-
1
-
-
0034618094
-
Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction
-
Babbe H, Roers A, Waisman A, Lassmann H, Goebels N, Hohlfeld R, Friese M, Schroder R, Deckert M, Schmidt S, Ravid R, Rajewsky K. 2000. Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction. J Exp Med 192:393-404.
-
(2000)
J Exp Med
, vol.192
, pp. 393-404
-
-
Babbe, H.1
Roers, A.2
Waisman, A.3
Lassmann, H.4
Goebels, N.5
Hohlfeld, R.6
Friese, M.7
Schroder, R.8
Deckert, M.9
Schmidt, S.10
Ravid, R.11
Rajewsky, K.12
-
2
-
-
0029451821
-
The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis
-
Bauer J, Huitinga I, Zhao W, Lassmann H, Hickey WF, Dijkstra CD. 1995. The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis. Glia 15:437-446.
-
(1995)
Glia
, vol.15
, pp. 437-446
-
-
Bauer, J.1
Huitinga, I.2
Zhao, W.3
Lassmann, H.4
Hickey, W.F.5
Dijkstra, C.D.6
-
3
-
-
0032532022
-
Differential expression of inflammatory cytokines parallels progression of central nervous system pathology in two clinically distinct models of multiple sclerosis
-
Begolka WS, Vanderlugt CL, Rahbe SM, Miller SD. 1998. Differential expression of inflammatory cytokines parallels progression of central nervous system pathology in two clinically distinct models of multiple sclerosis. J Immunol 161:4437-4446.
-
(1998)
J Immunol
, vol.161
, pp. 4437-4446
-
-
Begolka, W.S.1
Vanderlugt, C.L.2
Rahbe, S.M.3
Miller, S.D.4
-
4
-
-
0035217962
-
Modes of action of Freund's adjuvants in experimental models of autoimmune diseases
-
Billiau A, Matthys P. 2001. Modes of action of Freund's adjuvants in experimental models of autoimmune diseases. J Leukoc Biol 70:849-860.
-
(2001)
J Leukoc Biol
, vol.70
, pp. 849-860
-
-
Billiau, A.1
Matthys, P.2
-
5
-
-
0037441487
-
Axonal loss in the pathology of MS: Consequences for understanding the progressive phase of the disease
-
Bjartmar C, Wujek JR, Trapp BD. 2003. Axonal loss in the pathology of MS: Consequences for understanding the progressive phase of the disease. J Neurol Sci 206:165-171.
-
(2003)
J Neurol Sci
, vol.206
, pp. 165-171
-
-
Bjartmar, C.1
Wujek, J.R.2
Trapp, B.D.3
-
6
-
-
0021079164
-
Immunohistological analysis of T lymphocyte subsets in the central nervous system in chronic progressive multiple sclerosis
-
Booss J, Esiri MM, Tourtellotte WW, Mason DY. 1983. Immunohistological analysis of T lymphocyte subsets in the central nervous system in chronic progressive multiple sclerosis. J Neurol Sci 62:219-232.
-
(1983)
J Neurol Sci
, vol.62
, pp. 219-232
-
-
Booss, J.1
Esiri, M.M.2
Tourtellotte, W.W.3
Mason, D.Y.4
-
7
-
-
35349024347
-
Induction of the genes for Cxcl9 and Cxcl10 is dependent on IFN-gamma but shows differential cellular expression in experimental autoimmune encephalomyelitis and by astrocytes and microglia in vitro
-
Carter SL, Muller M, Manders PM, Campbell IL. 2007. Induction of the genes for Cxcl9 and Cxcl10 is dependent on IFN-gamma but shows differential cellular expression in experimental autoimmune encephalomyelitis and by astrocytes and microglia in vitro. Glia 55:1728-1739.
-
(2007)
Glia
, vol.55
, pp. 1728-1739
-
-
Carter, S.L.1
Muller, M.2
Manders, P.M.3
Campbell, I.L.4
-
8
-
-
0035941106
-
The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease
-
Chabas D, Baranzini SE, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, Sobel RA, Lock C, Karpuj M, Pedotti R, Heller R, Oksenberg JR, Steinman L. 2001. The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science 294:1731-1735.
