miraglia, L.5
Hogenesch, J.B.6
Montminy, M.7
-
7
-
-
33744514139
-
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome
-
Cool B et al (2006) Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome. Cell Metab 3: 403-416
-
(2006)
Cell Metab
, vol.3
, pp. 403-416
-
-
Cool, B.1
-
8
-
-
1642453553
-
Distinct roles for insulin and insulin-like growth factor-1 receptors in pancreatic beta-cell glucose sensing revealed by RNA silencing
-
Da Silva Xavier G, Qian Q, Cullen PJ, Rutter GA (2004) Distinct roles for insulin and insulin-like growth factor-1 receptors in pancreatic beta-cell glucose sensing revealed by RNA silencing. Biochem J 377: 149-158
-
(2004)
Biochem J
, vol.377
, pp. 149-158
-
-
Da Silva Xavier, G.1
Qian, Q.2
Cullen, P.J.3
Rutter, G.A.4
-
9
-
-
34548831102
-
Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2
-
Dentin R, Liu Y, Koo SH, Hedrick S, Vargas T, Heredia J, Yates J III, Montminy M (2007) Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2. Nature 449: 366-369
-
(2007)
Nature
, vol.449
, pp. 366-369
-
-
Dentin, R.1
Liu, Y.2
Koo, S.H.3
Hedrick, S.4
Vargas, T.5
Heredia, J.6
Yates III, J.7
Montminy, M.8
-
10
-
-
0142091390
-
Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells
-
Iourgenko V et al (2003) Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells. Proc Natl Acad Sci USA 100: 12147-12152
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 12147-12152
-
-
Iourgenko, V.1
-
11
-
-
0029922595
-
Major role of 3′,5′-cyclic adenosine monophosphate-dependent protein kinase A pathway in corticotropin-releasing factor gene expression in the rat hypothalamus in vivo
-
Itoi K, Horiba N, Tozawa F, Sakai Y, Sakai K, Abe K, Demura H, Suda T (1996) Major role of 3′,5′-cyclic adenosine monophosphate-dependent protein kinase A pathway in corticotropin-releasing factor gene expression in the rat hypothalamus in vivo. Endocrinology 137 2389-2396
-
(1996)
Endocrinology
, vol.137
, pp. 2389-2396
-
-
Itoi, K.1
Horiba, N.2
Tozawa, F.3
Sakai, Y.4
Sakai, K.5
Abe, K.6
Demura, H.7
Suda, T.8
-
12
-
-
48249109104
-
Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2
-
Jansson D, Ng AC, Fu A, Depatie C, Al Azzabi M, Screaton RA (2008) Glucose controls CREB activity in islet cells via regulated phosphorylation of TORC2. Proc Natl Acad Sci USA 105: 10161-10166
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 10161-10166
-
-
Jansson, D.1
Ng, A.C.2
Fu, A.3
Depatie, C.4
Al Azzabi, M.5
Screaton, R.A.6
-
13
-
-
27144506185
-
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
-
Koo SH et al (2005) The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature 437: 1109-1111
-
(2005)
Nature
, vol.437
, pp. 1109-1111
-
-
Koo, S.H.1
-
14
-
-
9644260562
-
Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus
-
Kubota N et al (2004) Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus. J Clin Invest 114: 917-927
-
(2004)
J Clin Invest
, vol.114
, pp. 917-927
-
-
Kubota, N.1
-
15
-
-
9644260563
-
Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes
-
Lin X, Taguchi A, Park S, Kushner JA, Li F, Li Y, White MF (2004) Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes. J Clin Invest 114: 908-916
-
(2004)
J Clin Invest
, vol.114
, pp. 908-916
-
-
Lin, X.1
Taguchi, A.2
Park, S.3
Kushner, J.A.4
Li, F.5
Li, Y.6
White, M.F.7
-
16
-
-
0041624549
-
Transgenic mice expressing green fluorescent protein under the control of the melanocortin-4 receptor promoter
-
Liu H, Kishi T, Roseberry AG, Cai X, Lee CE, Montez JM, Friedman JM, Elmquist JK (2003) Transgenic mice expressing green fluorescent protein under the control of the melanocortin-4 receptor promoter. J Neurosci 23: 7143-7154
-
(2003)
J Neurosci
, vol.23
, pp. 7143-7154
-
-
Liu, H.1
Kishi, T.2
Roseberry, A.G.3
Cai, X.4
Lee, C.E.5
Montez, J.M.6
Friedman, J.M.7
Elmquist, J.K.8
-
17
-
-
33750996986
-
GAL4-NF-kappaB fusion protein augments transgene expression from neuronal promoters in the rat brain
-
Liu BH, Yang Y, Paton JF, Li F, Boulaire J, Kasparov S, Wang S (2006) GAL4-NF-kappaB fusion protein augments transgene expression from neuronal promoters in the rat brain. Mol Ther 14: 872-882
-
(2006)
Mol Ther
, vol.14
, pp. 872-882
-
-
Liu, B.H.1
Yang, Y.2
Paton, J.F.3
Li, F.4
Boulaire, J.5
Kasparov, S.6
Wang, S.7
-
18
-
-
1842484296
-
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
-
Minokoshi Y et al (2004) AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature 428: 569-574
-
(2004)
Nature
, vol.428
, pp. 569-574
-
-
Minokoshi, Y.1
-
19
-
-
33845945261
-
Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity
-
Mountjoy PD, Bailey SJ, Rutter GA (2007) Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity. Diabetologia 50: 168-177
-
(2007)
Diabetologia
, vol.50
, pp. 168-177
-
-
Mountjoy, P.D.1
Bailey, S.J.2
Rutter, G.A.3
-
20
-
-
33749859790
-
-
Identification of nesfatin-1 as a satiety molecule in the hypothalamus
-
Oh IS et al (2006) Identification of nesfatin-1 as a satiety molecule in the hypothalamus. Nature 443: 709-712
-
(2006)
Nature
, vol.443
, pp. 709-712
-
-
Oh, I.S.1
-
21
-
-
34548604499
-
Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity
-
Parton LE et al (2007) Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity. Nature 449: 228-232
-
(2007)
Nature
, vol.449
, pp. 228-232
-
-
Parton, L.E.1
-
22
-
-
36348978499
-
Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family
-
Sanders MJ, Ali ZS, Hegarty BD, Heath R, Snowden MA, Carling D (2007) Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family. J Biol Chem 282: 32539-32548
-
(2007)
J Biol Chem
, vol.282
, pp. 32539-32548
-
-
Sanders, M.J.1
Ali, Z.S.2
Hegarty, B.D.3
Heath, R.4
Snowden, M.A.5
Carling, D.6
-
23
-
-
5344228270
-
The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector
-
Screaton RA et al (2004) The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector. Cell 119: 61-74
-
(2004)
Cell
, vol.119
, pp. 61-74
-
-
Screaton, R.A.1
-
24
-
-
0028101988
-
Extracellular glucose concentration in mammalian brain: Continuous monitoring of changes during increased neuronal activity and upon limitation in oxygen supply in normo-, hypo-, and hyperglycemic animals
-
Silver IA, Erecinska M (1994) Extracellular glucose concentration in mammalian brain: Continuous monitoring of changes during increased neuronal activity and upon limitation in oxygen supply in normo-, hypo-, and hyperglycemic animals. J Neurosci 14: 5068-5076
-
(1994)
J Neurosci
, vol.14
, pp. 5068-5076
-
-
Silver, I.A.1
Erecinska, M.2
|