-
1
-
-
58149337392
-
Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling
-
Akerfeldt MC, Howes J, Chan JY, Stevens VA, Boubenna N, McGuire HM, King C, Biden TJ & Laybutt DR 2008 Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling. Diabetes 57 3034-3044.
-
(2008)
Diabetes
, vol.57
, pp. 3034-3044
-
-
Akerfeldt, M.C.1
Howes, J.2
Chan, J.Y.3
Stevens, V.A.4
Boubenna, N.5
McGuire, H.M.6
King, C.7
Biden, T.J.8
Laybutt, D.R.9
-
2
-
-
33646561549
-
ERK3 associates with MAP2 and is involved in glucose-induced insulin secretion
-
Anhê GF, Torrão AS, Nogueira TC, Caperuto LC, Amaral ME, Medina MC, Azevedo-Martins AK, Carpinelli AR, Carvalho CR, Curi R et al. 2006 ERK3 associates with MAP2 and is involved in glucose-induced insulin secretion. Molecular and Cellular Endocrinology 251 33-41.
-
(2006)
Molecular and Cellular Endocrinology
, vol.251
, pp. 33-41
-
-
Anhê, G.F.1
Torrão, A.S.2
Nogueira, T.C.3
Caperuto, L.C.4
Amaral, M.E.5
Medina, M.C.6
Azevedo-Martins, A.K.7
Carpinelli, A.R.8
Carvalho, C.R.9
Curi, R.10
-
3
-
-
35848967815
-
2+-ATPase 2 expression by prolactin and glucocorticoids is involved in the adaptation of insulin secretory response during the peripartum period
-
2+-ATPase 2 expression by prolactin and glucocorticoids is involved in the adaptation of insulin secretory response during the peripartum period. Journal of Endocrinology 195 17-27.
-
(2007)
Journal of Endocrinology
, vol.195
, pp. 17-27
-
-
Anhê, G.F.1
Nogueira, T.C.2
Nicoletti-Carvalho, J.E.3
Lellis-Santos, C.4
Barbosa, H.C.5
Cipolla-Neto, J.6
Bosqueiro, J.R.7
Boschero, A.C.8
Bordin, S.9
-
4
-
-
77249137169
-
Smad5 regulates Akt2 expression and insulin-induced glucose uptake in L6 myotubes
-
Anhê FF, Lellis-Santos C, Leite AR, Hirabara SM, Boschero AC, Curi R, Anhê GF & Bordin S 2010 Smad5 regulates Akt2 expression and insulin-induced glucose uptake in L6 myotubes. Molecular and Cellular Endocrinology 319 30-38.
-
(2010)
Molecular and Cellular Endocrinology
, vol.319
, pp. 30-38
-
-
Anhê, F.F.1
Lellis-Santos, C.2
Leite, A.R.3
Hirabara, S.M.4
Boschero, A.C.5
Curi, R.6
Anhê, G.F.7
Bordin, S.8
-
5
-
-
33746190686
-
Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells
-
DOI 10.1016/j.tiv.2006.02.007, PII S088723330600035X
-
Azevedo-Martins AK, Monteiro AP, Lima CL, Lenzen S & Curi R 2006 Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells. Toxicology In Vitro 20 1106-1113. (Pubitemid 44088590)
-
(2006)
Toxicology in Vitro
, vol.20
, Issue.7
, pp. 1106-1113
-
-
Azevedo-Martins, A.K.1
Monteiro, A.P.2
Lima, C.L.3
Lenzen, S.4
Curi, R.5
-
6
-
-
4344716950
-
Fatty acid protection from palmitic acid-induced apoptosis is lost following PI3-kinase inhibition
-
DOI 10.1023/B:APPT.0000038039.82506.0c
-
Beeharry N, Chambers JA & Green IC 2004 Fatty acid protection from palmitic acid-induced apoptosis is lost following PI3-kinase inhibition. Apoptosis 9 599-607. (Pubitemid 39158636)
-
(2004)
Apoptosis
, vol.9
, Issue.5
, pp. 599-607
-
-
Beeharry, N.1