-
(2001)
Science
, vol.294
, pp. 1731-1735
-
-
Chabas, D.1
Baranzini, S.E.2
Mitchell, D.3
Bernard, C.C.4
Rittling, S.R.5
Denhardt, D.T.6
Sobel, R.A.7
Lock, C.8
Karpuj, M.9
Pedotti, R.10
Heller, R.11
Oksenberg, J.R.12
Steinman, L.13
-
9
-
-
33644944139
-
Pertussis toxin as an adjuvant suppresses the number and function of CD4+CD25+ T regulatory cells
-
Chen X, Winkler-Pickett RT, Carbonetti NH, Ortaldo JR, Oppenheim JJ, Howard OM. 2006. Pertussis toxin as an adjuvant suppresses the number and function of CD4+CD25+ T regulatory cells. Eur J Immunol 36:671-680.
-
(2006)
Eur J Immunol
, vol.36
, pp. 671-680
-
-
Chen, X.1
Winkler-Pickett, R.T.2
Carbonetti, N.H.3
Ortaldo, J.R.4
Oppenheim, J.J.5
Howard, O.M.6
-
10
-
-
0034601012
-
Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis
-
Chu CQ, Wittmer S, Dalton DK. 2000. Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis. J Exp Med 192:123-128.
-
(2000)
J Exp Med
, vol.192
, pp. 123-128
-
-
Chu, C.Q.1
Wittmer, S.2
Dalton, D.K.3
-
11
-
-
0029671318
-
Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE)
-
Ferber IA, Brocke S, Taylor-Edwards C, Ridgway W, Dinisco C, Steinman L, Dalton D, Fathman CG. 1996. Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE). J Immunol 156:5-7.
-
(1996)
J Immunol
, vol.156
, pp. 5-7
-
-
Ferber, I.A.1
Brocke, S.2
Taylor-Edwards, C.3
Ridgway, W.4
Dinisco, C.5
Steinman, L.6
Dalton, D.7
Fathman, C.G.8
-
12
-
-
23444434940
-
Autoreactive CD8+ T cells in multiple sclerosis: A new target for therapy?
-
Friese MA, Fugger L. 2005. Autoreactive CD8+ T cells in multiple sclerosis: A new target for therapy? Brain 128 (Part 8):1747-1763.
-
(2005)
Brain
, vol.128
, Issue.PART 8
, pp. 1747-1763
-
-
Friese, M.A.1
Fugger, L.2
-
13
-
-
66549130329
-
The relation between inflammation and neurodegeneration in multiple sclerosis brains
-
Frischer JM, Bramow S, Dal-Bianco A, Lucchinetti CF, Rauschka H, Schmidbauer M, Laursen H, Sorensen PS, Lassmann H. 2009. The relation between inflammation and neurodegeneration in multiple sclerosis brains. Brain 132 (Part 5):1175-1189.
-
(2009)
Brain
, vol.132
, Issue.PART 5
, pp. 1175-1189
-
-
Frischer, J.M.1
Bramow, S.2
Dal-Bianco, A.3
Lucchinetti, C.F.4
Rauschka, H.5
Schmidbauer, M.6
Laursen, H.7
Sorensen, P.S.8
Lassmann, H.9
-
14
-
-
0037530542
-
Vulnerability of human neurons to T cell-mediated cytotoxicity
-
Giuliani F, Goodyer CG, Antel JP, Yong VW. 2003. Vulnerability of human neurons to T cell-mediated cytotoxicity. J Immunol 171:368-379.
-
(2003)
J Immunol
, vol.171
, pp. 368-379
-
-
Giuliani, F.1
Goodyer, C.G.2
Antel, J.P.3
Yong, V.W.4
-
15
-
-
33746729791
-
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
-
Gold R, Linington C, Lassmann H. 2006. Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. Brain 129 (Part 8):1953-1971.
-
(2006)
Brain
, vol.129
, Issue.PART 8
, pp. 1953-1971
-
-
Gold, R.1
Linington, C.2
Lassmann, H.3
-
16
-
-
0033565531
-
Regulation of alloantigen-mediated T-cell proliferation by endogenous interferon-gamma: Implications for long-term allograft acceptance
-
Hassan AT, Dai Z, Konieczny BT, Ring GH, Baddoura FK, Abou-Dahab LH, El-Sayed AA, Lakkis FG. 1999. Regulation of alloantigen-mediated T-cell proliferation by endogenous interferon-gamma: Implications for long-term allograft acceptance. Transplantation 68:124-129.
-
(1999)
Transplantation
, vol.68
, pp. 124-129
-
-
Hassan, A.T.1
Dai, Z.2
Konieczny, B.T.3
Ring, G.H.4
Baddoura, F.K.5
Abou-Dahab, L.H.6
El-Sayed, A.A.7
Lakkis, F.G.8
-
17
-
-
0022459287
-
Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions
-
Hauser SL, Bhan AK, Gilles F, Kemp M, Kerr C, Weiner HL. 1986. Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions. Ann Neurol 19:578-587.
