-
1
-
-
0030837555
-
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
-
Myers MP, Stolarov JP, Eng C, Li J, Wang SI, Wigler MH, Parsons R, Tonks NK: P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc Natl Acad Sci USA 1997, 94:9052-9057
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 9052-9057
-
-
Myers, M.P.1
Stolarov, J.P.2
Eng, C.3
Li, J.4
Wang, S.I.5
Wigler, M.H.6
Parsons, R.7
Tonks, N.K.8
-
2
-
-
33644513730
-
Beyond PTEN mutations: The PI3K pathway as an integrator of multiple inputs during tumorigenesis
-
Cully M, You H, Levine AJ, Mak TW: Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis. Nat Rev Cancer 2006, 6:184-192
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 184-192
-
-
Cully, M.1
You, H.2
Levine, A.J.3
Mak, T.W.4
-
3
-
-
17144436629
-
Identification of a candidate tumour suppressor gene. MMAC1, at chromosome 10q233 that is mutated in multiple advanced cancers
-
Steck PA, Pershouse MA, Jasser SA, Yung WK, Lin H, Ligon AH, Langford LA, Baumgard ML, Hattier T, Davis T, Frye C, Hu R, Swedlund B, Teng DH, Tavtigian SV: Identification of a candidate tumour suppressor gene. MMAC1, at chromosome 10q233 that is mutated in multiple advanced cancers. Nat Genet 1997, 15:356-362
-
(1997)
Nat Genet
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
Yung, W.K.4
Lin, H.5
Ligon, A.H.6
Langford, L.A.7
Baumgard, M.L.8
Hattier, T.9
Davis, T.10
Frye, C.11
Hu, R.12
Swedlund, B.13
Teng, D.H.14
Tavtigian, S.V.15
-
4
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw D, Marsh DJ, Li J, Dahia PL, Wang SI, Zheng Z, Bose S, Call KM, Tsou HC, Peacocke M, Eng C, Parsons R: Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet 1997, 16:64-67
-
(1997)
Nat Genet
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
Dahia, P.L.4
Wang, S.I.5
Zheng, Z.6
Bose, S.7
Call, K.M.8
Tsou, H.C.9
Peacocke, M.10
Eng, C.11
Parsons, R.12
-
5
-
-
0031870959
-
Pten is essential for embryonic development and tumour suppression
-
Di Cristofano A, Pesce B, Cordon-Cardo C, Pandolfi PP: Pten is essential for embryonic development and tumour suppression. Nat Genet 1998, 19:348-355
-
(1998)
Nat Genet
, vol.19
, pp. 348-355
-
-
Di Cristofano, A.1
Pesce, B.2
Cordon-Cardo, C.3
Pandolfi, P.P.4
-
6
-
-
0034234268
-
High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice
-
Stambolic V, Tsao MS, Macpherson D, Suzuki A, Chapman WB, Mak TW: High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice. Cancer Res 2000, 60:3605-3611
-
(2000)
Cancer Res
, vol.60
, pp. 3605-3611
-
-
Stambolic, V.1
Tsao, M.S.2
Macpherson, D.3
Suzuki, A.4
Chapman, W.B.5
Mak, T.W.6
-
7
-
-
13044250465
-
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
-
Podsypanina K, Ellenson LH, Nemes A, Gu J, Tamura M, Yamada KM, Cordon-Cardo C, Catoretti G, Fisher PE, Parsons R: Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems. Proc Natl Acad Sci USA 1999, 96:1563-1568