Chambers, J.A.2
Green, I.C.3
-
7
-
-
0035862989
-
Endotoxin-mediated delayed islet graft function is associated with increased intra-islet cytokine production and islet cell apoptosis
-
Berney T, Damaris Molano R, Cattan P, Pileggi A, Vizzardelli C, Oliver R, Ricordi C & Inverardi L 2001 Endotoxin-mediated delayed islet graft function is associated with increased intra-islet cytokine production and islet cell apoptosis. Transplantation 71 125-132. (Pubitemid 32105789)
-
(2001)
Transplantation
, vol.71
, Issue.1
, pp. 125-132
-
-
Berney, T.1
Molano, R.D.2
Cattan, P.3
Pileggi, A.4
Vizzardelli, C.5
Oliver, R.6
Ricordi, C.7
Inverardi, L.8
-
9
-
-
34948813565
-
Leptin decreases apoptosis and alters BCL-2:Bax ratio in clonal rodent pancreatic beta-cells
-
Brown JEP & Dunmore SJ 2007 Leptin decreases apoptosis and alters BCL-2:Bax ratio in clonal rodent pancreatic beta-cells. Diabetes/Metabolism Research and Reviews 23 497-502.
-
(2007)
Diabetes/Metabolism Research and Reviews
, vol.23
, pp. 497-502
-
-
Brown, J.E.P.1
Dunmore, S.J.2
-
10
-
-
2942564469
-
IL-6 protects pancreatic islet b cells from proinflammatory cytokines-induced cell death and functional impairment in vitro and in vivo
-
Choi SE, Choi KM, Yoon IH, Shin JY, Kim JS, Park WY, Han DJ, Kim SC, Ahn C, Kim JY et al. 2004 IL-6 protects pancreatic islet b cells from proinflammatory cytokines-induced cell death and functional impairment in vitro and in vivo. Transplant Immunology 13 43-53.
-
(2004)
Transplant Immunology
, vol.13
, pp. 43-53
-
-
Choi, S.E.1
Choi, K.M.2
Yoon, I.H.3
Shin, J.Y.4
Kim, J.S.5
Park, W.Y.6
Han, D.J.7
Kim, S.C.8
Ahn, C.9
Kim, J.Y.10
-
11
-
-
33644749322
-
Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: Many differences, few similarities
-
Cnop M, Welsh N, Jonas JC, Jörns A, Lenzen S & Eizirik DL 2005 Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities. Diabetes 54 S97-S107.
-
(2005)
Diabetes
, vol.54
-
-
Cnop, M.1
Welsh, N.2
Jonas, J.C.3
Jörns, A.4
Lenzen, S.5
Eizirik, D.L.6
-
13
-
-
44949214679
-
Differential regulation of the endoplasmic reticulum stress response in pancreatic β-cells exposed to long-chain saturated and monounsaturated fatty acids
-
DOI 10.1677/JOE-08-0041
-
Diakogiannaki E, Welters HJ & Morgan NG 2008 Differential regulation of the endoplasmic reticulum stress response in pancreatic b-cells exposed to long-chain saturated and monounsaturated fatty acids. Journal of Endocrinology 197 553-563. (Pubitemid 351803959)
-
(2008)
Journal of Endocrinology
, vol.197
, Issue.3
, pp. 553-563
-
-
Diakogiannaki, E.1
Welters, H.J.2
Morgan, N.G.3
-
14
-
-
0028568369
-
Local production of human IL-6 promotes insulitis but retards the onset of insulin-dependent diabetes mellitus in non-obese diabetic mice
-
DiCosmo BF, Picarella D & Flavell RA 1994 Local production of human IL-6 promotes insulitis but retards the onset of insulin-dependent diabetes mellitus in non-obese diabetic mice. International Immunology 6 1829-1837.