-
(1986)
Ann Neurol
, vol.19
, pp. 578-587
-
-
Hauser, S.L.1
Bhan, A.K.2
Gilles, F.3
Kemp, M.4
Kerr, C.5
Weiner, H.L.6
-
19
-
-
20044376483
-
Experimental autoimmune encephalomyelitis repressed by microglial paralysis
-
Heppner FL, Greter M, Marino D, Falsig J, Raivich G, Hovelmeyer N, Waisman A, Rulicke T, Prinz M, Priller J, Becher B, Aguzzi A. 2005. Experimental autoimmune encephalomyelitis repressed by microglial paralysis. Nat Med 11:146-152.
-
(2005)
Nat Med
, vol.11
, pp. 146-152
-
-
Heppner, F.L.1
Greter, M.2
Marino, D.3
Falsig, J.4
Raivich, G.5
Hovelmeyer, N.6
Waisman, A.7
Rulicke, T.8
Prinz, M.9
Priller, J.10
Becher, B.11
Aguzzi, A.12
-
20
-
-
42649135852
-
Pattern of axonal injury in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis: Implications for multiple sclerosis
-
Herrero-Herranz E, Pardo LA, Gold R, Linker RA. 2008. Pattern of axonal injury in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis: Implications for multiple sclerosis. Neurobiol Dis 30:162-173.
-
(2008)
Neurobiol Dis
, vol.30
, pp. 162-173
-
-
Herrero-Herranz, E.1
Pardo, L.A.2
Gold, R.3
Linker, R.A.4
-
21
-
-
0035911254
-
Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis
-
Huang DR, Wang J, Kivisakk P, Rollins BJ, Ransohoff RM. 2001. Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis. J Exp Med 193:713-726.
-
(2001)
J Exp Med
, vol.193
, pp. 713-726
-
-
Huang, D.R.1
Wang, J.2
Kivisakk, P.3
Rollins, B.J.4
Ransohoff, R.M.5
-
22
-
-
0029022855
-
Macrophages in T cell line-mediated, demyelinating, and chronic relapsing experimental autoimmune encephalomyelitis in Lewis rats
-
Huitinga I, Ruuls SR, Jung S, Van Rooijen N, Hartung HP, Dijkstra CD. 1995. Macrophages in T cell line-mediated, demyelinating, and chronic relapsing experimental autoimmune encephalomyelitis in Lewis rats. Clin Exp Immunol 100:344-351.
-
(1995)
Clin Exp Immunol
, vol.100
, pp. 344-351
-
-
Huitinga, I.1
Ruuls, S.R.2
Jung, S.3
Van Rooijen, N.4
Hartung, H.P.5
Dijkstra, C.D.6
-
23
-
-
0025015655
-
Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages
-
Huitinga I, van Rooijen N, de Groot CJ, Uitdehaag BM, Dijkstra CD. 1990. Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages. J Exp Med 172:1025-1033.
-
(1990)
J Exp Med
, vol.172
, pp. 1025-1033
-
-
Huitinga, I.1
van Rooijen, N.2
de Groot, C.J.3
Uitdehaag, B.M.4
Dijkstra, C.D.5
-
24
-
-
0035801332
-
A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis
-
Huseby ES, Liggitt D, Brabb T, Schnabel B, Ohlen C, Goverman J. 2001. A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis. J Exp Med 194:669-676.
-
(2001)
J Exp Med
, vol.194
, pp. 669-676
-
-
Huseby, E.S.1
Liggitt, D.2
Brabb, T.3
Schnabel, B.4
Ohlen, C.5
Goverman, J.6
-
25
-
-
18044382584
-
Cytokines in multiple sclerosis: From bench to bedside
-
Imitola J, Chitnis T, Khoury SJ. 2005. Cytokines in multiple sclerosis: From bench to bedside. Pharmacol Ther 106:163-177.
-
(2005)
Pharmacol Ther
, vol.106
, pp. 163-177
-
-
Imitola, J.1
Chitnis, T.2
Khoury, S.J.3
-
26
-
-
0030846262
-
Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells
-
Itoh Y, Germain RN. 1997. Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells. J Exp Med 186:757-766.
-
(1997)
J Exp Med
, vol.186
, pp. 757-766
-
-
Itoh, Y.1
Germain, R.N.2
-
27
-
-
33646417072
-
The IL-23/IL-17 axis in inflammation
-
Iwakura Y, Ishigame H. 2006. The IL-23/IL-17 axis in inflammation. J Clin Invest 116:1218-1222.
