Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex

Journal of Experimental Medicine

Volumn 191, Issue 8, 2000, Pages 1395-1412

  Krogsgaard, Michelle ^f   Wucherpfennig, Kai W ^b   Canella, Barbara ^c   Hansen, Bjarke E ^g   Svejgaard, Arne ^g   Pyrdol, Jason ^b   Ditzel, Henrik ^d   Raine, Cedric ^c   Engberg, Jan ^a   Fugger, Lars ^e  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b HARVARD MEDICAL SCHOOL   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e AARHUS UNIVERSITY HOSPITAL   (Denmark)

^f STANFORD UNIVERSITY   (United States)

^g NONE

Author keywords

Antigen presentation; Autoimmunity; Microglia; Multiple sclerosis; Myelin basic protein

Indexed keywords

EPITOPE; HLA DR2 ANTIGEN; INTERLEUKIN 2; LEUKOCYTE ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; MYELIN BASIC PROTEIN;

ANIMAL MODEL; ANTIBODY SPECIFICITY; ANTIGEN DETECTION; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN TISSUE; MACROPHAGE; MAJOR HISTOCOMPATIBILITY COMPLEX; MICROGLIA; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; BINDING SITES; CELL LINE; DROSOPHILA MELANOGASTER; HLA-DR2 ANTIGEN; HUMANS; IMMUNODOMINANT EPITOPES; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED BALB C; MICE, INBRED DBA; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MULTIPLE SCLEROSIS; MYELIN BASIC PROTEINS; PEPTIDE FRAGMENTS; RECOMBINANT PROTEINS;

EID: 0034678450     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.8.1395     Document Type: Article

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