-
(1994)
International Immunology
, vol.6
, pp. 1829-1837
-
-
DiCosmo, B.F.1
Picarella, D.2
Flavell, R.A.3
-
15
-
-
33644747390
-
Mechanisms of beta-cell death in type 2 diabetes
-
Donath MY, Ehses JA, Maedler K, Schumann DM, Ellingsgaard H, Eppler E & Reinecke M 2005 Mechanisms of beta-cell death in type 2 diabetes. Diabetes 54 108-113.
-
(2005)
Diabetes
, vol.54
, pp. 108-113
-
-
Donath, M.Y.1
Ehses, J.A.2
Maedler, K.3
Schumann, D.M.4
Ellingsgaard, H.5
Eppler, E.6
Reinecke, M.7
-
16
-
-
0038242819
-
TRB3: A tribbles homolog that inhibits Akt/PKB activation by insulin in liver
-
DOI 10.1126/science.1079817
-
Du K, Herzig S, Kulkarni RN & Montminy M 2003 TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science 300 1574-1577. (Pubitemid 36682889)
-
(2003)
Science
, vol.300
, Issue.5625
, pp. 1574-1577
-
-
Du, K.1
Herzig, S.2
Kulkarni, R.N.3
Montminy, M.4
-
17
-
-
35148833815
-
Regulation of β-cell mass and function by the Akt/protein kinase B signalling pathway
-
DOI 10.1111/j.1463-1326.2007.00783.x
-
Elghazi L, Rachdi L, Weiss AJ, Cras-Méneur C & Bernal-Mizrachi E 2007 Regulation of beta-cell mass and function by the Akt/protein kinase B signalling pathway. Diabetes, Obesity & Metabolism 9 147-157. (Pubitemid 47543137)
-
(2007)
Diabetes, Obesity and Metabolism
, vol.9
, Issue.SUPPL. 2
, pp. 147-157
-
-
Elghazi, L.1
Rachdi, L.2
Weiss, A.J.3
Cras-Meneur, C.4
Bernal-Mizrachi, E.5
-
18
-
-
51349133256
-
Interleukin-6 regulates pancreatic alpha-cell mass expansion
-
Ellingsgaard H, Ehses JA, Hammar EB, Van Lommel L, Quintens R, Martens G, Kerr-Conte J, Pattou F, Berney T, Pipeleers D et al. 2008 Interleukin-6 regulates pancreatic alpha-cell mass expansion. PNAS 105 13163-13168.
-
(2008)
PNAS
, vol.105
, pp. 13163-13168
-
-
Ellingsgaard, H.1
Ehses, J.A.2
Hammar, E.B.3
Van Lommel, L.4
Quintens, R.5
Martens, G.6
Kerr-Conte, J.7
Pattou, F.8
Berney, T.9
Pipeleers, D.10
-
19
-
-
37249073840
-
Role of interleukin-6 signalling in glucose and lipid metabolism
-
DOI 10.1111/j.1748-1716.2007.01779.x
-
Glund S & Krook A 2008 Role of interleukin-6 signalling in glucose and lipid metabolism. Acta Physiologica 192 37-48. (Pubitemid 350265360)
-
(2008)
Acta Physiologica
, vol.192
, Issue.1
, pp. 37-48
-
-
Glund, S.1
Krook, A.2
-
20
-
-
2942523253
-
Insulin secretory defects and impaired islet architecture in pancreatic beta-cell-specific STAT3 knockout mice
-
Gorogawa S, Fujitani Y, Kaneto H, Hazama Y, Watada H, Miyamoto Y, Takeda K, Akira S, Magnuson MA, Yamasaki Yet al. 2004 Insulin secretory defects and impaired islet architecture in pancreatic beta-cell-specific STAT3 knockout mice. Biochemical and Biophysical Research Communications 319 1159-1170.
