Insulin secretory defects and impaired islet architecture in pancreatic β-cell-specific STAT3 knockout mice

Biochemical and Biophysical Research Communications

Volumn 319, Issue 4, 2004, Pages 1159-1170

  Gorogawa, Shin Ichi ^a   Fujitani, Yoshio ^a,c   Kaneto, Hideaki ^a   Hazama, Yoji ^a   Watada, Hirotaka ^a   Miyamoto, Yasuhide ^a   Takeda, Kiyoshi ^b   Akira, Shizuo ^b   Magnuson, Mark A ^c   Yamasaki, Yoshimitsu ^a   Kajimoto, Yoshitaka ^a   Hori, Masatsugu ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cre; Diabetes; Insulin; LoxP; Pancreatic cell; STAT3

Indexed keywords

CRE RECOMBINASE; GLUCOSE TRANSPORTER 2; LEPTIN; STAT3 PROTEIN; VASCULOTROPIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APPETITE; ARTICLE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DIABETIC OBESITY; GENE DISRUPTION; GENETIC RECOMBINATION; GLUCOSE INTOLERANCE; HYPOTHALAMUS; INSULIN RELEASE; INSULIN RESISTANCE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSGENE;

ANIMALS; APPETITE; BLOOD GLUCOSE; BODY WEIGHT; CELL SIZE; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION; GLUCOSE TOLERANCE TEST; INSULIN; ISLETS OF LANGERHANS; LEPTIN; MALE; MICE; MICE, KNOCKOUT; OBESITY; PROMOTER REGIONS (GENETICS); RATS; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSGENES;

EID: 2942523253     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.05.095     Document Type: Article

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