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1563-1568
-
-
Podsypanina, K.1
Ellenson, L.H.2
Nemes, A.3
Gu, J.4
Tamura, M.5
Yamada, K.M.6
Cordon-Cardo, C.7
Catoretti, G.8
Fisher, P.E.9
Parsons, R.10
-
8
-
-
13144249184
-
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
-
Suzuki A, de la Pompa JL, Stambolic V, Elia AJ, Sasaki T, del Barco Barrantes I, Ho A, Wakeham A, Itie A, Khoo W, Fukumoto M, Mak TW: High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice. Curr Biol 1998, 8:1169-1178
-
(1998)
Curr Biol
, vol.8
, pp. 1169-1178
-
-
Suzuki, A.1
de la Pompa, J.L.2
Stambolic, V.3
Elia, A.J.4
Sasaki, T.5
del Barco Barrantes, I.6
Ho, A.7
Wakeham, A.8
Itie, A.9
Khoo, W.10
Fukumoto, M.11
Mak, T.W.12
-
9
-
-
0032843540
-
Impaired Fas response and autoimmunity in Pten+/- mice
-
Di Cristofano A, Kotsi P, Peng YF, Cordon-Cardo C, Elkon KB, Pandolfi PP: Impaired Fas response and autoimmunity in Pten+/- mice. Science 1999, 285:2122-2125
-
(1999)
Science
, vol.285
, pp. 2122-2125
-
-
Di Cristofano, A.1
Kotsi, P.2
Peng, Y.F.3
Cordon-Cardo, C.4
Elkon, K.B.5
Pandolfi, P.P.6
-
10
-
-
0035734381
-
Pten regulates neuronal soma size: A mouse model of Lhermitte-Duclos disease
-
Kwon CH, Zhu X, Zhang J, Knoop LL, Tharp R, Smeyne RJ, Eberhart CG, Burger PC, Baker SJ: Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease. Nat Genet 2001, 29:404-411
-
(2001)
Nat Genet
, vol.29
, pp. 404-411
-
-
Kwon, C.H.1
Zhu, X.2
Zhang, J.3
Knoop, L.L.4
Tharp, R.5
Smeyne, R.J.6
Eberhart, C.G.7
Burger, P.C.8
Baker, S.J.9
-
11
-
-
33644499133
-
Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner
-
Yoo LI, Liu DW, Le Vu S, Bronson RT, Wu H, Yuan J: Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner. Cancer Res 2006, 66:1929-1939
-
(2006)
Cancer Res
, vol.66
, pp. 1929-1939
-
-
Yoo, L.I.1
Liu, D.W.2
Le Vu, S.3
Bronson, R.T.4
Wu, H.5
Yuan, J.6
-
12
-
-
0034995242
-
T cell-specific loss of Pten leads to defects in central and peripheral tolerance
-
Suzuki A, Yamaguchi MT, Ohteki T, Sasaki T, Kaisho T, Kimura Y, Yoshida R, Wakeham A, Higuchi T, Fukumoto M, Tsubata T, Ohashi PS, Koyasu S, Penninger JM, Nakano T, Mak TW: T cell-specific loss of Pten leads to defects in central and peripheral tolerance. Immunity 2001, 14:523-534
-
(2001)
Immunity
, vol.14
, pp. 523-534
-
-
Suzuki, A.1
Yamaguchi, M.T.2
Ohteki, T.3
Sasaki, T.4
Kaisho, T.5
Kimura, Y.6
Yoshida, R.7
Wakeham, A.8
Higuchi, T.9
Fukumoto, M.10
Tsubata, T.11
Ohashi, P.S.12
Koyasu, S.13
Penninger, J.M.14
Nakano, T.15
Mak, T.W.16
-
13
-
-
5444269438
-
The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and pre-TCR-mediated signaling
-
Hagenbeek TJ, Naspetti M, Malergue F, Garcon F, Nunes JA, Cleutjens KB, Trapman J, Krimpenfort P, Spits H: The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and pre-TCR-mediated signaling. J Exp Med 2004, 200:883-894
