Tolerization of dendritic cells by Ts cells: The crucial role of inhibitory receptors ILT3 and ILT4

Nature Immunology

Volumn 3, Issue 3, 2002, Pages 237-243

  Chang, C C ^a   Ciubotariu, R ^a   Manavalan, J S ^a   Yuan, J ^a   Colovai, A I ^a   Piazza, F ^a   Lederman, S ^a   Colonna, M ^b   Cortesini, R ^c   Dalla Favera, R ^a   Suciu Foca, N ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; CD28 ANTIGEN; CD8 ANTIGEN; CELL RECEPTOR; IMMUNOGLOBULIN LIKE TRANSCRIPT 3; IMMUNOGLOBULIN LIKE TRANSCRIPT 4; UNCLASSIFIED DRUG;

ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; ARTICLE; CIRCULATION; CONTROLLED STUDY; DENDRITIC CELL; GRAFT REJECTION; HEART TRANSPLANTATION; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; MONOCYTE; ORGAN DONOR; PRIORITY JOURNAL; RECEPTOR UPREGULATION; RECIPIENT; SUPPRESSOR CELL; T LYMPHOCYTE;

ANTIGEN-PRESENTING CELLS; ANTIGENS, CD28; ANTIGENS, CD8; DENDRITIC CELLS; HUMANS; IMMUNE TOLERANCE; MEMBRANE GLYCOPROTEINS; NF-KAPPA B; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; T-LYMPHOCYTES, REGULATORY;

EID: 0036122891     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni760     Document Type: Article

References (49)

1. Regulatory T cells: Key controllers of immunologic self-tolerance
2. Differentiation of T regulatory cells by immature dendritic cells
3. Certified professionals: CD4(+)CD25(+) suppressor T cells
4. Regulatory T cells in autoimmunity
5. Human CD25(+)CD4(+) T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
6. + regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
7. Strategies for designing and optimizing new generation vaccines
8. Cytotoxic lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
9. Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood
10. + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
11. Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells
12. −T cells
13. − regulatory T cells
14. Induction of MHC-class 1 restricted human suppressor T cells by peptide priming in vitro
15. −T cells
16. Inhibition of CD40 signaling pathway in antigen presenting cells by T suppressor cells
17. T suppressor lymphocytes inhibit NFκB-mediated transcription of CD86 gene in APC
18. Alloantigen-specific cytotoxic and suppressor T lymphocytes are derived from phenotypically distinct precursors
19. + progenitor to dendritic cell differentiation from a human cell line model
20. A novel family of lg-like receptors for HLA class 1 molecules that modulate function of lymphoid and myeloid cells
21. A family of inhibitory and activating lg-like receptors that modulate function of lymphoid and myeloid cells
22. Cutting edge: Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class 1 molecules
23. Immune inhibitory receptors
24. A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing
25. Detection of T suppressor cells in patients with organ allografts
26. T lymphocyte T cell-B cell-activating molecule/CD40-L molecules induce normal B cells or chronic lymphocytic leukemia B cells to express CD80 (B7/BB-1) and enhance their costimulatory activity
27. CD28 expression on peripheral blood T lymphocytes after orthotopic liver transplant upregulation in acute rejection
28. Models of T cell anergy: Is there a common molecular mechanism?
29. Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo
30. Glucocorticoids transform CD40-triggering of dendritic cells into an alternative activation pathway resulting in antigen-presenting cells that secrete IL-10
31. 1 α, 25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation
32. Immature dendritic cells generated with low doses of GM-CSF in the absence of IL-4 are maturation resistant and prolong allograft survival in vivo
33. Dendritic cells in transplantation-friend or foe?
34. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
35. Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene
36. The dendritic cell system and its role in immunogenicity
37. The induction of tolerance by dendritic cells that have captured apoptotic cells
38. Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
39. Interleukin-10 and the interleukin-10 receptor
40. Distinct mRNA microarray profiles of tolerogenic dendritic cells
41. Immunology. Licence to kill
42. Immunbiology of dendritic cells
43. Persistent allopeptide reactivity and epitope spreading in chronic rejection of organ allografts
44. Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood
45. Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability
46. Monitoring mRNA expression by polymerase chain reaction: The "primer-dropping" method
47. Retroviral expression in Embryonic stem cells and hematopoetic stem cells
48. Centrifugal enhancement of retroviral mediated gene transfer
49. Rearranged NF-κB-2 genes in lymphoid neoplasms code for constitutively active nuclear transactivators