-
(2006)
J Clin Invest
, vol.116
, pp. 1218-1222
-
-
Iwakura, Y.1
Ishigame, H.2
-
28
-
-
0025856061
-
Experimental autoimmune encephalomyelitis is exacerbated by IL-1 alpha and suppressed by soluble IL-1 receptor
-
Jacobs CA, Baker PE, Roux ER, Picha KS, Toivola B, Waugh S, Kennedy MK. 1991. Experimental autoimmune encephalomyelitis is exacerbated by IL-1 alpha and suppressed by soluble IL-1 receptor. J Immunol 146:2983-2989.
-
(1991)
J Immunol
, vol.146
, pp. 2983-2989
-
-
Jacobs, C.A.1
Baker, P.E.2
Roux, E.R.3
Picha, K.S.4
Toivola, B.5
Waugh, S.6
Kennedy, M.K.7
-
29
-
-
0032521030
-
MHC class I-restricted lysis of human oligodendrocytes by myelin basic protein peptide-specific CD8 T lymphocytes
-
Jurewicz A, Biddison WE, Antel JP. 1998. MHC class I-restricted lysis of human oligodendrocytes by myelin basic protein peptide-specific CD8 T lymphocytes. J Immunol 160:3056-3059.
-
(1998)
J Immunol
, vol.160
, pp. 3056-3059
-
-
Jurewicz, A.1
Biddison, W.E.2
Antel, J.P.3
-
30
-
-
33646560965
-
Critical role of M. tuberculosis for dendritic cell maturation to induce collagen-induced arthritis in H-2b background of C57BL/6 mice
-
Kai H, Shibuya K, Wang Y, Kameta H, Kameyama T, Tahara-Hanaoka S, Miyamoto A, Honda S, Matsumoto I, Koyama A, Sumida T, Shibuya A. 2006. Critical role of M. tuberculosis for dendritic cell maturation to induce collagen-induced arthritis in H-2b background of C57BL/6 mice. Immunology 118:233-239.
-
(2006)
Immunology
, vol.118
, pp. 233-239
-
-
Kai, H.1
Shibuya, K.2
Wang, Y.3
Kameta, H.4
Kameyama, T.5
Tahara-Hanaoka, S.6
Miyamoto, A.7
Honda, S.8
Matsumoto, I.9
Koyama, A.10
Sumida, T.11
Shibuya, A.12
-
31
-
-
1242293632
-
Cytosolic phospholipase A2 plays a key role in the pathogenesis of multiple sclerosis-like disease
-
Kalyvas A, David S. 2004. Cytosolic phospholipase A2 plays a key role in the pathogenesis of multiple sclerosis-like disease. Neuron 41:323-335.
-
(2004)
Neuron
, vol.41
, pp. 323-335
-
-
Kalyvas, A.1
David, S.2
-
32
-
-
0030613627
-
MIP-1alpha and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Th1/Th2 lymphocyte differentiation
-
Karpus WJ, Kennedy KJ. 1997. MIP-1alpha and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Th1/Th2 lymphocyte differentiation. J Leukoc Biol 62: 681-687.
-
(1997)
J Leukoc Biol
, vol.62
, pp. 681-687
-
-
Karpus, W.J.1
Kennedy, K.J.2
-
33
-
-
0036283778
-
Relationship between CD4(+)/CD8(+) T cell ratio and T cell activation in multiple myeloma: Reference to IL-16
-
Koike M, Sekigawa I, Okada M, Matsumoto M, Iida N, Hashimoto H, Oshimi K. 2002. Relationship between CD4(+)/CD8(+) T cell ratio and T cell activation in multiple myeloma: Reference to IL-16. Leuk Res 26:705-711.
-
(2002)
Leuk Res
, vol.26
, pp. 705-711
-
-
Koike, M.1
Sekigawa, I.2
Okada, M.3
Matsumoto, M.4
Iida, N.5
Hashimoto, H.6
Oshimi, K.7
-
34
-
-
0032031409
-
IFN-gamma is critical for long-term allograft survival induced by blocking the CD28 and CD40 ligand T cell costimulation pathways
-
Konieczny BT, Dai Z, Elwood ET, Saleem S, Linsley PS, Baddoura FK, Larsen CP, Pearson TC, Lakkis FG. 1998. IFN-gamma is critical for long-term allograft survival induced by blocking the CD28 and CD40 ligand T cell costimulation pathways. J Immunol 160: 2059-2064.