-
(2004)
Biochemical and Biophysical Research Communications
, vol.319
, pp. 1159-1170
-
-
Gorogawa, S.1
Fujitani, Y.2
Kaneto, H.3
Hazama, Y.4
Watada, H.5
Miyamoto, Y.6
Takeda, K.7
Akira, S.8
Magnuson, M.A.9
Yamasaki, Y.10
-
21
-
-
0033511647
-
How are free fatty acids transported in membranes? Is it by proteins or by free diffusion through the lipids?
-
Hamilton JA & Kamp F 1999 How are free fatty acids transported in membranes? Is it by proteins or by free diffusion through the lipids? Diabetes 48 2255-2269.
-
(1999)
Diabetes
, vol.48
, pp. 2255-2269
-
-
Hamilton, J.A.1
Kamp, F.2
-
22
-
-
0036895383
-
Endoplasmic reticulum stress and the development of diabetes: A review
-
Harding HP & Ron D 2002 Endoplasmic reticulum stress and the development of diabetes: a review. Diabetes 51 S455-S461. (Pubitemid 35403430)
-
(2002)
Diabetes
, vol.51
, Issue.SUPPL. 3
-
-
Harding, H.P.1
Ron, D.2
-
23
-
-
33749322246
-
Systemic immune mediators and lifestyle changes in the prevention of type 2 diabetes: Results from the Finnish Diabetes Prevention Study
-
DOI 10.2337/db05-1320
-
Herder C, Peltonen M, Koenig W, Kräft I, Müller-Scholze S, Martin S, Lakka T, Ilanne-Parikka P, Eriksson JG, Hämäläinen H et al. 2006 Systemic immune mediators and lifestyle changes in the prevention of type 2 diabetes: results from the Finnish Diabetes Prevention Study. Diabetes 55 2340-2346. (Pubitemid 44743633)
-
(2006)
Diabetes
, vol.55
, Issue.8
, pp. 2340-2346
-
-
Herder, C.1
Peltonen, M.2
Koenig, W.3
Kraft, I.4
Muller-Scholze, S.5
Martin, S.6
Lakka, T.7
Ilanne-Parikka, P.8
Eriksson, J.G.9
Hamalainen, H.10
Keinanen-Kiukaanniemi, S.11
Valle, T.T.12
Uusitupa, M.13
Lindstrom, J.14
Kolb, H.15
Tuomilehto, J.16
-
24
-
-
2442715069
-
Interleukin-6 activates phosphoinositol-3′ kinase in multiple myeloma tumor cells by signaling through RAS-dependent and, separately, through p85-dependent pathways
-
Hsu JH, Shi Y, Frost P, Yan H, Hoang B, Sharma S, Gera J & Lichtenstein A 2004 Interleukin-6 activates phosphoinositol-3′ kinase in multiple myeloma tumor cells by signaling through RAS-dependent and, separately, through p85-dependent pathways. Oncogene 23 3368-3375.
-
(2004)
Oncogene
, vol.23
, pp. 3368-3375
-
-
Hsu, J.H.1
Shi, Y.2
Frost, P.3
Yan, H.4
Hoang, B.5
Sharma, S.6
Gera, J.7
Lichtenstein, A.8
-
26
-
-
33745116619
-
Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic β-cell apoptosis
-
DOI 10.1210/en.2005-1494
-
Karaskov E, Scott C, Zhang L, Teodoro T, Ravazzola M & Volchuk A 2006 Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis. Endocrinology 147 3398-3407. (Pubitemid 43901131)
-
(2006)
Endocrinology
, vol.147
, Issue.7
, pp. 3398-3407
-
-
Karaskov, E.1
Scott, C.2
Zhang, L.3
Teodoro, T.4
Ravazzola, M.5
Volchuk, A.6
-
27
-
-
9244231766
-
Free fatty acids and cytokines induce pancreatic β-cell apoptosis by different mechanisms: Role of nuclear factor-κB and endoplasmic reticulum stress
-
DOI 10.1210/en.2004-0478
-
Kharroubi I, Ladriere L, Cardozo AK, Dogusan Z, Cnop M & Eizirik DL 2004 Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress. Endocrinology 145 5087-5096. (Pubitemid 39551129)
-
(2004)
Endocrinology
, vol.145
, Issue.11
, pp. 5087-5096
-
-
Kharroubi, I.1
Ladriere, L.2
Cardozo, A.K.3
Dogusan, Z.4
Cnop, M.5
Eizirik, D.L.6
-
28
-
-
20444491588
-
Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression
-
Kim SJ, Winter K, Nian C, Tsuneoka M, Koda Y & McIntosh CH 2005 Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression. Journal of Biological Chemistry 280 22297-22307.