-
(2004)
J Exp Med
, vol.200
, pp. 883-894
-
-
Hagenbeek, T.J.1
Naspetti, M.2
Malergue, F.3
Garcon, F.4
Nunes, J.A.5
Cleutjens, K.B.6
Trapman, J.7
Krimpenfort, P.8
Spits, H.9
-
14
-
-
33748335576
-
PTEN inhibits IL-2 receptor-mediated expansion of CD4+ CD25+ Tregs
-
Walsh PT, Buckler JL, Zhang J, Gelman AE, Dalton NM, Taylor DK, Bensinger SJ, Hancock WW, Turka LA: PTEN inhibits IL-2 receptor-mediated expansion of CD4+ CD25+ Tregs. J Clin Invest 2006, 116:2521-2531
-
(2006)
J Clin Invest
, vol.116
, pp. 2521-2531
-
-
Walsh, P.T.1
Buckler, J.L.2
Zhang, J.3
Gelman, A.E.4
Dalton, N.M.5
Taylor, D.K.6
Bensinger, S.J.7
Hancock, W.W.8
Turka, L.A.9
-
15
-
-
33749132566
-
Cutting edge: T-cell requirement for CD28 costimulation is due to negative regulation of TCR signals by PTEN
-
Buckler JL, Walsh PT, Porrett PM, Choi Y, Turka LA: Cutting edge: T-cell requirement for CD28 costimulation is due to negative regulation of TCR signals by PTEN. J Immunol 2006, 177:4262-4266
-
(2006)
J Immunol
, vol.177
, pp. 4262-4266
-
-
Buckler, J.L.1
Walsh, P.T.2
Porrett, P.M.3
Choi, Y.4
Turka, L.A.5
-
17
-
-
1342345214
-
The CD4-Th1 model for multiple sclerosis: A critical (correction of crucial) re-appraisal
-
Lassmann H, Ransohoff RM: The CD4-Th1 model for multiple sclerosis: a critical (correction of crucial) re-appraisal. Trends Immunol 2004, 25:132-137
-
(2004)
Trends Immunol
, vol.25
, pp. 132-137
-
-
Lassmann, H.1
Ransohoff, R.M.2
-
18
-
-
0020676803
-
Multiple sclerosis: Distribution of T cell subsets within active chronic lesions
-
Traugott U, Reinherz EL, Raine CS: Multiple sclerosis: distribution of T cell subsets within active chronic lesions. Science 1983, 219: 308-310
-
(1983)
Science
, vol.219
, pp. 308-310
-
-
Traugott, U.1
Reinherz, E.L.2
Raine, C.S.3
-
19
-
-
0022459287
-
Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions
-
Hauser SL, Bhan AK, Gilles F, Kemp M, Kerr C, Weiner HL: Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions. Ann Neurol 1986, 19:578-587
-
(1986)
Ann Neurol
, vol.19
, pp. 578-587
-
-
Hauser, S.L.1
Bhan, A.K.2
Gilles, F.3
Kemp, M.4
Kerr, C.5
Weiner, H.L.6
-
20
-
-
0034618094
-
Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction
-
Babbe H, Roers A, Waisman A, Lassmann H, Goebels N, Hohlfeld R, Friese M, Schroder R, Deckert M, Schmidt S, Ravid R, Rajewsky K: Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction. J Exp Med 2000, 192:393-404
-
(2000)
J Exp Med
, vol.192
, pp. 393-404
-
-
Babbe, H.1
Roers, A.2
Waisman, A.3
Lassmann, H.4
Goebels, N.5
Hohlfeld, R.6
Friese, M.7
Schroder, R.8
Deckert, M.9
Schmidt, S.10
Ravid, R.11
Rajewsky, K.12
-
21
-
-
0035801332
-
A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis
-
Huseby ES, Liggitt D, Brabb T, Schnabel B, Ohlen C, Goverman J: A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis. J Exp Med 2001, 194:669-676
-
(2001)
J Exp Med