-
(1998)
J Immunol
, vol.160
, pp. 2059-2064
-
-
Konieczny, B.T.1
Dai, Z.2
Elwood, E.T.3
Saleem, S.4
Linsley, P.S.5
Baddoura, F.K.6
Larsen, C.P.7
Pearson, T.C.8
Lakkis, F.G.9
-
35
-
-
0029957071
-
Interferon-gamma confers resistance to experimental allergic encephalomyelitis
-
Krakowski M, Owens T. 1996. Interferon-gamma confers resistance to experimental allergic encephalomyelitis. Eur J Immunol 26:1641-1646.
-
(1996)
Eur J Immunol
, vol.26
, pp. 1641-1646
-
-
Krakowski, M.1
Owens, T.2
-
36
-
-
0037601712
-
CD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells
-
Lapointe R, Bellemare-Pelletier A, Housseau F, Thibodeau J, Hwu P. 2003. CD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells. Cancer Res 63:2836-2843.
-
(2003)
Cancer Res
, vol.63
, pp. 2836-2843
-
-
Lapointe, R.1
Bellemare-Pelletier, A.2
Housseau, F.3
Thibodeau, J.4
Hwu, P.5
-
37
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR, the 2(-Delta Delta C(T)) method
-
Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR, the 2(-Delta Delta C(T)) method. Methods 25:402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
38
-
-
0032588917
-
Relationship between CD4+/CD8+ T cell ratio and T cell activation in systemic lupus erythematosus
-
Maeda N, Sekigawa I, Iida N, Matsumoto M, Hashimoto H, Hirose S. 1999. Relationship between CD4+/CD8+ T cell ratio and T cell activation in systemic lupus erythematosus. Scand J Rheumatol 28:166-170.
-
(1999)
Scand J Rheumatol
, vol.28
, pp. 166-170
-
-
Maeda, N.1
Sekigawa, I.2
Iida, N.3
Matsumoto, M.4
Hashimoto, H.5
Hirose, S.6
-
39
-
-
34347269580
-
Paralysis of CD4(+)CD25(+) regulatory T cell response in chronic autoimmune encephalomyelitis
-
Matsumoto Y, Sakuma H, Kohyama K, Park IK. 2007. Paralysis of CD4(+)CD25(+) regulatory T cell response in chronic autoimmune encephalomyelitis. J Neuroimmunol 187:44-54.
-
(2007)
J Neuroimmunol
, vol.187
, pp. 44-54
-
-
Matsumoto, Y.1
Sakuma, H.2
Kohyama, K.3
Park, I.K.4
-
40
-
-
0033625756
-
Lymphocytes from H2 mice produce lower levels of several cytokines than congenic H2 or H2 mice
-
Matthews VB, Christiansen FT, Price P. 2000. Lymphocytes from H2 mice produce lower levels of several cytokines than congenic H2 or H2 mice. Immunol Cell Biol 78:247-253.
-
(2000)
Immunol Cell Biol
, vol.78
, pp. 247-253
-
-
Matthews, V.B.1
Christiansen, F.T.2
Price, P.3
-
41
-
-
0034517613
-
The H2(b) haplotype modifies the production of pro-inflammatory cytokines: Implications for immunopathology
-
Matthews VB, Price P. 2000. The H2(b) haplotype modifies the production of pro-inflammatory cytokines: Implications for immunopathology. Eur Cytokine Netw 11:640-646.
-
(2000)
Eur Cytokine Netw
, vol.11
, pp. 640-646
-
-
Matthews, V.B.1
Price, P.2
-
42
-
-
0034842960
-
Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes
-
Medana I, Martinic MA, Wekerle H, Neumann H. 2001. Transection of major histocompatibility complex class I-induced neurites by cytotoxic T lymphocytes. Am J Pathol 159:809-815.
-
(2001)
Am J Pathol
, vol.159
, pp. 809-815
-
-
Medana, I.1
Martinic, M.A.2
Wekerle, H.3
Neumann, H.4
-
43
-
-
0034529401
-
MHC class I-restricted killing of neurons by virus-specific CD8+ T lymphocytes is effected through the Fas/FasL, but not the perforin pathway
-
Medana IM, Gallimore A, Oxenius A, Martinic MM, Wekerle H, Neumann H. 2000. MHC class I-restricted killing of neurons by virus-specific CD8+ T lymphocytes is effected through the Fas/FasL, but not the perforin pathway. Eur J Immunol 30:3623-3633.