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 22297-22307
-
-
Kim, S.J.1
Winter, K.2
Nian, C.3
Tsuneoka, M.4
Koda, Y.5
McIntosh, C.H.6
-
29
-
-
0035854780
-
Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL
-
Kovalovich K, Li W, DeAngelis R, Greenbaum LE, Ciliberto G & Taub R 2001 Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL. Journal of Biological Chemistry 276 26605-26613.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 26605-26613
-
-
Kovalovich, K.1
Li, W.2
DeAngelis, R.3
Greenbaum, L.E.4
Ciliberto, G.5
Taub, R.6
-
30
-
-
33644755633
-
Interleukin-6 and diabetes: The good, the bad, or the indifferent?
-
Kristiansen OP & Mandrup-Poulsen P 2005 Interleukin-6 and diabetes: the good, the bad, or the indifferent? Diabetes 54 S114-S124.
-
(2005)
Diabetes
, vol.54
-
-
Kristiansen, O.P.1
Mandrup-Poulsen, P.2
-
31
-
-
33847677975
-
Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes
-
DOI 10.1007/s00125-006-0590-z
-
Laybutt DR, Preston AM, Akerfeldt MC, Kench JG, Busch AK, Biankin AV & Biden TJ 2007 Endoplasmic reticulum stress contributes to beta cell apoptosis in type 2 diabetes. Diabetologia 50 752-763. (Pubitemid 46355827)
-
(2007)
Diabetologia
, vol.50
, Issue.4
, pp. 752-763
-
-
Laybutt, D.R.1
Preston, A.M.2
Akerfeldt, M.C.3
Kench, J.G.4
Busch, A.K.5
Biankin, A.V.6
Biden, T.J.7
-
32
-
-
0035710746
-
-δδCT method
-
DOI 10.1006/meth.2001.1262
-
Livak KJ & Schmittgen TD 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25 402-408. (Pubitemid 34164012)
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
33
-
-
42449126643
-
Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis
-
Martinez SC, Tanabe K, Cras-Méneur C, Abumrad NA, Bernal-Mizrachi E & Permutt MA 2008 Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis. Diabetes 57 846-859.
-
(2008)
Diabetes
, vol.57
, pp. 846-859
-
-
Martinez, S.C.1
Tanabe, K.2
Cras-Méneur, C.3
Abumrad, N.A.4
Bernal-Mizrachi, E.5
Permutt, M.A.6
-
34
-
-
0035144493
-
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl-2 and perturbing the cellular redox state
-
McCullough KD, Martindale JL, Klotz LO, Aw TY & Holbrook NJ 2001 Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl-2 and perturbing the cellular redox state. Molecular and Cellular Biology 21 1249-1259.