, vol.194
, pp. 669-676
-
-
Huseby, E.S.1
Liggitt, D.2
Brabb, T.3
Schnabel, B.4
Ohlen, C.5
Goverman, J.6
-
22
-
-
0035932949
-
CD8+ T cells control the TH phenotype of MBP-reactive CD4+ T cells in EAE mice
-
Jiang H, Braunstein NS, Yu B, Winchester R, Chess L: CD8+ T cells control the TH phenotype of MBP-reactive CD4+ T cells in EAE mice. Proc Natl Acad Sci USA 2001, 98:6301-6306
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6301-6306
-
-
Jiang, H.1
Braunstein, N.S.2
Yu, B.3
Winchester, R.4
Chess, L.5
-
23
-
-
85047690427
-
Regulatory functions of CD8+CD28- T cells in an autoimmune disease model
-
Najafian N, Chitnis T, Salama AD, Zhu B, Benou C, Yuan X, Clarkson MR, Sayegh MH, Khoury SJ: Regulatory functions of CD8+CD28- T cells in an autoimmune disease model. J Clin Invest 2003, 112:1037-1048
-
(2003)
J Clin Invest
, vol.112
, pp. 1037-1048
-
-
Najafian, N.1
Chitnis, T.2
Salama, A.D.3
Zhu, B.4
Benou, C.5
Yuan, X.6
Clarkson, M.R.7
Sayegh, M.H.8
Khoury, S.J.9
-
24
-
-
0035877190
-
Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice
-
Sun D, Whitaker JN, Huang Z, Liu D, Coleclough C, Wekerle H, Raine CS: Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice. J Immunol 2001, 166:7579-7587
-
(2001)
J Immunol
, vol.166
, pp. 7579-7587
-
-
Sun, D.1
Whitaker, J.N.2
Huang, Z.3
Liu, D.4
Coleclough, C.5
Wekerle, H.6
Raine, C.S.7
-
25
-
-
34249021086
-
Experimental autoimmune encephalomyelitis mediated by CD8+ T cells
-
Ji Q, Goverman J: Experimental autoimmune encephalomyelitis mediated by CD8+ T cells. Ann NY Acad Sci 2007, 1103:157-166
-
(2007)
Ann NY Acad Sci
, vol.1103
, pp. 157-166
-
-
Ji, Q.1
Goverman, J.2
-
26
-
-
0033542458
-
Modelling T-cell memory by genetic marking of memory T cells in vivo
-
Jacob J, Baltimore D: Modelling T-cell memory by genetic marking of memory T cells in vivo. Nature 1999, 399:593-597
-
(1999)
Nature
, vol.399
, pp. 593-597
-
-
Jacob, J.1
Baltimore, D.2
-
27
-
-
0041427990
-
A transgenic mouse model genetically tags all activated CD8 T cells
-
Maris CH, Miller JD, Altman JD, Jacob J: A transgenic mouse model genetically tags all activated CD8 T cells. J Immunol 2003, 171:2393-2401
-
(2003)
J Immunol
, vol.171
, pp. 2393-2401
-
-
Maris, C.H.1
Miller, J.D.2
Altman, J.D.3
Jacob, J.4
-
28
-
-
34948850396
-
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice
-
Yanagi S, Kishimoto H, Kawahara K, Sasaki T, Sasaki M, Nishio M, Yajima N, Hamada K, Horie Y, Kubo H, Whitsett JA, Mak TW, Nakano T, Nakazato M, Suzuki A: Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice. J Clin Invest 2007, 117:2929-2940
-
(2007)
J Clin Invest
, vol.117
, pp. 2929-2940
-
-
Yanagi, S.1
Kishimoto, H.2
Kawahara, K.3
Sasaki, T.4
Sasaki, M.5
Nishio, M.6
Yajima, N.7
Hamada, K.8
Horie, Y.9
Kubo, H.10
Whitsett, J.A.11
Mak, T.W.12
Nakano, T.13
Nakazato, M.14
Suzuki, A.15
-
29
-
-
34147139532
-