-
(2000)
Eur J Immunol
, vol.30
, pp. 3623-3633
-
-
Medana, I.M.1
Gallimore, A.2
Oxenius, A.3
Martinic, M.M.4
Wekerle, H.5
Neumann, H.6
-
44
-
-
0029038922
-
A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H-2b mice: Fine specificity and T cell receptor V beta expression of encephalitogenic T cells
-
Mendel I, Kerlero de Rosbo N, Ben-Nun A. 1995. A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H-2b mice: Fine specificity and T cell receptor V beta expression of encephalitogenic T cells. Eur J Immunol 25:1951-1959.
-
(1995)
Eur J Immunol
, vol.25
, pp. 1951-1959
-
-
Mendel, I.1
Kerlero de Rosbo, N.2
Ben-Nun, A.3
-
45
-
-
34548633861
-
Primary-progressive multiple sclerosis
-
Miller DH, Leary SM. 2007. Primary-progressive multiple sclerosis. Lancet Neurol 6:903-912.
-
(2007)
Lancet Neurol
, vol.6
, pp. 903-912
-
-
Miller, D.H.1
Leary, S.M.2
-
46
-
-
0021328623
-
Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice
-
Mokhtarian F, McFarlin DE, Raine CS. 1984. Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice. Nature 309:356-358.
-
(1984)
Nature
, vol.309
, pp. 356-358
-
-
Mokhtarian, F.1
McFarlin, D.E.2
Raine, C.S.3
-
47
-
-
0038459134
-
Molecular mechanisms of axonal damage in inflammatory central nervous system diseases
-
Neumann H. 2003. Molecular mechanisms of axonal damage in inflammatory central nervous system diseases. Curr Opin Neurol 16:267-273.
-
(2003)
Curr Opin Neurol
, vol.16
, pp. 267-273
-
-
Neumann, H.1
-
48
-
-
0036602982
-
Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases
-
Neumann H, Medana IM, Bauer J, Lassmann H. 2002. Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases. Trends Neurosci 25:313-319.
-
(2002)
Trends Neurosci
, vol.25
, pp. 313-319
-
-
Neumann, H.1
Medana, I.M.2
Bauer, J.3
Lassmann, H.4
-
49
-
-
0035869253
-
Axonal degeneration is an early pathological feature in autoimmune-mediated demyelination in mice
-
Onuki M, Ayers MM, Bernard CC, Orian JM. 2001. Axonal degeneration is an early pathological feature in autoimmune-mediated demyelination in mice. Microsc Res Tech 52:731-739.
-
(2001)
Microsc Res Tech
, vol.52
, pp. 731-739
-
-
Onuki, M.1
Ayers, M.M.2
Bernard, C.C.3
Orian, J.M.4
-
50
-
-
30444442133
-
Axon loss is responsible for chronic neurological deficit following inflammatory demyelination in the rat
-
Papadopoulos D, Pham-Dinh D, Reynolds R. 2006. Axon loss is responsible for chronic neurological deficit following inflammatory demyelination in the rat. Exp Neurol 197:373-385.
-
(2006)
Exp Neurol
, vol.197
, pp. 373-385
-
-
Papadopoulos, D.1
Pham-Dinh, D.2
Reynolds, R.3
-
51
-
-
0019465748
-
Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: Requirement for Lyt 1+ 2-T lymphocytes
-
Pettinelli CB, McFarlin DE. 1981. Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: Requirement for Lyt 1+ 2-T lymphocytes. J Immunol 127:1420-1423.
-
(1981)
J Immunol
, vol.127
, pp. 1420-1423
-
-
Pettinelli, C.B.1
McFarlin, D.E.2
-
52
-
-
15944409728
-
Neurofilament phosphoforms: Surrogate markers for axonal injury, degeneration and loss
-
Petzold A. 2005. Neurofilament phosphoforms: Surrogate markers for axonal injury, degeneration and loss. J Neurol Sci 233:183-198.
-
(2005)
J Neurol Sci
, vol.233
, pp. 183-198
-
-
Petzold, A.1
-
53
-
-
0028864801
-
Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha
-
Probert L, Akassoglou K, Pasparakis M, Kontogeorgos G, Kollias G. 1995. Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha. Proc Natl Acad Sci USA 92:11294-11298.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 11294-11298
-
-
Probert, L.1
Akassoglou, K.2
Pasparakis, M.3
Kontogeorgos, G.4
Kollias, G.5
-
54
-
-
0032419459
-
Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE
-
Renno T, Taupin V, Bourbonniere L, Verge G, Tran E, De Simone R, Krakowski M, Rodriguez M, Peterson A, Owens T. 1998. Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE. Mol Cell Neurosci 12:376-389.