-
(2001)
Molecular and Cellular Biology
, vol.21
, pp. 1249-1259
-
-
McCullough, K.D.1
Martindale, J.L.2
Klotz, L.O.3
Aw, T.Y.4
Holbrook, N.J.5
-
35
-
-
0030735542
-
Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-α, in vivo
-
Mohamed-Ali V, Goodrick S, Rawesh A, Katz DR, Miles JM, Yudkin JS, Klein S & Coppack SW 1997 Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo. Journal of Clinical Endocrinology and Metabolism 82 4196-4200. (Pubitemid 27525539)
-
(1997)
Journal of Clinical Endocrinology and Metabolism
, vol.82
, Issue.12
, pp. 4196-4200
-
-
Mohamed-Ali, V.1
Goodrick, S.2
Rawesh, A.3
Katz, D.R.4
Miles, J.M.5
Yudkin, J.S.6
Klein, S.7
Coppack, S.W.8
-
36
-
-
17144417669
-
TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death
-
DOI 10.1038/sj.emboj.7600596
-
Ohoka N, Yoshii S, Hattori T, Onozaki K & Hayashi H 2005 TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death. EMBO Journal 24 1243-1255. (Pubitemid 40516607)
-
(2005)
EMBO Journal
, vol.24
, Issue.6
, pp. 1243-1255
-
-
Ohoka, N.1
Yoshii, S.2
Hattori, T.3
Onozaki, K.4
Hayashi, H.5
-
37
-
-
1942539048
-
Interleukin-6 protects MIN6 beta cells from cytokine-induced apoptosis
-
Park H, Ahn Y, Park CK, Chung HY & Park Y 2003 Interleukin-6 protects MIN6 beta cells from cytokine-induced apoptosis. Annals of the New York Academy of Sciences 1005 242-249.
-
(2003)
Annals of the New York Academy of Sciences
, vol.1005
, pp. 242-249
-
-
Park, H.1
Ahn, Y.2
Park, C.K.3
Chung, H.Y.4
Park, Y.5
-
38
-
-
34047235220
-
Transcriptional regulation of the endoplasmic reticulum stress gene chop in pancreatic insulin-producing cells
-
DOI 10.2337/db06-1253
-
Pirot P, Ortis F, Cnop M, Ma Y, Hendershot LM, Eizirik DL & Cardozo AK 2007 Transcriptional regulation of the endoplasmic reticulum stress gene chop in pancreatic insulin-producing cells. Diabetes 56 1069-1077. (Pubitemid 46540305)
-
(2007)
Diabetes
, vol.56
, Issue.4
, pp. 1069-1077
-
-
Pirot, P.1
Ortis, F.2
Cnop, M.3
Ma, Y.4
Hendershot, L.M.5
Eizirik, D.L.6
Cardozo, A.K.7
-
39
-
-
57449102900
-
TRI3 is implicated in glucotoxicity- and endoplasmic reticulum-stress- induced beta-cell apoptosis
-
Qian B, Wang H, Men X, Zhang W, Cai H, Xu S, Xu Y, Ye L, Wollheim CB & Lou J 2008 TRI3 is implicated in glucotoxicity- and endoplasmic reticulum-stress-induced beta-cell apoptosis. Journal of Endocrinology 199 407-416.
-
(2008)
Journal of Endocrinology
, vol.199
, pp. 407-416
-
-
Qian, B.1
Wang, H.2
Men, X.3
Zhang, W.4
Cai, H.5
Xu, S.6
Xu, Y.7
Ye, L.8
Wollheim, C.B.9
Lou, J.10
-
40
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
DOI 10.1038/nrm2199, PII NRM2199
-
Ron D & Walter P 2007 Signal integration in the endoplasmic reticulum unfolded protein response. Nature Reviews. Molecular Cell Biology 8 519-529. (Pubitemid 46985379)
-
(2007)
Nature Reviews Molecular Cell Biology
, vol.8
, Issue.7
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
41
-
-
0025159212
-
Interleukin-6 affects insulin secretion and glucose metabolism of rat pancreatic islets in vitro
-
Sandler S, Bendtzen K, Eizirik DL & Welsh M 1990 Interleukin-6 affects insulin secretion and glucose metabolism of rat pancreatic islets in vitro. Endocrinology 126 1288-1294. (Pubitemid 20079554)
-
(1990)
Endocrinology
, vol.126
, Issue.2
, pp. 1288-1294
-
-
Sandler, S.1
Bendtzen, K.2
Eizirik, D.L.3
Welsh, M.4
-
42
-
-
0032478314
-
Fatty acid-induced beta cell apoptosis: A link between obesity and diabetes
-
Shimabukuro M, Zhou YT, Levi M & Unger RH 1998 Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes. PNAS 95 2498-2502.