The Pten/PI3K pathway governs the homeostasis of Valpha14iNKT cells
-
Kishimoto H, Ohteki T, Yajima N, Kawahara K, Natsui M, Kawarasaki S, Hamada K, Horie Y, Kubo Y, Arase S, Taniguchi M, Vanhaesebroeck B, Mak TW, Nakano T, Koyasu S, Sasaki T, Suzuki A: The Pten/PI3K pathway governs the homeostasis of Valpha14iNKT cells. Blood 2007, 109:3316-3324
-
(2007)
Blood
, vol.109
, pp. 3316-3324
-
-
Kishimoto, H.1
Ohteki, T.2
Yajima, N.3
Kawahara, K.4
Natsui, M.5
Kawarasaki, S.6
Hamada, K.7
Horie, Y.8
Kubo, Y.9
Arase, S.10
Taniguchi, M.11
Vanhaesebroeck, B.12
Mak, T.W.13
Nakano, T.14
Koyasu, S.15
Sasaki, T.16
Suzuki, A.17
-
30
-
-
3042856262
-
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
-
Srinivas S, Watanabe T, Lin CS, William CM, Tanabe Y, Jessell TM, Costantini F: Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol 2001, 1:4-11
-
(2001)
BMC Dev Biol
, vol.1
, pp. 4-11
-
-
Srinivas, S.1
Watanabe, T.2
Lin, C.S.3
William, C.M.4
Tanabe, Y.5
Jessell, T.M.6
Costantini, F.7
-
31
-
-
1242336753
-
A1 adenosine receptor upregulation and activation attenuates neuroinflammation and demyelination in a model of multiple sclerosis
-
Tsutsui S, Schnermann J, Noorbakhsh F, Henry S, Yong VW, Winston BW, Warren K, Power C: A1 adenosine receptor upregulation and activation attenuates neuroinflammation and demyelination in a model of multiple sclerosis. J Neurosci 2004, 24:1521-1529
-
(2004)
J Neurosci
, vol.24
, pp. 1521-1529
-
-
Tsutsui, S.1
Schnermann, J.2
Noorbakhsh, F.3
Henry, S.4
Yong, V.W.5
Winston, B.W.6
Warren, K.7
Power, C.8
-
32
-
-
26444447974
-
An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization
-
Weaver A, Goncalves da Silva A, Nuttall RK, Edwards DR, Shapiro SD, Rivest S, Yong VW: An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization. FASEB J 2005, 19:1668-1670
-
(2005)
FASEB J
, vol.19
, pp. 1668-1670
-
-
Weaver, A.1
Goncalves da Silva, A.2
Nuttall, R.K.3
Edwards, D.R.4
Shapiro, S.D.5
Rivest, S.6
Yong, V.W.7
-
33
-
-
0031916192
-
TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination
-
Liu J, Marino MW, Wong G, Grail D, Dunn A, Bettadapura J, Slavin AJ, Old L, Bernard CC: TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination. Nat Med 1998, 4:78-83
-
(1998)
Nat Med
, vol.4
, pp. 78-83
-
-
Liu, J.1
Marino, M.W.2
Wong, G.3
Grail, D.4
Dunn, A.5
Bettadapura, J.6
Slavin, A.J.7
Old, L.8
Bernard, C.C.9
-
34
-
-
0036260089
-
Targeting leukocyte MMPs and transmigration: Minocycline as a potential therapy for multiple sclerosis
-
Brundula V, Rewcastle NB, Metz LM, Bernard CC, Yong VW: Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis. Brain 2002, 125:1297-1308
-
(2002)
Brain
, vol.125
, pp. 1297-1308
-
-
Brundula, V.1
Rewcastle, N.B.2
Metz, L.M.3
Bernard, C.C.4
Yong, V.W.5
-
35
-
-
18944397611
-
Selective expression of the Cre recombinase in late-stage thymocytes using the distal promoter of the Lck gene