-
(1998)
Mol Cell Neurosci
, vol.12
, pp. 376-389
-
-
Renno, T.1
Taupin, V.2
Bourbonniere, L.3
Verge, G.4
Tran, E.5
De Simone, R.6
Krakowski, M.7
Rodriguez, M.8
Peterson, A.9
Owens, T.10
-
55
-
-
33845593313
-
Structure and duration of contact between dendritic cells and T cells are controlled by T cell activation state
-
Rothoeft T, Balkow S, Krummen M, Beissert S, Varga G, Loser K, Oberbanscheidt P, van den Boom F, Grabbe S. 2006. Structure and duration of contact between dendritic cells and T cells are controlled by T cell activation state. Eur J Immunol 36:3105-3117.
-
(2006)
Eur J Immunol
, vol.36
, pp. 3105-3117
-
-
Rothoeft, T.1
Balkow, S.2
Krummen, M.3
Beissert, S.4
Varga, G.5
Loser, K.6
Oberbanscheidt, P.7
van den Boom, F.8
Grabbe, S.9
-
56
-
-
0000337323
-
Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein
-
Slavin A, Ewing C, Liu J, Ichikawa M, Slavin J, Bernard CC. 1998. Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein. Autoimmunity 28:109-120.
-
(1998)
Autoimmunity
, vol.28
, pp. 109-120
-
-
Slavin, A.1
Ewing, C.2
Liu, J.3
Ichikawa, M.4
Slavin, J.5
Bernard, C.C.6
-
57
-
-
31544435227
-
Differential expression of suppressors of cytokine signaling-1 and -3 and related cytokines in central nervous system during remitting versus non-remitting forms of experimental autoimmune encephalomyelitis
-
Stark JL, Cross AH. 2006. Differential expression of suppressors of cytokine signaling-1 and -3 and related cytokines in central nervous system during remitting versus non-remitting forms of experimental autoimmune encephalomyelitis. Int Immunol 18:347-353.
-
(2006)
Int Immunol
, vol.18
, pp. 347-353
-
-
Stark, J.L.1
Cross, A.H.2
-
58
-
-
0036305186
-
Multiple sclerosis: Deeper understanding of its pathogenesis reveals new targets for therapy
-
Steinman L, Martin R, Bernard C, Conlon P, Oksenberg JR. 2002. Multiple sclerosis: Deeper understanding of its pathogenesis reveals new targets for therapy. Annu Rev Neurosci 25:491-505.
-
(2002)
Annu Rev Neurosci
, vol.25
, pp. 491-505
-
-
Steinman, L.1
Martin, R.2
Bernard, C.3
Conlon, P.4
Oksenberg, J.R.5
-
59
-
-
33745728404
-
How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis
-
Steinman L, Zamvil SS. 2006. How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis. Ann Neurol 60:12-21.
-
(2006)
Ann Neurol
, vol.60
, pp. 12-21
-
-
Steinman, L.1
Zamvil, S.S.2
-
60
-
-
0035877190
-
Myelin antigen-specific CD81 T cells are encephalitogenic and produce severe disease in C57BL/6 mice
-
Sun D, Whitaker JN, Huang Z, Liu D, Coleclough C, Wekerle H, Raine CS. 2001. Myelin antigen-specific CD81 T cells are encephalitogenic and produce severe disease in C57BL/6 mice. J Immunol 166:7579-7587.
-
(2001)
J Immunol
, vol.166
, pp. 7579-7587
-
-
Sun, D.1
Whitaker, J.N.2
Huang, Z.3
Liu, D.4
Coleclough, C.5
Wekerle, H.6
Raine, C.S.7
-
61
-
-
0032193213
-
Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice
-
Tran EH, Hoekstra K, van Rooijen N, Dijkstra CD, Owens T. 1998. Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice. J Immunol 161:3767-3775.
-
(1998)
J Immunol
, vol.161
, pp. 3767-3775
-
-
Tran, E.H.1
Hoekstra, K.2
van Rooijen, N.3
Dijkstra, C.D.4
Owens, T.5
-
62
-
-
0034162486
-
IFN-gamma shapes immune invasion of the central nervous system via regulation of chemokines
-
Tran EH, Prince EN, Owens T. 2000. IFN-gamma shapes immune invasion of the central nervous system via regulation of chemokines. J Immunol 164:2759-2768.
