Exploring the roles of CD8+ T lymphocytes in the pathogenesis of autoimmune demyelination

Seminars in Immunopathology

Volumn 32, Issue 2, 2010, Pages 197-209

  Johnson, Trina A ^a   Jirik, Frank R ^b   Fournier, Sylvie ^c  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

CD4+ T lymphocyte; CD8+ T lymphocyte; Central nervous system; Cytotoxic T lymphocyte; Demyelination; Experimental autoimmune encephalomyelitis; Multiple sclerosis; Myelin basic protein; Myelin oligodendrocyte glycoprotein; Oligodendrocyte; Transgenic mice

Indexed keywords

CD28 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; HLA ANTIGEN; HLA ANTIGEN CLASS 1; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR BETA; MYELIN PROTEIN;

ALLERGIC ENCEPHALOMYELITIS; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL SPECIFICITY; CYTOTOXICITY; DEMYELINATING DISEASE; DEMYELINATION; DISEASE PREDISPOSITION; GENETIC PREDISPOSITION; HUMAN; IMMUNE DEFICIENCY; IMMUNOLOGICAL TOLERANCE; IMMUNOPATHOGENESIS; IMMUNOREGULATION; IMMUNOSTIMULATION; LYMPHOCYTE FUNCTION; MEMORY T LYMPHOCYTE; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INFLAMMATION; NERVOUS SYSTEM INJURY; NONHUMAN; PRIORITY JOURNAL; REVIEW; T CELL DEPLETION; TH1 CELL; ANIMAL; DISEASE MODEL; IMMUNOLOGY; MOUSE; PATHOLOGY;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; DEMYELINATING AUTOIMMUNE DISEASES, CNS; DEMYELINATING DISEASES; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; HUMANS; MICE; MULTIPLE SCLEROSIS;

EID: 77955486302     PISSN: 18632297     EISSN: 18632300     Source Type: Journal    
DOI: 10.1007/s00281-010-0199-7     Document Type: Review

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