-
Zhang DJ, Wang Q, Wei J, Baimukanova G, Buchholz F, Stewart AF, Mao X, Killeen N: Selective expression of the Cre recombinase in late-stage thymocytes using the distal promoter of the Lck gene. J Immunol 2005, 174:6725-6731
-
(2005)
J Immunol
, vol.174
, pp. 6725-6731
-
-
Zhang, D.J.1
Wang, Q.2
Wei, J.3
Baimukanova, G.4
Buchholz, F.5
Stewart, A.F.6
Mao, X.7
Killeen, N.8
-
36
-
-
0026764280
-
Tissue- and site-specific DNA recombination in transgenic mice
-
Orban PC, Chui D, Marth JD: Tissue- and site-specific DNA recombination in transgenic mice. Proc Natl Acad Sci USA 1992, 89:6861-6865
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 6861-6865
-
-
Orban, P.C.1
Chui, D.2
Marth, J.D.3
-
37
-
-
18244365863
-
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival
-
Lee PP, Fitzpatrick DR, Beard C, Jessup HK, Lehar S, Makar KW, Perez-Melgosa M, Sweetser MT, Schlissel MS, Nguyen S, Cherry SR, Tsai JH, Tucker SM, Weaver WM, Kelso A, Jaenisch R, Wilson CB: A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity 2001, 15:763-774
-
(2001)
Immunity
, vol.15
, pp. 763-774
-
-
Lee, P.P.1
Fitzpatrick, D.R.2
Beard, C.3
Jessup, H.K.4
Lehar, S.5
Makar, K.W.6
Perez-Melgosa, M.7
Sweetser, M.T.8
Schlissel, M.S.9
Nguyen, S.10
Cherry, S.R.11
Tsai, J.H.12
Tucker, S.M.13
Weaver, W.M.14
Kelso, A.15
Jaenisch, R.16
Wilson, C.B.17
-
38
-
-
0842346270
-
Do phosphoinositide 3-kinases direct lymphocyte navigation?
-
Ward SG: Do phosphoinositide 3-kinases direct lymphocyte navigation? Trends Immunol 2004, 25:67-74
-
(2004)
Trends Immunol
, vol.25
, pp. 67-74
-
-
Ward, S.G.1
-
39
-
-
14344259226
-
Leukocytes on the move with phosphoinositide 3-kinase and its downstream effectors
-
Procko E, McColl SR: Leukocytes on the move with phosphoinositide 3-kinase and its downstream effectors. Bioessays 2005, 27:153-163
-
(2005)
Bioessays
, vol.27
, pp. 153-163
-
-
Procko, E.1
McColl, S.R.2
-
40
-
-
0035835824
-
PTEN: Life as a tumor suppressor
-
Simpson L, Parsons R: PTEN: life as a tumor suppressor. Exp Cell Res 2001, 264:29-41
-
(2001)
Exp Cell Res
, vol.264
, pp. 29-41
-
-
Simpson, L.1
Parsons, R.2
-
41
-
-
0035263289
-
p27Kip1 is required for PTEN-induced G1 growth arrest
-
Gottschalk AR, Basila D, Wong M, Dean NM, Brandts CH, Stokoe D, Haas-Kogan DA: p27Kip1 is required for PTEN-induced G1 growth arrest. Cancer Res 2001, 61:2105-2111
-
(2001)
Cancer Res
, vol.61
, pp. 2105-2111
-
-
Gottschalk, A.R.1
Basila, D.2
Wong, M.3
Dean, N.M.4
Brandts, C.H.5
Stokoe, D.6
Haas-Kogan, D.A.7
-
42
-
-
15844384256
-
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice
-
Fero ML, Rivkin M, Tasch M, Porter P, Carow CE, Firpo E, Polyak K, Tsai LH, Broudy V, Perlmutter RM, Kaushansky K, Roberts JM: A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice. Cell 1996, 85:733-744
-
(1996)
Cell
, vol.85
, pp. 733-744
-
-
Fero, M.L.1
Rivkin, M.2