-
(1998)
PNAS
, vol.95
, pp. 2498-2502
-
-
Shimabukuro, M.1
Zhou, Y.T.2
Levi, M.3
Unger, R.H.4
-
43
-
-
55849096988
-
Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes
-
Song B, Scheuner D, Ron D, Pennathur S & Kaufman RJ 2008 Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes. Journal of Clinical Investigation 118 3378-3389.
-
(2008)
Journal of Clinical Investigation
, vol.118
, pp. 3378-3389
-
-
Song, B.1
Scheuner, D.2
Ron, D.3
Pennathur, S.4
Kaufman, R.J.5
-
44
-
-
42449154297
-
Interaction between pro-inflammatory and anti-inflammatory cytokines in insulin-producing cells
-
DOI 10.1677/JOE-07-0638
-
Souza KL, Gurgul-Convey E, Elsner M & Lenzen S 2008 Interaction between pro-inflammatory and anti-inflammatory cytokines in insulin-producing cells. Journal of Endocrinology 197 139-150. (Pubitemid 351566933)
-
(2008)
Journal of Endocrinology
, vol.197
, Issue.1
, pp. 139-150
-
-
Souza, K.L.A.1
Gurgul-Convey, E.2
Elsner, M.3
Lenzen, S.4
-
45
-
-
0141644356
-
Effect of arachidonic acid on proliferation, cytokines production and pleiotropic genes expression in Jurkat cells - A comparison with oleic acid
-
Verlengia R, Gorjão R, Kanunfre CC, Bordin S, de Lima TM & Curi R 2003 Effect of arachidonic acid on proliferation, cytokines production and pleiotropic genes expression in Jurkat cells - a comparison with oleic acid. Life Sciences 73 2939-2951.
-
(2003)
Life Sciences
, vol.73
, pp. 2939-2951
-
-
Verlengia, R.1
Gorjão, R.2
Kanunfre, C.C.3
Bordin, S.4
De Lima, T.M.5
Curi, R.6
-
46
-
-
26244456414
-
ER stress and SREBP-1 activation are implicated in beta-cell glucolipotoxicity
-
Wang H, Kouri G & Wollheim CB 2005 ER stress and SREBP-1 activation are implicated in beta-cell glucolipotoxicity. Journal of Cell Science 118 3905-3915.
-
(2005)
Journal of Cell Science
, vol.118
, pp. 3905-3915
-
-
Wang, H.1
Kouri, G.2
Wollheim, C.B.3
-
47
-
-
0037147215
-
Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic β-cells (INS-1)
-
Wrede CE, Dickson LM, Lingohr MK, Briaud I & Rhodes CJ 2002 Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic β-cells (INS-1). Journal of Biological Chemistry 277 49676-49684.
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 49676-49684
-
-
Wrede, C.E.1
Dickson, L.M.2
Lingohr, M.K.3
Briaud, I.4
Rhodes, C.J.5
-
48
-
-
39649107702
-
ATF4-mediated induction of 4E-BP1 contributes to pancreatic beta cell survival under endoplasmic reticulum stress
-
Yamaguchi S, Ishihara H, Yamada T, Tamura A, Usui M, Tominaga R, Munakata Y, Satake C, Katagiri H, Tashiro F et al. 2008 ATF4-mediated induction of 4E-BP1 contributes to pancreatic beta cell survival under endoplasmic reticulum stress. Cell Metabolism 7 269-276.
-
(2008)
Cell Metabolism
, vol.7
, pp. 269-276
-
-
Yamaguchi, S.1
Ishihara, H.2
Yamada, T.3
Tamura, A.4
Usui, M.5
Tominaga, R.6
Munakata, Y.7
Satake, C.8
Katagiri, H.9
Tashiro, F.10
|