Pathogenic MOG-reactive CD8+ T cells require MOG-reactive CD4+ T cells for sustained CNS inflammation during chronic EAE

Journal of Neuroimmunology

Volumn 213, Issue 1-2, 2009, Pages 60-68

  Bettini, Maria ^a   Rosenthal, Kristen ^b   Evavold, Brian D ^b  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Central nervous system; Experimental autoimmune encephalomyelitis; Myelin oligodendrocyte protein; T cell

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; EPITOPE; GAMMA INTERFERON; INTERLEUKIN 2; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL INFILTRATION; CELL TRANSPORT; CONTROLLED STUDY; DISEASE MODEL; DISEASE SEVERITY; FEMALE; IMMUNOPATHOGENESIS; MICROGLIA; MOUSE; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; SCORING SYSTEM;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; CHEMOTAXIS, LEUKOCYTE; DISEASE MODELS, ANIMAL; ENCEPHALITIS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GLIOSIS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; MOLECULAR WEIGHT; MYELIN-ASSOCIATED GLYCOPROTEIN; PEPTIDE FRAGMENTS;

EID: 68049088662     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2009.05.017     Document Type: Article

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