Tasch, M.3
Porter, P.4
Carow, C.E.5
Firpo, E.6
Polyak, K.7
Tsai, L.H.8
Broudy, V.9
Perlmutter, R.M.10
Kaushansky, K.11
Roberts, J.M.12
-
43
-
-
15844415946
-
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1)
-
Kiyokawa H, Kineman RD, Manova-Todorova KO, Soares VC, Hoffman ES, Ono M, Khanam D, Hayday AC, Frohman LA, Koff A: Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). Cell 1996, 85:721-732
-
(1996)
Cell
, vol.85
, pp. 721-732
-
-
Kiyokawa, H.1
Kineman, R.D.2
Manova-Todorova, K.O.3
Soares, V.C.4
Hoffman, E.S.5
Ono, M.6
Khanam, D.7
Hayday, A.C.8
Frohman, L.A.9
Koff, A.10
-
44
-
-
0030010591
-
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
-
Nakayama K, Ishida N, Shirane M, Inomata A, Inoue T, Shishido N, Horii I, Loh DY, Nakayama K: Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 1996, 85:707-720
-
(1996)
Cell
, vol.85
, pp. 707-720
-
-
Nakayama, K.1
Ishida, N.2
Shirane, M.3
Inomata, A.4
Inoue, T.5
Shishido, N.6
Horii, I.7
Loh, D.Y.8
Nakayama, K.9
-
45
-
-
0034544617
-
Cytokine-stimulated T lymphocyte proliferation is regulated by p27Kip1
-
Zhang S, Lawless VA, Kaplan MH: Cytokine-stimulated T lymphocyte proliferation is regulated by p27Kip1. J Immunol 2000, 165: 6270-6277
-
(2000)
J Immunol
, vol.165
, pp. 6270-6277
-
-
Zhang, S.1
Lawless, V.A.2
Kaplan, M.H.3
-
46
-
-
0029163387
-
CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL
-
Boise LH, Minn AJ, Noel PJ, June CH, Accavitti MA, Lindsten T, Thompson CB: CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity 1995, 3:87-98
-
(1995)
Immunity
, vol.3
, pp. 87-98
-
-
Boise, L.H.1
Minn, A.J.2
Noel, P.J.3
June, C.H.4
Accavitti, M.A.5
Lindsten, T.6
Thompson, C.B.7
-
47
-
-
33746729791
-
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
-
Gold R, Linington C, Lassmann H: Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. Brain 2006, 129:1953-1971
-
(2006)
Brain
, vol.129
, pp. 1953-1971
-
-
Gold, R.1
Linington, C.2
Lassmann, H.3
-
48
-
-
12344280009
-
Specificity, magnitude, and kinetics of MOG-specific CD8+ T cell responses during experimental autoimmune encephalomyelitis
-
Ford ML, Evavold BD: Specificity, magnitude, and kinetics of MOG-specific CD8+ T cell responses during experimental autoimmune encephalomyelitis. Eur J Immunol 2005, 35:76-85
-
(2005)
Eur J Immunol
, vol.35
, pp. 76-85
-
-
Ford, M.L.1
Evavold, B.D.2
-
49
-
-
17644396349
-
Immunology of multiple sclerosis
-
Sospedra M, Martin R: Immunology of multiple sclerosis. Annu Rev Immunol 2005, 23:683-747
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 683-747
-
-
Sospedra, M.1
Martin, R.2
-
50
-
-
23444434940
-
Autoreactive CD8+ T cells in multiple sclerosis: A new target for therapy?
-
Friese MA, Fugger L: Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy? Brain 2005, 128:1747-1763
-
(2005)
Brain
, vol.128
, pp. 1747-1763
-
-
Friese, M.A.1
Fugger, L.2
|