-
(2000)
J Immunol
, vol.164
, pp. 2759-2768
-
-
Tran, E.H.1
Prince, E.N.2
Owens, T.3
-
63
-
-
44649187461
-
Differential effects of interleukin-1 alpha and beta on interleukin-6 and chemokine synthesis in neurones
-
Tsakiri N, Kimber I, Rothwell NJ, Pinteaux E. 2008. Differential effects of interleukin-1 alpha and beta on interleukin-6 and chemokine synthesis in neurones. Mol Cell Neurosci 38:259-265.
-
(2008)
Mol Cell Neurosci
, vol.38
, pp. 259-265
-
-
Tsakiri, N.1
Kimber, I.2
Rothwell, N.J.3
Pinteaux, E.4
-
64
-
-
0023902649
-
Myelin proteolipid proteininduced experimental allergic encephalomyelitis. Variations of disease expression in different strains of mice
-
Tuohy VK, Sobel RA, Lees MB. 1988. Myelin proteolipid proteininduced experimental allergic encephalomyelitis. Variations of disease expression in different strains of mice. J Immunol 140:1868-1873.
-
(1988)
J Immunol
, vol.140
, pp. 1868-1873
-
-
Tuohy, V.K.1
Sobel, R.A.2
Lees, M.B.3
-
65
-
-
13544273533
-
-
van Beek J, van Meurs M, t Hart BA, Brok HP, Neal JW, Chatagner A, Harris CL, Omidvar N, Morgan BP, Laman JD, Gasque P. 2005. Decay-accelerating factor (CD55) is expressed by neurons in response to chronic but not acute autoimmune central nervous system inflammation associated with complement activation. J Immunol 174:2353-2365.
-
van Beek J, van Meurs M, t Hart BA, Brok HP, Neal JW, Chatagner A, Harris CL, Omidvar N, Morgan BP, Laman JD, Gasque P. 2005. Decay-accelerating factor (CD55) is expressed by neurons in response to chronic but not acute autoimmune central nervous system inflammation associated with complement activation. J Immunol 174:2353-2365.
-
-
-
-
66
-
-
4143136628
-
Cytotoxic lymphocytes; instigators of dramatic target cell death
-
Waterhouse NJ, Clarke CJ, Sedelies KA, Teng MW, Trapani JA. 2004. Cytotoxic lymphocytes; instigators of dramatic target cell death. Biochem Pharmacol 68:1033-1040.
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 1033-1040
-
-
Waterhouse, N.J.1
Clarke, C.J.2
Sedelies, K.A.3
Teng, M.W.4
Trapani, J.A.5
-
67
-
-
0033571331
-
IFN-gamma is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: A possible role for nitric oxide
-
Willenborg DO, Fordham SA, Staykova MA, Ramshaw IA, Cowden WB. 1999. IFN-gamma is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: A possible role for nitric oxide. J Immunol 163:5278-5286.
-
(1999)
J Immunol
, vol.163
, pp. 5278-5286
-
-
Willenborg, D.O.1
Fordham, S.A.2
Staykova, M.A.3
Ramshaw, I.A.4
Cowden, W.B.5
-
68
-
-
0036136532
-
Axon loss in the spinal cord determines permanent neurological disability in an animal model of multiple sclerosis
-
Wujek JR, Bjartmar C, Richer E, Ransohoff RM, Yu M, Tuohy VK, Trapp BD. 2002. Axon loss in the spinal cord determines permanent neurological disability in an animal model of multiple sclerosis. J Neuropathol Exp Neurol 61:23-32.
-
(2002)
J Neuropathol Exp Neurol
, vol.61
, pp. 23-32
-
-
Wujek, J.R.1
Bjartmar, C.2
Richer, E.3
Ransohoff, R.M.4
Yu, M.5
Tuohy, V.K.6
Trapp, B.D.7
-
69
-
-
1242295163
-
T cell and antibody responses in remitting-relapsing experimental autoimmune encephalomyelitis in (C57BL/6 x SJL) F1 mice
-
Zhang GX, Yu S, Gran B, Li J, Calida D, Ventura E, Chen X, Rostami A. 2004. T cell and antibody responses in remitting-relapsing experimental autoimmune encephalomyelitis in (C57BL/6 x SJL) F1 mice. J Neuroimmunol 148:1-10.
-
(2004)
J Neuroimmunol
, vol.148
, pp. 1-10
-
-
Zhang, G.X.1
Yu, S.2
Gran, B.3
Li, J.4
Calida, D.5
Ventura, E.6
Chen, X.7
Rostami, A.8
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